The core of the digital transition is the representation of all kinds of real-world entities and processes and an increasing number of cognitive processes by digital information and algorithms on computers. These allow for seemingly unlimited storage...
This paper presents the main messages of a South American expert roundtable (ERT) on the unintended side effects (unseens) of digital transformation. The input of the ERT comprised 39 propositions from 20 experts representing 11 different perspective...
We present the main messages of a European Expert Round Table (ERT) on the unintended side effects (unseens) of the digital transition. Seventeen experts provided 42 propositions from ten different perspectives as input for the ERT. A full-day ERT de...
This article argues that the sociotechnical context in which near-surface geothermal energy is embedded draws out its characteristic of being temporarily depletable. Thereby, the minimization of unavoidable side effects, such as cold plumes, which re...
International headlines often make mention of side effects of international cooperation, ranging from aid-fuelled corruption to the negative side effects of volunteer tourism. The OECD Development Assistance Committee, an international forum of many...
Everything began with the discovery that pesticides have long had unintended side effects on non-target species, which is illustrated by Ponepal et al [...]
The European Union has set an ambitious goal to tackle climate change, and energy efficiency in the residential sector is among the measures required to close the gap between targeted and actual greenhouse gas emissions. While different policy tools...
Side-channel analysis (SCA) is a class of attacks on the physical implementation of a cipher, which enables the extraction of confidential key information by exploiting unintended leaks generated by a device. In recent years, researchers have observe...
22 February 2022
School closure has been a common response to COVID-19. Yet, its implementation has hardly ever been based on rigorous analysis of its costs and benefits. We aim to first illustrate the unintended consequences and side effects of school closure, and t...
This study presents an approach to protect wheat gluten (WG) plastic materials against water/moisture by adhering it with a polyethylene terephthalate (PET) film using a diamine (Jeffamine®) as a coupling agent and a compression molding operation...
Driving on the unfamiliar side of the road contributes to tourist road accidents and may deter self-driving tourists from travelling to certain countries. Experienced drivers usually drive on “autopilot” but under unfamiliar circumstances...
Particle engineering of nanosized drug delivery systems (DDS) can be used as a strategic tool to influence their pharmacokinetics after intravenous (i.v.) application by the targeted adaptation of their particle properties according to the needs at t...
Classical genetic engineering and new genome editing techniques, especially the CRISPR/Cas technology, increase the possibilities for modifying the genetic material in organisms. These technologies have the potential to provide novel agricultural tra...
The article aims to provide an overview of China’s agricultural development and its sustainability by focusing on the agriculture–environmental nexus. We first review literature regarding trends in agricultural development and driving for...
Starting in June 2014, the European Central Bank (ECB) stepped up its monetary accommodation in order to counter a too prolonged period of low inflation in the euro area. This article offers a narrative of the monetary policy measures taken up to Dec...
The goal of an antiviral agent research is to find an antiviral drug that reduces viral growth without harming healthy cells. Transformations of the virus, new viral strain developments, the resistance of viral pathogens, and side effects are the cur...
While hormonal contraceptives are efficacious and available in several forms for women, perception of safety and concern over side effects are a deterrent for many. Existing non-hormonal contraceptives include permanent sterilization, copper intraute...
Polyimide (PI) has been widely used as a flexible substrate in the OLED display industry to achieve folding and other functions. However, it has unintended side effects, such as friction-greening, a green screen phenomenon caused by friction after pr...
10 December 2024
Background: This paper reviews cost containment policies to control pharmaceutical expenditure either by regulating the pharmaceutical industry or targeting the demand side. Methods: The method used was the narrative literature review of studies whic...
Botulinum Toxin injections into salivary glands (SG) up to a total dose of 100 units IncobotulinumtoxinA (IncoA) represent the treatment of choice for sialorrhea. However, BTX might also protect SG against sialotoxic radioligand cancer therapies. The...
Nature-based Solutions (NbS) have emerged as an influential framework in climate and water governance, promoted as cost-effective, resilient, and ecologically sound responses to environmental degradation. This interdisciplinary review critically exam...
During the clinical use of photobiomodulation (PBM) to manage radiotherapy-induced side effects, tumor tissue may be exposed to low-intensity laser light. Therefore, it is necessary to evaluate potential unintended PBM stimulation of tumor cells when...
Orthodontic root resorption (ORR) is an unintended side effect of orthodontic treatment, and severe ORR can affect treatment outcome. Receptor activator of nuclear factor kappa-B ligand (RANKL) has been detected in the resorbed cementum and periodont...
Seed is an essential start of any crop production. Seed, as both botanical seed and vegetive planting materials, is thus a very important component of agricultural livelihoods in food, ornamental, and industrial value chains, of local and global food...
Renal cell carcinoma (RCC) is the most common type of kidney cancer, accounting for a significant proportion of all cancer cases in Korea. This case report presents a unique instance of spontaneous dramatic tumor regression in a 42-year-old Korean ma...
The objective of this study was to map the distribution pattern of gentrification, showing the adverse effect of urban parks. The study adopted the perspective that urban parks, which have thus far been featured in urban planning without much critici...
Microbes in the 21st century are understood as symbionts ‘completing’ the human ‘superorganism’ (Homo sapiens plus microbial partners-in-health). This paper addresses a significant paradox: despite the vast majority of our genes being microbial, the...
Cancer therapy-related cardiac dysfunction (CTRCD) has emerged as a significant concern with the rise of effective cancer treatments like anthracyclines and targeted therapies such as trastuzumab. While these therapies have improved cancer survival r...
The present article gives an overview on central challenges humans face at the dawn of complex digital societies and the Internet of Things (IoT), i.e., a world completely connected to the Internet. Among the many challenges to be handled in digital...
Long-Acting Reversible Contraception (LARCs) has the potential to decrease unintended pregnancies but only if women can easily access a requested method. Retrospective electronic chart review identified women desiring LARC placement over a one-year p...
The costs of unintended side effects of agriculture such as water pollution cannot be directly observed in markets. However, the values society places on healthy agricultural environments are increasingly reflected in payments to farmers for measures...
Careful analysis of any new nanomedicine device or disposal should be undertaken to comprehensively characterize the new product before application, so that any unintended side effect is minimized. Because of the increasing number of nanotechnology-b...
The short- and long-term side effects of chemotherapy limit the maximum therapeutic dose and impair quality of life of survivors. Injury to normal tissues, especially chemotherapy-induced cardiomyopathy, is an unintended outcome that presents devasta...
Much research has been conducted in an attempt to decrease skeletal injuries in athletic horses. The objective of this literature review is to compile the findings of over three decades of research in this area, make practical recommendations, and de...
With the ever-increasing developing rate of gene and cellular therapy applications and growing accessibility due to products receiving regulatory approval, the need for effective and reliable safety mechanisms to prevent or eliminate potentially fata...
Malignant growth is expected to surpass other significant causes of death as one of the top reasons for dismalness and mortality worldwide. According to a World Health Organization (WHO) study, this illness causes approximately between 9 and 10 milli...
5 November 2020
The struggles of China’s gay sex workers—men who sell sex to other men—illustrate how the multi-layered stigma that they experience acts as a form of necropolitical power and an instrument of the state’s discrimination against...
Before selecting a proper hydraulic turbine for power generation, conflicting factors frequently emerge from the wide range of available technology alternatives. The preliminary selection of hydraulic turbines (PSHT) has been usually carried out by o...
(1) Background: Side-channel attacks (SCAs) exploit unintended information leakage to compromise cryptographic security. In cyber-physical systems (CPSs), embedded systems are inherently constrained by limited resources, restricting the implementatio...
Bone morphogenetic protein-2 (BMP-2) is widely used to enhance bone regeneration. However, because of its short half-life and rapid disappearance, large amounts of BMP-2 are needed, leading to unintended side effects. In this study, BMP-2-encapsulate...
The extent to which the digitalisation of agriculture will make a significant contribution to solving urgent sustainability challenges will depend on the design of political, legal and economic frameworks. In this context, social discourses play a ce...
Rising levels of variable renewable energy (VRE) in Australia’s National Electricity Market have been driven by a 20% renewable energy target by 2020. This certificated renewable portfolio standard has successfully driven new investment, alloca...
Digital transformation affects socioeconomic systems, bringing inevitable changes to business processes, particularly those related to resource demands, networking processes, and communication mechanisms within entrepreneurial activities. Furthermore...
(1) Purpose: In 2020, wearing of face masks was mandated in the United States in an effort to lessen transmission of the novel 2019 coronavirus disease (COVID-19) pandemic; however, long-term mask wearing may present with unintended side-effects in b...
Nanotechnology in the field of drug delivery comes with great benefits due to the unique physicochemical properties of newly developed nanocarriers. However, they may come as well with severe toxicological side effects because of unwanted accumulatio...
The aim of this study was to compare the forces and moments exerted by thermoformed aligners (TFMs) and direct printed aligners (DPAs) on the maxillary left central incisor (21) and adjacent teeth (11, 22) during lingual bodily movement of tooth 21....
It is a common practice to use a buffer zone to damp out spurious wave growth due to computational error along the lateral boundary of limited-area weather and climate models. Although it is an effective technique to maintain model stability, an unin...
Chronic wounds pose a significant healthcare challenge, impacting millions of patients worldwide and burdening healthcare systems substantially. These wounds often occur as comorbidities and are prone to infections. Such infections hinder the healing...
The journey of chemotherapeutic drugs from the site of administration to the site of action is confronted by several factors including low bioavailability, uneven distribution in major organs, limited accessibility of drug molecules to the distant tu...
Background: Emergency contraception (EC), also known as postcoital contraception, is a method used to prevent an unintended pregnancy following unprotected or inadequately protected sexual intercourse. The available options include emergency contrace...