118 Results Found

The cultivation of abalone, a species with high economic value, faces significant challenges due to its slow growth rate and sensitivity to environmental conditions, resulting in prolonged cultivation periods and increased mortality risks. To address...

We propose a Bayesian kernel machine regression (BKMR) framework for count outcomes with dynamic spatiotemporal dependence. The proposed model, termed Negative Binomial BKMR with spatiotemporal effects (NB-BKMR), integrates (i) a negative binomial li...

Large-scale population datasets are rarely generated via simple random sampling; instead, they reflect complex designs involving stratification, clustering, and unequal inclusion probabilities. While survey weights are provided to recover population-...

High blood pressure (BP) is a significant risk factor for heart and brain diseases. Previous studies have suggested that heavy metals including lead (Pb), mercury (Hg), and cadmium (Cd) contribute to hypertension. This study examined the combined eff...

Background/Objective: This study aimed to investigate the effect of exposure to per- and polyfluoroalkyl substances (PFAS), a class of organic compounds utilized in commercial and industrial applications, on allostatic load (AL), a measure of chronic...

This study aims to investigate the combined effects of per- and polyfluoroalkyl substances (PFAS) on allostatic load, an index of chronic stress that is linked to several chronic diseases, including cardiovascular disease and cancer. Using data from...

Considering the ever-growing demand for an efficient method of deductive mining and extrapolative analysis of large-scale dimensional datasets, it is very critical to explore advanced machine learning models and algorithms that can reliably meet the...

Human per- and polyfluoroalkyl substances (PFAS) and metal exposures occur as mixtures, but most studies evaluate them independently. Using data from adults in the 2017–2018 National Health and Nutrition Examination Survey (NHANES) with directl...

Chronic kidney disease (CKD) is a noteworthy global health issue affecting 10% of the world’s populace. It is increasingly linked to environmental exposures; however, the interplay of toxic metals, per- and polyfluoroalkyl substances (PFAS), an...

Growing evidence supports the associations of metal exposures with risk of type 2 diabetes (T2D), but the methodological limitations overlook the complexity of relationships within the metal mixtures. We identified and estimated the single and combin...

The causes of visual impairment are complex and may be influenced by exposure to environmental pollutants. Using data from the 2003–2004 National Health and Nutrition Examination Survey (NHANES), we examined the association between exposure to...

Perfluoroalkyl substances (PFASs) possess immunosuppressive properties. However, their association with rheumatoid arthritis (RA) risk remains inconclusive across epidemiological studies. This study integrates population-based and mechanistic evidenc...

The association between manganese (Mn) and metabolic syndrome (MetS) is unclear, and no prior study has studied this association longitudinally. The aim of this study was to assess longitudinal associations of Mn exposure with MetS and metabolic outc...

Bisphenols are endocrine disruptors that may be associated with altered fetal growth in humans, and they have similar biological functions to mimic hormones. In addition, aggregated chemicals showed an adverse effect although individual concentration...

Background: Heavy metals and per- and polyfluoroalkyl substances (PFAS) are widespread environmental pollutants that have been linked to worsening cognition, but how the two classes act together to shape cognitive function is still not well character...

Coking activities produce high concentrations of aromatic compounds (ACs) and related substances, which may have impacts on human health. However, the health effects of these substances on humans exposed to coking sites have not been fully elucidated...

Environmental exposures to heavy metals, polychlorinated biphenyls (PCBs), dioxins, and furans have been associated with adverse cardiovascular outcomes, yet their combined effects remain underexplored. This study examined the joint influence of thes...

Many studies suggest a significant association between individual essential trace elements (ETEs) and cognitive impairment in older adults, but evidence of the synchronized effect of multiple ETEs on cognitive function is lacking. We investigated the...

Background: Human exposure to environmental endocrine-disrupting chemicals (EDCs) rarely occurs in isolation, yet most epidemiological research has assessed chemicals individually. PFASs, toxic metals, phthalates, and VOCs are ubiquitous contaminants...

This study assessed the relationship between environmental chemical mixtures—including metals, per- and polyfluoroalkyl substances (PFAS), phthalates, and plasticizers—and key cardiovascular health markers using data from the 2013–2...

Streamflow forecasting is a vital task for hydrology and water resources engineering, and the different artificial intelligence (AI) approaches have been employed for this purposes until now. Additionally, the forecasting accuracy and uncertainty est...

Per- and polyfluoroalkyl substances (PFAS) are persistent contaminants with growing evidence of systemic health effects, but their potential influence on gastrointestinal function remains poorly understood. This study evaluated associations between s...

Environmental contaminants such as per- and polyfluoroalkyl substances (PFAS) and toxic metals have been implicated in biological aging, yet their combined effects remain poorly understood. This study evaluated the associations of PFAS, lead, and cad...

Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are widely used in consumer products. However, the role of PFAS in infertility is still poorly understood. A total of 788 women from the 2013–2016 nationally representative NHANES were inclu...

Background: Liver disease is a growing global health burden. While individual environmental exposures like heavy metals (lead, cadmium, mercury) and behavioral factors such as smoking and alcohol use are known risk factors, their combined impact...

The main objective of our study is to explore the associations between combined exposure to urinary heavy metals and high remnant cholesterol (HRC), a known cardiovascular risk factor. Utilizing data from the National Health and Nutrition Examination...

Liver diseases, including non-alcoholic fatty liver disease (NAFLD), are a growing global health issue. Environmental exposure to toxic metals can harm the liver, increasing the risk of NAFLD. Essential elements are vital for liver health, but imbala...

Per- and polyfluoroalkyl substances (PFASs) are ubiquitous environmental contaminants with potential endocrine-disrupting properties. This study examines the association between exposure to multiple PFASs and pan-cancers associated with sex hormones...

Background: While current epidemiological studies have documented associations between environmental metals and renal dysfunction, the majority have concentrated on plasma metal levels. The relationship between urinary metal exposure and chronic kidn...

People are exposed to mixtures of metals, per- and polyfluoroalkyl substances (PFAS), phthalates, and polycyclic aromatic hydrocarbons (PAH) rather than single chemicals, yet mixture inference is hampered by high dimensionality, correlation, missingn...

Background: Chronic stress, characterized by sustained activation of physiological stress response systems, is a key risk factor for numerous health conditions. Allostatic load (AL), a biomarker of cumulative physiological stress, offers a quantitati...

This study investigates the combined effects of environmental pollutants (lead, cadmium, total mercury) and behavioral factors (alcohol consumption, smoking) on depressive symptoms in women. Data from the National Health and Nutrition Examination Sur...

Background: Chronic stress, driven by the persistent activation of the body’s stress response system—including the sympathetic nervous system and hypothalamic–pituitary–adrenal (HPA) axis—has far-reaching effects on both...

Background: The global burden of chronic diseases has been increasing, with evidence suggesting that diet and exposure to environmental pollutants, such as per- and polyfluoroalkyl substances (PFAS) and heavy metals, may contribute to their developme...

Background: Exposure to environmental pollutants such as metals and Per- and Polyfluoroalkyl Substances (PFAS) has become common and increasingly associated with a decrease in the estimated Glomerular Filtration Rate (eGFR), which is a marker often u...

Background: Human lead exposure is a multi-pathway phenomenon that integrates internal biological burden with persistent residential environmental reservoirs. Although individual lead metrics have been linked to cardiometabolic dysfunction, current r...

Background. Human populations are exposed to complex chemical mixtures, making interaction detection a central challenge in environmental epidemiology. We benchmarked methods for prediction and recovery of interaction structure. Methods. Eight approa...

Endometrial cancer (EC) is a growing public health concern. This secondary data study of a case series leveraged existing samples and data to explore the potential link between exposure to heavy metals/essential elements and stage of EC. We analyzed...

The information about phytochemicals’ potential to prevent cancer is encouraging, including for glioma. However, most studies on phytochemicals and glioma mainly focused on preclinical studies. Their epidemiological studies were not sufficient,...

Olive flounder (Paralichthys olivaceus) is a key aquaculture species in South Korea, but its production has been challenged by rising mortality under environmental stress from key environmental factors such as water temperature, dissolved oxygen, and...

We propose a new fault diagnosis model for rolling bearings based on a hybrid kernel support vector machine (SVM) and Bayesian optimization (BO). The model uses discrete Fourier transform (DFT) to extract fifteen features from vibration signals in th...

We present Bayesian Binary Search (BBS), a novel framework that bridges statistical learning theory/probabilistic machine learning and binary search. BBS utilizes probabilistic methods to learn the underlying probability density of the search space....

Geophysical logging is an essential measurement tool in the oil/gas exploration and development field. In practice, predicting missing well logs is an effective way to reduce the exploration expenses. Because of the complexity and heterogeneity of th...

Background: Environmental exposures, such as per- and polyfluoroalkyl substances (PFAS), in conjunction with social and behavioral factors, can significantly impact liver health. This research investigates the combined effects of PFAS (perfluorooctan...

There is an argument that BPA substitutes may have the same or more deleterious health effects as BPA due to their structural similarity. This study explored the association between urinary BPA substitutes and precocious puberty among girls by includ...

Background: There is limited research on the associations between serum nutritional biomarkers and mortality risk in patients with metabolic syndrome (MetS). Existing studies merely investigated the single-biomarker effect. Thus, this study aimed to...

Depressive symptoms are common in older adults and may be influenced by environmental element exposure. This study evaluated associations of individual and mixed blood element concentrations with depressive symptoms in older adults. A total of 1302 c...

Predicting innovation outcomes at the firm level continues to be an important but challenging goal for researchers and practitioners alike. In this study, multiple machine learning models, encompassing both ensemble-based and single-model approaches,...

Cardiovascular diseases (CVDs) are the leading cause of mortality globally, accounting for approximately one-third of all deaths. Exposure to toxic metals poses significant risks to cardiovascular health, contributing to the development of CVDs. Esse...

Exposure to insecticides may result in various health problems. This study investigated the association between haematological parameters and exposure to a mixture of organophosphate (OP) and neonicotinoid (NEO) insecticides among male farmworkers in...