245 Results Found

Matrix metalloproteinases (MMPs), which are proteolytic enzymes, promote blood–brain barrier (BBB) disruption, leading to neuronal damage and neuroinflammation. Among them, MMP-9 upregulation serves as an inflammatory biomarker in the central n...

Abundant industrial experiences have shown that directional air drilling technology is effective for gas drainage when drilling broken and soft coal seams. In this paper, the Eulerian–Eulerian model was used to simulate the gas–solid two-...

In recent years, the unmanned aerial vehicle-assisted internet of vehicles has been extensively studied to enhance communication and computation services in vehicular environments where ground infrastructures are limited or absent. However, due to th...

The paper suggests a randomized model for dynamic migratory interaction of regional systems. The locally stationary states of migration flows in the basic and immigration systems are described by corresponding entropy operators. A soft randomization...

With network function virtualization (NFV) expanding from network center to edge, the service function chain (SFC) will gradually approach users to provide lower delay and higher-quality services. User mobility seriously affects the quality of servic...

Electron coherence is a fundamental quantum phenomenon in today’s ultrafast physics and chemistry research. Based on attosecond pump–probe schemes, ultrafast X-ray photoelectron imaging of molecules was used to monitor the coherent electr...

Cancer metastasis is the main cause of death in cancer patients; however, there is currently no effective method to predict and prevent metastasis of gastric cancer. Therefore, gaining an understanding of the molecular mechanism of tumor metastasis i...

While Tunisia endorsed the non-binding Global Compact for Migration (GCM), it has not yet ratified the binding International Convention on the Protection of the Rights of All Migrant Workers and Members of Their Families (ICRMW). In view of the overl...

Metastasis of cancer is the cause of the majority of cancer deaths. Active compound flaccidoxide-13-acetate, isolated from the soft coral Cladiella kashmani, has been found to exhibit anti-tumor activity. In this study, Boyden chamber analysis, Weste...

To address the issues of low model fitting accuracy and insufficient prediction capability caused by the multi-stage characteristics and batch-to-batch data distribution heterogeneity in the fermentation process of Pichia pastoris, this study propose...

A closely spaced set of high-resolution Chirp-Sonar and Sparker profiles and swath bathymetric data was acquired in 2013 for the I-AMICA Project off the Volturno River mouth (Southern Tyrrhenian Sea) by the Istituto per l’Ambiente Marino Costie...

In the current natural environment, due to the complexity of the background and the high similarity of the color between immature green tomatoes and the plant, the occlusion of the key organs (flower and fruit) by the leaves and stems will lead to lo...

Understanding cell migration is a key step in unraveling many physiological phenomena and predicting several pathologies, such as cancer metastasis. In particular, confinement has been proven to be a key factor in the cellular migration strategy choi...

The cable-driven soft arm is mostly made of soft material; it is difficult to control because of the material characteristics, so the traditional robot arm modeling and control methods cannot be directly applied to the soft robot arm. In this paper,...

On 11 March 2020, the World Health Organization declared COVID-19 to be a pandemic to be confronted by humanity. As a result, social isolation has become the norm in most countries, with the consequent replacement of face-to-face classes by classes m...

Solid-film electrets and cellular electrets are defined as promising insulating dielectric materials containing permanent electrostatic and polarizations. High-performance charging methods are critical for electret transducers. Unlike dielectric barr...

Background/Objectives: Soft tissue sarcomas are rare, heterogeneous tumors with limited therapeutic options and suboptimal outcomes in advanced stages. Lurbinectedin is a promising new antineoplastic alkylating agent. This study investigates its cyto...

The characteristics of the pore structure and gas migration in soft coalbeds are the premise of evaluating gas discharge in soft coalbeds. To explore the pore structure characteristics of soft coal masses, the No. 5 soft coalbed in the eastern zone o...

Commercially pure titanium and titanium alloys have been extensively used in materials to reconstruct the facial skeleton in different forms and sizes. There is yet to be a consensus on removing (or not) the plates and screws after osteosynthesis. Ou...

Background and Objectives: Soft-tissue healing, particularly rapid epithelialization, is a critical determinant of successful periodontal regenerative therapy. Fibroblast growth factor-2 (FGF-2) and enamel matrix derivative (EMD) are regenerative bio...

Soft tissue engineering has been seeking ways to mimic the natural extracellular microenvironment that allows cells to migrate and proliferate to regenerate new tissue. Therefore, the reconstruction of soft tissue requires a scaffold possessing the e...

Beverage cans are used for energy drinks, soft-drinks, sparkling waters, and beer. Bisphenol A is still part of the formulation of epoxy coatings of beverage cans. Due to concerns that bisphenol A acts as an endocrine-active substance, the migration...

Shoulder disorders are very common in clinical practice. Among several other pathologies, calcific tendinopathy of the rotator cuff tendons is frequently observed during the ultrasound examination of patients with painful shoulder. The deposition of...

Herein, a micro-patterned cell adhesive surface is prepared for the future design of medical devices. One-dimensional polydimethylsiloxane (PDMS) micro patterns were prepared by a photolithography process. We investigated the effect of microscale top...

The aim of this study was to evaluate the microscopic structure of soft tissue covering titanium plates and screws used in jaw surgery (mandible fracture and orthognathic surgery), after a minimum period of 12 months from insertion, and to quantify t...

Improving soft tissue attachment to implant abutments is a crucial factor for enduring health and maintenance of soft peri-implant tissue health. In this in vitro study we aimed to compare the biocompatibility of three different abutment surfaces: ti...

Helicobacter pylori is a motile bacterial pathogen that causes severe gastric diseases. H. pylori motility and chemotaxis are key colonization factors. Motility and chemotaxis are studied in many microbes, including H. pylori, using soft agar assays....

Cancer metastasis is one of the major causes of death in cancer. An active compound, 11-epi-sinulariolide acetate (11-epi-SA), isolated from the cultured soft coral Sinularia flexibilis has been examined for potential anti-cell migration and invasio...

Whole exome sequencing of invasive mammary carcinomas revealed the association of mutations in PTEN and ZFHX3 tumor suppressor genes (TSGs). We generated single and combined PTEN and ZFHX3 knock-outs (KOs) in the immortalized mammary epithelial cell...

Cell–matrix adhesion and cell migration are physiologically important processes that also play a major role in cancer spreading. In cultured cells, matrix adhesion depends on integrin-containing contacts such as focal adhesions. Flotillin-1 and floti...

A chondrosarcoma is a common tumor of the soft tissue and bone that has a high propensity to metastasize to distant organs. Nerve growth factor (NGF) is capable of promoting the progression and metastasis of several different types of tumors although...

Conventional plasma electrolytic oxidation treatments produce oxide coatings with micron-scale discharge pores, resulting in insulation and wear and corrosion resistance far below that expected of highly dense Al₂O₃ coatings. The introduction of cath...

Tissue regeneration relies on the mechanical properties of the surrounding environment, and it has already been shown that mechanostimulation is highly dependent on the stiffness of the native biological tissue. The main advantage of injectable hydro...

The extracellular matrix (ECM) regulates cellular function through the dynamic biomechanical and biochemical interplay between the resident cells and their microenvironment. Pathologically stiff ECM promotes phenotype changes in hepatocytes during li...

(1) Background: To assess orthodontic forced eruption (OFE) as a pre-restorative procedure for non-restorable permanent teeth with subgingival dental hard tissue defects after dental trauma. (2) Methods: A systematic electronic search of three databa...

In this paper, we investigate the Adaptive Service Migration (ASM) problem in dynamic satellite edge computing networks, focusing on Low Earth Orbit satellites with time-varying inter-satellite links. We formulate the ASM problem as a constrained opt...

Due to the rarity and heterogeneity of bone and soft-tissue sarcomas, investigation into molecular targets and new treatments has been particularly challenging. Although intensive chemotherapy and establishment of surgical procedures have improved th...

Four new cembranoids, sarcophelegans A–D (1–4) and six known analogues (5–10) were isolated from the South China Sea soft coral Sarcophyton elegans. Their structures were elucidated through detailed spectroscopic analysis, and the absolute configurati...

The mechanical micro-environment of cells and tissues influences key aspects of cell structure and function, including cell motility. For proper tissue development, cells need to migrate, interact, and form contacts. Cells are known to exert contract...

Soft magnetic materials are critical for efficient electromagnetic energy conversion, with their development evolving from traditional alloys like ferrites to amorphous/nanocrystalline materials and advanced multi-component alloys. While multi-compon...

Bladder cancer (BC) is a highly recurrent and invasive malignancy, with Mycobacterium bovis BCG serving as the primary immunotherapy, particularly for non-muscle-invasive bladder cancer (NMIBC). However, the mechanisms underlying BCG’s antitumo...

Nowadays, several real-world decision-making problems concerning falling economies, power crises, depleting resources, etc., require efficient decision-making. To solve such problems, researchers proposed several hybrid models by combining the spheri...

This study explores the dynamic field of 3D-printed hydrogels, emphasizing advancements and challenges in customization, fabrication, and functionalization for applications in biomedical engineering, soft robotics, and tissue engineering. It delves i...

The mechanisms by which the nuclear lamina of tumor cells influences tumor growth and migration are highly disputed. Lamin A and its variant lamin C are key lamina proteins that control nucleus stiffness and chromatin conformation. Downregulation of...

Traditional medical soft matrix used in a surgical treatment or in wound management was not good enough in both the structural support and interconnectivity to be applied in tissue engineering as a scaffold. Avian skeleton and feather rachises might...

Background/Objectives: Ewing sarcoma is an aggressive pediatric sarcoma of bone and soft tissues, with metastatic disease being the most significant prognostic factor of poor outcome. We have previously reported that WNT974, a selective Porcn inhibit...

Sinulariolide is an active compound isolated from the cultured soft coral Sinularia flexibilis. In this study, we investigate the migration and invasion effects of sinulariolide in hepatocellular carcinoma cell HA22T. Sinulariolide inhibited the mig...

Soft clay contamination is an increasingly global issue with significant implications for land development and human health. Electrokinetic remediation (EKR) has demonstrated significant potential for cleaning contaminated soils. It is crucial to dev...

Understanding how microscopic rearrangements manifest in macroscopic flow responses is one of the central goals of nonlinear rheological studies. Using the sequence-of-physical-processes framework, we present a natural 3D structure–rheology spa...

The use of extracellular matrix (ECM) biomaterials for soft tissue repair has proved extremely successful in animal models and in some clinical settings. The aim of the study was to investigate the effect of the commercially obtained CorMatrix biosca...