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7,663 Results Found

  • Article
  • Open Access
20 Citations
4,716 Views
15 Pages

15 July 2022

In recent years, open innovation and intellectual property rights have become critical factors to gain superior sustainable innovation performance. However, existing literature pays little attention to different open innovation strategies and their i...

  • Review
  • Open Access
17 Citations
6,212 Views
20 Pages

The Key Role of IP6K: A Novel Target for Anticancer Treatments?

  • Mirko Minini,
  • Alice Senni,
  • Vittorio Unfer and
  • Mariano Bizzarri

25 September 2020

Inositol and its phosphate metabolites play a pivotal role in several biochemical pathways and gene expression regulation: inositol pyrophosphates (PP-IPs) have been increasingly appreciated as key signaling modulators. Fluctuations in their intracel...

(This article belongs to the Special Issue Bioactivity of Inositol Phosphates)
  • Article
  • Open Access
7 Citations
3,640 Views
18 Pages

Modulation of KV4.3-KChIP2 Channels by IQM-266: Role of DPP6 and KCNE2

  • Angela de Benito-Bueno,
  • Paula G. Socuellamos,
  • Yaiza G. Merinero,
  • Pilar Cercos and ,
  • Carolina Izquierdo,
  • Miguel Daniel-Mozo,
  • Irene Marín-Olivero,
  • Angel Perez-Lara,
  • Juan A. Gonzalez-Vera and
  • Carmen Valenzuela
  • + 9 authors+ 4 authors

15 August 2022

The transient outward potassium current (Itof) is generated by the activation of KV4 channels assembled with KChIP2 and other accessory subunits (DPP6 and KCNE2). To test the hypothesis that these subunits modify the channel pharmacology, we analyzed...

(This article belongs to the Special Issue Membrane Channels in Physiology and Pathology)
  • Article
  • Open Access
3,000 Views
9 Pages

7 March 2022

Accumulating evidence suggests that the physical interactions between genomic regions play critical roles in the regulation of genome functions, such as transcription and epigenetic regulation. Various methods to detect the physical interactions betw...

(This article belongs to the Section Bioinformatics)
  • Feature Paper
  • Article
  • Open Access
2,136 Views
43 Pages

12 December 2025

In this work, a hypothesis is studied as to whether different DoS attacks affect the parameters of voice and video streams, as well as performance, on three different VoIP platforms. This research is a continuation of a previous work, which studied t...

  • Article
  • Open Access
33 Citations
23,624 Views
30 Pages

Integrating Intellectual Property and Sustainable Business Models: The SBM-IP Canvas

  • Roberto Hernández-Chea,
  • Pratheeba Vimalnath,
  • Nancy Bocken,
  • Frank Tietze and
  • Elisabeth Eppinger

26 October 2020

Companies attempt to address global sustainability challenges through innovating products, services, and business models. This paper focuses on sustainable business model (SBM) innovations as a way to systemically transform businesses towards sustain...

  • Review
  • Open Access
23 Citations
6,823 Views
13 Pages

IP3R Channels in Male Reproduction

  • Xiaoning Zhang,
  • Rongzu Huang,
  • Yang Zhou,
  • Wenwen Zhou and
  • Xuhui Zeng

2 December 2020

As a second messenger in cellular signal transduction, calcium signaling extensively participates in various physiological activities, including spermatogenesis and the regulation of sperm function. Abnormal calcium signaling is highly correlated wit...

(This article belongs to the Special Issue Trace Elements and Male Fertility)
  • Proceeding Paper
  • Open Access
10 Citations
4,638 Views
6 Pages

Voice over Internet Protocol (VoIP) is a recent technology used to transfer video and voice over the Internet Protocol (IP). Session Initiation Protocol (SIP) is the most widely used protocol for signaling functions in VoIP networks. However, the VoI...

(This article belongs to the Proceedings of The 1st International Conference on Computational Engineering and Intelligent Systems)
  • Article
  • Open Access
19 Citations
9,169 Views
26 Pages

29 August 2011

IP based Wireless Sensor Networks (IP-WSNs) are being used in healthcare, home automation, industrial control and agricultural monitoring. In most of these applications global addressing of individual IP-WSN nodes and layer-three routing for mobility...

(This article belongs to the Special Issue Selected Papers from FGIT 2010)
  • Article
  • Open Access
1 Citations
3,654 Views
18 Pages

Evaluating the Influence of ipRGCs on Color Discrimination

  • Masaya Ohtsu,
  • Akihiro Kurata,
  • Keita Hirai,
  • Midori Tanaka and
  • Takahiko Horiuchi

To investigate the influence of intrinsically photosensitive retinal ganglion cells (ipRGCs) on color discrimination, it is necessary to create two metameric light stimuli (metameric ipRGC stimuli) with the same amount of cone and rod stimulation, bu...

(This article belongs to the Special Issue Advances in Color Imaging)
  • Article
  • Open Access
6 Citations
2,911 Views
32 Pages

8 July 2024

In today’s digital world, no one and nothing is safe from potential cyberattacks. There is also no 100% protection from such attacks. Therefore, it is advisable to carry out various studies related to the effects of the different cyberattacks o...

  • Article
  • Open Access
6 Citations
4,691 Views
14 Pages

Performance Analysis of Raspberry Pi 3 IP PBX Based on Asterisk

  • Bilal Muhammad Khan,
  • Muhammad Fahad,
  • Rabia Bilal and
  • Ali Hanzala Khan

14 October 2022

IP-PBX have grown considerably in the telecoms and IT industries in recent times due to their low cost, high customizability, open source and hardware-independent nature. Unlike traditional PBX systems that are TDM-based and require a separate wired...

(This article belongs to the Section Circuit and Signal Processing)
  • Article
  • Open Access
4 Citations
3,103 Views
28 Pages

24 March 2025

This work studies the hypothesis of whether the UDP DoS attack affects voice and video flows in a VoIP network. It is a continuation of a previous work that studied the same hypothesis, but the VoIP server was under different types of TCP DoS attacks...

(This article belongs to the Section Cybersecurity)
  • Article
  • Open Access
7 Citations
4,546 Views
19 Pages

Protecting SOME/IP Communication via Authentication Ticket

  • Seulhui Lee,
  • Wonsuk Choi and
  • Dong Hoon Lee

11 July 2023

Designed using vehicle requirements, Scalable service-Oriented MiddlewarE over IP (SOME/IP) has been adopted and used as one of the Ethernet communication standard protocols in the AUTomotive Open System Architecture (AUTOSAR). However, SOME/IP was d...

(This article belongs to the Topic Next Generation of Security and Privacy in IoT, Industry 4.0, 5G Systems and Beyond)
  • Review
  • Open Access
37 Citations
6,261 Views
30 Pages

Steganography and Steganalysis in Voice over IP: A Review

  • Zhijun Wu,
  • Junjun Guo,
  • Chenlei Zhang and
  • Changliang Li

3 February 2021

The rapid advance and popularization of VoIP (Voice over IP) has also brought security issues. VoIP-based secure voice communication has two sides: first, for legitimate users, the secret voice can be embedded in the carrier and transmitted safely in...

(This article belongs to the Section Communications)
  • Communication
  • Open Access
8 Citations
6,686 Views
8 Pages

22 April 2021

Phoretic mites use bark beetles for transportation to new, suitable habitats. Some phoretic mites act as predators and parasitoids of the bark beetles’ immature stages, especially egg and early larval stages, and are potential agents for the biologic...

(This article belongs to the Section Forest Health)
  • Article
  • Open Access
806 Views
41 Pages

9 August 2026

Evaluating whether an intellectual property (IP) prototype faithfully preserves the visual identity and semantic intent of its original concept design is an important yet challenging task in product design and creative prototyping. Existing evaluatio...

(This article belongs to the Section Optical Sensors)
  • Technical Note
  • Open Access
4 Citations
16,640 Views
12 Pages

On the Cryptographic Features of a VoIP Service

  • Dimitrios Alvanos,
  • Konstantinos Limniotis and
  • Stavros Stavrou

Security issues of typical Voice over Internet Protocol (VoIP) applications are studied in this paper; in particular, the open source Linphone application is being used as a case study. An experimental analysis indicates that protecting signalling da...

  • Article
  • Open Access
78 Citations
16,371 Views
23 Pages

1 February 2011

IP based Wireless Sensor Networks (IP-WSNs) are gaining importance for their broad range of applications in health-care, home automation, environmental monitoring, industrial control, vehicle telematics and agricultural monitoring. In all these appli...

(This article belongs to the Section Physical Sensors)
  • Article
  • Open Access
9 Citations
26,504 Views
17 Pages

IP Spoofing In and Out of the Public Cloud: From Policy to Practice

  • Natalija Vlajic,
  • Mashruf Chowdhury and
  • Marin Litoiu

9 November 2019

In recent years, a trend that has been gaining particular popularity among cybercriminals is the use of public Cloud to orchestrate and launch distributed denial of service (DDoS) attacks. One of the suspected catalysts for this trend appears to be t...

  • Article
  • Open Access
5 Citations
3,739 Views
23 Pages

18 October 2022

Voice over IP is quickly becoming the industry standard voice communication service. While using an IP-based method of communication has many advantages, it also comes with a new set of challenges; voice networks are now accessible to a multitude of...

  • Proceeding Paper
  • Open Access
1,842 Views
5 Pages

Methodology for Rapid Security Testing of IP Cameras

  • Lidia Prudente-Tixteco,
  • Gabriel Sanchez-Perez,
  • Jesus Olivares-Mercado and
  • Aldo Hernandez-Suarez

11 February 2026

There are many types of IP surveillance cameras that connect to organizational or home data networks. However, these devices have vulnerabilities from their technological nature, and people often ignore procedures to protect their networks and device...

(This article belongs to the Proceedings of First Summer School on Artificial Intelligence in Cybersecurity)
  • Review
  • Open Access
18 Citations
6,218 Views
21 Pages

Pharmacological Approaches for the Modulation of the Potassium Channel KV4.x and KChIPs

  • Pilar Cercós,
  • Diego A. Peraza,
  • Angela de Benito-Bueno,
  • Paula G. Socuéllamos and ,
  • Abdoul Aziz-Nignan,
  • Dariel Arrechaga-Estévez,
  • Escarle Beato,
  • Emilio Peña-Acevedo,
  • Armando Albert and
  • Marta Gutiérrez-Rodríguez
  • + 9 authors+ 4 authors

31 January 2021

Ion channels are macromolecular complexes present in the plasma membrane and intracellular organelles of cells. Dysfunction of ion channels results in a group of disorders named channelopathies, which represent an extraordinary challenge for study an...

(This article belongs to the Special Issue Membrane Channels in Health and Diseases)
  • Article
  • Open Access
5 Citations
4,172 Views
14 Pages

A Clustering Approach for Motif Discovery in ChIP-Seq Dataset

  • Chun-xiao Sun,
  • Yu Yang,
  • Hua Wang and
  • Wen-hu Wang

16 August 2019

Chromatin immunoprecipitation combined with next-generation sequencing (ChIP-Seq) technology has enabled the identification of transcription factor binding sites (TFBSs) on a genome-wide scale. To effectively and efficiently discover TFBSs in the tho...

(This article belongs to the Section Entropy and Biology)
  • Article
  • Open Access
11 Citations
3,946 Views
19 Pages

Cellular and Subcellular Localisation of Kv4-Associated KChIP Proteins in the Rat Cerebellum

  • Rocío Alfaro-Ruíz,
  • Carolina Aguado,
  • Alejandro Martín-Belmonte,
  • Ana Esther Moreno-Martínez and
  • Rafael Luján

3 September 2020

The K+ channel interacting proteins (KChIPs) are a family of cytosolic proteins that interact with Kv4 channels, leading to higher current density, modulation of channel inactivation and faster recovery from inactivation. Using immunohistochemical te...

(This article belongs to the Special Issue Membrane Channels in Health and Diseases)
  • Article
  • Open Access
3 Citations
2,732 Views
37 Pages

16 February 2023

This article addresses the benefits of using IP network modeling platforms to study IP networks. For the purposes of this study, several models of IP networks were created, through which various hypotheses were studied. Additionally, different operat...

  • Article
  • Open Access
4 Citations
2,300 Views
24 Pages

29 September 2025

The rise of digital content has made the need for reliable and practical intellectual property (IP) management systems more critical than ever. Most traditional IP systems are prone to issues such as delays, inefficiency, and data security breaches....

(This article belongs to the Special Issue Blockchain and Web3: Applications, Challenges and Future Trends—2nd Edition)
  • Article
  • Open Access
1 Citations
3,785 Views
19 Pages

20 August 2021

IP fragmentation is still prevalent on the Internet. Defragmented traffic is a prerequisite for many network processing algorithms. This work focuses on the size and organization of a flow table, which is an essential ingredient of the hardware IP de...

(This article belongs to the Section Computer Science & Engineering)
  • Review
  • Open Access
8 Citations
5,203 Views
12 Pages

Current Application of iPS Cells in the Dental Tissue Regeneration

  • Sayuri Hamano,
  • Risa Sugiura,
  • Daiki Yamashita,
  • Atsushi Tomokiyo and ,
  • Daigaku Hasegawa and
  • Hidefumi Maeda
  • + 1 author+ 0 author

16 December 2022

When teeth and periodontal tissues are severely damaged by severe caries, trauma, and periodontal disease, such cases may be subject to tooth extraction. As tooth loss leads to the deterioration of quality of life, the development of regenerative med...

(This article belongs to the Special Issue Cell Biology in Dentistry)
  • Study Protocol
  • Open Access
3 Citations
1,680 Views
13 Pages

26 September 2023

Background: Preventable medical errors caused by ineffective teamwork are substantial contributors in the majority of patient harm events. Nonetheless, the interprofessional education (IPE) research to date has not reported on within-group interactio...

(This article belongs to the Special Issue Advances in Technology-Enhanced Teaching and Learning)
  • Feature Paper
  • Article
  • Open Access
3 Citations
1,707 Views
39 Pages

11 February 2026

This paper presents a methodology for studying the level of network security of VoIP platforms. The methodology is designed for VoIP platforms where the voice and video traffic passes through and are processed by the VoIP server itself, rather than b...

  • Article
  • Open Access
2 Citations
6,033 Views
14 Pages

This paper argues that Peter Drahos undertakes a partial Foucauldian genealogy by emancipating intellectual property (IP) from proprietarianism. He demonstrates the dominance of proprietarianism in IP by drawing sample practices from trademark, copyr...

(This article belongs to the Special Issue Beyond Foucault: Excursions in Political Genealogy)
  • Article
  • Open Access
5 Citations
10,740 Views
24 Pages

Evaluation Method of IP Geolocation Database Based on City Delay Characteristics

  • Yuancheng Xie,
  • Zhaoxin Zhang,
  • Yang Liu,
  • Enhao Chen and
  • Ning Li

Despite the widespread use of IP geolocation databases, a robust and precise method for evaluating their accuracy remains elusive. This study presents a novel algorithm designed to assess the reliability of IP geolocation databases, leveraging the co...

(This article belongs to the Special Issue Advances in Data Science: Methods, Systems, and Applications)
  • Article
  • Open Access
10 Citations
4,467 Views
21 Pages

29 December 2020

Inositol trisphosphate receptor (IP3R) mediated Ca+2 signaling is essential in determining the cell fate by regulating numerous cellular processes, including cell division and cell death. Despite extensive studies about the characterization of IP3R i...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Article
  • Open Access
9 Citations
11,053 Views
20 Pages

27 August 2015

Unlike CCTV, security video surveillance devices, which we have generally known about, IP cameras which are connected to a network either with or without wire, provide monitoring services through a built-in web-server. Due to the fact that IP cameras...

(This article belongs to the Special Issue Applied Cryptography and Security Concerns based on Symmetry for the Future Cyber World)
  • Article
  • Open Access
8 Citations
4,712 Views
21 Pages

Agonist-Induced Ca2+ Signaling in HEK-293-Derived Cells Expressing a Single IP3 Receptor Isoform

  • Ekaterina N. Kochkina,
  • Elizaveta E. Kopylova,
  • Olga A. Rogachevskaja,
  • Nina P. Kovalenko and ,
  • Natalia V. Kabanova,
  • Polina D. Kotova,
  • Marina F. Bystrova and
  • Stanislav S. Kolesnikov
  • + 3 authors+ 0 author

22 March 2024

In mammals, three genes encode IP3 receptors (IP3Rs), which are involved in agonist-induced Ca2+ signaling in cells of apparently all types. Using the CRISPR/Cas9 approach for disruption of two out of three IP3R genes in HEK-293 cells, we generated t...

(This article belongs to the Special Issue Advances in Dissecting Calcium Signaling Pathways in Health and Diseases)
  • Review
  • Open Access
20 Citations
7,322 Views
19 Pages

Potential Roles of IP3 Receptors and Calcium in Programmed Cell Death and Implications in Cardiovascular Diseases

  • Chanon Piamsiri,
  • Nadezhda Fefelova,
  • Sri Harika Pamarthi,
  • Judith K. Gwathmey and ,
  • Siriporn C. Chattipakorn,
  • Nipon Chattipakorn and
  • Lai-Hua Xie
  • + 2 authors+ 0 author

20 October 2024

Inositol 1,4,5-trisphosphate receptors (IP3Rs) play a crucial role in maintaining intracellular/cytosolic calcium ion (Ca2+i) homeostasis. The release of Ca2+ from IP3Rs serves as a second messenger and a modulatory factor influencing various intrace...

(This article belongs to the Section Cellular Biochemistry)
  • Review
  • Open Access
31 Citations
16,564 Views
23 Pages

Cellular and Molecular Activities of IP6 in Disease Prevention and Therapy

  • Lowell Dilworth,
  • Dewayne Stennett and
  • Felix Omoruyi

10 June 2023

IP6 (phytic acid) is a naturally occurring compound in plant seeds and grains. It is a poly-phosphorylated inositol derivative that has been shown to exhibit many biological activities that accrue benefits in health and diseases (cancer, diabetes, re...

(This article belongs to the Section Molecular Medicine)
  • Article
  • Open Access
8 Citations
4,042 Views
18 Pages

Atf7ip Inhibits Osteoblast Differentiation via Negative Regulation of the Sp7 Transcription Factor

  • Guoqin Hu,
  • Xian Shi,
  • Xiuxia Qu,
  • Chunqing Han and ,
  • Anran Hu,
  • Zhongtang Jia,
  • Jiatao Yang,
  • Huanliang Liu and
  • Yu Wu
  • + 4 authors+ 0 author

21 February 2023

Epigenetic modifications are critical for cell differentiation and growth. As a regulator of H3K9 methylation, Setdb1 is implicated in osteoblast proliferation and differentiation. The activity and nucleus localization of Setdb1 are regulated by its...

(This article belongs to the Special Issue Bone Development and Regeneration 3.0)
  • Article
  • Open Access
39 Citations
15,255 Views
22 Pages

RIDES: Robust Intrusion Detection System for IP-Based Ubiquitous Sensor Networks

  • Syed Obaid Amin,
  • Muhammad Shoaib Siddiqui,
  • Choong Seon Hong and
  • Sungwon Lee

11 May 2009

TheIP-based Ubiquitous Sensor Network (IP-USN) is an effort to build the “Internet of things”. By utilizing IP for low power networks, we can benefit from existing well established tools and technologies of IP networks. Along with many other unresolv...

(This article belongs to the Special Issue Wireless Sensor Technologies and Applications)
  • Article
  • Open Access
17 Citations
7,266 Views
13 Pages

Effects of Antidepressants on IP-10 Production in LPS-Activated THP-1 Human Monocytes

  • Jui-Hsiu Tsai,
  • Chang-Hung Kuo,
  • Pinchen Yang,
  • Kuang-Hung Cheng and ,
  • Peng-Wei Wang,
  • Cheng-Chung Chen and
  • Chih-Hsing Hung
  • + 2 authors+ 0 author

28 July 2014

Major depressive disorder and cardiovascular disease are common serious illnesses worldwide. Selective serotonin reuptake inhibitors and norepinephrine-dopamine reuptake inhibitors may reduce the mortality of cardiovascular disease patients with como...

(This article belongs to the Section Biochemistry)
  • Article
  • Open Access
2 Citations
3,547 Views
14 Pages

CtIP Regulates Mitotic Spindle Assembly by Modulating the TPX2-Aurora A Signaling Axis

  • Wonkyung Oh,
  • Ting Ting Wu,
  • Seo-Yeon Jeong,
  • Ho Jin You and
  • Jung-Hee Lee

8 September 2022

CtBP-interacting protein (CtIP) plays a critical role in controlling the homologous recombination-mediated DNA double-stranded break (DSB) repair pathway through DNA end resection, and recent studies suggest that it also plays a role in mitosis. Howe...

  • Review
  • Open Access
13 Citations
7,131 Views
18 Pages

20 January 2022

Cancer cells accumulate epigenomic aberrations that contribute to cancer initiation and progression by altering both the genomic stability and the expression of genes. The awareness of such alterations could improve our understanding of cancer dynami...

(This article belongs to the Special Issue Epigenetic Mechanisms and Human Pathology 2.0)
  • Article
  • Open Access
3 Citations
3,589 Views
11 Pages

26 September 2021

5G technology is spreading extremely quickly. Many services, including Voice Over Internet Protocol (VoIP), have utilized the features of 5G technology to improve their performance. VoIP service is gradually ruling the telecommunication sector due to...

  • Article
  • Open Access
178 Views
25 Pages

IOb-SoC-Linux: An Open-Source, Linux-Capable RISC-V SoC Template for IP Core Development

  • Artur Nóbrega,
  • João Barreiros Rodrigues,
  • Jaime Aguiar,
  • Jiao Li and
  • José T. de Sousa

27 October 2026

IOb-SoC-Linux is an open-source framework for configuring and generating Linux-capable System-on-Chip (SoC) designs targeting RISC-V processors. Built on the Py2HWSW hardware/software co-design framework, it provides a specialized SoC template that c...

(This article belongs to the Special Issue Innovations in Digital and Analog Electronic Systems for Next-Generation Devices: 2nd Edition)
  • Review
  • Open Access
64 Citations
10,152 Views
11 Pages

IP6 Regulation of HIV Capsid Assembly, Stability, and Uncoating

  • Robert A. Dick,
  • Donna L. Mallery,
  • Volker M. Vogt and
  • Leo C. James

15 November 2018

The mechanisms that drive formation of the HIV capsid, first as an immature particle and then as a mature protein shell, remain incompletely understood. Recent discoveries of positively-charged rings in the immature and mature protein hexamer subunit...

(This article belongs to the Special Issue Breakthroughs in Viral Replication)
  • Article
  • Open Access
3 Citations
2,754 Views
17 Pages

IP Spoofing Detection Using Deep Learning

  • İsmet Kaan Çekiş,
  • Buğra Ayrancı,
  • Fezayim Numan Salman and
  • İlker Özçelik

29 August 2025

IP spoofing is a critical component in many cyberattacks, enabling attackers to evade detection and conceal their identities. This study rigorously compares eight deep learning models—LSTM, GRU, CNN, MLP, DNN, RNN, ResNet1D, and xLSTM—for...

(This article belongs to the Section Computing and Artificial Intelligence)
  • Article
  • Open Access
4 Citations
7,748 Views
26 Pages

Evaluation of VoIP QoS Performance in Wireless Mesh Networks

  • Mohammad Tariq Meeran,
  • Paul Annus,
  • Muhammad Mahtab Alam and
  • Yannick Le Moullec

The main focus of this research article is the evaluation of selected voice over Internet protocol (VoIP) solutions in wireless mesh network (WMN) scenarios. While WMNs have self-healing, self-forming, and dynamic topology features, they still pose c...

(This article belongs to the Section Information Applications)
  • Article
  • Open Access
1 Citations
1,876 Views
20 Pages

15 November 2023

With the rapid development of technologies like artificial intelligence, high-performance computing chips are playing an increasingly vital role. The inverse hyperbolic sine and inverse hyperbolic cosine functions are of utmost importance in fields s...

(This article belongs to the Section Circuit and Signal Processing)
  • Article
  • Open Access
4 Citations
4,809 Views
20 Pages

RNAi Screening Uncovers a Synthetic Sick Interaction between CtIP and the BARD1 Tumor Suppressor

  • Hella A. Bolck,
  • Sara Przetocka,
  • Roger Meier,
  • Christine von Aesch and ,
  • Christina Zurfluh,
  • Kay Hänggi,
  • Vincent Spegg,
  • Matthias Altmeyer,
  • Michael Stebler and
  • Antonio Porro
  • + 8 authors+ 3 authors

12 February 2022

Human CtIP is best known for its role in DNA end resection to initiate DNA double-strand break repair by homologous recombination. Recently, CtIP has also been shown to protect reversed replication forks from nucleolytic degradation upon DNA replicat...

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