Skip to Content

15,538 Results Found

  • Article
  • Open Access
3 Citations
2,567 Views
17 Pages

Manifold Regularized Principal Component Analysis Method Using L2,p-Norm

  • Minghua Wan,
  • Xichen Wang,
  • Hai Tan and
  • Guowei Yang

5 December 2022

The main idea of principal component analysis (PCA) is to transform the problem of high-dimensional space into low-dimensional space, and obtain the output sample set after a series of operations on the samples. However, the accuracy of the tradition...

  • Article
  • Open Access
5 Citations
3,131 Views
10 Pages

6 November 2022

Serum amyloid P component (SAP) may play an important role in human fungal diseases. SAP binds to functional amyloid on the fungal surface and masks fungi from host immune processes, skewing the macrophage population from the pro-inflammatory M1 to t...

  • Article
  • Open Access
4 Citations
3,363 Views
14 Pages

30 November 2023

In this paper, we presented a novel, compact, conceptually simple, and fully functional low-cost prototype of a pH sensor with a PANI thin film as a sensing layer. The PANI deposition process is truly low-cost; it performs from the liquid phase, does...

  • Article
  • Open Access
3 Citations
2,120 Views
35 Pages

Single-Step Response and Determination of Power Components Mean Values of PES Using p-q Method during Transients

  • Branislav Dobrucký,
  • Slavomír Kaščák,
  • Jozef Šedo,
  • Michal Praženica and
  • Patrik Resutík

16 November 2022

This paper deals with the quasi-instantaneous determination of an apparent-, active-, and reactive (i.e., blind and distortion) power mean values, including total power factor, total harmonic distortion, and phase shift of fundamentals of power elect...

  • Article
  • Open Access
20 Citations
3,869 Views
14 Pages

18 January 2021

To extend the application of the late waves of the event-related potentials (ERPs) to multiple modalities, devices and software the underlying physiological mechanisms and responses of the brain for a particular sensory system and mental function mus...

  • Article
  • Open Access
11 Citations
4,315 Views
22 Pages

Parametrizing the Conditionally Gaussian Prior Model for Source Localization with Reference to the P20/N20 Component of Median Nerve SEP/SEF

  • Atena Rezaei,
  • Marios Antonakakis,
  • MariaCarla Piastra,
  • Carsten H. Wolters and
  • Sampsa Pursiainen

3 December 2020

In this article, we focused on developing the conditionally Gaussian hierarchical Bayesian model (CG-HBM), which forms a superclass of several inversion methods for source localization of brain activity using somatosensory evoked potential (SEP) and...

  • Article
  • Open Access
518 Views
21 Pages

Role of the PhoP/PhoQ Two-Component Regulatory System in Biofilm Formation in Acid-Adapted Salmonella typhimurium

  • Huixuan Yang,
  • Xueqing Jiang,
  • George-John E. Nychas,
  • Kehui Yang,
  • Pengcheng Dong,
  • Yimin Zhang,
  • Lixian Zhu and
  • Yunge Liu

17 December 2025

Salmonella typhimurium is a global foodborne pathogen, and controlling its persistence is critical for public health. This study investigated the regulatory role of the PhoP/PhoQ two-component system (TCS) in biofilm formation under the acid adaptati...

  • Review
  • Open Access
3 Citations
3,717 Views
29 Pages

Pleiotropy of Progesterone Receptor Membrane Component 1 in Modulation of Cytochrome P450 Activity

  • Isabel S. Barata,
  • José Rueff,
  • Michel Kranendonk and
  • Francisco Esteves

1 May 2024

Progesterone receptor membrane component 1 (PGRMC1) is one of few proteins that have been recently described as direct modulators of the activity of human cytochrome P450 enzymes (CYP)s. These enzymes form a superfamily of membrane-bound hemoproteins...

  • Article
  • Open Access
2 Citations
1,270 Views
16 Pages

10 February 2025

Gynura divaricata (L.) DC is a long-used medicinal and edible plant in China folk. Its hyperglycemic effects have garnered increasing public attention in recent years. This study revealed that the ethyl acetate (EtOAc) and butanol (BuOH) partition fr...

  • Article
  • Open Access
8 Citations
4,667 Views
21 Pages

1 July 2020

Our study explores the factors influencing investors’ behavior in the peer-to-peer (P2P) lending market in China, and the relationships among them from the perspective of investors. The primary component analysis method was used to divide the P...

  • Article
  • Open Access
1,213 Views
21 Pages

27 November 2025

This study aimed to investigate the effects of acute exhaustion exercise on cognitive control in young men, a key higher cognitive function for goal-directed behavior. Although long-term regular exercise benefits cognition, the effects of acute exhau...

  • Article
  • Open Access
15 Citations
5,546 Views
15 Pages

29 July 2022

This paper introduces methodologies in forecasting oil prices (Brent and WTI) with multivariate time series of major S&P 500 stock prices using Gaussian process modeling, deep learning, and vine copula regression. We also apply Bayesian variable...

  • Article
  • Open Access
21 Citations
4,871 Views
21 Pages

22 August 2019

A valid seismic damage scene for indoor nonstructural components is critical for virtual earthquake safety drills which can teach occupants how to survive in earthquakes. A virtual scene construction method for the seismic damage of suspended ceiling...

  • Review
  • Open Access
8 Citations
4,359 Views
24 Pages

19 January 2024

4-Hydroxyphenylacetate 3-hydroxylase (4HPA3H) is a long-known class of two-component flavin-dependent monooxygenases from bacteria, including an oxygenase component (EC 1.14.14.9) and a reductase component (EC 1.5.1.36), with the latter being account...

  • Article
  • Open Access
20 Citations
4,238 Views
12 Pages

Preparation and Characterization of Pazopanib Hydrochloride-Loaded Four-Component Self-Nanoemulsifying Drug Delivery Systems Preconcentrate for Enhanced Solubility and Dissolution

  • Seung Ah Choi,
  • Eun Ji Park,
  • Jun Hak Lee,
  • Kyoung Ah Min,
  • Sung Tae Kim,
  • Dong-Jin Jang,
  • Han-Joo Maeng,
  • Sung Giu Jin and
  • Kwan Hyung Cho

The aim of this study was to develop a four-component self-nanoemulsifying drug delivery system (FCS) to enhance the solubility and dissolution of pazopanib hydrochloride (PZH). In the solubility test, PZH showed a highly pH-dependent solubility (pH...

  • Article
  • Open Access
488 Views
18 Pages

20 January 2026

Laboratory-based research on microbial fuel cells (MFCs) is often costly and limited to a small number of variables, making optimization challenging. However, machine learning (ML) offers a promising solution by enabling efficient multivariate princi...

  • Article
  • Open Access
8 Citations
4,590 Views
14 Pages

The locus of heat resistance (LHR) confers resistance to extreme heat, chlorine and oxidative stress in Escherichia coli. This study aimed to determine the function of the LHR in maintaining bacterial cell envelope homeostasis, the regulation of the...

  • Communication
  • Open Access
22 Citations
8,725 Views
10 Pages

LC/MS Guided Isolation of Alkaloids from Lotus Leaves by pH-Zone-Refining Counter-Current Chromatography

  • Xia Xu,
  • Cui-Rong Sun,
  • Xiao-Jing Dai,
  • Rui-Lin Hu,
  • Yuan-Jiang Pan and
  • Zhang-Fa Yang

18 March 2011

The traditional methods used in natural product separation primarily target the major components and the minor components may thus be lost during the separation procedure. Consequently, it’s necessary to develop efficient methods for the preparative...

  • Communication
  • Open Access
3 Citations
2,582 Views
12 Pages

3 January 2024

In order to reduce the asymmetric load acting on the blades of MW-class wind turbines, it is necessary to apply an individual pitch controller that independently adjusts the pitch angles of the three blades. This paper takes a new look at the relatio...

  • Review
  • Open Access
19 Citations
7,592 Views
25 Pages

26 December 2023

Panax ginseng C.A. Meyer (P. ginseng) is one of the more common traditional Chinese medicines (TCMs). It contains numerous chemical components and exhibits a range of pharmacological effects. An enormous burden is placed on people’s health and...

  • Article
  • Open Access
651 Views
16 Pages

22 October 2025

Nutrient stoichiometry and dissolved organic matter (DOM) govern essential ecosystem processes; however, their coupling in tea garden soils remains obscure, and cultivar-specific effects on this linkage remain virtually unknown. In this study, soil c...

  • Article
  • Open Access
11 Citations
3,953 Views
17 Pages

19 March 2020

In this paper, we evaluate the performance of the so-called parametric t-distributed stochastic neighbor embedding (P-t-SNE), comparing it to the performance of the t-SNE, the non-parametric version. The methodology used in this study is introduced f...

  • Article
  • Open Access
875 Views
16 Pages

Variations in C:N:P Stoichiometry and Non-Structural Carbohydrates in Different Parts of Pomelo (Citrus maxima) Flowers at Three Phenophases

  • Jiali Liao,
  • Shiyao Hu,
  • Yiming Kong,
  • Haohao Pan,
  • Maoyuan Zhu,
  • Ting Yu,
  • Hongling Hu,
  • Guoqing Zhuang and
  • Shun Gao

Carbon (C), nitrogen (N) and phosphorus (P), and non-structural carbohydrates (NSCs) are basic nutrients and energy sources for flower development. In this study, the morphological traits, C, N, P, and NSC concentrations, and C:N:P ratios in pistil,...

  • Article
  • Open Access
10 Citations
2,607 Views
21 Pages

New Insights on the Progesterone (P4) and PGRMC1/NENF Complex Interactions in Colorectal Cancer Progression

  • Joanna Kamińska,
  • Olga Martyna Koper-Lenkiewicz,
  • Donata Ponikwicka-Tyszko,
  • Weronika Lebiedzińska,
  • Ewelina Palak,
  • Maria Sztachelska,
  • Piotr Bernaczyk,
  • Justyna Dorf,
  • Katarzyna Guzińska-Ustymowicz and
  • Violetta Dymicka-Piekarska
  • + 3 authors

20 October 2023

The literature data regarding the risk of colorectal cancer (CRC) in the context of hormone therapy (HT), including both estrogen–progestogen combinations and estrogen alone, are inconclusive. The precise relationship underlying the action of p...

  • Article
  • Open Access
13 Citations
4,447 Views
14 Pages

Pulmonary Alveolar Stem Cell Senescence, Apoptosis, and Differentiation by p53-Dependent and -Independent Mechanisms in Telomerase-Deficient Mice

  • Kexiong Zhang,
  • Lihui Wang,
  • Xiaojing Hong,
  • Hao Chen,
  • Yao Shi,
  • Yingying Liu,
  • Jun Liu and
  • Jun-Ping Liu

26 October 2021

Pulmonary premature ageing and fibrogenesis as in idiopathic pulmonary fibrosis (IPF) occur with the DNA damage response in lungs deficient of telomerase. The molecular mechanism mediating pulmonary alveolar cell fates remains to be investigated. The...

  • Article
  • Open Access
16 Citations
5,308 Views
12 Pages

A Quadratic Regression Model to Quantify Plantation Soil Factors That Affect Tea Quality

  • Bo Wen,
  • Ruiyang Li,
  • Xue Zhao,
  • Shuang Ren,
  • Yali Chang,
  • Kexin Zhang,
  • Shan Wang,
  • Guiyi Guo and
  • Xujun Zhu

5 December 2021

Tea components (tea polyphenols, catechins, free amino acids, and caffeine) are the key factors affecting the quality of green tea. This study aimed to relate key biochemical substances in tea to soil nutrient composition and the effectiveness of fer...

  • Article
  • Open Access
3 Citations
1,821 Views
17 Pages

29 August 2023

Soil type is an important environmental factor that affects plant growth and development, especially during the early growth stage. In this study, P. chinense (Phellodendron chinense) seedlings were cultivated on red soil (RS), yellow soil (YS), acid...

  • Article
  • Open Access
15 Citations
3,401 Views
10 Pages

Higher Cognitive Reserve Is Associated with Better Working Memory Performance and Working-Memory-Related P300 Modulation

  • Gabriela Gutiérrez-Zamora Velasco,
  • Thalía Fernández,
  • Juan Silva-Pereyra,
  • Vicenta Reynoso-Alcántara and
  • Susana A. Castro-Chavira

This study aims to examine how two levels of cognitive reserve, as evidenced by reading syntactic skill, modify performance and neural activity in a two-load-level (high vs. low) working memory (WM) task. Two groups of participants with different rea...

  • Article
  • Open Access
24 Citations
6,876 Views
10 Pages

Marketable Yield of Potato and Its Quantitative Parameters after Application of Herbicides and Biostimulants

  • Krystyna Zarzecka,
  • Marek Gugała,
  • Anna Sikorska,
  • Kornelia Grzywacz and
  • Marek Niewęgłowski

Potato (Solanum tuberosum L.) is grown in over 160 countries. Weed competition and environmental stressors during the vegetative growth stage significantly impact crop yields. An experiment was conducted from 2012 to 2014 in Poland to assess the effe...

  • Article
  • Open Access
4 Citations
2,270 Views
15 Pages

Phosphate Uptake and Its Relation to Arsenic Toxicity in Lactobacilli

  • Daniela Corrales,
  • Cristina Alcántara,
  • María Jesús Clemente,
  • Dinoraz Vélez,
  • Vicenta Devesa,
  • Vicente Monedero and
  • Manuel Zúñiga

The use of probiotic lactobacilli has been proposed as a strategy to mitigate damage associated with exposure to toxic metals. Their protective effect against cationic metal ions, such as those of mercury or lead, is believed to stem from their chela...

  • Article
  • Open Access
16 Citations
4,315 Views
14 Pages

Raman spectroscopy, which is a suitable tool to elucidate the structural properties of intrinsically disordered proteins, was applied to investigate the changes in both the structure and the conformational heterogeneity of the DNA-binding domain (DBD...

  • Article
  • Open Access
5 Citations
3,125 Views
13 Pages

Many pharmaceutical products are electroactive and, therefore, can be determined by voltammetry. However, most of these substances produce signals in the same region of oxidative potentials, which makes it difficult to identify them. In this work, ch...

  • Article
  • Open Access
4 Citations
3,544 Views
22 Pages

3 February 2022

Precise identification of material sources is of great significance to archaeological study, conservation, and restoration of stone cultural relics. The present study proposes a simple and efficient approach to identifying the material source of ston...

  • Article
  • Open Access
35 Citations
5,009 Views
15 Pages

The Connection between Czc and Cad Systems Involved in Cadmium Resistance in Pseudomonas putida

  • Huizhong Liu,
  • Yu Zhang,
  • Yingsi Wang,
  • Xiaobao Xie and
  • Qingshan Shi

8 September 2021

Heavy metal pollution is widespread and persistent, and causes serious harm to the environment. Pseudomonas putida, a representative environmental microorganism, has strong resistance to heavy metals due to its multiple efflux systems. Although the f...

  • Article
  • Open Access
2,477 Views
24 Pages

10 November 2023

A comprehensive understanding of molecular interactions and functions is imperative for unraveling the intricacies of viral protein behavior and conformational dynamics during cellular entry. Focusing on the SARS-CoV-2 spike protein (SARS-CoV-2 sp),...

  • Article
  • Open Access
22 Citations
5,331 Views
17 Pages

3 April 2018

Tectonically-deformed coal (TDC) is a potential source of threats to coal-mining safety. Finding out the development and distribution of TDCs is a difficult task in coalfield seismic explorations. Based on the previous investigations, the P- to S-wav...

  • Article
  • Open Access
1 Citations
1,459 Views
12 Pages

14 September 2024

Pinus yunnanensis Franch., one of the pioneer species of wild mountain afforestation in southwest China, plays an essential role in the economy, society and environment of Yunnan Province. Nonetheless, P. yunnanensis’ trunk twisting and bending...

  • Proceeding Paper
  • Open Access
1,383 Views
6 Pages

Preliminary Assessment of Microbiological and Physicochemical Properties of Artisanal “Chouriço de Carne” Fermented Sausages, Manufactured in Northern Portugal

  • Ana Sofia Faria,
  • Gisela Rodrigues,
  • Rebeca Becker Miranda,
  • Olga María Bonilla-Luque,
  • Laís Carvalho,
  • Nathália Fernandes,
  • Miguel Angel Prieto,
  • Vasco Cadavez and
  • Ursula Gonzales-Barron

“Chouriço de carne” is a Portuguese ready-to-eat dry fermented sausage which relies on effective spontaneous fermentation to ensure its microbial safety and desired organoleptic properties. This study aimed to assess selected micro...

  • Article
  • Open Access
50 Citations
3,970 Views
19 Pages

19 February 2019

In recent years, more and more attention has been paid to wind energy throughout the world as a kind of clean and renewable energy. Due to doubts concerning wind power and the influence of natural factors such as weather, unpredictability, and the ri...

  • Feature Paper
  • Article
  • Open Access
14 Citations
5,052 Views
10 Pages

An Improved Method for the Sensitive Detection of Shiga Toxin 2 in Human Serum

  • Xiaohua He,
  • Gianluigi Ardissino,
  • Stephanie Patfield,
  • Luisa W. Cheng,
  • Christopher J. Silva and
  • Maurizio Brigotti

31 January 2018

Shiga toxins (Stx) released by Stx-producing E. coli (STEC) are virulence factors that are most closely associated with hemolytic uremic syndrome (HUS), a life-threatening complication of intestinal infections by STEC. Stx have to enter into the circ...

  • Article
  • Open Access
4 Citations
1,203 Views
18 Pages

17 March 2025

Understanding the spatial distribution patterns of soil organic carbon components in Ecological Vegetative Slopes (EVS) is crucial for optimizing restoration strategies, enhancing soil carbon sequestration capacity, and scientifically evaluating reha...

  • Article
  • Open Access
1 Citations
2,160 Views
29 Pages

24 August 2024

Advanced 1H Nuclear Magnetic Resonance (NMR) relaxometry and diffusometry methods and VIS-nearIR spectroscopy combined with pH, electrical conductivity (EC) and totally dissolved solids (TDSSs) measurements were used to assess the properties of waste...

  • Article
  • Open Access
4 Citations
3,559 Views
7 Pages

Do Pentraxins Bind to Fungi in Invasive Human Gastrointestinal Candidiasis?

  • Umamaheshwari Golconda,
  • Richard E. Sobonya and
  • Stephen A. Klotz

17 September 2018

Tissue from 13 autopsy cases with invasive gastrointestinal candidiasis was studied for the binding of the pentraxins, C-reactive protein (CRP), pentraxin 3 (PTX3), and serum amyloid P component (SAP) to fungal surfaces. Invasive candidal infection w...

  • Article
  • Open Access
2 Citations
3,616 Views
15 Pages

16 September 2020

This study presents a new approach to exploring human inhibition in a realistic scenario. In previous inhibition studies, the stimulus design of go/no-go task generally used a simple symbol for the go and stop signals. We can understand the neural ac...

  • Article
  • Open Access
8 Citations
1,948 Views
17 Pages

1 July 2022

Bear time records, which are the accumulations of spatial spectrum estimates on the time axis, are often employed for passive sonar information processing. Multi-target jamming is a common difficulty in this approach due to the constraints of Rayleig...

  • Article
  • Open Access
35 Citations
5,462 Views
20 Pages

Evaluation of Grid-Based Rainfall Products and Water Balances over the Mekong River Basin

  • Kha Dang Dinh,
  • Tran Ngoc Anh,
  • Nhu Y Nguyen,
  • Du Duong Bui and
  • Raghavan Srinivasan

8 June 2020

Gridded precipitation products (GPPs) with wide spatial coverage and easy accessibility are well recognized as a supplement to ground-based observations for various hydrological applications. The error properties of satellite rainfall products vary a...

  • Communication
  • Open Access
10 Citations
5,047 Views
14 Pages

Enantioselective Epoxidation by Flavoprotein Monooxygenases Supported by Organic Solvents

  • Daniel Eggerichs,
  • Carolin Mügge,
  • Julia Mayweg,
  • Ulf-Peter Apfel and
  • Dirk Tischler

19 May 2020

Styrene and indole monooxygenases (SMO and IMO) are two-component flavoprotein monooxygenases composed of a nicotinamide adenine dinucleotide (NADH)-dependent flavin adenine dinucleotide (FAD)-reductase (StyB or IndB) and a monooxygenase (StyA or Ind...

  • Article
  • Open Access
5 Citations
5,506 Views
10 Pages

Go/No-Go Ratios Modulate Inhibition-Related Brain Activity: An Event-Related Potential Study

  • Nan Zhang,
  • Weichao An,
  • Yinghua Yu,
  • Jinglong Wu and
  • Jiajia Yang

(1) Background: Response inhibition refers to the conscious ability to suppress behavioral responses, which is crucial for effective cognitive control. Currently, research on response inhibition remains controversial, and the neurobiological mechanis...

  • Article
  • Open Access
27 Citations
4,225 Views
20 Pages

Dissection of P2X4 and P2X7 Receptor Current Components in BV-2 Microglia

  • Mira Trang,
  • Günther Schmalzing,
  • Christa E. Müller and
  • Fritz Markwardt

11 November 2020

Microglia cells represent the immune system of the central nervous system. They become activated by ATP released from damaged and inflamed tissue via purinergic receptors. Ionotropic purinergic P2X4 and P2X7 receptors have been shown to be involved i...

of 311