Paper Collection—Award Winning Papers in Biology and Life Sciences
We are pleased to announce that 74 papers in the field of Biology and Life Sciences have been selected as the 2025 Best Paper Award winners.
Agriculture:
Phosphorus-Solubilizing Microorganisms: A Key to Sustainable Agriculture
Silva, L.I.d.; Pereira, M.C.; Carvalho, A.M.X.d.; Buttrós, V.H.; Pasqual, M.; Dória, J.
Agriculture 2023, 13, 462. https://doi.org/10.3390/agriculture13020462
Microplastic Pollution in EU Farmland Soils: Preliminary Findings from Agricultural Soils (Southwestern Poland)
Medyńska-Juraszek, A.; Szczepańska, A.
Agriculture 2023, 13, 1733. https://doi.org/10.3390/agriculture13091733
Agronomy:
Agrivoltaics: The Environmental Impacts of Combining Food Crop Cultivation and Solar Energy Generation
Wagner, M.; Lask, J.; Kiesel, A.; Lewandowski, I.; Weselek, A.; Högy, P.; Trommsdorff, M.; Schnaiker, M.-A.; Bauerle, A.
Agronomy 2023, 13, 299. https://doi.org/10.3390/agronomy13020299
Integrating Agrivoltaic Systems into Local Industries: A Case Study and Economic Analysis of Rural Japan
Nakata, H.; Ogata, S.
Agronomy 2023, 13, 513. https://doi.org/10.3390/agronomy13020513
Improving Deep Learning Classifiers Performance via Preprocessing and Class Imbalance Approaches in a Plant Disease Detection Pipeline
Ojo, M.O.; Zahid, A.
Agronomy 2023, 13, 887. https://doi.org/10.3390/agronomy13030887
Applying IoT Sensors and Big Data to Improve Precision Crop Production: A Review
Alahmad, T.; Neményi, M.; Nyéki, A.
Agronomy 2023, 13, 2603. https://doi.org/10.3390/agronomy13102603
Animals:
Anyone Can Get Old—All You Have to Do Is Live Long Enough: Understanding Mortality and Life Expectancy in European Hedgehogs (Erinaceus europaeus)
Rasmussen, S.L.; Berg, T.B.; Martens, H.J.; Jones, O.R.
Animals 2023, 13, 626. https://doi.org/10.3390/ani13040626
Impact of Microplastics and Nanoplastics on Livestock Health: An Emerging Risk for Reproductive Efficiency
Urli, S.; Corte Pause, F.; Crociati, M.; Baufeld, A.; Monaci, M.; Stradaioli, G.
Animals 2023, 13, 1132. https://doi.org/10.3390/ani13071132
Effects of Long-Term Cold Stress on Growth Performance, Behavior, Physiological Parameters, and Energy Metabolism in Growing Beef Cattle
Wang, S.; Li, Q.; Peng, J.; Niu, H.
Animals 2023, 13, 1619. https://doi.org/10.3390/ani13101619
The Impact of Human Activities on Zoonotic Infection Transmissions
Esposito, M.M.; Turku, S.; Lehrfield, L.; Shoman, A.
Animals 2023, 13, 1646. https://doi.org/10.3390/ani13101646
Multiview Monitoring of Individual Cattle Behavior Based on Action Recognition in Closed Barns Using Deep Learning
Fuentes, A.; Han, S.; Nasir, M.F.; Park, J.; Yoon, S.; Park, D.S.
Animals 2023, 13, 2020. https://doi.org/10.3390/ani13122020
Antioxidants:
Antioxidants in Sunscreens: Which and What For?
Jesus, A.; Mota, S.; Torres, A.; Cruz, M.T.; Sousa, E.; Almeida, I.F.; Cidade, H.
Antioxidants 2023, 12, 138. https://doi.org/10.3390/antiox12010138
Antioxidant Activity as an Indicator of the Efficiency of Plant Extract-Mediated Synthesis of Zinc Oxide Nanoparticles
Vera, J.; Herrera, W.; Hermosilla, E.; Díaz, M.; Parada, J.; Seabra, A.B.; Tortella, G.; Pesenti, H.; Ciudad, G.; Rubilar, O.
Antioxidants 2023, 12, 784. https://doi.org/10.3390/antiox12040784
Potential of Plant Exosome Vesicles from Grapefruit (Citrus × paradisi) and Tomato (Solanum lycopersicum) Juices as Functional Ingredients and Targeted Drug Delivery Vehicles
Kilasoniya, A.; Garaeva, L.; Shtam, T.; Spitsyna, A.; Putevich, E.; Moreno-Chamba, B.; Salazar-Bermeo, J.; Komarova, E.; Malek, A.; Valero, M.; et al.
Antioxidants 2023, 12, 943. https://doi.org/10.3390/antiox12040943
The Applications and Mechanisms of Superoxide Dismutase in Medicine, Food, and Cosmetics
Zheng, M.; Liu, Y.; Zhang, G.; Yang, Z.; Xu, W.; Chen, Q.
Antioxidants 2023, 12, 1675. https://doi.org/10.3390/antiox12091675
Biology:
Predicting the Impact of Climate Change on the Habitat Distribution of Parthenium hysterophorus around the World and in South Korea
Adhikari, P.; Lee, Y.-H.; Poudel, A.; Lee, G.; Hong, S.-H.; Park, Y.-S.
Biology 2023, 12, 84. https://doi.org/10.3390/biology12010084
Geometric Morphometric Versus Genomic Patterns in a Large Polyploid Plant Species Complex
Hodač, L.; Karbstein, K.; Tomasello, S.; Wäldchen, J.; Bradican, J.P.; Hörandl, E.
Biology 2023, 12, 418. https://doi.org/10.3390/biology12030418
Mitochondria Quality Control and Male Fertility
Costa, J.; Braga, P.C.; Rebelo, I.; Oliveira, P.F.; Alves, M.G.
Biology 2023, 12, 827. https://doi.org/10.3390/biology12060827
Biomolecules:
Chronic Exposure to Low-Molecular-Weight Polycyclic Aromatic Hydrocarbons Promotes Lipid Accumulation and Metabolic Inflammation
Bright, A.; Li, F.; Movahed, M.; Shi, H.; Xue, B.
Biomolecules 2023, 13, 196. https://doi.org/10.3390/biom13020196
The Associations of Neutrophil–Lymphocyte, Platelet–Lymphocyte, Monocyte–Lymphocyte Ratios and Immune-Inflammation Index with Negative Symptoms in Patients with Schizophrenia
Šagud, M.; Madžarac, Z.; Nedic Erjavec, G.; Šimunović Filipčić, I.; Mikulić, F.L.; Rogić, D.; Bradaš, Z.; Bajs Janović, M.; Pivac, N.
Biomolecules 2023, 13, 297. https://doi.org/10.3390/biom13020297
Industrial Production of Proteins with Pichia pastoris—Komagataella phaffii
Barone, G.D.; Emmerstorfer-Augustin, A.; Biundo, A.; Pisano, I.; Coccetti, P.; Mapelli, V.; Camattari, A.
Biomolecules 2023, 13, 441. https://doi.org/10.3390/biom13030441
The Multifaceted Role of Glutathione S-Transferases in Health and Disease
Mazari, A.M.A.; Zhang, L.; Ye, Z.-W.; Zhang, J.; Tew, K.D.; Townsend, D.M.
Biomolecules 2023, 13, 688. https://doi.org/10.3390/biom13040688
Cells:
Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health
Mazziotta, C.; Tognon, M.; Martini, F.; Torreggiani, E.; Rotondo, J.C.
Cells 2023, 12, 184. https://doi.org/10.3390/cells12010184
Doxorubicin—An Agent with Multiple Mechanisms of Anticancer Activity
Kciuk, M.; Gielecińska, A.; Mujwar, S.; Kołat, D.; Kałuzińska-Kołat, Ż.; Celik, I.; Kontek, R.
Cells 2023, 12, 659. https://doi.org/10.3390/cells12040659
Gut-Microbiota-Derived Metabolites Maintain Gut and Systemic Immune Homeostasis
Wang, J.; Zhu, N.; Su, X.; Gao, Y.; Yang, R.
Cells 2023, 12, 793. https://doi.org/10.3390/cells12050793
Poly-L-Lactic Acid Fillers Improved Dermal Collagen Synthesis by Modulating M2 Macrophage Polarization in Aged Animal Skin
Oh, S.; Lee, J.H.; Kim, H.M.; Batsukh, S.; Sung, M.J.; Lim, T.H.; Lee, M.H.; Son, K.H.; Byun, K.
Cells 2023, 12, 1320. https://doi.org/10.3390/cells12091320
The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia
Glotfelty, E.J.; Tovar-y-Romo, L.B.; Hsueh, S.-C.; Tweedie, D.; Li, Y.; Harvey, B.K.; Hoffer, B.J.; Karlsson, T.E.; Olson, L.; Greig, N.H.
Cells 2023, 12, 1367. https://doi.org/10.3390/cells12101367
SIRT3 Deficiency Enhances Ferroptosis and Promotes Cardiac Fibrosis via p53 Acetylation
Su, H.; Cantrell, A.C.; Chen, J.-X.; Gu, W.; Zeng, H.
Cells 2023, 12, 1428. https://doi.org/10.3390/cells12101428
Current Issues in Molecular Biology:
Garlic (Allium sativum L.) as an Ally in the Treatment of Inflammatory Bowel Diseases
Zugaro, S.; Benedetti, E.; Caioni, G.
Curr. Issues Mol. Biol. 2023, 45, 685-698. https://doi.org/10.3390/cimb45010046
Lipid Peroxidation via Regulating the Metabolism of Docosahexaenoic Acid and Arachidonic Acid in Autistic Behavioral Symptoms
Yui, K.; Imataka, G.; Shiohama, T.
Curr. Issues Mol. Biol. 2023, 45, 9149-9164. https://doi.org/10.3390/cimb45110574
Fermentation:
Microbial Fermentation for Improving the Sensory, Nutritional and Functional Attributes of Legumes
Senanayake, D.; Torley, P.J.; Chandrapala, J.; Terefe, N.S.
Fermentation 2023, 9, 635. https://doi.org/10.3390/fermentation9070635
Effects of Temperature Shifts on Microbial Communities and Biogas Production: An In-Depth Comparison
Sudiartha, G.A.W.; Imai, T.; Mamimin, C.; Reungsang, A.
Fermentation 2023, 9, 642. https://doi.org/10.3390/fermentation9070642
Fishes:
Weight–Length Relationship Analysis Revealing the Impacts of Multiple Factors on Body Shape of Fish in China
Li, Y.; Feng, M.; Huang, L.; Zhang, P.; Wang, H.; Zhang, J.; Tian, Y.; Xu, J.
Fishes 2023, 8, 269. https://doi.org/10.3390/fishes8050269
A Comprehensive Review of the Impacts of Climate Change on Salmon: Strengths and Weaknesses of the Literature by Life Stage
Crozier, L.G.; Siegel, J.E.
Fishes 2023, 8, 319. https://doi.org/10.3390/fishes8060319
Foods:
Plant Protein versus Dairy Proteins: A pH-Dependency Investigation on Their Structure and Functional Properties
Tang, Q.; Roos, Y.H.; Miao, S.
Foods 2023, 12, 368. https://doi.org/10.3390/foods12020368
Effect of Edible Coating Enriched with Natural Antioxidant Extract and Bergamot Essential Oil on the Shelf Life of Strawberries
De Bruno, A.; Gattuso, A.; Ritorto, D.; Piscopo, A.; Poiana, M.
Foods 2023, 12, 488. https://doi.org/10.3390/foods12030488
Sustainable and Bio-Based Food Packaging: A Review on Past and Current Design Innovations
Versino, F.; Ortega, F.; Monroy, Y.; Rivero, S.; López, O.V.; García, M.A.
Foods 2023, 12, 1057. https://doi.org/10.3390/foods12051057
Biopolymer-Based Sustainable Food Packaging Materials: Challenges, Solutions, and Applications
Perera, K.Y.; Jaiswal, A.K.; Jaiswal, S.
Foods 2023, 12, 2422. https://doi.org/10.3390/foods12122422
Genes:
miRNAs: The Road from Bench to Bedside
Iacomino, G.
Genes 2023, 14, 314. https://doi.org/10.3390/genes14020314
Germline CNV Detection through Whole-Exome Sequencing (WES) Data Analysis Enhances Resolution of Rare Genetic Diseases
Tilemis, F.-N.; Marinakis, N.M.; Veltra, D.; Svingou, M.; Kekou, K.; Mitrakos, A.; Tzetis, M.; Kosma, K.; Makrythanasis, P.; Traeger-Synodinos, J.; et al.
Genes 2023, 14, 1490. https://doi.org/10.3390/genes14071490
Insects:
Global Distribution of Aedes aegypti and Aedes albopictus in a Climate Change Scenario of Regional Rivalry
Laporta, G.Z.; Potter, A.M.; Oliveira, J.F.A.; Bourke, B.P.; Pecor, D.B.; Linton, Y.-M.
Insects 2023, 14, 49. https://doi.org/10.3390/insects14010049
Dynamic Roles of Insect Carboxyl/Cholinesterases in Chemical Adaptation
Cruse, C.; Moural, T.W.; Zhu, F.
Insects 2023, 14, 194. https://doi.org/10.3390/insects14020194
Bioconversion of Different Waste Streams of Animal and Vegetal Origin and Manure by Black Soldier Fly Larvae Hermetia illucens L. (Diptera: Stratiomyidae)
Naser El Deen, S.; van Rozen, K.; Elissen, H.; van Wikselaar, P.; Fodor, I.; van der Weide, R.; Hoek-van den Hil, E.F.; Rezaei Far, A.; Veldkamp, T.
Insects 2023, 14, 204. https://doi.org/10.3390/insects14020204
Mosquito-Borne Diseases and Their Control Strategies: An Overview Focused on Green Synthesized Plant-Based Metallic Nanoparticles
Onen, H.; Luzala, M.M.; Kigozi, S.; Sikumbili, R.M.; Muanga, C.-J.K.; Zola, E.N.; Wendji, S.N.; Buya, A.B.; Balciunaitiene, A.; Viškelis, J.; et al.
Insects 2023, 14, 221. https://doi.org/10.3390/insects14030221
Isolation and Identification of Antioxidant Peptides Derived from Cricket (Gryllus bimaculatus) Protein Fractions
Fashakin, O.O.; Tangjaidee, P.; Unban, K.; Klangpetch, W.; Khumsap, T.; Sringarm, K.; Rawdkuen, S.; Phongthai, S.
Insects 2023, 14, 674. https://doi.org/10.3390/insects14080674
International Journal of Molecular Sciences:
Canagliflozin Attenuates Lipotoxicity in Cardiomyocytes by Inhibiting Inflammation and Ferroptosis through Activating AMPK Pathway
Zhang, W.; Lu, J.; Wang, Y.; Sun, P.; Gao, T.; Xu, N.; Zhang, Y.; Xie, W.
Int. J. Mol. Sci. 2023, 24, 858. https://doi.org/10.3390/ijms24010858
Neutrophil Extracellular Traps Promote Metastases of Colorectal Cancers through Activation of ERK Signaling by Releasing Neutrophil Elastase
Okamoto, M.; Mizuno, R.; Kawada, K.; Itatani, Y.; Kiyasu, Y.; Hanada, K.; Hirata, W.; Nishikawa, Y.; Masui, H.; Sugimoto, N.; et al.
Int. J. Mol. Sci. 2023, 24, 1118. https://doi.org/10.3390/ijms24021118
Pathophysiology of Inflammatory Bowel Disease: Innate Immune System
Saez, A.; Herrero-Fernandez, B.; Gomez-Bris, R.; Sánchez-Martinez, H.; Gonzalez-Granado, J.M.
Int. J. Mol. Sci. 2023, 24, 1526. https://doi.org/10.3390/ijms24021526
MUC1 Expression Affects the Immunoflogosis in Renal Cell Carcinoma Microenvironment through Complement System Activation and Immune Infiltrate Modulation
Lucarelli, G.; Netti, G.S.; Rutigliano, M.; Lasorsa, F.; Loizzo, D.; Milella, M.; Schirinzi, A.; Fontana, A.; Di Serio, F.; Tamma, R.; et al.
Int. J. Mol. Sci. 2023, 24, 4814. https://doi.org/10.3390/ijms24054814
Zinc: From Biological Functions to Therapeutic Potential
Costa, M.I.; Sarmento-Ribeiro, A.B.; Gonçalves, A.C.
Int. J. Mol. Sci. 2023, 24, 4822. https://doi.org/10.3390/ijms24054822
Tumor-Associated Macrophage Subsets: Shaping Polarization and Targeting
Zhang, Q.; Sioud, M.
Int. J. Mol. Sci. 2023, 24, 7493. https://doi.org/10.3390/ijms24087493
Life:
Bacteriostatic and Antibiofilm Efficacy of a Nisin Z Solution against Co-Cultures of Staphylococcus aureus and Pseudomonas aeruginosa from Diabetic Foot Infections
Serrano, I.; Alhinho, B.; Cunha, E.; Tavares, L.; Trindade, A.; Oliveira, M.
Life 2023, 13, 504. https://doi.org/10.3390/life13020504
Prebiotic Synthesis of Aspartate Using Life’s Metabolism as a Guide
Harrison, S.A.; Webb, W.L.; Rammu, H.; Lane, N.
Life 2023, 13, 1177. https://doi.org/10.3390/life13051177
Dermatophyte Infections Worldwide: Increase in Incidence and Associated Antifungal Resistance
Kruithoff, C.; Gamal, A.; McCormick, T.S.; Ghannoum, M.A.
Life 2024, 14, 1. https://doi.org/10.3390/life14010001
Metabolites:
Role of Oxidative Stress in Ocular Diseases: A Balancing Act
Shu, D.Y.; Chaudhary, S.; Cho, K.-S.; Lennikov, A.; Miller, W.P.; Thorn, D.C.; Yang, M.; McKay, T.B.
Metabolites 2023, 13, 187. https://doi.org/10.3390/metabo13020187
Optimization of Phenolic Compounds Extraction and Antioxidant Activity from Inonotus hispidus Using Ultrasound-Assisted Extraction Technology
Machado-Carvalho, L.; Martins, T.; Aires, A.; Marques, G.
Metabolites 2023, 13, 524. https://doi.org/10.3390/metabo13040524
Methods and Protocols:
Real-Time Monitoring of Lysosomal Membrane Permeabilization Using Acridine Orange
Eriksson, I.; Vainikka, L.; Persson, H.L.; Öllinger, K.
Methods Protoc. 2023, 6, 72. https://doi.org/10.3390/mps6040072
Microorganisms:
Sphingomonas sediminicola Is an Endosymbiotic Bacterium Able to Induce the Formation of Root Nodules in Pea (Pisum sativum L.) and to Enhance Plant Biomass Production
Mazoyon, C.; Hirel, B.; Pecourt, A.; Catterou, M.; Gutierrez, L.; Sarazin, V.; Dubois, F.; Duclercq, J.
Microorganisms 2023, 11, 199. https://doi.org/10.3390/microorganisms11010199
The Diversity of Escherichia coli Pathotypes and Vaccination Strategies against This Versatile Bacterial Pathogen
Pokharel, P.; Dhakal, S.; Dozois, C.M.
Microorganisms 2023, 11, 344. https://doi.org/10.3390/microorganisms11020344
Clostridioides difficile, a New “Superbug”
Markovska, R.; Dimitrov, G.; Gergova, R.; Boyanova, L.
Microorganisms 2023, 11, 845. https://doi.org/10.3390/microorganisms11040845
Antimicrobial Resistance in the Global Health Network: Known Unknowns and Challenges for Efficient Responses in the 21st Century
Coque, T.M.; Cantón, R.; Pérez-Cobas, A.E.; Fernández-de-Bobadilla, M.D.; Baquero, F.
Microorganisms 2023, 11, 1050. https://doi.org/10.3390/microorganisms11041050
Pathogens:
Zoonotic Mutation of Highly Pathogenic Avian Influenza H5N1 Virus Identified in the Brain of Multiple Wild Carnivore Species
Vreman, S.; Kik, M.; Germeraad, E.; Heutink, R.; Harders, F.; Spierenburg, M.; Engelsma, M.; Rijks, J.; van den Brand, J.; Beerens, N.
Pathogens 2023, 12, 168. https://doi.org/10.3390/pathogens12020168
HPV and Cervical Cancer: A Review of Epidemiology and Screening Uptake in the UK
Choi, S.; Ismail, A.; Pappas-Gogos, G.; Boussios, S.
Pathogens 2023, 12, 298. https://doi.org/10.3390/pathogens12020298
Prevalence, Resistance Patterns and Biofilm Production Ability of Bacterial Uropathogens from Cases of Community-Acquired Urinary Tract Infections in South Italy
Maione, A.; Galdiero, E.; Cirillo, L.; Gambino, E.; Gallo, M.A.; Sasso, F.P.; Petrillo, A.; Guida, M.; Galdiero, M.
Pathogens 2023, 12, 537. https://doi.org/10.3390/pathogens12040537
Recurrent Loss of Macrodomain Activity in Host Immunity and Viral Proteins
Delgado-Rodriguez, S.E.; Ryan, A.P.; Daugherty, M.D.
Pathogens 2023, 12, 674. https://doi.org/10.3390/pathogens12050674
Plants:
Multiplex CRISPR-Cas9 Gene-Editing Can Deliver Potato Cultivars with Reduced Browning and Acrylamide
Ly, D.N.P.; Iqbal, S.; Fosu-Nyarko, J.; Milroy, S.; Jones, M.G.K.
Plants 2023, 12, 379. https://doi.org/10.3390/plants12020379
Environmental Factors Regulate Plant Secondary Metabolites
Qaderi, M.M.; Martel, A.B.; Strugnell, C.A.
Plants 2023, 12, 447. https://doi.org/10.3390/plants12030447
Impacts of Radio-Frequency Electromagnetic Field (RF-EMF) on Lettuce (Lactuca sativa)—Evidence for RF-EMF Interference with Plant Stress Responses
Tran, N.T.; Jokic, L.; Keller, J.; Geier, J.U.; Kaldenhoff, R.
Plants 2023, 12, 1082. https://doi.org/10.3390/plants12051082
Melatonin-Mediated Enhancement of Photosynthetic Capacity and Photoprotection Improves Salt Tolerance in Wheat
Yan, D.; Wang, J.; Lu, Z.; Liu, R.; Hong, Y.; Su, B.; Wang, Y.; Peng, Z.; Yu, C.; Gao, Y.; et al.
Plants 2023, 12, 3984. https://doi.org/10.3390/plants12233984
Toxins:
Co-Occurrence of Mycotoxins in Feed for Cattle, Pigs, Poultry, and Sheep in Navarra, a Region of Northern Spain
Muñoz-Solano, B.; González-Peñas, E.
Toxins 2023, 15, 172. https://doi.org/10.3390/toxins15030172
Plant Toxic Proteins: Their Biological Activities, Mechanism of Action and Removal Strategies
Kocyigit, E.; Kocaadam-Bozkurt, B.; Bozkurt, O.; Ağagündüz, D.; Capasso, R.
Toxins 2023, 15, 356. https://doi.org/10.3390/toxins15060356
Ensemble Machine Learning of Gradient Boosting (XGBoost, LightGBM, CatBoost) and Attention-Based CNN-LSTM for Harmful Algal Blooms Forecasting
Ahn, J.M.; Kim, J.; Kim, K.
Toxins 2023, 15, 608. https://doi.org/10.3390/toxins15100608
Veterinary Sciences:
Antitumor Effects of Esculetin, a Natural Coumarin Derivative, against Canine Mammary Gland Tumor Cells by Inducing Cell Cycle Arrest and Apoptosis
Choi, J.; Yoo, M.-J.; Park, S.-Y.; Seol, J.-W.
Vet. Sci. 2023, 10, 84. https://doi.org/10.3390/vetsci10020084
Research Progress on the Development of Porcine Reproductive and Respiratory Syndrome Vaccines
Zhang, H.; Luo, Q.; He, Y.; Zheng, Y.; Sha, H.; Li, G.; Kong, W.; Liao, J.; Zhao, M.
Vet. Sci. 2023, 10, 491. https://doi.org/10.3390/vetsci10080491