Special Issue "Advances in the Diagnosis and Treatment of Thyroid Carcinoma"
Deadline for manuscript submissions: 31 December 2021.
Interests: endocrine surgery, thyroid, parathyroid, mini-invasive surgery
In the last 40 years, the incidence of thyroid carcinoma has considerably increased, making it the most common endocrine malignancy. Even if, in most cases, the initial treatment is curative, a certain number of patients experience a poor course of the disease, with local or distant recurrence, and require further medical or surgical treatment, which considerably worsens their quality of life.
Indeed, thyroid cancer represents a heterogeneous disease, comprising different molecular and histological subtypes with distinct clinical behavior and prognosis.
In the last two decades, a great effort has been made to improve its diagnosis and surgical outcomes. Molecular biomarkers have been studied and introduced in clinical practice, and new pathological and clinical classifications have been proposed to take into account tumor behavior and risk of disease recurrence. At the same time, new devices and surgical approaches have been developed to improve radicality and reduce surgical trauma, including mini-invasive and remote access surgery, intraoperative monitoring of recurrent laryngeal nerve, and use of indocyanine green fluorescence to identify parathyroid glands.
Nevertheless, many issues remain a matter of debate, regarding, for example, the indication and extent of lymphectomy of the central compartment, the treatment of microcarcinoma, the therapeutic options for poorly differentiated and anaplastic carcinomas, and the indications and strategies in cases of recurrent disease.
This Special Issue of Cancers aims to present the latest research on the diagnosis and therapy of thyroid cancer.
Relevant topics include, but are not limited to:
- Thyroid cancer proteomics and metabolomics
- Advances in cytopathology and role of molecular markers in preoperative evaluation of thyroid nodules
- Treatment of microcarcinoma: surgical approach vs active surveillance
- Medullary thyroid carcinoma
- Intraoperative Nerve Monitoring (IONM) and experience with two-stage thyroidectomy
- Adequacy of lobo-isthmectomy in low and intermediate risk thyroid carcinoma
- Indications to prophylactic central compartment lymph node dissection
- Usefulness of indocyanine green fluorescence in preventing hypoparathyroidism
- The influence of lymph node metastasis on prognosis
- Predictive factors of structural recurrent disease
- Treatment of poorly differentiated and anaplastic thyroid carcinoma
- Therapeutic options for radioiodine-resistant thyroid cancer
- Indications and treatment of recurrent disease
- Remote access thyroidectomy
Dr. Fabio Medas
Dr. Pier Francesco Alesina
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- thyroid carcinoma, molecular markers, lymph node metastasis, prophylactic central compartment lymph node dissection, radical neck dissection, intraoperative nerve monitoring, recurrent disease, mini-invasive thyroidectomy