61 Results Found

Approximately half of the cases of chronic kidney disease (CKD) in childhood are caused by congenital anomalies of the kidney and urinary tract (CAKUT). Specific genes were identified as having significant importance in regard to the underlying genet...

Congenital anomalies of the kidney and urinary tract (CAKUT) are the third most common congenital anomaly and a significant public health concern. It is the predominant cause of chronic renal disease in pediatric populations and the principal reason...

Previous studies have shown that microRNAs (miRNAs) are closely related to many viral infections. However, the molecular mechanism of how miRNAs regulate porcine epidemic diarrhea virus (PEDV) infection remains unclear. In this study, we first constr...

An ethylenediamine (EDA) gas sensor based on a composite of MoO3 nanoribbon and reduced graphene oxide (rGO) was fabricated in this work. MoO3 nanoribbon/rGO composites were synthesized using a hydrothermal process. The crystal structure, morphology,...

Computed tomography (CT) is a major source of low-dose ionizing radiation exposure in medical imaging. Risk assessment at this dose level is difficult and relies on the hypothetical linear no-threshold model. To address the response to such low doses...

Clock tree synthesis (CTS) is an important process in determining overall chip timing and power consumption. The CTS is also a time-consuming process for checking the clock tree. If the chip design and specification do not match, the CTS result will...

Mutations within the ectodysplasin A (EDA) gene have been associated with congenital hypotrichosis and anodontia (HAD/XHED) in humans, mice, dogs and cattle. We identified a three-generation family of Fleckvieh cattle with male calves exhibiting clin...

Wearable sensors are widely used to gather psychophysiological data in the laboratory and real-world applications. However, the accuracy of these devices should be carefully assessed. The study focused on testing the accuracy of the Empatica 4 (E4) w...

Cervical cancer is a major cause of cancer death in women worldwide. Targeting human papillomavirus (HPV) viral oncoproteins E6 and E7 is a new strategy for cervical cancer immunotherapy and has been associated with resolution of HPV-induced lesions....

Background and Aims: Pulmonary Hypertension (PH) represents an aetiologically and clinically heterogeneous disorder accompanied by a severely impaired prognosis. Key steps of PH pathogenesis are vascular and right ventricular myocardial remodelling e...

Exposure to natural and artificial light and environmental pollutants are the main factors that challenge skin homeostasis, promoting aging or even different forms of skin cancer through a variety of mechanisms that include accumulation of reactive o...

This paper presents the findings of a 6-week long, five-participant experiment in a controlled climate chamber. The experiment was designed to understand the effect of time on thermal behaviour, electrodermal activity (EDA) and the adaptive behavior...

This paper investigates the selection of the best suitable eco-friendly organic and in-organic refrigerants for heating, ventilation, and air conditioning (HVAC) and renewable energy devices. Inorganic and organic refrigerants are used to cool renewa...

Cybersickness poses a significant challenge to the widespread adoption of virtual reality (VR), as it impairs user experience and operational performance. This study proposes a physiological modeling approach to objectively assess cybersickness sever...

Molecularly imprinted polymers@ethylenediamine-modified carbon dots grafted on cotton fabrics (MIPs@EDA-CDs/CF) and smartphone-based fluorescence image analysis were proposed and used for the first time for the detection of 17 α-methyltestoster...

Background/Objectives: There are strict demands on body weight and shape in highly trained adolescent female athletes, and they are in the highest risk group for the development of eating disorders. This study aims to compare the behavioural eating p...

Surface modified reduced graphene oxide (rGO) aerogels were synthesized using the hydrothermal method. Ethylene diamine (EDA) and α-cyclodextrin (CD) were used to functionalize the surface of the graphene oxide layers. The oxygen reduction and...

Driver monitoring systems are increasingly relying on physiological signals to assess cognitive and emotional states for improved safety and user experience. Electrodermal activity (EDA) is a particularly informative biomarker of arousal but is conve...

Tooth agenesis (TA), the congenital absence of one or more teeth, is the most common manifestation of defective dental morphogenesis in humans. TA can occur as an isolated (non-syndromic) condition or as part of a broader syndromic presentation. In t...

Amorphous nano zero-valent iron (A-nZVI) was synthesized via liquid-phase reduction and ethylenediamine (EDA) modification to enhance trichloroethylene (TCE) dechlorination. A-nZVI showed a cauliflower-like morphology, where 20–50 nm primary pa...

Early wildfire smoke detection faces challenges such as limited datasets, small target sizes, and interference from smoke-like objects. To address these issues, we propose a novel approach leveraging Efficient Channel and Dilated Convolution Spatial...

Perception and expression of pain in cancer patients are influenced by distress levels, tumor type and progression, and the underlying pathophysiology of pain. Relying on traditional pain assessment tools can present limitations due to the highly sub...

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by periods of exacerbation and remission, making disease monitoring and management challenging. Endoscopy, the gold standard for assessing disease activity and severity, in...

Quantification of pain or discomfort induced by pressure is essential for understanding human responses to physical stimuli and improving user interfaces. Pain research has been conducted to investigate physiological signals associated with discomfor...

As we increasingly use advanced technology nodes to design integrated circuits (ICs), physical designers and electronic design automation (EDA) providers are facing multiple challenges, firstly, to honor all physical constraints coming with cutting-e...

Data from a moderate resolution imaging spectroradiometer instrument onboard the Terra satellite along with a radiative transfer model and a machine learning technique were integrated to predict direct solar irradiance on a horizontal surface over th...

This study aimed to develop a non-invasive blood glucose estimation method by integrating wearable multimodal signals, including photoplethysmography (PPG), electrodermal activity (EDA), and skin temperature (ST), with food log–derived nutritio...

Mental stress is known as a prime factor in road crashes. The devastation of these crashes often results in damage to humans, vehicles, and infrastructure. Likewise, persistent mental stress could lead to the development of mental, cardiovascular, an...

The cell non-targeted metabolomics technique was used to investigate the potential mechanism of Caly-cosin-7-O-β-d-glucoside (CAG) against cell oxygen–glucose deprivation/reperfusion (OGD/R). The OGD/R-injured HT22 cell model was construct...

Power optimization is a very important and challenging step in the physical design flow, and it is a critical success factor of an application-specific integrated circuit (ASIC) chip. Many techniques are used by the place and route (P&R) electron...

Inflammatory bowel disease (IBD), especially Crohn’s disease (CD), characterized by a chronic inflammatory process and progressive intestinal tissue damage, leads to the unrestrained proliferation of mesenchymal cells and the development of bow...

In this study, a semi-empirical model that was originally developed for stem volume estimation is used for aboveground biomass (AGB) estimation of a spruce dominated alpine forest. The reference AGB of the available sample plots is calculated from fo...

Modelling events that change over time is one of the most difficult problems in data analysis. Forecasting of time-varying electric power values is also an important problem in data analysis. Regression methods, machine learning, and deep learning me...

Behavioral factors can affect the blood glucose (BG) levels in people with type 1 diabetes (T1D), therefore, their effects need to be incorporated in blood glucose management for these individuals. Accordingly, in this work, we study the effect of tw...

Two mixed peri-substituted phosphine-chlorostibines, Acenap(PiPr2)(SbPhCl) and Acenap(PiPr2)(SbCl2) (Acenap = acenaphthene-5,6-diyl) reacted cleanly with Grignard reagents or nBuLi to give the corresponding tertiary phosphine-stibines Acenap(PiPr2)(S...

The epidermal growth factor receptor (EGFR) plays a central role in the progression of many solid tumors. We used this validated target to analyze the de novo design of EGFR-binding peptides and their application for the delivery of complex payloads...

Technology mapping is an essential process in the Electronic Design Automation (EDA) flow which aims to find an optimal implementation of a logic network from a technology library. In application-specific integrated circuit (ASIC) designs, the non-li...

PM2.5 pollution is increasing, causing health problems. The objective of this study was to model the behavior of PM2.5AQI (air quality index) using machine learning (ML) predictive models of linear regression, lasso, ridge, and elastic net. A total o...

Stress is a physical, mental, or emotional response to a change and is a significant problem in modern society. In addition to questionnaires, levels of stress may be assessed by monitoring physiological signals, such as via photoplethysmogram (PPG),...

This study assessed the contributions of urban green spaces on mental health with joint consideration of people’s physiological and psychological responses. The psychological and physiological responses of participants aged between 22 and 28, who vis...

The successful completion of reinforced concrete (RC) building construction projects depends, in part, on selecting the appropriate formwork system (FWS) since it may significantly affect the project’s cost, time, and quality performance factor...

We report a broad theoretical study on [(PMe3)3MER]+ complexes, with M = Ni, Pd, Pt, E = C, Si, Ge, Sn, Pb, and R = ArMes, Tbb, (ArMes = 2,6-dimesitylphenyl; Tbb = C6H2-2,6-[CH(SiMe3)2]2-4-tBu). A few years ago, our group succeeded in obtaining heavi...

We report on a cohort of 204 children referred between January 2017 and January 2022 to the German Center for Ectodermal Dysplasias, Erlangen. The most frequent reasons for referral were tooth malformations and lack of multiple teeth leading to the s...

Background: As technology becomes more sophisticated, more accessible methods of interpretating Big Data become essential. We have continued to develop Complexity and Entropy in Physiological Signals (CEPS) as an open access MATLAB® GUI (graphica...

Animal models are invaluable in the research of the pathophysiology of interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic aseptic urinary bladder disease of unknown etiology that primarily affects women. Here, a mouse model of IC/BPS was...

Stress is a natural yet potentially harmful aspect of human life, necessitating effective management, particularly during overwhelming experiences. This paper presents a scoping review of personalized stress detection models using wearable technology...

The aim of this paper is to present the use of an innovative approach based on MCDM methods as the main component of a consumer Decision Support System (DSS) by recommending the most suitable products among a given set of alternatives. This system pr...

Centrifugal pumps are essential in various industries, where their operational stability and efficiency are crucial. This study aims to analyze the composition and variation characteristics of the hydraulic radial force on the impeller using a data-c...

Single nucleotide polymorphisms located in 5′ untranslated regions (5′UTRs) can regulate gene expression and have clinical impact. Recognition of functionally significant sequences within 5′UTRs is crucial in next-generation sequenc...

Early detection and prevention of stress is crucial because stress affects our vital signs like heart rate, blood pressure, skin temperature, respiratory rate, and heart rate variability. There are different ways to determine stress using different d...