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2,737 Results Found

  • Article
  • Open Access
663 Views
13 Pages

The Liquid Guide System: Design and Clinical Feasibility of an Internally Irrigated 3D-Printed Surgical Guide for Implant Surgery

  • Adrian Teodor Moga-Rogoz,
  • Tudor Matei,
  • Mihaela Hedeșiu,
  • Mihaela Băciuț and ,
  • Sorana Eftimie and
  • Marius Steigmann
  • + 1 author+ 0 author

13 July 2026

Background/Objectives: Thermal injury during implant osteotomy is a recognized complication of guided surgery. Closed guide architectures and metallic sleeves restrict coolant access to the drill–bone interface, reducing the effectiveness of co...

(This article belongs to the Special Issue Dental Implantology: Clinical Updates and Perspectives—2nd Edition)
  • Article
  • Open Access
27 Citations
8,756 Views
13 Pages

Stereolithographic Surgical Guide with a Combination of Tooth and Bone Support: Accuracy of Guided Implant Surgery in Distal Extension Situation

  • Chia-Cheng Lin,
  • Masahiro Ishikawa,
  • Takeo Maida,
  • Hsin-Chung Cheng and ,
  • Keng-Liang Ou,
  • Takashi Nezu and
  • Kazuhiko Endo
  • + 2 authors+ 0 author

A distal free-end situation could result in insufficient stability of the surgical guide, and could reduce accuracy of the static guided implant surgery (sGIS). The purpose of this study was to investigate the accuracy of sGIS using a combination too...

(This article belongs to the Special Issue Advances in Digital Dentistry: From Data Acquisition to Data Production)
  • Article
  • Open Access
16 Citations
7,265 Views
11 Pages

A Bone-Thickness Map as a Guide for Bone-Anchored Port Implantation Surgery in the Temporal Bone

  • Jérémie Guignard,
  • Andreas Arnold,
  • Christian Weisstanner,
  • Marco Caversaccio and
  • Christof Stieger

19 November 2013

The bone-anchored port (BAP) is an investigational implant, which is intended to be fixed on the temporal bone and provide vascular access. There are a number of implants taking advantage of the stability and available room in the temporal bone. Thes...

(This article belongs to the Special Issue Computational Modeling and Simulation in Materials Study)
  • Article
  • Open Access
6 Citations
3,253 Views
13 Pages

Customised 3D-Printed Surgical Guide for Breast-Conserving Surgery after Neoadjuvant Chemotherapy and Its Clinical Application

  • Jie Luo,
  • Feng Chen,
  • Hong Cao,
  • Wei Zhu and ,
  • Jian Deng,
  • Dan Li,
  • Wei Li,
  • Junjie Deng,
  • Yangyan Zhong and
  • Jiaren Chen
  • + 9 authors+ 4 authors

For patients eligible to undergo breast-conserving surgery (BCS) after neoadjuvant chemotherapy, accurate preoperative localisation of tumours is vital to ensure adequate tumour resection that can reduce recurrence probability effectively. For this r...

(This article belongs to the Section Regenerative Engineering)
  • Article
  • Open Access
7 Citations
6,471 Views
16 Pages

A Novel Approach to Guided Implant Surgery: A Technical Note

  • Federico Franchini,
  • Massimo Fuzzi,
  • Renato Leone and
  • Roberto Sorrentino

23 September 2022

Computer-guided software and kits have significantly improved the clinical applications of implant surgery. Nonetheless, some technical problems are still in evidence during clinical procedures because of cumbersome surgical tools that can limit acce...

(This article belongs to the Section Prosthodontics)
  • Article
  • Open Access
3 Citations
4,843 Views
14 Pages

13 March 2020

The aim of this study is to compare the implant placement deviations and evaluate the 1-year post-implant placement bone loss of pilot and fully guided implant placement protocols. In the first method, the pilot drill is used for guide surgery, and t...

(This article belongs to the Special Issue Application of CAD/CAM and 3D Printing Technologies in Dentistry)
  • Article
  • Open Access
10 Citations
3,816 Views
7 Pages

Accuracy of Guided Surgery and Real-Time Navigation in Temporomandibular Joint Replacement Surgery

  • Michael-Tobias Neuhaus,
  • Alexander-Nicolai Zeller,
  • Alexander K. Bartella,
  • Anna K. Sander and ,
  • Bernd Lethaus and
  • Rüdiger M. Zimmerer
  • + 1 author+ 0 author

2 August 2021

Background: Sophisticated guided surgery has not been implemented into total joint replacement-surgery (TJR) of the temporomandibular joint (TMJ) so far. Design and in-house manufacturing of a new advanced drilling guide with vector and length contro...

(This article belongs to the Section Digital Technologies)
  • Review
  • Open Access
37 Citations
5,749 Views
24 Pages

Fluorescence Image-Guided Surgery for Thyroid Cancer: Utility for Preventing Hypoparathyroidism

  • Marco Stefano Demarchi,
  • Barbara Seeliger,
  • Jean-Christophe Lifante,
  • Pier Francesco Alesina and
  • Frédéric Triponez

28 July 2021

Background: Hypoparathyroidism is one of the most frequent complications of thyroid surgery, especially when associated with lymph node dissection in cases of thyroid cancer. Fluorescence-guided surgery is an emerging tool that appears to help reduce...

(This article belongs to the Special Issue Advances in the Diagnosis and Treatment of Thyroid Carcinoma)
  • Systematic Review
  • Open Access
10 Citations
5,820 Views
24 Pages

Efficacy and Safety of Fluorescence-Guided Surgery Compared to Conventional Surgery in the Management of Colorectal Cancer: A Systematic Review and Meta-Analysis

  • Michael G. Fadel,
  • Elham Zonoobi,
  • María Rita Rodríguez-Luna,
  • Kohei Mishima and ,
  • Frédéric Ris,
  • Michele Diana,
  • Alexander L. Vahrmeijer,
  • Silvana Perretta,
  • Hutan Ashrafian and
  • Matyas Fehervari
  • + 5 authors+ 0 author

2 October 2024

Background: The use of fluorescence agents and imaging systems is a promising adjunct in the surgical management of colorectal cancer. This systematic review and meta-analysis aimed to assess the safety and efficacy of fluorescence-guided surgery in...

(This article belongs to the Section Systematic Review or Meta-Analysis in Cancer Research)
  • Article
  • Open Access
1 Citations
1,147 Views
12 Pages

30 November 2025

Background: Thoracic paravertebral block (TPVB) is an established component of multimodal analgesia and enhanced recovery pathways following thoracoscopic lung resection. A surgeon-performed, thoracoscopy-guided approach has been proposed to improve...

(This article belongs to the Special Issue Cardiothoracic Surgery and Enhanced Recovery: Recent Advances and Perspectives)
  • Article
  • Open Access
1 Citations
2,002 Views
20 Pages

Design and Simulate Intracranial Support to Guide Maxillo Surgery: A Study Based on Bioengineering

  • Maria Giulia Cristofaro,
  • Elvis Kallaverja,
  • Francesco Ferragina and
  • Ida Barca

14 December 2023

Background: Intraoperative navigation allows for the creation of a real-time relationship between the anatomy imagined during diagnosis/planning and the site of surgical interest. This procedure takes place by identifying and registering trustworthy...

(This article belongs to the Section Point-of-Care Diagnostics and Devices)
  • Review
  • Open Access
4 Citations
2,060 Views
11 Pages

Radio-Guided Lung Surgery: A Feasible Approach for a Cancer Precision Medicine

  • Miriam Conte,
  • Maria Silvia De Feo,
  • Viviana Frantellizzi,
  • Miriam Tomaciello and ,
  • Francesco Marampon,
  • Laura Evangelista,
  • Luca Filippi and
  • Giuseppe De Vincentis
  • + 3 authors+ 0 author

Background: Radio-guided surgery is a reliable approach used for localizing ground-glass opacities, lung nodules, and metastatic lymph nodes. Lung nodules, lymph node metastatic involvement, and ground-glass opacities often represent a challenge for...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
19 Citations
7,735 Views
23 Pages

A Vision-Guided Robotic System for Safe Dental Implant Surgery

  • Daria Pisla,
  • Vasile Bulbucan,
  • Mihaela Hedesiu,
  • Calin Vaida and ,
  • Ionut Zima,
  • Rares Mocan,
  • Paul Tucan,
  • Cristian Dinu,
  • Doina Pisla and
  • TEAM Project Group
  • + 5 authors+ 0 author

23 October 2024

Background: Recent advancements in dental implantology have significantly improved outcomes, with success rates of 90–95% over a 10-year period. Key improvements include enhanced preplanning processes, such as precise implant positioning, model...

(This article belongs to the Special Issue Research Progress in Osseointegrated Oral Implants)
  • Article
  • Open Access
1 Citations
5,554 Views
13 Pages

Evaluation of EphB4 as Target for Image-Guided Surgery of Breast Cancer

  • Cansu de Muijnck,
  • Yoren van Gorkom,
  • Maurice van Duijvenvoorde,
  • Mina Eghtesadi and ,
  • Geeske Dekker-Ensink,
  • Shadhvi S. Bhairosingh,
  • Alessandra Affinito,
  • Peter J. K. Kuppen,
  • Alexander L. Vahrmeijer and
  • Cornelis F. M. Sier
  • + 5 authors+ 0 author

Background: Targeted image-guided surgery is based on the detection of tumor cells after administration of a radio-active or fluorescent tracer. Hence, enhanced binding of a tracer to tumor tissue compared to healthy tissue is crucial. Various tumor...

(This article belongs to the Special Issue Targeting the Eph–ephrin System)
  • Article
  • Open Access
8 Citations
4,328 Views
12 Pages

Waferless Orthognathic Surgery with Customized Osteosynthesis and Surgical Guides: A Prospective Study

  • Marc Espino-Segura-Illa,
  • Octavi Camps-Font,
  • Ada Ferrer-Fuertes,
  • Fran Cuesta-González and ,
  • Ignacio Zubillaga-Rodríguez and
  • Ramón Sieira-Gil
  • + 1 author+ 0 author

25 February 2024

The purpose of this paper was to describe and to evaluate the accuracy of a protocol that involves CAD/CAM-generated cutting guides and customized titanium plates for waferless orthognathic surgery. Twenty-one patients consecutively treated between J...

  • Review
  • Open Access
18 Citations
11,591 Views
15 Pages

Accuracy of Different Systems of Guided Implant Surgery and Methods for Quantification: A Systematic Review

  • Nataly Marquez Bautista,
  • Cristina Meniz-García,
  • Carmen López-Carriches,
  • Luis Sánchez-Labrador and ,
  • Jorge Cortés-Bretón Brinkmann and
  • Cristina Madrigal Martínez-Pereda
  • + 1 author+ 0 author

10 December 2024

The aim of this systematic review was to assess the scientific literature on the accuracy of guided implant surgery and the methods used for its quantification. Two reviewers searched PubMed and the Cochrane Library to identify relevant articles publ...

(This article belongs to the Special Issue Recent Advances in Digital Dentistry and Oral Implantology)
  • Review
  • Open Access
11 Citations
5,613 Views
17 Pages

Advances in Ultrasound-Guided Surgery and Artificial Intelligence Applications in Musculoskeletal Diseases

  • Soichi Hattori,
  • Rachit Saggar,
  • Eva Heidinger,
  • Andrew Qi and ,
  • Joseph Mullen,
  • Brianna Fee,
  • Cortez L. Brown,
  • Stephen P. Canton,
  • Devon Scott and
  • MaCalus V. Hogan
  • + 5 authors+ 0 author

11 September 2024

Ultrasound imaging is a vital imaging tool in musculoskeletal medicine, with the number of publications on ultrasound-guided surgery increasing in recent years, especially in minimally invasive procedures of sports, foot and ankle, and hand surgery....

(This article belongs to the Special Issue Imaging of Musculoskeletal Diseases: New Advances and Future Trends)
  • Article
  • Open Access
15 Citations
3,925 Views
11 Pages

Implant Treatment by Guided Surgery Supporting Overdentures in Edentulous Mandible Patients

  • Eugenio Velasco-Ortega,
  • Alvaro Jiménez-Guerra,
  • Ivan Ortiz-Garcia,
  • Nuno Matos Garrido and ,
  • Jesús Moreno-Muñoz,
  • Enrique Núñez-Márquez,
  • José Luis Rondón-Romero,
  • Daniel Cabanillas-Balsera,
  • José López-López and
  • Loreto Monsalve-Guil
  • + 5 authors+ 0 author

Introduction: This study aimed to show the clinical outcomes of implants inserted by guided surgery supporting mandibular overdentures in edentulous patients. Patients and methods: Mandibular edentulous patients were diagnosed with an oral examinatio...

(This article belongs to the Special Issue Digital Dentistry, Implantology and Maxillo-Facial Diseases)
  • Article
  • Open Access
18 Citations
5,566 Views
10 Pages

Accuracy of Guided Implant Surgery in the Edentulous Jaw Using Desktop 3D-Printed Mucosal Supported Guides

  • Rani D’haese,
  • Tom Vrombaut,
  • Geert Hommez,
  • Hugo De Bruyn and
  • Stefan Vandeweghe

20 January 2021

Purpose: The aim of this in vitro study is to evaluate the accuracy of implant position using mucosal supported surgical guides, produced by a desktop 3D printer. Methods: Ninety implants (Bone Level Roxolid, 4.1 mm × 10 mm, Straumann, Villerat...

(This article belongs to the Special Issue Clinical Advances in Implant Dentistry)
  • Review
  • Open Access
49 Citations
11,308 Views
19 Pages

NIR-II Fluorescent Probes for Fluorescence-Imaging-Guided Tumor Surgery

  • Zia Ullah,
  • Shubham Roy,
  • Jingshi Gu,
  • Sai Ko Soe and ,
  • Jian Jin and
  • Bing Guo
  • + 1 author+ 0 author

30 May 2024

Second near-infrared (NIR-II) fluorescence imaging is the most advanced imaging fidelity method with extraordinary penetration depth, signal-to-background ratio, biocompatibility, and targeting ability. It is currently booming in the medical realm to...

(This article belongs to the Section Optical and Photonic Biosensors)
  • Article
  • Open Access
64 Citations
12,291 Views
15 Pages

Fully Digital Workflow for Planning Static Guided Implant Surgery: A Prospective Accuracy Study

  • Chia-Cheng Lin,
  • Ching-Zong Wu,
  • Mao-Suan Huang,
  • Chiung-Fang Huang and ,
  • Hsin-Chung Cheng and
  • Dayen Peter Wang
  • + 1 author+ 0 author

The accuracy of static guided implant surgery (sGIS) using conventional planning workflow has been extensively examined; however, more information is required to justify the application of fully digital planning protocol. The purpose of this study wa...

(This article belongs to the Special Issue Advances in Digital Dentistry: From Data Acquisition to Data Production)
  • Review
  • Open Access
12 Citations
3,734 Views
19 Pages

5 April 2023

Fluorescence-guided surgery (FGS) is used in many pediatric subspecialties but there are currently no standard guidelines or outcome data. We aimed to assess the current status of FGS in pediatrics using the Idea, Development, Exploration, Assessment...

(This article belongs to the Section Pediatric Surgery)
  • Case Report
  • Open Access
7 Citations
3,003 Views
6 Pages

Fluorescence-Guided Surgery (FGS) during a Laparoscopic Redo Nissen Fundoplication: The First Case in Children

  • Irene Paraboschi,
  • Laura Privitera,
  • Stavros Loukogeorgakis and
  • Stefano Giuliani

We present the first case of fluorescence-guided surgery (FGS) using indocyanine green (ICG) in a pediatric redo-Nissen fundoplication. The patient is a 17-year-old male with recurrent gastroesophageal symptoms who underwent primary antireflux surger...

(This article belongs to the Special Issue Advance in Pediatric Surgery)
  • Review
  • Open Access
30 Citations
5,766 Views
13 Pages

New Intraoperative Imaging Tools and Image-Guided Surgery in Gastric Cancer Surgery

  • Luise Knospe,
  • Ines Gockel,
  • Boris Jansen-Winkeln,
  • René Thieme and ,
  • Stefan Niebisch,
  • Yusef Moulla,
  • Sigmar Stelzner,
  • Orestis Lyros,
  • Michele Diana and
  • Han-Kwang Yang
  • + 11 authors+ 6 authors

16 February 2022

Innovations and new advancements in intraoperative real-time imaging have gained significant importance in the field of gastric cancer surgery in the recent past. Currently, the most promising procedures include indocyanine green fluorescence imaging...

(This article belongs to the Section Biomedical Optics)
  • Article
  • Open Access
12 Citations
4,568 Views
15 Pages

In Vitro Accuracy of Static Guided Implant Surgery Measured by Optical Scan: Examining the Impact of Operator Experience

  • Chia-Cheng Lin,
  • Masahiro Ishikawa,
  • Bai-Hung Huang,
  • Mao-Suan Huang and ,
  • Hsin-Chung Cheng,
  • Takeo Maida,
  • Takashi Nezu and
  • Kazuhiko Endo
  • + 3 authors+ 0 author

15 April 2020

Studies examining the effect of operator experience on the accuracy of static guided implant surgery have used postoperative computed tomography (CT) images to measure the error, with inconsistent results. The purpose of this study was to try to clar...

(This article belongs to the Special Issue Application of the Biocomposite Materials on Bone Reconstruction)
  • Article
  • Open Access
4 Citations
2,916 Views
11 Pages

The Accuracy of Patient-Specific Spinal Drill Guides Is Non-Inferior to Computer-Assisted Surgery: The Results of a Split-Spine Randomized Controlled Trial

  • Peter A. J. Pijpker,
  • Jos M. A. Kuijlen,
  • Katalin Tamási,
  • D. L. Marinus Oterdoom and ,
  • Rob A. Vergeer,
  • Gijs Rijtema,
  • Maarten H. Coppes,
  • Joep Kraeima and
  • Rob J. M. Groen
  • + 4 authors+ 0 author

30 June 2022

In recent years, patient-specific spinal drill guides (3DPGs) have gained widespread popularity. Several studies have shown that the accuracy of screw insertion with these guides is superior to that obtained using the freehand insertion technique, bu...

  • Article
  • Open Access
2 Citations
1,885 Views
17 Pages

Guided Implant Surgery in Oral Cancer Patients: Initial Clinical Experience from an Academic Point-of-Care Manufacturing Unit

  • Manuel Tousidonis,
  • Jose-Ignacio Salmeron,
  • Santiago Ochandiano,
  • Ruben Perez-Mañanes and ,
  • Estela Gomez-Larren,
  • Elena Aguilera-Jimenez,
  • Carla de Gregorio-Bermejo,
  • Diego Fernández-Acosta,
  • Borja Gonzalez-Moure and
  • Carlos Navarro-Cuellar
  • + 6 authors+ 1 author

12 January 2026

Background and Objectives: Implant-supported rehabilitation after oral cancer surgery remains technically and biologically demanding due to altered anatomy, scar tissue, and prior radiotherapy. Digital workflows and hospital-based point-of-care (POC)...

(This article belongs to the Special Issue Research on Oral and Maxillofacial Surgery)
  • Article
  • Open Access
14 Citations
4,884 Views
26 Pages

9 January 2023

Traditional dental implant surgery has been challenged by the phenomenal progression in computer-assisted surgery (CAS) that we have been witnessing in recent years. Among the computer-aided technologies, computer-aided design and computer-aided manu...

(This article belongs to the Special Issue Computer Assisted Maxillo-Facial Surgery)
  • Article
  • Open Access
10 Citations
4,172 Views
16 Pages

Tumor-Specific Imaging with Angiostamp800 or Bevacizumab-IRDye 800CW Improves Fluorescence-Guided Surgery over Indocyanine Green in Peritoneal Carcinomatosis

  • Véronique Josserand,
  • Claire Bernard,
  • Thierry Michy,
  • Mélanie Guidetti and ,
  • Julien Vollaire,
  • Jean-Luc Coll and
  • Amandine Hurbin
  • + 2 authors+ 0 author

Complete surgical removal of lesions improves survival of peritoneal carcinomatosis and can be enhanced by intraoperative near-infrared fluorescence imaging. Indocyanine green (ICG) is the only near-infrared fluorescent dye approved for clinical use,...

(This article belongs to the Special Issue Advances in Therapeutic Strategies in Gynecological Malignant Tumors)
  • Article
  • Open Access
19 Citations
4,152 Views
16 Pages

Accuracy of DICOM–DICOM vs. DICOM–STL Protocols in Computer-Guided Surgery: A Human Clinical Study

  • Gianmaria D’Addazio,
  • Edit Xhajanka,
  • Tonino Traini,
  • Manlio Santilli and ,
  • Imena Rexhepi,
  • Giovanna Murmura,
  • Sergio Caputi and
  • Bruna Sinjari
  • + 3 authors+ 0 author

22 April 2022

Guided implant surgery can enhance implant placement positioning, increasing predictability and decreasing postoperative complications., To date, the best protocol to be used for template realization is still unknown. Thus, the aim herein was to clin...

(This article belongs to the Special Issue Current Trends and Future Directions in Prosthetic and Implant Dentistry in the Digital Era)
  • Article
  • Open Access
2 Citations
3,292 Views
14 Pages

A Truncated 14-Amino-Acid Myelin Protein-Zero-Targeting Peptide for Fluorescence-Guided Nerve-Preserving Surgery

  • Nataliia Berehova,
  • Maarten P. van Meerbeek,
  • Samaneh Azargoshasb,
  • Danny M. van Willigen and ,
  • Leon J. Slof,
  • Saaedeh Navaei Lavasani,
  • Matthias N. van Oosterom,
  • Fijs W. B. van Leeuwen and
  • Tessa Buckle
  • + 4 authors+ 0 author

Background: The occurrence of accidental nerve damage during surgery and the increasing application of image guidance during head-and-neck surgery have highlighted the need for molecular targeted nerve-sparing interventions. The implementation of suc...

  • Article
  • Open Access
9 Citations
4,092 Views
11 Pages

Ex Vivo Assessment of Tumor-Targeting Fluorescent Tracers for Image-Guided Surgery

  • Fortuné M.K. Elekonawo,
  • Jan Marie de Gooyer,
  • Desirée L. Bos,
  • David M. Goldenberg and ,
  • Otto C. Boerman,
  • Lodewijk A.A. Brosens,
  • Andreas J.A. Bremers,
  • Johannes H.W. de Wilt and
  • Mark Rijpkema
  • + 4 authors+ 0 author

17 April 2020

Image-guided surgery can aid in achieving complete tumor resection. The development and assessment of tumor-targeted imaging probes for near-infrared fluorescence image-guided surgery relies mainly on preclinical models, but the translation to clinic...

  • Case Report
  • Open Access
19 Citations
4,842 Views
9 Pages

Virtual Reality Simulation and Augmented Reality-Guided Surgery for Total Maxillectomy: A Case Report

  • Hee-Jin Kim,
  • Ye-Joon Jo,
  • Jun-Seok Choi,
  • Hyo-Joon Kim and ,
  • In-Seok Park,
  • Jae-Seek You,
  • Ji-Su Oh and
  • Seong-Yong Moon
  • + 3 authors+ 0 author

10 September 2020

With the improvement in computer graphics and sensors, technologies like virtual reality (VR) and augmented reality (AR) have created new possibilities for developing diagnostic and surgical techniques in the field of surgery. VR and AR are the lates...

(This article belongs to the Special Issue Applied Simulation and Experiment Research in Dentistry)
  • Review
  • Open Access
77 Citations
9,174 Views
11 Pages

Augmented Reality and Image-Guided Robotic Liver Surgery

  • Fabio Giannone,
  • Emanuele Felli,
  • Zineb Cherkaoui,
  • Pietro Mascagni and
  • Patrick Pessaux

14 December 2021

Artificial intelligence makes surgical resection easier and safer, and, at the same time, can improve oncological results. The robotic system fits perfectly with these more or less diffused technologies, and it seems that this benefit is mutual. In l...

(This article belongs to the Special Issue Views and Perspectives of Robot-Assisted Liver Surgery)
  • Technical Note
  • Open Access
3 Citations
3 Pages

Guided implant dentistry using computed tomographic (CT) scans, virtual planning software and mucosa-supported surgical templates is an upcoming technology with the potential for more predictable and less invasive implant placement. While generally a...

  • Systematic Review
  • Open Access
1 Citations
2,453 Views
18 Pages

Identifying Molecular Probes for Fluorescence-Guided Surgery in Neuroblastoma: A Systematic Review

  • Megan Hennessy,
  • Jonathan J. Neville,
  • Laura Privitera,
  • Adam Sedgwick and ,
  • John Anderson and
  • Stefano Giuliani
  • + 1 author+ 0 author

24 April 2025

Background/Objectives: Targeted and non-targeted fluorescent molecular probes (FMPs) can be used intra-operatively to visualise tumour tissue. Multiple probes have been clinically approved for fluorescence-guided surgery (FGS) in adult oncology, and...

(This article belongs to the Section Pediatric Surgery)
  • Review
  • Open Access
10 Citations
4,978 Views
15 Pages

Unique Benefits of Tumor-Specific Nanobodies for Fluorescence Guided Surgery

  • Thinzar M. Lwin,
  • Robert M. Hoffman and
  • Michael Bouvet

18 February 2021

Tumor-specific fluorescence labeling is promising for real-time visualization of solid malignancies during surgery. There are a number of technologies to confer tumor-specific fluorescence. Antibodies have traditionally been used due to their versati...

(This article belongs to the Special Issue The Therapeutic and Diagnostic Potential of Nanobodies)
  • Review
  • Open Access
20 Citations
6,246 Views
20 Pages

Fluorescence-Guided Surgery for Gliomas: Past, Present, and Future

  • Benjamin Rodriguez,
  • Cole S. Brown,
  • Jhair Alejandro Colan,
  • Jack Yin Zhang and ,
  • Sakibul Huq,
  • Daniel Rivera,
  • Tirone Young,
  • Tyree Williams,
  • Varun Subramaniam and
  • Constantinos Hadjipanayis
  • + 5 authors+ 0 author

30 May 2025

Background/Objectives: Glioblastoma (GBM) is the most common primary malignant central nervous system tumor, accounting for 50.9% of malignant CNS diagnoses and carrying a median survival of 15 months despite maximal standard therapy. High recurrence...

(This article belongs to the Section Cancer Therapy)
  • Review
  • Open Access
20 Citations
7,565 Views
17 Pages

Introducing Fluorescence-Guided Surgery for Pediatric Ewing, Osteo-, and Rhabdomyosarcomas: A Literature Review

  • Zeger Rijs,
  • Bernadette Jeremiasse,
  • Naweed Shifai,
  • Hans Gelderblom and ,
  • Cornelis F. M. Sier,
  • Alexander L. Vahrmeijer,
  • Fijs W. B. van Leeuwen,
  • Alida F. W. van der Steeg and
  • Michiel A. J. van de Sande
  • + 4 authors+ 0 author

Sarcomas are a rare heterogeneous group of malignant neoplasms of mesenchymal origin which represent approximately 13% of all cancers in pediatric patients. The most prevalent pediatric bone sarcomas are osteosarcoma (OS) and Ewing sarcoma (ES). Rhab...

(This article belongs to the Special Issue Pathogenic Mechanisms and Novel Therapeutic Approaches for Sarcomas)
  • Article
  • Open Access
4 Citations
3,754 Views
15 Pages

Compact and Handheld SiPM-Based Gamma Camera for Radio-Guided Surgery and Medical Imaging

  • Fabio Acerbi,
  • Aramis Raiola,
  • Cyril Alispach,
  • Hossein Arabi and ,
  • Habib Zaidi,
  • Alberto Gola and
  • Domenico Della Volpe
  • + 2 authors+ 0 author

In the continuous pursuit of minimally invasive interventions while ensuring a radical excision of lesions, Radio-Guided Surgery (RGS) has been for years the standard for image-guided surgery procedures, such as the Sentinel Lymph Node biopsy (SLN),...

  • Article
  • Open Access
5 Citations
3,402 Views
14 Pages

The Dual-Targeted Peptide Conjugated Probe for Depicting Residual Nasopharyngeal Carcinoma and Guiding Surgery

  • Wenhui Huang,
  • Zicong He,
  • Xuekang Cai,
  • Jingming Zhang and ,
  • Wei Li,
  • Kun Wang and
  • Shuixing Zhang
  • + 2 authors+ 0 author

5 September 2022

Detecting residual nasopharyngeal carcinoma (rNPC) can be difficult because of the coexistence of occult tumours and post-chemoradiation changes, which poses a challenge for both radiologists and surgeons using current imaging methods. Currently, mol...

(This article belongs to the Special Issue In Vivo Imaging and Sensing of Biomarkers)
  • Article
  • Open Access
16 Citations
5,060 Views
17 Pages

17 February 2023

Rehabilitative dentistry has made enormous progress in recent years, not only due to the advent of new implant-prosthetic methods, but also thanks to new information technologies that support the doctor. This study aims to present a new implant proto...

(This article belongs to the Collection Oral Implantology: Current Aspects and Future Perspectives)
  • Article
  • Open Access
18 Citations
5,787 Views
10 Pages

Immediate Loading of Implants Placed by Guided Surgery in Geriatric Edentulous Mandible Patients

  • Eugenio Velasco-Ortega,
  • Alvaro Jiménez-Guerra,
  • Ivan Ortiz-Garcia,
  • Jesús Moreno-Muñoz and ,
  • Enrique Núñez-Márquez,
  • Daniel Cabanillas-Balsera,
  • José López-López and
  • Loreto Monsalve-Guil
  • + 3 authors+ 0 author

The aim of this study was to show the clinical outcomes of the immediate loading of implants inserted by guided surgery in edentulous mandible patients. Edentulous mandible patients were diagnosed with oral examination, cone beam computerized tomogra...

(This article belongs to the Special Issue Digital Dentistry, Implantology and Maxillo-Facial Diseases)
  • Article
  • Open Access
39 Citations
8,050 Views
20 Pages

Background: Guided implant surgery appears to have several benefits, such as the possibility of inserting flapless implants in a prosthetically driven manner, avoiding dangerous anatomical structures. However, to date, only a few surgeons routinely u...

(This article belongs to the Special Issue Digital Dentistry: The Evolution of Dental Care)
  • Review
  • Open Access
7 Citations
3,031 Views
14 Pages

Comparative Analysis of Fully Guided and Free-Hand Orthognathic Surgery: Advancements, Precision, and Clinical Outcomes

  • Sophia Tsokkou,
  • Ioannis Konstantinidis,
  • Antonios Keramas,
  • Georgios Kiosis and ,
  • Kanellos Skourtsidis,
  • Danai Alexiou,
  • Georgia-Nektaria Keskesiadou,
  • Sofia Karachrysafi,
  • Theodora Papamitsou and
  • Ioannis Chatzistefanou
  • + 5 authors+ 0 author

11 June 2025

Background/Objectives: Orthognathic surgery has evolved with digital advancements, improving precision and predictability. Traditional free-hand techniques rely on surgeon expertise, often leading to variable outcomes. Fully guided approaches integra...

(This article belongs to the Special Issue Dentistry in the 21st Century: Challenges and Opportunities)
  • Article
  • Open Access
14 Citations
3,231 Views
11 Pages

Sodium Fluorescein-Guided Surgery for Resection of Brain Metastases from Lung Cancer: A Consecutive Case Series Study and Literature Review

  • Xing Cheng,
  • Jie Chen,
  • Ronghua Tang,
  • Jian Ruan and ,
  • Deqiang Mao and
  • Haifeng Yang
  • + 1 author+ 0 author

31 January 2023

(1) Introduction and objective: Surgical resection plays an important role in the multidisciplinary treatment of lung cancer patients with brain metastases (BMs). Precisely distinguishing the tumor border intraoperatively to improve and maximize the...

(This article belongs to the Special Issue Diagnosis and Treatment of Brain Metastases)
  • Article
  • Open Access
962 Views
13 Pages

Evaluation of the Precision and Accuracy of Computer-Guided Implant Surgery: A Prospective Clinical Study Comparing .STL Files from the Intraoral Rehabilitation Scanning with the Digital Project

  • Francesca Argenta,
  • Antonino Palazzolo,
  • Eugenio Romeo,
  • Saturnino Marco Lupi and ,
  • Tommaso Risciotti,
  • Massimo Scanferla and
  • Stefano Storelli
  • + 2 authors+ 0 author

6 February 2026

Objectives: This prospective cohort study aimed to evaluate the accuracy and precision of static computer-guided, flapless implant surgery in partially edentulous patients, comparing the virtually planned and clinically achieved implant positions. Ma...

(This article belongs to the Special Issue Recent Development and Emerging Trends in Dental Implants)
  • Article
  • Open Access
11 Citations
4,943 Views
17 Pages

Virtual Guided and Customized Orthognathic Surgery in Patients with Obstructive Sleep Apnea Syndrome: Accuracy and Clinical Outcomes

  • Marta Benito Anguita,
  • Saad Khayat,
  • Soledad López Martín,
  • Natalia Bravo Quelle and ,
  • Ignacio Navarro Cuéllar,
  • Ana López López,
  • José Luis Cebrián Carretero,
  • José Luis del Castillo Pardo de Vera,
  • Pablo Montes Fernández-Micheltorena and
  • Carlos Navarro Cuéllar
  • + 9 authors+ 4 authors

28 May 2025

Background: This preliminary case series aimed to evaluate the clinical and morphometric outcomes of maxillomandibular advancement (MMA) surgery in patients with severe obstructive sleep apnea (OSA) using virtual surgical planning (VSP), patient-spec...

(This article belongs to the Special Issue Innovations in Maxillofacial Surgery)
  • Review
  • Open Access
17 Citations
5,661 Views
15 Pages

20 December 2022

Background: This article provides a scoping review on the current status of Image-Guided Navigation with various forms of digital technologies, including Extended Reality, Augmented Reality Head-Mounted Displays (AR–HMDs) and Robot-Assisted Sur...

(This article belongs to the Section Intelligent Robots and Mechatronics)
  • Article
  • Open Access
23 Citations
5,751 Views
13 Pages

SEM-EDX Analysis of Metal Particles Deposition from Surgical Burs after Implant Guided Surgery Procedures

  • Giovanni Falisi,
  • Giordano Foffo,
  • Marco Severino,
  • Carlo Di Paolo and ,
  • Serena Bianchi,
  • Sara Bernardi,
  • Davide Pietropaoli,
  • Sofia Rastelli,
  • Roberto Gatto and
  • Gianluca Botticelli
  • + 5 authors+ 0 author

12 February 2022

The preparation of the implant site in guided surgery procedure takes place without irrigation, which could lead to increased friction of the drills with the formation and release of debris or metal particles. The presence of metal particles in the p...

(This article belongs to the Collection Advanced Surface Coating of Nanoparticles)

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