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4,294 Results Found

  • Feature Paper
  • Article
  • Open Access
18 Citations
5,745 Views
11 Pages

Warmer conditions under climate change will alter plant, flower and fruit development in strawberry (Fragaria × ananassa Duch.). Most of the studies examining the relationship between soluble solids content (SSC) and temperature have been condu...

  • Article
  • Open Access
4 Citations
3,630 Views
12 Pages

Identification of Genes of Molecular Marker TGS0892 on Chromosome 6 and Its Mechanism of Soluble Solids Metabolism in Tomato

  • Rong-Rong Zhang,
  • Jian-Ping Tao,
  • Liu-Xia Song,
  • Jia-Qi Zhang,
  • Hui Liu,
  • Wei-Min Zhu,
  • Tong-Min Zhao and
  • Ai-Sheng Xiong

Tomato (Solanum lycopersicum L.) is one of the vegetables widely cultivated in the world, whose fruits are rich in nutrients. Soluble solids content (SSC) is one of the important factors affecting tomato fruit flavor and plays a decisive role in impr...

  • Article
  • Open Access
8 Citations
3,579 Views
16 Pages

17 November 2020

Proper physical properties and standard chemical properties are among the criteria that consumers use to select fruits. Recently, researchers attempted to develop non-destructive methods for measuring properties, among which the near-infrared (NIR) s...

  • Communication
  • Open Access
10 Citations
6,876 Views
8 Pages

12 April 2013

This study presents a novel application of near infrared (NIR) spectral linearisation for measuring the soluble solids content (SSC) of carambola fruits. NIR spectra were measured using reflectance and interactance methods. In this study, only the in...

  • Review
  • Open Access
4 Citations
3,770 Views
26 Pages

Non-Destructive Detection of Soluble Solids Content in Fruits: A Review

  • Ziao Gong,
  • Zhenhua Zhi,
  • Chenglin Zhang and
  • Dawei Cao

Soluble solids content (SSC) in fruits, as one of the key indicators of fruit quality, plays a critical role in postharvest quality assessment and grading. While traditional destructive methods can provide precise measurements of sugar content, they...

  • Review
  • Open Access
1,079 Views
22 Pages

Regulatory Mechanisms of Total Soluble Solids in Tomato: From QTL Mapping to Gene Editing

  • Minghua Xu,
  • Shujing Ji,
  • Shengqun Pang,
  • Yongen Lu,
  • Shouming Li and
  • Wei Xu

29 October 2025

Total Soluble Solids (TSS) in tomatoes is a core indicator for evaluating fruit quality and processing characteristics. Its composition mainly consists of soluble sugars (such as fructose and glucose) and organic acids (such as citric acid and malic...

  • Article
  • Open Access
9 Citations
2,845 Views
11 Pages

14 August 2022

The quality control for fruit maturity inspection is a key issue in fruit packaging and international trade. The quantification of Soluble Solids (SS) in fruits gives a good approximation of the total sugar concentration at the ripe stage, and on the...

  • Article
  • Open Access
21 Citations
3,722 Views
13 Pages

Hyperspectral Imaging with Machine Learning Approaches for Assessing Soluble Solids Content of Tribute Citru

  • Cheng Li,
  • Mengyu He,
  • Zeyi Cai,
  • Hengnian Qi,
  • Jianhong Zhang and
  • Chu Zhang

5 January 2023

Tribute Citru is a natural citrus hybrid with plenty of vitamins and nutrients. Fruits’ soluble solids content (SSC) is a critical quality index. This study used hyperspectral imaging at two spectral ranges (400–1000 nm and 900–1700...

  • Article
  • Open Access
7 Citations
2,354 Views
15 Pages

Nondestructively Determining Soluble Solids Content of Blueberries Using Reflection Hyperspectral Imaging Technique

  • Guangjun Qiu,
  • Biao Chen,
  • Huazhong Lu,
  • Xuejun Yue,
  • Xiangwu Deng,
  • Haishan Ouyang,
  • Bin Li and
  • Xinyu Wei

6 October 2024

Effectively detecting the quality of blueberries is crucial for ensuring that high-quality products are supplied to the fresh market. This study developed a nondestructive method for determining the soluble solids content (SSC) of blueberry fruit by...

  • Article
  • Open Access
747 Views
16 Pages

9 November 2025

Soluble solids content is the most important attribute related to the quality and price of apples. The objective of this study was to detect the soluble solids content (SSC) in ‘Fuji’ apples using hyperspectral imaging combined with a dee...

  • Article
  • Open Access
11 Citations
2,619 Views
12 Pages

26 April 2023

Near-infrared (NIR) spectroscopy is widely used for non-destructive detection of fruit quality, but the transferability of NIR models between different fruits is still a challenge. This study investigates the transferability of NIR models from strawb...

  • Article
  • Open Access
2,038 Views
21 Pages

21 July 2025

The quality of wine largely depends on the quality of wine grapes, which is determined by their chemical composition. Therefore, measuring parameters related to grape ripeness, such as soluble solids content (SSC), is crucial for harvesting high-qual...

  • Article
  • Open Access
17 Citations
3,826 Views
15 Pages

QTL Mapping and GWAS Reveal the Genetic Mechanism Controlling Soluble Solids Content in Brassica napus Shoots

  • Xu Wu,
  • Feng Chen,
  • Xiaozhen Zhao,
  • Chengke Pang,
  • Rui Shi,
  • Changle Liu,
  • Chengming Sun,
  • Wei Zhang,
  • Xiaodong Wang and
  • Jiefu Zhang

11 October 2021

Oilseed–vegetable-dual-purpose (OVDP) rapeseed can effectively alleviate the land contradiction between crops and it supplements vegetable supplies in winter or spring. The soluble solids content (SSC) is an important index that is used to evaluate t...

  • Letter
  • Open Access
31 Citations
5,914 Views
11 Pages

17 October 2020

A portable spectrometric system for nondestructive assessment of the soluble solids content (SSC) of fruits for practical applications has been proposed and its performance has been examined by an experiment on quantitative prediction of the SSC of a...

  • Article
  • Open Access
56 Citations
5,693 Views
24 Pages

7 August 2020

Linear partial least square and non-linear support vector machine regression analysis with various preprocessing techniques and their combinations were used to determine the soluble solids content of hardy kiwi fruits by a handheld, portable near-inf...

  • Article
  • Open Access
5 Citations
2,246 Views
19 Pages

16 June 2024

This study aimed to assess the post-harvest dynamics of seedless conical and mini-conical pepper cultivars in terms of fruit weight loss, dry matter content, and soluble solid content. The above parameters were demonstrated to be effective commercial...

  • Article
  • Open Access
9 Citations
2,653 Views
13 Pages

Fine Mapping and Functional Analysis of Major Regulatory Genes of Soluble Solids Content in Wax Gourd (Benincasa hispida)

  • Wenting Wu,
  • Peng Wang,
  • Xiaochun Huang,
  • Liwen Su,
  • Haixuan Lv,
  • Jiquan Gou,
  • Zhikui Cheng,
  • Lianlian Ma,
  • Wenjin Yu and
  • Zhengguo Liu

Soluble solids content (SSC) is an important quality trait of wax gourd, but reports about its regulatory genes are scarce. In this study, the SSC regulatory gene BhSSC2.1 in wax gourd was mined via quantitative trait locus (QTL) mapping based on hig...

  • Article
  • Open Access
13 Citations
4,439 Views
13 Pages

Total Soluble Solids in Grape Must Estimation Using VIS-NIR-SWIR Reflectance Measured in Fresh Berries

  • Karen Brigitte Mejía-Correal,
  • Víctor Marcelo,
  • Enoc Sanz-Ablanedo and
  • José Ramón Rodríguez-Pérez

29 August 2023

Total soluble solids (TSS) is a key variable taken into account in determining optimal grape maturity for harvest. In this work, partial least square (PLS) regression models were developed to estimate TSS content for Godello, Verdejo (white), Menc&ia...

  • Article
  • Open Access
8 Citations
2,230 Views
15 Pages

The soluble solids content (SSC) of pears is mainly composed of sugars, organic acids, and other soluble substances and is one of the important indices used to measure the sweetness and quality of pear juice. The SSC of pears is mainly composed of su...

  • Article
  • Open Access
7 Citations
2,707 Views
20 Pages

1 November 2024

Kiwifruit, as a climacteric fruit, undergoes rapid ripening and senescence after harvest, making it highly susceptible to softening, rotting, and spoilage. Therefore, monitoring the key quality parameters of kiwifruit, particularly the accurate detec...

  • Article
  • Open Access
3 Citations
1,160 Views
18 Pages

2 April 2025

The soluble solids content (SSC) of blueberry is a key index for evaluating its quality. In view of the demand for rapid non-destructive testing of blueberry SSC and the shortcomings of the existing single-variety testing models in cross-variety appl...

  • Article
  • Open Access
16 Citations
4,211 Views
15 Pages

14 January 2022

Using the framework of aquaphotomics, we have sought to understand the changes within the water structure of kiwifruit juice occurring with changes in temperature. The study focuses on the first (1300–1600 nm) and second (870–1100 nm) ove...

  • Article
  • Open Access
59 Citations
11,186 Views
24 Pages

Prediction of Total Soluble Solids and pH of Strawberry Fruits Using RGB, HSV and HSL Colour Spaces and Machine Learning Models

  • Jayanta Kumar Basak,
  • Bolappa Gamage Kaushalya Madhavi,
  • Bhola Paudel,
  • Na Eun Kim and
  • Hyeon Tae Kim

13 July 2022

Determination of internal qualities such as total soluble solids (TSS) and pH is a paramount concern in strawberry cultivation. Therefore, the main objective of the current study was to develop a non-destructive approach with machine learning algorit...

  • Article
  • Open Access
7 Citations
2,898 Views
20 Pages

26 August 2023

Melon (Cucumis melo L.) is an economically important Cucurbitaceae crop grown around the globe. The sweetness of melon is a significant factor in fruit quality and consumer appeal, and the soluble solids content (SSC) is a key index of melon sweetnes...

  • Article
  • Open Access
13 Citations
4,036 Views
22 Pages

26 November 2019

In this paper we report a method to determine the soluble solids content (SSC) of ‘Rocha’ pear (Pyrus communis L. cv. Rocha) based on their short-wave NIR reflectance spectra (500–1100 nm) measured in conditions similar to those found in packinghouse...

  • Article
  • Open Access
4 Citations
1,128 Views
12 Pages

30 March 2025

Total soluble solids (TSSs) serve as a crucial maturity indicator and quality determinant in apricots, influencing harvest timing and postharvest management decisions. This study develops an advanced framework integrating adaptive boosting (Adaboost)...

  • Article
  • Open Access
6 Citations
3,727 Views
18 Pages

28 March 2024

Soluble solids content (SSC) is one of the main quality indicators of apples, and it is important to improve the precision of online SSC detection of whole apple fruit. Therefore, the spectral pre-processing method of spectral-to-spectral ratio (S/S)...

  • Article
  • Open Access
51 Citations
9,266 Views
12 Pages

11 April 2017

A great interest has recently been focused on lycopene and β-carotene, because of their antioxidant action in the organism. Red-flesh watermelon is one of the main sources of lycopene as the most abundant carotenoid. The use of near-infrared spectros...

  • Feature Paper
  • Article
  • Open Access
2 Citations
3,024 Views
17 Pages

A Quaternary Solid Dispersion System for Improving the Solubility of Olaparib

  • Tae-Han Yun,
  • Jeong-Gyun Lee,
  • Kyu-Ho Bang,
  • Jung-Hyun Cho and
  • Kyeong-Soo Kim

2 January 2025

To improve the low solubility of poorly water soluble olaparib, in the following study, we prepared olaparib-loaded quaternary solid dispersions with hypromellose, Tween 20 or Labrasol, and colloidal silica. The solubility of olaparib with various ty...

  • Article
  • Open Access
6 Citations
3,844 Views
22 Pages

Enhancing the Solubility and Dissolution of Apigenin: Solid Dispersions Approach

  • Natalia Rosiak,
  • Ewa Tykarska,
  • Andrzej Miklaszewski,
  • Robert Pietrzak and
  • Judyta Cielecka-Piontek

Apigenin (APG), a bioactive flavonoid with promising therapeutic potential, suffers from poor water solubility, which limits its bioavailability. To address this, solid dispersions of APG were prepared using ball milling with sodium alginate (SA), Pl...

  • Article
  • Open Access
741 Views
15 Pages

Effect of Mixing Entropy on the Solid Solubility of Lanthanum in Fe Alloys

  • Wenhao Guan,
  • Wei Qu,
  • Zhigang Liang,
  • Huiping Ren,
  • Zhili Li,
  • Zhouli Liu,
  • Cheng Ji,
  • Wenbin Zhang,
  • Haoyuan Sun and
  • Jiangsen Song

23 March 2025

A solid solution of rare-earth atoms in the iron matrix is a prerequisite for the microalloying effect in steels. However, to date, there has been considerable controversy regarding whether rare-earth atoms can form solid solutions within the iron ma...

  • Review
  • Open Access
49 Citations
5,262 Views
12 Pages

Physicochemical characterization is a crucial step for the successful development of solid dispersions, including the determination of drug crystallinity and molecular interactions. Typically, the detection of molecular interactions will assist in th...

  • Article
  • Open Access
38 Citations
5,313 Views
20 Pages

This study aimed to improve the solubility and dissolution of aprepitant, a drug with poor aqueous solubility, using a phosphatidylcholine (PC)-based solid dispersion system. When fabricating the PC-based solid dispersion, we employed mesoporous micr...

  • Article
  • Open Access
36 Citations
6,249 Views
18 Pages

Solubility Improvement of Progesterone from Solid Dispersions Prepared by Solvent Evaporation and Co-milling

  • Xing Chen,
  • Ioannis Partheniadis,
  • Ioannis Nikolakakis and
  • Hisham Al-Obaidi

7 April 2020

The aim of this contribution was to evaluate the impact of processing methods and polymeric carriers on the physicochemical properties of solid dispersions of the poorly soluble drug progesterone (PG). Five polymers: hydroxypropyl methylcellulose (HP...

  • Article
  • Open Access
2 Citations
1,415 Views
19 Pages

Advancing Loquat Total Soluble Solids Content Determination by Near-Infrared Spectroscopy and Explainable AI

  • Yizhi Luo,
  • Qingting Jin,
  • Huazhong Lu,
  • Peng Li,
  • Guangjun Qiu,
  • Haijun Qi,
  • Bin Li and
  • Xingxing Zhou

TSSC is one of the most important factors affecting loquat flavor, consumer satisfaction, and market competitiveness. To improve the ability to assess the TSSC of loquats, a method leveraging near-infrared spectroscopy and explainable artificial inte...

  • Article
  • Open Access
15 Citations
2,837 Views
12 Pages

4 December 2020

In Cu-Cr alloys, the strengthening effects of Cr are severely limited due to the relatively low Cr solid solubility in Cu matrix. In addition, apart from the dissolved Cr, it should be noted that high proportion of Cr in Cu matrix work as the second...

  • Article
  • Open Access
27 Citations
4,555 Views
20 Pages

The purpose of this study is to improve the solubility and dissolution of a poorly soluble drug, Irbesartan, using solid dispersion techniques. For that purpose, different polymers such as Soluplus®, Kollidon® VA 64, Kolliphor® P 407, and...

  • Article
  • Open Access
3 Citations
1,834 Views
17 Pages

The Effect of Isoniazid–Maltitol Solid Dispersions on Aqueous Solubility and Permeability

  • Madan Sai Poka,
  • Marnus Milne,
  • Anita Wessels and
  • Marique Aucamp

2 November 2023

Maltitol (MAL) is a well-known polyol with potential pharmaceutical applications. Unlike other polyols, its utilization as a carrier for solid dispersions (SDs) has not been adequately investigated. This research studied the feasibility of MAL as an...

  • Article
  • Open Access
7 Citations
4,104 Views
15 Pages

Loratadine (LRD), a non-sedating and slow-acting antihistamine, is often given in combination with short-onset chlorpheniramine maleate (CPM) to increase efficacy. However, LRD has poor water solubility resulting in low bioavailability. The aim of th...

  • Article
  • Open Access
15 Citations
4,407 Views
15 Pages

Honokiol (HK), a well-tolerated natural product, has many multiple pharmacological activities. However, its poor water solubility and low bioavailability limit its clinical application and development. The aim of this research was to prepare the soli...

  • Article
  • Open Access
18 Citations
4,434 Views
12 Pages

Development of the Amorphous Solid Dispersion of Curcumin: A Rational Selection of Polymers for Enhanced Solubility and Dissolution

  • Memoona Ishtiaq,
  • Sajid Asghar,
  • Ikram Ullah Khan,
  • Muhammad Shahid Iqbal and
  • Syed Haroon Khalid

10 November 2022

The goal of this investigation was to determine the effectiveness of hydrophilic polymers in preparing a solid dispersion to enhance the solubility and dissolution of poorly water-soluble drugs, such as curcumin. In order to prepare the solid dispers...

  • Article
  • Open Access
7 Citations
6,238 Views
28 Pages

Background/Objectives: This study aims to develop a solid self-nanoemulsifying drug delivery system (SNEDDS) to enhance the solubility and oral bioavailability of cannabidiol (CBD). Methods: According to the solubility of CBD and pseudo-ternary phase...

  • Article
  • Open Access
504 Views
15 Pages

1 December 2025

To meet market demand for fresh ‘Dinosaur Egg’ Apricot plum and realize effective quality classification, this study developed a non-destructive quality evaluation method using near-infrared spectroscopy (NIRS) with cross-parameter featur...

  • Article
  • Open Access
9 Citations
3,061 Views
18 Pages

Safety and Pharmaceutical Evaluation of a Novel Natural Polymer, Ocicum, as Solubility and Dissolution Enhancer in Solid Dispersion

  • Mobina Manzoor,
  • Syed Atif Raza,
  • Mulazim Hussain Asim,
  • Nadeem Irfan Bukhari,
  • Shumaila Arshad and
  • Uzma Zafar

Plant mucilages are commonly employed as excipients in pharmaceutical manufacturing. Ocimum basilicum (Lamiaceae family), a source of hydrophilic mucilage referred herein as Ocicum, was evaluated for the solubility enhancer of a model drug, aceclofen...

  • Article
  • Open Access
17 Citations
5,253 Views
15 Pages

Preparation of Apixaban Solid Dispersion for the Enhancement of Apixaban Solubility and Permeability

  • Juseung Lee,
  • Jong-Ju Lee,
  • Seungyeol Lee,
  • Linh Dinh,
  • Hangyu Oh,
  • Sharif Md Abuzar,
  • Jun-Hyun Ahn and
  • Sung-Joo Hwang

(1) Background: Solid dispersion (SD) can help increase the bioavailability of poorly water-soluble drugs. Meanwhile, apixaban (APX)—a new anticoagulation drug—has low water solubility (0.028 mg/mL) and low intestinal permeability (0.9 &t...

  • Article
  • Open Access
6 Citations
6,338 Views
11 Pages

Hildebrand and Hansen solubility parameters, and log P value are widely used to determine the solubility of polymers in solvents. The models were used to explain the recovery of phytochemical, rosmarinic acid from Orthosiphon aristatus extract in C18...

  • Review
  • Open Access
63 Citations
8,275 Views
33 Pages

Analytical and Computational Methods for the Estimation of Drug-Polymer Solubility and Miscibility in Solid Dispersions Development

  • Djordje Medarević,
  • Jelena Djuriš,
  • Panagiotis Barmpalexis,
  • Kyriakos Kachrimanis and
  • Svetlana Ibrić

The development of stable solid dispersion formulations that maintain desired improvement of drug dissolution rate during the entire shelf life requires the analysis of drug-polymer solubility and miscibility. Only if the drug concentration is below...

  • Article
  • Open Access
8 Citations
2,659 Views
25 Pages

Solid Dispersions Obtained by Ball Milling as Delivery Platform of Etodolac, a Model Poorly Soluble Drug

  • Anna Czajkowska-Kośnik,
  • Iwona Misztalewska-Turkowicz,
  • Agnieszka Zofia Wilczewska,
  • Anna Basa and
  • Katarzyna Winnicka

7 August 2024

Poor water solubility of drugs is a limiting factor for their bioavailability and pharmacological activity. Many approaches are known to improve drug solubility, and among them, the physical method, solid dispersions (SDs), is applied. SDs are physic...

  • Article
  • Open Access
39 Citations
4,174 Views
12 Pages

4 September 2020

Soluble solids content (SSC) is one of the important components for evaluating fruit quality. The rapid development of hyperspectral imagery provides an efficient method for non-destructive detection of SSC. Previous studies have shown that the inter...

  • Review
  • Open Access
4 Citations
5,248 Views
26 Pages

The solubility behavior of drugs is a critical factor in formulation development. Approximately 40–45% of new drugs face market entry challenges due to low water solubility. Enhancing drug bioavailability is thus essential in developing pharmac...

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