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1,113 Results Found

  • Article
  • Open Access
4 Citations
2,754 Views
18 Pages

Transcriptome Comparison between Two Strains of Ustilago esculenta during the Mating

  • Shuqing Wang,
  • Lidan Gao,
  • Yumei Yin,
  • Yafen Zhang,
  • Jintian Tang,
  • Haifeng Cui,
  • Shiyu Li,
  • Zhongjin Zhang,
  • Xiaoping Yu and
  • Wenqiang Xia
  • + 1 author

23 December 2022

Ustilago esculenta is a smut fungus that obligately infects Zizania latifolia and stimulates tissue swelling to form galls. Unlike T-type, MT-type U. esculenta can only proliferate within plant tissues and infect the offspring of their host. Producti...

  • Article
  • Open Access
2 Citations
3,687 Views
12 Pages

Halobacterium salinarum NRC-1 is an extremophile that grows optimally at 4.3 M NaCl concentration. In spite of being an established model microorganism for the archaea domain, direct comparisons between its proteome and transcriptome during osmotic s...

  • Article
  • Open Access
2 Citations
2,582 Views
14 Pages

9 February 2022

The southern rice black-streaked dwarf virus (SRBSDV) is transmitted horizontally by Sogatella furcifera in a persistent, propagative manner. Exposure of S. furcifera females to SRBSDV-infected rice plants may trigger transcriptomic changes in the in...

  • Article
  • Open Access
10 Citations
4,276 Views
14 Pages

Comparison of Myosepta Development and Transcriptome Profiling between Blunt Snout Bream with and Tilapia without Intermuscular Bones

  • Jia-Jia Zhou,
  • Yong-Jie Chang,
  • Yu-Long Chen,
  • Xu-Dong Wang,
  • Qing Liao,
  • Rui-Hui Shi and
  • Ze-Xia Gao

10 December 2021

Intermuscular bones (IBs) are small spicule-like bones located in the myosepta of basal teleosts, which negatively affect the edibleness and economic value of fish. Blunt snout bream (Megalobrama amblycephala, with epineural and epipleural IBs) and t...

  • Article
  • Open Access
42 Citations
13,581 Views
34 Pages

Information Theory in Computational Biology: Where We Stand Today

  • Pritam Chanda,
  • Eduardo Costa,
  • Jie Hu,
  • Shravan Sukumar,
  • John Van Hemert and
  • Rasna Walia

6 June 2020

“A Mathematical Theory of Communication” was published in 1948 by Claude Shannon to address the problems in the field of data compression and communication over (noisy) communication channels. Since then, the concepts and ideas developed...

  • Article
  • Open Access
4 Citations
3,200 Views
18 Pages

Beta-cypermethrin is one of the most widely used pyrethroid insecticides. However, its continuous and extensive use developed pests’ resistance to beta-cypermethrin. To identify candidate genes for potential resistance phenotypes and facilitate...

  • Article
  • Open Access
2 Citations
3,676 Views
14 Pages

8 December 2023

Background: Traumatic spinal cord injury (SCI) is a disabling condition that affects millions of people around the world. Currently, no clinical treatment can restore spinal cord function. Comparison of molecular responses in regenerating to non-rege...

  • Article
  • Open Access
9 Citations
4,345 Views
18 Pages

7 May 2022

The deep-sea hydrothermal vent ecosystem is one of the extreme chemoautotrophic environments. Shinkaicaris leurokolos Kikuchi and Hashimoto, 2000, and Alvinocaris longirostris Kikuchi and Ohta, 1995, are typically co-distributed and closely related a...

  • Article
  • Open Access
7 Citations
4,636 Views
20 Pages

Comparison of Single Cell Transcriptome Sequencing Methods: Of Mice and Men

  • Bastian V. H. Hornung,
  • Zakia Azmani,
  • Alexander T. den Dekker,
  • Edwin Oole,
  • Zeliha Ozgur,
  • Rutger W. W. Brouwer,
  • Mirjam C. G. N. van den Hout and
  • Wilfred F. J. van IJcken

16 December 2023

Single cell RNAseq has been a big leap in many areas of biology. Rather than investigating gene expression on a whole organism level, this technology enables scientists to get a detailed look at rare single cells or within their cell population of in...

  • Article
  • Open Access
29 Citations
4,181 Views
22 Pages

9 October 2022

Dendrobium huoshanense, Dendrobium officinale, and Dendrobium moniliforme, as precious Chinese medicinal materials, have a variety of medicinal properties. Flavonoids are important medicinal components of Dendrobium, but their accumulation rules and...

  • Article
  • Open Access
28 Citations
5,450 Views
12 Pages

Transcriptome and Hormone Comparison of Three Cytoplasmic Male Sterile Systems in Brassica napus

  • Bingli Ding,
  • Mengyu Hao,
  • Desheng Mei,
  • Qamar U Zaman,
  • Shifei Sang,
  • Hui Wang,
  • Wenxiang Wang,
  • Li Fu,
  • Hongtao Cheng and
  • Qiong Hu

12 December 2018

The interaction between plant mitochondria and the nucleus markedly influences stress responses and morphological features, including growth and development. An important example of this interaction is cytoplasmic male sterility (CMS), which results...

  • Article
  • Open Access
7 Citations
5,633 Views
13 Pages

15 June 2020

Nuptial plumage coloration is critical in the mating choice of the crested ibis. This species has a characteristic nuptial plumage that develops from the application of a black sticky substance, secreted by a patch of skin in the throat and neck regi...

  • Article
  • Open Access
13 Citations
4,057 Views
15 Pages

Transcriptome Comparison Reveals the Difference in Liver Fat Metabolism between Different Sheep Breeds

  • Taotao Li,
  • Meilin Jin,
  • Xiaojuan Fei,
  • Zehu Yuan,
  • Yuqin Wang,
  • Kai Quan,
  • Tingpu Wang,
  • Junxiang Yang,
  • Maochang He and
  • Caihong Wei

27 June 2022

Hu sheep and Tibetan sheep are two commonly raised local sheep breeds in China, and they have different morphological characteristics, such as tail type and adaptability to extreme environments. A fat tail in sheep is the main adipose depot in sheep,...

  • Article
  • Open Access
2,332 Views
16 Pages

Comparison of the Effect of Pruning on Plant Growth and Transcriptome Profiles in Different Tea Varieties

  • Shizhuo Kan,
  • Dandan Tang,
  • Lufang Feng,
  • Xiaoqin Tan,
  • Yijing Zhang and
  • Qian Tang

23 May 2024

Although pruning contributes to the growth and development of new shoots, it is important to note that the growth potential and yield of tea varieties may differ after pruning due to genetic and environmental factors. In this experiment, 20 different...

  • Article
  • Open Access
26 Citations
6,373 Views
19 Pages

Transcriptome Signatures of Canine Mammary Gland Tumors and Its Comparison to Human Breast Cancers

  • Kang-Hoon Lee,
  • Hyoung-Min Park,
  • Keun-Hong Son,
  • Tae-Jin Shin and
  • Je-Yoel Cho

7 September 2018

Breast cancer (BC)/mammary gland carcinoma (MGC) is the most frequently diagnosed and leading cause of cancer-related mortality in both women and canines. To better understand both canine MGC and human BC-specific genes, we sequenced RNAs obtained fr...

  • Article
  • Open Access
14 Citations
3,735 Views
16 Pages

23 November 2020

Bamboo plants have a distinctive life cycle with long flowering periodicity. Many species remain in vegetative growth for decades, followed by large-scale flowering and subsequent death. Floral transition is activated while shoot buds are still dorma...

  • Feature Paper
  • Article
  • Open Access
11 Citations
3,425 Views
11 Pages

The Effect of Human and Bovine Milk Osteopontin on Intestinal Caco-2 Cells: A Transcriptome Comparison

  • Brian Christensen,
  • Albert J. Buitenhuis,
  • Lotte N. Jacobsen,
  • Marie S. Ostenfeld and
  • Esben S. Sørensen

25 February 2023

Osteopontin (OPN) is a multifunctional protein abundantly present in human milk, whereas the concentration is significantly lower in bovine milk. Human and bovine milk OPN are structurally similar and both proteins resist gastric digestion and reach...

  • Article
  • Open Access
3 Citations
2,755 Views
14 Pages

Comparison between the Gametophyte and the Sporophyte Transcriptomes of the Endangered Fern Vandenboschia speciosa

  • Rubén Martín-Blázquez,
  • Mohammed Bakkali,
  • Mercedes Ruiz-Estévez and
  • Manuel A. Garrido-Ramos

7 January 2023

Genomic resources are essential to understanding the evolution and functional biology of organisms. Nevertheless, generating genomic resources from endangered species may be challenging due to the scarcity of available specimens and sampling difficul...

  • Article
  • Open Access
7 Citations
4,729 Views
21 Pages

12 October 2019

Gnetum possesses morphologically bisexual but functionally unisexual reproductive structures that exude sugary pollination drops to attract insects. Previous studies have revealed that the arborescent species (G. gnemon L.) and the lianoid species (G...

  • Article
  • Open Access
10 Citations
3,408 Views
14 Pages

Identification and Comparison of Hyperglycemia-Induced Extracellular Vesicle Transcriptome in Different Mouse Stem Cells

  • Grace Huang,
  • Venkata Naga Srikanth Garikipati,
  • Yan Zhou,
  • Cynthia Benedict,
  • Steven R. Houser,
  • Walter J. Koch and
  • Raj Kishore

15 September 2020

Extracellular vesicles (EVs) derived from stem /progenitor cells harbor immense potential to promote cardiomyocyte survival and neovascularization, and to mitigate ischemic injury. However, EVs’ parental stem/progenitor cells showed modest bene...

  • Article
  • Open Access
27 Citations
5,008 Views
15 Pages

Comparison of Transcriptome Differences in Soybean Response to Soybean Mosaic Virus under Normal Light and in the Shade

  • Lei Zhang,
  • Jing Shang,
  • Wenming Wang,
  • Junbo Du,
  • Kai Li,
  • Xiaoling Wu,
  • Liang Yu,
  • Chunyan Liu,
  • Muhammad Ibrahim Khaskheli and
  • Wenyu Yang

29 August 2019

Shading in the intercropping system is a major abiotic factor which influences soybean growth and development, while soybean mosaic virus (SMV) is a biotic factor that limits the yield and quality of soybean. However, little is known about the defens...

  • Article
  • Open Access
5 Citations
3,454 Views
15 Pages

Normalized Workflow to Optimize Hybrid De Novo Transcriptome Assembly for Non-Model Species: A Case Study in Lilium ledebourii (Baker) Boiss

  • Morteza Sheikh-Assadi,
  • Roohangiz Naderi,
  • Seyed Alireza Salami,
  • Mohsen Kafi,
  • Reza Fatahi,
  • Vahid Shariati,
  • Federico Martinelli,
  • Angela Cicatelli,
  • Maria Triassi and
  • Manuel Gonzalo Claros
  • + 2 authors

10 September 2022

A high-quality transcriptome is required to advance numerous bioinformatics workflows. Nevertheless, the effectuality of tools for de novo assembly and real precision assembled transcriptomes looks somewhat unexplored, particularly for non-model orga...

  • Article
  • Open Access
4 Citations
3,952 Views
17 Pages

24 October 2021

Lichen secondary metabolites are natural products of high medicinal and industrial value, which are produced by the fungal symbiont (mycobiont) of lichens in response to environmental changes. It has been shown that the cultured mycobiont is capable...

  • Article
  • Open Access
4 Citations
2,152 Views
16 Pages

Comparison of Transcriptome Differences between Two Rice Cultivars Differing in Cadmium Translocation from Spike-Neck to Grain

  • Shouping Zhao,
  • Qi Zhang,
  • Wendan Xiao,
  • De Chen,
  • Jing Hu,
  • Na Gao,
  • Miaojie Huang and
  • Xuezhu Ye

At present, the mechanism of varietal differences in cadmium (Cd) accumulation in rice is not well understood. Two rice cultivars, ZZY (high translocation-high grain Cd) and SJ18 (low translocation-low grain Cd), were used to analyze transcriptome di...

  • Article
  • Open Access
10 Citations
3,694 Views
16 Pages

Chromosome-Level Genome Assembly and Transcriptome Comparison Analysis of Cephalopholis sonnerati and Its Related Grouper Species

  • Zhenzhen Xie,
  • Dengdong Wang,
  • Shoujia Jiang,
  • Cheng Peng,
  • Qing Wang,
  • Chunren Huang,
  • Shuisheng Li,
  • Haoran Lin and
  • Yong Zhang

13 July 2022

The tomato hind, Cephalopholis sonnerati, is a bottom-dwelling coral reef fish, which is widely distributed in the Indo-Pacific and Red Sea. C. sonnerati also features complex social structures and behaviour mechanisms. Here, we present a high-qualit...

  • Article
  • Open Access
1,136 Views
20 Pages

6 April 2025

The diversity of skin colors observed in reptiles is indicative of their adaptation to different ecological niches, with these color variations playing essential roles in survival and reproduction. The present study focused on two closely related spe...

  • Article
  • Open Access
7 Citations
4,292 Views
24 Pages

5 February 2020

Porcine reproductive and respiratory syndrome virus (PRRSV) is a major respiratory pathogen of swine that has become extremely costly to the swine industry worldwide, often causing losses in production and animal life due to their ease of spread. How...

  • Article
  • Open Access
19 Citations
6,723 Views
25 Pages

Mammalian and Invertebrate Models as Complementary Tools for Gaining Mechanistic Insight on Muscle Responses to Spaceflight

  • Thomas Cahill,
  • Henry Cope,
  • Joseph J. Bass,
  • Eliah G. Overbey,
  • Rachel Gilbert,
  • Willian Abraham da Silveira,
  • Amber M. Paul,
  • Tejaswini Mishra,
  • Raúl Herranz and
  • Candice G. T. Tahimic
  • + 4 authors

31 August 2021

Bioinformatics approaches have proven useful in understanding biological responses to spaceflight. Spaceflight experiments remain resource intensive and rare. One outstanding issue is how to maximize scientific output from a limited number of omics d...

  • Article
  • Open Access
6 Citations
2,345 Views
19 Pages

Role of SiPHR1 in the Response to Low Phosphate in Foxtail Millet via Comparative Transcriptomic and Co-Expression Network Analyses

  • Guofang Xing,
  • Minshan Jin,
  • Peiyao Yue,
  • Chao Ren,
  • Jiongyu Hao,
  • Yue Zhao,
  • Xiongwei Zhao,
  • Zhaoxia Sun and
  • Siyu Hou

14 August 2023

Enhancing the absorption and utilization of phosphorus by crops is an important aim for ensuring food security worldwide. However, the gene regulatory network underlying phosphorus use in foxtail millet remains unclear. In this study, the molecular m...

  • Article
  • Open Access
3 Citations
4,223 Views
25 Pages

Comparative Transcriptomics of Multi-Stress Responses in Pachycladon cheesemanii and Arabidopsis thaliana

  • Yanni Dong,
  • Saurabh Gupta,
  • Jason J. Wargent,
  • Joanna Putterill,
  • Richard C. Macknight,
  • Tsanko S. Gechev,
  • Bernd Mueller-Roeber and
  • Paul P. Dijkwel

The environment is seldom optimal for plant growth and changes in abiotic and biotic signals, including temperature, water availability, radiation and pests, induce plant responses to optimise survival. The New Zealand native plant species and close...

  • Article
  • Open Access
6 Citations
6,794 Views
14 Pages

3 December 2019

The comparison of high throughput gene expression datasets obtained from different experimental conditions is a challenging task. It provides an opportunity to explore the cellular response to various biological events such as disease, environmental...

  • Article
  • Open Access
8 Citations
4,361 Views
18 Pages

Effect of Transgenesis on mRNA and miRNA Profiles in Cucumber Fruits Expressing Thaumatin II

  • Magdalena Ewa Pawełkowicz,
  • Agnieszka Skarzyńska,
  • Małgorzata Sroka,
  • Maria Szwacka,
  • Tomasz Pniewski and
  • Wojciech Pląder

20 March 2020

Transgenic plants are commonly used in breeding programs because of the various features that can be introduced. However, unintended effects caused by genetic transformation are still a topic of concern. This makes research on the nutritional safety...

  • Article
  • Open Access
10 Citations
11,607 Views
20 Pages

Comparison of Transcriptome between Tolerant and Susceptible Rice Cultivar Reveals Positive and Negative Regulators of Response to Rhizoctonia solani in Rice

  • Xiurong Yang,
  • Shuangyong Yan,
  • Yuejiao Li,
  • Guangsheng Li,
  • Shuqin Sun,
  • Junling Li,
  • Zhongqiu Cui,
  • Jianfei Huo,
  • Yue Sun and
  • Fangzhou Liu
  • + 1 author

20 September 2023

Rice (Oryza sativa L.) is one of the world’s most crucial food crops, as it currently supports more than half of the world’s population. However, the presence of sheath blight (SB) caused by Rhizoctonia solani has become a significant iss...

  • Article
  • Open Access
1 Citations
2,101 Views
21 Pages

Transcriptome and Functional Comparison of Primary and Immortalized Endothelial Cells of the Human Choroid Plexus at the Blood–Cerebrospinal Fluid Barrier

  • Lea Denzer,
  • Walter Muranyi,
  • Rosanna Herold,
  • Carolin Stump-Guthier,
  • Hiroshi Ishikawa,
  • Carsten Sticht,
  • Horst Schroten,
  • Christian Schwerk and
  • Stefan Weichert

19 February 2025

The human choroid plexus (CP) is the location of the blood–cerebrospinal fluid (CSF) barrier (BCSFB). Whereas the epithelial cells of the CP mainly contribute to the formation of the BCSFB, the vessels of the CP are built by fenestrated endothe...

  • Article
  • Open Access
8 Citations
4,715 Views
9 Pages

Analysis of RNA-sequencing (RNA-seq) data is an effective means to analyze the gene expression levels under specific conditions and discover new biological knowledge. More than 74,000 experimental series with RNA-seq have been stored in public databa...

  • Article
  • Open Access
2 Citations
2,933 Views
17 Pages

Global Transcriptomic and Characteristics Comparisons between Mouse Fetal Liver and Bone Marrow Definitive Erythropoiesis

  • Chengjie Gao,
  • Huan Zhang,
  • Yaomei Wang,
  • Shihui Wang,
  • Xinhua Guo,
  • Yongshuai Han,
  • Huizhi Zhao and
  • Xiuli An

5 July 2024

Erythropoiesis occurs first in the yolk sac as a transit “primitive” form, then is gradually replaced by the “definitive” form in the fetal liver (FL) during fetal development and in the bone marrow (BM) postnatally. While it...

  • Article
  • Open Access
3 Citations
2,908 Views
19 Pages

Comparison of Growth Performance, Nutritional Composition, and Muscle Transcriptome between Two Cultured Varieties of the Chinese Mitten Crab (Eriocheir sinensis)

  • Ziyu Wang,
  • Peiying Huang,
  • Xiaoyong Li,
  • Jianmin Pei,
  • Wenzhen Liu,
  • Jiahao Hou,
  • Linjie Li,
  • Hongxiang Fan,
  • Liugen Zeng and
  • Daxian Zhao

9 April 2024

This study evaluated the disparities in growth performance and nutritional composition between two common Chinese mitten crab varieties, “Jianghai 21” and “Changjiang 2”, cultured in Jiangxi Province. Over the breeding period,...

  • Feature Paper
  • Article
  • Open Access
36 Citations
7,681 Views
12 Pages

Plant diseases caused by viral infection are affecting all major crops. Being an obligate intracellular organisms, chemical control of these pathogens is so far not applied in the field except to control the insect vectors of the viruses. Understandi...

  • Article
  • Open Access
3 Citations
3,554 Views
13 Pages

19 July 2021

The Green-legged Partridgelike fowl is a native, dual-purpose Polish chicken. The White Leghorn has been intensively selected for several decades to mainly improve reproductive traits. Primordial germ cells (PGCs) represent the germline stem cells in...

  • Article
  • Open Access
6 Citations
3,827 Views
17 Pages

Comparison between the Transcriptomes of ‘KDML105’ Rice and a Salt-Tolerant Chromosome Segment Substitution Line

  • Nopphawitchayaphong Khrueasan,
  • Panita Chutimanukul,
  • Kitiporn Plaimas,
  • Teerapong Buaboocha,
  • Meechai Siangliw,
  • Theerayut Toojinda,
  • Luca Comai and
  • Supachitra Chadchawan

24 September 2019

‘KDML105’ rice, known as jasmine rice, is grown in northeast Thailand. The soil there has high salinity, which leads to low productivity. Chromosome substitution lines (CSSLs) with the ‘KDML105’ rice genetic background were ev...

  • Article
  • Open Access
4 Citations
3,093 Views
23 Pages

11 September 2022

Mesobuthus martensii, a famous and important Traditional Chinese Medicine has a long medical history and unique functions. It is the first scorpion species whose whole genome was sequenced worldwide. In addition, it is the most widespread and infamou...

  • Article
  • Open Access
2 Citations
2,253 Views
18 Pages

10 February 2024

Oocytes are efficient at reprogramming terminally differentiated cells to a totipotent state. Nuclear transfer techniques can exploit this property to produce cloned animals. However, the overall efficiency is low. The use of umbilical cord mesenchym...

  • Article
  • Open Access
8 Citations
4,348 Views
18 Pages

29 May 2020

Jao Hom Nin (JHN) is a Thai rice variety with broad-spectrum resistant against rice blast fungus. JHN contains two rice blast resistant genes, Pish and Pik, located on chromosome 1 and on chromosome 11, respectively. To understand the blast resistanc...

  • Article
  • Open Access
11 Citations
3,695 Views
14 Pages

31 August 2021

Glaucoma is a leading cause of blindness and is characterized by the progressive dysfunction and irreversible death of retinal ganglion cells. We aimed to identify shared differentially expressed genes (DE genes) between different glaucoma relevant m...

  • Article
  • Open Access
35 Citations
7,363 Views
11 Pages

Uncovering drug-target interactions (DTIs) is pivotal to understand drug mode-of-action (MoA), avoid adverse drug reaction (ADR), and seek opportunities for drug repositioning (DR). For decades, in silico predictions for DTIs have largely depended on...

  • Article
  • Open Access
24 Citations
4,650 Views
14 Pages

31 March 2020

Production of nickel (Ni) and nickel oxide (NiO) nanoparticles (NPs) leads to a risk of exposure and subsequent health effects. Understanding the toxicological effects and underlying mechanisms using relevant in vitro methods is, therefore, needed. T...

  • Article
  • Open Access
8 Citations
5,203 Views
18 Pages

29 January 2022

High-cost milk proteins necessitate cheaper, effective milk replacer alternatives, such as plant proteins. To examine plant protein-based milk replacer’s impact on growth performance, serum immune and antioxidant indicators, and liver transcrip...

  • Article
  • Open Access
724 Views
15 Pages

Altered Transcriptome Signature in Primary Human Myotubes Exposed to Inclusion Body Myositis Serum: A Pilot Case Comparison of Anti-cN1A Positive and Negative Sera

  • Nataliya Slater,
  • Abha Chopra,
  • Ramesh Ram,
  • Abbie Adams,
  • Frank L. Mastaglia,
  • Merrilee Needham and
  • Jerome D. Coudert

10 November 2025

Inclusion body myositis (IBM) is a late-onset, treatment-resistant inflammatory myopathy. Approximately half of IBM patients develop autoantibodies against cytosolic 5-nucleotidase 1A (cN1A), but their role in disease pathogenesis remains uncl...

  • Article
  • Open Access
3 Citations
3,142 Views
35 Pages

22 December 2024

Ultraviolet C (UV-C) flash treatment represents a promising method for priming plants. This study compared the effects of 1 s (flash) and 60 s (60 s) UV-C exposures on the transcriptome of Arabidopsis thaliana L. plants. A dose of 200 J m−2 del...

  • Article
  • Open Access
55 Citations
6,492 Views
18 Pages

Purple-leaf tea is a phenotype with unique color because of its high anthocyanin content. The special flavor of purple-leaf tea is highly different from that of green-leaf tea, and its main ingredient is also of economic value. To probe the genetic m...

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