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Bioactive Cembranoids from the South China Sea Soft Coral Sarcophyton elegans

1
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China
2
East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China
*
Author to whom correspondence should be addressed.
Academic Editor: John Beutler
Molecules 2015, 20(7), 13324-13335; https://doi.org/10.3390/molecules200713324
Received: 13 June 2015 / Accepted: 13 July 2015 / Published: 22 July 2015
(This article belongs to the Section Natural Products Chemistry)
Four new cembranoids, sarcophelegans A–D (14) and six known analogues (510) were isolated from the South China Sea soft coral Sarcophyton elegans. Their structures were elucidated through detailed spectroscopic analysis, and the absolute configuration of 1 was confirmed by single-crystal X-ray diffraction. The antimigratory potential of compounds 110 were evaluated and compounds 2 and 6 were found to inhibit human breast tumor MDA-MB-231 cell migration at 10 μM. View Full-Text
Keywords: Sarcophyton elegans; cembranoids; antimigratory activity Sarcophyton elegans; cembranoids; antimigratory activity
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MDPI and ACS Style

Liu, X.; Zhang, J.; Liu, Q.; Tang, G.; Wang, H.; Fan, C.; Yin, S. Bioactive Cembranoids from the South China Sea Soft Coral Sarcophyton elegans. Molecules 2015, 20, 13324-13335.

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