Announcements

MDPI will attend the 29th Annual Meeting of Japan Society of Gene and Cell Therapy. This event will be held at the Osaka International Convention Center for three days from Monday, 11 September, to Wednesday, 13 September 2023.

The theme of this meeting is “Gene Therapy Making a Leap Forward – A Bridge to the Future through Cooperation between Industry, Government and Academia”. Gene and cell therapy has so far been centered on blood diseases, cancers, and metabolic disorders, but gene therapy for spinal muscular atrophy, an intractable neurological disease, was also launched in the US and Japan. Regulations must be well discussed with government agencies, PMDA, and other agencies. The Society will develop a meaningful program to enable sufficient discussions between stakeholders. In addition, a session will be organized by the Scientific Program Committee, a new committee established by the Japan Society of Gene and Cell Therapy.

The following MDPI journals will be represented:

• IJMS;
• CIMB;
• Antioxidants;
• Cancers;
• Current Oncology;
• Metabolites;
• SynBio;
• Biologics;
• Genes;
• Hemato.

If you plan on attending this conference, please feel free to stop by our booth and speak with us. Our delegates look forward to meeting you in person and answering any questions that you may have.

For more information about the conference, please visit https://www.c-linkage.co.jp/jsgct2023/en/index_en.html.

We are pleased to invite you to read the 2021 and 2022 selected papers in Cancers (ISSN: 2072-6694) on the topic of methods and technologies development. The paper list is as follows:

1. “Phenotypic Characterization by Mass Cytometry of the Microenvironment in Ovarian Cancer and Impact of Tumor Dissociation Methods”
by Shamundeeswari Anandan, Liv Cecilie V. Thomsen, Stein-Erik Gullaksen, Tamim Abdelaal, Katrin Kleinmanns, Jørn Skavland, Geir Bredholt, Bjørn Tore Gjertsen, Emmet McCormack and Line Bjørge
Cancers 2021, 13(4), 755; https://doi.org/10.3390/cancers13040755
Available online: https://www.mdpi.com/2072-6694/13/4/755

2. “3D Model Characterization by 2D and 3D Imaging in t(14;18)-Positive B-NHL: Perspectives for In Vitro Drug Screens in Follicular Lymphoma”
by Fabien Gava, Carla Faria, Pauline Gravelle, Juan G. Valero, Cèlia Dobaño-López, Renaud Morin, Marine Norlund, Aurélie Gomes, Jean-Michel Lagarde, Cédric Rossi et al.
Cancers 2021, 13(7), 1490; https://doi.org/10.3390/cancers13071490
Available online: https://www.mdpi.com/2072-6694/13/7/1490

3. “Magnetic Resonance Spectroscopy in Diagnosis and Follow-Up of Gliomas: State-of-the-Art”
by Malik Galijasevic, Ruth Steiger, Stephanie Mangesius, Julian Mangesius, Johannes Kerschbaumer,
Christian Franz Freyschlag, Nadja Gruber, Tanja Janjic, Elke Ruth Gizewski and Astrid Ellen Grams
Cancers 2022, 14(13), 3197; https://doi.org/10.3390/cancers14133197
Available online: https://www.mdpi.com/2072-6694/14/13/3197

4. “MEM: An Algorithm for the Reliable Detection of Microsatellite Instability (MSI) on a Small NGS Panel in Colorectal Cancer”
by Guillaume Herbreteau, Fabrice Airaud, Elise Pierre-Noël, Audrey Vallée, Stéphane Bézieau, Sandrine Théoleyre, Hélène Blons, Simon Garinet and Marc Guillaume Denis
Cancers 2021, 13(16), 4203; https://doi.org/10.3390/cancers13164203
Available online: https://www.mdpi.com/2072-6694/13/16/4203

5. “Distinct Cerebrovascular Reactivity Patterns for Brain Radiation Necrosis”
by Giovanni Muscas, Christiaan Hendrik Bas van Niftrik, Martina Sebök, Alessandro Della Puppa, Katharina Seystahl, Nicolaus Andratschke, Michelle Brown, Michael Weller, Luca Regli, Marco Piccirelli et al.
Cancers 2021, 13(8), 1840; https://doi.org/10.3390/cancers13081840
Available online: https://www.mdpi.com/2072-6694/13/8/1840

6. “Cell-Main Spectra Profile Screening Technique in Simulation of Circulating Tumour Cells Using MALDI-TOF Mass Spectrometry”
by Wararat Chiangjong, Sebastian Chakrit Bhakdi, Noppawan Woramongkolchai, Thitinee Vanichapol,
Nutkridta Pongsakul, Suradej Hongeng and Somchai Chutipongtanate
Cancers 2021, 13(15), 3775; https://doi.org/10.3390/cancers13153775
Available online: https://www.mdpi.com/2072-6694/13/15/3775

7. “Validation Study for Non-Invasive Prediction of IDH Mutation Status in Patients with Glioma Using In Vivo ¹H-Magnetic Resonance Spectroscopy and Machine Learning”
by Elisabeth Bumes, Claudia Fellner, Franz A. Fellner, Karin Fleischanderl, Martina Häckl, Stefan Lenz, Ralf Linker, Tim Mirus, Peter J. Oefner, Christian Paar et al.
Cancers 2022, 14(11), 2762; https://doi.org/10.3390/cancers14112762
Available online: https://www.mdpi.com/2072-6694/14/11/2762

8. “Diagnostic Performance of Ex Vivo Fluorescence Confocal Microscopy in the Assessment of Diagnostic Biopsies of the Prostate”
by Ulf Titze, Torsten Hansen, Christoph Brochhausen, Barbara Titze, Birte Schulz, Alfons Gunnemann,
Bernardo Rocco and Karl-Dietrich Sievert
Cancers 2021, 13(22), 5685; https://doi.org/10.3390/cancers13225685
Available online: https://www.mdpi.com/2072-6694/13/22/5685

9. “Experimental Validation of the MRcollar: An MR Compatible Applicator for Deep Heating in the Head and Neck Region”
by Kemal Sumser, Tomas Drizdal, Gennaro G. Bellizzi, Juan A. Hernandez-Tamames, Gerard C. van Rhoon and Margarethus Marius Paulides
Cancers 2021, 13(22), 5617; https://doi.org/10.3390/cancers13225617
Available online: https://www.mdpi.com/2072-6694/13/22/5617

10. “Inflammatory Microenvironment in Early Non-Small Cell Lung Cancer: Exploring the Predictive Value of Radiomics”
by Mariasole Perrone, Edoardo Raimondi, Matilde Costa, Gianluca Rasetto, Roberto Rizzati, Giovanni Lanza, Roberta Gafà, Giorgio Cavallesco, Nicola Tamburini, Pio Maniscalco et al.
Cancers 2022, 14(14), 3335; https://doi.org/10.3390/cancers14143335
Available online: https://www.mdpi.com/2072-6694/14/14/3335

11. “Unraveling the Structural Variations of Early-Stage Mycosis Fungoides—CD3 Based Purification and Third Generation Sequencing as Novel Tools for the Genomic Landscape in CTCL”
by Carsten Hain, Rudolf Stadler and Jörn Kalinowski
Cancers 2022, 14(18), 4466; https://doi.org/10.3390/cancers14184466
Available online: https://www.mdpi.com/2072-6694/14/18/4466

12. “Comparison of Structural and Short Variants Detected by Linked-Read and Whole-Exome Sequencing in Multiple Myeloma”
by Ashwini Kumar, Sadiksha Adhikari, Matti Kankainen and Caroline A. Heckman
Cancers 2021, 13(6), 1212; https://doi.org/10.3390/cancers13061212
Available online: https://www.mdpi.com/2072-6694/13/6/1212

13. “Tumour Size and T-Stage in Pancreatic Cancer Resection Specimens Depend on the Pathology Examination Approach”
by My Linh Tran, Maia Blomhoff Holm and Caroline Sophie Verbeke
Cancers 2022, 14(10), 2471; https://doi.org/10.3390/cancers14102471
Available online: https://www.mdpi.com/2072-6694/14/10/2471

14. “Biophysical Analysis of Acute and Late Toxicity of Radiotherapy in Gastric Marginal Zone Lymphoma—Impact of Radiation Dose and Planning Target Volume”
by Gabriele Reinartz, Andrea Baehr, Christopher Kittel, Michael Oertel, Uwe Haverkamp and Hans Th. Eich
Cancers 2021, 13(6), 1390; https://doi.org/10.3390/cancers13061390
Available online: https://www.mdpi.com/2072-6694/13/6/1390

15. “Updates on the Management of Acute Myeloid Leukemia”
by Sofía Huerga-Domínguez, Sara Villar, Felipe Prósper and Ana Alfonso-Piérola
Cancers 2022, 14(19), 4756; https://doi.org/10.3390/cancers14194756
Available online: https://www.mdpi.com/2072-6694/14/19/4756

You can check more information about the Section “Methods and Technologies Development” in Cancers at the following link: https://www.mdpi.com/journal/cancers/sections/Methods_Technologies_Development.

We are pleased to invite you to read the 2021 and 2022 selected papers in Cancers (ISSN: 2072-6694) on the topic of cancer biomarkers. The paper list is as follows:

1. “Liquid Biopsy in the Clinical Management of High-Grade Serous Epithelial Ovarian Cancer—Current Use and Future Opportunities”
by Lara Paracchini, Maurizio D’Incalci and Sergio Marchini
Cancers 2021, 13(10), 2386; https://doi.org/10.3390/cancers13102386
Available online: https://www.mdpi.com/2072-6694/13/10/2386

2. “Direct Regulation of DNA Repair by E2F and RB in Mammals and Plants: Core Function or Convergent Evolution?”
by Swarnalatha Manickavinayaham, Briana K. Dennehey and David G. Johnson
Cancers 2021, 13(5), 934; https://doi.org/10.3390/cancers13050934
Available online: https://www.mdpi.com/2072-6694/13/5/934

3. “From Immunohistochemistry to New Digital Ecosystems: A State-of-the-Art Biomarker Review for Precision Breast Cancer Medicine”
by Sean M. Hacking, Evgeny Yakirevich and Yihong Wang
Cancers 2022, 14(14), 3469; https://doi.org/10.3390/cancers14143469
Available online: https://www.mdpi.com/2072-6694/14/14/3469

4. “Role of MicroRNAs in the Development and Progression of the Four Medulloblastoma Subgroups”
by Emilia Bevacqua, Jasmin Farshchi, Maria Victoria Niklison-Chirou and Paola Tucci
Cancers 2021, 13(24), 6323; https://doi.org/10.3390/cancers13246323
Available online: https://www.mdpi.com/2072-6694/13/24/6323

5. “Gene Signatures Induced by Ionizing Radiation as Prognostic Tools in an In Vitro Experimental Breast Cancer Model”
by Gloria M. Calaf, Leodan A. Crispin, Debasish Roy, Francisco Aguayo, Juan P. Muñoz and Tammy C. Bleak
Cancers 2021, 13(18), 4571; https://doi.org/10.3390/cancers13184571
Available online: https://www.mdpi.com/2072-6694/13/18/4571

6. “Current Implications of microRNAs in Genome Stability and Stress Responses of Ovarian Cancer”
by Arkadiusz Gajek, Patrycja Gralewska, Agnieszka Marczak and Aneta Rogalska
Cancers 2021, 13(11), 2690; https://doi.org/10.3390/cancers13112690
Available online: https://www.mdpi.com/2072-6694/13/11/2690

7. “Rationale for Early Detection of EWSR1 Translocation-Associated Sarcoma Biomarkers in Liquid Biopsy”
by Felix I. L. Clanchy
Cancers 2021, 13(4), 824; https://doi.org/10.3390/cancers13040824
Available online: https://www.mdpi.com/2072-6694/13/4/824

8. “Bacterial-Viral Interactions in Human Orodigestive and Female Genital Tract Cancers: A Summary of Epidemiologic and Laboratory Evidence”
by Ikuko Kato, Jilei Zhang and Jun Sun
Cancers 2022, 14(2), 425; https://doi.org/10.3390/cancers14020425
Available online: https://www.mdpi.com/2072-6694/14/2/425

9. “Challenges for Better Diagnosis and Management of Pancreatic and Biliary Tract Cancers Focusing on Blood Biomarkers: A Systematic Review”
by Hiroto Tominaga, Juntaro Matsuzaki, Chihiro Oikawa, Kensho Toyoshima, Haruki Manabe, Eriko Ozawa, Atsushi Shimamura, Riko Yokoyama, Yusuke Serizawa, Takahiro Ochiya et al.
Cancers 2021, 13(16), 4220; https://doi.org/10.3390/cancers13164220
Available online: https://www.mdpi.com/2072-6694/13/16/4220

10. “Proteomics as a Complementary Technique to Characterize Bladder Cancer”
by Rubén López-Cortés, Sergio Vázquez-Estévez, Javier Álvarez Fernández and Cristina Núñez
Cancers 2021, 13(21), 5537; https://doi.org/10.3390/cancers13215537
Available online: https://www.mdpi.com/2072-6694/13/21/5537

11. “Genetic Alterations in Adult T-Cell Leukemia/Lymphoma: Novel Discoveries with Clinical and Biological Significance”
by Shugo Sakihama and Kennosuke Karube
Cancers 2022, 14(10), 2394; https://doi.org/10.3390/cancers14102394
Available online: https://www.mdpi.com/2072-6694/14/10/2394

12. “miRNA- and lncRNA-Based Therapeutics for Non-Hodgkin’s Lymphoma: Moving towards an RNA-Guided Precision Medicine”
by Mara Fernandes, Herlander Marques, Ana Luísa Teixeira and Rui Medeiros
Cancers 2021, 13(24), 6324; https://doi.org/10.3390/cancers13246324
Available online: https://www.mdpi.com/2072-6694/13/24/6324

13. “The Potential and Emerging Role of Quantitative Imaging Biomarkers for Cancer Characterization”
by Hishan Tharmaseelan, Alexander Hertel, Shereen Rennebaum, Dominik Nörenberg, Verena Haselmann, Stefan O. Schoenberg and Matthias F. Froelich
Cancers 2022, 14(14), 3349; https://doi.org/10.3390/cancers14143349
Available online: https://www.mdpi.com/2072-6694/14/14/3349

14. “A Clinical Update on the Prognostic Effect of microRNA Biomarkers for Survival Outcome in Nasopharyngeal Carcinoma: A Systematic Review and Meta-Analysis”
by Peter Shaw, Raghul Senthilnathan, Sunil Krishnan, Deepa Suresh, Sameep Shetty, Gothandam Kodiveri Muthukaliannan, Ravishankar Ram Mani, Palanisamy Sivanandy, Harish Chinna Konda Chandramoorthy, Madan Mohan Gupta et al.
Cancers 2021, 13(17), 4369; https://doi.org/10.3390/cancers13174369
Available online: https://www.mdpi.com/2072-6694/13/17/4369

15. “Familial Risk and Heritability of Hematologic Malignancies in the Nordic Twin Study of Cancer”
by Signe B. Clemmensen, Jennifer R. Harris, Jonas Mengel-From, Wagner H. Bonat, Henrik Frederiksen, Jaakko Kaprio and Jacob v. B. Hjelmborg
Cancers 2021, 13(12), 3023; https://doi.org/10.3390/cancers13123023
Available online: https://www.mdpi.com/2072-6694/13/12/3023

You can check more information about the Section “Cancer Biomarkers” in Cancers at the following link: https://www.mdpi.com/journal/cancers/sections/Cancer_Biomarkers.

We are pleased to invite you to read the 2021 and 2022 selected papers in Cancers (ISSN: 2072-6694) on the topic of molecular cancer biology. The paper list is as follows:

1. “Descriptive and Functional Genomics in Acute Myeloid Leukemia (AML): Paving the Road for a Cure”
by Hélène Pasquer, Maëlys Tostain, Nina Kaci, Blandine Roux and Lina Benajiba
Cancers 2021, 13(4), 748; https://doi.org/10.3390/cancers13040748
Available online: https://www.mdpi.com/2072-6694/13/4/748

2. “Tampering of Viruses and Bacteria with Host DNA Repair: Implications for Cellular Transformation”
by Francesca Benedetti, Sabrina Curreli, Robert C. Gallo and Davide Zella
Cancers 2021, 13(2), 241; https://doi.org/10.3390/cancers13020241
Available online: https://www.mdpi.com/2072-6694/13/2/241

3. “DNA Methylation and Intra-Clonal Heterogeneity: The Chronic Myeloid Leukemia Model”
by Benjamin Lebecque, Céline Bourgne, Véronique Vidal and Marc G. Berger
Cancers 2021, 13(14), 3587; https://doi.org/10.3390/cancers13143587
Available online: https://www.mdpi.com/2072-6694/13/14/3587

4. “Impact of Alternative Splicing Variants on Liver Cancer Biology”
by Jose J. G. Marin, Maria Reviejo, Meraris Soto, Elisa Lozano, Maitane Asensio, Sara Ortiz-Rivero, Carmen Berasain, Matias A. Avila and Elisa Herraez
Cancers 2022, 14(1), 18; https://doi.org/10.3390/cancers14010018
Available online: https://www.mdpi.com/2072-6694/14/1/18

5. “Genomic, Transcriptomic, and Functional Alterations in DNA Damage Response Pathways as Putative Biomarkers of Chemotherapy Response in Ovarian Cancer”
by Sweta Sharma Saha, Lucy Gentles, Alice Bradbury, Dominik Brecht, Rebecca Robinson, Rachel O’Donnell, Nicola J. Curtin and Yvette Drew
Cancers 2021, 13(6), 1420; https://doi.org/10.3390/cancers13061420
Available online: https://www.mdpi.com/2072-6694/13/6/1420

6. “NTRK1/TrkA Signaling in Neuroblastoma Cells Induces Nuclear Reorganization and Intra-Nuclear Aggregation of Lamin A/C”
by Lukas Funke, Thilo Bracht, Sebastian Oeck, Karin Schork, Markus Stepath, Sabine Dreesmann, Martin Eisenacher, Barbara Sitek and Alexander Schramm
Cancers 2021, 13(21), 5293; https://doi.org/10.3390/cancers13215293
Available online: https://www.mdpi.com/2072-6694/13/21/5293

7. “p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair?”
by Keane K. Y. Lai, Xiaohui Hu, Keisuke Chosa, Cu Nguyen, David P. Lin, Keith K. Lai, Nobuo Kato, Yusuke Higuchi, Sarah K. Highlander, Elizabeth Melendez et al.
Cancers 2021, 13(6), 1228; https://doi.org/10.3390/cancers13061288
Available online: https://www.mdpi.com/2072-6694/13/6/1288

8. “Exploring miRNA Signature and Other Potential Biomarkers for Oligometastatic Prostate Cancer Characterization: The Biological Challenge behind Clinical Practice. A Narrative Review”
by Giulia Corrao, Mattia Zaffaroni, Luca Bergamaschi, Matteo Augugliaro, Stefania Volpe, Matteo Pepa, Giuseppina Bonizzi, Salvatore Pece, Nicola Amodio, Francesco Alessandro Mistretta et al.
Cancers 2021, 13(13), 3278; https://doi.org/10.3390/cancers13133278
Available online: https://www.mdpi.com/2072-6694/13/13/3278

9. “The Cellular and Biological Impact of Extracellular Vesicles in Pancreatic Cancer”
by Zainab Hussain, Jeremy Nigri and Richard Tomasini
Cancers 2021, 13(12), 3040; https://doi.org/10.3390/cancers13123040
Available online: https://www.mdpi.com/2072-6694/13/12/3040

10. “The Role of Circular RNAs in Keratinocyte Carcinomas”
by Thomas Meyer, Michael Sand, Lutz Schmitz and Eggert Stockfleth
Cancers 2021, 13(16), 4240; https://doi.org/10.3390/cancers13164240
Available online: https://www.mdpi.com/2072-6694/13/16/4240

11. “MAPK Inhibition Requires Active RAC1 Signaling to Effectively Improve Iodide Uptake by Thyroid Follicular Cells”
by Márcia Faria, Rita Domingues, Maria João Bugalho, Paulo Matos and Ana Luísa Silva
Cancers 2021, 13(22), 5861; https://doi.org/10.3390/cancers13225861
Available online: https://www.mdpi.com/2072-6694/13/22/5861

12. “The Role of Fast-Cycling Atypical RHO GTPases in Cancer”
by Pontus Aspenström
Cancers 2022, 14(8), 1961; https://doi.org/10.3390/cancers14081961
Available online: https://www.mdpi.com/2072-6694/14/8/1961

13. “MicroRNA Profile Alterations in Parathyroid Carcinoma: Latest Updates and Perspectives”
by Marta Wielogórska, Beata Podgórska, Magdalena Niemira, Małgorzata Szelachowska, Adam Krętowski and Katarzyna Siewko
Cancers 2022, 14(4), 876; https://doi.org/10.3390/cancers14040876
Available online: https://www.mdpi.com/2072-6694/14/4/876

14. “MicroRNAs, Tristetraprolin Family Members and HuR: A Complex Interplay Controlling Cancer-Related Processes”
by Cyril Sobolewski, Laurent Dubuquoy and Noémie Legrand
Cancers 2022, 14(14), 3516; https://doi.org/10.3390/cancers14143516
Available online: https://www.mdpi.com/2072-6694/14/14/3516

15. “Analysis of Genomic Alterations Associated with Recurrence in Early Stage HER2-Positive Breast Cancer”
by Yong-Seok Kim, Der Sheng Sun, Juneyoung Ahn, Yongseon Kim, Jung-Sook Yoon and Hye Sung Won
Cancers 2022, 14(15), 3650; https://doi.org/10.3390/cancers14153650
Available online: https://www.mdpi.com/2072-6694/14/15/3650

You can check more information about the Section “Molecular Cancer Biology” in Cancers at the following link: https://www.mdpi.com/journal/cancers/sections/Molecular_Cancer_Biology.

We are pleased to invite you to read the 2021 and 2022 selected papers in Cancers (ISSN: 2072-6694) on the topic of cancer metastasis. The paper list is as follows:

1. “TP53 Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patient”
by Ritu Pandey, Nathan Johnson, Laurence Cooke, Benny Johnson, Yuliang Chen, Manjari Pandey, Jason Chandler and Daruka Mahadevan
Cancers 2021, 13(4), 597; https://doi.org/10.3390/cancers13040597
Available online: https://www.mdpi.com/2072-6694/13/4/597

2. “Perioperative Systemic Chemotherapy for Colorectal Liver Metastasis: Recent Updates”
by Hee Yeon Lee and In Sook Woo
Cancers 2021, 13(18), 4590; https://doi.org/10.3390/cancers13184590
Available online: https://www.mdpi.com/2072-6694/13/18/4590

3. “GPR87 Promotes Metastasis through the AKT-eNOS-NO Axis in Lung Adenocarcinoma”
by Hye-Mi Ahn, Eun-Young Choi and Youn-Jae Kim
Cancers 2022, 14(1), 19; https://doi.org/10.3390/cancers14010019
Available online: https://www.mdpi.com/2072-6694/14/1/19

4. “Machine Learning Model to Stratify the Risk of Lymph Node Metastasis for Early Gastric Cancer: A Single-Center Cohort Study”
by Ji-Eun Na, Yeong-Chan Lee, Tae-Jun Kim Hyuk Lee, Hong-Hee Won, Yang-Won Min, Byung-Hoon Min, Jun-Haeng Lee, Poong-Lyul Rhee and Jae J. Kim
Cancers 2022, 14(5), 1121; https://doi.org/10.3390/cancers14051121
Available online: https://www.mdpi.com/2072-6694/14/5/1121

5. “Salmonella Impacts Tumor-Induced Macrophage Polarization, and Inhibits SNAI1-Mediated Metastasis in Melanoma”
by Christian R. Pangilinan, Li-Hsien Wu and Che-Hsin Lee
Cancers 2021, 13(12), 2894; https://doi.org/10.3390/cancers13122894
Available online: https://www.mdpi.com/2072-6694/13/12/2894

6. “Immune Milieu Established by Postpartum Liver Involution Promotes Breast Cancer Liver Metastasis”
by Alexandra Q. Bartlett, Nathan D. Pennock, Alex Klug and Pepper Schedin
Cancers 2021, 13(7), 1698; https://doi.org/10.3390/cancers13071698
Available online: https://www.mdpi.com/2072-6694/13/7/1698

7. “HIF-Dependent CKB Expression Promotes Breast Cancer Metastasis, Whereas Cyclocreatine Therapy Impairs Cellular Invasion and Improves Chemotherapy Efficacy”
by Raisa I. Krutilina, Hilaire Playa, Danielle L. Brooks, Luciana P. Schwab, Deanna N. Parke, Damilola Oluwalana, Douglas R. Layman, Meiyun Fan, Daniel L. Johnson, Junming Yue et al.
Cancers 2022, 14(1), 27; https://doi.org/10.3390/cancers14010027
Available online: https://www.mdpi.com/2072-6694/14/1/27

8. “Canonical NF-κB Promotes Lung Epithelial Cell Tumour Growth by Downregulating the Metastasis Suppressor CD82 and Enhancing Epithelial-to-Mesenchymal Cell Transition”
by Eugenia Roupakia, Evangelia Chavdoula, Georgia Karpathiou, Giannis Vatsellas, Dimitrios Chatzopoulos, Angeliki Mela, Jennifer M. Gillette, Katharina Kriegsmann, Mark Kriegsmann, Anna Batistatou et al.
Cancers 2021, 13(17), 4302; https://doi.org/10.3390/cancers13174302
Available online: hhttps://www.mdpi.com/2072-6694/13/17/4302

9. “Inhibition of Liver Metastasis in Colorectal Cancer by Targeting IL-13/IL13Rα2 Binding Site with Specific Monoclonal Antibodies”
by Marta Jaén, Rubén A. Bartolomé, Carmen Aizpurua, Ángela Martin-Regalado, J. Ignacio Imbaud and J. Ignacio Casal
Cancers 2021, 13(7), 1731; https://doi.org/10.3390/cancers13071731
Available online: https://www.mdpi.com/2072-6694/13/7/1731

10. “A Highly Reliable Convolutional Neural Network Based Soft Tissue Sarcoma Metastasis Detection from Chest X-ray Images: A Retrospective Cohort Study”
by Christoph Wallner, Mansoor Alam, Marius Drysch, Johannes Maximilian Wagner, Alexander Sogorski, Mehran Dadras, Maxi von Glinski, Felix Reinkemeier, Mustafa Becerikli, Christoph Heute et al.
Cancers 2021, 13(19), 4961; https://doi.org/10.3390/cancers13194961
Available online: https://www.mdpi.com/2072-6694/13/19/4961

11. “SIPA1 Is a Modulator of HGF/MET Induced Tumour Metastasis via the Regulation of Tight Junction-Based Cell to Cell Barrier Function”
by Chang Liu, Wenguo Jiang, Lijian Zhang, Rachel Hargest and Tracey A. Martin
Cancers 2021, 13(7), 1747; https://doi.org/10.3390/cancers13071747
Available online: https://www.mdpi.com/2072-6694/13/7/1747

12. “Differential Expression of BOC, SPOCK2, and GJD3 Is Associated with Brain Metastasis of ER-Negative Breast Cancers”
by Rute M. S. M. Pedrosa, Leonoor V. Wismans, Renata Sinke, Marcel van der Weiden, Casper H. J. van Eijck, Johan M. Kros and Dana A. M. Mustafa
Cancers 2021, 13(12), 2982; https://doi.org/10.3390/cancers13122982
Available online: https://www.mdpi.com/2072-6694/13/12/2982

13. “Obesity-Activated Lung Stromal Cells Promote Myeloid Lineage Cell Accumulation and Breast Cancer Metastasis”
by Lauren E. Hillers-Ziemer, Abbey E. Williams, Amanda Janquart, Caitlin Grogan, Victoria Thompson, Adriana Sanchez and Lisa M. Arendt
Cancers 2021, 13(5), 1005; https://doi.org/10.3390/cancers13051005
Available online: https://www.mdpi.com/2072-6694/13/5/1005

14. “Salvage Nodal Radiotherapy as Metastasis-Directed Therapy for Oligorecurrent Prostate Cancer Detected by Positron Emission Tomography Shows Favorable Outcome in Long-Term Follow-Up”
by Jörg Tamihardja, Leonie Zehner, Philipp Hartrampf, Dominik Lisowski, Susanne Kneitz, Sinan Cirsi, Gary Razinskas, Michael Flentje and Bülent Pola
Cancers 2022, 14(15), 3766; https://doi.org/10.3390/cancers14153766
Available online: https://www.mdpi.com/2072-6694/14/15/3766

15. “Orai3 Regulates Pancreatic Cancer Metastasis by Encoding a Functional Store Operated Calcium Entry Channel”
by Samriddhi Arora, Jyoti Tanwar, Nutan Sharma, Suman Saurav and Rajender K. Motian
Cancers 2021, 13(23), 5937; https://doi.org/10.3390/cancers13235937
Available online: https://www.mdpi.com/2072-6694/13/23/5937

You can check more information about the Section “Cancer Metastasis” in Cancers at the following link: https://www.mdpi.com/journal/cancers/sections/Cancer_Metastasis.

We are pleased to invite you to read the 2021 and 2022 selected papers in Cancers (ISSN: 2072-6694) on the topic of clinical trials of cancer. The paper list is as follows:

1. “Comparative Efficacy and Safety of Programmed Death-1 Pathway Inhibitors in Advanced Gastroesophageal Cancers: A Systematic Review and Network Meta-analysis of Phase III Clinical Trials”
by Laercio Lopes da Silva, Pedro Nazareth Aguiar, Jr., Robin Park, Eduardo Edelman Saul, Benjamin Haaland and Gilberto de Lima Lopes
Cancers 2021, 13(11), 2614; https://doi.org/10.3390/cancers13112614
Available online: https://www.mdpi.com/2072-6694/13/11/2614

2. “The Current Landscape of Targeted Clinical Trials in Non-WNT/Non-SHH Medulloblastoma”
by David R. Ghasemi, Gudrun Fleischhack, Till Milde and Kristian W. Pajtler
Cancers 2022, 14(3), 679; https://doi.org/10.3390/cancers14030679
Available online: https://www.mdpi.com/2072-6694/14/3/679

3. “The Clinical and Pathological Profile of BRCA1 Gene Methylated Breast Cancer Women: A Meta-Analysis”
by Ilary Ruscito, Maria Luisa Gasparri, Maria Paola De Marco, Flavia Costanzi, Aris Raad Besharat, Andrea Papadia, Thorsten Kuehn, Oreste Davide Gentilini, Filippo Bellati and Donatella Caserta
Cancers 2021, 13(6), 1391; https://doi.org/10.3390/cancers13061391
Available online: https://www.mdpi.com/2072-6694/13/6/1391

4. “Potentially Curative Therapeutic Activity of NEO212, a Perillyl Alcohol-Temozolomide Conjugate, in Preclinical Cytarabine-Resistant Models of Acute Myeloid Leukemia”
by Axel H. Schönthal, Steve Swenson, Radu O. Minea, Hye Na Kim, Heeyeon Cho, Nazleen Mohseni, Yong-Mi Kim and Thomas C. Chen
Cancers 2021, 13(14), 3385; https://doi.org/10.3390/cancers13143385
Available online: https://www.mdpi.com/2072-6694/13/14/3385

5. “Development of Randomized Trials in Adults with Medulloblastoma—The Example of EORTC 1634-BTG/NOA-23”
by Peter Hau, Didier Frappaz, Elizabeth Hovey, Martin G. McCabe, Kristian W. Pajtler, Benedikt Wiestler, Clemens Seidel, Stephanie E. Combs, Linda Dirven, Martin Klein et al.
Cancers 2021, 13(14), 3451; https://doi.org/10.3390/cancers13143451
Available online: https://www.mdpi.com/2072-6694/13/14/3451

6. “Circulating Tumor Cells and Bevacizumab Pharmacokinetics during Neoadjuvant Treatment Combining Chemotherapy and Bevacizumab for Early Breast Cancer: Ancillary Analysis of the AVASTEM Trial”
by Renaud Sabatier, Jean-Yves Pierga, Hervé Curé, Rakan Abulnaja, Eric Lambaudie, François-Clément Bidard, Jean-Marc Extra, Patrick Sfumato and Anthony Gonçalves
Cancers 2021, 13(1), 140; https://doi.org/10.3390/cancers13010140
Available online: https://www.mdpi.com/2072-6694/13/1/140

7. “New Scenarios in Pharmacological Treatments of Head and Neck Squamous Cell Carcinomas”
by Cristina Porcheri and Thimios A. Mitsiadis
Cancers 2021, 13(21), 5515; https://doi.org/10.3390/cancers13215515
Available online: https://www.mdpi.com/2072-6694/13/21/5515

8. “A Phase II Study Demonstrates No Feasibility of Adjuvant Treatment with Six Cycles of S-1 and Oxaliplatin in Resectable Esophageal Adenocarcinoma, with ERCC1 as Biomarker for Response to SOX”
by Charlotte I. Stroes, Sandor Schokker, Remco J. Molenaar, Ron A. A. Mathôt, Maarten F. Bijlsma, Stephanie O. van der Woude, João P. Belo Pereira, Gerrit K. J. Hooijer, Rob H. A. Verhoeven, Annemieke Cats et al.
Cancers 2021, 13(4), 839; https://doi.org/10.3390/cancers13040839
Available online: https://www.mdpi.com/2072-6694/13/4/839

9. “Cardiovascular Toxicities Secondary to Biotherapy and Molecular Targeted Therapies in Neuroendocrine Neoplasms: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials”
by Charalampos Aktypis, Maria-Eleni Spei, Maria Yavropoulou, Göran Wallin, Anna Koumarianou, Gregory Kaltsas, Eva Kassi and Kosmas Daskalakis
Cancers 2021, 13(9), 2159; https://doi.org/10.3390/cancers13092159
Available online: https://www.mdpi.com/2072-6694/13/9/2159

10. “Dramatic Reduction of Distant Pancreatic Metastases Using Local Light Activation of Verteporfin with Nab-Paclitaxel”
by Michael Pigula, Zhiming Mai, Sriram Anbil, Myung-Gyu Choi, Kenneth Wang, Edward Maytin, Brian Pogue and Tayyaba Hasan
Cancers 2021, 13(22), 5781; https://doi.org/10.3390/cancers13225781
Available online: https://www.mdpi.com/2072-6694/13/22/5781

11. “Long-Term Treatment with Bortezomib Induces Specific Methylation Changes in Differentiated Neuronal Cells”
by Karolina Łuczkowska, Olga Taryma-Leśniak, Jan Bińkowski, Katarzyna E. Sokołowska, Dominik Strapagiel, Justyna Jarczak, Edyta Paczkowska, Bogusław Machaliński and Tomasz K. Wojdacz
Cancers 2022, 14(14), 3402; https://doi.org/10.3390/cancers14143402
Available online: https://www.mdpi.com/2072-6694/14/14/3402

12. “Efficacy and Synergy of Small Molecule Inhibitors Targeting FLT3-ITD+ Acute Myeloid Leukemia”
by Javier Bregante, Anna Schönbichler, Daniel Pölöske, Lina Degenfeld-Schonburg, Garazi Monzó Contreras, Emir Hadzijusufovic, Elvin D. de Araujo, Peter Valent, Richard Moriggl and Anna Orlova
Cancers 2021, 13(24), 6181; https://doi.org/10.3390/cancers13246181
Available online: https://www.mdpi.com/2072-6694/13/24/6181

13. “Oncogene-Induced Reprogramming in Acute Lymphoblastic Leukemia: Towards Targeted Therapy of Leukemia-Initiating Cells”
by Vincent Fregona, Manon Bayet and Bastien Gerby
Cancers 2021, 13(21), 5511; https://doi.org/10.3390/cancers13215511
Available online: https://www.mdpi.com/2072-6694/13/21/5511

14. “Adjuvant Treatment with Tyrosine Kinase Inhibitors in Epidermal Growth Factor Receptor Mutated Non-Small-Cell Lung Carcinoma Patients, Past, Present and Future”
by Walid Shalata, Binil Mathew Jacob and Abed Agbarya
Cancers 2021, 13(16), 4119; https://doi.org/10.3390/cancers13164119
Available online: https://www.mdpi.com/2072-6694/13/16/4119

15. “Molecular Targeted Therapies: Time for a Paradigm Shift in Medulloblastoma Treatment?”
by Lidia Gatto, Enrico Franceschi, Alicia Tosoni, Vincenzo Di Nunno, Stefania Bartolini and Alba Ariela Brandes
Cancers 2022, 14(2), 333; https://doi.org/10.3390/cancers14020333
Available online: https://www.mdpi.com/2072-6694/14/2/333

You can check more information about the Section “Clinical Trials of Cancer” in Cancers at the following link: https://www.mdpi.com/journal/cancers/sections/Clinical_Trials_Cancer.

To commemorate the World Hepatitis Day 2023, MDPI organized a webinar on 28 July 2023 to encourage researchers to come together, take action, and highlight how the exchange of findings facilitates efforts to raise awareness of hepatitis. The low coverage of testing and treatment is the most important gap to be addressed to achieve the global elimination goals of hepatitis B virus (HBV) by 2030.

Session 1:

 You can watch the recorded webinar below:

Session 2:

 You can watch the recorded webinar below:

 Relevant Special Issues:

Pathogens
“Research on Hepatitis B Virus: Past, Present, and Future”
Edited by: Hyung Joon Yim
Submission deadline: 31 August 2023 

JPM
“Novel Challenges and Therapeutic Options for Liver Diseases”
Edited by: Guido Gerken
Submission deadline: 30 September 2023 

Medicina
“Viral Hepatitis Research: Updates and Challenges”
Edited by: Endrit Shahini, Antonio Giovanni Solimando and Antonella Argentiero
Submission deadline: 15 October 2023 

Cells
“Non-alcoholic Steatohepatitis (NASH) and Liver Fibrosis: Molecular and Multicellular Control of Evolving Diseased States”
Edited by: Jérôme Eeckhoute
Submission deadline: 15 February 2024 

Diagnostics
“Diagnosis and Management of Liver Diseases—2nd Edition”
Edited by: Jeong-Ju Yoo
Submission deadline: 30 September 2023 

Vaccines
“Vaccination and Treatments against Viral Hepatitis: Achievements, Challenges and Perspectives”
Edited by: Bárbara Vieira Do Lago and Vinicius M. Mello
Submission deadline: 15 October 2023

We are pleased to invite you to read the 2021 and 2022 selected papers in Cancers (ISSN: 2072-6694) on the topic of cancer therapy. The paper list is as follows:

1. “CAR T-Cells for CNS Lymphoma: Driving into New Terrain?”
by Philipp Karschnia, Jens Blobner, Nico Teske, Florian Schöberl, Esther Fitzinger, Martin Dreyling, Joerg-Christian Tonn, Niklas Thon, Marion Subklewe and Louisa von Baumgarten
Cancers 2021, 13(10), 2503; https://doi.org/10.3390/cancers13102503
Available online: https://www.mdpi.com/2072-6694/13/10/2503

2. “Role of Chemotherapy in Vulvar Cancers: Time to Rethink Standard of Care?”
by Marco Mazzotta, Laura Pizzuti, Eriseld Krasniqi, Francesca Sofia Di Lisa, Federico Cappuzzo, Lorenza Landi, Domenico Sergi, Fabio Pelle, Sonia Cappelli, Claudio Botti et al.
Cancers 2021, 13(16), 4061; https://doi.org/10.3390/cancers13164061
Available online: https://www.mdpi.com/2072-6694/13/16/4061

3. “Current Knowledge about Mechanisms of Drug Resistance against ALK Inhibitors in Non-Small Cell Lung Cancer”
by Elisabeth Smolle, Valentin Taucher, Joerg Lindenmann, Philipp J. Jost and Martin Pichler
Cancers 2021, 13(4), 699; https://doi.org/10.3390/cancers13040699
Available online: https://www.mdpi.com/2072-6694/13/4/699

4. “Molecular Targeted Therapy in Myelodysplastic Syndromes: New Options for Tailored Treatments”
by Simona Pagliuca, Carmelo Gurnari and Valeria Visconte
Cancers 2022, 13(4), 784; https://doi.org/10.3390/cancers13040784
Available online: https://www.mdpi.com/2072-6694/13/4/784

5. “Targeting CX3CR1 Suppresses the Fanconi Anemia DNA Repair Pathway and Synergizes with Platinum”
by Jemina Lehto, Anna Huguet Ninou, Dimitrios Chioureas, Jos Jonkers and Nina M. S. Gustafsson
Cancers 2021, 13(6), 1442; https://doi.org/10.3390/cancers13061442
Available online: https://www.mdpi.com/2072-6694/13/6/1442

6. “The Agony of Choice—Where to Place the Wave of BCMA-Targeted Therapies in the Multiple Myeloma Treatment Puzzle in 2022 and Beyond”
by Irene Strassl, Martin Schreder, Normann Steiner, Jakob Rudzki, Hermine Agis, Tina Künz, Nino Müser, Wolfgang Willenbacher, Andreas Petzer, Peter Neumeister et al.
Cancers 2021, 13(18), 4701; https://doi.org/10.3390/cancers13184701
Available online: https://www.mdpi.com/2072-6694/13/18/4701

7. “Challenges of Neoantigen Targeting in Lynch Syndrome and Constitutional Mismatch Repair Deficiency Syndrome”
by Asima Abidi, Mark A. J. Gorris, Evan Brennan, Marjolijn C. J. Jongmans, Dilys D. Weijers, Roland P. Kuiper, Richarda M. de Voer, Nicoline Hoogerbrugge, Gerty Schreibelt and I. Jolanda M. de Vries
Cancers 2021, 13(10), 2345; https://doi.org/10.3390/cancers13102345
Available online: https://www.mdpi.com/2072-6694/13/10/2345

8. “Regulations, Open Data and Healthcare Innovation: A Case of MSK-IMPACT and Its Implications for Better Cancer Care”
by Takaharu Jibiki, Hayato Nishimura, Shintaro Sengoku and Kota Kodama
Cancers 2021, 13(14), 3448; https://doi.org/10.3390/cancers13143448
Available online: https://www.mdpi.com/2072-6694/13/14/3448

9. “Myelodysplastic Syndromes in the Postgenomic Era and Future Perspectives for Precision Medicine”
by Ioannis Chanias, Kristina Stojkov, Gregor Th. Stehle, Michael Daskalakis, Helena Simeunovic, Linet Muthoni Njue, Annatina S. Schnegg-Kaufmann, Naomi A. Porret, Ramanjaneyulu Allam, Tata Nageswara Rao et al.
Cancers 2021, 13(13), 3296; https://doi.org/10.3390/cancers13133296
Available online: https://www.mdpi.com/2072-6694/13/13/3296

10. “Prospective SPECT-CT Organ Dosimetry-Driven Radiation-Absorbed Dose Escalation Using the In-111 (¹¹¹In)/Yttrium 90 (⁹⁰Y) Ibritumomab Tiuxetan (Zevalin^®) Theranostic Pair in Patients with Lymphoma at Myeloablative Dose Levels”
by Richard L. Wahl, Eric C. Frey, Heather A. Jacene, Brad S. Kahl, Steven Piantadosi, Jesus A. Bianco, Richard J. Hammes, Miah Jung, Wayne Kasecamp, Bin He et al.
Cancers 2021, 13(11), 2828; https://doi.org/10.3390/cancers13112828
Available online: https://www.mdpi.com/2072-6694/13/11/2828

11. “Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease”
by Chaobo Chen, Hanghang Wu, Hui Ye, Agustín Tortajada, Sandra Rodríguez-Perales, Raúl Torres-Ruiz, August Vidal, Maria Isabel Peligros, Johanna Reissing, Tony Bruns et al.
Cancers 2022, 14(1), 78; https://doi.org/10.3390/cancers14010078
Available online: https://www.mdpi.com/2072-6694/14/1/78

12. “Challenges and Novel Opportunities of Radiation Therapy for Brain Metastases in Non-Small Cell Lung Cancer”
by Paola Anna Jablonska, Joaquim Bosch-Barrera, Diego Serrano, Manuel Valiente, Alfonso Calvo and Javier Aristu
Cancers 2021, 13(9), 2141; https://doi.org/10.3390/cancers13092141
Available online: https://www.mdpi.com/2072-6694/13/9/2141

13. “Quantification and Optimization of Standard-of-Care Therapy to Delay the Emergence of Resistant Bone Metastatic Prostate Cancer”
by Arturo Araujo, Leah M. Cook, Jeremy S. Frieling, Winston Tan, John A. Copland II, Manish Kohli, Shilpa Gupta, Jasreman Dhillon, Julio Pow-Sang, Conor C. Lynch et al.
Cancers 2021, 13(14), 677; https://doi.org/10.3390/cancers13040677
Available online: https://www.mdpi.com/2072-6694/13/4/677

14. “Gliomas Infiltrating the Corpus Callosum: A Systematic Review of the Literature”
by Paolo Palmisciano, Gianluca Ferini, Gina Watanabe, Christian Ogasawara, Emal Lesha, Othman Bin-Alamer, Giuseppe E. Umana, Kenny Yu, Aaron A. Cohen-Gadol, Tarek Y. El Ahmadieh et al.
Cancers 2022, 14(10), 2507; https://doi.org/10.3390/cancers14102507
Available online: https://www.mdpi.com/2072-6694/14/10/2507

15. “Defining the Criteria for Reflex Testing for BRAF Mutations in Cutaneous Melanoma Patients”
by Sarah Zhou, Daniel Sikorski, Honghao Xu, Andrei Zubarev, May Chergui, François Lagacé, Wilson H. Miller, Jr., Margaret Redpath, Stephanie Ghazal, Marcus O. Butler et al.
Cancers 2021, 13(9), 2282; https://doi.org/10.3390/cancers13092282
Available online: https://www.mdpi.com/2072-6694/13/9/2282

You can check more information about the Section “Cancer Therapy” in Cancers at the following link: https://www.mdpi.com/journal/cancers/sections/Cancer_Therapy.

We are pleased to invite you to read the 2021 and 2022 selected papers in Cancers (ISSN: 2072-6694) in the Section “Cancer Informatics and Big Data”. The paper list is as follows:

1. “The Transcriptomic Landscape of Prostate Cancer Development and Progression: An Integrative Analysis”
by Jacek Marzec, Helen Ross-Adams, Stefano Pirrò, Jun Wang, Yanan Zhu, Xueying Mao, Emanuela Gadaleta, Amar S. Ahmad, Bernard V. North, Solène-Florence Kammerer-Jacquet et al.
Cancers 2021, 13(2), 345; https://doi.org/10.3390/cancers13020345
Available online: https://www.mdpi.com/2072-6694/13/2/345

2. “Bioinformatic Approaches to Validation and Functional Analysis of 3D Lung Cancer Models”
by P. Jonathan Li, Jeroen P. Roose, David M. Jablons and Johannes R. Kratz
Cancers 2021, 13(4), 701; https://doi.org/10.3390/cancers13040701
Available online: https://www.mdpi.com/2072-6694/13/4/701

3. “Cancers in Agreement? Exploring the Cross-Talk of Cancer Metabolomic and Transcriptomic Landscapes Using Publicly Available Data”
by Derek van Tilborg and Edoardo Saccenti
Cancers 2021, 13(3), 393; https://doi.org/10.3390/cancers13030393
Available online: https://www.mdpi.com/2072-6694/13/3/393

4. “Comprehensively Exploring the Mutational Landscape and Patterns of Genomic Evolution in Hypermutated Cancers”
by Peng-Chan Lin, Yu-Min Yeh, Hui-Ping Hsu, Ren-Hao Chan, Bo-Wen Lin, Po-Chuan Chen, Chien-Chang Pan, Keng-Fu Hsu, Jenn-Ren Hsiao, Yan-Shen Shan et al.
Cancers 2021, 13(17), 4317; https://doi.org/10.3390/cancers13174317
Available online: https://www.mdpi.com/2072-6694/13/17/4317

5. “Epigenomic Analysis of RAD51 ChIP-seq Data Reveals cis-regulatory Elements Associated with Autophagy in Cancer Cell Lines”
by Keunsoo Kang, Yoonjung Choi, Hyeonjin Moon, Chaelin You, Minjin Seo, Geunho Kwon, Jahyun Yun, Boram Beck and Kyuho Kang
Cancers 2021, 13(11), 2547; https://doi.org/10.3390/cancers13112547
Available online: https://www.mdpi.com/2072-6694/13/11/2547

6. “Identifying Cancer Drivers Using DRIVE: A Feature-Based Machine Learning Model for a Pan-Cancer Assessment of Somatic Missense Mutations”
by Ionut Dragomir, Adnan Akbar, John W. Cassidy, Nirmesh Patel, Harry W. Clifford and Gianmarco Contino
Cancers 2021, 13(11), 2779; https://doi.org/10.3390/cancers13112779
Available online: https://www.mdpi.com/2072-6694/13/11/2779

7. “SurvCNN: A Discrete Time-to-Event Cancer Survival Estimation Framework Using Image Representations of Omics Data”
by Yogesh Kalakoti, Shashank Yadav and Durai Sundar
Cancers 2021, 13(13), 3106; https://doi.org/10.3390/cancers13133106
Available online: https://www.mdpi.com/2072-6694/13/13/3106

8. “Gene-Mutation-Based Algorithm for Prediction of Treatment Response in Colorectal Cancer Patients”
by Heather Johnson, Zahra El-Schich, Amjad Ali, Xuhui Zhang, Athanasios Simoulis, Anette Gjörloff Wingren and Jenny L. Persson
Cancers 2022, 14(8), 2045; https://doi.org/10.3390/cancers14082045
Available online: https://www.mdpi.com/2072-6694/14/8/2045

9. “Discovering Digital Tumor Signatures—Using Latent Code Representations to Manipulate and Classify Liver Lesions”
by Jens Kleesiek, Benedikt Kersjes, Kai Ueltzhöffer, Jacob M. Murray, Carsten Rother, Ullrich Köthe and Heinz-Peter Schlemmer
Cancers 2021, 13(13), 3108; https://doi.org/10.3390/cancers13133108
Available online: https://www.mdpi.com/2072-6694/13/13/3108

10. “Predicting Postoperative Complications in Cancer Patients: A Survey Bridging Classical and Machine Learning Contributions to Postsurgical Risk Analysis”
by Gonçalves, Daniel M., Rui Henriques and Rafael S. Costa
Cancers 2021, 13(13), 3217; https://doi.org/10.3390/cancers13133217
Available online: https://www.mdpi.com/2072-6694/13/13/3217

11. “Survival-Critical Genes Associated with Copy Number Alterations in Lung Adenocarcinoma”
by Chinthalapally V. Rao, Chao Xu, Mudassir Farooqui, Yuting Zhang, Adam S. Asch and Hiroshi Y. Yamada
Cancers 2021, 13(11), 2586; https://doi.org/10.3390/cancers13112586
Available online: https://www.mdpi.com/2072-6694/13/11/2586

12. “PPAR-Responsive Elements Enriched with Alu Repeats May Contribute to Distinctive PPARγ–DNMT1 Interactions in the Genome”
by Sharma Amit, Fabian Tobar-Tosse, Tikam Chand Dakal, Hongde Liu, Arijit Biswas, Athira Menon, Anoosha Paruchuri, Panagiotis Katsonis, Olivier Lichtarge, M. Michael Gromiha et al.
Cancers 2021, 13(16), 3993; https://doi.org/10.3390/cancers13163993
Available online: https://www.mdpi.com/2072-6694/13/16/3993

13. “Network-Based Analysis to Identify Drivers of Metastatic Prostate Cancer Using GoNetic”
by Louise de Schaetzen van Brienen, Giles Miclotte, Maarten Larmuseau, Jimmy Van den Eynden and Kathleen Marchal
Cancers 2021, 13(21), 5291; https://doi.org/10.3390/cancers13215291
Available online: https://www.mdpi.com/2072-6694/13/21/5291

14. “Network-Based Integration of Multi-Omics Data Identifies the Determinants of miR-491-5p Effects”
by Matthieu Meryet-Figuiere, Mégane Vernon, Mamy Andrianteranagna, Bernard Lambert, Célia Brochen, Jean-Paul Issartel, Audrey Guttin, Pascal Gauduchon, Emilie Brotin, Florent Dingli et al.
Cancers 2021, 13(16), 3970; https://doi.org/10.3390/cancers13163970
Available online: https://www.mdpi.com/2072-6694/13/16/3970

15. “Prediction of Incident Cancers in the Lifelines Population-Based Cohort”
by Francisco O. Cortés-Ibañez, Sunil Belur Nagaraj, Ludo Cornelissen, Gerjan J. Navis, Bert van der Vegt, Grigory Sidorenkov and Geertruida H. de Bock
Cancers 2021, 13(9), 2133; https://doi.org/10.3390/cancers13092133
Available online: https://www.mdpi.com/2072-6694/13/9/2133

You can check more information about the Section “Cancer Informatics and Big Data” in Cancers at the following link: https://www.mdpi.com/journal/cancers/sections/Cancer_Informatics_Big_Data.

We are pleased to invite you to read the 2021 and 2022 selected papers in Cancers (ISSN: 2072-6694) on the topic of cancer pathophysiology. The paper list is as follows:

1. “The Prevalence of TET2 Gene Mutations in Patients with BCR-ABL-Negative Myeloproliferative Neoplasms (MPN): A Systematic Review and Meta-Analysis”
by Yuh Cai Chia, Md Asiful Islam, Phil Hider, Peng Yeong Woon, Muhammad Farid Johan, Rosline Hassan and Marini Ramli
Cancers 2021, 13(12), 3078; https://doi.org/10.3390/cancers13123078
Available online: https://www.mdpi.com/2072-6694/13/12/3078

2. “Recent Advances in Implantation-Based Genetic Modeling of Biliary Carcinogenesis in Mice”
by Masashi Izumiya, Shingo Kato and Yoshitaka Hippo
Cancers 2021, 13(10), 2292; https://doi.org/10.3390/cancers13102292
Available online: https://www.mdpi.com/2072-6694/13/10/2292

3. “ECM Remodeling in Squamous Cell Carcinoma of the Aerodigestive Tract: Pathways for Cancer Dissemination and Emerging Biomarkers”
by Albina Fejza, Lucrezia Camicia, Evelina Poletto, Greta Carobolante, Maurizio Mongiat and Eva Andreuzzi
Cancers 2021, 13(11), 2759; https://doi.org/10.3390/cancers13112759
Available online: https://www.mdpi.com/2072-6694/13/11/2759

4. “Pathological Changes in Pancreatic Carcinogenesis: A Review”
by Keiko Yamakawa, Juanjuan Ye, Yuko Nakano-Narusawa and Yoko Matsuda
Cancers 2021, 13(4), 686; https://doi.org/10.3390/cancers13040686
Available online: https://www.mdpi.com/2072-6694/13/4/686

5. “Phosphodiesterase 4D Depletion/Inhibition Exerts Anti-Oncogenic Properties in Hepatocellular Carcinoma”
by Federica Ragusa, Nadia Panera, Silvia Cardarelli, Marco Scarsella, Marzia Bianchi, Stefano Biagioni, Mauro Giorgi, Anna Alisi and Mara Massimi
Cancers 2021, 13(9), 2182; https://doi.org/10.3390/cancers13092182
Available online: https://www.mdpi.com/2072-6694/13/9/2182

6. “Molecular and Clinical Implications of Somatostatin Receptor Profile and Somatostatin Analogues Treatment in Oral Cavity Squamous Cell Carcinoma”
by Alba Sanjuan-Sanjuan, Emilia Alors-Perez, Marina Sanchez-Frías, Alicia Dean-Ferrer, Manuel D. Gahete, Susana Heredero-Jung and Raúl M. Luque
Cancers 2021, 13(19), 4828; https://doi.org/10.3390/cancers13194828
Available online: https://www.mdpi.com/2072-6694/13/19/4828

7. “Familial Occurrence of Adult Granulosa Cell Tumors: Analysis of Whole-Genome Germline Variants”
by Joline F. Roze, Joachim Kutzera, Wouter Koole, Margreet G. E. M. Ausems, Kristi Engelstad, Jurgen M. J. Piek, Cor D. de Kroon, René H. M. Verheijen, Gijs van Haaften, Ronald P. Zweemer et al.
Cancers 2021, 13(10), 2430; https://doi.org/10.3390/cancers13102430
Available online: https://www.mdpi.com/2072-6694/13/10/2430

8. “Prognostic Value of Apoptosis-Inducing Factor (AIF) in Germ Cell Tumors”
by Katarina Letkovska, Pavel Babal, Zuzana Cierna, Silvia Schmidtova, Veronika Liskova, Katarína Kalavska, Vera Miskovska, Samuel Horak, Katarina Rejlekova, Michal Chovanec et al.
Cancers 2021, 13(4), 776; https://doi.org/10.3390/cancers13040776
Available online: https://www.mdpi.com/2072-6694/13/4/776

9. “Bone Marrow Homeostasis Is Impaired via JAK/STAT and Glucocorticoid Signaling in Cancer Cachexia Model”
by Jinyeong Yu, Sanghyuk Choi, Aran Park, Jungbeom Do, Donghyun Nam, Youngjae Kim, Jinok Noh, Kil Yeon Lee, Chi Hoon Maeng and Ki-Sook Park
Cancers 2021, 13(5), 1059; https://doi.org/10.3390/cancers13051059
Available online: https://www.mdpi.com/2072-6694/13/5/1059

10. “Multiple Myeloma Relapse Is Associated with Increased NFκB Pathway Activity and Upregulation of the Pro-Survival BCL-2 Protein BFL-1”
by Ingrid Spaan, Anja van de Stolpe, Reinier A. Raymakers and Victor Peperzak
Cancers 2021, 13(18), 4668; https://doi.org/10.3390/cancers13184668
Available online: https://www.mdpi.com/2072-6694/13/18/4668

11. “APOBEC SBS13 Mutational Signature—A Novel Predictor of Radioactive Iodine Refractory Papillary Thyroid Carcinoma”
by Sarah Siraj, Tariq Masoodi, Abdul K. Siraj, Saud Azam, Zeeshan Qadri, Sandeep K. Parvathareddy, Rong Bu, Khawar S. Siddiqui, Saif S. Al-Sobhi, Mohammed AlDawish et al.
Cancers 2022, 14(6), 1584; https://doi.org/10.3390/cancers14061584
Available online: https://www.mdpi.com/2072-6694/14/6/1584

12. “Glioblastomas within the Subventricular Zone Are Region-Specific Enriched for Mesenchymal Transition Markers: An Intratumoral Gene Expression Analysis”
by Diana J. Z. Dalemans, Sharon Berendsen, Kaspar Draaisma, Pierre A. Robe and Tom J. Snijders
Cancers 2021, 13(15), 3764; https://doi.org/10.3390/cancers13153764
Available online: https://www.mdpi.com/2072-6694/13/15/3764

13. “Investigating the Interplay between Myeloma Cells and Bone Marrow Stromal Cells in the Development of Drug Resistance: Dissecting the Role of Epigenetic Modifications”
by Jacqueline Schütt, Theresa Nägler, Tino Schenk and Annamaria Brioli
Cancers 2021, 13(16), 4069; https://doi.org/10.3390/cancers13164069
Available online: https://www.mdpi.com/2072-6694/13/16/4069

14. “MiRNA Deregulation Distinguishes Anaplastic Thyroid Carcinoma (ATC) and Supports Upregulation of Oncogene Expression”
by Danny Misiak, Marcus Bauer, Jana Lange, Jacob Haase, Juliane Braun, Kerstin Lorenz, Claudia Wickenhauser and Stefan Hüttelmaier
Cancers 2021, 13(23), 5913; https://doi.org/10.3390/cancers13235913
Available online: https://www.mdpi.com/2072-6694/13/23/5913

15. “Loss of MAGEC3 Expression Is Associated with Prognosis in Advanced Ovarian Cancers”
by James Ellegate, Jr., Michalis Mastri, Emily Isenhart, John J. Krolewski, Gurkamal Chatta, Eric Kauffman, Melissa Moffitt and Kevin H. Eng
Cancers 2022, 14(3), 731; https://doi.org/10.3390/cancers14030731
Available online: https://www.mdpi.com/2072-6694/14/3/731

You can check more information about the Section “Cancer Pathophysiology” in Cancers at the following link: https://www.mdpi.com/journal/cancers/sections/Cancer_Pathophysiology.