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584 Results Found

  • Article
  • Open Access
18 Citations
5,952 Views
21 Pages

Mathematical Analysis and Numerical Solution of a Model of HIV with a Discrete Time Delay

  • Abraham J. Arenas,
  • Gilberto González-Parra,
  • Jhon J. Naranjo,
  • Myladis Cogollo and
  • Nicolás De La Espriella

28 January 2021

We propose a mathematical model based on a set of delay differential equations that describe intracellular HIV infection. The model includes three different subpopulations of cells and the HIV virus. The mathematical model is formulated in such a way...

  • Article
  • Open Access
2,486 Views
25 Pages

In this article, we propose a nonlinear mathematical model that incorporates a discrete time delay. The model is used to analyze the dynamics of a socioeconomic system that includes economic growth, corruption, and unemployment. We introduce the time...

  • Article
  • Open Access
12 Citations
3,528 Views
20 Pages

Mathematical Modeling of Toxoplasmosis Considering a Time Delay in the Infectivity of Oocysts

  • Gilberto González-Parra,
  • Sharmin Sultana and
  • Abraham J. Arenas

24 January 2022

In this paper, we study the effect of the introduction of a time delay on the dynamics of toxoplasmosis. This time delay is the elapsed time from when oocysts become present in the environment and when they become infectious. We construct a mathemati...

  • Article
  • Open Access
1 Citations
2,061 Views
20 Pages

10 August 2023

In this paper, we construct a more realistic mathematical model to study toxoplasmosis dynamics. The model considers two discrete time delays. The first delay is related to the latent phase, which is the time lag between when a susceptible cat has ef...

  • Article
  • Open Access
26 Citations
4,045 Views
30 Pages

Mathematical Modeling of COVID-19 Dynamics under Two Vaccination Doses and Delay Effects

  • Gabriel Sepulveda,
  • Abraham J. Arenas and
  • Gilberto González-Parra

10 January 2023

The aim of this paper is to investigate the qualitative behavior of the COVID-19 pandemic under an initial vaccination program. We constructed a mathematical model based on a nonlinear system of delayed differential equations. The time delay represen...

  • Article
  • Open Access
16 Citations
5,476 Views
23 Pages

The first round of vaccination against coronavirus disease 2019 (COVID-19) began in early December of 2020 in a few countries. There are several vaccines, and each has a different efficacy and mechanism of action. Several countries, for example, the...

  • Article
  • Open Access
6 Citations
4,758 Views
19 Pages

Mathematical Model Describing HIV Infection with Time-Delayed CD4 T-Cell Activation

  • Hernán Darío Toro-Zapata,
  • Carlos Andrés Trujillo-Salazar and
  • Edwin Mauricio Carranza-Mayorga

4 July 2020

A mathematical model composed of two non-linear differential equations that describe the population dynamics of CD4 T-cells in the human immune system, as well as viral HIV viral load, is proposed. The invariance region is determined, classical equil...

  • Feature Paper
  • Article
  • Open Access
1,350 Views
23 Pages

Qualitative Analysis of a COVID-19 Mathematical Model with a Discrete Time Delay

  • Abraham J. Arenas,
  • Gilberto González-Parra and
  • Miguel Saenz Saenz

31 December 2024

The aim of this paper is to investigate the qualitative behavior of a mathematical model of the COVID-19 pandemic. The constructed SAIRS-type mathematical model is based on nonlinear delay differential equations. The discrete-time delay is introduced...

  • Article
  • Open Access
6 Citations
1,989 Views
16 Pages

A Novel Hybrid Crossover Dynamics of Monkeypox Disease Mathematical Model with Time Delay: Numerical Treatments

  • Nasser H. Sweilam,
  • Seham M. Al-Mekhlafi,
  • Saleh M. Hassan,
  • Nehaya R. Alsenaideh and
  • Abdelaziz E. Radwan

In this paper, we improved a mathematical model of monkeypox disease with a time delay to a crossover model by incorporating variable-order and fractional differential equations, along with stochastic fractional derivatives, in three different time i...

  • Article
  • Open Access
1,794 Views
13 Pages

1 June 2023

In this paper, a mathematical model based on the T-S fuzzy model is proposed to solve the fault estimation (FE) and fault-tolerant control (FTC) problem for singular nonlinear time-varying delay (TVD) systems with sensor fault. TVD is is extremely di...

  • Article
  • Open Access
4 Citations
3,169 Views
15 Pages

1 February 2024

Hepatitis B is a liver disease caused by the human hepatitis B virus (HBV). Mathematical models help further the understanding of the processes involved and help make predictions. The basic reproduction number, R0, is an index that predicts whether t...

  • Article
  • Open Access
8 Citations
7,581 Views
17 Pages

Mathematical Modeling of Bacteria Communication in Continuous Cultures

  • Maria Vittoria Barbarossa and
  • Christina Kuttler

16 May 2016

Quorum sensing is a bacterial cell-to-cell communication mechanism and is based on gene regulatory networks, which control and regulate the production of signaling molecules in the environment. In the past years, mathematical modeling of quorum sensi...

  • Article
  • Open Access
10 Citations
3,003 Views
21 Pages

Stability Analysis of Delayed COVID-19 Models

  • Mohamed A. Zaitri,
  • Cristiana J. Silva and
  • Delfim F. M. Torres

13 August 2022

We analyze mathematical models for COVID-19 with discrete time delays and vaccination. Sufficient conditions for the local stability of the endemic and disease-free equilibrium points are proved for any positive time delay. The stability results are...

  • Article
  • Open Access
11 Citations
3,508 Views
28 Pages

The EOQ Model for Deteriorating Items with a Conditional Trade Credit Linked to Order Quantity in a Supply Chain System

  • Kun-Jen Chung,
  • Jui-Jung Liao,
  • Hari Mohan Srivastava,
  • Shih-Fang Lee and
  • Shy-Der Lin

18 September 2021

For generality, we observed that some of the optimization methods lack the mathematical rigor and some of them are based on intuitive arguments which result in the solution procedures being questionable from logical viewpoints of a mathematical analy...

  • Article
  • Open Access
1,791 Views
36 Pages

10 October 2024

This study investigates a symmetric fractional-order epidemic model with time delays and non-monotonic incidence rates, considering two viral strains. By confirming the existence, uniqueness, and boundedness of the system’s solutions, the resea...

  • Article
  • Open Access
2,414 Views
28 Pages

On a Model of Rumors Spreading Through Social Media

  • Laurance Fakih,
  • Andrei Halanay and
  • Florin Avram

26 August 2025

Rumors have become a serious issue in today’s modern era, particularly in view of increased activity in social and online platforms. False information can go viral almost instantaneously through social networks, which immediately affect society...

  • Article
  • Open Access
883 Views
28 Pages

27 May 2025

This paper is devoted to the study of the dynamical behaviors of a socioeconomic mathematical model with a discrete time delay. The model includes economic growth, corruption, and unemployment, which are some of the main factors driving the economy o...

  • Article
  • Open Access
1 Citations
2,416 Views
17 Pages

Stability Analysis in a Mathematical Model for Allergic Reactions

  • Rawan Abdullah,
  • Irina Badralexi and
  • Andrei Halanay

31 January 2024

We present a mathematical model that captures the dynamics of the immune system during allergic reactions. Using delay differential equations, we depict the evolution of T cells, APCs, and IL6, considering cell migration between various body compartm...

  • Article
  • Open Access
22 Citations
3,815 Views
20 Pages

The Inventory Model for Deteriorating Items under Conditions Involving Cash Discount and Trade Credit

  • Kun-Jen Chung,
  • Jui-Jung Liao,
  • Shy-Der Lin,
  • Sheng-Tu Chuang and
  • Hari Mohan Srivastava

In the year 2004, Chang and Teng investigated an inventory model for deteriorating items in which the supplier not only provides a cash discount, but also allows a permissible delay in payments. The main purpose of the present investigation is three-...

  • Article
  • Open Access
2 Citations
1,787 Views
36 Pages

10 July 2024

This mathematical model delves into the dynamics of the immune system during Chronic Myeloid Leukemia (CML) therapy with imatinib. The focus lies in elucidating the allergic reactions induced by imatinib, specifically its impact on T helper (Th) cell...

  • Article
  • Open Access
10 Citations
2,189 Views
19 Pages

Modeling of a Double Gas Hydrate Particle Ignition

  • Olga Gaidukova,
  • Sergey Misyura,
  • Dmitrii Razumov and
  • Pavel Strizhak

11 June 2022

This paper presents the numerical research findings for the conditions and characteristics of methane-propane hydrate particle ignition. The curves of the ignition delay times of a hydrate particle versus its size and ambient temperature were obtaine...

  • Article
  • Open Access
7 Citations
4,556 Views
24 Pages

Effects of Viral and Cytokine Delays on Dynamics of Autoimmunity

  • Farzad Fatehi,
  • Yuliya N. Kyrychko and
  • Konstantin B. Blyuss

28 April 2018

A major contribution to the onset and development of autoimmune disease is known to come from infections. An important practical problem is identifying the precise mechanism by which the breakdown of immune tolerance as a result of immune response to...

  • Article
  • Open Access
6 Citations
3,561 Views
19 Pages

Robust, spontaneous pacemaker activity originating in the sinoatrial node (SAN) of the heart is essential for cardiovascular function. Anatomical, electrophysiological, and molecular methods as well as mathematical modeling approaches have quite thor...

  • Article
  • Open Access
1 Citations
1,604 Views
36 Pages

21 September 2025

This paper examines solutions to mathematical models based on functional-differential equations, which have applications in immunology. This new approach allows us to study discontinuous solutions that more accurately depict real-world phenomena. It...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,667 Views
24 Pages

Analysis of Within-Host Mathematical Models of Toxoplasmosis That Consider Time Delays

  • Sharmin Sultana,
  • Gilberto González-Parra and
  • Abraham J. Arenas

28 October 2023

In this paper, we investigate two within-host mathematical models that are based on differential equations. These mathematical models include healthy cells, tachyzoites, and bradyzoites. The first model is based on ordinary differential equations and...

  • Article
  • Open Access
7 Citations
3,193 Views
15 Pages

Mathematical Modelling to Predict the Effect of Vaccination on Delay and Rise of COVID-19 Cases Management

  • Charu Arora,
  • Poras Khetarpal,
  • Saket Gupta,
  • Nuzhat Fatema,
  • Hasmat Malik and
  • Asyraf Afthanorhan

6 February 2023

In this paper, a mathematical model based on COVID-19 is developed to study and manage disease outbreaks. The effect of vaccination with regard to its efficacy and percentage of population vaccinated in a closed population is investigated. To study v...

  • Article
  • Open Access
1 Citations
1,850 Views
20 Pages

Transient Analysis of Fault-Induced Delayed Voltage Recovery by Mathematical Modeling of a Three-Phase Induction Motor

  • Sebastian Loaiza-Estrada,
  • Juan P. Mesa-Beleño,
  • Karen Lemmel-Vélez,
  • Sergio A. Estrada-Mesa,
  • Carlos A. Valencia-Hernandez,
  • Jose R. Velasco-Méndez and
  • Marco A. Monsalve-Cadavid

This paper presents a detailed fifth-order mathematical model of a three-phase induction motor, used in the WECC (Western Electricity Coordinating Council) composite load model. The main objective is to analyze the dynamic behavior of three-phase ind...

  • Article
  • Open Access
6 Citations
2,681 Views
22 Pages

19 April 2023

Most biological processes take time to occur. In infectious diseases, such as malaria or chikungunya, there is a period of time between when a susceptible individual gets bitten by the vector, and when the individual develops the disease. These times...

  • Article
  • Open Access
14 Citations
4,247 Views
26 Pages

14 September 2021

This article considers an inventory model for non-instantaneous deteriorating items with expiration dates, such as seasonal items, first-hand vegetables, and fruits. Interestingly, an inspection will be performed to manage the quality of the items du...

  • Article
  • Open Access
795 Views
19 Pages

The application of contagion risk spread modeling within the banking sector is a relatively recent development, emerging as a response to the persistent threat of liquidity risk that has affected financial institutions globally. Liquidity risk is rec...

  • Article
  • Open Access
11 Citations
2,462 Views
19 Pages

A Numerical Study of the Dynamics of Vector-Born Viral Plant Disorders Using a Hybrid Artificial Neural Network Approach

  • Hosam Alhakami,
  • Muhammad Umar,
  • Muhammad Sulaiman,
  • Wajdi Alhakami and
  • Abdullah Baz

22 October 2022

Most plant viral infections are vector-borne. There is a latent period of disease inside the vector after obtaining the virus from the infected plant. Thus, after interacting with an infected vector, the plant demonstrates an incubation time before b...

  • Article
  • Open Access
38 Citations
6,304 Views
16 Pages

Modeling and Forecasting of COVID-19 Spreading by Delayed Stochastic Differential Equations

  • Marouane Mahrouf,
  • Adnane Boukhouima,
  • Houssine Zine,
  • El Mehdi Lotfi,
  • Delfim F. M. Torres and
  • Noura Yousfi

7 February 2021

The novel coronavirus disease (COVID-19) pneumonia has posed a great threat to the world recent months by causing many deaths and enormous economic damage worldwide. The first case of COVID-19 in Morocco was reported on 2 March 2020, and the number o...

  • Article
  • Open Access
4 Citations
1,750 Views
36 Pages

Existence of Traveling Waves of a Diffusive Susceptible–Infected–Symptomatic–Recovered Epidemic Model with Temporal Delay

  • Julio C. Miranda,
  • Abraham J. Arenas,
  • Gilberto González-Parra and
  • Luis Miguel Villada

28 February 2024

The aim of this article is to investigate the existence of traveling waves of a diffusive model that represents the transmission of a virus in a determined population composed of the following populations: susceptible (S), infected (I), asymptomatic...

  • Review
  • Open Access
1,478 Views
22 Pages

5 December 2024

Computational modeling and the theory of nonlinear dynamical systems allow us not only to simply describe the events of biochemical oscillators in the ethanol fermentation process but also to understand why these events occur. This article reviews re...

  • Article
  • Open Access
4 Citations
2,624 Views
15 Pages

Mathematical Modeling of the Tumor–Immune System with Time Delay and Diffusion

  • Amina Cherraf,
  • Mingchu Li,
  • Anes Moulai-Khatir and
  • Meryem Hamidaoui

10 February 2023

This paper proposes a partial differential equation model based on the model introduced by V. A. Kuznetsov and M. A. Taylor, which explains the dynamics of a tumor–immune interaction system, where the immune reactions are described by a Michael...

  • Article
  • Open Access
10 Citations
2,369 Views
22 Pages

Extensive research was conducted on the transmission dynamics of tuberculosis epidemics during its reemergence from the 1980s to the early 1990s, but this global problem of investigating tuberculosis spread dynamics remains of paramount importance. O...

  • Article
  • Open Access
8 Citations
2,635 Views
20 Pages

28 January 2021

In this paper, we obtain sufficient conditions for the persistence and permanence of a family of nonautonomous systems of delay differential equations. This family includes structured models from mathematical biology, with either discrete or distribu...

  • Article
  • Open Access
9 Citations
6,002 Views
18 Pages

2 November 2017

Bad weather, mechanical failures, air control, and crew members of the discomfort health are very likely to cause flight delays. If these events occur, decision-makers of airport operation must rediscover the flight schedules through reassigning gate...

  • Article
  • Open Access
22 Citations
2,565 Views
21 Pages

19 January 2023

This work investigates a mathematical fractional-order model that depicts the Caputo growth of a new coronavirus (COVID-19). We studied the existence and uniqueness of the linked solution using the fixed point theory method. Using the Laplace Adomian...

  • Article
  • Open Access
5 Citations
2,063 Views
21 Pages

28 August 2023

Forest pests and diseases have been seriously threatening ecological security. Effective prevention and control of such threats can extend the growth cycle of forest trees and increase the amount of forest carbon sink, which makes a contribution to a...

  • Article
  • Open Access
9 Citations
6,093 Views
17 Pages

27 January 2023

Production delays are significant problems for the loss of goodwill of the customers and the loss of profits associated with them. The delays may accrue as a result of insufficient resource planning and poorly designed unsatisfactory procedures. In t...

  • Article
  • Open Access
1 Citations
336 Views
19 Pages

In this article, we investigate a nonlinear ψ-Hilfer fractional order Volterra integro-delay differential equation (ψ-Hilfer FRVIDDE) and a nonlinear ψ-Hilfer fractional Volterra delay integral equation (ψ-Hilfer FRVDIE), both of whic...

  • Article
  • Open Access
17 Citations
2,765 Views
28 Pages

Global Stability of a Humoral Immunity COVID-19 Model with Logistic Growth and Delays

  • Ahmed M. Elaiw,
  • Abdullah J. Alsaedi,
  • Afnan Diyab Al Agha and
  • Aatef D. Hobiny

28 May 2022

The mathematical modeling and analysis of within-host or between-host coronavirus disease 2019 (COVID-19) dynamics are considered robust tools to support scientific research. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause o...

  • Article
  • Open Access
14 Citations
4,249 Views
18 Pages

18 November 2020

The article deals with the influence of the infrastructure for public transport on the delay time of private and public transport in the city. The study employed the methods of simulation, mathematical modeling and field research. Imitation microscop...

  • Article
  • Open Access
10 Citations
3,212 Views
13 Pages

Decoupling Adaptive Smith Prediction Model of Flatness Closed-Loop Control and Its Application

  • Mingming Song,
  • Hongmin Liu,
  • Yanghuan Xu,
  • Dongcheng Wang and
  • Yangyang Huang

26 July 2020

Flatness control system is characterized by multi-parameters, strong coupling, pure time delay, which complicate the establishment of an accurate mathematical model. Therefore, a control scheme that combines dynamic decoupling, PI (Proportion and Int...

  • Article
  • Open Access
2 Citations
2,286 Views
15 Pages

12 October 2022

The calculation of the probability of a minor outbreak is crucial in analyzing a stochastic epidemic model. For stochastic epidemic models with fixed delays, the linear chain trick is applied to transform the delayed models into a family of ODE model...

  • Feature Paper
  • Article
  • Open Access
10 Citations
2,665 Views
15 Pages

Solving Linear and Nonlinear Delayed Differential Equations Using the Lambert W Function for Economic and Biological Problems

  • Tomas Ruzgas,
  • Irma Jankauskienė,
  • Audrius Zajančkauskas,
  • Mantas Lukauskas,
  • Matas Bazilevičius,
  • Rugilė Kaluževičiūtė and
  • Jurgita Arnastauskaitė

6 September 2024

Studies of the dynamics of linear and nonlinear differential equations with delays described by mathematical models play a crucial role in various scientific domains, including economics and biology. In this article, the Lambert function method, whic...

  • Article
  • Open Access
9 Citations
5,266 Views
13 Pages

2 November 2018

The delaying mechanism is an important part of micro-electro-mechanical systems (MEMS) devices. However, very few mechanical delaying mechanisms are available. In this paper, an elastic-beam delaying mechanism has been proposed innovatively through e...

  • Article
  • Open Access
6 Citations
2,061 Views
27 Pages

9 August 2023

This study proposes a mathematical model that accounts for the interaction of bacteria, phages, and the innate immune response with a discrete time delay. First, for the non-delayed model we determine the local and global stability of various equilib...

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