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164 Results Found

  • Article
  • Open Access
4 Citations
2,255 Views
22 Pages

31 May 2023

This research investigates the influence of the pre-existing defects within concrete taken from the in-service irrigation structure on the strain distribution. The X-ray Computed Tomography (CT) technique is employed to investigate the internal concr...

  • Article
  • Open Access
1 Citations
2,080 Views
10 Pages

Effects of Pre-Annealing on the Radiation Resistance of ZnO Nanorods

  • Tengfei Wu,
  • Aiji Wang,
  • Mingyu Wang,
  • Yinshu Wang,
  • Zilin Liu,
  • Yiwen Hu,
  • Zhenglong Wu and
  • Guangfu Wang

21 July 2022

Ion implantation is usually used for semiconductor doping and isolation, which creates defects in semiconductors. ZnO is a promising semiconductor and has a variety of applications, such as for use in transparent electronics, optoelectronics, chemica...

  • Review
  • Open Access
6 Citations
3,289 Views
18 Pages

15 February 2023

In many materials, impurities and imperfections play a critical role on the physical and chemical properties. In the present review, some examples of such materials are discussed. A bulk nanobubble (an ultrafine bubble) is stabilized against dissolut...

  • Article
  • Open Access
20 Citations
5,894 Views
13 Pages

15 February 2019

Molecular dynamics simulations are used to investigate the atomic effects of carbon (C) addition in Fe on the martensitic phase transformation in the presence of pre-existing defects such as stacking faults and twin boundaries. The pre-existing defec...

  • Article
  • Open Access
10 Citations
2,548 Views
19 Pages

Effect of Pre-Existing Micro-Defects on Cutting Force and Machined Surface Quality Involved in the Ball-End Milling Repairing of Flawed KDP Crystal Surfaces

  • Hongqin Lei,
  • Jian Cheng,
  • Dinghuai Yang,
  • Linjie Zhao,
  • Mingjun Chen,
  • Jinghe Wang,
  • Qi Liu,
  • Wenyu Ding and
  • Guang Chen

22 October 2022

When serving in extremely high-power laser conditions, KH2PO4 (KDP) surfaces are susceptible to incur laser damage points (also known as defects). Using micro-ball end milling cutters to repair and remove the pre-existing damage points on the flawed...

  • Article
  • Open Access
2 Citations
1,887 Views
16 Pages

Investigation of the Mechanical Behaviour of Lingulid Sandstone Emphasizing the Influence from Pre-Existing Structural Defects—Part 2: Dynamic Testing and Numerical Modelling

  • Pascal Forquin,
  • Mahdi Saadati,
  • Dominique Saletti,
  • Bratislav Lukic,
  • Federico Schiaffini,
  • Kenneth Weddfelt and
  • Per-Lennart Larsson

16 November 2022

In the present study, dynamic experiments are developed to investigate the induced damage modes when Lingulid sandstone is subjected to dynamic and impact loading. To do so, a series of spalling tests were carried out in order to investigate the mate...

  • Article
  • Open Access
4 Citations
1,786 Views
16 Pages

Investigation of the Mechanical Behaviour of Lingulid Sandstone Emphasising the Influence from Pre-Existing Structural Defects, Part 1: Model Identification Based on Static Experiments

  • Pascal Forquin,
  • Mahdi Saadati,
  • Dominique Saletti,
  • Bratislav Lukic,
  • Frederico Schiaffini,
  • Kenneth Weddfelt and
  • Per-Lennart Larsson

25 October 2022

A constitutive model able to describe both tensile damage and plastic deformation under confinement is a prerequisite to numerically simulate the behaviour of sandstone rock under an impact loading induced in a percussive drilling process. Therefore,...

  • Article
  • Open Access
18 Citations
5,577 Views
18 Pages

6 August 2022

The fatigue of engineered components involves more than the fatigue of metals as studied in laboratories. The miniscule laboratory test pieces cannot represent the pre-existing macroscopic crack defects in real engineering components. This brief stud...

  • Article
  • Open Access
3 Citations
1,725 Views
29 Pages

Dynamic Failure Characteristics of Sandstone Containing Different Angles of Pre-Existing Crack Defects

  • Hou-You Zhou,
  • Dian-Shu Liu,
  • Zheng-Hua Gao,
  • En-An Chi,
  • Jun-Ying Rao and
  • Tao Hu

24 May 2024

Fracture within the rock is one of the main factors leading to rock destabilization and has a significant effect on the stability of the project. In this study, sandstone is used as a research target, specimens with crack inclination angles of 0°...

  • Review
  • Open Access
8 Citations
6,110 Views
12 Pages

Folate Supplementation in Women with Pre-Existing Diabetes

  • Nayomi Perera,
  • Victoria L. Rudland,
  • David Simmons and
  • Sarah A. L. Price

13 April 2023

Folate supplementation in the periconceptual period is the standard of care for the prevention of neural tube defects. To support dietary folate intake, some countries have introduced mandatory folic acid fortification of food products. Robust eviden...

  • Article
  • Open Access
4 Citations
1,483 Views
15 Pages

Dynamic Deformation in Nuclear Graphite and Underlying Mechanisms

  • Melonie Thomas,
  • Hajin Oh,
  • Ryan Schoell,
  • Stephen House,
  • Miguel Crespillo,
  • Khalid Hattar,
  • William Windes and
  • Aman Haque

14 September 2024

Time-dependent deformation in nuclear graphite is influenced by the creation and migration of radiation-induced defects in the reactor environment. This study investigates the role of pre-existing defects such as point defect clusters and Mrozowski c...

  • Article
  • Open Access
5 Citations
2,761 Views
13 Pages

Structural Properties of He-Irradiated Zr/Nb Multilayer Investigated by Grazing Incidence X-ray Diffraction

  • Tao Wang,
  • Bingsheng Li,
  • Jun Li,
  • Haiyuan Wei,
  • Junjun Zhou,
  • Pan Dong,
  • Jie Li and
  • Vladimir Krsjak

4 March 2023

Zr/Nb nanoscale multilayers are regarded as one of the important candidate materials used in next-generation reactors. Understanding structural evolution induced by ion bombardment is crucial for the evaluation of lifetime performance. Magnetron sput...

  • Article
  • Open Access
11 Citations
4,189 Views
17 Pages

PMMA-Cement-PLIF Is Safe and Effective as a Single-Stage Posterior Procedure in Treating Pyogenic Erosive Lumbar Spondylodiscitis—A Single-Center Retrospective Study of 73 Cases

  • Moritz Caspar Deml,
  • Emmanuelle N. Cattaneo,
  • Sebastian Frederick Bigdon,
  • Hans-Jörg Sebald,
  • Sven Hoppe,
  • Paul Heini,
  • Lorin Michael Benneker and
  • Christoph Emanuel Albers

Background: Surgical treatment for erosive pyogenic spondylodiscitis of the lumbar spine is challenging as, following debridement of the intervertebral and bony abscess, a large and irregular defect is created. Sufficient defect reconstruction with c...

  • Review
  • Open Access
7 Citations
5,822 Views
19 Pages

Pre-Existing and Acquired Resistance to PARP Inhibitor-Induced Synthetic Lethality

  • Bac Viet Le,
  • Paulina Podszywałow-Bartnicka,
  • Katarzyna Piwocka and
  • Tomasz Skorski

24 November 2022

The advanced development of synthetic lethality has opened the doors for specific anti-cancer medications of personalized medicine and efficient therapies against cancers. One of the most popular approaches being investigated is targeting DNA repair...

  • Article
  • Open Access
3 Citations
3,822 Views
16 Pages

Zika Virus Infection in Pregnancy: Advanced Diagnostic Approaches in Dengue-Naive and Dengue-Experienced Pregnant Women and Possible Implication for Cross-Reactivity and Cross-Protection

  • Maurizio Zavattoni,
  • Francesca Rovida,
  • Elena Percivalle,
  • Irene Cassaniti,
  • Antonella Sarasini,
  • Alessia Arossa,
  • Beatrice Tassis,
  • Lina Bollani,
  • Giuseppina Lombardi and
  • Simona Orcesi
  • + 1 author

Zika virus (ZIKV) infection has been linked to congenital defects in fetuses and infants, as exemplified by the microcephaly epidemic in Brazil. Given the overlapping presence of Dengue virus (DENV) in the majority of ZIKV epidemic regions, advanced...

  • Article
  • Open Access
3 Citations
2,240 Views
10 Pages

Impact of Host Immune Status on Discordant Anti-SARS-CoV-2 Circulating B Cell Frequencies and Antibody Levels

  • Frédéric Coutant,
  • Jean-Jacques Pin,
  • Florence Morfin-Sherpa,
  • Tristan Ferry,
  • Stéphane Paul,
  • Bruno Pozzetto,
  • Myriam Normand and
  • Pierre Miossec

14 October 2021

Individuals with pre-existing chronic systemic low-grade inflammation are prone to develop severe COVID-19 and stronger anti-SARS-CoV-2 antibody responses. Whether this phenomenon reflects a differential expansion of antiviral B cells or a failure to...

  • Case Report
  • Open Access
1 Citations
287 Views
11 Pages

Staged Head and Neck Reconstruction: Heresy or a Reasoned Approach in a Select Group of Patients?

  • Mark L. Urken,
  • Quinn O’Malley,
  • Mykayla Sandler,
  • Monica H. Xing,
  • Edward Ansari,
  • Neil Mundi,
  • Daniel Buchbinder,
  • Eran Alon and
  • Devin Okay

Study Design: case series. Objective: The restoration of defects in a single procedure with microvascular free flap reconstruction has become a mainstay of head and neck surgery. Yet in patients with complex defects and pre-existing comorbid medical...

  • Article
  • Open Access
6 Citations
1,798 Views
16 Pages

27 June 2023

The generation of rock mass disasters in underground engineering essentially arises from the disruption of the original three-dimensional stress equilibrium of the rock mass caused by excavation and other activities, leading to the redistribution of...

  • Article
  • Open Access
1 Citations
1,958 Views
13 Pages

28 January 2024

In the present work, in situ electrochemical nanoindentation was utilized to investigate the hydrogen effect on the nanomechanical properties of tensile pre-strained nickel alloy (0%, 5% and 20%). The study reveals that hydrogen-induced hardening occ...

  • Article
  • Open Access
1,200 Views
15 Pages

Seroprevalence of Neutralizing Antibodies in Healthy Adults, in Mexico, Against Human and Simian Adenovirus Types

  • Raúl E. López,
  • Margarita Valdés Alemán,
  • Jesús M. Torres-Flores,
  • Yordanis Pérez-Llano,
  • David Alejandro Cabrera Gaytán,
  • Clara Esperanza Santacruz Tinoco,
  • Julio Elias Alvarado Yaah,
  • Yu Mei Anguiano Hernández,
  • Bernardo Martínez Miguel and
  • José Esteban Muñoz Medina
  • + 4 authors

29 August 2025

Replication-defective adenoviruses are widely used as vectors for vaccines, but their efficacy may be compromised by the prevalence of pre-existing neutralizing antibodies from natural infections or prior vaccination with adenovirus-based vaccines. T...

  • Article
  • Open Access
7 Citations
2,125 Views
11 Pages

Mechanical and Lattice Thermal Properties of Si-Ge Lateral Heterostructures

  • Liuhuan Zhao,
  • Lei Huang,
  • Ke Wang,
  • Weihua Mu,
  • Qiong Wu,
  • Zhen Ma and
  • Kai Ren

12 August 2024

Two-dimensional (2D) materials have drawn extensive attention due to their exceptional characteristics and potential uses in electronics and energy storage. This investigation employs simulations using molecular dynamics to examine the mechanical and...

  • Article
  • Open Access
9 Citations
3,018 Views
10 Pages

Electroforming-Free Bipolar Resistive Switching Memory Based on Magnesium Fluoride

  • Nayan C. Das,
  • Minjae Kim,
  • Jarnardhanan R. Rani,
  • Sung-Min Hong and
  • Jae-Hyung Jang

30 August 2021

Electroforming-free resistive switching random access memory (RRAM) devices employing magnesium fluoride (MgFx) as the resistive switching layer are reported. The electroforming-free MgFx based RRAM devices exhibit bipolar SET/RESET operational chara...

  • Article
  • Open Access
2 Citations
1,492 Views
20 Pages

29 January 2024

In this paper, the damage monitoring investigation based on the remote bonding fiber Bragg grating sensing is performed on the aerospace aluminum alloy thin-walled structure with prefabricated damage. Firstly, an ultrasonic excitation-fiber Bragg gra...

  • Feature Paper
  • Article
  • Open Access
4 Citations
6,359 Views
9 Pages

Positive Bias Temperature Instability in SiC-Based Power MOSFETs

  • Vladislav Volosov,
  • Santina Bevilacqua,
  • Laura Anoldo,
  • Giuseppe Tosto,
  • Enzo Fontana,
  • Alfio-lip Russo,
  • Claudio Fiegna,
  • Enrico Sangiorgi and
  • Andrea Natale Tallarico

30 June 2024

This paper investigates the threshold voltage shift (ΔVTH) induced by positive bias temperature instability (PBTI) in silicon carbide (SiC) power MOSFETs. By analyzing ΔVTH under various gate stress voltages (VGstress) at 150 °C, dist...

  • Article
  • Open Access
6 Citations
2,167 Views
13 Pages

22 May 2024

In additive manufacturing, such as Selective Laser Melting (SLM), identifying fabrication defects poses a significant challenge. Existing identification algorithms often struggle to meet the precision requirements for defect detection. To accurately...

  • Review
  • Open Access
6 Citations
5,363 Views
19 Pages

Pre-Existing Diabetes Mellitus, Hypertension and KidneyDisease as Risk Factors of Pre-Eclampsia: A Disease of Theories and Its Association with Genetic Polymorphism

  • Abdullah Salah Alanazi,
  • Francis Victor,
  • Kanwal Rehman,
  • Yusra Habib Khan,
  • Ismaeel Yunusa,
  • Abdulaziz Ibrahim Alzarea,
  • Muhammad Sajid Hamid Akash and
  • Tauqeer Hussain Mallhi

Pre-existing diabetes, hypertension and kidney disorders are prominent risk factors of pre-eclampsia (PE). It is a multifactorial pregnancy disorder associated with high blood pressure, proteinuria, and multiorgan failure, which develops after the 20...

  • Article
  • Open Access
2 Citations
2,240 Views
13 Pages

O2 Loaded Germanosilicate Optical Fibers: Experimental In Situ Investigation and Ab Initio Simulation Study of GLPC Evolution under Irradiation

  • Imene Reghioua,
  • Luigi Giacomazzi,
  • Antonino Alessi,
  • Blaz Winkler,
  • Layla Martin-Samos,
  • Sylvain Girard,
  • Diego Di Francesca,
  • Mattia Fanetti,
  • Nicolas Richard and
  • Philippe Paillet
  • + 5 authors

13 April 2022

In this work we present a combined experimental and ab initio simulation investigation concerning the Germanium Lone Pair Center (GLPC), its interaction with molecular oxygen (O2), and evolution under irradiation. First, O2 loading has been applied h...

  • Article
  • Open Access
26 Citations
3,841 Views
12 Pages

2 May 2019

Porosity defects are still a challenging issue in the fusion welding of molybdenum and its alloys due to the pre-existing interior defects associated with the powder metallurgy process. Fiber laser welding of end plug and cladding tube made of nanost...

  • Article
  • Open Access
16 Citations
4,206 Views
13 Pages

Investigation of Ion Irradiation Effects in Silicon and Graphite Produced by 23 MeV I Beam

  • Kristina Tomić Luketić,
  • Marko Karlušić,
  • Andreja Gajović,
  • Stjepko Fazinić,
  • Jacques H. O’Connell,
  • Borna Pielić,
  • Borna Radatović and
  • Marko Kralj

11 April 2021

Both silicon and graphite are radiation hard materials with respect to swift heavy ions like fission fragments and cosmic rays. Recrystallisation is considered to be the main mechanism of prompt damage anneal in these two materials, resulting in negl...

  • Article
  • Open Access
5 Citations
2,020 Views
13 Pages

7 February 2023

The creation of the natural ceiling rock of the coal seam is rife with fractures, holes, and other flaws. The angle of the defects has a significant influence on the mechanical characteristics and crack evolution of coal seam roof rock. Multi-scale n...

  • Article
  • Open Access
14 Citations
2,672 Views
15 Pages

Effect of Strain Rate, Temperature, Vacancy, and Microcracks on Mechanical Properties of 8-16-4 Graphyne

  • Qing Peng,
  • Zeyu Huang,
  • Gen Chen,
  • Yuqiang Zhang,
  • Xiaofan Zhang,
  • Xiao-Jia Chen and
  • Zhongwei Hu

21 March 2024

The 8-16-4 graphyne, a recently identified two-dimensional carbon allotrope, exhibits distinctive mechanical and electrical properties, making it a candidate material for flexible electronic applications. This study endeavors to enhance our comprehen...

  • Case Report
  • Open Access
4 Citations
3,534 Views
9 Pages

Human Anthrax in Dolj County, Romania—A Series of Three Cases

  • Florentina Dumitrescu,
  • Eugen Florin Georgescu,
  • Lucian Giubelan,
  • Vlad Pădureanu,
  • Andreea Cristina Stoian,
  • Viorica Dincă,
  • Milena Georgescu,
  • Livia Dragonu and
  • Daniela Marinescu

Bacillus anthracis is the causative agent of anthrax, primarily a disease of herbivorous animals, which can be accidentally transmitted to humans. Three cases of cutaneous human anthrax were recorded in August 2020 in Dolj county, Romania. These case...

  • Article
  • Open Access
1 Citations
2,328 Views
31 Pages

11 April 2025

Defect detection is still challenging to apply in reality because the goal of the entire classification assignment is to identify the exact type and location of every problem in an image. Since defect detection is a task that includes location and ca...

  • Article
  • Open Access
3 Citations
1,868 Views
16 Pages

14 July 2022

It is generally accepted that material inhomogeneity causes stress concentrations at the interface and thus reduces the overall strength of a composite. To overcome this reduction in strength, some groups experimented on coating the nanoinclusions wi...

  • Article
  • Open Access
6 Citations
2,899 Views
16 Pages

29 April 2024

In this research, we propose the use of infrared detection methods for identifying cracks in the tunnel lining of concrete structures. Through thermal simulation experiments on pre-existing cracks, we investigate the heat conduction patterns in crack...

  • Article
  • Open Access
34 Citations
4,885 Views
15 Pages

14 October 2020

Dislocation-based functionalities in inorganic ceramics and semiconductors are drawing increasing attention, contrasting the conventional belief that the majority of ceramic materials are brittle at room temperature. Understanding the dislocation beh...

  • Article
  • Open Access
41 Citations
5,987 Views
9 Pages

14 November 2017

The arc spraying process was used to prepare Fe-based amorphous/nanocrystalline coating. The cavitation erosion behaviors of FeNiCrBSiNbW coatings with different surface roughness levels were investigated in distilled water. The results showed that F...

  • Article
  • Open Access
21 Citations
3,459 Views
19 Pages

On the Statistical Size Effect of Cast Aluminium

  • Roman Aigner,
  • Sebastian Pomberger,
  • Martin Leitner and
  • Michael Stoschka

14 May 2019

Manufacturing process based imperfections can reduce the theoretical fatigue strength since they can be considered as pre-existent microcracks. The statistical distribution of fatigue fracture initiating defect sizes also varies with the highly-stres...

  • Article
  • Open Access
3 Citations
2,202 Views
9 Pages

28 May 2023

Background: A 24 h Holter study in children after transcatheter secundum ASD (ASD II) closure was conducted to detect the prevalence of defects and/or device-related late atrial arrhythmias (LAAs). ASD II closure with an Amplatzer septal occluder (AS...

  • Article
  • Open Access
29 Citations
3,915 Views
12 Pages

A Systematic Histopathologic Evaluation of Type-A Aortic Dissections Implies a Uniform Multiple-Hit Causation

  • Nimrat Grewal,
  • Bart J. J. Velders,
  • Adriana C. Gittenberger-de Groot,
  • Robert Poelmann,
  • Robert J. M. Klautz,
  • Thomas J. Van Brakel and
  • Jan H. N. Lindeman

(1) Background: The pathophysiologic basis of an acute type A aortic dissection (TAAD) is largely unknown. In an effort to evaluate vessel wall defects, we systematically studied aortic specimens in TAAD patients. (2) Methods: Ascending aortic wall s...

  • Article
  • Open Access
2 Citations
2,557 Views
8 Pages

1 December 2020

The instability of transistor characteristics caused by charge trapping under positive bias temperature (PBT) stress in In0.7Ga0.3As metal oxide semiconductor field-effect transistors (MOSFETs) with single-layer Al2O3 and bi-layer Al2O3/HfO2 gate sta...

  • Article
  • Open Access
4 Citations
2,870 Views
23 Pages

10 March 2023

A synergistic set of NDT techniques, including I–V analysis, UVF imaging, IR thermography, and EL imaging, supports a diagnostics methodology developed in this work to qualitatively and quantitatively identify a wide range of PV defects. The me...

  • Article
  • Open Access
743 Views
20 Pages

26 June 2025

FeCrAl alloys have garnered considerable attention as candidate cladding materials for light water reactors due to their promising mechanical stability and irradiation resistance. However, the response characteristics of these alloys to irradiation a...

  • Review
  • Open Access
54 Citations
7,546 Views
18 Pages

Review of Radiation-Induced Effects on β-Ga2O3 Materials and Devices

  • Nethala Manikanthababu,
  • Hardhyan Sheoran,
  • Pradeep Siddham and
  • Rajendra Singh

21 July 2022

β-Ga2O3 has become an ultimate choice of emerging new-generation material for its wide range of compelling applications in power electronics. In this review, we have explored the available radiations in the atmosphere and the effects of radiatio...

  • Article
  • Open Access
10 Citations
2,479 Views
13 Pages

Real-Time Observation of Nanoscale Kink Band Mediated Plasticity in Ion-Irradiated Graphite: An In Situ TEM Study

  • Melonie P. Thomas,
  • Ryan Schoell,
  • Nahid Sultan Al-Mamun,
  • Winson Kuo,
  • John Watt,
  • William Windes,
  • Khalid Hattar and
  • Aman Haque

15 February 2024

Graphite IG-110 is a synthetic polycrystalline material used as a neutron moderator in reactors. Graphite is inherently brittle and is known to exhibit a further increase in brittleness due to radiation damage at room temperature. To understand the i...

  • Review
  • Open Access
10 Citations
8,707 Views
20 Pages

Over the past several decades, viral vector-based vaccines have emerged as some of the most versatile and potent platforms in modern vaccinology. Their capacity to deliver genetic material encoding target antigens directly into host cells enables str...

  • Review
  • Open Access
58 Citations
5,922 Views
30 Pages

9 April 2021

The attractive strain burst phenomenon, so-called “pop-in”, during indentation-induced deformation at a very small scale is discussed as a fundamental deformation behavior in various materials. The nanoindentation technique can probe a mechanical res...

  • Article
  • Open Access
7 Citations
1,362 Views
5 Pages

Management of Acute Osteomyelitis: A Ten-Year Experience

  • Caitlin Helm,
  • Emily Huschart,
  • Rajat Kaul,
  • Samina Bhumbra,
  • R. Alexander Blackwood and
  • Deepa Mukundan

29 September 2016

Osteomyelitis is an infection of the bone; proper management requires prolonged antibiotic treatment. Controversy exists as to when a patient should transition from intravenous to oral antibiotics. However, due to the high bioavailability of some ora...

  • Article
  • Open Access
610 Views
21 Pages

21 July 2025

Concrete is extensively utilized in infrastructure projects. However, issues like construction quality and external loads can lead to the formation of thin-plate-like voids with considerable aspect ratios, posing serious safety risks and highlighting...

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