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109 Results Found

  • Article
  • Open Access
2 Citations
2,717 Views
14 Pages

8 December 2023

This paper discusses the application of a new honeycomb FCH HVAC (Free Cooling and Heating System, Heating, Ventilation, and Air Conditioning) ring network technology that reduces the primary energy consumption in existing infrastructure. The aim of...

(This article belongs to the Special Issue Advanced Technologies in HVAC Equipment and Thermal Environment for Building)
  • Article
  • Open Access
7 Citations
7,225 Views
16 Pages

Familial Combined Hyperlipidemia (FCH) Patients with High Triglyceride Levels Present with Worse Lipoprotein Function Than FCH Patients with Isolated Hypercholesterolemia

  • Núria Puig,
  • Inka Miñambres,
  • Sonia Benítez,
  • Pedro Gil and ,
  • Margarida Grau-Agramunt,
  • Andrea Rivas-Urbina,
  • Antonio Pérez and
  • José Luis Sánchez-Quesada
  • + 3 authors+ 0 author

Lipoprotein characteristics were analyzed in familial combined hyperlipidemia (FCH) patients before and after statin treatment. Twenty-six FCH patients were classified according to the presence (HTG group, n = 13) or absence (normotriglyceridemic (NT...

(This article belongs to the Special Issue High-Density Lipoproteins and Cardiovascular Disease: The Good, the Bad, and the Future)
  • Review
  • Open Access
1 Citations
3,191 Views
16 Pages

Bench to Bedside Development of [18F]Fluoromethyl-(1,2-2H4)choline ([18F]D4-FCH)

  • Amarnath Challapalli,
  • Tara D. Barwick,
  • Suraiya R. Dubash,
  • Marianna Inglese and ,
  • Matthew Grech-Sollars,
  • Kasia Kozlowski,
  • Henry Tam,
  • Neva H. Patel,
  • Mathias Winkler and
  • Stephen Mangar
  • + 11 authors+ 6 authors

8 December 2023

Malignant transformation is characterised by aberrant phospholipid metabolism of cancers, associated with the upregulation of choline kinase alpha (CHKα). Due to the metabolic instability of choline radiotracers and the increasing use of late-i...

(This article belongs to the Special Issue Radiopharmaceuticals)
  • Article
  • Open Access
9 Citations
2,605 Views
15 Pages

Multitracer PET/CT with [18F]Fluorodeoxiglucose and [18F]Fluorocholine in the Initial Staging of Multiple Myeloma Patients Applying the IMPeTus Criteria: A Pilot Study

  • Puy Garrastachu Zumarán,
  • Irene García Megías,
  • María Mangas Losada,
  • Alejandro Mendoza Melero and ,
  • Amós Villanueva Torres,
  • Xavier Boulvard Chollet,
  • Leonardo Romero Robles,
  • Prisma Montserrat Hernández Pérez,
  • Rafael Ramírez Lasanta and
  • Roberto C. Delgado Bolton
  • + 5 authors+ 0 author

Initial staging of patients diagnosed with multiple myeloma (MM) can lead to negative results using conventional diagnostic imaging workup, including [18F]Fluorodesoxiglucose ([18F]FDG) PET/CT. The aim of this prospective pilot study was to evaluate...

(This article belongs to the Special Issue Advances in PET/CT Imaging)
  • Article
  • Open Access
14 Citations
4,956 Views
14 Pages

Fatty Liver as Potential Biomarker of Atherosclerotic Damage in Familial Combined Hyperlipidemia

  • Giuseppe Mandraffino,
  • Carmela Morace,
  • Maria Stella Franzè,
  • Veronica Nassisi and ,
  • Davide Sinicropi,
  • Maria Cinquegrani,
  • Carlo Saitta,
  • Riccardo Scoglio,
  • Sebastiano Marino and
  • Giovanni Squadrito
  • + 10 authors+ 5 authors

Familial combined hyperlipidemia (FCH) is a very common inherited lipid disorder, characterized by a high risk of developing cardiovascular (CV) disease and metabolic complications, including insulin resistance (IR) and type 2 diabetes mellitus (T2DM...

(This article belongs to the Special Issue Metabolic and Genetic Associated Fatty Liver Diseases)
  • Review
  • Open Access
12 Citations
4,832 Views
13 Pages

Primary Hyperparathyroidism: 18F-Fluorocholine PET/CT vs. 4D-CT for Parathyroid Identification: Toward a Comprehensive Diagnostic Framework—An Updated Review and Recommendations

  • Gregorio Scerrino,
  • Nunzia Cinzia Paladino,
  • Giuseppa Graceffa,
  • Giuseppina Melfa and ,
  • Giuseppina Orlando,
  • Renato Di Vuolo,
  • Chiara Lo Cicero,
  • Alessandra Murabito,
  • Stefano Radellini and
  • Antonio Lo Casto
  • + 6 authors+ 1 author

4 August 2025

Introduction: Primary hyperparathyroidism (pHPT) is an endocrine disorder characterized by excessive parathyroid hormone production, typically due to adenomas, hyperplasia, or carcinoma. Preoperative imaging plays a critical role in guiding surgical...

(This article belongs to the Section General Surgery)
  • Article
  • Open Access
5 Citations
2,095 Views
13 Pages

27 June 2022

It is now highly likely that with the rise in fuel, gas and electricity prices, groundwater deposits will become the third primary source of renewable energy, alongside photovoltaic cells and wind turbines. These deposits are characterized by unlimit...

(This article belongs to the Section G: Energy and Buildings)
  • Article
  • Open Access
83 Citations
5,752 Views
31 Pages

Hybrid and Deep Learning Approach for Early Diagnosis of Lower Gastrointestinal Diseases

  • Suliman Mohamed Fati,
  • Ebrahim Mohammed Senan and
  • Ahmad Taher Azar

27 May 2022

Every year, nearly two million people die as a result of gastrointestinal (GI) disorders. Lower gastrointestinal tract tumors are one of the leading causes of death worldwide. Thus, early detection of the type of tumor is of great importance in the s...

(This article belongs to the Special Issue Deep Learning for Pathology Detection and Diagnosis in Medical Imaging)
  • Article
  • Open Access
84 Citations
5,227 Views
23 Pages

Oral squamous cell carcinoma (OSCC) is one of the most common head and neck cancer types, which is ranked the seventh most common cancer. As OSCC is a histological tumor, histopathological images are the gold diagnosis standard. However, such diagnos...

(This article belongs to the Special Issue Lesion Detection and Analysis Using Artificial Intelligence)
  • Article
  • Open Access
38 Citations
3,612 Views
23 Pages

Hybrid Techniques for Diagnosis with WSIs for Early Detection of Cervical Cancer Based on Fusion Features

  • Badiea Abdulkarem Mohammed,
  • Ebrahim Mohammed Senan,
  • Zeyad Ghaleb Al-Mekhlafi,
  • Meshari Alazmi and ,
  • Abdulaziz M. Alayba,
  • Adwan Alownie Alanazi,
  • Abdulrahman Alreshidi and
  • Mona Alshahrani
  • + 3 authors+ 0 author

2 September 2022

Cervical cancer is a global health problem that threatens the lives of women. Liquid-based cytology (LBC) is one of the most used techniques for diagnosing cervical cancer; converting from vitreous slides to whole-slide images (WSIs) allows images to...

(This article belongs to the Section Computing and Artificial Intelligence)
  • Article
  • Open Access
22 Citations
4,174 Views
22 Pages

Diagnosis of Histopathological Images to Distinguish Types of Malignant Lymphomas Using Hybrid Techniques Based on Fusion Features

  • Zeyad Ghaleb Al-Mekhlafi,
  • Ebrahim Mohammed Senan,
  • Badiea Abdulkarem Mohammed,
  • Meshari Alazmi and ,
  • Abdulaziz M. Alayba,
  • Abdulrahman Alreshidi and
  • Mona Alshahrani
  • + 2 authors+ 0 author

10 September 2022

Malignant lymphoma is one of the types of malignant tumors that can lead to death. The diagnostic method for identifying malignant lymphoma is a histopathological analysis of lymphoma tissue images. Because of the similar morphological characteristic...

  • Article
  • Open Access
44 Citations
4,479 Views
24 Pages

Multi-Method Diagnosis of Histopathological Images for Early Detection of Breast Cancer Based on Hybrid and Deep Learning

  • Mohammed Al-Jabbar,
  • Mohammed Alshahrani,
  • Ebrahim Mohammed Senan and
  • Ibrahim Abdulrab Ahmed

15 March 2023

Breast cancer (BC) is a type of cancer suffered by adult females worldwide. A late diagnosis of BC leads to death, so early diagnosis is essential for saving lives. There are many methods of diagnosing BC, including surgical open biopsy (SOB), which...

(This article belongs to the Special Issue Mathematical Modelling and Machine Learning Methods for Bioinformatics and Data Science Applications, 2nd Edition)
  • Article
  • Open Access
11 Citations
3,777 Views
24 Pages

30 September 2024

Forest canopy height (FCH) is an important variable for estimating forest biomass and ecosystem carbon sequestration. Spaceborne LiDAR data have been used to create wall-to-wall FCH maps, such as the forest tree height map of China (FCHChina), Global...

(This article belongs to the Special Issue Lidar for Forest Parameters Retrieval)
  • Article
  • Open Access
2 Citations
914 Views
23 Pages

Assessment of Three High-Resolution Forest Canopy Height Products in China

  • Yue Cao,
  • Jie Ma,
  • Ran Wang,
  • Chunhua Zhang and ,
  • Di Zhou,
  • Haoran Man and
  • Dan Lu
  • + 2 authors+ 0 author

31 March 2026

Large-scale mapping of forest canopy height (FCH) is crucial for accurately understanding ecosystem succession and forest carbon sinks. Recently, three high-resolution FCH products have been released, including global forest canopy height (GFCH), NNG...

(This article belongs to the Special Issue Advanced Remote Sensing Technology for Precision Forestry and Carbon Sink Assessment)
  • Article
  • Open Access
13 Citations
9,011 Views
11 Pages

Chronic Liver Disease and the Detection of Hepatocellular Carcinoma by [18F]fluorocholine PET/CT

  • Sandi A. Kwee,
  • Linda L. Wong,
  • Brenda Y. Hernandez,
  • Owen T.M. Chan and ,
  • Miles M. Sato and
  • Naoky Tsai
  • + 1 author+ 0 author

Positron emission tomography (PET) using the radiopharmaceutical tracer fluorine-18 fluorocholine (FCh) can elucidate tumors based on differences in choline phospholipid metabolism between tumor and surrounding tissue. The feasibility of detecting he...

(This article belongs to the Special Issue Diagnosis of Hepatocellular Carcinoma)
  • Article
  • Open Access
4 Citations
2,930 Views
16 Pages

Human Serum, Following Absorption of Fish Cartilage Hydrolysate, Promotes Dermal Fibroblast Healing through Anti-Inflammatory and Immunomodulatory Proteins

  • Julie Le Faouder,
  • Aurélie Guého,
  • Régis Lavigne,
  • Fabien Wauquier and ,
  • Line Boutin-Wittrant,
  • Elodie Bouvret,
  • Emmanuelle Com,
  • Yohann Wittrant and
  • Charles Pineau
  • + 4 authors+ 0 author

19 September 2024

Background/Objectives: Marine collagen peptides (MCPs) and glycosaminoglycans (GAGs) have been described as potential wound-healing (WH) agents. Fish cartilage hydrolysate (FCH) is a natural active food ingredient obtained from enzymatic hydrolysis w...

(This article belongs to the Section Cell Biology and Pathology)
  • Article
  • Open Access
5 Citations
1,880 Views
25 Pages

A Novel Workflow for Mapping Forest Canopy Height by Synergizing ICESat-2 and Multi-Sensor Data

  • Linghui Guo,
  • Yang Zhang,
  • Muchao Xu,
  • Jingjing Yan and ,
  • Hebing Zhang,
  • Youfeng Zou and
  • Jiangbo Gao
  • + 2 authors+ 0 author

4 December 2024

Precise information on forest canopy height (FCH) is critical for forest carbon stocks estimation and management, but mapping continuous FCH with satellite data at regional scale is still a challenge. By fusing ICESat-2, Sentinel-1/2 images and ancil...

(This article belongs to the Section Forest Inventory, Modeling and Remote Sensing)
  • Article
  • Open Access
7 Citations
2,217 Views
14 Pages

23 October 2025

The present study investigated the effects of fermented Chinese herbal (FCH) compounds on the egg production, egg shell quality, and egg yolk cholesterol of laying hens. A total of 1260 Hy-Line pink laying hens, 34 weeks old, were randomly divided in...

(This article belongs to the Section Animal Nutrition)
  • Article
  • Open Access
2 Citations
1,173 Views
12 Pages

Increased CX3CL1/CX3CR1 Axis Is Related to Atherosclerosis in Subjects with Familial Combined Hyperlipidaemia, Which Is Modulated by Insulin Resistance but Not by Sex

  • Elena Jiménez-Martí,
  • Clara Espinosa-Bellido,
  • Blanca Alabadi,
  • Gema Hurtado-Genovés and ,
  • Antonio Enrique-Medina,
  • Susana Martín-Vañó,
  • Víctor Casas,
  • Eduardo A. Cortés Nadal,
  • José T. Real and
  • Sergio Martínez-Hervás
  • + 6 authors+ 1 author

28 September 2025

Background: A major factor in the development of atherosclerosis is the presence of a chronic inflammatory state. The CX3CL1/CX3CR1 axis has been implicated in the development of atherosclerosis and cardiovascular disease, but until now, scarce data...

(This article belongs to the Section Endocrinology and Metabolism Research)
  • Review
  • Open Access
5 Citations
3,643 Views
13 Pages

28 February 2023

Indeterminate thyroid nodules (ITN) are commonly encountered among the general population, with a malignancy rate of 10 to 40%. However, many patients may be overtreated with futile surgery for benign ITN. To avoid unnecessary surgery, PET/CT scan is...

(This article belongs to the Special Issue PET/CT in Head and Neck Cancer)
  • Article
  • Open Access
85 Citations
6,876 Views
25 Pages

Histopathological Analysis for Detecting Lung and Colon Cancer Malignancies Using Hybrid Systems with Fused Features

  • Mohammed Al-Jabbar,
  • Mohammed Alshahrani,
  • Ebrahim Mohammed Senan and
  • Ibrahim Abdulrab Ahmed

Lung and colon cancer are among humanity’s most common and deadly cancers. In 2020, there were 4.19 million people diagnosed with lung and colon cancer, and more than 2.7 million died worldwide. Some people develop lung and colon cancer simulta...

(This article belongs to the Special Issue Machine Learning and Artificial Intelligence for Biomedical Applications)
  • Review
  • Open Access
32 Citations
6,914 Views
21 Pages

Diagnostic Value of Choline PET in the Preoperative Localization of Hyperfunctioning Parathyroid Gland(s): A Comprehensive Overview

  • Cristina Ferrari,
  • Giulia Santo,
  • Paolo Mammucci,
  • Antonio Rosario Pisani and ,
  • Angela Sardaro and
  • Giuseppe Rubini
  • + 1 author+ 0 author

Hyperparathyroidism is a metabolic disorder characterized by the excessive production of the parathyroid hormone. The diagnosis is based on clinical and laboratory data. In most cases the only treatment is surgery and a correct preoperatory localizat...

(This article belongs to the Section Molecular and Translational Medicine)
  • Article
  • Open Access
10 Citations
2,894 Views
12 Pages

[18F]fluoro-ethylcholine-PET Plus 4D-CT (FEC-PET-CT): A Break-Through Tool to Localize the “Negative” Parathyroid Adenoma. One Year Follow Up Results Involving 170 Patients

  • Constantin Smaxwil,
  • Philip Aschoff,
  • Gerald Reischl,
  • Mirjam Busch and ,
  • Joachim Wagner,
  • Julia Altmeier,
  • Oswald Ploner and
  • Andreas Zielke
  • + 3 authors+ 0 author

13 April 2021

Background: The diagnostic performance of [18F]fluoro-ethylcholine-PET-CT&4D-CT (FEC-PET&4D-CT) to identify parathyroid adenomas (PA) was analyzed when ultrasound (US) or MIBI-Scan (MS) failed to localize. Postsurgical one year follow-up data...

(This article belongs to the Special Issue Novel Methods of Diagnostics of Thyroid and Parathyroid Lesions)
  • Article
  • Open Access
1 Citations
2,044 Views
31 Pages

Accurate Estimation of Forest Canopy Height Based on GEDI Transmitted Deconvolution Waveforms

  • Longtao Cai,
  • Jun Wu,
  • Inthasone Somsack,
  • Xuemei Zhao and
  • Jiasheng He

11 October 2025

Accurate estimation of the forest canopy height is crucial in monitoring the global carbon cycle and evaluating progress toward carbon neutrality goals. The Global Ecosystem Dynamics Investigation (GEDI) mission provides an important data source for...

(This article belongs to the Collection Feature Paper Special Issue on Forest Remote Sensing)
  • Article
  • Open Access
1 Citations
2,251 Views
17 Pages

26 November 2024

The article investigates HVAC (heating, ventilation, and air conditioning) technologies aimed at mitigating Primary Energy (PE) consumption in renovated buildings. This research is part of a broader initiative focused on enhancing air quality and red...

(This article belongs to the Special Issue Thermal Environment and Energy Saving in Buildings)
  • Article
  • Open Access
16 Citations
2,568 Views
17 Pages

Anti-Fatigue Activity of Corn Protein Hydrolysate Fermented by Lactic Acid Bacteria

  • Nan Hu,
  • Jingyi Sun,
  • Yujia Cao,
  • Hongji Zhao and ,
  • Meng Sun,
  • Guanlong Li,
  • Xiaolan Liu and
  • Shanzi Cong
  • + 3 authors+ 0 author

7 January 2025

Objectives: This study aimed to clarify the effect of lactic acid bacteria-fermented corn protein hydrolysate (FCH) on fatigue in mice and explore the connection between fatigue-related indicators and intestinal microbial flora. Methods: The fatigue...

(This article belongs to the Special Issue Nutrition and Quality of Life for Patients with Chronic Disease)
  • Article
  • Open Access
29 Citations
5,998 Views
11 Pages

Introduction: To examine the validity and reliability of the Fitbit Charge HR (FCH), wrist-worn ActiGraph (AG) accelerometers were used for assessing the classification of physical activity (PA) into intensity categories in children. Methods: Forty-t...

(This article belongs to the Special Issue Health Promotion: Physical Activity and Nutrition Behaviors in Children and Youth)
  • Interesting Images
  • Open Access
1 Citations
3,468 Views
3 Pages

An Incidental Pancreatic Finding at 18F-Choline PET/CT: Chronic Mass-Forming Pancreatitis

  • Laura Evangelista,
  • Alessandro De Pellegrin,
  • Rossano Girometti,
  • Gianluca Cassarino and ,
  • Francesco Giacomuzzi and
  • Marco Rensi
  • + 1 author+ 0 author

We present a case of a chronic mass-forming pancreatitis (CMFP) detected by 18F-choline (FCH) PET/CT in a male affected by prostate cancer. FCH PET/CT scan showed a focal uptake in the uncinate process of the pancreas, later diagnosed as a CMFP at bi...

(This article belongs to the Collection Interesting Images)
  • Article
  • Open Access
6 Citations
3,612 Views
18 Pages

Consideration of Metabolite Efflux in Radiolabelled Choline Kinetics

  • Yunqing Li,
  • Marianna Inglese,
  • Suraiya Dubash,
  • Chris Barnes and ,
  • Diana Brickute,
  • Marta Costa Braga,
  • Ning Wang,
  • Alice Beckley,
  • Kathrin Heinzmann and
  • Eric O. Aboagye
  • + 10 authors+ 5 authors

Hypoxia is a complex microenvironmental condition known to regulate choline kinase α (CHKA) activity and choline transport through transcription factor hypoxia-inducible factor-1α (HIF-1α) and, therefore, may confound the uptake of choline radiotrace...

(This article belongs to the Special Issue Choline kinase, a Target with Broad-Spectrum Therapeutic Potential: Opportunities and Challenges)
  • Article
  • Open Access
8 Citations
2,228 Views
21 Pages

11 January 2025

Forest canopy height (FCH) is a critical parameter for forest management and ecosystem modeling, but there is a lack of accurate FCH distribution in large areas. To address this issue, this study selected Wuyishan National Park in China as a case stu...

(This article belongs to the Special Issue Mapping and Modeling Forests Using Geospatial Technologies)
  • Article
  • Open Access
141 Views
31 Pages

27 October 2026

Forest canopy height (FCH) is a key parameter for estimating forest aboveground biomass (AGB) and carbon storage. The integration of GEDI relative height products and single-angle imagery has been widely applied in FCH estimation. However, GEDI geolo...

(This article belongs to the Special Issue Remote Sensing of Forest Structural Parameters and Aboveground Biomass)
  • Article
  • Open Access
6 Citations
2,908 Views
14 Pages

18F-Fluorocholine PET/CT Compared with Current Imaging Procedures for Preoperative Localization of Hyperfunctioning Parathyroids in Patients with Chronic Kidney Disease

  • Samuel Aymard,
  • Benjamin Leroy-Freschini,
  • Ashjan Kaseb,
  • David Marx and ,
  • Mehdi Helali,
  • Gerlinde Averous,
  • Valérie Betz,
  • Sophie Riehm,
  • Michel Vix and
  • Alessio Imperiale
  • + 6 authors+ 1 author

Hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) includes secondary (sHPT) and tertiary hyperparathyroidism (tHPT). Considering that the role of preoperative imaging in the clinical setting is controversial, in the present stud...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1,474 Views
17 Pages

7 August 2025

Background/Objectives: This study aims to evaluate the additional value of [18F]F-fluorocholine ([18F]F-FCH) PET/CT over contrast-enhanced magnetic resonance imaging (CE-MRI) in detecting the recurrence of brain metastases (BMs) after stereotactic ra...

(This article belongs to the Section Cancer Metastasis)
  • Article
  • Open Access
44 Citations
9,107 Views
26 Pages

Variational Models of Network Formation and Ion Transport: Applications to Perfluorosulfonate Ionomer Membranes

  • Nir Gavish,
  • Jaylan Jones,
  • Zhengfu Xu,
  • Andrew Christlieb and
  • Keith Promislow

24 February 2012

We present the functionalized Cahn-Hilliard (FCH) energy, a continuum characterization of interfacial energy whose minimizers describe the network morphology of solvated functionalized polymer membranes. With a small set of parameters the FCH charact...

  • Article
  • Open Access
11 Citations
2,608 Views
12 Pages

Evolving Role of [18F]Flurocholine PET/CT in Assessing Primary Hyperparathyroidism: Can It Be Considered the First-Line Functional Imaging Approach?

  • Seyedeh Sara Seyedinia,
  • Seyed Ali Mirshahvalad,
  • Gregor Schweighofer-Zwink,
  • Lukas Hehenwarter and ,
  • Gundula Rendl,
  • Christian Pirich and
  • Mohsen Beheshti
  • + 2 authors+ 0 author

19 January 2023

The accurate detection of hyperfunctioning parathyroid tissue (HFPT) is pivotal in the preoperative assessment of primary hyperparathyroidism (PHPT). PET/CT using [18F]fluorocholine ([18F]FCH) showed superior diagnostic performance compared to conven...

(This article belongs to the Section Endocrinology & Metabolism)
  • Article
  • Open Access
7 Citations
3,772 Views
16 Pages

Oral Iron Absorption of Ferric Citrate Hydrate and Hepcidin-25 in Hemodialysis Patients: A Prospective, Multicenter, Observational Riona-Oral Iron Absorption Trial

  • Naohisa Tomosugi,
  • Yoshitaka Koshino,
  • Chie Ogawa,
  • Kunimi Maeda and ,
  • Noriaki Shimada,
  • Kimio Tomita,
  • Shoichiro Daimon,
  • Tsutomu Shikano,
  • Kazuyuki Ryu and
  • Sayuri Shirai
  • + 41 authors+ 36 authors

7 September 2023

Oral ferric citrate hydrate (FCH) is effective for iron deficiencies in hemodialysis patients; however, how iron balance in the body affects iron absorption in the intestinal tract remains unclear. This prospective observational study (Riona-Oral Iro...

(This article belongs to the Special Issue Recent Advance on Iron Metabolism, Ferritin and Hepcidin Research 2.0)
  • Article
  • Open Access
8 Citations
3,812 Views
12 Pages

Bone metastases are common in prostate cancer (PCa). Fluorocholine-18 (FCH) and sodium fluoride-18 (NaF) have been used to assess PCa associated skeletal disease in thousands of patients by demonstrating different mechanism of uptake-cell membrane (l...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
12 Citations
3,561 Views
16 Pages

Comparison of Hormone-Sensitive Oligorecurrent Prostate Cancer Patients Based on Routine Use of Choline and/or PSMA PET/CT to Guide Metastasis-Directed Therapy

  • Raphaël Metz,
  • Aurore Rauscher,
  • Loïg Vaugier,
  • Stéphane Supiot and ,
  • Franck Drouet,
  • Loic Campion and
  • Caroline Rousseau
  • + 2 authors+ 0 author

22 March 2023

Background: In hormone-sensitive oligorecurrent prostate cancer (PC), the literature showed [68Ga]Ga-PSMA (PSMA) and [18F]F-choline (FCH) PET/CT can successfully guide metastasis-directed therapies (MDT). This observational retrospective study aimed...

(This article belongs to the Special Issue Prostate-Specific Membrane Antigen (PSMA))
  • Article
  • Open Access
11 Citations
4,092 Views
16 Pages

PET/CT with 18F-choline or 18F-FDG in Hepatocellular Carcinoma Submitted to 90Y-TARE: A Real-World Study

  • Luca Filippi,
  • Oreste Bagni,
  • Ermanno Notarianni,
  • Adelchi Saltarelli and ,
  • Cesare Ambrogi and
  • Orazio Schillaci
  • + 1 author+ 0 author

21 November 2022

Our aim was to assess the role of positron emission computed tomography (PET/CT) with 18F-choline (18F-FCH) or 18F-fluorodeoxyglucose (18F-FDG) in hepatocellular carcinoma (HCC) submitted to 90Y-radioembolization (90Y-TARE). We retrospectively analyz...

(This article belongs to the Section Cancer Biology and Oncology)
  • Article
  • Open Access
478 Views
18 Pages

The Diagnostic Accuracy of [18F]Fluorocholine PET/CT for the Preoperative Localization of Hyperfunctioning Parathyroid Glands

  • Chiara Lauri,
  • Giuseppe Campagna,
  • Lorenzo Chiurchioni,
  • Luciano Carideo and ,
  • Michela Varani,
  • Valeria Bentivoglio,
  • Anna Giorgio,
  • Francesco D’Angelo and
  • Alberto Signore
  • + 4 authors+ 0 author

12 September 2026

Background/Objectives: The purpose of this study was to compare [18F]Fluorocholine (FCH) PET/CT, ultrasound (US) and dual-phase scintigraphy with [99mTc]Tc-methoxyisobutylisonitrile (MIBI) and [99mTc]Tc-pertechnetate (TcO4-) ([99mTc]Tc-MIBI/[99mTc]Tc...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
8 Citations
3,232 Views
11 Pages

Feasibility of 18F-Fluorocholine PET for Evaluating Skeletal Muscle Atrophy in a Starved Rat Model

  • Sun Mi Park,
  • Jisu Kim,
  • Suji Baek,
  • Joo-Yeong Jeon and ,
  • Sang Ju Lee,
  • Seo Young Kang,
  • Min Young Yoo,
  • Hai-Jeon Yoon,
  • Seung Hae Kwon and
  • Byung Seok Moon
  • + 9 authors+ 4 authors

Imaging techniques for diagnosing muscle atrophy and sarcopenia remain insufficient, although various advanced diagnostic methods have been established. We explored the feasibility of 18F-fluorocholine (18F-FCH) positron emission tomography/computed...

(This article belongs to the Special Issue Advance in the Diagnostics and Management of Musculoskeletal Diseases)
  • Article
  • Open Access
432 Views
23 Pages

Dual-Rotary Trepanning of High-Quality Film Cooling Holes in DD6 Superalloy Using a Nanosecond Fiber Laser

  • Shichao Chang,
  • Mengqi Suo,
  • Chaowei Sun,
  • Anbo Hu and ,
  • Kang Li,
  • Jichao Yang,
  • Danyi Zhang,
  • Fazhan Tao,
  • Tianqing Jia and
  • Hongxing Xu
  • + 5 authors+ 0 author

15 August 2026

High-quality and high-efficiency machining of film cooling holes (FCHs) is critical for enhancing the performance of gas turbines and aero-engines. Nanosecond fiber lasers offer advantages such as high stability, good beam quality, and ease of integr...

  • Article
  • Open Access
8 Citations
4,566 Views
12 Pages

Preoperative Imaging with [18F]-Fluorocholine PET/CT in Primary Hyperparathyroidism

  • Franziska J. Dekorsy,
  • Leonie Beyer,
  • Christine Spitzweg,
  • Ralf Schmidmaier and ,
  • Andrei Todica,
  • Arnold Trupka,
  • Clemens C. Cyran,
  • Frank Berger,
  • Roland Ladurner and
  • Vera Wenter
  • + 9 authors+ 4 authors

23 May 2022

Primary hyperparathyroidism (pHPT) is a common endocrine disorder due to hyperfunctioning parathyroid glands. To date, the only curing therapy is surgical removal of the dysfunctional gland, making correct detection and localization crucial in order...

(This article belongs to the Section Nuclear Medicine & Radiology)
  • Article
  • Open Access
11 Citations
3,992 Views
18 Pages

Fermented Chinese Herbs Improve the Growth and Immunity of Growing Pigs through Regulating Colon Microbiota and Metabolites

  • Junhao Zhang,
  • Zhiheng Shu,
  • Sixiao Lv,
  • Qingwen Zhou and ,
  • Yuanhao Huang,
  • Yingjie Peng,
  • Jun Zheng,
  • Yi Zhou,
  • Chao Hu and
  • Shile Lan
  • + 5 authors+ 0 author

15 December 2023

(1) Background: the development of new antibiotic substitutes to promote pig growth and health has become an important way to solve the current dilemma and promote the pig industry. (2) Methods: to assess the effects of a fermented Chinese herbal (FC...

(This article belongs to the Section Animal Nutrition)
  • Article
  • Open Access
21 Citations
4,406 Views
12 Pages

18F-Fluorocholine PET and 4D-CT in Patients with Persistent and Recurrent Primary Hyperparathyroidism

  • Adrien Latge,
  • Sophie Riehm,
  • Michel Vix,
  • Jacob Bani and ,
  • Mihaela Ignat,
  • Valentin Pretet,
  • Mehdi Helali,
  • Giorgio Treglia and
  • Alessio Imperiale
  • + 4 authors+ 0 author

17 December 2021

Patients with primary hyperparathyroidism (pHPT) can develop persistent (P-pHPT) or recurrent (R-pHPT) disease after parathyroidectomy. Before recommending reoperation, recurrence must be accurately identified because of the high risk of complication...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1 Citations
1,448 Views
13 Pages

Evaluating [18F]-DCFPyL for Detecting Prostate Cancer Recurrence: A Cost–Consequence Comparison with Alternative PET Radiotracers in Spain

  • Tiago Matos,
  • Mrunmayee Godbole,
  • Rithvik Badinedi,
  • Madhusubramanian Muthukumar and ,
  • Marina Hodolic,
  • Nicolas Tchouen and
  • Anthony Berthon
  • + 2 authors+ 0 author

Introduction: [18F]-DCFPyL (Piflufolastat [18F]) is a prostate-specific membrane antigen (PSMA)-targeted position emission tomography (PET) radiotracer for detecting the biochemical recurrence (BCR) of prostate cancer (PCa). This study evaluates its...

  • Article
  • Open Access
33 Citations
3,960 Views
12 Pages

18F-Fluorocholine PET and Multiphase CT Integrated in Dual Modality PET/4D-CT for Preoperative Evaluation of Primary Hyperparathyroidism

  • Valentin Pretet,
  • Marianela Rotania,
  • Mehdi Helali,
  • Mihaela Ignat and ,
  • Michel Vix and
  • Alessio Imperiale
  • + 1 author+ 0 author

26 June 2020

The present retrospective study evaluates the diagnostic value of integrated 18F-Fluorocholine positron emission tomography/four-dimensional contrast-enhanced computed tomography (18F-FCH PET/4D-CT) as second-line imaging in preoperative work-up of p...

(This article belongs to the Section Nuclear Medicine & Radiology)
  • Article
  • Open Access
2 Citations
2,209 Views
10 Pages

Carotid Artery Temperature Reduction with Statin Therapy in Patients with Familial Hyperlipidemia Syndromes

  • Georgios Benetos,
  • Spyros Galanakos,
  • Iosif Koutagiar,
  • Ioannis Skoumas and ,
  • Georgios Oikonomou,
  • Maria Drakopoulou,
  • Maria Karmpalioti,
  • Vasiliki Katsi,
  • Costas Tsioufis and
  • Konstantinos Toutouzas
  • + 5 authors+ 0 author

27 October 2021

Background: Microwave radiometry (MWR) assesses non-invasive carotid artery temperatures reflecting inflammation. In the present study, we aimed to investigate the impact of hypolipidemic therapy either with simvastatin or with combination simvastati...

(This article belongs to the Section Cardiovascular Medicine)
  • Article
  • Open Access
9 Citations
3,817 Views
14 Pages

Contribution of Litter Layer to Greenhouse Gas Fluxes between Atmosphere and Soil Varies with Forest Succession

  • Jun Jiang,
  • Ying-Ping Wang,
  • Hao Zhang,
  • Mengxiao Yu and ,
  • Fengcai Liu,
  • Shiting Xia and
  • Junhua Yan
  • + 2 authors+ 0 author

31 March 2022

Surface litter layer strongly influences CO2, N2O, and CH4 fluxes (FCO2, FN2O, and FCH4) between the atmosphere and forest floor through litter decomposition (litter-internal, fL-L) or interactions between litter and mineral soil (litter-induced, fL-...

(This article belongs to the Section Forest Ecology and Management)
  • Article
  • Open Access
13 Citations
2,848 Views
19 Pages

13 August 2023

Quantification of water carbon fluxes in rice paddies and analysis of their causes are essential for agricultural water management and carbon budgets. In this regard, two tree-based machine learning models, which are extreme gradient boosting (XGBoos...

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