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136 Results Found

  • Article
  • Open Access
75 Citations
7,209 Views
17 Pages

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key transcription factor against oxidative stress and neurodegenerative disorders. Phenylethanoid glycosides (PhGs; salidroside, acteoside, isoacteoside, and echinacoside) exhibit antioxidant an...

  • Article
  • Open Access
1,961 Views
17 Pages

Throughout human history, wild plant resources have played an invaluable role, serving as critical sources of food, medicine, and industrial materials. This study examined the callus cultures of Cistanche deserticola Y.C. Ma, a medicinal desert plant...

  • Article
  • Open Access
2 Citations
1,767 Views
18 Pages

Responsiveness of Candidate Genes on CoPv01CDRK/PhgPv01CDRK Loci in Common Bean Challenged by Anthracnose and Angular Leaf Spot Pathogens

  • Maike Lovatto,
  • Maria Celeste Gonçalves-Vidigal,
  • Mariana Vaz Bisneta,
  • Alexandre Catto Calvi,
  • Josmar Mazucheli,
  • Pedro Soares Vidigal Filho,
  • Eduardo Gomes Rosa Miranda and
  • Maeli Melotto

7 November 2023

Anthracnose (ANT) and angular leaf spot (ALS) are significant diseases in common bean, leading to considerable yield losses under specific environmental conditions. The California Dark Red Kidney (CDRK) bean cultivar is known for its resistance to mu...

  • Review
  • Open Access
122 Citations
14,707 Views
25 Pages

Phenylethanoid glycosides (PhGs) are widely distributed in traditional Chinese medicines as well as in other medicinal plants, and they were characterized by a phenethyl alcohol (C6-C2) moiety attached to a β-glucopyranose/β-allopyranose via a glycos...

  • Review
  • Open Access
28 Citations
4,521 Views
16 Pages

Research Progress and Trends of Phenylethanoid Glycoside Delivery Systems

  • Jin Huang,
  • Dandan Zhao,
  • Chaojing Cui,
  • Jianxiong Hao,
  • Zhentao Zhang and
  • Limin Guo

7 March 2022

Background: Phenylethanoid glycosides (PhGs) are obtained from a wide range of sources and show strong biological and pharmacological activities, such as antioxidant, antibacterial and neuroprotective effects. However, intestinal malabsorption and th...

  • Article
  • Open Access
17 Citations
3,820 Views
11 Pages

28 August 2019

Acanthus ilicifolius herb (AIH), the dry plant of Acanthus ilicifolius L., has long been used as a folk medicine for treating acute and chronic hepatitis. Phenylethanoid glycosides (PhGs) are one family of the main components in AIH with hepatoprotec...

  • Article
  • Open Access
1 Citations
1,591 Views
22 Pages

Integrated Metabolome, Transcriptome, and Physiological Analysis of the Flavonoid and Phenylethanol Glycosides Accumulation in Wild Phlomoides rotata Roots from Different Habitats

  • Zuxia Li,
  • Guigong Geng,
  • Chongxin Yin,
  • Lianyu Zhou,
  • Xiaozhuo Wu,
  • Jianxia Ma,
  • Rui Su,
  • Zirui Wang,
  • Feng Qiao and
  • Huichun Xie

Phlomoides rotata, a traditional medicinal plant, is commonly found on the Tibetan Plateau at altitudes of 3100–5200 m. Its primary active medicinal compounds, flavonoids and phenylethanol glycosides (PhGs), exhibit various pharmacological effe...

  • Abstract
  • Open Access
968 Views
1 Page

Scrophularia striata Boiss. (Scrophulariaceae family), as an important medicinal plant, is one of the species native to Western Iran. This perennial herbaceous plant has been traditionally used to cure various diseases, including eye and ear infectio...

  • Article
  • Open Access
1 Citations
705 Views
11 Pages

Alpine plants face intense ultraviolet (UV) radiation in high-altitude ecosystems, necessitating adaptive mechanisms like tyrosinase-mediated phenolic metabolism for UV protection. This study aimed to characterize the phenolic profile of Corallodiscu...

  • Article
  • Open Access
4 Citations
3,375 Views
19 Pages

Combined Metabolome and Transcriptome Analysis Highlights the Host’s Influence on Cistanche deserticola Metabolite Accumulation

  • Ru Feng,
  • Hongshuang Wei,
  • Rong Xu,
  • Sai Liu,
  • Jianhe Wei,
  • Kun Guo,
  • Haili Qiao and
  • Changqing Xu

The medicinal plant Cistanche deserticola Ma (Orobanchaceae) is a holoparasitic angiosperm that takes life-essential materials from Haloxylon ammodendron (C. A. Mey.) Bunge (Amaranthaceae) roots. Although many experiments have been conducted to impro...

  • Feature Paper
  • Article
  • Open Access
1,789 Views
12 Pages

Enzymatic β-Mannosylation of Phenylethanoid Alcohols

  • Lucia Černáková,
  • Peter Haluz,
  • Vladimír Mastihuba,
  • Zuzana Košťálová,
  • Elena Karnišová Potocká and
  • Mária Mastihubová

19 January 2025

Phenylethanoid glycosides (PhGs) are widely occurring secondary metabolites of medicinal plants with interesting biological activities such as antioxidant, anti-inflammatory, neuroprotective, antiviral, hepatoprotective, immunomodulatory, etc. They a...

  • Review
  • Open Access
630 Views
26 Pages

Due to the neuroprotective and antioxidant properties, phenylethanoid glycosides (PhGs) are valuable plant-derived compounds. Traditional extraction methods are constrained by low yields and limited resources, prompting the integration of synthetic b...

  • Article
  • Open Access
2 Citations
7,401 Views
23 Pages

30 April 2024

In non-Markovian tandem queueing networks the output process of one site, which is the input process to the next site, is not renewal. Consequently, the correlation analysis of that output processes is essential when studying such networks. A correla...

  • Article
  • Open Access
33 Citations
6,209 Views
21 Pages

20 November 2017

In this study, a sensitive ultra-performance liquid chromatography-photodiode array coupled to quadruple time-of-flight mass (UPLC-PDA-Q/TOF-MS) method and a 1,1-diphenyl-2- picrylhydrazyl (DPPH)-based assay were used to determine the chemical consti...

  • Article
  • Open Access
1 Citations
1,512 Views
13 Pages

Anti-Obesity Effect of Fresh and Browned Magnolia denudata Flowers in 3T3-L1 Adipocytes

  • Deok Jae Lee,
  • Jae Ho Yeom,
  • Yong Kwon Lee,
  • Yong Hoon Joo and
  • Namhyun Chung

11 October 2024

The major components of magnolia flower extracts (MFEs) were classified into four substances, such as flavonoids, phenylethanoid glycoside derivatives (PhGs), caffeoylquinic acids (CQAs), and others, in our previous study. The chemical components of...

  • Review
  • Open Access
6 Citations
4,948 Views
23 Pages

Bioactive Components, Pharmacological Properties, and Applications of Cistanche deserticola Y. C. Ma: A Comprehensive Review

  • Xiaofeng Liu,
  • Zichao Yang,
  • Minjun Han,
  • Yao Zhang,
  • Hussain Muhammad,
  • Hao Zhong and
  • Rongfa Guan

29 April 2025

Cistanche deserticola Y. C. Ma (C. deserticola), a holoparasitic desert plant traditionally revered as “desert ginseng”, has emerged as a versatile resource with significant applications in both medicinal and dietary contexts. This comprehensive revi...

  • Proceeding Paper
  • Open Access
4 Citations
2,560 Views
6 Pages

Diabetes mellitus (DM) is a chronic metabolic disorder and is associated with impaired wound healing. Non-healing leg and foot ulcers are a frequent significant consequence of diabetes and are caused by a combination of inadequate tissue perfusion, s...

  • Article
  • Open Access
1 Citations
5,224 Views
22 Pages

New Application of an Old Drug: Anti-Diabetic Properties of Phloroglucinol

  • Krzysztof Drygalski,
  • Mateusz Maciejczyk,
  • Urszula Miksza,
  • Andrzej Ustymowicz,
  • Joanna Godzień,
  • Angelika Buczyńska,
  • Andrzej Chomentowski,
  • Iga Walczak,
  • Karolina Pietrowska and
  • Edyta Adamska-Patruno
  • + 12 authors

24 September 2024

Phloroglucinol (PHG), an analgesic and spasmolytic drug, shows promise in preventing high-fat-diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) and insulin resistance. In Wistar rats, 10 weeks of PHG treatment did not prevent HFD-induced w...

  • Article
  • Open Access
1 Citations
11,091 Views
12 Pages

Premature Hair Graying and Its Associated Factors Among Medical Students and Resident Physicians at Imam Abdulrahman Bin Faisal University

  • Inaam B. Aldamanhori,
  • Nada J. Alghamdi,
  • Sadan M. Alharbi,
  • Shadan A. Aljarri,
  • Haya A. AlHemli and
  • Moataza M. Abdel Wahab

Background: Premature hair graying (PHG) is one of the most prevalent conditions affecting individuals worldwide. It has been recognized as an important cause of low self-esteem, with a significant physical and social impact. This study investigated...

  • Article
  • Open Access
5 Citations
3,962 Views
11 Pages

The Impact of Partial Splenic Embolization on Portal Hypertensive Gastropathy in Cirrhotic Patients with Portal Hypertension

  • Michio Saeki,
  • Hironao Okubo,
  • Yusuke Takasaki,
  • Eisuke Nakadera,
  • Yuka Fukuo,
  • Hiroo Fukada,
  • Yuta Hotchi,
  • Hitoshi Maruyama,
  • Shigehiro Kokubu and
  • Kenichi Ikejima
  • + 2 authors

3 April 2023

This study investigated the impact of partial splenic embolization (PSE) on portal hypertensive gastropathy (PHG). We retrospectively analyzed endoscopic findings and the portal venous system of 31 cirrhotic patients with PHG. The improved group was...

  • Case Report
  • Open Access
5 Citations
8,381 Views
11 Pages

Primary Hepatic Gastrinoma Causing Zollinger-Ellison Syndrome: A Rare and Challenging Diagnosis

  • Adrian Harvey,
  • Janice L. Pasieka,
  • Hassan Al-Bisher and
  • Elijah Dixon

14 February 2012

The majority of gastrinomas causing Zollinger-Ellison syndrome (ZES) are located in the duodenum or the pancreas. Primary hepatic gastrinomas (PHG) are extremely rare and difficult to diagnose because the liver is the commonest site of metastatic dis...

  • Article
  • Open Access
14 Citations
3,833 Views
20 Pages

Seasonal Evolution of Size-Segregated Particulate Mercury in the Atmospheric Aerosol Over Terra Nova Bay, Antarctica

  • Silvia Illuminati,
  • Anna Annibaldi,
  • Sébastien Bau,
  • Claudio Scarchilli,
  • Virginia Ciardini,
  • Paolo Grigioni,
  • Federico Girolametti,
  • Flavio Vagnoni,
  • Giuseppe Scarponi and
  • Cristina Truzzi

31 August 2020

Size-fractionated particulate mercury (PHg) measurements were performed from November 2017 to January 2018 at Terra Nova Bay (Antarctica) for the first time. Samples were collected every 10 days by a six-stage high-volume cascade impactor with size c...

  • Article
  • Open Access
9 Citations
4,838 Views
15 Pages

Levels and Sources of Atmospheric Particle-Bound Mercury in Atmospheric Particulate Matter (PM10) at Several Sites of an Atlantic Coastal European Region

  • Jorge Moreda-Piñeiro,
  • Adrián Rodríguez-Cabo,
  • María Fernández-Amado,
  • María Piñeiro-Iglesias,
  • Soledad Muniategui-Lorenzo and
  • Purificación López-Mahía

27 December 2019

Atmospheric particle-bound mercury (PHg) quantification, at a pg m−3 level, has been assessed in particulate matter samples (PM10) at several sites (industrial, urban and sub-urban sites) of Atlantic coastal European region during 13 months by using...

  • Article
  • Open Access
2,029 Views
13 Pages

Impact of Endoscopic Band Ligation on Gastric Complications Associated with Portal Hypertension

  • Maria Luisa Gambardella,
  • Giulia Fabiano,
  • Rocco Spagnuolo,
  • Rosanna De Marco,
  • Ileana Luppino,
  • Giusi Franco,
  • Francesco Rettura,
  • Mario Verta,
  • Francesco Luzza and
  • Ludovico Abenavoli

Background/Objectives: Clinically significant portal hypertension (CSPH) in cirrhotic patients impacts mortality rates and quality of life. CSPH increases the risk of systemic decompensation and could predispose to the deterioration of portal hyperte...

  • Article
  • Open Access
39 Citations
8,950 Views
23 Pages

24 August 2015

A series of cellulose ampholytes (CAms), with substitution degrees of cationic groups (DSC) of 0.41, 0.79, and 1.08, and with a substitution degree of anionic groups of 0.68, was prepared from sodium carboxymethylcellulose by a cationization reaction...

  • Article
  • Open Access
1,317 Views
20 Pages

Impact of Grazing Tibetan Pigs on Soil Quality

  • Guoxin Wu,
  • Haoqi Wang,
  • Mengqi Duan,
  • Licuo Ze,
  • Shixiong Dong,
  • Huimin Zhang,
  • Kejun Wang,
  • Zhankun Tan and
  • Peng Shang

20 November 2024

Pig manure, as an organic fertilizer, can significantly affect soil nutrient content, pH, and electrical conductivity. Moreover, the accumulation of heavy metals in pig manure and their potential ecological risks are also important concerns in soil m...

  • Article
  • Open Access
7 Citations
3,186 Views
20 Pages

Mercury (Hg) contamination in the Gulf of Trieste (northern Adriatic Sea) due to mining activity in Idrija (Slovenia) still represents an issue of environmental concern. The Isonzo/Soča River’s freshwater inputs have been identified as the main sourc...

  • Article
  • Open Access
44 Citations
6,358 Views
12 Pages

4 August 2017

We report the fabrication and improved properties of crosslinked polyarylene ether nitrile (CPEN) interpenetrating with a zinc ion bridged graphene sheet (GS) and carbon nanotube (CNT) network (GS-Zn-CNT) (CPEN/GS-Zn-CNT). Graphene oxide (GO) and aci...

  • Article
  • Open Access
1 Citations
1,412 Views
13 Pages

Haplotype Analysis and Gene Pyramiding for Pre-Harvest Sprouting Resistance in White-Grain Wheat

  • Haibin Dong,
  • Cheng Kou,
  • Lin Hu,
  • Yan Li,
  • Yuhui Fang and
  • Chaojun Peng

The Huanghuai winter wheat region, China’s primary wheat-producing area, predominantly cultivates white-grained wheat. Pre-harvest sprouting (PHS) significantly impacts yield and quality, making the breeding of PHS-resistant varieties crucial f...

  • Article
  • Open Access
3 Citations
1,954 Views
19 Pages

Lewis Acid-Base Adducts of α-Amino Acid-Derived Silaheterocycles and N-Methylimidazole

  • Anne Seidel,
  • Robert Gericke,
  • Beate Kutzner and
  • Jörg Wagler

28 November 2023

In chloroform solution, the reaction of bis(tert-butylamino)dimethylsilane ((tBuNH)2SiMe2) and an α-amino acid (α-amino isobutyric acid, H2Aib; D-phenylglycine, H2Phg; L-valine, H2Val) in the presence of N-methylimidazole (NMI) gave rise...

  • Article
  • Open Access
1 Citations
2,177 Views
11 Pages

Right Ventricle Strain Assessed by 2-Dimensional Speckle Tracking Echocardiography (2D-STE) to Evaluate Pulmonary Hypertension in Dogs with Dirofilaria immitis

  • Jorge Isidoro Matos,
  • Sara Nieves García-Rodríguez,
  • Noelia Costa-Rodríguez,
  • Alicia Caro-Vadillo,
  • Elena Carretón and
  • José Alberto Montoya-Alonso

20 December 2023

Echocardiographic assessment of the right ventricle is helpful for analysing the pathophysiology of heartworm disease and detecting pulmonary hypertension (PH) in dogs. In veterinary cardiology, the study of myocardial deformation using two-dimension...

  • Article
  • Open Access
625 Views
19 Pages

Leveraging Transcriptome Insights and GsHZ4 Gene Expression to Improve Alkaline Tolerance in Lupinus angustifolius

  • Jixiang Tang,
  • Mengyu Liu,
  • Yujing Liu,
  • Xiaoyu Wang,
  • Xinlei Du,
  • Xinyao Liu,
  • Mengyue Zhou,
  • Honglin Mao,
  • Yixuan Feng and
  • Lei Cao
  • + 2 authors

7 November 2025

Soil alkalinity severely restricts the cultivation of Lupinus angustifolius, a valuable legume. Wild soybean (Glycine soja) is a leguminous plant with extremely strong alkaline resistance (pH 8.5). Transferring the alkali-tolerant genes from wild soy...

  • Article
  • Open Access
11 Citations
3,359 Views
16 Pages

Most nonsteroidal anti-inflammatory drugs (NSAIDs) present poor aqueous solubility, impairing their efficiency in physiological media. In this context, Low Transition Temperature Mixtures (LTTMs) are a promising platform to overcome drugs’ poor solub...

  • Article
  • Open Access
38 Citations
5,392 Views
8 Pages

Effects of Garlic Powder and Salt on Meat Quality and Microbial Loads of Rabbit Burgers

  • Simone Mancini,
  • Simona Mattioli,
  • Roberta Nuvoloni,
  • Francesca Pedonese,
  • Alessandro Dal Bosco and
  • Gisella Paci

31 July 2020

The aim of the research study was to evaluate the effects of a common culinary spice such as garlic powder and salt addition on the quality and microbial shelf life of rabbit meat burgers. Rabbit burgers were evaluated for pH, the colour parameters,...

  • Article
  • Open Access
85 Citations
17,670 Views
18 Pages

IgG Charge: Practical and Biological Implications

  • Danlin Yang,
  • Rachel Kroe-Barrett,
  • Sanjaya Singh and
  • Thomas Laue

14 March 2019

Practically, IgG charge can contribute significantly to thermodynamic nonideality, and hence to solubility and viscosity. Biologically, IgG charge isomers exhibit differences in clearance and potency. It has been known since the 1930s that all immuno...

  • Article
  • Open Access
333 Views
18 Pages

Genomic and Functional Characterization of Lytic Tlsvirus Bacteriophages Targeting Salmonella Infantis Isolated from Poultry Farms in Ecuador

  • Sandra Sevilla-Navarro,
  • Ignacio Samuel Gómez-Cano,
  • Ivette Castillo-Beckmann,
  • Santiago Ballaz,
  • Alexis Debut and
  • Esteban Fernández-Moreira

26 January 2026

Salmonella is responsible for millions of foodborne illnesses worldwide. The emergence of antibiotic-resistant Salmonella strains necessitates the development of alternatives for controlling this microorganism in the food supply chain. In Ecuador, Sa...

  • Article
  • Open Access
9 Citations
6,173 Views
16 Pages

Potato Preload Mitigated Postprandial Glycemic Excursion in Healthy Subjects: An Acute Randomized Trial

  • Wenqi Zhao,
  • Ying Zhou,
  • Yuqing Yuan,
  • Zhihong Fan,
  • Yixue Wu,
  • Anshu Liu and
  • Xuejiao Lu

10 September 2020

This study investigated the preload effect of the medium and high glycemic index (GI) potato, as well as the combination of partially hydrolyzed guar gum (HG) and potato, when ingested prior to a rice meal, on the iso-carbohydrate basis. In a randomi...

  • Article
  • Open Access
67 Citations
11,316 Views
11 Pages

12 September 2013

Magnetite, Fe3O4, is a promising anode material for lithium ion batteries due to its high theoretical capacity (924 mA h g−1), high density, low cost and low toxicity. However, its application as high capacity anodes is still hampered by poor cycling...

  • Article
  • Open Access
2 Citations
3,154 Views
11 Pages

Synthesis and Characterization of a Nano-Adsorbent Derivative Derived from Grape Seeds for Cadmium Ion Removal in an Aqueous Solution

  • Alaa Jasim Mohammed,
  • Mohd Hafiz Ibrahim,
  • Syaizwan Zahmir Zulkifli and
  • Jasim Mohammed Salman

15 October 2021

Grape seeds were utilized as a source for nanoparticle adsorbents. The objective of this work was to prepare a nano adsorbent from grape seeds (GS) and FeCl2. The physical and chemical properties of grape seed ferrous oxide nanoparticles (GS-IONPs) w...

  • Article
  • Open Access
1 Citations
2,126 Views
16 Pages

20 March 2024

The exact mechanisms of MS (multiple sclerosis) evolution are still unknown. However, the development of EAE (experimental autoimmune encephalomyelitis simulating human MS) in C57BL/6 mice occurs due to the violation of bone marrow hematopoietic stem...

  • Article
  • Open Access
5 Citations
2,886 Views
11 Pages

Odor ΨΩγemission has become mathvariant="normal" mathvariant="sans-serif-bold-italic" an important issue in kitchen waste management. Ammonia and hydrogen sulfide are the two most important odor sources as they contribute malodor and...

  • Article
  • Open Access
9 Citations
4,883 Views
16 Pages

6 November 2024

Butterfly pea flower (BPF), roselle calyx (RC), and grape skin (GS) are rich in bioactive phenolics with health benefits. Due to its simplicity, safety, and environmental friendliness, this study used water as a solvent to explore different extractio...

  • Article
  • Open Access
1,470 Views
12 Pages

11 August 2025

Bilirubin is a key component in the preparation of two traditional Chinese medicines: Calculus bovis sativus and Calculus bovis artifactus. Currently, industrial-scale production of bilirubin is limited to extraction from pig bile in a very low yield...

  • Article
  • Open Access
6 Citations
2,120 Views
14 Pages

Phase Angle, Inflammation, and Sarcopenia in Late Postoperative Roux-En-Y Gastric Bypass

  • Gisele Florêncio,
  • Aglécio Souza,
  • Elinton Chaim,
  • Allan Santos,
  • Louise Duran,
  • Camila Carvalho and
  • Sarah Monte Alegre

4 August 2023

Sarcopenic obesity is characterized by a disproportion between the amount of muscle to fat. Contrary to most studies evaluating parameters related to sarcopenic obesity in the elderly, this study aims to evaluate the phase angle (PhA) and sarcopenia...

  • Review
  • Open Access
7 Citations
6,898 Views
9 Pages

Gitelman’s syndrome (GS) and Bartter’s syndrome (BS) are rare inherited salt-losing tubulopathies whose variations in genotype do not correlate well with either clinical course or electrolyte requirements. Using GS/BS patients as nature&r...

  • Article
  • Open Access
21 Citations
5,832 Views
24 Pages

27 January 2021

High bicarbonate concentrations of calcareous soils with high pH can affect crop performance due to different constraints. Among these, Fe deficiency has mostly been studied. The ability to mobilize sparingly soluble Fe is a key factor for tolerance....

  • Article
  • Open Access
23 Citations
5,262 Views
17 Pages

Genome-Wide Association Study and Genomic Prediction on Plant Architecture Traits in Sweet Corn and Waxy Corn

  • Dongdong Dang,
  • Yuan Guan,
  • Hongjian Zheng,
  • Xuecai Zhang,
  • Ao Zhang,
  • Hui Wang,
  • Yanye Ruan and
  • Li Qin

9 January 2023

Sweet corn and waxy corn has a better taste and higher accumulated nutritional value than regular maize, and is widely planted and popularly consumed throughout the world. Plant height (PH), ear height (EH), and tassel branch number (TBN) are key pla...

  • Article
  • Open Access
3 Citations
2,639 Views
19 Pages

18 April 2020

It was recently shown that IgGs from sera of multiple sclerosis (MS) patients are active in the hydrolysis of DNA and myelin basic protein (MBP). We first analyzed the relative concentration of antibodies against five histones (H1, H2a, H2b, H3, and...

  • Article
  • Open Access
8 Citations
4,037 Views
20 Pages

Protein S-nitrosation is an important consequence of NO·metabolism with implications in physiology and pathology. The mechanisms responsible for S-nitrosation in vivo remain debatable and kinetic data on protein S-nitrosation by different age...

  • Article
  • Open Access
8 Citations
3,825 Views
18 Pages

Peptide segments with phenylalanine residues are commonly found in proteins that are related to neurodegenerative diseases. However, the self-assembly of phenylalanine-based peptides can be also functional. Peptides containing phenylalanine residues...

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