Drug Polymorphism and Dosage Form Design

Dear Colleagues,

We are pleased to announce the new Special Issue for Pharmaceutics entitled “Drug Polymorphism and Dosage Form Design”.

Extensive academic and industrial research demonstrated that more than 50% of the currently used APIs  shows multiple physical arrangement of the constituents in the crystal lattice. This polymorphism significantly influences a variety of drug properties, including dissolution rate, solubility, tabletability, flowability, stability and even bioavailability, efficacy and toxicity. Pioneered by Aguiar et al in the ‘60s, surprisingly, after many decades, this research area is still attracting much attention by the scientific community and motivated the edition of this Special Issue, that is aimed at gathering the most recent advances in the field of polymorphism, highlighting its relevance in the Pharmaceutical Sciences and in the Design of Dosage Forms.

Original research articles and review articles dealing with all the aspects of drug polymorphism are considered. Particularly, the discovery of new crystal forms, methods for their preparation, influence of the polymorphism on the physicochemical properties, analytical methods for the study of crystal forms, API stability during processing and storage, biological effects of polymorphism, preformulation studies, design of dosage forms and  regulatory implications are all included in this Special Issue.

Dr. Roberta Censi
Prof. Dr. Piera Di Martino
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.