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  • Article
  • Open Access
1 Citations
1,317 Views
13 Pages

Impact of Pharmacist Interventions in a Portuguese Hospital: A Study Using the CLEO Multidimensional Tool

  • Sofia Silva,
  • Mafalda Jesus,
  • Sandra Faria,
  • Sara Machado and
  • Manuel Morgado

5 October 2025

(1) Background: Pharmacist interventions are key to optimizing medication therapy and improving patient outcomes. The CLEO multidimensional tool assesses the clinical, economic, and organizational impact of these interventions, though its use in Port...

  • Article
  • Open Access
23 Citations
7,457 Views
25 Pages

4 July 2024

Despite the rapid advances in deep learning (DL) for object detection, existing techniques still face several challenges. In particular, object detection in adverse weather conditions (AWCs) requires complex and computationally costly models to achie...

  • Article
  • Open Access
28 Citations
4,049 Views
14 Pages

3 August 2022

Cinnamomum longepaniculatum essential oil (CLEO) possesses antibacterial, anti-inflammatory, and antioxidant activities. However, CLEO shows volatilization and poor solubility, which limits its application field. In this research, inclusion complexes...

  • Article
  • Open Access
3 Citations
1,501 Views
15 Pages

19 November 2024

This research is intended to ascertain the impact of low-voltage electrostatic field (LVEF) together with chili pepper leaf essential oil (CLEO) on the storage quality of chili pepper. Four groups of samples were investigated, namely, control (CK), C...

  • Article
  • Open Access
44 Citations
13,673 Views
31 Pages

Citrus limon Essential Oil: Chemical Composition and Selected Biological Properties Focusing on the Antimicrobial (In Vitro, In Situ), Antibiofilm, Insecticidal Activity and Preservative Effect against Salmonella enterica Inoculated in Carrot

  • Miroslava Kačániová,
  • Natália Čmiková,
  • Nenad L. Vukovic,
  • Andrea Verešová,
  • Alessandro Bianchi,
  • Stefania Garzoli,
  • Rania Ben Saad,
  • Anis Ben Hsouna,
  • Zhaojun Ban and
  • Milena D. Vukic

15 February 2024

New goals for industry and science have led to increased awareness of food safety and healthier living in the modern era. Here, one of the challenges in food quality assurance is the presence of pathogenic microorganisms. As planktonic cells can form...

  • Article
  • Open Access
884 Views
9 Pages

Validation of the Charlotte Large Artery Occlusion Endovascular Therapy Outcome Score in a Modern Cohort of Thrombectomy Patients

  • Rahul R. Karamchandani,
  • Liang Wang,
  • Hongmei Yang,
  • Dale Strong,
  • Jeremy B. Rhoten,
  • Jonathan D. Clemente,
  • Gary Defilipp,
  • Elizabeth A. Adelman,
  • William R. Stetler and
  • Andrew W. Asimos

Background/Objectives: The Charlotte Large artery occlusion Endovascular therapy Outcome Score (CLEOS) predicts neurological outcomes after endovascular thrombectomy (EVT). Given recent expanded indications for EVT, we evaluated CLEOS in a modern coh...

  • Article
  • Open Access
1,330 Views
14 Pages

24 April 2025

Lignin-rich residues from lignocellulosic biorefineries remain underutilized, limiting their economic viability. This study demonstrates how modifying hydrothermal pretreatments with temperatures and additives enhances the lignin-rich residue’s...

  • Article
  • Open Access
11 Citations
4,062 Views
15 Pages

17 August 2022

The antioxidant and antibacterial properties of four essential oils (oregano essential oil (OEO), tea tree essential oil (TTEO), wild orange essential oil (WOEO), and clove leaf essential oil (CLEO)) were determined. The in-vitro experiment indicated...

  • Article
  • Open Access
7 Citations
2,624 Views
17 Pages

Biological Activities of Chamaecyparis lawsoniana (A.Murray bis) Parl. and Thuja plicata Donn ex D.Don Essential Oils: Toxicity, Genotoxicity, Antigenotoxicity, and Antimicrobial Activity

  • Vladimir J. Cvetković,
  • Zorica S. Mitić,
  • Zorica Stojanović-Radić,
  • Sanja Lj. Matić,
  • Biljana M. Nikolić,
  • Ljubinko Rakonjac,
  • Jovana Ickovski and
  • Gordana Stojanović

29 December 2023

Essential oils (EOs) derived from evergreen conifer trees are recognized as complex sources of agents with various biological activities. In this study, the biological activities of the EOs derived from Chamaecyparis lawsoniana (A.Murray bis) Parl. (...

  • Article
  • Open Access
17 Citations
4,333 Views
25 Pages

Extraction of Bioactive Compound-Rich Essential Oil from Cistus ladanifer L. by Microwave-Assisted Hydrodistillation: GC-MS Characterization, In Vitro Pharmacological Activities, and Molecular Docking

  • Naoufal El Hachlafi,
  • Fahd Kandsi,
  • Amine Elbouzidi,
  • Fatima Zahra Lafdil,
  • Ghizlane Nouioura,
  • Emad M. Abdallah,
  • Rhizlan Abdnim,
  • Mohamed Bnouham,
  • Samiah Hamad Al-Mijalli and
  • Kawtar Fikri-Benbrahim
  • + 1 author

Cistus ladanifer L. is an aromatic and resinous perennial shrub commonly used in Moroccan folk medicine against a range of illnesses including skin problems, diabetes, diarrhea, and inflammation. The current investigation aims to determine the bioact...

  • Article
  • Open Access
8 Citations
2,421 Views
18 Pages

30 December 2024

The volatility, instability, and water insolubility of Camphora longepaniculata essential oil (CLEO) limit its practical applications in the food, pharmaceutical, and cosmetics industries. CLEO nanoemulsions (CLNEs) were formulated and characterized...

  • Article
  • Open Access
2 Citations
1,822 Views
21 Pages

Influence of Glycerol and Tween on Yeast Films Functionalized with Cinnamon and Lavender Essential Oils

  • Iulia Bleoanca,
  • Mihaela Turturica,
  • Iuliana Aprodu,
  • Felicia Stan,
  • Catalin Fetecau and
  • Daniela Borda

21 January 2025

Sustainable food packaging solutions replacing the current petroleum-based ones are sparking researchers’ interest in the development of innovative applications. This study developed and characterized an edible film as a food packaging material...

  • Article
  • Open Access
26 Citations
4,924 Views
13 Pages

Antioxidant and Antimicrobial Effect of Plant Essential Oils and Sambucus nigra Extract in Salmon Burgers

  • Kristina Jonušaite,
  • Petras Rimantas Venskutonis,
  • Gines Benito Martínez-Hernández,
  • Amaury Taboada-Rodríguez,
  • Gema Nieto,
  • Antonio López-Gómez and
  • Fulgencio Marín-Iniesta

4 April 2021

The antioxidant capacity of oregano (OEO) and clove (CLEO) essential oils and black elderberry (Sambucus nigra) flower extract (SNE) were compared with butylhydroxytoluene (BHT) regarding its protection against lipid peroxidation and microbial counts...

  • Article
  • Open Access
76 Citations
12,781 Views
31 Pages

Towards Controlling the Glycoform: A Model Framework Linking Extracellular Metabolites to Antibody Glycosylation

  • Philip M. Jedrzejewski,
  • Ioscani Jimenez Del Val,
  • Antony Constantinou,
  • Anne Dell,
  • Stuart M. Haslam,
  • Karen M. Polizzi and
  • Cleo Kontoravdi

14 March 2014

Glycoproteins represent the largest group of the growing number of biologically-derived medicines. The associated glycan structures and their distribution are known to have a large impact on pharmacokinetics. A modelling framework was developed to pr...

  • Article
  • Open Access
19 Citations
6,991 Views
22 Pages

The Effects of Combined Motor Control and Isolated Extensor Strengthening versus General Exercise on Paraspinal Muscle Morphology, Composition, and Function in Patients with Chronic Low Back Pain: A Randomized Controlled Trial

  • Maryse Fortin,
  • Meaghan Rye,
  • Alexa Roussac,
  • Chanelle Montpetit,
  • Jessica Burdick,
  • Neda Naghdi,
  • Brent Rosenstein,
  • Cleo Bertrand,
  • Luciana G. Macedo and
  • Véronique Pepin
  • + 4 authors

12 September 2023

Low back pain (LBP), a globally widespread and persistent musculoskeletal disorder, benefits from exercise therapy. However, it remains unclear which type leads to greater changes in paraspinal muscle health. This study aimed to (1) compare the effec...

  • Article
  • Open Access
18 Citations
10,362 Views
24 Pages

Recent research in architectural neuroscience has found that visual exposure to biophilic design may help reduce occupant physiological stress responses. However, there are still significant gaps in our understanding of the complex ways in which biop...

  • Article
  • Open Access
4 Citations
2,796 Views
18 Pages

Effect of Irrigation on Sugarcane Morphophysiology in the Brazilian Cerrado

  • Laryssa Maria Teles Batista,
  • Walter Quadros Ribeiro Junior,
  • Maria Lucrecia Gerosa Ramos,
  • Vinicius Bof Bufon,
  • Rodrigo Zuketta Sousa,
  • Christina Cleo Vinson and
  • Sidnei Deuner

23 March 2024

Since sugarcane is semi-perennial, it has no escape from water stresses in the Brazilian Cerrado, and consequently, drought impacts plant growth and industrial quality. The objective of this study was to evaluate the morphophysiology and quality of t...

  • Article
  • Open Access
5 Citations
2,911 Views
18 Pages

7 April 2022

Background: Segmentation is, in many Pathomics projects, an initial step. Usually, in supervised settings, well-annotated and large datasets are required. Regarding the rarity of such datasets, unsupervised learning concepts appear to be a potential...

  • Article
  • Open Access
56 Citations
5,036 Views
24 Pages

Grade Prediction Modeling in Hybrid Learning Environments for Sustainable Engineering Education

  • Zoe Kanetaki,
  • Constantinos Stergiou,
  • Georgios Bekas,
  • Sébastien Jacques,
  • Christos Troussas,
  • Cleo Sgouropoulou and
  • Abdeldjalil Ouahabi

26 April 2022

Since mid-March 2020, due to the COVID-19 pandemic, higher education has been facing a very uncertain situation, despite the hasty implementation of information and communication technologies for distance and online learning. Hybrid learning, i.e., t...

  • Article
  • Open Access
13 Citations
4,145 Views
16 Pages

Personalizing Environmental Awareness through Smartphones Using AHP and PROMETHEE II

  • Akrivi Krouska,
  • Katerina Kabassi,
  • Christos Troussas and
  • Cleo Sgouropoulou

21 February 2022

Environmental awareness refers to the understanding of the importance of protecting the natural environment. Digital technologies can play an important role in raising awareness of environmental issues. In view of this compelling need, this paper pre...

  • Article
  • Open Access
3 Citations
2,129 Views
17 Pages

23 June 2025

This study explores the utilization of digital escape rooms for promoting environmental education. The goal is to investigate the effectiveness of this technology in enhancing users’ environmental knowledge and eco-friendly behaviors in their d...

  • Article
  • Open Access
1 Citations
3,228 Views
20 Pages

A Hybrid Neuro-Symbolic Pipeline for Coreference Resolution and AMR-Based Semantic Parsing

  • Christos Papakostas,
  • Christos Troussas,
  • Akrivi Krouska and
  • Cleo Sgouropoulou

24 June 2025

Large Language Models (LLMs) have transformed Natural Language Processing (NLP), yet they continue to struggle with deep semantic understanding, particularly in tasks like coreference resolution and structured semantic inference. This study presents...

  • Article
  • Open Access
8 Citations
6,911 Views
24 Pages

24 June 2025

The built environment is increasingly recognized as a critical determinant of human health, profoundly influencing neurophysiological and psychological well-being. Previous studies show that specific visual patterns can elicit cortical hyperexcitatio...

  • Article
  • Open Access
52 Citations
7,139 Views
19 Pages

Noninvasive Imaging of the Immune Checkpoint LAG-3 Using Nanobodies, from Development to Pre-Clinical Use

  • Quentin Lecocq,
  • Katty Zeven,
  • Yannick De Vlaeminck,
  • Sandrina Martens,
  • Sam Massa,
  • Cleo Goyvaerts,
  • Geert Raes,
  • Marleen Keyaerts,
  • Karine Breckpot and
  • Nick Devoogdt

29 September 2019

Immune checkpoint inhibition (ICI) is a promising cancer therapy, which has progressed rapidly from a preclinical concept to clinical implementation. Commonly considered targets in ICI are CTLA-4, PD-1/PD-L1, and LAG-3, and the list grows. As ICI is...

  • Article
  • Open Access
20 Citations
3,922 Views
16 Pages

ANLN and TLE2 in Muscle Invasive Bladder Cancer: A Functional and Clinical Evaluation Based on In Silico and In Vitro Data

  • Sheng Wu,
  • Katja Nitschke,
  • Jakob Heinkele,
  • Cleo-Aron Weis,
  • Thomas Stefan Worst,
  • Markus Eckstein,
  • Stefan Porubsky and
  • Philipp Erben

21 November 2019

Anilin actin binding protein (ANLN) and transducing-like enhancer protein 2 (TLE2) are associated with cancer patient survival and progression. The impact of their gene expression on progression-free survival (PFS) of patients with muscle invasive bl...

  • Feature Paper
  • Article
  • Open Access
10 Citations
8,943 Views
14 Pages

Techno-Economic Assessment of Cell-Free Synthesis of Monoclonal Antibodies Using CHO Cell Extracts

  • Vaishali Thaore,
  • Dimitrios Tsourapas,
  • Nilay Shah and
  • Cleo Kontoravdi

12 April 2020

Cell-free protein synthesis (CFPS) is an emerging tool for the rapid production of difficult-to-express proteins as well as for identifying protein synthesis bottlenecks. In CFPS, the biotic phase is substituted by extracts of living cells devoid of...

  • Article
  • Open Access
32 Citations
8,004 Views
13 Pages

Are Non-Perennial Rivers Considered as Valuable and Worthy of Conservation as Perennial Rivers?

  • Pablo Rodríguez-Lozano,
  • Cleo Woelfle-Erskine,
  • Michael T. Bogan and
  • Stephanie M. Carlson

17 July 2020

Non-perennial rivers, watercourses that cease to flow at some point in time and space, are widespread globally but often lack effective protections. Although it is thought that these ecosystems are undervalued by society, empirical studies exploring...

  • Article
  • Open Access
5 Citations
3,271 Views
15 Pages

Detection of Extreme Phenomena in the Stable Boundary Layer over the Amazonian Forest

  • Francisco O. Miranda,
  • Fernando M. Ramos,
  • Celso von Randow,
  • Cléo Q. Dias-Júnior,
  • Marcelo Chamecki,
  • Jose D. Fuentes,
  • Antônio O. Manzi,
  • Marceliano E. de Oliveira and
  • Cledenilson M. de Souza

6 September 2020

We apply different methods for detection of extreme phenomena (EP) in air-turbulent time series measured in the nocturnal boundary layer above the Amazon forest. The methods used were: (a) a Morlet complex wavelet transform, which is often used in an...

  • Article
  • Open Access
15 Citations
3,950 Views
12 Pages

Cerebrospinal Fluid Biomarker Profile in TDP-43-Related Genetic Frontotemporal Dementia

  • Elisabeth Kapaki,
  • Foteini Boufidou,
  • Mara Bourbouli,
  • Efstratios-Stylianos Pyrgelis,
  • Vasilios C. Constantinides,
  • Cleo Anastassopoulou and
  • George P. Paraskevas

21 October 2022

Cerebrospinal fluid (CSF) biomarkers, namely total tau, phospho-tau and amyloid beta peptides, have received much attention specifically regarding Alzheimer’s disease (AD), since they can detect the biochemical fingerprint of AD and serve as a...

  • Article
  • Open Access
11 Citations
5,051 Views
16 Pages

Virtual architecture has been increasingly relied on to evaluate the health impacts of physical architecture. In this health research, exposure to virtual architecture has been used as a proxy for exposure to physical architecture. Despite the growin...

  • Article
  • Open Access
11 Citations
2,917 Views
16 Pages

8 February 2023

Soybean is a crop in high demand, in particular as a crucial source of plant protein. As a short-day plant, soybean is sensitive to the latitude of the growing site. Consequently, varieties that are well adapted to higher latitudes are required to ex...

  • Editorial
  • Open Access
7 Citations
3,403 Views
6 Pages

The Role of Oral Antivirals for COVID-19 Treatment in Shaping the Pandemic Landscape

  • Cleo Anastassopoulou,
  • Sophia Hatziantoniou,
  • Fotini Boufidou,
  • George P. Patrinos and
  • Athanasios Tsakris

11 March 2022

Several vaccines against coronavirus disease 2019 (COVID-19) were developed and made available in a record time, just over a year after the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [...]

  • Feature Paper
  • Article
  • Open Access
4 Citations
2,664 Views
9 Pages

The Burden of Urinary Tract Infections on Quality of Life and Healthcare in Patients with Interstitial Cystitis

  • Cléo Baars,
  • Charlotte van Ginkel,
  • John Heesakkers,
  • Mathilde Scholtes,
  • Frank Martens and
  • Dick Janssen

18 October 2023

Background: Interstitial cystitis/bladder pain syndrome (IC/BPS) patients are more susceptible to urinary tract infections (UTIs), likely worsening pre-existing symptoms. However, this receives limited attention in guidelines. This study aimed to exp...

  • Article
  • Open Access
1 Citations
1,646 Views
17 Pages

Predominance of Recombinant Norovirus Strains in Greece, 2016–2018

  • Nikolaos Siafakas,
  • Cleo Anastassopoulou,
  • Maria Lafazani,
  • Genovefa Chronopoulou,
  • Emmanouil Rizos,
  • Spyridon Pournaras and
  • Athanasios Tsakris

GII.4 noroviruses have caused the overwhelming majority of norovirus-related gastroenteritis cases during the past two decades. However, a trend towards the emergence of new genotypes and novel GII.4 variants provided the impetus to explore further t...

  • Communication
  • Open Access
1,883 Views
8 Pages

Bode Phase Angle Signaling of a TB Disease Biomarker

  • Unathi Sidwaba,
  • Kaylin Cleo Januarie,
  • Sixolile Mini,
  • Kefilwe Vanessa Mokwebo,
  • Emmanuel Iwuoha and
  • Usisipho Feleni

15 December 2023

Tuberculosis (TB) is a worldwide burden whose total control and eradication remains a challenge due to factors including false positive/negative diagnoses associated with the poor sensitivity of the current diagnostics in immune-compromised and post-...

  • Article
  • Open Access
5 Citations
2,646 Views
14 Pages

Artificial Intelligence-Assisted Detection of Osteoporotic Vertebral Fractures on Lateral Chest Radiographs in Post-Menopausal Women

  • Jenna Silberstein,
  • Cleo Wee,
  • Ashu Gupta,
  • Hannah Seymour,
  • Switinder Singh Ghotra,
  • Cláudia Sá dos Reis,
  • Guicheng Zhang and
  • Zhonghua Sun

16 December 2023

Osteoporotic vertebral fractures (OVFs) are often not reported by radiologists on routine chest radiographs. This study aims to investigate the clinical value of a newly developed artificial intelligence (AI) tool, Ofeye 1.0, for automated detection...

  • Article
  • Open Access
7 Citations
2,511 Views
13 Pages

Long-Term Measurements of the Atmospheric Boundary Layer Height in Central Amazonia Using Remote Sensing Instruments

  • Carla Maria Alves Souza,
  • Cléo Quaresma Dias-Júnior,
  • Flávio Augusto F. D’Oliveira,
  • Hardiney Santos Martins,
  • Rayonil Gomes Carneiro,
  • Bruno Takeshi Tanaka Portela and
  • Gilberto Fisch

25 June 2023

The height (zi) of the Atmospheric Boundary Layer (ABL) is a fundamental parameter for several areas of knowledge, especially for weather and climate forecasting, pollutant dispersion and air quality. In this work, we used data from a remote sensing...

  • Review
  • Open Access
61 Citations
10,386 Views
19 Pages

SARS-CoV-2 Reinfections and Long COVID in the Post-Omicron Phase of the Pandemic

  • Fotini Boufidou,
  • Snežana Medić,
  • Vicky Lampropoulou,
  • Nikolaos Siafakas,
  • Athanasios Tsakris and
  • Cleo Anastassopoulou

19 August 2023

We are reviewing the current state of knowledge on the virological and immunological correlates of long COVID, focusing on recent evidence for the possible association between the increasing number of SARS-CoV-2 reinfections and the parallel pandemic...

  • Feature Paper
  • Review
  • Open Access
338 Citations
79,198 Views
21 Pages

Virtual Reality in Education: A Review of Learning Theories, Approaches and Methodologies for the Last Decade

  • Andreas Marougkas,
  • Christos Troussas,
  • Akrivi Krouska and
  • Cleo Sgouropoulou

In the field of education, virtual reality (VR) offers learners an immersive and interactive learning experience, allowing them to comprehend challenging concepts and ideas more efficiently and effectively. VR technology has enabled educators to deve...

  • Article
  • Open Access
1 Citations
2,686 Views
21 Pages

Unraveling a Histopathological Needle-in-Haystack Problem: Exploring the Challenges of Detecting Tumor Budding in Colorectal Carcinoma Histology

  • Daniel Rusche,
  • Nils Englert,
  • Marlen Runz,
  • Svetlana Hetjens,
  • Cord Langner,
  • Timo Gaiser and
  • Cleo-Aron Weis

22 January 2024

Background: In this study focusing on colorectal carcinoma (CRC), we address the imperative task of predicting post-surgery treatment needs by identifying crucial tumor features within whole slide images of solid tumors, analogous to locating a needl...

  • Article
  • Open Access
3 Citations
2,979 Views
17 Pages

Strategic Planning of a Joint SARS-CoV-2 and Influenza Vaccination Campaign in the UK

  • Dauda Ibrahim,
  • Zoltán Kis,
  • Maria M. Papathanasiou,
  • Cleo Kontoravdi,
  • Benoît Chachuat and
  • Nilay Shah

3 February 2024

The simultaneous administration of SARS-CoV-2 and influenza vaccines is being carried out for the first time in the UK and around the globe in order to mitigate the health, economic, and societal impacts of these respiratory tract diseases. However,...

  • Article
  • Open Access
6 Citations
7,160 Views
24 Pages

4 February 2024

The need for effective cognitive training methodologies has increased, particularly for individuals dealing with Attention Deficit Hyperactivity Disorder (ADHD). In response to this demand, Virtual Reality (VR) technology emerges as a promising tool...

  • Article
  • Open Access
10 Citations
3,983 Views
16 Pages

7 February 2024

Background: There is a significant need to monitor human cognitive performance in complex environments, with one example being pilot performance. However, existing assessments largely focus on subjective experiences (e.g., questionnaires) and the eva...

  • Review
  • Open Access
3 Citations
5,748 Views
13 Pages

Investigating ABO Blood Groups and Secretor Status in Relation to SARS-CoV-2 Infection and COVID-19 Severity

  • Stefanos Ferous,
  • Nikolaos Siafakas,
  • Fotini Boufidou,
  • George P. Patrinos,
  • Athanasios Tsakris and
  • Cleo Anastassopoulou

26 March 2024

The ABO blood groups, Lewis antigens, and secretor systems are important components of transfusion medicine. These interconnected systems have been also shown to be associated with differing susceptibility to bacterial and viral infections, likely as...

  • Article
  • Open Access
1 Citations
1,789 Views
13 Pages

Oropharyngeal Microbiome Analysis in Patients with Varying SARS-CoV-2 Infection Severity: A Prospective Cohort Study

  • Panagiotis Siasios,
  • Evangelia Giosi,
  • Konstantinos Ouranos,
  • Maria Christoforidi,
  • Ifigenia Dimopoulou,
  • Enada Leshi,
  • Maria Exindari,
  • Cleo Anastassopoulou and
  • Georgia Gioula

29 March 2024

Patients with COVID-19 infection have distinct oropharyngeal microbiota composition and diversity metrics according to disease severity. However, these findings are not consistent across the literature. We conducted a multicenter, prospective study i...

  • Review
  • Open Access
22 Citations
6,445 Views
20 Pages

Carbapenem-resistant Gram-negative bacterial infections are a major public health threat due to the limited therapeutic options available. The introduction of the new β-lactam/β-lactamase inhibitors (BL/BLIs) has, however, altered the treatment optio...

  • Article
  • Open Access
44 Citations
4,284 Views
21 Pages

Acquiring, Analyzing and Interpreting Knowledge Data for Sustainable Engineering Education: An Experimental Study Using YouTube

  • Zoe Kanetaki,
  • Constantinos Stergiou,
  • Georgios Bekas,
  • Sébastien Jacques,
  • Christos Troussas,
  • Cleo Sgouropoulou and
  • Abdeldjalil Ouahabi

With the immersion of a plethora of technological tools in the early post-COVID-19 era in university education, instructors around the world have been at the forefront of implementing hybrid learning spaces for knowledge delivery. The purpose of this...

  • Review
  • Open Access
16 Citations
5,038 Views
18 Pages

New Insights into the Molecular Interplay between Human Herpesviruses and Alzheimer’s Disease—A Narrative Review

  • Evita Athanasiou,
  • Antonios N. Gargalionis,
  • Cleo Anastassopoulou,
  • Athanassios Tsakris and
  • Fotini Boufidou

Human herpesviruses (HHVs) have been implicated as possible risk factors in Alzheimer’s disease (AD) pathogenesis. Persistent lifelong HHVs infections may directly or indirectly contribute to the generation of AD hallmarks: amyloid beta (A&beta...

  • Article
  • Open Access
14 Citations
3,755 Views
17 Pages

GMMA as an Alternative Carrier for a Glycoconjugate Vaccine against Group A Streptococcus

  • Elena Palmieri,
  • Zoltán Kis,
  • James Ozanne,
  • Roberta Di Benedetto,
  • Beatrice Ricchetti,
  • Luisa Massai,
  • Martina Carducci,
  • Davide Oldrini,
  • Gianmarco Gasperini and
  • Francesca Micoli
  • + 5 authors

28 June 2022

Group A Streptococcus (GAS) causes about 500,000 annual deaths globally, and no vaccines are currently available. The Group A Carbohydrate (GAC), conserved across all GAS serotypes, conjugated to an appropriate carrier protein, represents a promising...

  • Case Report
  • Open Access
13 Citations
7,414 Views
17 Pages

Addressing Different Needs: The Challenges Faced by India as the Largest Vaccine Manufacturer While Conducting the World’s Biggest COVID-19 Vaccination Campaign

  • Cinja Nadana Koller,
  • Cléo Josephine Schwerzmann,
  • Alexia Suzanne Aimée Lang,
  • Eleni Alexiou and
  • Jaya Krishnakumar

17 September 2021

The COVID-19 pandemic has highlighted some of the challenges that countries face when balancing domestic and global necessities, for example with regard to vaccine needs, production and distribution. As India hosts one of the world’s largest vaccine...

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