Medical Sciences Forum

22 pages, 1274 KiB

Open AccessConference Report

Abstracts of the X Forum on Translational Immunology and Cancer Immunotherapy (FIT Cancer 10)

by Francisco Aya, Luis de la Cruz, Delvys Rodríguez-Abreu, Luis Álvarez-Vallina, Manel Juan, Antonio José Conde-Moreno, Elisabeth Pérez-Ruiz, Xabier Mielgo and Ana Arance

Med. Sci. Forum 2025, 36(1), 1; https://doi.org/10.3390/msf2025036001 - 10 Jul 2025

Abstract

The Spanish Group for Cancer Immuno-Biotherapies (GÉTICA) held the X Forum on Translational Immunology and Cancer Immunotherapy (FIT Cancer 10) from 14 to 16 March 2024, in Seville (Spain). FIT Cancer is the largest meeting uniquely focused on cancer immunotherapy in Spain and [...] Read more.

The Spanish Group for Cancer Immuno-Biotherapies (GÉTICA) held the X Forum on Translational Immunology and Cancer Immunotherapy (FIT Cancer 10) from 14 to 16 March 2024, in Seville (Spain). FIT Cancer is the largest meeting uniquely focused on cancer immunotherapy in Spain and brings together clinicians and researchers, with expertise in the field of cancer immunology and immunotherapy. Here, we present abstracts submitted by GÉTICA’s members to the X Forum on Translational Immunology and Cancer Immunotherapy, which were divided into three topics: cell-based immunotherapies, novel therapeutic targets and strategies and clinical scenarios and potential biomarkers. Full article

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9 pages, 800 KiB

Open AccessProceeding Paper

Leveraging Digital Health for Pandemic Response: Reliable Telemonitoring and Personalized Patient Care

by Maria Montserrat Pérez García, Ainhoa Berasategi Artieda, Amaia Mendizabal Olaizola, Idoya Lizaso Vaquero, Francisco Diaz Tore, Macarena Sevilla, Ainhoa Bastarrika, Ainhoa Ariceta, Darya Chyzhyk, Maider Alberich and Manuel Millet Sampedro

Med. Sci. Forum 2025, 32(1), 5; https://doi.org/10.3390/msf2025032005 - 8 Jul 2025

Abstract

The COVID-19 pandemic exposed the urgent need for scalable, reliable telemedicine tools to manage mild cases remotely and avoid overburdening healthcare systems. This study evaluates StepCare, a remote monitoring medical device, during the first pandemic wave at a single center in Spain. Among [...] Read more.

The COVID-19 pandemic exposed the urgent need for scalable, reliable telemedicine tools to manage mild cases remotely and avoid overburdening healthcare systems. This study evaluates StepCare, a remote monitoring medical device, during the first pandemic wave at a single center in Spain. Among 35 patients monitored, StepCare showed high clinical reliability, aligning with physician assessments in 90.4% of cases. Patients and clinicians reported excellent usability and satisfaction. The system improved workflow efficiency, reducing triage time by 25% and associated costs by 84%. These results highlight StepCare’s value as a scalable, patient-centered solution for remote care during health crises. Full article

(This article belongs to the Proceedings of The 1st International Online Conference on Clinical Reports)

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15 pages, 3015 KiB

Open AccessProceeding Paper

Mapping Public Sentiment: A Data-Driven Analysis of COVID-19 Discourse on Social Media in Italy

by Gabriela Fernandez, Siddharth Suresh-Babu and Domenico Vito

Med. Sci. Forum 2025, 33(1), 3; https://doi.org/10.3390/msf2025033003 - 8 Jul 2025

Abstract

This study provides a detailed analysis of COVID-19-related social media discourse in Italy, using 535,886 tweets from 10 major cities between 30 August 2020 and 8 June 2021. The tweets were translated from Italian to English for analysis. A multifaceted methodology was employed: [...] Read more.

This study provides a detailed analysis of COVID-19-related social media discourse in Italy, using 535,886 tweets from 10 major cities between 30 August 2020 and 8 June 2021. The tweets were translated from Italian to English for analysis. A multifaceted methodology was employed: Latent Dirichlet Allocation (LDA) identified 20 key themes; sentiment analysis, using TextBlob, Flair, and TweetNLP, and emotion recognition using TweetNLP, revealed the emotional tone of the discourse, with 453 tweets unanimously positive across all algorithms. TextBlob was used for lexical analysis to rank the most salient positive and negative terms. The results indicated that positive sentiments centered on hope, safety measures, and vaccination progress, while negative sentiments focused on fear, death, and quarantine frustrations. This research offers valuable insights for public health officials, enabling tailored messaging, real-time strategy monitoring, and agile policymaking during the pandemic, with implications for future health crises. Full article

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7 pages, 813 KiB

Open AccessProceeding Paper

Molecular Docking Study of Natural Compounds Targeting the β2-Adrenergic Receptor (β2-AR)

by Sepideh Jafari and Joanna Bojarska

Med. Sci. Forum 2025, 34(1), 3; https://doi.org/10.3390/msf2025034003 - 8 Jul 2025

Abstract

G-protein-coupled receptors (GPCRs) are vital transmembrane proteins that regulate a wide range of physiological processes by transmitting extracellular signals into intracellular responses. Among them, the β2-adrenergic receptor (β2-AR) plays a central role in bronchodilation, smooth muscle relaxation, and cardiovascular modulation, making it a [...] Read more.

G-protein-coupled receptors (GPCRs) are vital transmembrane proteins that regulate a wide range of physiological processes by transmitting extracellular signals into intracellular responses. Among them, the β2-adrenergic receptor (β2-AR) plays a central role in bronchodilation, smooth muscle relaxation, and cardiovascular modulation, making it a key therapeutic target for diseases such as asthma, chronic obstructive pulmonary disease (COPD), and hypertension. This study explores the potential of natural bioactive compounds like ephedrine, quercetin, catechin, and resveratrol as alternative ligands for β2-AR through molecular docking analysis. Using AutoDock 4.6, these compounds were docked with the binding site of the β2-AR (PDB ID: 2RH1), and their binding affinities and interaction map were evaluated. Results showed that all compounds exhibited favorable binding energies and stable interactions with key receptor residues, with quercetin demonstrating the highest affinity. The findings suggest that these natural compounds may serve as promising leads for the development of safer, plant-derived modulators of β2-AR, supporting the role of computational approaches in natural product-based drug discovery. However, as docking cannot determine functional activity, these findings should be interpreted as preliminary and require experimental validation. Full article

(This article belongs to the Proceedings of The 3rd International Electronic Conference on Biomedicines)

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8 pages, 224 KiB

Open AccessProceeding Paper

Antimicrobial Resistance and Virulence in Escherichia coli from Broiler Production Unit: Genetic Insights for One Health

by Jessica Ribeiro, Vanessa Silva, Gilberto Igrejas, Sandrina A. Heleno, Filipa S. Reis and Patrícia Poeta

Med. Sci. Forum 2025, 35(1), 2; https://doi.org/10.3390/msf2025035002 - 7 Jul 2025

Abstract

The overuse of antibiotics in livestock contributes to antimicrobial resistance and zoonotic risk. This study investigated 19 Escherichia coli isolates from broiler feces (Savinor, Portugal), characterizing resistance genes, virulence factors, integrases, and phylogenetic groups by PCR. Most isolates carried ampC, tetA, [...] Read more.

The overuse of antibiotics in livestock contributes to antimicrobial resistance and zoonotic risk. This study investigated 19 Escherichia coli isolates from broiler feces (Savinor, Portugal), characterizing resistance genes, virulence factors, integrases, and phylogenetic groups by PCR. Most isolates carried ampC, tetA, blaCTX-M, and qnrS; all harbored fimA, and six had int1. Phylogroup A predominated. Resistance was mainly found in commensal groups, highlighting adaptation to poultry environments. The findings underscore the need for regional antimicrobial resistance monitoring and One Health strategies. Stewardship, biosecurity, and alternative measures are vital to mitigate antimicrobial resistance spread and zoonotic potential. Full article

(This article belongs to the Proceedings of The 4th International Electronic Conference on Antibiotics)

90 pages, 658 KiB

Open AccessConference Report

Abstracts of the 4th International Electronic Conference on Antibiotics

by Manuel Simões and Marc Maresca

Med. Sci. Forum 2025, 35(1), 1; https://doi.org/10.3390/msf2025035001 - 2 Jul 2025

Abstract

The 4th International Electronic Conference on Antibiotics (ECA2025) was an online conference held on 21–23 May 2025, organized by the MDPI journal Antibiotics. This event aims to bring together researchers and scholars to discuss a wide range of topics covering the aim [...] Read more.

The 4th International Electronic Conference on Antibiotics (ECA2025) was an online conference held on 21–23 May 2025, organized by the MDPI journal Antibiotics. This event aims to bring together researchers and scholars to discuss a wide range of topics covering the aim and scope of Antibiotics. We envision this conference as a highly interactive forum open to diverse interaction between its participants. It serves as a platform covering a broad range of topics, publishing papers on all aspects of antibiotics and encompassing the general fields of biochemistry, chemistry, genetics, microbiology, and pharmacology. Full article

(This article belongs to the Proceedings of The 4th International Electronic Conference on Antibiotics)

8 pages, 607 KiB

Open AccessProceeding Paper

Advancements in Nanotechnology for Orthopedic Applications: A Comprehensive Overview of Nanomaterials in Bone Tissue Engineering and Implant Innovation

by Newton Neogi, Kristi Priya Choudhury, Sabbir Hossain and Ibrahim Hossain

Med. Sci. Forum 2025, 32(1), 4; https://doi.org/10.3390/msf2025032004 - 26 Jun 2025

Abstract

Orthopedic implant technology has historically seen difficulties in attaining long-term stability and biological integration, leading to complications such as implant loosening, wear debris production, and heightened infection risk. Nanotechnology provides a revolutionary method for addressing these constraints through the introduction of materials characterized [...] Read more.

Orthopedic implant technology has historically seen difficulties in attaining long-term stability and biological integration, leading to complications such as implant loosening, wear debris production, and heightened infection risk. Nanotechnology provides a revolutionary method for addressing these constraints through the introduction of materials characterized by exceptional biocompatibility, durability, and integration potential. Nanomaterials (NMs), characterized by distinctive surface topographies and elevated surface area-to-volume ratios, facilitate improved osseointegration and provide regulated medication release, thereby creating a localized therapeutic milieu surrounding the implant site. To overcome the long-standing constraints of conventional implants, such as poor osseointegration, low mechanical fixation, immunological rejection, and implant-related infections, nanotechnology is causing a revolution in the field of orthopedic research. NMs are ideally suited for orthopedic applications due to their exceptional features, including increased tribology, wear resistance, prolonged drug administration, and excellent tissue regeneration. Because of their nanoscale size, they can imitate the hierarchical structure of real bone, which in turn encourages the proliferation of cells, lowers the risk of infection, and helps with the mending of bone fractures. This article will investigate the wide-ranging possibilities of nanostructured ceramics, polymers, metals, and carbon materials in bone tissue engineering, diagnostics, and the treatment of implant-related infections, bone malignancies, and bone healing. In addition, this paper will provide a basic overview of the most recent discoveries in nanotechnology driving the future of translational orthopedic research. It will also highlight safety evaluations and regulatory requirements for orthopedic devices. Full article

(This article belongs to the Proceedings of The 1st International Online Conference on Clinical Reports)

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8 pages, 2629 KiB

Open AccessProceeding Paper

Improving Bone Protection Provision for Patients with Fragility Fractures

by Aaron Goldberg

Med. Sci. Forum 2025, 32(1), 3; https://doi.org/10.3390/msf2025032003 - 20 Jun 2025

Abstract

Osteoporosis therapy is a crucial component of fragility fracture patients’ care. A Quality Improvement Project (QIP) was undertaken to review and improve such bone protection practice within a busy UK hospital orthopaedic department. Full-loop audit cycles, totalling 216 patients, were conducted before and [...] Read more.

Osteoporosis therapy is a crucial component of fragility fracture patients’ care. A Quality Improvement Project (QIP) was undertaken to review and improve such bone protection practice within a busy UK hospital orthopaedic department. Full-loop audit cycles, totalling 216 patients, were conducted before and after the implementation of a single-page checklist. This intervention significantly increased consultant-led osteoporosis plans by 37%, enhanced bone-sparing treatment administration by 20%, and eliminated unsafe prescriptions. Provision timeliness was not affected, but the communication of correct discharge information was significantly improved by 27%, and staff surveys showed the checklist was well-received, easy-to-use, and educational. Hopefully this will encourage other orthogeriatric teams to utilise a similarly effective and simple QI strategy. Full article

(This article belongs to the Proceedings of The 1st International Online Conference on Clinical Reports)

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6 pages, 570 KiB

Open AccessProceeding Paper

In Silico Evaluation of Diketopiperazine (DPK) Derivatives as Potential Inhibitors for G-Protein-Coupled Receptors (GPCRs)

by Sepideh Jafari and Joanna Bojarska

Med. Sci. Forum 2025, 34(1), 2; https://doi.org/10.3390/msf2025034002 - 19 Jun 2025

Abstract

G-protein-coupled receptors (GPCRs) are a group of various membrane proteins that mediate essential physiological processes by translating extracellular signals into intracellular responses. The β2-Adrenergic Receptor (β2-AR), a key GPCR, plays a critical role in smooth muscle relaxation, bronchodilation, and cardiovascular function, making it [...] Read more.

G-protein-coupled receptors (GPCRs) are a group of various membrane proteins that mediate essential physiological processes by translating extracellular signals into intracellular responses. The β2-Adrenergic Receptor (β2-AR), a key GPCR, plays a critical role in smooth muscle relaxation, bronchodilation, and cardiovascular function, making it an important therapeutic target for diseases such as asthma and hypertension. Diketopiperazines (DPKs), as cyclic peptides, have shown promise as scaffolds for inhibiting protein interactions and modulating receptor activity, offering a potential alternative to traditional small-molecule inhibitors with reduced side effects. In this study, five DPK derivatives were selected from the PubChem database and evaluated for their binding affinity to the 3D structure of β2-AR (PDB ID = 2RH1) through molecular docking studies using AutoDock 4.6 and MGLTools. The binding energy and hydrogen bond formation of each compound were evaluated to determine their interaction efficiency. Among the compounds, tryptophan-proline diketopiperazine (compound 3) exhibited the highest binding affinity with a binding energy of −5.89 kcal/mol. This enhanced interaction is attributed to the aromatic nature of tryptophan, which promotes strong π-π stacking interactions, and the rigidity of proline, which optimally fits within the receptor’s binding pocket. Hydrophobic interactions further stabilized the complex. These findings highlight compound 3 as a promising β2-AR modulator, providing valuable insights for the design of peptide-based inhibitors targeting β2-AR-related pathologies. Full article

(This article belongs to the Proceedings of The 3rd International Electronic Conference on Biomedicines)

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46 pages, 405 KiB

Open AccessConference Report

Abstracts of the 3rd International Electronic Conference on Biomedicines

by Felipe Fregni, Allan Stensballe, Georgia Levidou and Serafino Fazio

Med. Sci. Forum 2025, 34(1), 1; https://doi.org/10.3390/msf2025034001 - 13 Jun 2025

Abstract

The 3rd International Electronic Conference on Biomedicines (ECB 2025) was an online event held from 12 to 15 May 2025, by the journal Biomedicines MDPI. The goal of this conference was to enable scientists to present their latest research in the field of [...] Read more.

The 3rd International Electronic Conference on Biomedicines (ECB 2025) was an online event held from 12 to 15 May 2025, by the journal Biomedicines MDPI. The goal of this conference was to enable scientists to present their latest research in the field of biomedicines, especially on the discovery and characterization of new therapeutic targets in the era of precise medicine, and to engage in discussions with the scientific community worldwide. Recent advances in biomedical research have provided an advanced insight into the biological background of human disease, setting the groundwork for the development of new therapeutic strategies. The agenda of the conference included, but was not limited to, the following topics: insulin resistance or hyperinsulinemia; immunotherapy and adverse effects; the tumor microenvironment; the immune system, tumor immunology, and autoimmune disease; biomedicine in cardiovascular diseases; diabetes, obesity, and metabolic diseases; gene therapy and gene editing; rare diseases; and molecular mechanisms of neurodegeneration. Full article

(This article belongs to the Proceedings of The 3rd International Electronic Conference on Biomedicines)

17 pages, 1747 KiB

Open AccessProceeding Paper

Impact of Propensity Score-Adjusted Targeted Intervention on Survival Outcomes Among Patients with HIV: A Clinical Trial Analysis

by Ibrahim Abubakar Sadiq, Abubakar Usman, Jibril Yahaya Kajuru, Yahaya Zakari, Sani Ibrahim Doguwa, Idris Zubairu Sadiq and Aliyu Ismail Ishaq

Med. Sci. Forum 2025, 32(1), 2; https://doi.org/10.3390/msf2025032002 - 4 Jun 2025

Abstract

Background: This study investigates the survival outcomes of individuals with HIV receiving different treatment regimens compared to a control group. Utilizing a cohort dataset with demographic and clinical information, this research aims to assess the impact of various factors, including age, education, and [...] Read more.

Background: This study investigates the survival outcomes of individuals with HIV receiving different treatment regimens compared to a control group. Utilizing a cohort dataset with demographic and clinical information, this research aims to assess the impact of various factors, including age, education, and travel time, on survival while controlling for confounding effects using propensity score adjustment. Methods: A total of 380 patients with HIV were included in this study, categorized into an intervention group receiving a specific treatment regimen and a control group. The primary outcome measured was the time to death or censoring. Survival analysis was performed using the Cox proportional hazards model, adjusted for potential confounders, including treatment (intervention and control), age, education, travel time, and gestational age at enrollment. Propensity scores were also incorporated to adjust for treatment selection bias. Results: The Cox model revealed a significant protective effect of the intervention on survival (hazard ratio (HR) = 0.583, p = 0.045), indicating that the treatment improved survival outcomes compared to the control group. After adjusting for propensity scores, the relationship between the intervention and survival remained significant (HR = 0.631, p = 0.106), suggesting the robustness of the treatment’s effect even after accounting for confounding variables. Other covariates, such as age, education, and travel time, did not show significant independent effects on survival, likely due to their correlation with the treatment variable. Conclusions: This study highlights the crucial role of the intervention in enhancing survival among individuals with HIV. The use of propensity score adjustment improves the validity of these findings by mitigating confounding bias in observational data. These results highlight the importance of ART (antiretroviral therapy) in HIV management and demonstrate the utility of statistical methods like propensity scores in clinical research. Further studies with diverse populations and advanced methodologies are recommended to validate these findings across different settings. Full article

(This article belongs to the Proceedings of The 1st International Online Conference on Clinical Reports)

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12 pages, 1594 KiB

Open AccessProceeding Paper

The Association of the Global Climate Crisis with Environmental Risks and the Impact of Heat Stress on Occupational Safety, Health, and Hygiene

by Ioannis Adamopoulos, Niki Syrou, George Mpourazanis, Theodoros C. Constantinidis and George Dounias

Med. Sci. Forum 2025, 33(1), 2; https://doi.org/10.3390/msf2025033002 - 21 May 2025

Abstract

The relationship between the global climate crisis, which is associated with environmental risks, and occupational hygiene has not been extensively studied. This study develops a framework for identifying how climate change and the climate crisis could impact the workplace environment, workers, and occupational [...] Read more.

The relationship between the global climate crisis, which is associated with environmental risks, and occupational hygiene has not been extensively studied. This study develops a framework for identifying how climate change and the climate crisis could impact the workplace environment, workers, and occupational morbidity, mortality, and injury. A framework is used in this paper that is based on a review of the scientific literature published from 2014 to 2024, addressing climate risks, their interaction with occupational hazards, and their effects on the workforce. Eight categories of climate-related hazards are identified: increasingly high temperatures, dust and air pollution, sun and cosmic ultraviolet exposure, pandemics and infectious diseases, diseases transmitted by insects and changes in ecosystems, industrial occupational diseases, changes and crises in the built environment, and extreme weather events. Policies need to consider the gaps in the possibility of interactions between known hazards and new conditions and the productivity of workers, especially those who are most at risk of heat-related illnesses. Full article

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18 pages, 231 KiB

Open AccessConference Report

Abstracts of the 2nd International Electronic Conference on Vaccines (IECV 2024), 27–29 November 2024

by Sara Louise Cosby

Med. Sci. Forum 2025, 30(1), 1; https://doi.org/10.3390/msf2025030001 - 17 Apr 2025

Abstract

The 2nd International Electronic Conference on Vaccines (IECV 2024) took place online from 27 to 29 November 2024. This conference report is a collection of abstracts from six different sessions of IECV 2024. Full article

(This article belongs to the Proceedings of The 2nd International Electronic Conference on Vaccines)

14 pages, 1093 KiB

Open AccessProceeding Paper

Climate Change Risks and Impacts on Public Health Correlated with Air Pollution—African Dust in South Europe

by Ioannis Adamopoulos, Niki Syrou and Domenico Vito

Med. Sci. Forum 2025, 33(1), 1; https://doi.org/10.3390/msf2025033001 - 16 Apr 2025

Abstract

Climate change poses a significant risk to the environment and public health, leading to extreme weather patterns, rising sea levels, and loss of biodiversity. The relationship between air pollution from African dust and climate change demonstrates its critical role in trapping heat in [...] Read more.

Climate change poses a significant risk to the environment and public health, leading to extreme weather patterns, rising sea levels, and loss of biodiversity. The relationship between air pollution from African dust and climate change demonstrates its critical role in trapping heat in the atmosphere, resulting in heat-related illnesses, heart problems, and respiratory issues. This research points to the detrimental effects of pollutants such as smog, dust, acid rain, and ozone depletion on ecosystems, highlighting the importance of using geographically weighted regression modeling and the MODIS-NDVI analysis to address air pollution. Particulate Matter (PM_2.5–10) and ozone levels can have negative impacts on respiratory and cardiovascular health. Proactive steps, such as implementing clean energy technologies and enforcing stricter pollution regulations, are necessary to protect public health. Acting is crucial to addressing these global challenges and creating a cleaner, healthier future for future generations, underscoring the need for climate justice commitment. Full article

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31 pages, 311 KiB

Open AccessConference Report

Abstracts of 1st International Online Conference on Clinical Reports

by Toshio Hattori

Med. Sci. Forum 2025, 32(1), 1; https://doi.org/10.3390/msf2025032001 - 14 Apr 2025

Abstract

The 1st International Online Conference on Clinical Reports (IOCCR 2025) was held online on 19–20 March 2025, organized by the open access MDPI journal Reports (ISSN: 2571-841X; IF: 0.8). This conference offered a platform for doctors, experts, and medical-related practitioners in the field [...] Read more.

The 1st International Online Conference on Clinical Reports (IOCCR 2025) was held online on 19–20 March 2025, organized by the open access MDPI journal Reports (ISSN: 2571-841X; IF: 0.8). This conference offered a platform for doctors, experts, and medical-related practitioners in the field of medical cases, images, and videos in human medicine to engage in an exchange of ideas and share cutting-edge research findings. The conference encompassed diverse facets of clinical medicine, including, but not limited to, the following: Disaster/Climate Change Medicine, Cancer, Cardiovascular Diseases, Oral Diseases, and Orthopedic Surgery. Full article

(This article belongs to the Proceedings of The 1st International Online Conference on Clinical Reports)

249 pages, 12289 KiB

Open AccessConference Report

Abstracts from the 72nd Congress of the ESCVS, the European Society of CardioVascular and Endovascular Surgery

by Ergun Demirsoy and Matthias Thielmann

Med. Sci. Forum 2025, 31(1), 1; https://doi.org/10.3390/msf2025031001 - 3 Apr 2025

Abstract

The 72nd Annual International Congress of the European Society for Cardiovascular and Endovascular Surgery (ESCVS) 2024 in Istanbul, Turkey, marks a significant milestone in the advancement of cardiovascular surgery. As the main event in the cardiovascular surgery community calendar, this congress serves as [...] Read more.

The 72nd Annual International Congress of the European Society for Cardiovascular and Endovascular Surgery (ESCVS) 2024 in Istanbul, Turkey, marks a significant milestone in the advancement of cardiovascular surgery. As the main event in the cardiovascular surgery community calendar, this congress serves as a platform for leading experts, clinicians, and researchers to exchange information on the latest innovations, research results, and clinical procedures. This dedicated supplement to Proceedings provides a curated collection of abstracts presented at the congress, highlighting breakthrough contributions and fostering collaboration across the European and global cardiovascular surgery communities. The topics presented in this supplement represent a wide range of innovative advances in the fields of both cardiovascular and endovascular surgery. These include novel and minimally invasive surgical techniques, technological innovations, updates to clinical recommendations and guidelines, and new therapeutic strategies and procedures. Through the knowledge conveyed in these abstracts, the congress aims to advance the continuous evolution of patient care and outcomes in cardiac and vascular surgery. By showcasing the vibrant research and collaborative spirit of the ESCVS, this supplement provides valuable insights into the future directions of the field, emphasizing the importance of interdisciplinary approaches and innovation in addressing the complexities of cardiovascular disease. As cardiovascular care continues to evolve, the research and discussions presented at this congress will play a critical role in shaping the next generation of cardiac and vascular surgeons, promoting better patient outcomes, and improving the overall quality of cardiovascular health in Europe and worldwide. Full article

(This article belongs to the Proceedings of The 72nd International Congress of the European Society for CardioVascular and Endovascular Surgery)

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8 pages, 1287 KiB

Open AccessProceeding Paper

Modeling Electrical Potential in Multi-Dendritic Neurons Using Bessel Functions

by Kaouther Selmi, Souhaila Khalfallah and Kais Bouallegue

Med. Sci. Forum 2024, 28(1), 2; https://doi.org/10.3390/msf2024028002 - 20 Mar 2025

Cited by 1

Abstract

Understanding the distribution of electrical potential within neurons is critical for advancing our comprehension of neuronal signaling and communication. Neurons, the fundamental units of the nervous system, rely on complex electrochemical processes to transmit information. The intricate structure of neurons, especially those with [...] Read more.

Understanding the distribution of electrical potential within neurons is critical for advancing our comprehension of neuronal signaling and communication. Neurons, the fundamental units of the nervous system, rely on complex electrochemical processes to transmit information. The intricate structure of neurons, especially those with multiple dendrites, plays a crucial role in how these electrical signals are generated, propagated, and integrated. Despite significant progress in neuroscience, accurately modeling the electrical potential within neurons with elaborate dendritic architectures remains a challenge. This article introduces a novel approach to modeling the electrical potential in multi-dendritic neurons using Bessel functions, which offers a more precise and detailed representation of these processes. The proposed method involves solving the electric potential diffusion equation in cylindrical coordinates, a mathematical framework that naturally aligns with the geometry of dendrites. The radial and axial components of the solution are expressed using Bessel functions and sinusoidal functions, respectively. Bessel functions are particularly well-suited for this purpose due to their ability to describe waveforms in cylindrical systems, making them ideal for capturing the spatial variations in electrical potential within the cylindrical shape of dendrites. By leveraging this mathematical approach, we obtain a complete representation of the potential distribution across the neuron, from the soma (cell body) through the dendrites to the synaptic terminals. This model accurately captures the spatial variations of electrical potential in different regions of the neuron, including areas with complex dendritic arborizations, which are branching structures that significantly influence the neuron’s electrical characteristics. Simulation results underscore the effectiveness of this approach in reproducing realistic neuronal behavior. The model successfully mimics the way electrical signals propagate and interact within dendritic structures, providing crucial insights into the underlying mechanisms of signal integration and transmission in neurons. Full article

(This article belongs to the Proceedings of The 2nd International Electronic Conference on Clinical Medicine)

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21 pages, 1088 KiB

Open AccessConference Report

Eco-Friendly Antimicrobial Strategies to Fight Chronic Wound Infections Associated with Multidrug-Resistant Pathogens for the Development of Innovative Medical Systems (SCIAMI)

by Simonetta D’Ercole

Med. Sci. Forum 2025, 29(1), 1; https://doi.org/10.3390/msf2025029001 - 20 Mar 2025

Abstract

The SCIAMI International Workshop was held in Chieti, Italy, at University G. d’Annunzio, Chieti-Pescara, from 7 to 8 June 2024. It was organized by Simonetta D’Ercole and was funded by the European Union–Next Generation EU, “MUR-Fondo Promozione e Sviluppo–UdA, SCIAMI, Eco-friendly antimicrobial Strategies [...] Read more.

The SCIAMI International Workshop was held in Chieti, Italy, at University G. d’Annunzio, Chieti-Pescara, from 7 to 8 June 2024. It was organized by Simonetta D’Ercole and was funded by the European Union–Next Generation EU, “MUR-Fondo Promozione e Sviluppo–UdA, SCIAMI, Eco-friendly antimicrobial Strategies to fight Chronic wound Infections Associated with Multidrug resistant pathogens for the development of Innovative medical systems”. This conference report is an abstract collection from different sessions of SCIAMI. Full article

(This article belongs to the Proceedings of The 2024 SCIAMI International Workshop)

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1 pages, 137 KiB

Open AccessEditorial

Statement of Peer Review

by Margherita Ferrante and Gea Oliveri Conti

Med. Sci. Forum 2024, 25(1), 16; https://doi.org/10.3390/msf2024025016 - 24 Dec 2024

Abstract

In submitting conference proceedings to Medical Sciences Forum, the volume editors of the proceedings certify to the publisher that all papers published in this volume have been subjected to peer review administered by the volume editors [...] Full article

(This article belongs to the Proceedings of The 2nd International One Health Conference)

Journal Description

Medical Sciences Forum

Vol. 35

ECA 2025

Vol. 34

ECB 2025

Vol. 32

IOCCR 2025

Vol. 31

72nd ESCVS

Vol. 30

IECV 2024

Vol. 29

SCIAMI 2024

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