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55 Results Found

  • Article
  • Open Access
7 Citations
2,801 Views
10 Pages

Is There a Dose–Response Relationship between High-Intensity Interval Exercise (HIIE) Intensity and Affective Valence? Analysis of Three HIIE Sessions Performed with Different Amplitudes

  • Michel Oliveira Silva,
  • Tony Meireles Santos,
  • Allan Inoue,
  • Lucas Eduardo Rodrigues Santos and ,
  • Weydyson de Lima do Nascimento Anastácio,
  • Eduardo Lattari and
  • Bruno Ribeiro Ramalho Oliveira
  • + 2 authors+ 0 author

The inverse relationship between exercise intensity and affective valence is well established for continuous exercise but not for high-intensity interval exercise (HIIE). The objective was to verify the dose–response relationship between exerci...

(This article belongs to the Section Exercise and Health)
  • Article
  • Open Access
9 Citations
4,551 Views
9 Pages

HIIE Protocols Promote Better Acute Effects on Blood Glucose and Pressure Control in People with Type 2 Diabetes than Continuous Exercise

  • Gabriela de Oliveira Teles,
  • Paulo Gentil,
  • Lucas Raphael Bento e Silva,
  • Wátila de Moura Sousa and ,
  • Camila Simões Seguro and
  • Ana Cristina Silva Rebelo
  • + 1 author+ 0 author

This study compared the acute effects of a session of different high-intensity interval exercise (HIIE) protocols and a session of moderate-intensity continuous exercise (MICE) on blood glucose, blood pressure (BP), and heart rate (HR) in people with...

(This article belongs to the Special Issue Diabetes in Sports and Exercise Medicine)
  • Article
  • Open Access
21 Citations
4,449 Views
12 Pages

This study examined the immediate and sustained effects of high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE) bouts on inhibitory control in young adults. Participants (n = 41) engaged in (1) a session of HIIE,...

(This article belongs to the Section Exercise and Health)
  • Article
  • Open Access
277 Views
14 Pages

30 September 2026

Background/Objectives: To compare the acute effects of high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE) on executive-function performance, prefrontal oxyhaemoglobin (Oxy-Hb) signals, brain-derived neurotrophic...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Article
  • Open Access
11 Citations
5,166 Views
12 Pages

This study aimed to evaluate the effects of high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE) on cognitive flexibility in young adults with differing levels of aerobic fitness. Sixty-six young adults were group...

(This article belongs to the Special Issue 2nd Edition of Sport Modalities, Performance and Health)
  • Article
  • Open Access
3,266 Views
10 Pages

Exploring an Unknown Corner of a Well-Known Topic: HIIE Influence on Renal Health and Filtration in Healthy Individuals Free of Cardiometabolic Diseases

  • Jeffrey S. Forsse,
  • Kathleen A. Richardson,
  • Ricardo Torres,
  • Catherine Lowry and ,
  • James Kyle Taylor,
  • Cassidy L. Beeson,
  • Jacob Ward,
  • Anurag Dhillon,
  • Brock Niceler and
  • Panagiotis Koutakis
  • + 6 authors+ 1 author

30 October 2023

Aerobic exercise, specifically high-intensity interval exercise (HIIE), and its effects on renal health and filtration (RHF) are not well understood. Several studies support incorporating contemporary biomarkers serum cystatin C (CyC) and urine epide...

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)
  • Article
  • Open Access
9 Citations
4,278 Views
18 Pages

Semaglutide and High-Intensity Interval Exercise Attenuate Cognitive Impairment in Type 2 Diabetic Mice via BDNF Modulation

  • Sijie Lai,
  • Zhenghong Kang,
  • Jianting Sun,
  • Ziyu Wang and ,
  • Yanzi Xu,
  • Sisi Xing,
  • Mengying Feng,
  • Yiyi Wang and
  • Hua Liu
  • + 4 authors+ 0 author

Background/Objectives: Diabetes frequently leads to cognitive impairment, encompassing issues with memory and executive function, as well as depression and anxiety. This study examines the impact of high-intensity interval exercise (HIIE) alongside g...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Comment
  • Open Access
1 Citations
2,095 Views
2 Pages

After a careful appraisal, we are concerned that the article “HIIE Protocols Promote Better Acute Effects on Blood Glucose and Pressure Control in People with Type 2 Diabetes than Continuous Exercise” [...]

(This article belongs to the Special Issue Diabetes in Sports and Exercise Medicine)
  • Article
  • Open Access
3 Citations
2,731 Views
13 Pages

Researchers have hypothesized that high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MOD) lead to different patterns of shear stress in the brachial artery. These differing patterns of shear stress are thought to par...

(This article belongs to the Special Issue Exercise Physiology and Biochemistry: 2nd Edition)
  • Article
  • Open Access
8 Citations
3,921 Views
10 Pages

Affective Responses during High-Intensity Interval Exercise Compared with Moderate-Intensity Continuous Exercise in Inactive Women

  • I-Hua Chu,
  • Pei-Tzu Wu,
  • Wen-Lan Wu,
  • Hsiang-Chi Yu and ,
  • Tzu-Cheng Yu and
  • Yu-Kai Chang
  • + 1 author+ 0 author

This study aimed to investigate the effects of an acute bout of high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE) on affective responses in inactive women. Thirty women with normal body mass index (BMI) and 30...

  • Article
  • Open Access
16 Citations
4,201 Views
11 Pages

29 January 2022

Acute aerobic high-intensity interval exercise (HIIE) has demonstrated positive effects on inhibitory control and P3 event-related potential (ERP) in young adults. However, the evidence is not well established regarding the effects of different HIIE...

(This article belongs to the Section Behavioral Neuroscience)
  • Article
  • Open Access
6 Citations
4,387 Views
10 Pages

Home-Based High-Intensity Interval Exercise Improves the Postprandial Glucose Response in Young Adults with Postprandial Hyperglycemia

  • Yuto Nakayama,
  • Kumiko Ono,
  • Junya Okagawa,
  • Junji Urabe and ,
  • Ryoga Yamau and
  • Akira Ishikawa
  • + 1 author+ 0 author

Postprandial hyperglycemia can be corrected by exercise; however, the effect of home-based high-intensity interval exercise (HIIE), a new time-efficient exercise, on glycemic control is unclear. This study aimed to investigate the effect of home-base...

(This article belongs to the Special Issue The Health Outcomes of High-Intensity Interval Exercise and Training)
  • Article
  • Open Access
6 Citations
4,433 Views
19 Pages

27 August 2023

Type 1 diabetes (T1D) is associated with hyperglycaemia-induced hypoxia and inflammation. This study assessed the effects of a single bout of high-intensity interval exercise (HIIE) on glycaemia (BG) and serum level of pro-inflammatory cytokines, and...

(This article belongs to the Special Issue Sports Nutrition: Current and Novel Insights)
  • Article
  • Open Access
6 Citations
4,471 Views
11 Pages

Effect of Exercise Duration on Postprandial Glycaemic and Insulinaemic Responses in Adolescents

  • Karah J. Dring,
  • Simon B. Cooper,
  • Ryan A. Williams,
  • John G. Morris and ,
  • Caroline Sunderland and
  • Mary E. Nevill
  • + 1 author+ 0 author

12 March 2020

High-intensity intermittent exercise (HIIE) is a potential intervention to manage hyperglycaemia and insulin resistance in adolescents. The aim of this study was to determine the optimum duration of HIIE to reduce postprandial glycaemic and insulinae...

(This article belongs to the Special Issue Metabolic Adaptations to Diet and Physical Activity)
  • Article
  • Open Access
5 Citations
7,216 Views
17 Pages

People practicing high-intensity interval exercise (HIIE) fasted during the morning hours under a lack of sleep. Such a habit may jeopardize the health benefits related to HIIE and adequate sleep. Fifteen habitually good sleeper males (age 31.1 ± 5.3...

(This article belongs to the Special Issue The Health Outcomes of High-Intensity Interval Exercise and Training)
  • Article
  • Open Access
2 Citations
2,793 Views
12 Pages

A Cardiopulmonary Exercise Testing for Prescribing High-Intensity Interval Training Sessions with Elastic Resistance

  • Lorena Flores Duarte,
  • Victor Hugo Gasparini-Neto,
  • Letícia Nascimento Santos Neves,
  • Lenice Brum Nunes and ,
  • Richard Diego Leite,
  • Nuno Manoel Frade de Sousa and
  • Luciana Carletti
  • + 2 authors+ 0 author

This study aims to analyze the agreement of cardiopulmonary variables between a cardiopulmonary exercise test with elastic resistance (CPxEL) and high-intensity interval exercise with elastic resistance (EL-HIIE). Methods: Twenty-two physically indep...

(This article belongs to the Section Exercise and Health-Related Quality of Life)
  • Article
  • Open Access
6 Citations
3,993 Views
10 Pages

Central Hemodynamic Adjustments during Post-Exercise Hypotension in Hypertensive Patients with Ischemic Heart Disease: Concurrent Circuit Exercise versus High-Intensity Interval Exercise. A Preliminary Study

  • Giuseppe Caminiti,
  • Ferdinando Iellamo,
  • Marco Alfonso Perrone,
  • Valentino D’Antoni and ,
  • Matteo Catena,
  • Vincenzo Manzi,
  • Valentina Morsella,
  • Alessio Franchini and
  • Maurizio Volterrani
  • + 4 authors+ 0 author

15 December 2021

Concurrent aerobic plus resistance exercise (RAE) and high-intensity interval exercise (HIIE) are both effective at inducing post-exercise hypotension (PEH) in patients with hypertension. However, central hemodynamic changes associated with PEH in hy...

(This article belongs to the Special Issue Advances in the Diagnosis and Treatment of Coronary Artery Disease)
  • Article
  • Open Access
9 Citations
6,309 Views
22 Pages

23 March 2021

The effluents of wastewater treatment plants (WWTPs) are major contributors of nutrients, microbes—including those carrying antibiotic resistance genes (ARGs)—and pathogens to receiving waterbodies. The effect of the effluent of a small-scale activat...

(This article belongs to the Special Issue Risk Assessment of Water Resources and Food: Microbial Contaminants, Antibiotics and Antibiotic Resistance Genes)
  • Article
  • Open Access
29 Citations
6,084 Views
24 Pages

Assessment of Hydrocarbon Degradation Potential in Microbial Communities in Arctic Sea Ice

  • Angela Peeb,
  • Nga Phuong Dang,
  • Marika Truu,
  • Hiie Nõlvak and ,
  • Chris Petrich and
  • Jaak Truu
  • + 1 author+ 0 author

The anthropogenic release of oil hydrocarbons into the cold marine environment is an increasing concern due to the elevated usage of sea routes and the exploration of new oil drilling sites in Arctic areas. The aim of this study was to evaluate proka...

(This article belongs to the Special Issue Oil Biodegradation and Bioremediation in Cold Marine Environment)
  • Article
  • Open Access
29 Citations
6,571 Views
23 Pages

Microbial Community Dynamics during Biodegradation of Crude Oil and Its Response to Biostimulation in Svalbard Seawater at Low Temperature

  • Hiie Nõlvak,
  • Nga Phuong Dang,
  • Marika Truu,
  • Angela Peeb and ,
  • Kertu Tiirik,
  • Megan O’Sadnick and
  • Jaak Truu
  • + 2 authors+ 0 author

The development of oil exploration activities and an increase in shipping in Arctic areas have increased the risk of oil spills in this cold marine environment. The objective of this experimental study was to assess the effect of biostimulation on mi...

(This article belongs to the Special Issue Oil Biodegradation and Bioremediation in Cold Marine Environment)
  • Article
  • Open Access
21 Citations
8,668 Views
12 Pages

The Pharmacokinetic Profile and Bioavailability of Enteral N-Acetylcysteine in Intensive Care Unit

  • Kersti Teder,
  • Liivi Maddison,
  • Hiie Soeorg,
  • Andres Meos and
  • Juri Karjagin

8 November 2021

Background and Objectives: N-acetylcysteine (NAC) is a mucolytic agent used to prevent ventilator-associated pneumonia in intensive care units. This study aimed to evaluate the oral bioavailability of NAC in critically ill patients with pneumonia, is...

(This article belongs to the Section Pharmacology)
  • Article
  • Open Access
18 Citations
7,749 Views
25 Pages

Dynamics of Bacterial Community Abundance and Structure in Horizontal Subsurface Flow Wetland Mesocosms Treating Municipal Wastewater

  • Kristjan Oopkaup,
  • Marika Truu,
  • Hiie Nõlvak,
  • Teele Ligi and ,
  • Jens-Konrad Preem,
  • Ülo Mander and
  • Jaak Truu
  • + 2 authors+ 0 author

17 October 2016

Dynamics of bacterial community abundance and structure of a newly established horizontal subsurface flow (HSSF) pilot-scale wetland were studied using high-throughput sequencing and quantitative polymerase chain reaction (PCR) methods. Bacterial com...

(This article belongs to the Special Issue Constructed Wetlands for Water Treatment: New Developments)
  • Abstract
  • Open Access
1 Citations
1,557 Views
2 Pages

Silver Nanoparticles May Promote Antibiotic Resistance Gene Persistence in Wastewater Treatment Systems

  • Marika Truu,
  • Teele Ligi,
  • Hiie Nõlvak,
  • Angela Peeb and ,
  • Kertu Tiirik,
  • Arun Devarajan,
  • Margit Kõiv-Vainik,
  • Kuno Kasak,
  • Kaja Kasemets and
  • Jaak Truu
  • + 5 authors+ 0 author

Silver nanoparticles (AgNPs) rank as some of the most commonly utilized engineered nanomaterials and are known to enter wastewater collection and treatment systems through their creation, application, and disposal processes [...]

(This article belongs to the Proceedings of International Conference EcoBalt 2023 "Chemicals & Environment")
  • Article
  • Open Access
1 Citations
1,697 Views
19 Pages

The Impact of the Natural Level of Blood Biochemicals on Electroencephalographic Markers in Healthy People

  • Laura Päeske,
  • Hiie Hinrikus,
  • Jaanus Lass,
  • Toomas Põld and
  • Maie Bachmann

21 November 2024

This study aims to investigate the association between the natural level of blood biomarkers and electroencephalographic (EEG) markers. Resting EEG theta, alpha (ABP), beta, and gamma frequency band powers were selected as linear EEG markers indicati...

(This article belongs to the Section Biomedical Sensors)
  • Article
  • Open Access
1 Citations
3,551 Views
20 Pages

Quantitative Differences in the Human Intestinal Microbiota Through the Stages of Life: Infants, Children, Adults and the Elderly

  • Jelena Štšepetova,
  • Natalja Šebunova,
  • Tiia Voor,
  • Hiie Soeorg and ,
  • Merle Rätsep,
  • Reet Mändar,
  • Marika Mikelsaar and
  • Epp Sepp
  • + 3 authors+ 0 author

The aim of this study was to compare the human intestinal microbiota in different age groups, elucidating the precise stages of life in which the gut microbiota evolves its specific characteristics in terms of composition and diversity, as well as as...

  • Article
  • Open Access
1 Citations
1,234 Views
15 Pages

High-Intensity Interval Exercise Drives Vitamin D Receptor Expression in Skeletal Muscle via Recruitment of Non-Parenchymal Cells, Not Upregulation in Muscle Fibers

  • Kenneth Ladd Seldeen,
  • Ni Wang,
  • Rupadevi Muthaiah,
  • Owen Paul Treanor and ,
  • Anna Leigh Davis,
  • Lee Daniel Chaves,
  • Ramkumar Thiyagarajan,
  • Brandon J. Marzullo,
  • Donald Albert Yergeau and
  • Bruce Robert Troen
  • + 5 authors+ 0 author

28 November 2025

Background: High-intensity interval exercise (HIIE) is gaining interest as an alternative to traditional moderate-intensity exercise due to its shorter exercise regimens. Yet, it still induces significant muscular adaptations, including metabolic rem...

(This article belongs to the Section Micronutrients and Human Health)
  • Article
  • Open Access
16 Citations
4,478 Views
9 Pages

Effects of Acute High-Intensity Interval Exercise and High-Intensity Continuous Exercise on Inhibitory Function of Overweight and Obese Children

  • Ligong Zhang,
  • Dongshi Wang,
  • Siwen Liu,
  • Fei-Fei Ren and ,
  • Lin Chi and
  • Chun Xie
  • + 1 author+ 0 author

This study aimed to examine whether a single bout each of high-intensity interval exercise (HIIE) and high-intensity continuous exercise (HICE) could improve inhibitory functions of overweight and obese children, and which mode of exercise was more b...

(This article belongs to the Section Exercise and Health)
  • Article
  • Open Access
17 Citations
6,979 Views
11 Pages

16 April 2018

(1) Background: This study investigated the effect of acute barehanded whole body high-intensity intermittent exercise (HIIE) and moderate intensity and continuous exercise (MICE) at the same quantity of energy expenditure on postprandial triglycerid...

  • Article
  • Open Access
27 Citations
9,209 Views
11 Pages

Prolonged Post-Exercise Hypotension: Effects of Different Exercise Modalities and Training Statuses in Elderly Patients with Hypertension

  • Ferdinando Iellamo,
  • Giuseppe Caminiti,
  • Matteo Montano,
  • Vincenzo Manzi and ,
  • Alessio Franchini,
  • Annalisa Mancuso and
  • Maurizio Volterrani
  • + 2 authors+ 0 author

Background: In this study, we aimed at comparing the effects of three different exercise modalities on post-exercise hypotension (PEH) in elderly hypertensive patients and at investigating whether PEH responses to the same exercises are affected by t...

(This article belongs to the Special Issue Sport-Exercise and Stress: A Winning Combination)
  • Article
  • Open Access
19 Citations
4,209 Views
11 Pages

Comparison of the Sustainability Effects of High-Intensity Interval Exercise and Moderate-Intensity Continuous Exercise on Cognitive Flexibility

  • Shudong Tian,
  • Hong Mou,
  • Qun Fang,
  • Xiaoxiao Zhang and ,
  • Fanying Meng and
  • Fanghui Qiu
  • + 1 author+ 0 author

This study examined the immediate and sustained effects of high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE) on cognitive flexibility in young adults. Participants (n = 56) engaged in (1) a session of HIIE, inv...

  • Article
  • Open Access
18 Citations
3,766 Views
13 Pages

The Influence of an Acute Bout of Aerobic Exercise on Vascular Endothelial Function in Moderate Stages of Chronic Kidney Disease

  • Jeffrey S. Forsse,
  • Zacharias Papadakis,
  • Matthew N. Peterson,
  • James Kyle Taylor and ,
  • Burritt W. Hess,
  • Nicholas Schwedock,
  • Dale C. Allison,
  • Jackson O. Griggs,
  • Ronald L. Wilson and
  • Peter W. Grandjean
  • + 5 authors+ 0 author

9 January 2022

Chronic kidney disease (CKD) is directly influenced by the deleterious effects of systemic inflammation and oxidative stress. The vascular endothelium may transiently respond to aerobic exercise and improve post-exercise vascular renal function in mo...

(This article belongs to the Special Issue Endothelial Dysfunction and Cardiovascular Disease in Chronic Kidney Disease and Dialysis: A 2022 Update)
  • Article
  • Open Access
34 Citations
8,229 Views
14 Pages

Acute Effects of High-Intensity Interval and Moderate-Intensity Continuous Exercise on GLP-1, Appetite and Energy Intake in Obese Men: A Crossover Trial

  • Victor A. F. Matos,
  • Daniel C. Souza,
  • Victor O. A. Santos,
  • Ítalo F. Medeiros and ,
  • Rodrigo A. V. Browne,
  • Paulo R. P. Nascimento,
  • Cristiane S. R. Marinho,
  • Alexandre C. Serquiz,
  • Eduardo C. Costa and
  • Ana Paula Trussardi Fayh
  • + 5 authors+ 0 author

12 July 2018

This study investigated the effect of high-intensity interval (HIIE) and moderate-intensity continuous exercise (MICE) on glucagon-like peptide 1 (GLP-1), appetite and energy intake (EI) in obese men. In a randomized crossover trial, 12 participants...

(This article belongs to the Special Issue Appetite, Metabolism and Obesity)
  • Article
  • Open Access
54 Citations
12,278 Views
15 Pages

Accuracy of Continuous Glucose Monitoring (CGM) during Continuous and High-Intensity Interval Exercise in Patients with Type 1 Diabetes Mellitus

  • Othmar Moser,
  • Julia K. Mader,
  • Gerhard Tschakert,
  • Alexander Mueller and ,
  • Werner Groeschl,
  • Thomas R. Pieber,
  • Gerd Koehler,
  • Janin Messerschmidt and
  • Peter Hofmann
  • + 4 authors+ 0 author

10 August 2016

Continuous exercise (CON) and high-intensity interval exercise (HIIE) can be safely performed with type 1 diabetes mellitus (T1DM). Additionally, continuous glucose monitoring (CGM) systems may serve as a tool to reduce the risk of exercise-induced h...

  • Article
  • Open Access
31 Citations
8,119 Views
15 Pages

Effects of Different Exercise Modes on the Urinary Metabolic Fingerprint of Men with and without Metabolic Syndrome

  • Aikaterina Siopi,
  • Olga Deda,
  • Vasiliki Manou,
  • Spyros Kellis and ,
  • Ioannis Kosmidis,
  • Despina Komninou,
  • Nikolaos Raikos,
  • Kosmas Christoulas,
  • Georgios A. Theodoridis and
  • Vassilis Mougios
  • + 5 authors+ 0 author

26 January 2017

Exercise is important in the prevention and treatment of the metabolic syndrome (MetS), a cluster of risk factors that raises morbidity. Metabolomics can facilitate the optimization of exercise prescription. This study aimed to investigate whether th...

(This article belongs to the Special Issue Metabolomics 2016)
  • Article
  • Open Access
3 Citations
2,503 Views
13 Pages

Adults who have had an amputation face barriers to having an active lifestyle which attenuates cardiorespiratory fitness. Prior studies in amputees typically involve treadmill walking or arm ergometry, yet physiological responses to bilateral leg cyc...

(This article belongs to the Section Exercise and Health-Related Quality of Life)
  • Article
  • Open Access
3 Citations
2,954 Views
14 Pages

21 March 2024

High-intensity interval exercise (HIIE) is a type of structured physical training characterized by repeated bouts of high-intensity exercise interspersed with recovery periods. Although HIIE was found to improve physical performance in a relatively s...

(This article belongs to the Special Issue Exercise, Fitness, Human Performance and Health)
  • Article
  • Open Access
2 Citations
2,191 Views
9 Pages

The Effects of Acute Bouts of Aerobic Exercise on Adipokine Concentrations in Individuals with Moderate Stages of Chronic Kidney Disease

  • Tomas J. Chapman-Lopez,
  • James Kyle Taylor,
  • Ricardo Torres,
  • Dylan Wilburn and ,
  • LesLee K. Funderburk,
  • Dale C. Allison and
  • Jeffrey S. Forsse
  • + 2 authors+ 0 author

17 October 2023

This study examined the effects of two different acute bouts of treadmill running (e.g., steady-state moderate-intensity exercise (SSE) and high-intensity interval exercise (HIIE)) on adipokine (e.g., adiponectin, leptin, and omentin) concentrations...

(This article belongs to the Special Issue Exercise Physiology and Biochemistry)
  • Article
  • Open Access
20 Citations
12 Views

Background: Excessive production of free radicals caused by many types of exercise results in oxidative stress, which leads to muscle damage, fatigue, and impaired performance. Supplementation with royal jelly (RJ) or coenzyme Q10 (CoQ10) has been sh...

  • Article
  • Open Access
10 Citations
6,804 Views
14 Pages

Memory Modulation by Exercise in Young Adults Is Related to Lactate and Not Affected by Sex or BDNF Polymorphism

  • Juan Arturo Ballester-Ferrer,
  • Alba Roldan,
  • Eduardo Cervelló and
  • Diego Pastor

20 October 2022

Currently, high-intensity interval exercise (HIIE) is on the rise compared to moderate-intensity exercise (MIE) due to its similar benefits for health and performance with low time requirements. Recent studies show how physical exercise can also infl...

(This article belongs to the Special Issue New Frontiers of Sport, Exercise and Physical Activity for Health and Human Performance)
  • Article
  • Open Access
13 Citations

Background: Nutritional ergogenic aids are commonly used to boost physiological adaptations to exercise and promote greater fitness gains. However, there is a paucity of data about multi-ingredient pre-workout supplementation (MIPS). Therefore, the a...

  • Systematic Review
  • Open Access
1,239 Views
19 Pages

Synergy or Dominance? The Ergogenic Effects of Caffeine and Carbohydrate on High-Intensity Interval Exercise Performance: A Three-Level Meta-Analysis

  • Hao Li,
  • Yixiang Peng,
  • Baiyu Liu,
  • Li Ding and ,
  • Kai Xu,
  • Tze-Huan Lei,
  • Bomin Gong and
  • Yinhang Cao
  • + 3 authors+ 0 author

10 June 2026

Background/Objectives: This meta-analysis aimed to quantify the combined ergogenic effects of caffeine (CAF) and carbohydrate (CHO) on high-intensity interval exercise (HIIE) performance and to identify potential moderating factors. Methods: Four dat...

(This article belongs to the Special Issue Individualised Caffeine Use in Sport and Exercise)
  • Article
  • Open Access
4 Citations
3,469 Views
17 Pages

Although blood still remains the most commonly utilized medium to detect increased levels of oxidative damage induced by exercise, saliva diagnostics have gained increasing popularity due to their non-invasive nature and athlete-friendly collection p...

(This article belongs to the Topic Oxidative Stress and Inflammation, 2nd Volume)
  • Article
  • Open Access
6 Citations
3,122 Views
10 Pages

The Impact of Obesity on C1q/TNF-Related Protein-9 Expression and Endothelial Function following Acute High-Intensity Interval Exercise vs. Continuous Moderate-Intensity Exercise

  • Brandon G. Fico,
  • Ryan S. Garten,
  • Michael C. Zourdos,
  • Michael Whitehurst and ,
  • Peter J. Ferrandi,
  • Katelyn M. Dodge,
  • Gabriel S. Pena,
  • Alexandra A. Rodriguez and
  • Chun-Jung Huang
  • + 4 authors+ 0 author

15 November 2022

C1q-TNF-related protein-9 (CTRP9) increases endothelial nitric oxide synthase and reduces vasoconstrictors. There is limited information regarding exercise-mediated CTRP9 in obesity. The purpose of this study was to compare high-intensity interval ex...

(This article belongs to the Section Physiology)
  • Article
  • Open Access
10 Citations
4,775 Views
12 Pages

1 December 2023

The current investigation compared the acute oxygen consumption (VO2) response of two high-intensity interval exercises (HIIE), fast start (FSHIIE), and steady power (SPHIIE), which matched w prime (W’) depletion. Eight cyclists completed an in...

  • Article
  • Open Access
11 Citations
11,700 Views
13 Pages

Short-Time β-Alanine Supplementation on the Acute Strength Performance after High-Intensity Intermittent Exercise in Recreationally Trained Men

  • Marcelo Conrado Freitas,
  • Jason Cholewa,
  • Valéria Panissa,
  • Giovanni Quizzini and ,
  • João Vitor de Oliveira,
  • Caique Figueiredo,
  • Luis Alberto Gobbo,
  • Erico Caperuto,
  • Nelo Eidy Zanchi and
  • Fabrício Eduardo Rossi
  • + 6 authors+ 1 author

9 May 2019

(1) Background: We investigated the effects of 28 days of beta-alanine (β-alanine) supplementation on the acute interference effect of high-intensity intermittent exercise (HIIE) on lower-body resistance exercise performance, body composition, a...

(This article belongs to the Special Issue Optimising Interval Training Prescription)
  • Article
  • Open Access
8 Citations
5,415 Views
12 Pages

The Effects of High-Intensity Interval Exercise on Skeletal Muscle and Cerebral Oxygenation during Cycling and Isokinetic Concentric and Eccentric Exercise

  • Panagiotis A. Perentis,
  • Evgenia D. Cherouveim,
  • Vassiliki J. Malliou,
  • Nikos V. Margaritelis and ,
  • Panagiotis N. Chatzinikolaou,
  • Panayiotis Koulouvaris,
  • Charilaos Tsolakis,
  • Michalis G. Nikolaidis,
  • Nickos D. Geladas and
  • Vassilis Paschalis
  • + 5 authors+ 0 author

The aim of the present study was to study the effects of cycling and pure concentric and pure eccentric high-intensity interval exercise (HIIE) on skeletal muscle (i.e., vastus lateralis) and cerebral oxygenation. Twelve healthy males (n = 12, age 26...

(This article belongs to the Special Issue Applied Sport Physiology and Performance—2nd Edition)
  • Article
  • Open Access
709 Views
14 Pages

Acute and Chronic High-Intensity Exercise Differentially Regulate the miRNA Biogenesis Pathway in Human Skeletal Muscle

  • Zeyu Wu,
  • Eveline S. Menezes,
  • Natalia de M. Lyra e Silva,
  • Benjamin B. Arhen and ,
  • Lucas P. R. Beaupre,
  • Craig A. Simpson,
  • Chris McGlory,
  • Fernanda G. De Felice and
  • Brendon J. Gurd
  • + 4 authors+ 0 author

29 May 2026

Background/Objectives: MicroRNAs (miRNAs) are key regulators of skeletal muscle adaptation; however, the extent to which exercise modulates the miRNA biogenesis pathway remains poorly understood. To investigate the impact of acute and chronic high-in...

(This article belongs to the Section RNA)
  • Article
  • Open Access
10 Citations
3,202 Views
15 Pages

The purpose of this study was to examine if low-volume, high-intensity interval exercise (HIIE) was associated with changes in 24-h movement behaviors. A quasi-experimental study design was used. We collected accelerometry data from 21 eligible parti...

(This article belongs to the Special Issue Physical and Sport Activity for Wellbeing, Lifestyle, Health Promotion and Chronic Diseases Prevention)
  • Article
  • Open Access
21 Citations
5,129 Views
17 Pages

Comparison of the Serum Metabolic Fingerprint of Different Exercise Modes in Men with and without Metabolic Syndrome

  • Aikaterina Siopi,
  • Olga Deda,
  • Vasiliki Manou,
  • Ioannis Kosmidis and ,
  • Despina Komninou,
  • Nikolaos Raikos,
  • Georgios A. Theodoridis and
  • Vassilis Mougios
  • + 3 authors+ 0 author

Exercise plays a beneficial role in the treatment of metabolic syndrome (MetS). Metabolomics can provide new insights and facilitate the optimization of exercise prescription. This study aimed to investigate whether the response of the human serum me...

(This article belongs to the Special Issue Exercise Metabonomics)
  • Article
  • Open Access
5 Citations
5,485 Views
14 Pages

Acute Low-Dose Hyperoxia during a Single Bout of High-Intensity Interval Exercise Does Not Affect Red Blood Cell Deformability and Muscle Oxygenation in Trained Men—A Randomized Crossover Study

  • Nils Freitag,
  • Tim Böttrich,
  • Pia D. Weber,
  • Giorgio Manferdelli and ,
  • Daniel A. Bizjak,
  • Marijke Grau,
  • Tanja C. Sanders,
  • Wilhelm Bloch and
  • Moritz Schumann
  • + 4 authors+ 0 author

4 January 2020

Recent technological developments provide easy access to use an artificial oxygen supply (hyperoxia) during exercise training. The aim of this study was to assess the efficacy of a commercially available oxygen compressor inducing low-dose hyperoxia,...

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