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Molecules 2015, 20(7), 13324-13335;

Bioactive Cembranoids from the South China Sea Soft Coral Sarcophyton elegans

School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China
East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China
Author to whom correspondence should be addressed.
Academic Editor: John Beutler
Received: 13 June 2015 / Accepted: 13 July 2015 / Published: 22 July 2015
(This article belongs to the Section Natural Products Chemistry)
Full-Text   |   PDF [1130 KB, uploaded 22 July 2015]   |  


Four new cembranoids, sarcophelegans A–D (14) and six known analogues (510) were isolated from the South China Sea soft coral Sarcophyton elegans. Their structures were elucidated through detailed spectroscopic analysis, and the absolute configuration of 1 was confirmed by single-crystal X-ray diffraction. The antimigratory potential of compounds 110 were evaluated and compounds 2 and 6 were found to inhibit human breast tumor MDA-MB-231 cell migration at 10 μM. View Full-Text
Keywords: Sarcophyton elegans; cembranoids; antimigratory activity Sarcophyton elegans; cembranoids; antimigratory activity

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Liu, X.; Zhang, J.; Liu, Q.; Tang, G.; Wang, H.; Fan, C.; Yin, S. Bioactive Cembranoids from the South China Sea Soft Coral Sarcophyton elegans. Molecules 2015, 20, 13324-13335.

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