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384 Results Found

  • Article
  • Open Access
10 Citations
6,790 Views
14 Pages

20 March 2018

The use of expert knowledge to quantify a Bayesian Network (BN) is necessary when data is not available. This however raises questions regarding how opinions from multiple experts can be used in a BN. Linear pooling is a popular method for combining...

  • Brief Report
  • Open Access
6 Citations
2,713 Views
7 Pages

Implementation of Sample Pooling Procedure Using a Rapid SARS-CoV-2 Diagnostic Real-Time PCR Test Performed Prior to Hospital Admission of People with Intellectual Disabilities

  • Antonino Musumeci,
  • Mirella Vinci,
  • Francesca L’Episcopo,
  • Alda Ragalmuto,
  • Vincenzo Neri,
  • Michele Roccella,
  • Giuseppe Quatrosi,
  • Luigi Vetri and
  • Francesco Calì

Reliability, accuracy, and timeliness of diagnostic testing for SARS-CoV-2 infection have allowed adequate public health management of the disease, thus notably helping the timely mapping of viral spread within the community. Furthermore, the most vu...

  • Article
  • Open Access
127 Views
23 Pages

Shape-Constrained ResU-Net for Old Landslides Detection in the Loess Plateau

  • Lulu Peng,
  • Mingtao Ding,
  • Qiang Xue,
  • Ying Dong,
  • Yunlong Li,
  • Pengxiang Zhou and
  • Zhenhong Li

5 January 2026

The Loess Plateau is highly susceptible to landslides due to its fragile geological structure and frequent human activities, particularly old landslides with historical structural damage. The features of these landslides in remote sensing images beco...

  • Article
  • Open Access
3 Citations
2,807 Views
12 Pages

Accelerating the Laboratory Testing Capacity through Saliva Pooling Prior to Direct RT-qPCR for SARS-CoV-2 Detection

  • Maria Mardalena Martini Kaisar,
  • Sheila Jonnatan,
  • Tria Asri Widowati,
  • Helen Kristin,
  • Suraj Rajan Vasandani,
  • Caroline Mahendra and
  • Soegianto Ali

14 December 2022

The testing capacity of the laboratory is paramount for better control of the pandemic caused by SARS-CoV-2. The pooling method is promising to increase testing capacity, and the use of direct NAAT-based detection of SARS-CoV-2 on a non-invasive spec...

  • Feature Paper
  • Article
  • Open Access
684 Views
23 Pages

18 June 2025

The problem of combining statistical evidence concerning an unknown, contained in each of the k Bayesian inference bases, is discussed. This can be considered as being related to the problem of pooling k priors to determine a consensus prior, but the...

  • Article
  • Open Access
73 Citations
6,208 Views
19 Pages

Spatial Prior Fuzziness Pool-Based Interactive Classification of Hyperspectral Images

  • Muhammad Ahmad,
  • Asad Khan,
  • Adil Mehmood Khan,
  • Manuel Mazzara,
  • Salvatore Distefano,
  • Ahmed Sohaib and
  • Omar Nibouche

13 May 2019

Acquisition of labeled data for supervised Hyperspectral Image (HSI) classification is expensive in terms of both time and costs. Moreover, manual selection and labeling are often subjective and tend to induce redundancy into the classifier. Active l...

  • Systematic Review
  • Open Access
15 Citations
4,299 Views
10 Pages

Objectives: Hypersensitivity reactions (HSRs) are uncommon but serious adverse events following the administration of iodinated contrast media (ICM) prior to CT imaging. While premedication is almost universally given in high-risk patients, there is...

  • Article
  • Open Access
1 Citations
3,145 Views
12 Pages

Swimming Pool-Related Outbreak of a Rare gp60 Subtype of Cryptosporidium hominis, England, October 2016

  • Helen Bagnall,
  • Rachel M. Chalmers,
  • Michelle Henderson,
  • Stewart Sorrell,
  • Guy Robinson,
  • Kristin Elwin and
  • Gayle Dolan

9 November 2021

In October 2016, Public Health England was initially notified of four cases of cryptosporidiosis among users of two swimming pools. We investigated to identify further cases, the outbreak source, and ensure the implementation of appropriate control m...

  • Article
  • Open Access
6 Citations
5,012 Views
18 Pages

Pooling biological specimens prior to performing expensive laboratory assays has been shown to be a cost effective approach for estimating parameters of interest. In addition to requiring specialized statistical techniques, however, the pooling of s...

  • Article
  • Open Access
26 Citations
4,222 Views
12 Pages

8 March 2020

Refining microstructure is an important issue for laser additive manufacturing (LAM) of titanium alloy. In the present work, the microstructures of LAM-fabricated Ti6Al4V alloy were refined using a low energy density with the combination of a small s...

  • Article
  • Open Access
3 Citations
9,127 Views
19 Pages

This study extends the political science and political psychology literature on the political ideology of lawmakers by addressing the following question: How stable is a legislator’s political ideology over time? In doing so, we employ Nokken&n...

  • Article
  • Open Access
2 Citations
4,862 Views
17 Pages

27 August 2021

The transfer of water from a swimming pool to the treatment location is key in determining the effectiveness of water treatment by filtration in removing turbidity and managing the risk from particulate material, including microbial pathogens, such a...

  • Article
  • Open Access
1 Citations
2,392 Views
44 Pages

3 January 2024

Bayesian estimation of latent variable models provides some unique advantages to researchers working with small samples and complex models when compared with the more commonly used maximum likelihood approach. A key aspect of Bayesian modeling involv...

  • Systematic Review
  • Open Access
7 Citations
5,498 Views
16 Pages

Safety and Efficacy of Laser Interstitial Thermal Therapy as Upfront Therapy in Primary Glioblastoma and IDH-Mutant Astrocytoma: A Meta-Analysis

  • Aryan Pandey,
  • Anubhav Chandla,
  • Mahlet Mekonnen,
  • Gabrielle E. A. Hovis,
  • Zoe E. Teton,
  • Kunal S. Patel,
  • Richard G. Everson,
  • Madhuri Wadehra and
  • Isaac Yang

3 June 2024

Although primary studies have reported the safety and efficacy of LITT as a primary treatment in glioma, they are limited by sample sizes and institutional variation in stereotactic parameters such as temperature and laser power. The current literatu...

  • Article
  • Open Access
12 Citations
4,874 Views
28 Pages

Breast Cancer Tumor Classification Using a Bag of Deep Multi-Resolution Convolutional Features

  • David Clement,
  • Emmanuel Agu,
  • John Obayemi,
  • Steve Adeshina and
  • Wole Soboyejo

Breast cancer accounts for 30% of all female cancers. Accurately distinguishing dangerous malignant tumors from benign harmless ones is key to ensuring patients receive lifesaving treatments on time. However, as doctors currently do not identify 10%...

  • Systematic Review
  • Open Access
2 Citations
2,346 Views
16 Pages

An Exploration of the Viral Coverage of Mosquito Viromes Using Meta-Viromic Sequencing: A Systematic Review and Meta-Analysis

  • Shenglin Chen,
  • Yuan Fang,
  • Ryosuke Fujita,
  • Emad I. M. Khater,
  • Yuanyuan Li,
  • Wenya Wang,
  • Peijun Qian,
  • Lulu Huang,
  • Zhaoyu Guo and
  • Yi Zhang
  • + 1 author

The aim of this review was to delve into the extent of mosquito virome coverage (proportion of viral reads) via meta-viromic sequencing and uncover potential factors of heterogeneity that could impact this coverage. Data sources were PubMed, Web of S...

  • Article
  • Open Access
14 Citations
4,415 Views
13 Pages

Ambient Air Pollution and Respiratory Health in Sub-Saharan African Children: A Cross-Sectional Analysis

  • Yutong Samuel Cai,
  • Harry Gibson,
  • Rema Ramakrishnan,
  • Mohammad Mamouei and
  • Kazem Rahimi

Ambient air pollution is projected to become a major environmental risk in sub-Saharan Africa (SSA). Research into its health impacts is hindered by limited data. We aimed to investigate the cross-sectional relationship between particulate matter wit...

  • Article
  • Open Access
7 Citations
5,902 Views
22 Pages

This paper discusses Bayesian model averaging (BMA) in Stochastic Frontier Analysis and investigates inference sensitivity to prior assumptions made about the scale parameter of (in)efficiency. We turn our attention to the “standard” prio...

  • Article
  • Open Access
3 Citations
2,252 Views
19 Pages

20 February 2024

Previous studies have demonstrated that cold pools play a pivotal role in the initiation and organization of convection, yet their influence on the evolution of gust fronts (GFs) remains inadequately understood. A destructive wind event associated wi...

  • Systematic Review
  • Open Access
1,416 Views
22 Pages

The Impact of Statin Use on Sepsis Mortality: A Systematic Review and Meta-Analysis

  • Constantinos Philippou,
  • Constantinos Tsioutis,
  • Maria Tsiappari,
  • Nikolaos Spernovasilis,
  • Dimitrios Papadopoulos and
  • Aris P. Agouridis

30 August 2025

Background and Objectives: Statins are among the most prescribed medications globally, primarily due to their potent lipid-lowering capabilities. This systematic review aims to identify, synthesize and evaluate current evidence regarding the potentia...

  • Article
  • Open Access
28 Citations
6,472 Views
16 Pages

Evidence of Altered Glycosylation of Serum Proteins Prior to Pancreatic Cancer Diagnosis

  • Shibu Krishnan,
  • Harry J. Whitwell,
  • Joy Cuenco,
  • Aleksandra Gentry-Maharaj,
  • Usha Menon,
  • Stephen P. Pereira,
  • Marco Gaspari and
  • John F. Timms

9 December 2017

Biomarkers for the early detection of pancreatic cancer are urgently needed. The aim of this pilot study was to evaluate changes in serum N-glycoproteins and their glycosylation status prior to clinical presentation of pancreatic cancer that may be p...

  • Article
  • Open Access
4 Citations
6,384 Views
11 Pages

Using Undergraduate Researchers to Build Vector and West Nile Virus Surveillance Capacity

  • Grant Hokit,
  • Sam Alvey,
  • Jennifer M. O. Geiger,
  • Gregory D. Johnson,
  • Marni G. Rolston,
  • Daniel T. Kinsey and
  • Neva Tall Bear

Vector surveillance for infectious diseases is labor intensive and constantly threatened by budget decisions. We report on outcomes of an undergraduate research experience designed to build surveillance capacity for West Nile Virus (WNV) in Montana (...

  • Article
  • Open Access
2 Citations
3,737 Views
13 Pages

Pilot Investigation of Anti-Salmonella Antibodies in Oral Fluids from Salmonella Typhimurium Vaccinated and Unvaccinated Swine Herds

  • Alessia De Lucia,
  • Shaun A. Cawthraw,
  • Richard Piers Smith,
  • Rob Davies,
  • Carlo Bianco,
  • Fabio Ostanello and
  • Francesca Martelli

14 August 2021

Oral fluid (OF) can be a simple, cheap and non-invasive alternative to serum or meat juice for the diagnosis and surveillance of important pathogens in pigs. This study was conducted on four Salmonella Typhimurium-positive farrow-to-finish pig farms:...

  • Article
  • Open Access
16 Citations
3,504 Views
16 Pages

CNN-Based Illumination Estimation with Semantic Information

  • Ho-Hyoung Choi,
  • Hyun-Soo Kang and
  • Byoung-Ju Yun

13 July 2020

For more than a decade, both academia and industry have focused attention on the computer vision and in particular the computational color constancy (CVCC). The CVCC is used as a fundamental preprocessing task in a wide range of computer vision appli...

  • Systematic Review
  • Open Access
18 Citations
10,756 Views
15 Pages

Real-World Safety of COVID-19 mRNA Vaccines: A Systematic Review and Meta-Analysis

  • Wanqian Xu,
  • Weigang Ren,
  • Tongxin Wu,
  • Qin Wang,
  • Mi Luo,
  • Yongxiang Yi and
  • Junwei Li

19 June 2023

With the mass vaccination program for COVID-19 mRNA vaccines, there has been sufficient real-world study (RWS) on the topic to summarize their safety in the total population and in immunocompromised (IC) patients who were excluded from phase 3 clinic...

  • Systematic Review
  • Open Access
12 Citations
4,792 Views
12 Pages

A Meta-Analysis to Assess the Efficacy of HER2-Targeted Treatment Regimens in HER2-Positive Metastatic Colorectal Cancer (mCRC)

  • Akshit Chitkara,
  • Muhammad Bakhtiar,
  • Ibrahim Halil Sahin,
  • Dennis Hsu,
  • Janie Zhang,
  • FNU Anamika,
  • Mahnoor Mahnoor,
  • Rabeea Ahmed,
  • Sepideh Gholami and
  • Anwaar Saeed

7 September 2023

Recent trials provide evidence that HER2 is a potential new target for patients with colorectal cancer. While HER2-positive tumors do not show a very encouraging response to anti-HER2-positive agents like trastuzumab alone, promising results have bee...

  • Review
  • Open Access
42 Citations
7,099 Views
16 Pages

Introduction: Prior meta-analysis has reported mortality rates among post-operative bariatric patients, but they have not considered psychiatric factors like suicide contributing to mortality. Objectives: The current meta-analysis aims to determine t...

  • Systematic Review
  • Open Access
7 Citations
3,409 Views
11 Pages

20 December 2022

Contrary to traditional assumptions, recent evidence suggests that neoadjuvant systemic therapy (NST) given for invasive breast cancer may eradicate co-existent ductal carcinoma in-situ (DCIS), which may facilitate de-escalation of breast resections....

  • Review
  • Open Access
38 Citations
5,541 Views
17 Pages

18F-Facbc in Prostate Cancer: A Systematic Review and Meta-Analysis

  • Riccardo Laudicella,
  • Domenico Albano,
  • Pierpaolo Alongi,
  • Giovanni Argiroffi,
  • Matteo Bauckneht,
  • Sergio Baldari,
  • Francesco Bertagna,
  • Michele Boero,
  • Giuseppe De Vincentis and
  • Angelo Del Sole
  • + 8 authors

11 September 2019

Trans-1-amino-3-18F-fluorocyclobutanecarboxylic-acid (anti-[18F]-FACBC) has been approved for the detection of prostate cancer (PCa) in patients with elevated prostate-specific-antigen following prior treatment. This review and meta-analysis aimed to...

  • Article
  • Open Access
2,418 Views
11 Pages

18F-Fluoroazomycin Arabinoside (FAZA) PET/MR as a Biomarker of Hypoxia in Rectal Cancer: A Pilot Study

  • Ur Metser,
  • Andres Kohan,
  • Catherine O’Brien,
  • Rebecca K. S. Wong,
  • Claudia Ortega,
  • Patrick Veit-Haibach,
  • Brandon Driscoll,
  • Ivan Yeung and
  • Adam Farag

30 August 2024

Tumor hypoxia is a negative prognostic factor in many tumors and is predictive of metastatic spread and poor responsiveness to both chemotherapy and radiotherapy. Purpose: To assess the feasibility of using 18F-Fluoroazomycin arabinoside (FAZA) PET/M...

  • Systematic Review
  • Open Access
13 Citations
3,593 Views
10 Pages

Diagnostic Accuracy of Contrast-Enhanced Ultrasound (CEUS) in the Detection of Muscle-Invasive Bladder Cancer: A Systematic Review and Diagnostic Meta-Analysis

  • Antonio Tufano,
  • Davide Rosati,
  • Martina Moriconi,
  • Valerio Santarelli,
  • Vittorio Canale,
  • Stefano Salciccia,
  • Alessandro Sciarra,
  • Giorgio Franco,
  • Vito Cantisani and
  • Giovanni Battista Di Pierro

1 February 2024

Background: Contrast-enhanced ultrasound (CEUS) is a diagnostic tool that is gaining popularity for its ability to improve overall diagnostic accuracy in bladder cancer (BC) staging. Our aim is to determine the cumulative diagnostic performance of CE...

  • Article
  • Open Access
9 Citations
5,413 Views
13 Pages

As the direction and strategies of new ventures depend on the top management team (TMT)’s stability and continuous efforts, we investigate the relationship between executive turnover and research and development (R&D) investment investment....

  • Article
  • Open Access
9 Citations
3,272 Views
16 Pages

27 July 2022

In this paper, we present FVR-Net, which is a novel finger vein recognition network using a convolutional neural network (CNN) with a hybrid pooling mechanism. The scheme is based on the use of a block-wise feature extraction network to extract discr...

  • Article
  • Open Access
2,591 Views
18 Pages

Genetic Divergence and Connectivity among Gene Pools of Polyprion americanus

  • Pablo Presa,
  • Alfonso Pita,
  • Nédia R. Matusse and
  • Montse Pérez

15 January 2023

Three regional gene pools of Polyprion americanus have been described so far, i.e., the North Atlantic, the Southwest Atlantic, and the Indo-Pacific Ocean. However, there is taxonomic uncertainty about the Southeast Atlantic population and there is s...

  • Article
  • Open Access
9 Citations
2,618 Views
26 Pages

A Physically Motivated Heat Source Model for Laser Beam Welding

  • Philipp Hartwig,
  • Nasim Bakir,
  • Lisa Scheunemann,
  • Andrey Gumenyuk,
  • Jörg Schröder and
  • Michael Rethmeier

6 April 2024

In this contribution, we present a physically motivated heat source model for the numerical modeling of laser beam welding processes. Since the calibration of existing heat source models, such as the conic or Goldak model, is difficult, the represent...

  • Article
  • Open Access
5 Citations
2,948 Views
9 Pages

Using Genomics to Measure Phenomics: Repeatability of Bull Prolificacy in Multiple-Bull Pastures

  • Gary L. Bennett,
  • John W. Keele,
  • Larry A. Kuehn,
  • Warren M. Snelling,
  • Aaron M. Dickey,
  • Darrell Light,
  • Robert A. Cushman and
  • Tara G. McDaneld

Phenotypes are necessary for genomic evaluations and management. Sometimes genomics can be used to measure phenotypes when other methods are difficult or expensive. Prolificacy of bulls used in multiple-bull pastures for commercial beef production is...

  • Systematic Review
  • Open Access
210 Views
23 Pages

8 January 2026

Background: Solid organ transplant recipients (SOTRs) are highly vulnerable to severe COVID-19 infection, yet initial vaccine trials provided limited data on efficacy and safety in this immunocompromised population. Heterogeneous seroconversion rates...

  • Article
  • Open Access
13 Citations
8,188 Views
15 Pages

22 October 2012

Temperate conifer forests in the Colorado Front Range are fire-adapted ecosystems where wildland fires leave a legacy in the form of char and charcoal. Long-term soil charcoal C (CC) pools result from the combined effects of wildland fires, abovegrou...

  • Article
  • Open Access
1 Citations
3,915 Views
20 Pages

21 July 2021

Vertical distributions of biogenic silica (bSi), particulate inorganic carbon (PIC) and key biomineral-forming phytoplankton indicate vertical zoning, or partitioning, during the late summer stratified period in the northeast Atlantic. Coccolithophor...

  • Review
  • Open Access
1 Citations
2,172 Views
14 Pages

Does Prior Respiratory Viral Infection Provide Cross-Protection Against Subsequent Respiratory Viral Infections? A Systematic Review and Meta-Analysis

  • Vennila Gopal,
  • Matthew Chung Yi Koh,
  • Jinghao Nicholas Ngiam,
  • Ong Hang-Cheng,
  • Jyoti Somani,
  • Paul Anatharajah Tambyah and
  • Jeremy Tey

19 June 2024

The epidemiology of different respiratory viral infections is believed to be affected by prior viral infections in addition to seasonal effects. This PROSPERO-registered systematic review identified 7388 studies, of which six met our criteria to answ...

  • Article
  • Open Access
2 Citations
1,331 Views
13 Pages

Quantifying Uncertainty of Insurance Claims Based on Expert Judgments

  • Budhi Handoko,
  • Yeny Krista Franty and
  • Fajar Indrayatna

13 January 2025

In Bayesian statistics, prior specification has an important role in determining the quality of posterior estimates. We use expert judgments to quantify uncertain quantities and produce appropriate prior distribution. The aim of this study was to qua...

  • Communication
  • Open Access
6 Citations
3,518 Views
7 Pages

RT-dPCR in Mosquito Samples for ZIKV Detection: Effects of RNA Extraction and Reverse Transcription in Target Concentration

  • Paula Rodrigues de Almeida,
  • Ana Karolina Antunes Eisen,
  • Meriane Demoliner and
  • Fernando Rosado Spilki

30 July 2020

Zika virus (ZIKV) is an important arbovirus, responsible for recent outbreaks of Guillain Barré Syndrome and Congenital Zika Syndrome (CZS). After thousands of CZS cases, ZIKV is under constant surveillance in Brazil. Reliable and robust detec...

  • Article
  • Open Access
13 Citations
4,455 Views
12 Pages

Diagnostic Procedures to Detect Xylella fastidiosa in Nursery Stocks and Consignments of Plants for Planting

  • Giuliana Loconsole,
  • Stefania Zicca,
  • Lorenzo Manco,
  • Oumaima El Hatib,
  • Giuseppe Altamura,
  • Oriana Potere,
  • Vito Elicio,
  • Franco Valentini,
  • Donato Boscia and
  • Maria Saponari

26 September 2021

Preventive measures for infectious diseases caused by the harmful plant pathogenic bacterium Xylella fastidiosa include inspections and diagnostic tests on imported consignments of plants and in nurseries. Currently, mandatory checks on plant propaga...

  • Article
  • Open Access
3,186 Views
14 Pages

Microparticles as Viral RNA Carriers from Stool for Stable and Sensitive Surveillance

  • Emmanuel George Kifaro,
  • Mi Jung Kim,
  • Seungwon Jung,
  • Yoon-ha Jang,
  • Sungyeon Moon,
  • Dong-Hun Lee,
  • Chang-Seon Song,
  • Gerald Misinzo and
  • Sang Kyung Kim

Since its discovery, polymerase chain reaction (PCR) has emerged as an important technology for the diagnosis and identification of infectious diseases. It is a highly sensitive and reliable nucleic acids (NA) detection tool for various sample types....

  • Review
  • Open Access
23 Citations
4,571 Views
19 Pages

18 January 2022

(1) Background: The objective of this review was to synthesize available data on the use of machine learning to evaluate its accuracy (as determined by pooled sensitivity and specificity) in detecting keratoconus (KC), and measure reporting completen...

  • Article
  • Open Access
3 Citations
2,770 Views
13 Pages

Hypermetabolic Ipsilateral Supraclavicular and Axillary Lymphadenopathy: Optimal Time Point for Performing an 18F-FDG PET/CT after COVID-19 Vaccination

  • Kwadwo Antwi,
  • Federico Caobelli,
  • Ken Kudura,
  • Hans-Georg Buchholz,
  • Martin Hoffmann and
  • Mathias Schreckenberger

6 December 2022

Background: We aimed to evaluate the incidence of severe acute respiratory syndrome coronavirus type-2 (SARS-CoV2) vaccine-related hypermetabolic lymphadenopathy (HLA) and evaluate which time point produces the least number of false-positive findings...

  • Review
  • Open Access
2 Citations
992 Views
15 Pages

16 June 2025

Background: Advanced adrenocortical carcinoma (ACC) remains a challenging malignancy with limited therapeutic options. Multi-kinase inhibitors (MKIs), either alone or in combination with immuno-oncology (IO) agents, have been investigated in recent s...

  • Article
  • Open Access
452 Views
18 Pages

11 December 2025

Accurate and real-time detection of polyps in colonoscopy is a critical task for the early prevention of colorectal cancer. The primary difficulties include insufficient extraction of multi-scale contextual cues for polyps of different sizes, ineffic...

  • Article
  • Open Access
23 Citations
3,434 Views
17 Pages

Long-Term Advantages of Ovarian Reserve Maintenance and Follicle Development Using Adipose Tissue-Derived Stem Cells in Ovarian Tissue Transplantation

  • Luciana Cacciottola,
  • Thu Y. T. Nguyen,
  • Maria C. Chiti,
  • Alessandra Camboni,
  • Christiani A. Amorim,
  • Jacques Donnez and
  • Marie-Madeleine Dolmans

15 September 2020

(1) Background: Ovarian tissue transplantation with adipose tissue-derived stem cells (ASCs) has been shown to enhance graft vascularization and increase follicle survival after a short interval of 7 days. The aim of the present study was to investig...

  • Systematic Review
  • Open Access
4 Citations
3,154 Views
13 Pages

18 September 2024

Prior to the introduction of COVID-19 vaccines, patients with severe mental illness (SMI) were at greater risk of COVID-19-related outcomes than the general population. It is not yet clear whether COVID-19 vaccines have reduced the risk gap. We syste...

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