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  • Article
  • Open Access
3 Citations
1,508 Views
18 Pages

The LSmAD Domain of Ataxin-2 Modulates the Structure and RNA Binding of Its Preceding LSm Domain

  • Shengping Zhang,
  • Yunlong Zhang,
  • Ting Chen,
  • Hong-Yu Hu and
  • Changrui Lu

6 March 2025

Ataxin-2 (Atx2), an RNA-binding protein, plays a pivotal role in the regulation of RNA, intracellular metabolism, and translation within the cellular environment. Although both the Sm-like (LSm) and LSm-associated (LSmAD) domains are considered to as...

  • Article
  • Open Access
42 Citations
5,876 Views
24 Pages

Potential Therapeutic and Prognostic Values of LSM Family Genes in Breast Cancer

  • Hoang Dang Khoa Ta,
  • Wei-Jan Wang,
  • Nam Nhut Phan,
  • Nu Thuy An Ton,
  • Gangga Anuraga,
  • Su-Chi Ku,
  • Yung-Fu Wu,
  • Chih-Yang Wang and
  • Kuen-Haur Lee

29 September 2021

In recent decades, breast cancer (BRCA) has become one of the most common diseases worldwide. Understanding crucial genes and their signaling pathways remain an enormous challenge in evaluating the prognosis and possible therapeutics. The “Like-Smith...

  • Article
  • Open Access
6 Citations
3,140 Views
17 Pages

Comprehensive Bioinformatics Analysis of the Biodiversity of Lsm Proteins in the Archaea Domain

  • Gloria Payá,
  • Vanesa Bautista,
  • Mónica Camacho,
  • Julia Esclapez and
  • María-José Bonete

The Sm protein superfamily includes Sm, like-Sm (Lsm), and Hfq proteins. Sm and Lsm proteins are found in the Eukarya and Archaea domains, respectively, while Hfq proteins exist in the Bacteria domain. Even though Sm and Hfq proteins have been extens...

  • Article
  • Open Access
3 Citations
2,736 Views
17 Pages

Yeast Lsm Pro-Apoptotic Mutants Show Defects in Autophagy

  • Benedetta Caraba,
  • Mariarita Stirpe,
  • Vanessa Palermo,
  • Ugo Vaccher,
  • Michele Maria Bianchi,
  • Claudio Falcone and
  • Cristina Mazzoni

5 September 2023

LSM4 is an essential yeast gene encoding a component of different LSM complexes involved in the regulation of mRNA splicing, stability, and translation. In previous papers, we reported that the expression in S. cerevisiae of the K. lactis LSM4 gene l...

  • Article
  • Open Access
7 Citations
2,381 Views
20 Pages

Analysis of Lsm Protein-Mediated Regulation in the Haloarchaeon Haloferax mediterranei

  • Gloria Payá,
  • Vanesa Bautista,
  • Sandra Pastor-Soler,
  • Mónica Camacho,
  • Julia Esclapez and
  • María-José Bonete

The Sm protein superfamily includes Sm, like-Sm (Lsm), and Hfq found in the Eukarya, Archaea, and Bacteria domains. Archaeal Lsm proteins have been shown to bind sRNAs and are probably involved in various cellular processes, suggesting a similar func...

  • Article
  • Open Access
9 Citations
4,042 Views
9 Pages

YSZ/LSM Composite Cathode Deposited by Solution Precursor Plasma Spraying

  • Xiaoming Wang,
  • Boen Tang,
  • Penghui Wen,
  • Weiping Dong,
  • Linlin Wang and
  • Dongyun Wang

28 February 2022

In this paper, solution precursor plasma spraying (SPPS) was employed to prepare a porous YSZ/LSM composite cathode for solid oxide fuel cell (SOFC). The surface morphology and microstructure of the composite cathode deposits were characterized using...

  • Article
  • Open Access
1,472 Views
21 Pages

SwiftKV: A Metadata Indexing Scheme Integrating LSM-Tree and Learned Index for Distributed KV Stores

  • Zhenfei Wang,
  • Jianxun Feng,
  • Longxiang Dun,
  • Ziliang Bao and
  • Chunfeng Du

30 August 2025

Optimizing metadata indexing remains critical for enhancing distributed file system performance. The Traditional Log-Structured Merge-Trees (LSM-Trees) architecture, while effective for write-intensive operations, exhibits significant limitations whe...

  • Article
  • Open Access
5 Citations
2,530 Views
19 Pages

19 February 2024

This study addresses the challenge of accurately estimating hourly flow and soil moisture by integrating the Soil and Water Assessment Tool (SWAT) with a Land Surface Model (LSM). Our approach enhances SWAT by incorporating spatially distributed soil...

  • Article
  • Open Access
3 Citations
2,402 Views
14 Pages

17 October 2023

The conventional Ni–YSZ (yttria-stabilized zirconia) fuel electrode experiences severe degradation due to Ni- agglomeration and migration away from the electrolyte. Therefore, herein, we have considered Ni free electrodes, i.e., La0.6Sr0.4MnO3-...

  • Article
  • Open Access
1 Citations
1,545 Views
11 Pages

Prediction of Clinical Trajectory in HCV-Related ACLD after SVR: Role of Liver Stiffness in a 5-Years Prospective Study

  • Filomena Morisco,
  • Alessandro Federico,
  • Massimo Marignani,
  • Flavia L. Lombardo,
  • Valentina Cossiga,
  • Luisa Ranieri,
  • Mario Romeo,
  • Marina Cipullo,
  • Paola Begini and
  • Tommaso Stroffolini
  • + 1 author

10 September 2024

The prediction of liver-related events (LRE) after sustained virological response (SVR) in HCV-advanced chronic liver disease (ACLD) patients is crucial. We aimed to evaluate incidence and risk factors of LRE in HCV-cirrhotic patients after SVR and t...

  • Review
  • Open Access
10 Citations
4,902 Views
32 Pages

Assimilation of Satellite-Derived Soil Moisture and Brightness Temperature in Land Surface Models: A Review

  • Reza Khandan,
  • Jean-Pierre Wigneron,
  • Stefania Bonafoni,
  • Arastoo Pour Biazar and
  • Mehdi Gholamnia

7 February 2022

The correction of Soil Moisture (SM) estimates in Land Surface Models (LSMs) is considered essential for improving the performance of numerical weather forecasting and hydrologic models used in weather and climate studies. Along with surface screen-l...

  • Article
  • Open Access
31 Citations
4,234 Views
23 Pages

2 June 2023

Landslides pose a serious threat to human lives and property. Accurate landslide susceptibility mapping (LSM) is crucial for sustainable development. Machine learning has recently become an important means of LSM. However, the accuracy of machine lea...

  • Article
  • Open Access
61 Citations
5,904 Views
18 Pages

Sub-Sonic Linear Synchronous Motors Using Superconducting Magnets for the Hyperloop

  • Su Y. Choi,
  • Chang Y. Lee,
  • Jung M. Jo,
  • Jae H. Choe,
  • Ye Jun Oh,
  • Kwan S. Lee and
  • Jung Y. Lim

4 December 2019

Sub-sonic linear synchronous motors (LSMs) with high-temperature superconducting (HTS) magnets, which aim to accelerate to a velocity of 1200 km/h in the near-vacuum tubes of 0.001 atm for the Hyperloop, are newly introduced in this paper. By the vir...

  • Article
  • Open Access
12 Citations
3,939 Views
9 Pages

Semiconductor-Ionic Nanocomposite La0.1Sr0.9MnO3−δ-Ce0.8Sm0.2O2−δ Functional Layer for High Performance Low Temperature SOFC

  • Zhaoqing Wang,
  • Xunying Wang,
  • Zhaoyun Xu,
  • Hui Deng,
  • Wenjing Dong,
  • Baoyuan Wang,
  • Chu Feng,
  • Xueqi Liu and
  • Hao Wang

28 August 2018

A novel composite was synthesized by mixing La0.1Sr0.9MnO3−δ (LSM) with Ce0.8Sm0.2O2−δ (SDC) for the functional layer of low temperature solid oxide fuel cell (LT-SOFC). Though LSM, a highly electronic conducting semiconductor...

  • Article
  • Open Access
86 Citations
11,821 Views
20 Pages

Fuzzy Shannon Entropy: A Hybrid GIS-Based Landslide Susceptibility Mapping Method

  • Majid Shadman Roodposhti,
  • Jagannath Aryal,
  • Himan Shahabi and
  • Taher Safarrad

27 September 2016

Assessing Landslide Susceptibility Mapping (LSM) contributes to reducing the risk of living with landslides. Handling the vagueness associated with LSM is a challenging task. Here we show the application of hybrid GIS-based LSM. The hybrid approach e...

  • Article
  • Open Access
26 Citations
8,291 Views
17 Pages

Landslides are one of the most damaging geological hazards in mountainous regions such as the Himalayas. The Himalayan region is, tectonically, the most active region in the world that is highly vulnerable to landslides and associated hazards. Landsl...

  • Article
  • Open Access
722 Views
57 Pages

Bioinformatic Analyses of the Ataxin-2 Family Since Algae Emphasize Its Small Isoforms, Large Chimerisms, and the Importance of Human Exon 1B as Target of Therapies to Prevent Neurodegeneration

  • Georg W. J. Auburger,
  • Jana Key,
  • Suzana Gispert,
  • Isabel Lastres-Becker,
  • Luis-Enrique Almaguer-Mederos,
  • Carole Bassa,
  • Antonius Auburger,
  • Georg Auburger,
  • Aleksandar Arsovic and
  • Nesli-Ece Sen
  • + 1 author

3 February 2026

Polyglutamine expansion in Ataxin-2 (ATXN2) is responsible for rare, dominantly inherited Spinocerebellar Ataxia type 2 (SCA2). Together with its paralog Ataxin-2-like (ATXN2L), both proteins have received much interest, since the deletion of their y...

  • Article
  • Open Access
206 Citations
10,015 Views
29 Pages

Landslide Susceptibility Evaluation and Management Using Different Machine Learning Methods in The Gallicash River Watershed, Iran

  • Alireza Arabameri,
  • Sunil Saha,
  • Jagabandhu Roy,
  • Wei Chen,
  • Thomas Blaschke and
  • Dieu Tien Bui

3 February 2020

This analysis aims to generate landslide susceptibility maps (LSMs) using various machine learning methods, namely random forest (RF), alternative decision tree (ADTree) and Fisher’s Linear Discriminant Function (FLDA). The results of the FLDA,...

  • Article
  • Open Access
637 Views
18 Pages

13 February 2026

Reservoir computing (RC) has emerged as an energy-efficient paradigm for temporal information processing, offering reduced training complexity by fixing recurrent dynamics and training only a simple readout layer. Among RC models, Echo State Networks...

  • Article
  • Open Access
2,156 Views
22 Pages

Compaction-Aware Flash Memory Remapping for Key–Value Stores

  • Jialin Wang,
  • Zhen Yang,
  • Yi Fan and
  • Yajuan Du

11 June 2025

With the rapid development of big data and artificial intelligence, the demand for memory has exploded. As a key data structure in modern databases and distributed storage systems, the Log-Structured Merge Tree (LSM-tree) has been widely employed (su...

  • Article
  • Open Access
30 Citations
3,840 Views
27 Pages

An Assessment of Negative Samples and Model Structures in Landslide Susceptibility Characterization Based on Bayesian Network Models

  • Sahand Khabiri,
  • Matthew M. Crawford,
  • Hudson J. Koch,
  • William C. Haneberg and
  • Yichuan Zhu

20 June 2023

Landslide susceptibility mapping (LSM) characterizes landslide potential, which is essential for assessing landslide risk and developing mitigation strategies. Despite the significant progress in LSM research over the past two decades, several long-s...

  • Article
  • Open Access
503 Views
16 Pages

Assessment of Liver Fibrosis Stage and Cirrhosis Regression After Long-Term Follow-Up Following Sustained Virological Response

  • Lidia Canillas,
  • Dolores Naranjo,
  • Teresa Broquetas,
  • Juan Sánchez,
  • Anna Pocurull,
  • Esther Garrido,
  • Rosa Fernández,
  • Xavier Forns and
  • José A. Carrión

Background/Objectives: Previous studies have demonstrated that the cessation of liver damage after HCV cure can improve liver function, histological necroinflammation, and portal hypertension. However, scarce data about fibrosis stage or cirrhosis re...

  • Article
  • Open Access
21 Citations
4,916 Views
20 Pages

A Novel Rule-Based Approach in Mapping Landslide Susceptibility

  • Majid Shadman Roodposhti,
  • Jagannath Aryal and
  • Biswajeet Pradhan

16 May 2019

Despite recent advances in developing landslide susceptibility mapping (LSM) techniques, resultant maps are often not transparent, and susceptibility rules are barely made explicit. This weakens the proper understanding of conditioning criteria invol...

  • Article
  • Open Access
1 Citations
2,631 Views
16 Pages

Leveraging Soil Moisture Assimilation in Permafrost Affected Regions

  • Ankita Pradhan,
  • Akhilesh S. Nair,
  • J. Indu,
  • Olga Makarieva and
  • Nataliia Nesterova

10 March 2023

The transfer of water and energy fluxes between the ground and the atmosphere is influenced by soil moisture (SM), which is an important factor in land surface dynamics. Accurate representation of SM over permafrost-affected regions remains challengi...

  • Article
  • Open Access
9 Citations
3,587 Views
19 Pages

21 May 2019

The microstructure of hypereutectic immiscible Cu-50Cr alloy (wt%) was effectively refined and homogenized by a high power density Nd:YAG continuous laser beam (power density 104–105 MW/m2). The average grain size of Cr was effectively refined...

  • Article
  • Open Access
1,428 Views
16 Pages

An Over-Deterministic Method for Mode III SIF Calculation Using Full-Field Experimental Displacement Fields

  • Jorge Guillermo Díaz-Rodríguez,
  • Cesar Hernando Valencia-Niño and
  • Andrés Rodríguez-Torres

20 March 2025

The paper proposes and tests an approach to determine the stress intensity factors (SIF) of cracks subjected to mode III using full-field displacements as opposed to the crack opening displacement (COD) method, which uses only two data points. The pr...

  • Article
  • Open Access
1 Citations
1,596 Views
18 Pages

11 October 2024

Dimensional and profile measurements of deep-hole parts are key processes both in manufacturing and product lifecycle management. Due to the particularity of the space conditions of deep-hole parts, the existing measurement instruments and methods ex...

  • Article
  • Open Access
39 Citations
5,710 Views
27 Pages

Evaluation of Different Landslide Susceptibility Models for a Local Scale in the Chitral District, Northern Pakistan

  • Bilal Aslam,
  • Ahsen Maqsoom,
  • Umer Khalil,
  • Omid Ghorbanzadeh,
  • Thomas Blaschke,
  • Danish Farooq,
  • Rana Faisal Tufail,
  • Salman Ali Suhail and
  • Pedram Ghamisi

19 April 2022

This work evaluates the performance of three machine learning (ML) techniques, namely logistic regression (LGR), linear regression (LR), and support vector machines (SVM), and two multi-criteria decision-making (MCDM) techniques, namely analytical hi...

  • Article
  • Open Access
49 Citations
7,200 Views
18 Pages

In this paper we report our results from analysing a hybrid spatial multi-criteria evaluation (SMCE) method for generating landslide susceptibility mapping (LSM). This study is the first of its kind in the Kullu valley, Himalayas. We used eight relat...

  • Article
  • Open Access
12 Citations
5,012 Views
17 Pages

CMADS-Driven Simulation and Analysis of Reservoir Impacts on the Streamflow with a Simple Statistical Approach

  • Ningpeng Dong,
  • Mingxiang Yang,
  • Xianyong Meng,
  • Xuan Liu,
  • Zhaokai Wang,
  • Hao Wang and
  • Chuanguo Yang

21 January 2019

The reservoir operation is a notable source of uncertainty in the natural streamflow and it should be represented in hydrological modelling to quantify the reservoir impact for more effective hydrological forecasting. While many researches focused on...

  • Article
  • Open Access
729 Views
30 Pages

25 December 2025

Zero-day intrusions on IoT endpoints demand defenses that curtail attacker impact and persistence after breach. This article presents Fine-Grained Runtime Containment Agent (FG-RCA), a lightweight post-exploitation containment system that learns leas...

  • Article
  • Open Access
1,985 Views
23 Pages

3 July 2025

Land surface models (LSMs) play a crucial role in climate prediction and carbon cycle assessment. To ensure their reliability, it is crucial to evaluate their performance in simulating key processes, such as evapotranspiration (ET) and gross primary...

  • Article
  • Open Access
5 Citations
3,516 Views
26 Pages

4 February 2020

Wall-model large eddy simulations (WMLES) are conducted to investigate the spatial features of large-scale and very-large-scale motions (LSMs and VLSMs) in turbulent boundary flow in different surface roughnesses at a very high Reynolds number, O (10...

  • Article
  • Open Access
14 Citations
5,206 Views
13 Pages

Light-Sheet Microscopy for Surface Topography Measurements and Quantitative Analysis

  • Zhanpeng Xu,
  • Erik Forsberg,
  • Yang Guo,
  • Fuhong Cai and
  • Sailing He

16 May 2020

A novel light-sheet microscopy (LSM) system that uses the laser triangulation method to quantitatively calculate and analyze the surface topography of opaque samples is discussed. A spatial resolution of at least 10 μm in z-direction, 10 μm in...

  • Article
  • Open Access
2 Citations
3,019 Views
14 Pages

Synthesis of Ag-La0.8Sr0.2MnO3 (LSM-Ag) Composite Powder and Its Application in Magnesium Air Battery

  • Xiaohan Wu,
  • Hui Liu,
  • Jiaxi Zhang,
  • Juemin Song,
  • Jiefeng Huang,
  • Wanli Xu,
  • Yang Yan and
  • Kun Yu

13 April 2021

La0.8Sr0.2MnO3 (LSM) catalyst is prepared via a sol-gel method and modified via a typical silver mirror reaction. Silver ammonia solution is reduced in a polyvinylpyrrolidone (PVP)-containing solution to obtain silver nanoparticles and sodium dodecyl...

  • Review
  • Open Access
29 Citations
3,984 Views
42 Pages

12 July 2023

The progressive research trends in the development of low-cost, commercially competitive solid oxide fuel cells with reduced operating temperatures are closely linked to the search for new functional materials as well as technologies to improve the p...

  • Article
  • Open Access
12 Citations
5,524 Views
8 Pages

DC 4-Point Measurement for Total Electrical Conductivity of SOFC Cathode Material

  • Kanghee Jo,
  • Jooyeon Ha,
  • Jiseung Ryu,
  • Eunkyung Lee and
  • Heesoo Lee

28 May 2021

Conductive oxides are widely studied as cathode materials for electrochemical cells, such as solid oxide fuel cells (SOFCs), because of their chemical stability and high electrical conductivity at high temperatures (800–950 °C). The cathode is a key...

  • Article
  • Open Access
1 Citations
2,576 Views
17 Pages

HoaKV: High-Performance KV Store Based on the Hot-Awareness in Mixed Workloads

  • Jingyu Liu,
  • Xiaoqin Fan,
  • Youxi Wu,
  • Yong Zheng and
  • Lu Liu

Key–value (KV) stores based on the LSM-tree have become the mainstream of contemporary store engines, but there are problems with high write and read amplification. Moreover, the real-world workload has a high data skew, and the existing KV sto...

  • Article
  • Open Access
37 Citations
5,600 Views
15 Pages

Cement-Stabilized Waste Sand as Sustainable Construction Materials for Foundations and Highway Roads

  • Faisal I. Shalabi,
  • Javed Mazher,
  • Kaffayatullah Khan,
  • Mohammed Alsuliman,
  • Ibrahim Almustafa,
  • Ward Mahmoud and
  • Naif Alomran

17 February 2019

In this study, cement-treated waste sand as a by-product material produced from Al-Ahsa quarries (Saudi Arabia) was experimentally tested and investigated as a base course material for the foundation of structures and roads. The study aimed to use th...

  • Article
  • Open Access
8 Citations
4,780 Views
18 Pages

On Surrogate-Based Optimization of Truly Reversible Blade Profiles for Axial Fans

  • Gino Angelini,
  • Tommaso Bonanni,
  • Alessandro Corsini,
  • Giovanni Delibra,
  • Lorenzo Tieghi and
  • David Volponi

20 June 2018

Open literature offers a wide canvas of techniques for surrogate-based multi-objective optimization. The large majority of works focus on methodological and theoretical aspects and are applied to simple mathematical functions. The present work aims a...

  • Feature Paper
  • Article
  • Open Access
3 Citations
2,574 Views
12 Pages

Evaluation of Structural and Functional Properties of La0.6Sr0.4MnO3 Perovskite Prepared by the Fast Solution Combustion Approach

  • Ramón Cobo Rendón,
  • Christopher Salvo,
  • Erwin Sepúlveda,
  • Arunachalam Arulraj,
  • Felipe Sanhueza,
  • José Jiménez Rodríguez and
  • Ramalinga Viswanathan Mangalaraja

13 December 2022

A series of La0.6Sr0.4MnO3 (LSM) perovskite was made using the rapid solution combustion method, which was calcined by varying the temperatures. In order to determine how the calcination temperature affected the nanopowders produced and calcined at v...

  • Article
  • Open Access
767 Views
18 Pages

Calorie Restriction Suppresses Premature Ageing in Pro-Apoptotic Yeast Mutants Through an Autophagy-Independent Mechanism

  • Benedetta Caraba,
  • Mariarita Stirpe,
  • Vanessa Palermo,
  • Alessia Ayala Alban,
  • Arianna Montanari,
  • Michele Maria Bianchi,
  • Claudio Falcone and
  • Cristina Mazzoni

The budding yeast Saccharomyces cerevisiae has long served as a valuable model for investigating the molecular mechanisms underlying aging. Calorie restriction (CR) is a well-established intervention that extends lifespan across species, yet the unde...

  • Review
  • Open Access
4 Citations
4,430 Views
16 Pages

Differential Polarization Imaging of Plant Cells. Mapping the Anisotropy of Cell Walls and Chloroplasts

  • Jasna Simonović Radosavljević,
  • Aleksandra Lj. Mitrović,
  • Ksenija Radotić,
  • László Zimányi,
  • Győző Garab and
  • Gábor Steinbach

Modern light microscopy imaging techniques have substantially advanced our knowledge about the ultrastructure of plant cells and their organelles. Laser-scanning microscopy and digital light microscopy imaging techniques, in general—in addition to th...

  • Article
  • Open Access
23 Citations
4,088 Views
18 Pages

14 September 2021

The accurate detection and alleviation of driving fatigue are of great significance to traffic safety. In this study, we tried to apply the modified multi-scale entropy (MMSE) approach, based on variational mode decomposition (VMD), to driving fatigu...

  • Article
  • Open Access
7 Citations
3,793 Views
23 Pages

17 September 2019

Image recovery from compressive sensing (CS) measurement data, especially noisy data has always been challenging due to its implicit ill-posed nature, thus, to seek a domain where a signal can exhibit a high degree of sparsity and to design an effect...

  • Article
  • Open Access
10 Citations
2,924 Views
14 Pages

1 June 2020

The high rate of change of frequency (RoCoF) issue incurred by the integration of renewable energy sources (RESs) into a modern power system significantly threatens the grid security, and thus needs to be carefully examined in the operational plannin...

  • Article
  • Open Access
9 Citations
3,524 Views
29 Pages

25 January 2023

Landslides pose a great threat to the safety of people’s lives and property within disaster areas. In this study, the Zigui to Badong section of the Three Gorges Reservoir is used as the study area, and the land use (LU), land use change (LUC)...

  • Review
  • Open Access
25 Citations
6,632 Views
33 Pages

Cytosolic Sensors for Pathogenic Viral and Bacterial Nucleic Acids in Fish

  • Miriam Mojzesz,
  • Krzysztof Rakus,
  • Magdalena Chadzinska,
  • Kentaro Nakagami,
  • Gouranga Biswas,
  • Masahiro Sakai and
  • Jun-ichi Hikima

2 October 2020

Recognition of the non-self signature of invading pathogens is a crucial step for the initiation of the innate immune mechanisms of the host. The host response to viral and bacterial infection involves sets of pattern recognition receptors (PRRs), wh...

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