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123 Results Found

  • Article
  • Open Access
18 Citations
3,677 Views
20 Pages

The SAUR (small auxin-up RNA) gene family is the biggest family of early auxin response genes in higher plants and has been associated with the control of a variety of biological processes. Although SAUR genes had been identified in several genomes,...

  • Article
  • Open Access
24 Citations
5,733 Views
11 Pages

Identification and Expression of SAUR Genes in the CAM Plant Agave

  • Gang Deng,
  • Xing Huang,
  • Li Xie,
  • Shibei Tan,
  • Thomas Gbokie,
  • Yaning Bao,
  • Zhouli Xie and
  • Kexian Yi

23 July 2019

Agave species are important crassulacean acid metabolism (CAM) plants and widely cultivated in tropical areas for producing tequila spirit and fiber. The hybrid H11648 of Agave ((A. amaniensis × A. angustifolia) × A. amaniensis) is the ma...

  • Article
  • Open Access
23 Citations
3,709 Views
18 Pages

14 November 2022

The wax gourd (Benincasa hispida) is an important vegetable crop whose fruits contain nutrients and metabolites. Small auxin upregulated RNA (SAUR) genes constitute the largest early auxin-responsive gene family and regulate various biological proces...

  • Article
  • Open Access
6 Citations
2,388 Views
15 Pages

Analysis of the Small Auxin-Up RNA (SAUR) Genes Regulating Root Growth Angle (RGA) in Apple

  • Yufei Zhou,
  • Qingqing Lan,
  • Wenhan Yu,
  • Yuwen Zhou,
  • Shuya Ma,
  • Zeyang Bao,
  • Xu Li and
  • Caixia Zheng

15 November 2022

Small auxin upregulated RNAs (SAURs) are primary auxin response genes; the function of regulating root growth angle (RGA) is unclear in the apple rootstock. We firstly identified 96 MdSAUR genes families from new apple genome GDDH13 using the reseque...

  • Article
  • Open Access
9 Citations
2,753 Views
15 Pages

Genome-Wide Analysis of the SAUR Gene Family and Its Expression Profiles in Response to Salt Stress in Santalum album

  • Qing Zhu,
  • Haoyue Zheng,
  • Xu Hu,
  • Yi Liu,
  • Xinyi Zheng,
  • Libei Li and
  • Minqiang Tang

7 May 2024

The SAUR (small auxin-up RNA) family constitutes a category of genes that promptly respond to the hormone auxin and play a pivotal role in diverse biological processes encompassing plant growth and the response to abiotic stress. Santalum album L., a...

  • Article
  • Open Access
3 Citations
1,172 Views
18 Pages

The SAUR (Small Auxin-Upregulated RNA) family members are important early auxin responsive genes in plants, playing a key regulatory role in the auxin metabolism, signal transduction, plant organ development, and abiotic stress response. Auxin signal...

  • Article
  • Open Access
25 Citations
4,017 Views
18 Pages

Grape Small Auxin Upregulated RNA (SAUR) 041 Is a Candidate Regulator of Berry Size in Grape

  • Ming Li,
  • Rui Chen,
  • Hong Gu,
  • Dawei Cheng,
  • Xizhi Guo,
  • Caiyun Shi,
  • Lan Li,
  • Guoyi Xu,
  • Shicao Gu and
  • Jinyong Chen
  • + 1 author

30 October 2021

Grape (Vitis vinifera) is an important horticultural crop that can be used to make juice and wine. However, the small size of the berry limits its yield. Cultivating larger berry varieties can be an effective way to solve this problem. As the largest...

  • Article
  • Open Access
20 Citations
3,426 Views
15 Pages

Auxin serves as an essential regulator of the expression of many different genes in plants, thereby regulating growth and development. The specific functional roles of members of the SAUR (small auxin-up RNA) auxin early response gene family in the d...

  • Article
  • Open Access
7 Citations
3,289 Views
21 Pages

Genome-Wide Analysis of SAUR Gene Family Identifies a Candidate Associated with Fruit Size in Loquat (Eriobotrya japonica Lindl.)

  • Ze Peng,
  • Wenxiang Li,
  • Xiaoqing Gan,
  • Chongbin Zhao,
  • Dev Paudel,
  • Wenbing Su,
  • Juan Lv,
  • Shunquan Lin,
  • Zongli Liu and
  • Xianghui Yang

31 October 2022

Fruit size is an important fruit quality trait that influences the production and commodity values of loquats (Eriobotrya japonica Lindl.). The Small Auxin Upregulated RNA (SAUR) gene family has proven to play a vital role in the fruit development of...

  • Article
  • Open Access
6 Citations
2,636 Views
15 Pages

Genome-Wide Identification of TaSAUR Gene Family Members in Hexaploid Wheat and Functional Characterization of TaSAUR66-5B in Improving Nitrogen Use Efficiency

  • Weizeng Lv,
  • Xue He,
  • Haojuan Guo,
  • Haibin Lan,
  • Yanqing Jiao,
  • Le Li,
  • Yanhao Lian,
  • Zhiqiang Wang,
  • Zeyu Xin and
  • Tongbao Lin
  • + 1 author

Excessive input of nitrogen fertilizer not only causes a great waste of resources but brings about a series of ecological and environmental problems. Although Small Auxin Up-regulated RNAs (SAURs) participate in diverse biological processes, the...

  • Article
  • Open Access
2 Citations
2,381 Views
13 Pages

A Modeling Approach to Studying the Influence of Grafting on the Anatomical Features and SAUR Gene Expression in Watermelons

  • Rita Márkus,
  • Marianna Kocsis,
  • Ágnes Farkas,
  • Dávid U. Nagy,
  • Paul Helfrich,
  • Damir Kutyáncsánin,
  • Gergely Nyitray,
  • Szilvia Czigle and
  • Szilvia Stranczinger

7 July 2024

Grafting alters the genetic and anatomical features of plants. Although grafting has been widely applied in plant propagation, the underlying processes that govern the effects of the procedure are not fully understood. Samples were collected to study...

  • Article
  • Open Access
2 Citations
1,368 Views
17 Pages

9 May 2025

The small-molecule compound fipexide (FPX) has been shown to promote callus formation in several plants, but its effects on forage crops remain unexplored, and its molecular mechanism is not yet fully understood. In this study, we evaluated FPX-induc...

  • Article
  • Open Access
21 Citations
2,685 Views
14 Pages

The Small Auxin-Up RNA SAUR10 Is Involved in the Promotion of Seedling Growth in Rice

  • Xiaolong Huang,
  • Zhanhua Lu,
  • Lisheng Zhai,
  • Na Li and
  • Huiqing Yan

17 November 2023

Small auxin-up-regulated RNAs (SAURs) are genes rapidly activated in response to auxin hormones, significantly affecting plant growth and development. However, there is limited information available about the specific functions of SAURs in rice due t...

  • Article
  • Open Access
4 Citations
3,448 Views
19 Pages

PpSAUR43, an Auxin-Responsive Gene, Is Involved in the Post-Ripening and Softening of Peaches

  • Jiahui Wang,
  • Weijing Su,
  • Kun Liu,
  • Ze Xu,
  • Kamran Shah,
  • Juanjuan Ma,
  • Dong Zhang,
  • Yanan Hu and
  • Caiping Zhao

Auxin’s role in the post-ripening of peaches is widely recognized as important. However, little is known about the processes by which auxin regulates fruit post-ripening. As one of the early auxin-responsive genes, it is critical to understand...

  • Article
  • Open Access
2 Citations
1,049 Views
18 Pages

PtrSAUR32 Interacts with PtrPP2C.Ds to Regulate Root Growth in Citrus

  • Xiaoli Wang,
  • Xiaoya Li,
  • Saihang Zheng,
  • Fusheng Wang,
  • Shiping Zhu and
  • Xiaochun Zhao

22 May 2025

Small auxin-up-regulated RNA (SAUR) genes are involved in the regulation of dynamic and adaptive growth in higher plants. However, their function and mode of action in citrus root growth are still unknown. Here, we demonstrate that in Poncirus trifol...

  • Article
  • Open Access
11 Citations
2,711 Views
13 Pages

A Small Auxin-Up RNA Gene, IbSAUR36, Regulates Adventitious Root Development in Transgenic Sweet Potato

  • Yuanyuan Zhou,
  • Aixian Li,
  • Taifeng Du,
  • Zhen Qin,
  • Liming Zhang,
  • Qingmei Wang,
  • Zongyun Li and
  • Fuyun Hou

10 June 2024

Small auxin-upregulated RNAs (SAURs), as the largest family of early auxin-responsive genes, play important roles in plant growth and development processes, such as auxin signaling and transport, hypocotyl development, and tolerance to environmental...

  • Article
  • Open Access
8 Citations
2,622 Views
24 Pages

Evidence That PbrSAUR72 Contributes to Iron Deficiency Tolerance in Pears by Facilitating Iron Absorption

  • Guoling Guo,
  • Tao Yu,
  • Haiyan Zhang,
  • Meng Chen,
  • Weiyu Dong,
  • Shuqin Zhang,
  • Xiaomei Tang,
  • Lun Liu,
  • Wei Heng and
  • Bing Jia
  • + 1 author

30 May 2023

Iron is an essential trace element for plants; however, low bioactive Fe in soil continuously places plants in an Fe-deficient environment, triggering oxidative damage. To cope with this, plants make a series of alterations to increase Fe acquisition...

  • Article
  • Open Access
671 Views
15 Pages

PtrIAA12-PtrARF8 Complex Regulates the Expression of PtrSAUR17 to Control the Growth of Roots in Poncirus trifoliata

  • Xiaoli Wang,
  • Manman Zhang,
  • Xiaoya Li,
  • Saihang Zheng,
  • Fusheng Wang,
  • Shiping Zhu and
  • Xiaochun Zhao

16 September 2025

The root system is an important determinant affecting the growth, adaptivity and stress resistance of citrus plants. Currently, the genetic regulatory network underlying root growth and development in citrus remains largely unknown. We report that a...

  • Article
  • Open Access
938 Views
27 Pages

GmSAUR46b Integrates Light Signals to Regulate Leaf Midrib Thickness and Stem Trichome Density in Soybean

  • Xiao Li,
  • Bei Liu,
  • Yunhua Yang,
  • Han Gou,
  • Huan Du,
  • Yuhao Chen,
  • Huakun Yu,
  • Jinming Zhao and
  • Fengjie Yuan

20 September 2025

Soybean (Glycine max (L.) Merr.) is a vital crop for the global supply of protein and oil, with its growth and development being regulated by genetic, hormonal, and environmental factors, particularly light and hormone signaling. The Small Auxin-Up R...

  • Article
  • Open Access
2 Citations
1,245 Views
13 Pages

SMALL AUXIN UP-REGULATED RNA (SAURs) genes are acknowledged as auxin-responsive genes that play crucial roles in modulating adaptive growth under abiotic stress conditions. Low temperatures constitute a primary limiting factor that significantly impa...

  • Article
  • Open Access
2 Citations
2,620 Views
14 Pages

18 October 2022

The plant hormone ABA regulates various physiological processes, such as promoting stomatal closure and inhibiting hypocotyl elongation by mediating de-phosphorylation of H+-ATPase. However, the mechanism acting on ABA-induced de-phosphorylation of H...

  • Article
  • Open Access
9 Citations
2,903 Views
17 Pages

Functional Analysis of Aux/IAAs and SAURs on Shoot Growth of Lagerstroemia indica through Virus-Induced Gene Silencing (VIGS)

  • Lu Feng,
  • Xiaohan Liang,
  • Yang Zhou,
  • Ye Zhang,
  • Jieru Liu,
  • Ming Cai,
  • Jia Wang,
  • Tangren Cheng,
  • Qixiang Zhang and
  • Huitang Pan

30 November 2020

The plant hormone auxin plays an important role in cell division and the elongation of shoots to affect the plant architecture, which has a great impact on the plant yield, fruit quality and ornamental value; however, the regulatory mechanism of auxi...

  • Article
  • Open Access
26 Citations
4,815 Views
22 Pages

20 September 2019

Auxin is well known to regulate growth and development processes. Auxin early response genes serve as a critical component of auxin signaling and mediate auxin regulation of diverse physiological processes. In the present study, a genome-wide identif...

  • Article
  • Open Access
18 Citations
4,004 Views
21 Pages

A Long Noncoding RNA Derived from lncRNA–mRNA Networks Modulates Seed Vigor

  • Qiaoli Gao,
  • Jinzhao Liu,
  • Huibin Weng,
  • Xi Yuan,
  • Wuming Xiao and
  • Hui Wang

22 August 2022

The discovery of long noncoding RNAs (lncRNAs) has filled a great gap in our understanding of posttranscriptional gene regulation in a variety of biological processes related to plant stress responses. However, systematic analyses of the lncRNAs expr...

  • Article
  • Open Access
5 Citations
2,057 Views
11 Pages

The Small Auxin-Up RNA 50 (SAUR50) Gene from Ammopiptanthus nanus Negatively Regulates Drought Tolerance

  • Yuanyuan Zhang,
  • Qi Li,
  • Mengyang Jiang,
  • Hui Tian,
  • Muhammad Hayder Bin Khalid,
  • Yingge Wang and
  • Haoqiang Yu

7 September 2024

Drought stress is a primary abiotic stress that causes significant losses to forestry and agricultural production. Therefore, exploring drought-responsive genes and their regulatory mechanism is crucial for plant molecular breeding for forestry and a...

  • Article
  • Open Access
43 Citations
5,690 Views
17 Pages

The Rice Small Auxin-Up RNA Gene OsSAUR33 Regulates Seed Vigor via Sugar Pathway during Early Seed Germination

  • Jia Zhao,
  • Wenjun Li,
  • Shan Sun,
  • Liling Peng,
  • Zhibo Huang,
  • Yongqi He and
  • Zhoufei Wang

4 February 2021

Seed vigor affects seed germination and seedling emergence, and therefore is an important agronomic trait in rice. Small auxin-up RNAs (SAURs) function in a range of developmental processes, but their role in seed vigor remains unclear. Here, we obse...

  • Article
  • Open Access
26 Citations
5,017 Views
19 Pages

The Potential Role of Auxin and Abscisic Acid Balance and FtARF2 in the Final Size Determination of Tartary Buckwheat Fruit

  • Moyang Liu,
  • Zhaotang Ma,
  • Tianrun Zheng,
  • Jing Wang,
  • Li Huang,
  • Wenjun Sun,
  • Yanjun Zhang,
  • Weiqiong Jin,
  • Junyi Zhan and
  • Gang Zhao
  • + 7 authors

13 September 2018

Tartary buckwheat is a type of cultivated medicinal and edible crop with good economic and nutritional value. Knowledge of the final fruit size of buckwheat is critical to its yield increase. In this study, the fruit development of two species of Tar...

  • Article
  • Open Access
1,744 Views
15 Pages

17 June 2024

Canola is the largest self-produced vegetable oil source in China, although excessive levels of cadmium, lead, and arsenic seriously affect its yield. Therefore, developing methods to identify canola materials with good heavy metal tolerance is a hot...

  • Article
  • Open Access
6 Citations
3,991 Views
21 Pages

Complete Genome Sequence and Analysis of a ST573 Multidrug-Resistant Methicillin-Resistant Staphylococcus aureus SauR3 Clinical Isolate from Terengganu, Malaysia

  • Esra’a I. Al-Trad,
  • Ainal Mardziah Che Hamzah,
  • Suat Moi Puah,
  • Kek Heng Chua,
  • Muhamad Zarul Hanifah,
  • Qasim Ayub,
  • Prasit Palittapongarnpim,
  • Stephen M. Kwong,
  • Ching Hoong Chew and
  • Chew Chieng Yeo

Methicillin-resistant Staphylococcus aureus (MRSA) is a World Health Organization-listed priority pathogen. Scarce genomic data are available for MRSA isolates from Malaysia. Here, we present the complete genome sequence of a multidrug-resistant MRSA...

  • Article
  • Open Access
17 Citations
6,985 Views
19 Pages

Multidrug-Resistant Methicillin-Resistant Staphylococcus aureus Associated with Hospitalized Newborn Infants

  • Ching Hoong Chew,
  • Chew Chieng Yeo,
  • Ainal Mardziah Che Hamzah,
  • Esra’a I. Al-Trad,
  • Sherry Usun Jones,
  • Kek Heng Chua and
  • Suat Moi Puah

Multidrug resistance (MDR) is a significant challenge in healthcare management, and addressing it requires a comprehensive approach. In this study, we employed a combination of phenotypic and genotypic approaches, along with whole genome sequencing (...

  • Article
  • Open Access
19 Citations
3,516 Views
10 Pages

Tocilizumab for the Treatment of Familial Mediterranean Fever—A Randomized, Double-Blind, Placebo-Controlled Phase II Study

  • Joerg C. Henes,
  • Sebastian Saur,
  • David M. Kofler,
  • Claudia Kedor,
  • Christoph Meisner,
  • Marion Schuett,
  • Martin Krusche,
  • Ina Koetter,
  • Theodoros Xenitidis and
  • Eugen Feist
  • + 1 author

13 September 2022

Background: The purpose of this trial was to evaluate the effectiveness and safety of the IL-6 receptor antibody Tocilizumab (TCZ) in the treatment of Familial Mediterranean Fever (FMF). Methods: This was a randomized, double-blinded, placebo-control...

  • Article
  • Open Access
2 Citations
3,025 Views
19 Pages

The Supratrochlear Artery Sign—A New Piece in the Puzzle of Cerebral Vasospasm

  • Cindy Richter,
  • Robert Werdehausen,
  • Jennifer Jentzsch,
  • Dirk Lindner,
  • Thilo Gerhards,
  • Torsten Hantel,
  • Khaled Gaber,
  • Stefan Schob,
  • Dorothee Saur and
  • Dirk Halama
  • + 3 authors

9 September 2022

Background: Cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) has been extensively investigated, but the impact of collateralization remains unclear. We investigated the predictive value of collateral activation for delayed cerebral ischem...

  • Article
  • Open Access
16 Citations
5,964 Views
44 Pages

Holistic Approach to Process Design and Scale-Up for Itaconic Acid Production from Crude Substrates

  • Katharina Maria Saur,
  • Robert Kiefel,
  • Paul-Joachim Niehoff,
  • Jordy Hofstede,
  • Philipp Ernst,
  • Johannes Brockkötter,
  • Jochem Gätgens,
  • Jörn Viell,
  • Stephan Noack and
  • Andreas Jupke
  • + 2 authors

Bio-based bulk chemicals such as carboxylic acids continue to struggle to compete with their fossil counterparts on an economic basis. One possibility to improve the economic feasibility is the use of crude substrates in biorefineries. However, impur...

  • Article
  • Open Access
6 Citations
2,450 Views
15 Pages

Fate of Microplastic Pollution Along the Water and Sludge Lines in Municipal Wastewater Treatment Plants

  • Thibaut Saur,
  • Florian Paillet,
  • Samuel Robert,
  • Jean-Claude Alibar,
  • Jean-François Loret and
  • Bruno Barillon

Microplastics have emerged as a global environmental concern due to their widespread presence and potential effects on ecosystems. Wastewater treatment plants (WWTPs) play a critical role in mitigating the release of microplastics into the environmen...

  • Article
  • Open Access
2 Citations
1,973 Views
21 Pages

Information Model for Pharmaceutical Smart Factory Equipment Design

  • Roland Wölfle,
  • Irina Saur-Amaral and
  • Leonor Teixeira

Pharmaceutical production typically focuses on individual drug types for each production line, which limits flexibility. However, the emergence of Industry 4.0 technologies presents new opportunities for more adaptable and customized manufacturing pr...

  • Article
  • Open Access
1 Citations
1,521 Views
11 Pages

Final Results from U.S. FCEV Learning Demonstration

  • Keith Wipke,
  • Sam Sprik,
  • Jennifer Kurtz,
  • Todd Ramsden,
  • Chris Ainscough and
  • Genevieve Saur

The “Controlled Hydrogen Fleet and Infrastructure Demonstration and Validation Project,” also known as the National Fuel Cell Electric Vehicle Learning Demonstration, is a U.S. Department of Energy (DOE) project started in 2004 and concluded in late...

  • Review
  • Open Access
65 Citations
15,948 Views
14 Pages

10 January 2019

In patients with chronic obstructive pulmonary disease (COPD), cardiovascular comorbidities are highly prevalent and associated with considerable morbidity and mortality. This coincidence is increasingly seen in context of a “cardiopulmonary co...

  • Article
  • Open Access
6 Citations
3,845 Views
15 Pages

Metabolic Response of Pancreatic Carcinoma Cells under Treatment with Dichloroacetate

  • Benedikt Feuerecker,
  • Philipp Biechl,
  • Christian Veltkamp,
  • Dieter Saur and
  • Wolfgang Eisenreich

In modern oncology, the analysis and evaluation of treatment response are still challenging. Hence, we used a 13C-guided approach to study the impacts of the small molecule dichloroacetate (DCA) upon the metabolic response of pancreatic cancer cells....

  • Article
  • Open Access
2 Citations
2,190 Views
17 Pages

Reduced Sodium Portions Favor Osteogenic Properties and Cytocompatibility of 45S5-Based Bioactive Glass Particles

  • Stefanos Tsitlakidis,
  • Frederike Hohenbild,
  • Merve Saur,
  • Arash Moghaddam,
  • Elke Kunisch,
  • Tobias Renkawitz,
  • Isabel Gonzalo de Juan and
  • Fabian Westhauser

Besides its favorable biological properties, the release of sodium (Na) from the well-known 45S5-bioactive glass (BG) composition (in mol%: 46.1, SiO2, 24.5 CaO, 24.5 Na2O, 6.0 P2O5) can hamper its cytocompatibility. In this study, particles of Na-re...

  • Article
  • Open Access
7 Citations
2,369 Views
14 Pages

The Addition of Zinc to the ICIE16-Bioactive Glass Composition Enhances Osteogenic Differentiation and Matrix Formation of Human Bone Marrow-Derived Mesenchymal Stromal Cells

  • Felix Rehder,
  • Marcela Arango-Ospina,
  • Simon Decker,
  • Merve Saur,
  • Elke Kunisch,
  • Arash Moghaddam,
  • Tobias Renkawitz,
  • Aldo R. Boccaccini and
  • Fabian Westhauser

An ICIE16-bioactive glass (BG) composition (in mol%: 49.5 SiO2, 6.6 Na2O, 36.3 CaO, 1.1 P2O5, and 6.6 K2O) has demonstrated excellent in vitro cytocompatibility when cultured with human bone marrow-derived mesenchymal stromal cells (BMSCs). However,...

  • Article
  • Open Access
9 Citations
4,455 Views
12 Pages

Small Airway Disease in Pulmonary Hypertension—Additional Diagnostic Value of Multiple Breath Washout and Impulse Oscillometry

  • Frederik Trinkmann,
  • Joshua Gawlitza,
  • Monique Künstler,
  • Julia Schäfer,
  • Michele Schroeter,
  • Julia D. Michels,
  • Ksenija Stach,
  • Christina Dösch,
  • Joachim Saur and
  • Ibrahim Akin
  • + 1 author

9 December 2018

Airways obstruction is frequent in patients with pulmonary hypertension (PH). Small airway disease (SAD) was identified as a major contributor to resistance and symptoms. However, it is easily missed using current diagnostic approaches. We aimed to e...

  • Article
  • Open Access
6 Citations
2,954 Views
12 Pages

Vacuum Arc Plasma Coating for Polymer Surface Protection— A Plasma Enhanced In-Orbit Additive Manufacturing Concept

  • Marina Kühn-Kauffeldt,
  • Marvin Kühn,
  • Michael Mallon,
  • Wolfgang Saur and
  • Fabian Fuchs

9 November 2022

In-orbit additive manufacturing (AM) is a promising approach for fabrication of large structures. It allows to expand and accelerate human space exploration possibilities. Extrusion-based AM was demonstrated in zero gravity, while the realization of...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,945 Views
16 Pages

CP Violation in Baryon Decays at LHCb

  • Xinchen Dai,
  • Miroslav Saur,
  • Yiduo Shang,
  • Xueting Yang and
  • Yanxi Zhang

15 February 2023

Observations in astronomy suggest that our Universe contains an abundance of matter over antimatter, which can only be explained if the combined CP symmetry is violated. Studies of CP violation have driven the flavor physics with the aim of testing t...

  • Article
  • Open Access
1,543 Views
15 Pages

30 September 2025

Small and medium-sized enterprises face significant challenges in effectively implementing design thinking due to limited resources, leadership skepticism, and a paucity of suitable frameworks. This study addresses these challenges by developing and...

  • Article
  • Open Access
722 Views
17 Pages

1 October 2025

Modern custom machine construction and automation projects face pressure to shorten innovation cycles, reduce durations, and manage growing system complexity. Traditional methods like Waterfall and V-Model have limits where end-to-end data traceabili...

  • Article
  • Open Access
6 Citations
10,934 Views
29 Pages

30 October 2015

This paper presents the results of the project IMPERA (Integrated Mission Planning for Distributed Robot Systems). The goal of IMPERA was to realize an extraterrestrial exploration scenario using a heterogeneous multi-robot system. The main challenge...

  • Article
  • Open Access
188 Views
15 Pages

Informing Intervention: An Exploration of Behavioral and Social–Emotional IEP Goals for Students with ASD

  • Sarah K. Cox,
  • Courtenay A. Barrett,
  • Goretty Chavez,
  • Rebecca Saur,
  • Megan Feury,
  • Grace Huber,
  • Brianna Booms and
  • Gabrielle Snyder

12 March 2026

Students with autism spectrum disorder (ASD) experience impairments in reciprocal social interactions, communication, and a restricted range of interests or repetitive behaviors that impact the development of their behavioral and/or social–emot...

  • Article
  • Open Access
24 Citations
6,095 Views
10 Pages

Multicenter 18F-PI-2620 PET for In Vivo Braak Staging of Tau Pathology in Alzheimer’s Disease

  • Michael Rullmann,
  • Matthias Brendel,
  • Matthias L. Schroeter,
  • Dorothee Saur,
  • Johannes Levin,
  • Robert G. Perneczky,
  • Solveig Tiepolt,
  • Marianne Patt,
  • Andre Mueller and
  • on behalf of the German Imaging Initiative for Tauopathies (GII4T)
  • + 5 authors

16 March 2022

Tau aggregates accumulate in the Alzheimer’s disease (AD) brain according to the established Braak staging scheme and spread from transentorhinal over limbic regions to the neocortex. To impact the management of AD patients, an in vivo tool for...

  • Article
  • Open Access
5 Citations
3,987 Views
23 Pages

Comparative Study of the Role of Interepithelial Mucosal Mast Cells in the Context of Intestinal Adenoma-Carcinoma Progression

  • Tanja Groll,
  • Miguel Silva,
  • Rim Sabrina Jahan Sarker,
  • Markus Tschurtschenthaler,
  • Theresa Schnalzger,
  • Carolin Mogler,
  • Daniela Denk,
  • Sebastian Schölch,
  • Barbara U. Schraml and
  • Katja Steiger
  • + 6 authors

30 April 2022

Mast cells (MCs) are crucial players in the relationship between the tumor microenvironment (TME) and cancer cells and have been shown to influence angiogenesis and progression of human colorectal cancer (CRC). However, the role of MCs in the TME is...

  • Article
  • Open Access
1 Citations
2,429 Views
23 Pages

31 January 2025

The development of personalized drugs introduces new uncertainties and risks in production machinery design, which can be mitigated through structured workflows. As the commonly used V-Model approach has limitations in dealing with complex multi-doma...

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