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76 Results Found

  • Article
  • Open Access
542 Views
22 Pages

11 November 2025

This study aimed to model the effects of aw, pH, and OA, a compound commonly used as a plant elicitor, on the growth and mycotoxin production of Aspergillus welwitschiae and Aspergillus flavus on a fig-based model substrate. Using RSM with a BBD, the...

  • Article
  • Open Access
2,160 Views
21 Pages

BRAF Detection in FNAC Combined with Semi-Quantitative 99mTc-MIBI Technique and AI Model, an Economic and Efficient Predicting Tool for Malignancy in Thyroid Nodules

  • Laura Teodoriu,
  • Maria-Christina Ungureanu,
  • Mioara Matei,
  • Irena Grierosu,
  • Alexandra Iuliana Saviuc,
  • Jalloul Wael,
  • Iuliu Ivanov,
  • Loredana Dragos,
  • Radu Danila and
  • Cipriana Stefanescu
  • + 4 authors

Background: Technology allows us to predict a histopathological diagnosis, but the high costs prevent the large-scale use of these possibilities. The current liberal indication for surgery in benign thyroid conditions led to a rising frequency of inc...

  • Article
  • Open Access
2 Citations
2,158 Views
14 Pages

27 January 2024

This research evaluated the modified RCTU score, derived from amyloid PET scans, for predicting the progression from amnestic Mild Cognitive Impairment (aMCI) to Alzheimer’s Disease (AD). aMCI patients underwent baseline evaluations, including...

  • Article
  • Open Access
10 Citations
3,506 Views
11 Pages

Immune Checkpoint Inhibitors in Advanced NSCLC: [18F]FDG PET/CT as a Troubleshooter in Treatment Response

  • Cristina Ferrari,
  • Giulia Santo,
  • Nunzio Merenda,
  • Alessia Branca,
  • Paolo Mammucci,
  • Pamela Pizzutilo,
  • Cosmo Damiano Gadaleta and
  • Giuseppe Rubini

15 September 2021

Introduction: The aim of this study was to investigate whether [18F]FDG PET/CT-derived semi-quantitative parameters can predict immunotherapy treatment response in non-small cell lung cancer (NSCLC) patients. Secondly, immune-related adverse events (...

  • Article
  • Open Access
16 Citations
6,844 Views
11 Pages

30 April 2015

Methicillin-resistant Staphylococcus aureus (MRSA) is a significant cause of hospital-associated pneumonia (HAP). The rapid identification of MRSA would be beneficial for early diagnosis. The study aimed to evaluate a multilocus, fluorescence-base...

  • Article
  • Open Access
4 Citations
2,087 Views
14 Pages

Semi-Quantification of Myocardial Uptake of Bone-Seeking Agents in Suspected Cardiac Amyloidosis

  • Cristina Campi,
  • Chiara Briani,
  • Alessandro Salvalaggio,
  • Chiara Giraudo,
  • Alberto Cipriani,
  • Alessandro Zorzi,
  • Pietro Zucchetta,
  • Roberto Vettor and
  • Diego Cecchin

Introduction: Bone scintigraphy has emerged as a key tool for non-invasive etiologic diagnosis of transthyretin (ATTR) cardiac amyloidosis (CA). We focused on a new semi-quantification method (on planar imaging) that could complement the qualitative/...

  • Article
  • Open Access
6 Citations
2,541 Views
10 Pages

Lesion-to-Liver SUVmax Ratio to Improve the Prognostic Value of the End of Treatment PET/CT in Diffuse Large B-Cell Lymphoma

  • Cristina Ferrari,
  • Antonio Rosario Pisani,
  • Tamara Masi,
  • Giulia Santo,
  • Paolo Mammucci,
  • Dino Rubini,
  • Angela Sardaro and
  • Giuseppe Rubini

21 September 2022

Background: Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma worldwide. After first-line therapy, 30–40% of patients relapse or experiment with refractory disease. 18F-FDG PET/CT represents a validated diagnostic to...

  • Article
  • Open Access
1 Citations
2,870 Views
19 Pages

The Role of the 18F-FDG PET/CT in the Management of Patients Suspected of Cardiac Implantable Electronic Devices’ Infection

  • Antonio Rosario Pisani,
  • Dino Rubini,
  • Corinna Altini,
  • Rossella Ruta,
  • Maria Gazzilli,
  • Angela Sardaro,
  • Francesca Iuele,
  • Nicola Maggialetti and
  • Giuseppe Rubini

4 January 2024

Background: Infection of Cardiac Implantable Electronic Devices (CIEDI) is a real public health problem. The main aim of this study was to determine the diagnostic performance of 18F-FDG PET/CT in the diagnosis of CIEDI. Methods: A total of 48 patien...

  • Article
  • Open Access
15 Citations
3,820 Views
13 Pages

Diagnostic Performance of 99mTc-Methoxy-Isobuty-Isonitrile (MIBI) for Risk Stratification of Hypofunctioning Thyroid Nodules: A European Multicenter Study

  • Simone Agnes Schenke,
  • Alfredo Campennì,
  • Murat Tuncel,
  • Gianluca Bottoni,
  • Sait Sager,
  • Tatjana Bogovic Crncic,
  • Damir Rozic,
  • Rainer Görges,
  • Pinar Pelin Özcan and
  • Luca Giovanella
  • + 4 authors

99mTc-MIBI (MIBI) imaging is able to exclude malignancy of hypofunctioning thyroid nodules (TNs) with high probability but false positive results are frequent due to low specificity. Therefore, pre-test selection of appropriate TNs is crucial. For im...

  • Article
  • Open Access
1 Citations
1,170 Views
12 Pages

Using [18F]FDG PET/CT to Identify Optimal Responders to Neoadjuvant Therapy in Breast Cancer—Results from a Prospective Patient Cohort

  • Fabrizia Gelardi,
  • Paola Tiberio,
  • Rosalba Torrisi,
  • Roberta Zanca,
  • Marcello Rodari,
  • Alberto Zambelli,
  • Armando Santoro,
  • Bethania Fernandes,
  • Andrea Sagona and
  • Lidija Antunovic
  • + 6 authors

25 June 2025

Background/objectives: Pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in breast cancer (BC) is a solid indicator of favourable prognosis, potentially also being useful for more conservative patient management. We aim to explor...

  • Article
  • Open Access
342 Views
20 Pages

Fingernail Onychomycosis: A Laboratory-Based Retrospective Study with Species Profiling and Antifungal Susceptibility of Yeasts

  • Paweł Krzyściak,
  • Zuzanna Tokarz,
  • Monika Pomorska-Wesołowska,
  • Magdalena Skóra,
  • Andrzej Kazimierz Jaworek and
  • Jadwiga Wójkowska-Mach

1 January 2026

Background/Objectives: Fingernail onychomycosis differs etiologically and epidemiologically from toenail infections and is frequently complicated by colonization and mixed growth. Reliable interpretation of microscopy–culture correlations is es...

  • Feature Paper
  • Article
  • Open Access
13 Citations
6,176 Views
14 Pages

Tracking Extracellular Matrix Remodeling in Lungs Induced by Breast Cancer Metastasis. Fourier Transform Infrared Spectroscopic Studies

  • Karolina Chrabaszcz,
  • Katarzyna Kaminska,
  • Karolina Augustyniak,
  • Monika Kujdowicz,
  • Marta Smeda,
  • Agnieszka Jasztal,
  • Marta Stojak,
  • Katarzyna M. Marzec and
  • Kamilla Malek

6 January 2020

This work focused on a detailed assessment of lung tissue affected by metastasis of breast cancer. We used large-area chemical scanning implemented in Fourier transform infrared (FTIR) spectroscopic imaging supported with classical histological and m...

  • Article
  • Open Access
38 Citations
26,127 Views
14 Pages

Can Public Health Risk Assessment Using Risk Matrices Be Misleading?

  • Shabnam Vatanpour,
  • Steve E. Hrudey and
  • Irina Dinu

The risk assessment matrix is a widely accepted, semi-quantitative tool for assessing risks, and setting priorities in risk management. Although the method can be useful to promote discussion to distinguish high risks from low risks, a published crit...

  • Article
  • Open Access
10 Citations
4,664 Views
22 Pages

Proteomic and Bioinformatic Analysis of Streptococcus suis Human Isolates: Combined Prediction of Potential Vaccine Candidates

  • Esther Prados de la Torre,
  • Antonio Rodríguez-Franco and
  • Manuel J. Rodríguez-Ortega

18 April 2020

Streptococcus suis is a Gram-positive bacterium responsible for major infections in pigs and economic losses in the livestock industry, but also an emerging zoonotic pathogen causing serious diseases in humans. No vaccine is available so far against...

  • Article
  • Open Access
9 Citations
5,034 Views
14 Pages

Detection of Microorganisms in Body Fluids via MTT-PMS Assay

  • Cheng-Han Chen,
  • Yu-Ting Tsao,
  • Po-Ting Yeh,
  • Yu-Hsiang Liao,
  • Yi-Tzu Lee,
  • Wan-Ting Liao,
  • Yung-Chih Wang,
  • Ching-Fen Shen and
  • Chao-Min Cheng

Early detection of microorganisms is essential for the management of infectious diseases. However, this is challenging, as traditional culture methods are labor-intensive and time-consuming. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium br...

  • Article
  • Open Access
2 Citations
1,348 Views
16 Pages

The Dammiss EEG Score: A New System to Quantify EEG Abnormalities and Predict the Outcome in Asphyxiated Newborns

  • Fabrizio Ferrari,
  • Carolina Bondi,
  • Licia Lugli,
  • Luca Bedetti,
  • Isotta Guidotti,
  • Federico Banchelli,
  • Laura Lucaccioni and
  • Alberto Berardi

12 March 2025

Background: The aim of the study was to evaluate a novel EEG scoring system as a diagnostic and prognostic tool for brain injury in infants who had experienced perinatal asphyxia. Methods: The scoring system, based on a semi-quantitative approach, en...

  • Article
  • Open Access
7 Citations
3,638 Views
13 Pages

Evaluation of Salivary Indoxyl Sulfate with Proteinuria for Predicting Graft Deterioration in Kidney Transplant Recipients

  • Natalia Korytowska,
  • Aleksandra Wyczałkowska-Tomasik,
  • Leszek Pączek and
  • Joanna Giebułtowicz

16 August 2021

Acute kidney injury (AKI) is a significant risk factor for developing chronic kidney disease and progression to end-stage renal disease in elderly patients. AKI is also a relatively common complication after kidney transplantation (KTx) associated wi...

  • Article
  • Open Access
2 Citations
3,775 Views
23 Pages

24 December 2024

Despite various opportunities, urban development projects have been causing significant challenges to the preservation and conservation of historic cultural heritage. In particular, an increasing number of World Heritage (WH) properties are impacted...

  • Article
  • Open Access
175 Citations
14,078 Views
14 Pages

The Comparative Validity and Reproducibility of a Diet Quality Index for Adults: The Australian Recommended Food Score

  • Clare E. Collins,
  • Tracy L. Burrows,
  • Megan E. Rollo,
  • May M. Boggess,
  • Jane F. Watson,
  • Maya Guest,
  • Kerith Duncanson,
  • Kristine Pezdirc and
  • Melinda J. Hutchesson

23 January 2015

Adult diet quality indices are shown to predict nutritional adequacy of dietary intake as well as all-cause morbidity and mortality. This study describes the reproducibility and validity of a food-based diet quality index, the Australian Recommended...

  • Article
  • Open Access
525 Views
28 Pages

12 December 2025

Coastal erosion poses a significant risk to the Romanian Black Sea coast, a region characterized by the interaction of natural geomorphological processes and anthropogenic pressures. The research focuses on developing a tool to quantify the cumulativ...

  • Article
  • Open Access
807 Views
12 Pages

Synergistic Imaging: Combined Lung Ultrasound and Low-Dose Chest CT for Quantitative Assessment of COVID-19 Severity—A Prospective Observational Study

  • Andrzej Górecki,
  • Piotr Piech,
  • Karolina Kołodziejczyk,
  • Ada Jankowska,
  • Zuzanna Szostak,
  • Anna Bronikowska,
  • Bartosz Borowski and
  • Grzegorz Staśkiewicz

Background/Objectives: To assess quantitatively the correlation between the lung ultrasound severity scores (LUSSs) and chest CT severity scores (CTSSs) derived from low-dose computed tomography (LDCT) for evaluating pulmonary inflammation in COVID-1...

  • Feature Paper
  • Article
  • Open Access
12 Citations
3,357 Views
11 Pages

Serum microRNAs as Tool to Predict Early Response to Benralizumab in Severe Eosinophilic Asthma

  • José A. Cañas,
  • Marcela Valverde-Monge,
  • José M. Rodrigo-Muñoz,
  • Beatriz Sastre,
  • Marta Gil-Martínez,
  • Raquel García-Latorre,
  • Manuel J. Rial,
  • Aida Gómez-Cardeñosa,
  • Mar Fernández-Nieto and
  • Victoria del Pozo
  • + 4 authors

28 January 2021

Severe eosinophilic asthma poses a serious health and economic problem, so new therapy approaches have been developed to control it, including biological drugs such as benralizumab, which is a monoclonal antibody that binds to IL-5 receptor alpha sub...

  • Article
  • Open Access
16 Citations
3,703 Views
16 Pages

Simulation of the Attrition of Recycled Concrete Aggregates during Concrete Mixing

  • Jaime Moreno-Juez,
  • Luís Marcelo Tavares,
  • Riccardo Artoni,
  • Rodrigo M. de Carvalho,
  • Emerson Reikdal da Cunha and
  • Bogdan Cazacliu

1 June 2021

Concrete mixing can lead to mechanical degradation of aggregates, particularly when dealing with recycled concrete aggregates. In this work, the attrition of such materials during mixing is studied by means of experiments and simulations. The effect...

  • Article
  • Open Access
7 Citations
4,636 Views
15 Pages

24 August 2021

Despite different approaches used to assign the risk scores for missing information in productivity susceptibility analysis (PSA)—a widely used semi-quantitative risk assessment tool for target and non-target fisheries stocks—for the selected attribu...

  • Article
  • Open Access
15 Citations
3,007 Views
10 Pages

Association between Visceral Adipose Tissue and Non-Alcoholic Steatohepatitis Histology in Patients with Known or Suspected Non-Alcoholic Fatty Liver Disease

  • Ilkay S. Idilman,
  • Hsien Min Low,
  • Tolga Gidener,
  • Kenneth Philbrick,
  • Taofic Mounajjed,
  • Jiahui Li,
  • Alina M. Allen,
  • Meng Yin and
  • Sudhakar K. Venkatesh

10 June 2021

(1) Purpose: To determine the association between visceral adipose tissue (VAT) and proton density fat fraction (PDFF) with magnetic resonance imaging (MRI), and hepatic steatosis (HS), non-alcoholic steatohepatitis (NASH) and hepatic fibrosis (HF) i...

  • Article
  • Open Access
10 Citations
3,203 Views
13 Pages

Is There a Relationship between the Elasticity of Brain Tumors, Changes in Diffusion Tensor Imaging, and Histological Findings? A Pilot Study Using Intraoperative Ultrasound Elastography

  • Santiago Cepeda,
  • Sergio García-García,
  • María Velasco-Casares,
  • Gabriel Fernández-Pérez,
  • Tomás Zamora,
  • Ignacio Arrese and
  • Rosario Sarabia

21 February 2021

Intraoperative ultrasound elastography (IOUS-E) is a novel image modality applied in brain tumor assessment. However, the potential links between elastographic findings and other histological and neuroimaging features are unknown. This study aims to...

  • Article
  • Open Access
1 Citations
2,668 Views
16 Pages

Association of Low Protein-to-Carbohydrate Energy Ratio with Cognitive Impairment in Elderly Type 2 Diabetes Patients

  • Antelm Pujol,
  • Pilar Sanchis,
  • María I. Tamayo,
  • Samantha Godoy,
  • Pilar Andrés,
  • Aleksandra Speranskaya,
  • Ana Espino,
  • Ana Estremera,
  • Elena Rigo and
  • Lluís Masmiquel
  • + 6 authors

14 November 2024

Background/Objectives: The relationship between macronutrient intake and cognitive decline in older adults with type 2 diabetes mellitus (T2DM) remains underexplored. Methods: This cross-sectional study aimed to evaluate the association between the p...

  • Article
  • Open Access
3,349 Views
15 Pages

4 April 2025

An in vitro 3D model using fungus colonized Reconstructed Human Epidermis (RHE) represents an effective preclinical model to simulate the pathological conditions of onychomycosis. We evaluated the suitability of this 3D onychomycosis model and use it...

  • Article
  • Open Access
5 Citations
4,236 Views
10 Pages

Can AI Automatically Assess Scan Quality of Hip Ultrasound?

  • Abhilash Rakkunedeth Hareendrananthan,
  • Myles Mabee,
  • Baljot S. Chahal,
  • Sukhdeep K. Dulai and
  • Jacob L. Jaremko

18 April 2022

Ultrasound images can reliably detect Developmental Dysplasia of the Hip (DDH) during early infancy. Accuracy of diagnosis depends on the scan quality, which is subjectively assessed by the sonographer during ultrasound examination. Such assessment i...

  • Article
  • Open Access
826 Views
25 Pages

Semi-rigid tool polishing is widely used in the high-precision manufacturing of electroless nickel surface due to its stable material removal and high efficiency in correcting mid- and high-frequency profile errors. However, predicting mid-frequency...

  • Article
  • Open Access
5 Citations
2,637 Views
14 Pages

18 August 2023

Modeling the windborne transmission of aerosolized pathogens is challenging. We adapted an atmospheric dispersion model named the Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) model to simulate the windborne dispersion of porcine...

  • Article
  • Open Access
1 Citations
2,622 Views
13 Pages

High Frequency of Osteophytes Detected by High-Resolution Ultrasound at the Finger Joints of Asymptomatic Factory Workers

  • Mario Giulini,
  • Ralph Brinks,
  • Stefan Vordenbäumen,
  • Hasan Acar,
  • Jutta G. Richter,
  • Xenofon Baraliakos,
  • Benedikt Ostendorf,
  • Matthias Schneider,
  • Oliver Sander and
  • Philipp Sewerin

30 August 2023

Hand Osteoarthritis (HOA) is a frequently occurring musculoskeletal disease that impacts health. Diagnostic criteria often incorporate osteophytes documented through imaging procedures. Radiographic imaging is considered the gold standard; however, m...

  • Article
  • Open Access
26 Citations
5,055 Views
22 Pages

Predictive Value of Precision-Cut Lung Slices for the Susceptibility of Three Animal Species for SARS-CoV-2 and Validation in a Refined Hamster Model

  • Nora M. Gerhards,
  • Jan B. W. J. Cornelissen,
  • Lucien J. M. van Keulen,
  • José Harders-Westerveen,
  • Rianka Vloet,
  • Bregtje Smid,
  • Stéphanie Vastenhouw,
  • Sophie van Oort,
  • Renate W. Hakze-van der Honing and
  • Nadia Oreshkova
  • + 7 authors

In assessing species susceptibility for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and in the search for an appropriate animal model, multiple research groups around the world inoculated a broad range of animal species using variou...

  • Systematic Review
  • Open Access
21 Citations
3,613 Views
18 Pages

Magnetic Resonance Imaging-Based Predictive Models for Clinically Significant Prostate Cancer: A Systematic Review

  • Marina Triquell,
  • Miriam Campistol,
  • Ana Celma,
  • Lucas Regis,
  • Mercè Cuadras,
  • Jacques Planas,
  • Enrique Trilla and
  • Juan Morote

29 September 2022

MRI can identify suspicious lesions, providing the semi-quantitative risk of csPCa through the Prostate Imaging-Report and Data System (PI-RADS). Predictive models of clinical variables that individualise the risk of csPCa have been developed by addi...

  • Article
  • Open Access
6 Citations
2,835 Views
9 Pages

Qualitative and Semiquantitative Parameters of 18F-FDG-PET/CT as Predictors of Malignancy in Patients with Solitary Pulmonary Nodule

  • Ferdinando Corica,
  • Maria Silvia De Feo,
  • Maria Lina Stazza,
  • Maria Rondini,
  • Andrea Marongiu,
  • Viviana Frantellizzi,
  • Susanna Nuvoli,
  • Alessio Farcomeni,
  • Giuseppe De Vincentis and
  • Angela Spanu

4 February 2023

This study aims to evaluate the reliability of qualitative and semiquantitative parameters of 18F-FDG PET-CT, and eventually a correlation between them, in predicting the risk of malignancy in patients with solitary pulmonary nodules (SPNs) before th...

  • Article
  • Open Access
89 Citations
5,785 Views
15 Pages

18F-FDG Pet Parameters and Radiomics Features Analysis in Advanced Nsclc Treated with Immunotherapy as Predictors of Therapy Response and Survival

  • Giulia Polverari,
  • Francesco Ceci,
  • Valentina Bertaglia,
  • Maria Lucia Reale,
  • Osvaldo Rampado,
  • Elena Gallio,
  • Roberto Passera,
  • Virginia Liberini,
  • Paola Scapoli and
  • Désirée Deandreis
  • + 4 authors

5 May 2020

Objectives: (1.1) to evaluate the association between baseline 18F-FDG PET/CT semi-quantitative parameters of the primary lesion with progression free survival (PFS), overall survival (OS) and response to immunotherapy, in advanced non-small cell lun...

  • Article
  • Open Access
2,031 Views
16 Pages

Bone Scintigraphy in Cardiac Transthyretin-Related Amyloidosis: A Novel Time-Saving Tool for Semiquantitative Analysis, with Good Potential for Predicting Different Etiologies

  • Susanna Mattoni,
  • Maria Francesca Morrone,
  • Giuseppe Della Gala,
  • Sonia Elisa Prisco,
  • Maurizio Sguazzotti,
  • Giulia Saturi,
  • Simone Longhi,
  • Stefano Fanti,
  • Rachele Bonfiglioli and
  • Lidia Strigari

31 October 2024

(1) Background: The visual and semiquantitative analysis of Technetium-99metastable-3,3-diphospono-1,2-propanodicarboxylic acid (99mTc-DPD) bone scintigraphy is promising for diagnosing cardiac amyloidosis but time-consuming. We validated a faster me...

  • Article
  • Open Access
1,666 Views
12 Pages

Predictive Value of Quantitative Parameters of 18F-FDG PET/CT in Patients with Liposarcoma

  • Lucia Martiniova,
  • Serageldin Kamel,
  • Kalevi Kairemo,
  • Robert Benjamin,
  • Neeta Somaiah,
  • Gregory Ravizzini and
  • Elise F. Nassif Haddad

12 September 2024

The purpose of this study was to evaluate the predictive features of baseline F-18-fluorodeoxy-D-glucose positron emission tomography (18F-FDG PET)/computed tomography (CT) parameters in patients with dedifferentiated liposarcomas (DDLPSs) and well-d...

  • Article
  • Open Access
1 Citations
2,369 Views
12 Pages

Nonlocal Effective Medium (NLEM) for Quantitative Modelling of Nanoroughness in Spectroscopic Reflectance

  • Eleftheria Lampadariou,
  • Konstantinos Kaklamanis,
  • Dimitrios Goustouridis,
  • Ioannis Raptis and
  • Elefterios Lidorikis

Spectroscopic reflectance is a versatile optical methodology for the characterization of transparent and semi-transparent thin films in terms of thickness and refractive index. The Fresnel equations are used to interpret the measurements, but their a...

  • Review
  • Open Access
401 Views
25 Pages

Structural Performance of Semi-Rigid Beam-to-Column Connections in Steel Storage Racks: A Review Focused on FEM Analysis

  • Mirjana Piskulic,
  • Rodoljub Vujanac,
  • Snezana Vulović,
  • Nenad Miloradovic,
  • Mirko Blagojevic and
  • Zorica Djordjevic

19 December 2025

In practical applications, steel storage racks include a wide range of beam-to-column connections (BCCs), which have a significant impact on their structural stability, particularly under various loading conditions. This systematic review focuses on...

  • Article
  • Open Access
4 Citations
3,138 Views
18 Pages

Comparative Assessment of Wildland Fire Rate of Spread Models: Effects of Wind Velocity

  • Dionysios I. Kolaitis,
  • Christos Pallikarakis and
  • Maria A. Founti

4 May 2023

Wildland fire rate of spread prediction models are important tools for the effective coordination of resident evacuation and fire suppression efforts. A comparative assessment of ten empirical and semi-empirical rate of spread prediction models is pe...

  • Article
  • Open Access
9 Citations
2,785 Views
18 Pages

[18F]Fluciclovine PET/CT Improves the Clinical Management of Early Recurrence Prostate Cancer Patients

  • Anna Giulia Nappi,
  • Cristina Ferrari,
  • Paolo Mammucci,
  • Dino Rubini,
  • Valentina Lavelli,
  • Angela Sardaro,
  • Antonio Rosario Pisani and
  • Giuseppe Rubini

12 March 2022

We investigated the [18F]Fluciclovine PET/CT reliability in the early detection of recurrent prostate cancer (PCa) and its impact on therapeutic decision making. We retrospectively analyzed 58 [18F]Fluciclovine PET/CT scans performed to identify earl...

  • Review
  • Open Access
15 Citations
10,232 Views
20 Pages

31 March 2020

The increasing emergence of drug-resistant tuberculosis requires new effective and safe drug regimens. However, drug discovery and development are challenging, lengthy and costly. The framework of model-informed drug discovery and development (MID3)...

  • Article
  • Open Access
1,453 Views
28 Pages

Maximizing Diagnostic Yield in Intellectual Disability Through Exome Sequencing: Genotype–Phenotype Insights in a Vietnamese Cohort

  • Thu Lan Hoang,
  • Thi Kim Phuong Doan,
  • Thi Ngoc Lan Hoang,
  • Cam Tu Ho,
  • Thi Ha Vu,
  • Thi Trang Nguyen,
  • Thi Huyen Vu,
  • Thi Trang Dao,
  • Thi Minh Ngoc Nguyen and
  • Thi Lan Anh Luong
  • + 9 authors

7 November 2025

Background: Intellectual disability (ID) is a heterogeneous condition caused by diverse genetic factors, including single-nucleotide variants (SNVs) and copy number variants (CNVs). Whole-exome sequencing (WES) and clinical exome sequencing (CES) hav...

  • Article
  • Open Access
19 Citations
2,752 Views
12 Pages

The Value of Semiquantitative Parameters Derived from 18F-FDG PET/CT for Predicting Response to Neoadjuvant Chemotherapy in a Cohort of Patients with Different Molecular Subtypes of Breast Cancer

  • Luca Urso,
  • Laura Evangelista,
  • Pierpaolo Alongi,
  • Natale Quartuccio,
  • Corrado Cittanti,
  • Ilaria Rambaldi,
  • Naima Ortolan,
  • Francesca Borgia,
  • Alberto Nieri and
  • Mirco Bartolomei
  • + 4 authors

29 November 2022

Pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) is a strong prognostic factor in breast cancer (BC). The aim of this study was to investigate whether semiquantitative parameters derived from baseline [18F]Fluorodeoxyglucose...

  • Article
  • Open Access
4 Citations
5,133 Views
15 Pages

2 November 2022

Soot molecules are hazardous compounds threatening human health. Computational chemistry provides efficient tools for studying them. However, accurate quantum chemistry calculation is costly for the simulation of large-size soot molecules and high-th...

  • Review
  • Open Access
17 Citations
5,654 Views
14 Pages

Cardiovascular Calcification as a Marker of Increased Cardiovascular Risk and a Surrogate for Subclinical Atherosclerosis: Role of Echocardiography

  • Andrea Faggiano,
  • Gloria Santangelo,
  • Stefano Carugo,
  • Gregg Pressman,
  • Eugenio Picano and
  • Pompilio Faggiano

13 April 2021

The risk prediction of future cardiovascular events is mainly based on conventional risk factor assessment by validated algorithms, such as the Framingham Risk Score, the Pooled Cohort Equations and the European SCORE Risk Charts. The identification...

  • Article
  • Open Access
25 Citations
5,242 Views
22 Pages

31 May 2019

The purpose of this study was to explore how a science, technology, engineering, and mathematics (STEM) project with mathematical modeling influenced student competencies regarding sustainability in a university classroom. We used mixed methods with...

  • Systematic Review
  • Open Access
1,136 Views
15 Pages

The Usefulness of 2-[18F]FDG PET or PET/CT in Extranodal Natural Killer/T-Cell Lymphoma: A Systematic Review and Meta-Analysis

  • Domenico Albano,
  • Carlo Rodella,
  • Alessandra Tucci,
  • Giorgio Treglia,
  • Francesco Bertagna,
  • Arturo Chiti and
  • Federico Fallanca

27 June 2025

Background/Objectives: Extranodal NK-/T-cell lymphoma (ENKTCL) is a rare and highly aggressive lymphoma with a bad prognosis. The aim of our analysis is to evaluate existing research on the potential usefulness of fluorine-18-fluorodeoxyglucose posit...

  • Article
  • Open Access
71 Citations
10,890 Views
19 Pages

Estimating Fractional Shrub Cover Using Simulated EnMAP Data: A Comparison of Three Machine Learning Regression Techniques

  • Marcel Schwieder,
  • Pedro J. Leitão,
  • Stefan Suess,
  • Cornelius Senf and
  • Patrick Hostert

22 April 2014

Anthropogenic interventions in natural and semi-natural ecosystems often lead to substantial changes in their functioning and may ultimately threaten ecosystem service provision. It is, therefore, necessary to monitor these changes in order to unders...

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