Gene Signatures Induced by Ionizing Radiation as Prognostic Tools in an In Vitro Experimental Breast Cancer Model
Abstract
:Simple Summary
Abstract
1. Introduction
2. Radiation Overview
3. Radiation and Its Biological Effects
4. Radiation Effects and Gene Expression in Other Organs
5. Alpha Model, Radiation, and Carcinogenesis
6. Gene Expression Induced by Radiation
6.1. The Ataxia-Telangiectasia Mutated Gene
6.2. Selenoproteins (SEPP1)
6.3. GABA Receptor
6.4. Interleukins
6.5. Epsins 3
6.6. Stefin A (Cystatin A)
6.7. Metallothioneins
7. Relationship between Genes and Clinical Aspects
7.1. Genes Related to Clinical Relevance in Breast Cancer Patients
7.2. Gene Correlation between ATM and Other Genes
7.3. Differential Gene Expression Levels between Breast Tumors and Adjacent Normal Tissues across All TCGA Tumors
7.4. Correlation of ATM Gene and Its Expression with Immune Infiltration Level in Diverse Breast Cancer Types
8. Conclusions
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
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Calaf, G.M.; Crispin, L.A.; Roy, D.; Aguayo, F.; Muñoz, J.P.; Bleak, T.C. Gene Signatures Induced by Ionizing Radiation as Prognostic Tools in an In Vitro Experimental Breast Cancer Model. Cancers 2021, 13, 4571. https://doi.org/10.3390/cancers13184571
Calaf GM, Crispin LA, Roy D, Aguayo F, Muñoz JP, Bleak TC. Gene Signatures Induced by Ionizing Radiation as Prognostic Tools in an In Vitro Experimental Breast Cancer Model. Cancers. 2021; 13(18):4571. https://doi.org/10.3390/cancers13184571
Chicago/Turabian StyleCalaf, Gloria M., Leodan A. Crispin, Debasish Roy, Francisco Aguayo, Juan P. Muñoz, and Tammy C. Bleak. 2021. "Gene Signatures Induced by Ionizing Radiation as Prognostic Tools in an In Vitro Experimental Breast Cancer Model" Cancers 13, no. 18: 4571. https://doi.org/10.3390/cancers13184571