- Review
Mitochondriopathies as a Clue to Systemic Disorders—Analytical Tools and Mitigating Measures in Context of Predictive, Preventive, and Personalized (3P) Medicine
- Alena Liskova,
- Marek Samec,
- Lenka Koklesova,
- Erik Kudela,
- Peter Kubatka and
- Olga Golubnitschaja
The mitochondrial respiratory chain is the main site of reactive oxygen species (ROS) production in the cell. Although mitochondria possess a powerful antioxidant system, an excess of ROS cannot be completely neutralized and cumulative oxidative dama...