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1,039 Results Found

  • Proceeding Paper
  • Open Access
1,428 Views
17 Pages

26 November 2024

Analog computing had its prime in the years from 1960 to 1970. With the rise of powerful digital computers, analog computing using transistor and Operational Amplififer (OPAMP) circuits vanished nearly completely but gained an increasing interest in...

  • Review
  • Open Access
1 Citations
7,005 Views
26 Pages

A Survey of Analog Computing for Domain-Specific Accelerators

  • Leonid Belostotski,
  • Asif Uddin,
  • Arjuna Madanayake and
  • Soumyajit Mandal

Analog computing has re-emerged as a powerful tool for solving complex problems in various domains due to its energy efficiency and inherent parallelism. This paper summarizes recent advancements in analog computing, exploring discrete time and conti...

  • Review
  • Open Access
23 Citations
7,417 Views
22 Pages

Optical Realization of Wave-Based Analog Computing with Metamaterials

  • Kaiyang Cheng,
  • Yuancheng Fan,
  • Weixuan Zhang,
  • Yubin Gong,
  • Shen Fei and
  • Hongqiang Li

25 December 2020

Recently, the study of analog optical computing raised renewed interest due to its natural advantages of parallel, high speed and low energy consumption over conventional digital counterpart, particularly in applications of big data and high-throughp...

  • Communication
  • Open Access
14 Citations
5,589 Views
11 Pages

Large-Scale Reconfigurable Integrated Circuits for Wideband Analog Photonic Computing

  • Yuhan Yao,
  • Yanxian Wei,
  • Jianji Dong,
  • Ming Li and
  • Xinliang Zhang

Photonic integrated circuits (PICs) have been a research hotspot in recent years. Programmable PICs that have the advantages of versatility and reconfigurability that can realize multiple functions through a common structure have been especially popu...

  • Review
  • Open Access
8 Citations
5,125 Views
18 Pages

The Role of Phase-Change Memory in Edge Computing and Analog In-Memory Computing: An Overview of Recent Research Contributions and Future Challenges

  • Alessio Antolini,
  • Francesco Zavalloni,
  • Andrea Lico,
  • Said Quqa,
  • Lorenzo Greco,
  • Mauro Mangia,
  • Fabio Pareschi,
  • Marco Pasotti and
  • Eleonora Franchi Scarselli

9 June 2025

Phase Change Memory (PCM) has emerged as a promising non-volatile memory technology with significant applications in both edge computing and analog in-memory computing. This paper synthesizes recent research contributions on the use of PCM for smart...

  • Article
  • Open Access
19 Citations
2,963 Views
19 Pages

Characterization and Programming Algorithm of Phase Change Memory Cells for Analog In-Memory Computing

  • Alessio Antolini,
  • Eleonora Franchi Scarselli,
  • Antonio Gnudi,
  • Marcella Carissimi,
  • Marco Pasotti,
  • Paolo Romele and
  • Roberto Canegallo

26 March 2021

In this paper, a thorough characterization of phase-change memory (PCM) cells was carried out, aimed at evaluating and optimizing their performance as enabling devices for analog in-memory computing (AIMC) applications. Exploiting the features of pro...

  • Article
  • Open Access
1 Citations
2,899 Views
12 Pages

Analog computing from recycling principle for next circular economy scenario has been studied with an iron oxide-coupled graphite/Fe–Si steel structure which was built using recycled waste materials, such as lead pencil and 3% Si steel (Fe–Si steel)...

  • Article
  • Open Access
1,292 Views
20 Pages

14 October 2025

Deep neural networks (DNNs) require efficient hardware accelerators due to the high cost of vector–matrix multiplication operations. Computing-in-memory (CIM) architectures address this challenge by performing computations directly within memor...

  • Article
  • Open Access
1,769 Views
21 Pages

17 April 2025

Edge-computing applications demand ultra-low-power architectures for both feature extraction and classification tasks. In this manuscript, a Keyword Spotting (KWS) system tailored for energy-constrained portable environments is proposed. A 16-channel...

  • Article
  • Open Access
3 Citations
3,922 Views
17 Pages

8 June 2022

This paper proposes a low-computing-complexity touch signal detection method and analog front-end (AFE) circuits based on cross-correlation technology for large mutual capacitance touch screen panels (TSPs). To solve the traditional touch signal dete...

  • Article
  • Open Access
1,971 Views
29 Pages

This article presents an energy-efficient IC architecture implementation of an analog image-processing ML system, where the primary issue is analog architecture development for existing energy-efficient analog computing devices. An architecture is de...

  • Article
  • Open Access
5 Citations
3,742 Views
18 Pages

30 July 2023

Analogy-based learning methods map the concept being learned to a concept well understood by the learner. An analogy is primarily useful when learners do not know the topic being studied. Computer science is an area where the concepts exhibit a high...

  • Article
  • Open Access
17 Citations
10,175 Views
22 Pages

The focus of this work is to develop a starting framework for analog numerical analysis and related algorithm questions. Digital computation is enabled by a framework developed over the last 80 years. Having an analog framework enables wider capabili...

  • Article
  • Open Access
2 Citations
4,296 Views
17 Pages

30 March 2023

This paper describes a design process for a universal development kit based on an analog computer concept that can model the dynamics of an arbitrarily complex dynamical system up to the fourth order. The constructed development kit contains digital...

  • Article
  • Open Access
959 Views
22 Pages

Computational Play in Early Childhood: Integrating Analog and Digital Tools to Support Mathematical Learning and Computational Thinking

  • Eva Brooks,
  • Camilla Finsterbach Kaup,
  • Susanne Dau,
  • Emma Edstrand,
  • Francesca Granone and
  • Elin Kirsti Lie Reikerås

27 November 2025

Although play naturally embeds computational thinking (CT) and mathematical learning in early childhood education, designing developmentally appropriate learning activities that purposefully nurture and extend these competencies remains a challenge....

  • Article
  • Open Access
71 Citations
8,865 Views
14 Pages

Bipolar Analog Memristors as Artificial Synapses for Neuromorphic Computing

  • Rui Wang,
  • Tuo Shi,
  • Xumeng Zhang,
  • Wei Wang,
  • Jinsong Wei,
  • Jian Lu,
  • Xiaolong Zhao,
  • Zuheng Wu,
  • Rongrong Cao and
  • Ming Liu
  • + 2 authors

26 October 2018

Synaptic devices with bipolar analog resistive switching behavior are the building blocks for memristor-based neuromorphic computing. In this work, a fully complementary metal-oxide semiconductor (CMOS)-compatible, forming-free, and non-filamentary m...

  • Article
  • Open Access
14 Citations
8,547 Views
24 Pages

This paper shows the first step in analog (and mixed signal) abstraction utilized in large-scale Field Programmable Analog Arrays (FPAA), encoded in the open-source SciLab/Xcos based toolset. Having any opportunity of a wide-scale utilization of ultr...

  • Article
  • Open Access
16 Citations
11,814 Views
33 Pages

31 July 2018

Multimeters are useful instruments for measuring electronic parameters. Even though the digital multimeter is commonly used in our daily life under the considerations of precision and cost, the analog multimeter is still preferable in many applicatio...

  • Article
  • Open Access
12 Citations
4,187 Views
20 Pages

Analog System High-Level Synthesis for Energy-Efficient Reconfigurable Computing

  • Afolabi Ige,
  • Linhao Yang,
  • Hang Yang,
  • Jennifer Hasler and
  • Cong Hao

The design of analog computing systems requires significant human resources and domain expertise due to the lack of automation tools to enable these highly energy-efficient, high-performance computing nodes. This work presents the first automated too...

  • Editorial
  • Open Access
1,828 Views
6 Pages

The leading theme of the 2019 Summit of International Society for the Study of Information held 2–6 June 2019 at The University of California at Berkeley was the question “Where is the I in AI and the meaning of Information?” The question addresses o...

  • Article
  • Open Access
2 Citations
3,758 Views
11 Pages

Evaluation of the Effect of Topical Prostaglandin Analog Treatment on Orbital Structures in Open-Angle Glaucoma with Computed Tomography

  • Berire Şeyma Durmuş Ece,
  • Zübeyir Yozgat,
  • Hüseyin Bayramlı,
  • Bunyamin Ece and
  • Sonay Aydin

28 September 2024

Background/Objectives: This study aims to evaluate the computed tomography (CT) scans of glaucoma patients using prostaglandin analogs (PGA) in one eye, investigate findings associated with prostaglandin-associated periorbitopathy (PAP), and compare...

  • Article
  • Open Access
3 Citations
2,127 Views
10 Pages

An Ultra-Low-Power Analog Multiplier–Divider Compatible with Digital Code for RRAM-Based Computing-in-Memory Macros

  • Yiming Yang,
  • Shidong Lv,
  • Xiaoran Li,
  • Xinghua Wang,
  • Qian Wang,
  • Yiyang Yuan,
  • Sen Liang and
  • Feng Zhang

24 July 2023

This manuscript presents an ultra-low-power analog multiplier–divider compatible with digital code words, which is applicable to the integrated structure of resistive random-access memory (RRAM)-based computing-in-memory (CIM) macros. Current m...

  • Article
  • Open Access
23 Citations
10,716 Views
38 Pages

This discussion develops a theoretical analog architecture framework similar to the well developed digital architecture theory. Designing analog systems, whether small or large scale, must optimize their architectures for energy consumption. As in di...

  • Article
  • Open Access
2 Citations
2,931 Views
12 Pages

ACIMS: Analog CIM Simulator for DNN Resilience

  • Dong Ding,
  • Lei Wang,
  • Zhijie Yang,
  • Kai Hu and
  • Hongjun He

Analog Computing In Memory (ACIM) combines the advantages of both Compute In Memory (CIM) and analog computing, making it suitable for the design of energy-efficient hardware accelerators for computationally intensive DNN applications. However, their...

  • Communication
  • Open Access
3 Citations
4,766 Views
11 Pages

A Spiking Neural Network (SNN) is realized within a 65 nm CMOS process to demonstrate the feasibility of its constituent cells. Analog hardware neural networks have shown improved energy efficiency in edge computing for real-time-inference applicatio...

  • Article
  • Open Access
8 Citations
2,902 Views
10 Pages

Metasurface-Based Quantum Searcher on a Silicon-On-Insulator Chip

  • Zeyong Wei,
  • Haoyu Li,
  • Linyuan Dou,
  • Lingyun Xie,
  • Zhanshan Wang and
  • Xinbin Cheng

28 July 2022

Optical analog computing has natural advantages of parallel computation, high speed and low energy consumption over traditional digital computing. To date, research in the field of on-chip optical analog computing has mainly focused on classical math...

  • Article
  • Open Access
11 Citations
5,178 Views
21 Pages

Physical computing unifies real value computing including analog, neuromorphic, optical, and quantum computing. Many real-valued techniques show improvements in energy efficiency, enable smaller area per computation, and potentially improve algorithm...

  • Article
  • Open Access
10 Citations
6,429 Views
20 Pages

Large-scale field-programmable analog arrays (FPAA) have the potential to handle machine inference and learning applications with significantly low energy requirements, potentially alleviating the high cost of these processes today, even in cloud-bas...

  • Article
  • Open Access
3 Citations
2,625 Views
23 Pages

Exploration of the Binding Mechanism of Cyclic Dinucleotide Analogs to Stimulating Factor Proteins and the Implications for Subsequent Analog Drug Design

  • Shu-Wei Yuan,
  • Hong-Ling Shi,
  • Mu-Ran Fu,
  • Xi-Chuan Zhang,
  • Xiao-Qi Xi,
  • Yao Wang,
  • Tai-Song Shen,
  • Jin-Liang Ma and
  • Cun-Duo Tang

14 March 2024

Cyclic dinucleotides (CDNs) are cyclic molecules consisting of two nucleoside monophosphates linked by two phosphodiester bonds, which act as a second messenger and bind to the interferon gene stimulating factor (STING) to activate the downstream sig...

  • Review
  • Open Access
1 Citations
5,544 Views
16 Pages

Structural Innovations in Vancomycin: Overcoming Resistance and Expanding the Antibacterial Spectrum

  • Ricardo Cartes-Velásquez,
  • Felipe Morales-León,
  • Franco Valdebenito-Maturana,
  • Pablo Sáez-Riquelme,
  • Nicolás Rodríguez-Ortíz and
  • Hernán Carrillo-Bestagno

23 June 2025

Vancomycin, a cornerstone antibiotic against severe Gram-positive infections, is increasingly challenged by resistance in Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin Enterococcus spp. (VRE), necessitating the development of nove...

  • Proceeding Paper
  • Open Access
2,056 Views
5 Pages

According to the currently dominant view, cognitive science is a study of mind and intelligence focused on computational models of knowledge in humans. It is described in terms of symbol manipulation over formal language. This approach is connected w...

  • Article
  • Open Access
27 Citations
7,494 Views
17 Pages

Design of New α-Conotoxins: From Computer Modeling to Synthesis of Potent Cholinergic Compounds

  • Igor E. Kasheverov,
  • Maxim N. Zhmak,
  • Alexey Y. Khruschov and
  • Victor I. Tsetlin

28 September 2011

A series of 14 new analogs of α-conotoxin PnIA Conus pennaceus was synthesized and tested for binding to the human α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine-binding proteins (AChBP) Lymnaea stagnalis and Aplysia californica. Based...

  • Article
  • Open Access
995 Views
26 Pages

29 March 2025

One of the fundamental problems of information theory, since its foundation by C. Shannon, has been the computation of the capacity of a discrete memoryless channel, a quantity expressing the maximum rate at which information can travel through the c...

  • Article
  • Open Access
3 Citations
4,656 Views
14 Pages

27 November 2017

Flexible electronic devices, such as the typical thin-film transistors, are widely adopted in the area of sensors, displayers, wearable equipment, and such large-area applications, for their features of bending and stretching; additionally, in some a...

  • Article
  • Open Access
3 Citations
3,486 Views
14 Pages

A Switched Capacitor Memristor Emulator Using Stochastic Computing

  • Carola de Benito,
  • Oscar Camps,
  • Mohamad Moner Al Chawa,
  • Stavros G. Stavrinides and
  • Rodrigo Picos

Due to the increased use of memristors and their many applications, the use of emulators has grown in parallel to avoid some of the difficulties presented by real devices, such as variability and reliability. In this paper, we present a memristive em...

  • Article
  • Open Access
4 Citations
3,358 Views
20 Pages

13 June 2024

We explore security aspects of a new computing paradigm that combines novel memristors and traditional Complimentary Metal Oxide Semiconductor (CMOS) to construct a highly efficient analog and/or digital fabric that is especially well-suited to Machi...

  • Feature Paper
  • Review
  • Open Access
3 Citations
2,485 Views
12 Pages

28 June 2023

In this review, we establish a relation between information erasure and continuous phase transitions. The order parameter, which characterizes these transitions, measures the order of the systems. It varies between 0, when the system is completely di...

  • Article
  • Open Access
5 Citations
6,204 Views
25 Pages

19 August 2022

Charles Babbage’s Analytical Engine can be recollected as a fossilized image of the first digital computer. It is essentially distinguished from all prior and analog computers by the transcription of the ‘mechanical notation’, the s...

  • Article
  • Open Access
4 Citations
3,316 Views
13 Pages

Decoding Algorithms and HW Strategies to Mitigate Uncertainties in a PCM-Based Analog Encoder for Compressed Sensing

  • Carmine Paolino,
  • Alessio Antolini,
  • Francesco Zavalloni,
  • Andrea Lico,
  • Eleonora Franchi Scarselli,
  • Mauro Mangia,
  • Alex Marchioni,
  • Fabio Pareschi,
  • Gianluca Setti and
  • Marco Pasotti
  • + 3 authors

Analog In-Memory computing (AIMC) is a novel paradigm looking for solutions to prevent the unnecessary transfer of data by distributing computation within memory elements. One such operation is matrix-vector multiplication (MVM), a workhorse of many...

  • Article
  • Open Access
2 Citations
2,486 Views
22 Pages

The model presented by Gabriel Kron in 1945 is an example of an analog computer simulating quantum phenomena on a hardware level. It uses passive RLC elements to construct a hardware solver for the problem of quantum particles confined by rectangular...

  • Article
  • Open Access
4 Citations
3,215 Views
17 Pages

CIM-Based Smart Pose Detection Sensors

  • Jyun-Jhe Chou,
  • Ting-Wei Chang,
  • Xin-You Liu,
  • Tsung-Yen Wu,
  • Yu-Kai Chen,
  • Ying-Tuan Hsu,
  • Chih-Wei Chen,
  • Tsung-Te Liu and
  • Chi-Sheng Shih

4 May 2022

The majority of digital sensors rely on von Neumann architecture microprocessors to process sampled data. When the sampled data require complex computation for 24×7, the processing element will a consume significant amount of energy and computa...

  • Article
  • Open Access
9 Citations
2,889 Views
14 Pages

On-Chip Optical Adder and Differential-Equation-Solver Based on Fourier Optics and Metasurface

  • Yutai Chen,
  • Huan Chen,
  • Hansi Ma,
  • Zhaojian Zhang,
  • Wanlin Xie,
  • Xin Li,
  • Jian Chen and
  • Junbo Yang

30 September 2022

Analog optical computing (AOC) has attracted great attention over the past few years, because of its ultra-high speed (potential for real-time processing), ultra-low power consumption, and parallel processing capabilities. In this article, we design...

  • Article
  • Open Access
5 Citations
6,113 Views
14 Pages

This study presents a charge-domain SRAM-based in-memory computing (IMC) architecture. The multiply-and-accumulate (MAC) operation in the IMC structure is divided into current- and charge-domain methods. Current-domain IMC has high-power consumption...

  • Article
  • Open Access
8 Citations
4,244 Views
21 Pages

Discovery Model Based on Analogies for Teaching Computer Programming

  • Javier Alejandro Jiménez Toledo,
  • César A. Collazos and
  • Manuel Ortega

11 June 2021

Teaching the fundamentals of computer programming in a first course (CS1) is a complex activity for the professor and is also a challenge for them. Nowadays, there are several teaching strategies for dealing with a CS1 at the university, one of which...

  • Article
  • Open Access
44 Citations
10,976 Views
17 Pages

3 July 2018

The increased popularity of brain-computer interfaces (BCIs) has created a new demand for miniaturized and low-cost electroencephalogram (EEG) acquisition devices for entertainment, rehabilitation, and scientific needs. The lack of scientific analysi...

  • Article
  • Open Access
383 Views
33 Pages

18 December 2025

The proteasome β5 subunit plays a central role in protein degradation and is an established therapeutic target in glioblastoma. Marizomib (MZB), a natural β5 inhibitor, has shown promising anticancer activity, yet suboptimal pharmacological...

  • Article
  • Open Access
7 Citations
2,840 Views
14 Pages

End-to-End Solution for Analog Gauge Monitoring Using Computer Vision in an IoT Platform

  • João Peixoto,
  • João Sousa,
  • Ricardo Carvalho,
  • Gonçalo Santos,
  • Ricardo Cardoso and
  • Ana Reis

15 December 2023

The emergence of Industry 4.0 and 5.0 technologies has enabled the digital transformation of various processes and the integration of sensors with the internet. Despite these strides, many industrial sectors still rely on visual inspection of physica...

  • Article
  • Open Access
6 Citations
2,526 Views
12 Pages

Computational Analysis of SAM Analogs as Methyltransferase Inhibitors of nsp16/nsp10 Complex from SARS-CoV-2

  • Alessandra M. Balieiro,
  • Eduarda L. S. Anunciação,
  • Clauber H. S. Costa,
  • Wesam S. Qayed and
  • José Rogério A. Silva

12 November 2022

Methyltransferases (MTases) enzymes, responsible for RNA capping into severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are emerging important targets for the design of new anti-SARS-CoV-2 agents. Here, analogs of S-adenosylmethionine (SA...

  • Article
  • Open Access
21 Citations
5,956 Views
10 Pages

Low Computational Cost Distributed Acoustic Sensing Using Analog I/Q Demodulation

  • Fei Jiang,
  • Zixiao Lu,
  • Feida Cai,
  • Honglang Li,
  • Zhenhai Zhang,
  • Yixin Zhang and
  • Xuping Zhang

30 August 2019

Distributed acoustic sensing based on phase-sensitive optical time-domain reflectometry (Φ-OTDR) has been widely used in many fields. Phase demodulation of the Φ-OTDR signal is essential for undistorted acoustic measurement. Digital coherent...

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