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100 Results Found

  • Article
  • Open Access
1 Citations
1,602 Views
16 Pages

A Weighted Bayesian Kernel Machine Regression Approach for Predicting the Growth of Indoor-Cultured Abalone

  • Seung-Won Seo,
  • Gyumin Choi,
  • Ho-Jin Jung,
  • Mi-Jin Choi,
  • Young-Dae Oh,
  • Hyun-Seok Jang,
  • Han-Kyu Lim and
  • Seongil Jo

13 January 2025

The cultivation of abalone, a species with high economic value, faces significant challenges due to its slow growth rate and sensitivity to environmental conditions, resulting in prolonged cultivation periods and increased mortality risks. To address...

  • Article
  • Open Access
1 Citations
1,547 Views
13 Pages

Sex-Specific Effects of Combined Heavy Metal Exposure on Blood Pressure: A Bayesian Kernel Machine Regression Analysis

  • In-Gwon Kim,
  • Seonmi Hong,
  • Sojeong Yim,
  • Jang-Hun Jeong,
  • Kyunghi Choi,
  • Ju-Hee Lee,
  • Young-Seoub Hong,
  • Sang-Yong Eom,
  • Heon Kim and
  • Yong-Dae Kim

27 September 2024

High blood pressure (BP) is a significant risk factor for heart and brain diseases. Previous studies have suggested that heavy metals including lead (Pb), mercury (Hg), and cadmium (Cd) contribute to hypertension. This study examined the combined eff...

  • Article
  • Open Access
4 Citations
3,765 Views
12 Pages

22 March 2023

Background/Objective: This study aimed to investigate the effect of exposure to per- and polyfluoroalkyl substances (PFAS), a class of organic compounds utilized in commercial and industrial applications, on allostatic load (AL), a measure of chronic...

  • Article
  • Open Access
7 Citations
4,097 Views
22 Pages

This study aims to investigate the combined effects of per- and polyfluoroalkyl substances (PFAS) on allostatic load, an index of chronic stress that is linked to several chronic diseases, including cardiovascular disease and cancer. Using data from...

  • Article
  • Open Access
5 Citations
3,222 Views
22 Pages

Machine Learning-Based GPR with LBFGS Kernel Parameters Selection for Optimal Throughput Mining in 5G Wireless Networks

  • Joseph Isabona,
  • Agbotiname Lucky Imoize,
  • Stephen Ojo,
  • Dinh-Thuan Do and
  • Cheng-Chi Lee

15 January 2023

Considering the ever-growing demand for an efficient method of deductive mining and extrapolative analysis of large-scale dimensional datasets, it is very critical to explore advanced machine learning models and algorithms that can reliably meet the...

  • Article
  • Open Access
1 Citations
2,360 Views
21 Pages

Chronic kidney disease (CKD) is a noteworthy global health issue affecting 10% of the world’s populace. It is increasingly linked to environmental exposures; however, the interplay of toxic metals, per- and polyfluoroalkyl substances (PFAS), an...

  • Article
  • Open Access
20 Citations
3,825 Views
13 Pages

8 April 2022

Growing evidence supports the associations of metal exposures with risk of type 2 diabetes (T2D), but the methodological limitations overlook the complexity of relationships within the metal mixtures. We identified and estimated the single and combin...

  • Article
  • Open Access
4 Citations
2,395 Views
16 Pages

29 October 2024

The causes of visual impairment are complex and may be influenced by exposure to environmental pollutants. Using data from the 2003–2004 National Health and Nutrition Examination Survey (NHANES), we examined the association between exposure to...

  • Article
  • Open Access
1,890 Views
14 Pages

Perfluoroalkyl substances (PFASs) possess immunosuppressive properties. However, their association with rheumatoid arthritis (RA) risk remains inconclusive across epidemiological studies. This study integrates population-based and mechanistic evidenc...

  • Article
  • Open Access
11 Citations
2,873 Views
14 Pages

A Longitudinal Study of Exposure to Manganese and Incidence of Metabolic Syndrome

  • Emily Riseberg,
  • Kenneth Chui,
  • Katherine A. James,
  • Rachel Melamed,
  • Tanya L. Alderete and
  • Laura Corlin

13 October 2022

The association between manganese (Mn) and metabolic syndrome (MetS) is unclear, and no prior study has studied this association longitudinally. The aim of this study was to assess longitudinal associations of Mn exposure with MetS and metabolic outc...

  • Article
  • Open Access
23 Citations
3,456 Views
13 Pages

Urinary Concentrations of Bisphenol Mixtures during Pregnancy and Birth Outcomes: The MAKE Study

  • Seyoung Kim,
  • Eunjung Park,
  • Eun-Kyo Park,
  • Seulbi Lee,
  • Jeoung-A Kwon,
  • Bo-Hye Shin,
  • Sora Kang,
  • Eun-Young Park and
  • Byungmi Kim

Bisphenols are endocrine disruptors that may be associated with altered fetal growth in humans, and they have similar biological functions to mimic hormones. In addition, aggregated chemicals showed an adverse effect although individual concentration...

  • Article
  • Open Access
1,962 Views
35 Pages

Environmental exposures to heavy metals, polychlorinated biphenyls (PCBs), dioxins, and furans have been associated with adverse cardiovascular outcomes, yet their combined effects remain underexplored. This study examined the joint influence of thes...

  • Article
  • Open Access
761 Views
18 Pages

11 April 2025

Coking activities produce high concentrations of aromatic compounds (ACs) and related substances, which may have impacts on human health. However, the health effects of these substances on humans exposed to coking sites have not been fully elucidated...

  • Article
  • Open Access
3 Citations
2,351 Views
12 Pages

Association between Multiple Trace Elements, Executive Function, and Cognitive Impairment with No Dementia in Older Adults

  • Seung-Woo Ryoo,
  • Baek-Yong Choi,
  • Seok-Yoon Son,
  • Kun-Hee Oh,
  • Jin-Young Min and
  • Kyoung-Bok Min

29 March 2024

Many studies suggest a significant association between individual essential trace elements (ETEs) and cognitive impairment in older adults, but evidence of the synchronized effect of multiple ETEs on cognitive function is lacking. We investigated the...

  • Article
  • Open Access
1 Citations
1,964 Views
18 Pages

5 June 2025

This study assessed the relationship between environmental chemical mixtures—including metals, per- and polyfluoroalkyl substances (PFAS), phthalates, and plasticizers—and key cardiovascular health markers using data from the 2013–2...

  • Article
  • Open Access
22 Citations
4,230 Views
22 Pages

21 November 2020

Streamflow forecasting is a vital task for hydrology and water resources engineering, and the different artificial intelligence (AI) approaches have been employed for this purposes until now. Additionally, the forecasting accuracy and uncertainty est...

  • Article
  • Open Access
1 Citations
1,118 Views
27 Pages

30 October 2025

Background: Liver disease is a growing global health burden. While individual environmental exposures like heavy metals (lead, cadmium, mercury) and behavioral factors such as smoking and alcohol use are known risk factors, their combined impact...

  • Article
  • Open Access
17 Citations
7,344 Views
15 Pages

Association between Perfluoroalkyl and Polyfluoroalkyl Substances and Women’s Infertility, NHANES 2013–2016

  • Yuxuan Tan,
  • Zurui Zeng,
  • Huanzhu Liang,
  • Xueqiong Weng,
  • Huojie Yao,
  • Yingyin Fu,
  • Yexin Li,
  • Jingmin Chen,
  • Xiangcai Wei and
  • Chunxia Jing

Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are widely used in consumer products. However, the role of PFAS in infertility is still poorly understood. A total of 788 women from the 2013–2016 nationally representative NHANES were inclu...

  • Article
  • Open Access
9 Citations
3,286 Views
14 Pages

13 June 2024

The main objective of our study is to explore the associations between combined exposure to urinary heavy metals and high remnant cholesterol (HRC), a known cardiovascular risk factor. Utilizing data from the National Health and Nutrition Examination...

  • Article
  • Open Access
7 Citations
4,608 Views
18 Pages

Liver diseases, including non-alcoholic fatty liver disease (NAFLD), are a growing global health issue. Environmental exposure to toxic metals can harm the liver, increasing the risk of NAFLD. Essential elements are vital for liver health, but imbala...

  • Article
  • Open Access
1 Citations
1,571 Views
21 Pages

14 June 2025

Per- and polyfluoroalkyl substances (PFASs) are ubiquitous environmental contaminants with potential endocrine-disrupting properties. This study examines the association between exposure to multiple PFASs and pan-cancers associated with sex hormones...

  • Article
  • Open Access
2 Citations
2,567 Views
20 Pages

Association Between Urinary Metal Levels and Chronic Kidney Dysfunction in Rural China: A Study on Sex-Specific Differences

  • Kaisheng Teng,
  • Qinyi Guan,
  • Qiumei Liu,
  • Xiaoting Mo,
  • Lei Luo,
  • Jiahui Rong,
  • Tiantian Zhang,
  • Wenjia Jin,
  • Linhai Zhao and
  • Jian Qin
  • + 2 authors

14 January 2025

Background: While current epidemiological studies have documented associations between environmental metals and renal dysfunction, the majority have concentrated on plasma metal levels. The relationship between urinary metal exposure and chronic kidn...

  • Article
  • Open Access
1 Citations
1,280 Views
27 Pages

1 November 2025

People are exposed to mixtures of metals, per- and polyfluoroalkyl substances (PFAS), phthalates, and polycyclic aromatic hydrocarbons (PAH) rather than single chemicals, yet mixture inference is hampered by high dimensionality, correlation, missingn...

  • Article
  • Open Access
2 Citations
2,652 Views
21 Pages

7 January 2025

Background: Chronic stress, characterized by sustained activation of physiological stress response systems, is a key risk factor for numerous health conditions. Allostatic load (AL), a biomarker of cumulative physiological stress, offers a quantitati...

  • Article
  • Open Access
4 Citations
3,170 Views
18 Pages

2 December 2024

This study investigates the combined effects of environmental pollutants (lead, cadmium, total mercury) and behavioral factors (alcohol consumption, smoking) on depressive symptoms in women. Data from the National Health and Nutrition Examination Sur...

  • Article
  • Open Access
1 Citations
3,543 Views
17 Pages

4 February 2025

Background: Chronic stress, driven by the persistent activation of the body’s stress response system—including the sympathetic nervous system and hypothalamic–pituitary–adrenal (HPA) axis—has far-reaching effects on both...

  • Article
  • Open Access
6 Citations
4,168 Views
17 Pages

Background: The global burden of chronic diseases has been increasing, with evidence suggesting that diet and exposure to environmental pollutants, such as per- and polyfluoroalkyl substances (PFAS) and heavy metals, may contribute to their developme...

  • Article
  • Open Access
16 Citations
4,633 Views
22 Pages

Background: Exposure to environmental pollutants such as metals and Per- and Polyfluoroalkyl Substances (PFAS) has become common and increasingly associated with a decrease in the estimated Glomerular Filtration Rate (eGFR), which is a marker often u...

  • Article
  • Open Access
7 Citations
2,971 Views
16 Pages

Phytochemicals and Glioma: Results from Dietary Mixed Exposure

  • Weichunbai Zhang,
  • Ce Wang,
  • Feng Chen,
  • Yongqi He,
  • Shuo Yin,
  • Yue Peng and
  • Wenbin Li

The information about phytochemicals’ potential to prevent cancer is encouraging, including for glioma. However, most studies on phytochemicals and glioma mainly focused on preclinical studies. Their epidemiological studies were not sufficient,...

  • Article
  • Open Access
1 Citations
1,867 Views
16 Pages

The Combined Effects of Urine Zinc, Cadmium, Mercury, Lead, and Copper on Endometrial Cancer Staging

  • Issah Haruna,
  • Russell R. Broaddus,
  • Andrew B. Gladden,
  • Kiran Subedi and
  • Emmanuel Obeng-Gyasi

Endometrial cancer (EC) is a growing public health concern. This secondary data study of a case series leveraged existing samples and data to explore the potential link between exposure to heavy metals/essential elements and stage of EC. We analyzed...

  • Article
  • Open Access
837 Views
16 Pages

Predicting Flatfish Growth in Aquaculture Using Bayesian Deep Kernel Machines

  • Junhee Kim,
  • Seung-Won Seo,
  • Ho-Jin Jung,
  • Hyun-Seok Jang,
  • Han-Kyu Lim and
  • Seongil Jo

29 August 2025

Olive flounder (Paralichthys olivaceus) is a key aquaculture species in South Korea, but its production has been challenged by rising mortality under environmental stress from key environmental factors such as water temperature, dissolved oxygen, and...

  • Article
  • Open Access
40 Citations
4,746 Views
26 Pages

Bayesian-Optimized Hybrid Kernel SVM for Rolling Bearing Fault Diagnosis

  • Xinmin Song,
  • Weihua Wei,
  • Junbo Zhou,
  • Guojun Ji,
  • Ghulam Hussain,
  • Maohua Xiao and
  • Guosheng Geng

28 May 2023

We propose a new fault diagnosis model for rolling bearings based on a hybrid kernel support vector machine (SVM) and Bayesian optimization (BO). The model uses discrete Fourier transform (DFT) to extract fifteen features from vibration signals in th...

  • Article
  • Open Access
3 Citations
2,465 Views
27 Pages

Bayesian Binary Search

  • Vikash Singh,
  • Matthew Khanzadeh,
  • Vincent Davis,
  • Harrison Rush,
  • Emanuele Rossi,
  • Jesse Shrader and
  • Pietro Lio’

22 July 2025

We present Bayesian Binary Search (BBS), a novel framework that bridges statistical learning theory/probabilistic machine learning and binary search. BBS utilizes probabilistic methods to learn the underlying probability density of the search space....

  • Article
  • Open Access
13 Citations
2,442 Views
14 Pages

4 August 2022

Geophysical logging is an essential measurement tool in the oil/gas exploration and development field. In practice, predicting missing well logs is an effective way to reduce the exploration expenses. Because of the complexity and heterogeneity of th...

  • Article
  • Open Access
2 Citations
2,041 Views
25 Pages

Background: Environmental exposures, such as per- and polyfluoroalkyl substances (PFAS), in conjunction with social and behavioral factors, can significantly impact liver health. This research investigates the combined effects of PFAS (perfluorooctan...

  • Article
  • Open Access
7 Citations
3,087 Views
14 Pages

Association between Urinary BPA Substitutes and Precocious Puberty among Girls: A Single-Exposure and Mixed Exposure Approach from a Chinese Case—Control Study

  • Francis Manyori Bigambo,
  • Dandan Wang,
  • Jian Sun,
  • Xinliang Ding,
  • Xiuzhu Li,
  • Beibei Gao,
  • Di Wu,
  • Wei Gu,
  • Mingzhi Zhang and
  • Xu Wang

6 November 2023

There is an argument that BPA substitutes may have the same or more deleterious health effects as BPA due to their structural similarity. This study explored the association between urinary BPA substitutes and precocious puberty among girls by includ...

  • Article
  • Open Access
12 Citations
4,373 Views
16 Pages

20 January 2023

Background: There is limited research on the associations between serum nutritional biomarkers and mortality risk in patients with metabolic syndrome (MetS). Existing studies merely investigated the single-biomarker effect. Thus, this study aimed to...

  • Article
  • Open Access
10 Citations
8,586 Views
44 Pages

26 March 2025

Predicting innovation outcomes at the firm level continues to be an important but challenging goal for researchers and practitioners alike. In this study, multiple machine learning models, encompassing both ensemble-based and single-model approaches,...

  • Article
  • Open Access
2 Citations
2,025 Views
24 Pages

Cardiovascular diseases (CVDs) are the leading cause of mortality globally, accounting for approximately one-third of all deaths. Exposure to toxic metals poses significant risks to cardiovascular health, contributing to the development of CVDs. Esse...

  • Article
  • Open Access
12 Citations
3,388 Views
14 Pages

Association between Haematological Parameters and Exposure to a Mixture of Organophosphate and Neonicotinoid Insecticides among Male Farmworkers in Northern Thailand

  • Neeranuch Suwannarin,
  • Tippawan Prapamontol,
  • Tomohiko Isobe,
  • Yukiko Nishihama,
  • Ampica Mangklabruks,
  • Tawiwan Pantasri,
  • Somporn Chantara,
  • Warangkana Naksen and
  • Shoji F. Nakayama

Exposure to insecticides may result in various health problems. This study investigated the association between haematological parameters and exposure to a mixture of organophosphate (OP) and neonicotinoid (NEO) insecticides among male farmworkers in...

  • Article
  • Open Access
5 Citations
2,512 Views
18 Pages

26 February 2024

Herein, we explored the overall association between metal mixtures and lung functions in populations of varying ages and the relationship among the associated components. The 2007–2012 National Health and Nutrition Examination Survey data of 43...

  • Article
  • Open Access
7 Citations
4,607 Views
12 Pages

Assessment of Individual and Mixed Effects of Six Minerals on Thyroid Hormones in Chinese Pregnant Women

  • Simeng Gu,
  • Zhe Mo,
  • Zhijian Chen,
  • Xueqing Li,
  • Yujie Jiang,
  • Chenyang Liu,
  • Fanjia Guo,
  • Yahui Li,
  • Guangming Mao and
  • Xiaofeng Wang
  • + 1 author

3 February 2024

The biosynthesis of thyroid hormones is essential for brain and neurological development. It requires iodine as a key component but is also influenced by other nutrients. Evidence for the combined nutrient status in relation to thyroid hormones durin...

  • Article
  • Open Access
52 Citations
4,014 Views
13 Pages

SVM and ANN Modelling Approach for the Optimization of Membrane Permeability of a Membrane Rotating Biological Contactor for Wastewater Treatment

  • Sharjeel Waqas,
  • Noorfidza Yub Harun,
  • Nonni Soraya Sambudi,
  • Ushtar Arshad,
  • Nik Abdul Hadi Md Nordin,
  • Muhammad Roil Bilad,
  • Anwar Ameen Hezam Saeed and
  • Asher Ahmed Malik

23 August 2022

Membrane fouling significantly hinders the widespread application of membrane technology. In the current study, a support vector machine (SVM) and artificial neural networks (ANN) modelling approach was adopted to optimize the membrane permeability i...

  • Article
  • Open Access
3 Citations
2,456 Views
40 Pages

In this study, we focused on using microarray gene data from pancreatic sources to detect diabetes mellitus. Dimensionality reduction (DR) techniques were used to reduce the dimensionally high microarray gene data. DR methods like the Bessel function...

  • Article
  • Open Access
50 Citations
5,844 Views
22 Pages

11 December 2020

Applications of machine learning algorithms (MLAs) to modeling the adsorption efficiencies of different heavy metals have been limited by the adsorbate–adsorbent pair and the selection of specific MLAs. In the current study, adsorption efficien...

  • Article
  • Open Access
11 Citations
4,240 Views
21 Pages

28 April 2024

This study utilizes the National Health and Nutrition Examination Survey (NHANES) 2017–2018 data to explore the relationship between exposure to perfluoroalkyl substances (specifically perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic a...

  • Feature Paper
  • Article
  • Open Access
1,471 Views
20 Pages

AI-Driven Optimization for Efficient Public Bus Operations

  • Cheng-Yu Ku,
  • Chih-Yu Liu and
  • Ting-Yuan Wu

10 October 2025

Public transport bus services often experience financial inefficiencies due to high operational costs and unbalanced service allocation. To address these challenges, this study presents a machine learning-based framework aimed at optimizing financial...

  • Article
  • Open Access
13 Citations
3,571 Views
17 Pages

9 August 2022

Accurate prediction of the remaining useful life (RUL) of lithium–ion batteries is the focus of lithium–ion battery health management. To achieve high–precision RUL estimation of lithium–ion batteries, a novel RUL prediction model is proposed by comb...

  • Article
  • Open Access
14 Citations
2,918 Views
15 Pages

Association between Serum Level of Multiple Trace Elements and Esophageal Squamous Cell Carcinoma Risk: A Case–Control Study in China

  • Jingbing Zhang,
  • Geng Wang,
  • Anyan Huang,
  • Kexin Cao,
  • Wei Tan,
  • Hui Geng,
  • Xiaosheng Lin,
  • Fulan Zhan,
  • Kusheng Wu and
  • Caixia Liu
  • + 1 author

31 August 2022

We investigated the associations between multiple serum trace element levels and risk for esophageal squamous cell carcinoma (ESCC). A total of 185 ESCC patients and 191 healthy individuals were recruited in our study. The concentration of 13 trace e...

  • Article
  • Open Access
225 Views
32 Pages

15 January 2026

Reliable probabilistic wind speed forecasts are essential for integrating renewable energy into power grids and managing operational uncertainty. This study compares Quantile Regression Forests (QRF), Bayesian Additive Regression Trees (BART), and Ga...

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