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158,410 Results Found

  • Article
  • Open Access
3,073 Views
12 Pages

23 August 2020

The dA::dGoxo pair appearing in nucleic ds-DNA can lead to a mutation in the genetic information. Depending on the dGoxo source, an AT→GC and GC→AC transversion might be observed. As a result, glycosylases are developed during the evolution...

  • Article
  • Open Access
8,024 Views
12 Pages

26,26,26,27,27,27-Hexadeuterated-1,25-Dihydroxyvitamin D3 (1,25D-d6) As Adjuvant of Chemotherapy in Breast Cancer Cell Lines

  • Samuel Seoane,
  • Maria A. Bermudez,
  • Juan Sendon-Lago,
  • Anxo Martinez-Ordoñez,
  • Soraya Abdul-Hadi,
  • Miguel Maestro,
  • Antonio Mouriño and
  • Roman Perez-Fernandez

27 December 2013

It has been demonstrated that 1,25-dihydroxyvitamin D3 (1,25D) and some of its analogues have antitumor activity. 1,25D labeled with deuterium (26,26,26,27,27,27-hexadeuterated 1a,25-dihydroxyvitamin D3, or 1,25D-d6) is commonly used as internal sta...

  • Article
  • Open Access
7 Citations
2,477 Views
20 Pages

9 June 2024

This paper addresses the problem of removing 3D effects as one of the most challenging problems related to 2D electrical resistivity tomography (ERT) monitoring of embankment structures. When processing 2D ERT monitoring data measured along linear pr...

  • Article
  • Open Access
1 Citations
2,440 Views
11 Pages

Vitamin D3, 25-Hydroxyvitamin D3, and 1,25-Dihydroxyvitamin D3 Uptake in Cultured Human Mature Adipocytes

  • Nazlı Uçar,
  • Richard. T. Pickering,
  • Peter M. Mueller,
  • Jude T. Deeney,
  • María Morales Suárez-Varela,
  • José Miguel Soriano and
  • Michael F. Holick

25 June 2025

Background/Objectives: Vitamin D3 is predominantly sequestered in adipose tissue, where it is slowly mobilized under conditions of deficiency in vivo. However, the kinetics of its uptake, release, and interaction with its major metabolites, 25(OH)D3...

  • Short Note
  • Open Access
4 Citations
3,809 Views
4 Pages

4-Bromobenzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole)

  • Timofey N. Chmovzh,
  • Daria A. Alekhina,
  • Timofey A. Kudryashev and
  • Oleg A. Rakitin

12 May 2022

Bromoderivatives of benzofused 1,2,5-thiadiazoles are important precursors for the synthesis of dyes, which are widely used to design effective photovoltaic materials. In this study, 4-bromobenzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole was selectiv...

  • Article
  • Open Access
4 Citations
5,473 Views
8 Pages

d-Idose, d-Iduronic Acid, and d-Idonic Acid from d-Glucose via Seven-Carbon Sugars

  • Zilei Liu,
  • Sarah F. Jenkinson,
  • Akihide Yoshihara,
  • Mark R. Wormald,
  • Ken Izumori and
  • George W. J. Fleet

18 October 2019

A practical synthesis of the very rare sugar d-idose and the stable building blocks for d-idose, d-iduronic, and d-idonic acids from ido-heptonic acid requires only isopropylidene protection, Shing silica gel-supported periodate cleavage of the C6-C7...

  • Article
  • Open Access
4 Citations
3,650 Views
15 Pages

Palladium-catalyzed direct (het)arylation reactions of strongly electron-withdrawing tricyclic benzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole) and its 4,8-dibromo derivative were studied; the conditions for the selective formation of mono- and bis-a...

  • Article
  • Open Access
2,693 Views
17 Pages

2D3D-DescNet: Jointly Learning 2D and 3D Local Feature Descriptors for Cross-Dimensional Matching

  • Shuting Chen,
  • Yanfei Su,
  • Baiqi Lai,
  • Luwei Cai,
  • Chengxi Hong,
  • Li Li,
  • Xiuliang Qiu,
  • Hong Jia and
  • Weiquan Liu

8 July 2024

The cross-dimensional matching of 2D images and 3D point clouds is an effective method by which to establish the spatial relationship between 2D and 3D space, which has potential applications in remote sensing and artificial intelligence (AI). In thi...

  • Article
  • Open Access
16 Citations
8,288 Views
15 Pages

31 March 2018

With the development of 3D printing, weapons are easily printed without any restriction from the production managers. Therefore, anti-3D weapon model detection is necessary issue in safe 3D printing to prevent the printing of 3D weapon models. In thi...

  • Article
  • Open Access
4 Citations
2,241 Views
16 Pages

9 September 2024

We discuss 1D, 2D and 3D bifurcation diagrams of two nonlinear dynamical systems: an electric arc system having both chaotic and periodic steady-state responses and a cytosolic calcium system with both periodic/chaotic and constant steady-state outpu...

  • Article
  • Open Access
24 Citations
4,257 Views
9 Pages

22 October 2021

Holographic display has the potential to be utilized in many 3D application scenarios because it provides all the depth cues that human eyes can perceive. However, the shortage of 3D content has limited the application of holographic 3D displays. To...

  • Feature Paper
  • Article
  • Open Access
22 Citations
6,107 Views
10 Pages

The Effect of Vitamin D Supplementation on its Metabolism and the Vitamin D Metabolite Ratio

  • Vito Francic,
  • Stan R. Ursem,
  • Niek F. Dirks,
  • Martin H. Keppel,
  • Verena Theiler-Schwetz,
  • Christian Trummer,
  • Marlene Pandis,
  • Valentin Borzan,
  • Martin R. Grübler and
  • Barbara Obermayer-Pietsch
  • + 5 authors

21 October 2019

25-hydroxyvitamin D (25(OH)D) is commonly measured to assess vitamin D status. Other vitamin D metabolites such as 24,25-dihydroxyvitamin D (24,25(OH)2D) provide additional insights into vitamin D status or metabolism. Earlier studies suggested that...

  • Review
  • Open Access
123 Citations
14,844 Views
19 Pages

9 August 2018

Fluid milk products are systematically, either mandatorily or voluntarily, fortified with vitamin D in some countries but their overall contribution to vitamin D intake and status worldwide is not fully understood. We searched the PubMed database to...

  • Article
  • Open Access
12 Citations
3,669 Views
12 Pages

24,25-Dihydroxy Vitamin D and Vitamin D Metabolite Ratio as Biomarkers of Vitamin D in Chronic Kidney Disease

  • Seunghye Lee,
  • Hye Jin Chung,
  • Sehyun Jung,
  • Ha Nee Jang,
  • Se-Ho Chang,
  • Hyun-Jung Kim and
  • Min-Chul Cho

22 January 2023

The appropriate management of vitamin D deficiency and hyperparathyroidism is essential to prevent metabolic bone disorder (MBD) and cardiovascular diseases in chronic kidney disease (CKD). Recently, the 24,25-dihydroxyvitamin D [24,25(OH)2D] and vit...

  • Article
  • Open Access
2,951 Views
16 Pages

Simulation of Flood-Control Reservoirs: Comparing Fully 2D and 0D–1D Models

  • Susanna Dazzi,
  • Riccardo Verbeni,
  • Paolo Mignosa and
  • Renato Vacondio

26 October 2024

Flood-control reservoirs are often used as a structural measure to mitigate fluvial floods, and numerical models are a fundamental tool for assessing their effectiveness. This work aims to analyze the suitability of fully 2D shallow-water models to s...

  • Article
  • Open Access
21 Citations
10,840 Views
17 Pages

Autostereoscopic 3D Display System for 3D Medical Images

  • Dongwoo Kang,
  • Jin-Ho Choi and
  • Hyoseok Hwang

24 April 2022

Recent advances in autostereoscopic three-dimensional (3D) display systems have led to innovations in consumer electronics and vehicle systems (e.g., head-up displays). However, medical images with stereoscopic depth provided by 3D displays have yet...

  • Article
  • Open Access
1 Citations
2,035 Views
35 Pages

Int.2D-3D-CNN: Integrated 2D and 3D Convolutional Neural Networks for Video Violence Recognition

  • Wimolsree Getsopon,
  • Sirawan Phiphitphatphaisit,
  • Emmanuel Okafor and
  • Olarik Surinta

19 August 2025

Intelligent video analysis tools have advanced significantly, with numerous cameras installed in various locations to enhance security and monitor unusual events. However, the effective detection and monitoring of violent incidents often depend on ma...

  • Article
  • Open Access
333 Views
22 Pages

6 January 2026

This study compares the numerical results obtained with an axisymmetric quasi two-dimensional (Q2D) model with those from two different types of dimensional models for smooth–turbulent transient flows generated by an instantaneous valve closure...

  • Article
  • Open Access
5 Citations
2,999 Views
12 Pages

16 December 2022

The objective of our study was to evaluate vitamin D status and its predictors in Slovenian premenopausal and postmenopausal women. A cross-sectional study was carried out between 1 March 2021 and 31 May 2021. A total of 319 healthy women from the Ce...

  • Article
  • Open Access
6 Citations
4,610 Views
16 Pages

Effects of High-Dose Vitamin D Supplementation on Placental Vitamin D Metabolism and Neonatal Vitamin D Status

  • Anna Louise Vestergaard,
  • Matilde Kanstrup Andersen,
  • Helena Hørdum Andersen,
  • Krista Agathe Bossow,
  • Pinar Bor and
  • Agnete Larsen

5 July 2024

Vitamin D (vitD) deficiency (25-hydroxy-vitamin D < 50 nmol/L) is common in pregnancy and associated with an increased risk of adverse pregnancy outcomes. High-dose vitD supplementation is suggested to improve pregnancy health, but there is limite...

  • Article
  • Open Access
2 Citations
4,845 Views
12 Pages

13 October 2017

In this paper, we investigate a resource management scheme for cellular underlaid device-to-device (D2D) communications, which are an integral part of mobile caching networks. D2D communications are allowed to share radio resources with cellular comm...

  • Article
  • Open Access
37 Citations
6,160 Views
16 Pages

Association of Dietary Vitamin D Intake, Serum 25(OH)D3, 25(OH)D2 with Cognitive Performance in the Elderly

  • RuTong Wang,
  • Weijing Wang,
  • Ping Hu,
  • Ronghui Zhang,
  • Xue Dong and
  • Dongfeng Zhang

2 September 2021

Background: As life expectancy increases, cognitive performance decline in the elderly has become one of the major global challenges. We aimed to evaluate the association of dietary vitamin D (VD), serum 25-hydroxyvitamin D3 (25(OH)D3), 25-hydroxyvit...

  • Article
  • Open Access
6 Citations
4,002 Views
23 Pages

True 3D Nanometrology: 3D-Probing with a Cantilever-Based Sensor

  • Jan Thiesler,
  • Thomas Ahbe,
  • Rainer Tutsch and
  • Gaoliang Dai

31 December 2021

State of the art three-dimensional atomic force microscopes (3D-AFM) cannot measure three spatial dimensions separately from each other. A 3D-AFM-head with true 3D-probing capabilities is presented in this paper. It detects the so-called 3D-Nanoprobe...

  • Review
  • Open Access
39 Citations
8,684 Views
17 Pages

3D and 4D Printing of Multistable Structures

  • Hoon Yeub Jeong,
  • Soo-Chan An,
  • Yeonsoo Lim,
  • Min Ji Jeong,
  • Namhun Kim and
  • Young Chul Jun

16 October 2020

Three-dimensional (3D) printing is a new paradigm in customized manufacturing and allows the fabrication of complex structures that are difficult to realize with other conventional methods. Four-dimensional (4D) printing adds active, responsive funct...

  • Review
  • Open Access
37 Citations
6,362 Views
20 Pages

Infrared Photodetection from 2D/3D van der Waals Heterostructures

  • Qianying Tang,
  • Fang Zhong,
  • Qing Li,
  • Jialu Weng,
  • Junzhe Li,
  • Hangyu Lu,
  • Haitao Wu,
  • Shuning Liu,
  • Jiacheng Wang and
  • Ting He
  • + 3 authors

24 March 2023

An infrared photodetector is a critical component that detects, identifies, and tracks complex targets in a detection system. Infrared photodetectors based on 3D bulk materials are widely applied in national defense, military, communications, and ast...

  • Article
  • Open Access
2 Citations
4,738 Views
21 Pages

13 April 2025

While 1D, 2D, and coupled 1D/2D models are widely used in flood extent mapping, a significant research gap remains in comparative analyses of 2D and coupled 1D/2D approaches. Study of the Dinsiz Stream Basin is of critical importance due to its proxi...

  • Proceeding Paper
  • Open Access
1,065 Views
10 Pages

7 February 2025

This paper presents an integrated CAD/CAM system that can be used for Computer Aided Process Planning to interact or automate 3D/4D/5D printing process towards Industry 5.0. By creating a new algorithm, macro is developed that has the capability to d...

  • Article
  • Open Access
56 Citations
6,400 Views
19 Pages

A Uniform Architecture Design for Accelerating 2D and 3D CNNs on FPGAs

  • Zhiqiang Liu,
  • Paul Chow,
  • Jinwei Xu,
  • Jingfei Jiang,
  • Yong Dou and
  • Jie Zhou

Three-dimensional convolutional neural networks (3D CNNs) have gained popularity in many complicated computer vision applications. Many customized accelerators based on FPGAs are proposed for 2D CNNs, while very few are for 3D CNNs. Three-D CNNs are...

  • Article
  • Open Access
8 Citations
3,590 Views
15 Pages

Measuring Vitamin D3 Metabolic Status, Comparison between Vitamin D Deficient and Sufficient Individuals

  • Laura de los Santos Castillo-Peinado,
  • Mónica Calderón-Santiago,
  • Aura Dulcinea Herrera-Martínez,
  • Soraya León-Idougourram,
  • María Ángeles Gálvez-Moreno,
  • Rafael Luis Sánchez-Cano,
  • Roger Bouillon,
  • Jose Manuel Quesada-Gómez and
  • Feliciano Priego-Capote

The main branch of vitamin D3 metabolism involves several hydroxylation reactions to obtain mono-, di- and trihydroxylated metabolites, including the circulating and active forms—25(OH)D3 and 1,25(OH)2D3, respectively. However, most clinical tr...

  • Article
  • Open Access
21 Citations
5,600 Views
14 Pages

8 December 2020

Despite the remarkable progress in perovskite solar cells (PSCs), their instability and rapid degradation over time still restrict their commercialization. A 2D capping layer has been proved to overcome the stability issues; however, an in-depth unde...

  • Article
  • Open Access
26 Citations
9,289 Views
13 Pages

A 3D Printing Model Watermarking Algorithm Based on 3D Slicing and Feature Points

  • Giao N. Pham,
  • Suk-Hwan Lee,
  • Oh-Heum Kwon and
  • Ki-Ryong Kwon

With the increase of three-dimensional (3D) printing applications in many areas of life, a large amount of 3D printing data is copied, shared, and used several times without any permission from the original providers. Therefore, copyright protection...

  • Brief Report
  • Open Access
23 Citations
6,107 Views
16 Pages

The Role of Polymorphisms in Vitamin D-Related Genes in Response to Vitamin D Supplementation

  • Sara Tomei,
  • Parul Singh,
  • Rebecca Mathew,
  • Valentina Mattei,
  • Mathieu Garand,
  • Mariam Alwakeel,
  • Elham Sharif and
  • Souhaila Al Khodor

27 August 2020

Background. Vitamin D deficiency represents a major healthcare problem. Vitamin D status is influenced by genetic and environmental determinants. Several observational studies have evaluated the association of single-nucleotide polymorphisms (SNPs) i...

  • Article
  • Open Access
5 Citations
9,135 Views
14 Pages

Automated Assembly Using 3D and 2D Cameras

  • Adam Leon Kleppe,
  • Asgeir Bjørkedal,
  • Kristoffer Larsen and
  • Olav Egeland

2D and 3D computer vision systems are frequently being used in automated production to detect and determine the position of objects. Accuracy is important in the production industry, and computer vision systems require structured environments to func...

  • Review
  • Open Access
36 Citations
20,031 Views
27 Pages

Dopamine D1–D5 Receptors in Brain Nuclei: Implications for Health and Disease

  • Ichiro Kawahata,
  • David I. Finkelstein and
  • Kohji Fukunaga

12 April 2024

Understanding the intricate role of dopamine D1–D5 receptors is pivotal in addressing the challenges posed by the aging global population, as well as by social stress and advancing therapeutic interventions. Central to diverse brain functions s...

  • Article
  • Open Access
19 Citations
7,563 Views
24 Pages

10 June 2011

Symmetry has been shown to be a very effective a priori constraint in solving a 3D shape recovery problem. Symmetry is useful in 3D recovery because it is a form of redundancy. There are, however, some fundamental limits to the effectiveness of symme...

  • Article
  • Open Access
7 Citations
3,131 Views
20 Pages

Factors Associated with Serum Vitamin D Metabolites and Vitamin D Metabolite Ratios in Premenopausal Women

  • María José Toribio,
  • Feliciano Priego-Capote,
  • Beatriz Pérez-Gómez,
  • Nerea Fernández de Larrea-Baz,
  • Emma Ruiz-Moreno,
  • Adela Castelló,
  • Pilar Lucas,
  • María Ángeles Sierra,
  • Marina Nieves Pino and
  • Marina Pollán
  • + 3 authors

23 October 2021

The most representative indicator of vitamin D status in clinical practice is 25(OH)D3, but new biomarkers could improve the assessment of vitamin D status and metabolism. The objective of this study is to investigate the association of serum vitamin...

  • Article
  • Open Access
7 Citations
4,704 Views
12 Pages

Energy Efficiency of D2D Multi-User Cooperation

  • Zufan Zhang,
  • Lu Wang and
  • Jie Zhang

28 March 2017

The Device-to-Device (D2D) communication system is an important part of heterogeneous networks. It has great potential to improve spectrum efficiency, throughput and energy efficiency cooperation of multiple D2D users with the advantage of direct com...

  • Feature Paper
  • Article
  • Open Access
11 Citations
2,753 Views
15 Pages

1 July 2023

Delayed or prolonged corneal wound healing and non-healing corneas put patients at risk for ocular surface infections and subsequent stromal opacification, resulting in discomfort or visual loss. It is important to enhance corneal wound healing effic...

  • Article
  • Open Access
40 Citations
7,815 Views
15 Pages

13 September 2022

Considerable progress has been made in the prediction methods of 3D structures of RNAs. In contrast, no such methods are available for DNAs. The determination of 3D structures of the latter is also increasingly needed for understanding their function...

  • Article
  • Open Access
8 Citations
4,096 Views
12 Pages

Efficient Utilization of Fruit Peels for the Bioproduction of D-Allulose and D-Mannitol

  • Jin Li,
  • Jiajun Chen,
  • Wei Xu,
  • Wenli Zhang,
  • Yeming Chen and
  • Wanmeng Mu

12 November 2022

Currently, the demand for low-calorie sweeteners has grown dramatically because consumers are more mindful of their health than they used to be. Therefore, bioproduction of low-calorie sweeteners from low-cost raw materials becomes a hot spot. In thi...

  • Article
  • Open Access
5 Citations
1,397 Views
19 Pages

1 December 2023

D2D communication is a promising technology for enhancing spectral efficiency (SE) in cellular networks, and full-duplex (FD) has the potential to double SE. Due to D2D’s short-distance communication and low transmittance power, it is natural t...

  • Article
  • Open Access
12 Citations
4,605 Views
15 Pages

Multiple Sclerosis Patients Show Lower Bioavailable 25(OH)D and 1,25(OH)2D, but No Difference in Ratio of 25(OH)D/24,25(OH)2D and FGF23 Concentrations

  • Mariska C Vlot,
  • Laura Boekel,
  • Jolijn Kragt,
  • Joep Killestein,
  • Barbara M. van Amerongen,
  • Robert de Jonge,
  • Martin den Heijer and
  • Annemieke C. Heijboer

15 November 2019

Vitamin D (VitD) insufficiency is common in multiple sclerosis (MS). VitD has possible anti-inflammatory effects on the immune system. The ratio between VitD metabolites in MS patients and the severity of the disease are suggested to be related. Howe...

  • Review
  • Open Access
8 Citations
3,785 Views
60 Pages

1D/2D Heterostructures: Synthesis and Application in Photodetectors and Sensors

  • Yuqian Liu,
  • Yihao Lin,
  • Yanbo Hu,
  • Wenzhao Wang,
  • Yiming Chen,
  • Zihui Liu,
  • Da Wan and
  • Wugang Liao

29 October 2024

Two-dimensional (2D) semiconductor components have excellent physical attributes, such as excellent mechanical ductility, high mobility, low dielectric constant, and tunable bandgap, which have attracted much attention to the fields of flexible devic...

  • Article
  • Open Access
18 Citations
6,559 Views
12 Pages

Vitamin D Vitamers Affect Vitamin D Status Differently in Young Healthy Males

  • Jette Jakobsen,
  • Elisabeth Anne Wreford Andersen,
  • Tue Christensen,
  • Rikke Andersen and
  • Susanne Bügel

23 December 2017

Dietary intake of vitamin D includes vitamin D3 (vitD3), 25-hydroxyvitamin D3 (25OH-D3), and vitamin D2 (vitD2). However, the bioactivity of the different species has not been scientifically established. The hypothesis in this study was that vitD3, 2...

  • Article
  • Open Access
5 Citations
7,283 Views
16 Pages

12 January 2023

Recent studies have shown that deep learning achieves excellent performance in reconstructing 3D scenes from multiview images or videos. However, these reconstructions do not provide the identities of objects, and object identification is necessary f...

  • Article
  • Open Access
10 Citations
10,289 Views
6 Pages

31 August 2005

6-Methylpurine-β-D-riboside (β-D-MPR) has been synthesized by coupling6-methylpurine and 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribose using conditions that producethe β-D-anomer exclusively. The in vitro antitumor effects of β-D-MPR and 6-methyl-purine-α-...

  • Short Note
  • Open Access
1,988 Views
4 Pages

Benzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole)-4-carbonitrile

  • Timofey N. Chmovzh,
  • Timofey A. Kudryashev,
  • Karim S. Gaisin and
  • Oleg A. Rakitin

3 July 2023

Electron-withdrawing heterocyclic units are found in most organic optoelectronic materials. Benzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole) is an interesting new heterocyclic system, the chemical properties of which are much less studied than other...

  • Article
  • Open Access
12 Citations
2,950 Views
16 Pages

Vitamin D, Vitamin D-Binding Proteins, and VDR Polymorphisms in Individuals with Hyperglycaemia

  • Rajiv Erasmus,
  • Setjie Maepa,
  • Ian Machingura,
  • Saarah Davids,
  • Shanel Raghubeer and
  • Tandi Matsha

30 July 2022

Vitamin D reportedly plays an important role in the pathogenesis of diabetes mellitus; however, this role is unclear and debated. This study investigated the association between 25(OH) vitamin D, vitamin D-binding proteins, and vitamin D receptor (VD...

  • Article
  • Open Access
12 Citations
4,797 Views
22 Pages

Robust 3D Hand Detection from a Single RGB-D Image in Unconstrained Environments

  • Chi Xu,
  • Jun Zhou,
  • Wendi Cai,
  • Yunkai Jiang,
  • Yongbo Li and
  • Yi Liu

7 November 2020

Three-dimensional hand detection from a single RGB-D image is an important technology which supports many useful applications. Practically, it is challenging to robustly detect human hands in unconstrained environments because the RGB-D channels can...

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