A complex composed of Pba3-Pba4 and subunits α5, α6, and α7 is identified as an early intermediate in proteasome core particle assembly in wild-type Saccharomyces cerevisiae cells. The same complex can be reconstituted from recombin...
Although water splitting is a promising method to produce clean hydrogen energy, it requires efficient and low-cost catalysts for the oxygen evolution reaction (OER). This study focused on plasma treatment’s significance of surface oxygen vacan...
Excessive fat accumulation is a common phenomenon in cultured fish, which can cause metabolic disease such as fatty liver. However, the relative regulatory approach remains to be explored. Based on this, two feeding trials were conducted. Firstly, fi...
Phenylbutyrate (PBA) is a derivative of Butyric Acid (BA), which has the characteristics of being a histone deacetylase (HDAC) inhibitor and acting as a chemical chaperone. It has the potential to counteract a variety of different diseases, from neur...
A novel glucose sensor was reported that consisted of two-dimensional (2D) Au nanosphere arrays and glucose-responsive hydrogel film. This sensor exhibited an intense diffraction signal and an obvious diffraction color on a quartz slide due to the st...
This study investigated the impact of consumer values and attitudes to consuming plant-based alternatives (PBAs), using the value–attitude–behavior framework. The research model and hypotheses were tested using a two-step approach to stru...
Japanese encephalitis virus (JEV) infection causes host endoplasmic reticulum stress (ERS) reaction, and then induces cell apoptosis through the UPR pathway, invading the central nervous system and causing an inflammation storm. The endoplasmic retic...
The aims of this study were to characterize the exposure of pregnant women living in Portugal to 3-phenoxybenzoic acid (3-PBA) and to evaluate the association of this exposure with maternal outcomes and newborn anthropometric measures. We also aimed...
Metabolites resulting from the bacterial fermentation of dietary fibers, such as short-chain fatty acids, especially butyrate, play important roles in maintaining gut health and regulating various biological effects in the skin. However, butyrate is...
Polybenzoxazine (PBa) composites based on phosphorous-containing bio-based furfurylamine type benzoxazines (D-fu) and bisphenol-A type benzoxazines (Ba) were developed for flame retardation. The structure of D-fu was analyzed by Fourier transform inf...
Background/Objectives: This study evaluated associations between urinary 3-phenoxybenzoic acid (3-PBA), a metabolite of pyrethroids, and cardiometabolic indicators in a nationally representative sample of Korean adults using data from the 2nd Korean...
To cope with increasingly complex models of engineering design problems and to obtain more accurate design solutions, this paper proposed an improved population-based, bio-inspired optimization algorithm, called the pity beetle algorithm based on phe...
The use of pyrethroids is very broad and shows increasing trends. Human biomonitoring studies represent the best approach for realistic risk estimations, but their interpretation requires a tiered approach. A previous HBM4EU study indicated levels in...
Spastic paraplegia 80 (SPG80), caused by mutations in ubiquitin-associated protein 1 (UBAP1), is a pure form of juvenile-onset hereditary spastic paraplegia (HSP) and leads to progressive motor dysfunction. Despite recent advances in the molecular an...
The importance of advanced energy-conversion devices such as water electrolysis has manifested dramatically over the past few decades because it is the current mainstay for the generation of green energy. Anodic oxygen evolution reaction (OER) in wat...
Artificial insemination (AI) with liquid-stored semen is the most prevalent and efficient assisted reproduction technique in the modern pork industry. Pyruvate dehydrogenase complex component X (PDHX) was demonstrated to be associated with sperm meta...
In this paper, drop reliability of various PBA (printed board assembly) mounting structures is investigated and compared. Then, we built SAC305 (Sn3.0Ag0.5Cu) interconnects for BGA (ball grid array) package failure model to evaluate the drop impact r...
In the current study, the Prussian blue analog decorated with zinc oxide (PBA@ZnO) was produced using a simple chemical co-precipitation method. The nanohybrid was examined using XRD, EDX, SEM, and TEM techniques, where it exhibited a polycrystalline...
Many automatic landslide detection algorithms are based on supervised classification of various remote sensing (RS) data, particularly satellite images and digital elevation models (DEMs) delivered by Light Detection and Ranging (LiDAR). Machine lear...
We developed a new probe, Gd-DO3A-Am-PBA, for imaging tumors. Our results showed active targeting of Gd-DO3A-Am-PBA to sialic acid (SA) moieties, with increased cellular labeling in vitro and enhanced tumor accumulation and retention in vivo, compare...
Australian sweet lupin, the largest legume crop grown in Western Australia, is receiving global attention from the producers of new foods. To understand the effect of protein on cheese yield, lupin milk proteins were separated from the first, second,...
Insulin injection relies on strict blood glucose monitoring. However, existing techniques and algorithms for blood glucose monitoring cannot be completed in a timely way. In this study, we have developed a new intelligent glucose-sensitive insulin de...
Bestrophin 1 (Best1) is a chloride channel that localises to the plasma membrane of retinal pigment epithelium (RPE) cells. Mutations in the BEST1 gene are associated with a group of untreatable inherited retinal dystrophies (IRDs) called bestrophino...
(1) Background: Sleep patterns are frequently disrupted in neurodegenerative disorders such as Huntington disease (HD); however, they are still poorly understood, especially their association with clinic features. Our study aimed to explore potential...
The pixel-based adaptive segmenter (PBAS) is a classic background modeling algorithm for change detection. However, it is difficult for the PBAS method to detect foreground targets in dynamic background regions. To solve this problem, based on PBAS,...
Prussian blue analogs (PBAs) are appealing cathode materials for sodium-ion batteries because of their low material cost, facile synthesis methods, rigid open framework, and high theoretical capacity. However, the poor electrical conductivity, unavoi...
It is significant for people with diabetes to know their body’s real-time glucose level, which can guide the diagnosis and treatment. Therefore, it is necessary to research continuous glucose monitoring (CGM) as it gives us real-time informatio...
The diverse application vertices of internet-of-things (IoT) including internet of vehicles (IoV), industrial IoT (IIoT) and internet of drones things (IoDT) involve intelligent communication between the massive number of objects around us. This digi...
This paper reports on the physico-chemical removal of NH4+ from the supernatant line in municipal wastewater treatment plants (WWTPs), using zinc-hexa-cyano-ferrate (ZnHCF) beads. The work is divided into three parts: First, the characteristics of th...
Lupin seeds are rich in proteins and other essential ingredients that can help to improve human health. The protein contents in both whole and split seeds of two lupin cultivars (Mandleup and PBA Jurien) were used to produce the lupin milk using the...
Fine particulate matter (PM2.5) is a significant cause of respiratory diseases and associated cellular damage. The mechanisms behind this damage have not been fully explained. This study investigated two types of cellular damage (inflammation and pyr...
Organic cation transporters (OCTs) are membrane proteins that take up monoamines, cationic drugs and xenobiotics. We previously reported novel missense mutations of organic cation transporter 3 (OCT3, SLC22A3), some with drastically impacted transpor...
Outdoor scene understanding based on the results of point cloud classification plays an important role in mobile robots and autonomous vehicles equipped with a light detection and ranging (LiDAR) system. In this paper, a novel model named Panoramic B...
With the rapid expansion of underground rail transit construction in China, the high carbon emissions associated with subway tunnels and stations have become an increasing concern. This study systematically examines the carbon emissions of prefabrica...
In recent years, 4-phenylbutyric acid (4-PBA), an FDA-approved drug, has increasingly been used as a nonspecific chemical chaperone in vitro and in vitro, but its pharmacodynamics is still not clear. In this context, we developed and validated a Liqu...
The unfolded protein response (UPR) is an adaptive response to intrinsic and external stressors, and it is mainly activated by the accumulation of misfolded proteins at the endoplasmic reticulum (ER) lumen producing ER stress. The UPR signaling netwo...
Airway inflammation and pro-inflammatory cytokines such as tumor necrosis factor alpha (TNFα) underlie the pathophysiology of respiratory diseases, including asthma. Previously, we showed that TNFα activates the inositol-requiring enzyme...
Oxidative stress is a common phenomenon in aquaculture, which can be induced by nutritional or environmental factors. Generally, oxidative stress causes poor growth performance, metabolic dysregulation, and even the death of aquatic animals. To ident...
A novel physiologically based algorithm (PBA) for the computation of fractional flow reserve (FFR) in coronary artery trees (CATs) using computational fluid dynamics (CFD) is proposed and developed. The PBA was based on an extension of Murray’s...
Bladder cancer (BC) is the second most frequent cancer of the genitourinary system. The most successful therapy since the 1970s has consisted of intravesical instillations of Bacillus Calmette–Guérin (BCG) in which the tumor microenviron...
Deep learning-based object detection methods address the problem of how to trade off the object detection accuracy and detection speed of the model. This paper proposes the PBA-YOLOv7 network algorithm, which is based on the YOLOv7 network, and first...
Physiological and molecular marker-based changes were studied in the tissues of two-year-old Pyrus pyraster (L.) Burgsd. seedlings under salt treatment. For 60 days, 5 mL of 100 mM NaCl solution was applied to each plant per day to a cumulative volum...
Sustained endoplasmic reticular stress (ERS) is implicated in aggressive metastasis of cancer cells and increased tumor cell proliferation. Cancer cells activate the unfolded protein response (UPR), which aids in cellular survival and adaptation to h...
Cerebral palsy (CP) is defined as permanent disorders of movement and posture. Prematurity and hypoxia–ischemia (HI) are risk factors of CP, and boys display a greater vulnerability to develop CP. Magnesium sulfate (MgSO4) is administered to mo...
In recent years, transition metal-based catalytic materials have garnered considerable attention, particularly those exhibiting high catalytic efficiency toward both the oxygen evolution reaction (OER) and hydrogen evolution reaction (HER). In this w...
Element doping and nanoparticle decoration of graphene is an effective strategy to fabricate biosensor electrodes for specific biomedical signal detections. In this study, a novel nonenzymatic glucose sensor electrode was developed with copper oxide...
Antimicrobial peptides from amphibian skin secretion display remarkable broad-spectrum antimicrobial activity and are thus promising for the discovery of new antibiotics. In this study, we report a novel peptide belonging to the phylloseptin family o...
The balance of strengthening and toughening of poly (lactic acid) (PLA) has been an intractable challenge of PLA nanocomposite development for many years. In this paper, core–shell nanoparticles consisting of a silica rigid core and poly (butyl...
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the degeneration of motor neurons. Mutations in the superoxide dismutase (SOD1) gene, causing protein misfolding and aggregation, were suggested as the pathogen...
An elevated level of endoplasmic reticulum (ER) stress is considered an aggravating factor for inflammatory bowel disease (IBD). To develop an ER-stress attenuator that is effective against colitis, 4-phenylbutyric acid (4-PBA), a chemical chaperone...
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