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302 Results Found

  • Article
  • Open Access
3 Citations
4,444 Views
12 Pages

5 July 2021

The Wall-modeled Large-eddy Simulation (WMLES) methods are commonly accompanied with an underprediction of the skin friction and a deviation of the velocity profile. The widely-used Improved Delayed Detached Eddy Simulation (IDDES) method is suggeste...

(This article belongs to the Special Issue Turbulent Flow)
  • Article
  • Open Access
34 Citations
6,160 Views
39 Pages

Effects of Near Wall Modeling in the Improved-Delayed-Detached-Eddy-Simulation (IDDES) Methodology

  • Rohit Saini,
  • Nader Karimi,
  • Lian Duan,
  • Amsini Sadiki and
  • Amirfarhang Mehdizadeh

8 October 2018

The present study aims to assess the effects of two different underlying RANS models on overall behavior of the IDDES methodology when applied to different flow configurations ranging from fully attached (plane channel flow) to separated flows (perio...

(This article belongs to the Special Issue Intermittency and Self-Organisation in Turbulence and Statistical Mechanics)
  • Article
  • Open Access
2 Citations
2,986 Views
25 Pages

1 September 2025

Traditional hybrid RANS/LES methods often struggle to accurately capture both the boundary layer transition and flow separation simultaneously due to their reliance on fully turbulent RANS models. To address this limitation, the present study first e...

(This article belongs to the Section Turbulence)
  • Article
  • Open Access
7 Citations
3,376 Views
12 Pages

Sheath blight (ShB) caused by Rhizoctonia solani is a major disease of rice, seriously affecting yield; however, the molecular defense mechanism against ShB remains unclear. A previous transcriptome analysis of rice identified that R. solani inoculat...

(This article belongs to the Special Issue Molecular Genetics of Rice Disease Resistance)
  • Article
  • Open Access
1 Citations
2,380 Views
20 Pages

The slots on a blade tip can effectively suppress the tip vortices by diffusing the core structure of a vortex and thus mitigate the adverse impacts of vortex interactions. In this paper, the effect of a slotted tip on vortex diffusion in the hoverin...

(This article belongs to the Section Aeronautics)
  • Article
  • Open Access
2,574 Views
23 Pages

Genome-Wide Characterization of the INDETERMINATE DOMAIN (IDD) Zinc Finger Gene Family in Solanum lycopersicum and the Functional Analysis of SlIDD15 in Shoot Gravitropism

  • Huan Wu,
  • Mingli Liu,
  • Yuqi Fang,
  • Jing Yang,
  • Xiaoting Xie,
  • Hailong Zhang,
  • Dian Zhou,
  • Yueqiong Zhou,
  • Yexin He and
  • Quanzi Bai
  • + 1 author

27 September 2024

The plant-specific IDD transcription factors (TFs) are vital for regulating plant growth and developmental processes. However, the characteristics and biological roles of the IDD gene family in tomato (Solanum lycopersicum) are still largely unexplor...

(This article belongs to the Special Issue Advances in Plant Genomics and Genetics)
  • Article
  • Open Access
6 Citations
2,350 Views
23 Pages

28 June 2025

This study investigates dynamic stall mechanisms of a pitching NACA 0012 airfoil through high-fidelity computational fluid dynamics (CFD) simulations. The improved delayed detached eddy simulation (IDDES) method based on a sliding mesh system is cons...

  • Article
  • Open Access
6 Citations
6,834 Views
31 Pages

16 May 2023

Racecar aerodynamic development requires well-correlated simulation data for rapid and incremental development cycles. Computational Fluid Dynamics (CFD) simulations and wind tunnel testing are industry-wide tools to perform such development, and the...

(This article belongs to the Special Issue Aerodynamics and Aeroacoustics of Vehicles, 3rd Edition)
  • Article
  • Open Access
460 Views
20 Pages

9 June 2026

INDETERMINATE DOMAIN (IDD) transcription factors are plant-specific regulators essential for plant development and stress adaptation. As a globally important staple crop, common wheat (Triticum aestivum L.) is frequently threatened by fungal diseases...

(This article belongs to the Section Plant Science)
  • Article
  • Open Access
4 Citations
2,337 Views
18 Pages

13 August 2024

The indeterminate domain proteins (IDD proteins) play essential roles in the growth and development of various plant tissues and organs across different developmental stages, but members of this gene family have not yet been characterized in foxtail...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Article
  • Open Access
17 Citations
4,430 Views
17 Pages

Transcription factors (TFs) are important regulators of numerous gene expressions due to their ability to recognize and combine cis-elements in the promoters of target genes. The INDETERMINATE DOMAIN (IDD) gene family belongs to a subfamily of C2H2 z...

(This article belongs to the Special Issue Genomics-Based Tree Breeding to Improve Resilience in the Face of Global Climate Change)
  • Article
  • Open Access
9 Citations
2,817 Views
22 Pages

Genome-Wide Identification of the Highly Conserved INDETERMINATE DOMAIN (IDD) Zinc Finger Gene Family in Moso Bamboo (Phyllostachys edulis)

  • Xiaoqin Guo,
  • Minshu Zhou,
  • Jiaoyu Chen,
  • Mingxia Shao,
  • Longhai Zou,
  • Yeqing Ying and
  • Shenkui Liu

12 November 2022

INDETERMINATE DOMAIN (IDD) proteins, a family of transcription factors unique to plants, function in multiple developmental processes. Although the IDD gene family has been identified in many plants, little is known about it in moso bamboo. In this p...

(This article belongs to the Special Issue Transcriptional Regulation in Plant Development)
  • Article
  • Open Access
1,474 Views
19 Pages

Genome-Wide Identification of the Dendrocalamus latiflorus IDD Gene Family and Its Functional Role in Bamboo Shoot Development

  • Yu-Han Lin,
  • Peng-Kai Zhu,
  • Mei-Yin Zeng,
  • Xin-Ru Gao,
  • Tian-You He,
  • Jun-Dong Rong,
  • Yu-Shan Zheng and
  • Ling-Yan Chen

30 August 2025

Background: Transcription factors (TFs) critically regulate gene expression, orchestrating plant growth, development, and stress responses. The conserved IDD (INDETERMINATE DOMAIN) TF family modulates key developmental processes, including root, stem...

(This article belongs to the Special Issue Genetic and Functional Genomics Insights into the Genetic Improvement of Stress Resistance in Economic Crops)
  • Article
  • Open Access
817 Views
20 Pages

Genome-Wide Identification of the IDD Gene Family in Soybean (Glycine max) and Their Expression Profiles in Response to Drought, Salt Stress, and Different Photoperiod Conditions

  • Rouxing Li,
  • Zixiang Ning,
  • Zhihui Dong,
  • Jian Xi,
  • Chenjie Shi,
  • Xianlian Chen,
  • Qingyuan He,
  • Shaochuang Chuang,
  • Xue Yang and
  • Yingjie Shu

20 April 2026

Background: INDETERMINATE DOMAIN proteins (IDDs) are a plant-specific transcription factor family, and members of this family play crucial roles in regulating growth and development as well as environmental adaptation. However, a comprehensive analys...

(This article belongs to the Section Plant Genetics and Genomics)
  • Article
  • Open Access
2,864 Views
17 Pages

21 February 2024

Medical professionals are rarely trained to treat the unique healthcare needs and health disparities of people with intellectual and developmental disabilities (IDD). The Curriculum in IDD Healthcare (CIDDH) eLearn course aims to redress gaps in the...

  • Proceeding Paper
  • Open Access
1 Citations
2,095 Views
7 Pages

A Methodology for the Digitalization of the Residential Building Renovation Process through IDDS Ready Workflows

  • Alberto Armijo,
  • Peru Elguezabal,
  • Mohamed Elagiry,
  • Natalia Lasarte and
  • Andrea Costa

The European building industry is facing a strong increase of renovation processes, which are still non-cost-effective, involve unproperly coordinated stakeholders, are disturbing for the occupants, and imply important inefficiencies of the overall r...

(This article belongs to the Proceedings of The 8th Annual International Sustainable Places Conference (SP2020) Proceedings)
  • Article
  • Open Access
2 Citations
4,650 Views
12 Pages

11 June 2023

INDETERMINATE DOMAIN (IDD) proteins are plant-specific transcription factors that interact with GRAS proteins, such as DELLA and SHORT ROOT (SHR), to regulate target genes. The combination of IDD and DELLA proteins regulates genes involved in gibbere...

(This article belongs to the Section Plant Genetics and Genomics)
  • Review
  • Open Access
7 Citations
3,074 Views
16 Pages

24 September 2024

INDETERMINATE DOMAIN (IDD) genes encode plant-specific transcription factors containing a conserved IDD domain with four zinc finger motifs. Previous studies on Arabidopsis IDDs (AtIDDs) have demonstrated that these genes play roles in diverse physio...

(This article belongs to the Special Issue Molecular Breeding and Genetic Regulation of Crops)
  • Article
  • Open Access
28 Citations
6,172 Views
18 Pages

2 June 2020

INDETERMINATE DOMAIN (IDD) family proteins are plant-specific transcription factors. Some Arabidopsis IDD (AtIDD) proteins regulate the expression of SCARECROW (SCR) by interacting with GRAS family transcription factors SHORT-ROOT (SHR) and SCR, whic...

(This article belongs to the Section Plant Genetics and Genomics)
  • Article
  • Open Access
24 Citations
7,239 Views
15 Pages

8 October 2019

Paclitaxel-lipoate (IDD-1040) is a conjugate formed by the chemical joining of the two compounds, by condensing a lipoic acid moiety to the C2′ of paclitaxel. IDD-1040 was evaluated for its anti-tumor activity and potential druggability, using...

(This article belongs to the Special Issue Bioactive Phytochemicals for Cancer Prevention and Treatment)
  • Article
  • Open Access
10 Citations
4,427 Views
17 Pages

Complex Diagnostics of Non-Specific Intellectual Developmental Disorder

  • Olga Levchenko,
  • Elena Dadali,
  • Ludmila Bessonova,
  • Nina Demina,
  • Galina Rudenskaya,
  • Galina Matyushchenko,
  • Tatiana Markova,
  • Inga Anisimova,
  • Natalia Semenova and
  • Alexander Lavrov
  • + 6 authors

Intellectual development disorder (IDD) is characterized by a general deficit in intellectual and adaptive functioning. In recent years, there has been a growing interest in studying the genetic structure of IDD. Of particular difficulty are patients...

(This article belongs to the Special Issue Molecular Genetics and Genomics in Human Hereditary Diseases in Russia)
  • Article
  • Open Access
1,782 Views
20 Pages

Numerical Methods Comparison of Shock-Induced Separation on Transonic Axisymmetric Hump

  • Miao Zhang,
  • Zhuoyue Tian,
  • Songxiang Tang,
  • Ziyan Wei and
  • Jie Li

7 November 2024

A transonic hump with a Mach number (M∞) of 0.875 was utilized to compare the prediction capabilities of RANS, URANS, IDDES, and IDDES-SLA for shock-induced separation. The results matched the experimental data concerning pressure, friction coe...

  • Review
  • Open Access
10 Citations
4,277 Views
11 Pages

Dysphoria and Irritability—Diagnostic Pitfalls in the Assessment of Interictal Dysphoric Disorder in Epilepsy

  • Agata M. Grzegorzewska,
  • Mariusz S. Wiglusz,
  • Wiesław J. Cubała,
  • Katarzyna Jakuszkowiak-Wojten,
  • Adam Włodarczyk and
  • Joanna Szarmach

8 October 2021

This article aims to review the concept of epilepsy-specific psychiatric disturbance, Interictal Dysphoric Disorder (IDD), focusing on issues related to its core symptoms and methodological pitfalls. In the psychiatric literature, an epilepsy-specifi...

(This article belongs to the Special Issue Current Challenges and Advances in the Treatment of Epilepsy)
  • Article
  • Open Access
9 Citations
4,248 Views
20 Pages

14 December 2021

The strong change in the flow fields around two maglev trains (MTs) passing each other in open air may affect their manoeuvrability and passengers’ comfort. In this study, we evaluated the aerodynamic performance of two MTs passing each other v...

  • Article
  • Open Access
14 Citations
2,922 Views
20 Pages

20 December 2021

This paper is concerned with certain non-linear unperturbed and perturbed systems of integro-delay differential equations (IDDEs). We investigate fundamental properties of solutions such as uniformly stability (US), uniformly asymptotically stability...

(This article belongs to the Special Issue New Advances in Functional Analysis)
  • Article
  • Open Access
5 Citations
3,180 Views
18 Pages

31 May 2025

Curved surfaces are a feature of many engineering applications, and as such, the accurate prediction of separation and reattachment from a curved surface is of great engineering importance. In this study, improved delayed detached eddy simulation (ID...

(This article belongs to the Special Issue Industrial CFD and Fluid Modelling in Engineering, 3rd Edition)
  • Article
  • Open Access
6 Citations
2,888 Views
22 Pages

9 February 2023

The paper deals with the self-ignition and combustion of hydrogen jets in a high-speed transverse flow of hot vitiated air in a duct. The Improved Delayed Detached Eddy Simulation (IDDES) approach based on the Shear Stress Transport (SST) model is us...

(This article belongs to the Special Issue Experiments and Simulations of Combustion Process)
  • Article
  • Open Access
2 Citations
1,306 Views
29 Pages

Current therapeutic strategies for intervertebral disc degeneration (IDD)-related low back pain are limited to symptomatic alleviation. Notochordal cells (NCs), as progenitor cells of the nucleus pulposus (NP), lead us to develop innovative NC-based...

(This article belongs to the Section Molecular Medicine)
  • Article
  • Open Access
8 Citations
3,160 Views
18 Pages

24 October 2024

The Improved Delayed Detached-Eddy Simulation (IDDES) is a modification of the original Detached-Eddy Simulation (DES) design to incorporate Wall Modeled Large Eddy Simulation (WMLES) capabilities and to extend the class of flows suitable for this me...

(This article belongs to the Special Issue Industrial CFD and Fluid Modelling in Engineering, 2nd Edition)
  • Article
  • Open Access
2 Citations
2,005 Views
12 Pages

Factors Associated with Adverse Birth Outcomes in Women with an Intellectual or Other Developmental Disability

  • Kyle Bradford Jones,
  • Isabel K. Taylor,
  • Tyson Schwab,
  • Camille King,
  • Godwin Okoye and
  • Jaewhan Kim

Objective. Women with intellectual or developmental disabilities (IDDs) experience poorer prenatal care and worse perinatal health and birth outcomes than the general population. The purpose of this study is to describe the maternal characteristics a...

(This article belongs to the Special Issue Maternal and Child Health: Advances in Translational Research)
  • Article
  • Open Access
1 Citations
2,523 Views
16 Pages

A New Hope for All-Diamond Electrodes? The Interdigitated Double Diamond Electrode

  • Manuel Zulla,
  • Carolin Messerschmidt,
  • Hanadi Ghanem,
  • Johannes Bähr,
  • Lukas Hegemann and
  • Stefan Rosiwal

Nowadays, the development of efficient water treatment processes is increasingly driven by the need to provide solutions for contaminants of emerging concern. Electrochemical advanced oxidation processes (EAOPs) based on diamond electrodes can be par...

(This article belongs to the Special Issue Feature Papers in Electrochemistry)
  • Article
  • Open Access
752 Views
31 Pages

Crosswind-Induced Hazards of Railway Bridge Auxiliary Fixtures: An IDDES Study on Walkway Slabs and Cable Troughs

  • Hongkai Yan,
  • Tanghong Liu,
  • Xiaodong Chen,
  • Haowei Cheng,
  • Hongrui Gao and
  • Xifeng Liang

14 November 2025

This study presents a comprehensive numerical investigation into the aerodynamic behavior of pedestrian walkway slabs and cable troughs mounted on high-speed railway bridges under crosswind conditions. Using a full-scale T-beam bridge model with auxi...

(This article belongs to the Section Transportation and Future Mobility)
  • Review
  • Open Access
3 Citations
3,730 Views
20 Pages

Intrathecal Drug Delivery Systems for Chronic Pain Management: A Narrative Review of Pharmacologic Agents, Clinical Applications, and Considerations

  • Milan Patel,
  • Alison J. Deng,
  • Madelyn Reilly,
  • Mariam Morcus,
  • Alyssa McKenzie,
  • Lukas Henjum,
  • Alan D. Kaye and
  • Alaa Abd-Elsayed

16 December 2025

This narrative review seeks to delve into the different on and off-label medications commonly used with intrathecal drug delivery systems (IDDS) and their clinical applications specifically in pain management settings. This review utilizes a variety...

  • Article
  • Open Access
3 Citations
1,957 Views
23 Pages

This study explored how mathematics teachers in Chinese special schools provide instructional support to primary-aged students with intellectual and developmental disabilities (IDD). The types, characteristics, and classroom implementation processes...

(This article belongs to the Section Approaches to Improving Intelligence)
  • Review
  • Open Access
143 Citations
8,289 Views
15 Pages

The Proteolysis of ECM in Intervertebral Disc Degeneration

  • Huaizhen Liang,
  • Rongjin Luo,
  • Gaocai Li,
  • Weifeng Zhang,
  • Yu Song and
  • Cao Yang

2 February 2022

Intervertebral disc (IVD) degeneration (IDD) is a pathological process that commonly occurs throughout the human life span and is a major cause of lower back pain. Better elucidation of the molecular mechanisms involved in disc degeneration could pro...

(This article belongs to the Special Issue Proteolysis of Extracellular Matrix in Human Disease 2.0)
  • Review
  • Open Access
4 Citations
1,238 Views
32 Pages

Immunometabolism: A Novel Therapeutic Target and Its Pharmacological Modulation for Intervertebral Disc Degeneration

  • Mengting Cheng,
  • Yichen Liu,
  • Moran Suo,
  • Kaizhong Wang,
  • Xin Chen and
  • Zhonghai Li

23 January 2026

Intervertebral disc degeneration (IDD) is a leading cause of low back pain (LBP) and imposes a substantial social and economic burden. Current treatments mainly relieve symptoms but rarely halt or reverse disc degeneration, and key gaps remain in our...

(This article belongs to the Section Molecular Immunology)
  • Review
  • Open Access
1,337 Views
26 Pages

HME-FDM 3D-Printed Implantable Drug Delivery Systems-From Design to Characterization

  • Bence Vámosi,
  • Ildikó Bácskay,
  • Pálma Fehér,
  • Zoltán Ujhelyi and
  • Petra Arany

Implantable devices have undergone enormous development in the past several decades and more results are expected as there are still unanswered questions. In manufacturing, a relatively new technology called three-dimensional (3D) printing has become...

(This article belongs to the Special Issue Advances in Solid and Semi-Solid Dosage Form Design for Enhanced Biopharmaceutical Performance)
  • Article
  • Open Access
4 Citations
2,485 Views
13 Pages

29 November 2022

Road scene segmentation is an integral part of the Intelligent Transport System (ITS) for precise interpretation of the environment and safer vehicle navigation. Traditional segmentation methods have faced difficulties in meeting the requirements of...

(This article belongs to the Section Computing and Artificial Intelligence)
  • Article
  • Open Access
6 Citations
7,028 Views
23 Pages

28 January 2023

As the need to discovers new mineral deposits and occurrences has intensified in recent years, it has become increasingly apparent that we need to map potentials via integrated information on the basis of metallogeny. Occurrences of mineralization su...

(This article belongs to the Section Mineral Exploration Methods and Applications)
  • Article
  • Open Access
449 Views
11 Pages

28 April 2026

Background: Malnutrition is a universal challenge in long-term care, significantly affecting vulnerable populations. Residents with Intellectual Developmental Disability (IDD) rely heavily on Direct Support Professionals (DSPs) for assisted feeding....

(This article belongs to the Special Issue Nutritional Nursing and Rehabilitation in Hospital and Long-Term Care Settings)
  • Article
  • Open Access
3 Citations
2,267 Views
34 Pages

13 January 2025

This study provides a detailed analysis of the convergence criteria for dynamic mode decomposition (DMD) parameters, with a focus on sampling frequency and period in high-Reynolds-number flows. The analysis is based on flow over an idealized road veh...

(This article belongs to the Special Issue Trends and Prospects in Vehicle System Dynamics)
  • Article
  • Open Access
13 Citations
7,488 Views
11 Pages

2 August 2021

The Insurance Distribution Directive (IDD) aims to regulate insurance distribution in the EU regardless of distribution channels and means. Although new technologies affect insurance distribution, the IDD does not explicitly regulate this digital tra...

(This article belongs to the Special Issue The Risk Landscape within FinTech and InsurTech Business Models)
  • Article
  • Open Access
2 Citations
1,789 Views
22 Pages

Improved Delayed Detached Eddy Simulation of Combustion of Hydrogen Jets in a High-Speed Confined Hot Air Cross Flow II: New Results

  • Sergei Bakhne,
  • Vladimir Vlasenko,
  • Alexei Troshin,
  • Vladimir Sabelnikov and
  • Andrey Savelyev

26 October 2023

The improved delayed detached Eddy simulation (IDDES) approach used in the part I of this investigation to study the self-ignition and combustion of hydrogen jets in a high-speed transverse flow of hot vitiated air in a duct is extended in the follow...

(This article belongs to the Special Issue Experiments and Simulations of Combustion Process II)
  • Article
  • Open Access
360 Views
20 Pages

18 May 2026

Flow-induced vibration of high-speed pantographs becomes increasingly important as train speed approaches and exceeds 400 km/h. This paper develops an efficient computational framework that couples component-resolved unsteady aerodynamic loads from i...

(This article belongs to the Special Issue Mathematical Modeling in Structural Mechanics)
  • Article
  • Open Access
2 Citations
1,839 Views
28 Pages

Aerodynamic Performance of a Natural Laminar Flow Swept-Back Wing for Low-Speed UAVs Under Take Off/Landing Flight Conditions and Atmospheric Turbulence

  • Nikolaos K. Lampropoulos,
  • Ioannis E. Sarris,
  • Spyridon Antoniou,
  • Odysseas Ziogas,
  • Pericles Panagiotou and
  • Kyros Yakinthos

16 October 2025

The topic of the present study is the aerodynamic performance of a Natural Laminar Flow (NLF) wing for UAVs at low speed. The basis is a thoroughly tested NLF airfoil in the wind tunnel of NASA which is well-customized for light aircrafts. The aim of...

(This article belongs to the Section Aeronautics)
  • Case Report
  • Open Access
8 Citations
9,450 Views
10 Pages

Background. Heterozygous pathogenic variants in the DDX3X gene account for 1–3% of females with intellectual and developmental disabilities (IDD). The clinical presentation is variable, including a wide range of neurological and behavioral defi...

(This article belongs to the Section Developmental Neuroscience)
  • Article
  • Open Access
24 Citations
5,867 Views
20 Pages

Aerodynamic Performance of a High-Speed Train Passing through Three Standard Tunnel Junctions under Crosswinds

  • Xiujuan Miao,
  • Kan He,
  • Guglielmo Minelli,
  • Jie Zhang,
  • Guangjun Gao,
  • Hongliang Wei,
  • Maosheng He and
  • Sinisa Krajnovic

26 May 2020

The aerodynamic performance of a high-speed train passing through tunnel junctions under severe crosswind condition was numerically investigated using improved delayed detached-eddy simulations (IDDES). Three ground scenarios connected with entrances...

(This article belongs to the Section Mechanical Engineering)
  • Article
  • Open Access
1 Citations
1,685 Views
14 Pages

27 November 2023

The hydrodynamic performance and wake evaluation results of a cantilever flexible cylindrical triangular array at Re = 9000 and with L/D spacing ratios ranging from 3 to 7 are presented in this paper. The improved delayed separation eddy current simu...

  • Article
  • Open Access
22 Citations
3,623 Views
12 Pages

Assessment of Psychopathology in Adolescents with Insulin-Dependent Diabetes (IDD) and the Impact on Treatment Management

  • Maria Melania Lica,
  • Annamaria Papai,
  • Andreea Salcudean,
  • Maria Crainic,
  • Cristina Georgeta Covaciu and
  • Adriana Mihai

Assessing mental health in children and adolescents with insulin-dependent diabetes (IDD) is an issue that is underperformed in clinical practice and outpatient clinics. The evaluation of their thoughts, emotions and behaviors has an important role i...

  • Article
  • Open Access
15 Citations
2,905 Views
12 Pages

19 November 2022

Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune and degenerative disease with axonal damage and demyelination as its main features. Its dual neurological and autoimmune nature makes it a disease that is difficult to treat. Treatments t...

(This article belongs to the Special Issue Role of Phosphodiesterase in Biology and Pathology 2.0)

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