Cooperative binding pervades Nature. This review discusses the use of isothermal titration calorimetry (ITC) in the identification and characterisation of cooperativity in biological interactions. ITC has broad scope in the analysis of cooperativity...
The recognition of specific DNA sequences in processes such as transcription is associated with a cooperative binding of proteins. Some transcription regulation mechanisms involve additional proteins that can influence the binding cooperativity by ac...
(1) Background: To enhance the walking-assistance efficiencies of exoskeletons, this paper proposed the biomechanical-based cooperativity model based on a passive exoskeleton prototype to fill the technical gap in exoskeleton design regarding the tor...
A full quantitative description of the swelling of smart microgels is still problematic in many cases. The original approach of Flory and Huggins for the monomer–solvent interaction parameter
Sperm have thin structures known as flagella whose motion must be regulated in order to reach the egg for fertilization. Large numbers of sperm are typically needed in this process and some species have sperm that exhibit collective or aggregate moti...
p53 is a tumor suppressor that is mutated in half of all cancers. The high clinical relevance has made p53 a model transcription factor for delineating general mechanisms of transcriptional regulation. p53 forms tetramers that bind DNA in a highly co...
The hydrogen bond (H-bond) cooperativity in the β-sheet of GB3 is investigated by a NMR hydrogen/deuterium (H/D) exchange method. It is shown that the weakening of one backbone N–H…O=C H-bond between two β-strands, β1 and...
The objective of this paper is to find new dynamic perspectives in a well-known two dimensional nonlinear system which is a modification of the phosphofructo kinase model by incorporating recycling of the product,
In a series of Hofmann-like spin crossover complexes, two new compounds, {Fe(3-F-4-Methyl-py)2[Au(CN)2]2} (1) and {Fe(3-Methyl-py)2[Au(CN)2]2} (2) (py = pyridine) are described. The series maintains a uniform 2-dimentional (2-D) layer structure of {F...
A coinage-metal bond has been predicted and characterized in the complexes of [1.1.1]propellane (P) and M2/MCl/MCH3 (M = Cu, Ag, and Au). The interaction energy varies between −16 and −47 kcal/mol, indicating that the bridgehead carbon at...
Uranyl–protein interactions participate in uranyl trafficking or toxicity to cells. In addition to their qualitative identification, thermodynamic data are needed to predict predominant mechanisms that they mediate in vivo. We previously showed...
Human NQO1 [NAD(H):quinone oxidoreductase 1] is a multi-functional and stress-inducible dimeric protein involved in the antioxidant defense, the activation of cancer prodrugs and the stabilization of oncosuppressors. Despite its roles in human diseas...
The incorporation of disease-relevant targets into ternary complexes in a compound-dependent manner by utilizing an assisting chaperone has become a common modality as far as bifunctional ternary complex-forming compounds are concerned. In contrast,...
Allostery is a property of biological macromolecules featuring cooperative ligand binding and regulation of ligand affinity by effectors. The definition was introduced by Monod and Jacob in 1963, and formally developed as the “concerted model&r...
With the advancement of farmer professional cooperatives in China, the prevalence of the “empty shell” phenomenon has posed a significant challenge to the health and sustainability of these cooperatives. Utilizing data from 1570 such coop...
Immunological synapse (IS) formation is a key event during antigen recognition by T cells. Recent experimental evidence suggests that the affinity between T cell receptors (TCRs) and antigen is actively modulated during the early steps of TCR signali...
Similar to the number of agricultural cooperatives in the European Union, the number of German wine cooperatives is decreasing. The main purpose of the wine cooperatives is to support the member businesses with the highest possible payouts for their...
The paper deals with the topic of the cooperation management in the Slovak business environment. We closely investigated the cooperation relations among the companies from 2012 to 2015. The major findings related to problems which impede effective co...
Despite popular misconceptions, cooperatives present a very successful organizational form worldwide. A recent study found that in the U.S., for example, 134 agricultural cooperatives celebrated their 100th anniversary in 2014. This observation on co...
In this paper we describe cooperation and social dilemmas in multiagent systems, with an analogy applied to road traffic. Cooperative human drivers, based on their perception of trust and fairness, find efficient solutions for such dilemmas. In the d...
The static share-a-ride problem (SARP) consists of handling people and parcels in an integrated way through the same vehicle, which provides a shared trip between an origin and a destination, in response to requests received in advance. When multiple...
The aim of this study was to identify the preferences of final purchasers regarding the environment of cooperation with offerors and the benefits of cooperation, as well as to identify dependencies between two groups of preferences, taking into accou...
Farmer professional cooperatives are essential in promoting China’s rural revitalization. However, the widespread occurrence of “empty shell” cooperatives, which are characterized by operational stagnation and human resource depleti...
This paper proposes a cooperative medium access control (MAC) protocol for underwater wireless sensor networks (UWSNs) named UCMAC, which fundamentally benefits from cooperative communication. In UCMAC, a source identifies cooperators and provides it...
Non-cooperative games in normal form are specified by a player set, sets of player strategies, and payoff functions. Cooperative games, meanwhile, are specified by a player set and a worth function that maps coalitions of players to payoffs they can...
In this paper, two-to-one energy and spectrum dual-cooperation (ESDC) is investigated for cognitive cooperation networks. Specifically, the energy and spectrum of two primary users (PUs) are both transferred or authorized to one multi-antenna seconda...
To address the negative impact of large-scale disorderly grid connection of EVs on the stable operation of the power grid, a cooperative game cooperative control strategy for EVs based on tariff leverage is proposed, taking the grid-side and user-sid...
The paper deals with the topic of the cooperation ecosystem in the Žilina higher self-government region (HSGR). The results are mainly from our research about cooperation in the region. According to the research results, the most developed areas of t...
A systematic approach to teamwork is important for clarifying the behavior of actors in a cooperative environment. The cooperative game as system steps is most often shown in teamwork. The aim of this article is to present the results of this researc...
This article explores, quantitatively and qualitatively, how gender-neutral groups of pre-service teachers in homogenous and heterogeneous cooperative learning prioritize individual responsibility, promotive interaction, and positive interdependence....
Farming cooperatives are organisations fundamentally based on social capital. However, the neoliberal and globalisation turn in the food system have led to the economisation of agricultural cooperatives as their main objective and criteria for evalua...
This research aims to determine the demographic and economic factors affecting agriculture cooperation activity in Kosovo. Primary data was collected from 249 farmers in Kosovo through structured questionnaires using the random sampling technique. Th...
In some satellite Internet of Things (IoT) devices with terrain shielding, the qualities of the direct source-destination (S-D) channel are poor, requiring cooperative communications with multi-relays to be employed. In order to solve error propagati...
Tourism cooperation is an essential element for tourism development in China-ASEAN countries and has made a significant economic contribution to destinations. This study investigates the structure of tourism cooperation in China-ASEAN relations and i...
Agricultural cooperatives are essential in mitigating climate change and food insecurity through the promotion of sustainable agricultural practices and the conservation of biodiversity. However, weaknesses in governance, economic restrictions, marke...
The purpose of this article is to determine final purchasers’ needs satisfied due to cooperation with offerors and the dependencies between these needs and previous behaviors and attitudes toward this cooperation. The results of the world liter...
The exploration of the ionic liquids’ mechanism of action on nucleobase’s structure and properties is still limited. In this work, the binding model of the 1-alkyl-3-methylimidazolium bromide ([Cnmim]Br, n = 2, 4, 6, 8, 10) ionic liquids...
The aim of the present study is to examine the sustainability reports of cooperatives, which may play an important role in achieving the sustainable development goals and help to identify which economic, environmental, and social sustainability indic...
Space non-cooperative target recognition is crucial for on-orbit servicing. Multi-satellite cooperation has great potential for broadening the observation scope and enhancing identification efficiency. However, there is currently a lack of research o...
This paper reports on the discovery of a novel three-membrane channel unit exhibiting very steep voltage dependence and strong cooperative behavior. It was reconstituted into planar phospholipid membranes formed by the monolayer method and studied un...
The proliferation of mobile devices has driven significant growth in adaptive mobile applications (AMAs) that dynamically adjust their behavior based on contextual changes. While existing research has extensively studied individual adaptive systems,...
The Moroccan agricultural cooperative sector is a key player in self-employment and income generation through territorial anchoring. The government’s “MOURAFAKA” program offers support for newly created cooperatives, including strat...
The safety impacts of cooperative platooning in mixed traffic consisting of human-driven, connected, and connected–automated vehicles were evaluated. The cooperative platooning, in the case of the mixed traffic control algorithm evaluated here,...
The aim of this article is to determine the extent to which (directly or indirectly) the papal teachings apply to cooperatives as tools for solving social, economic and environmental problems, which were defined by Sustainable Development Goals (SDGs...
Since 2013, the Chinese central government has pushed cooperation on environmental governance in Urban Agglomerations (UAs). In some of these UAs, cities have previously been developing environmental governance activities autonomously, in the absence...
Creation of a sustainable agricultural sector involves boosting the cooperation activities as these contribute to the societal and economic development of the farms, farmers and rural societies. This paper contributes to the literature on the analysi...
Cooperative attention provides a new method to study how epidemic diseases are spread. It is derived from the social data with the help of survey data. Cooperative attention enables the detection possible anomalies in an event by formulating the spre...
Cooperatives cover a large part of the agricultural sectors and have substantial market shares in agri-food supply chains in the EU Western countries. They account for approximately half of agricultural trade in the EU. By contrast, in the EU Western...
Persistent regional imbalances and widening urban–rural income gaps hinder progress toward Sustainable Development Goal 10 (Reduced Inequalities). In response, China has implemented a typical regional cooperation program—East–West C...
Millennials represent the most important group among the working age population. Destined to be the leaders of the future, their professional and personal profiles differ considerably from previous generations. Despite being considered as the most su...
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