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  • Review
  • Open Access
170 Citations
19,769 Views
33 Pages

Surface Plasmon Resonance (SPR) Sensor for Cancer Biomarker Detection

  • Sreyashi Das,
  • Ram Devireddy and
  • Manas Ranjan Gartia

17 March 2023

A biomarker is a physiological observable marker that acts as a stand-in and, in the best-case scenario, forecasts a clinically significant outcome. Diagnostic biomarkers are more convenient and cost-effective than directly measuring the ultimate cli...

  • Review
  • Open Access
160 Citations
11,611 Views
37 Pages

22 July 2024

The steady progress in consumer electronics, together with improvement in microflow techniques, nanotechnology, and data processing, has led to implementation of cost-effective, user-friendly portable devices, which play the role of not only gadgets...

  • Review
  • Open Access
104 Citations
38,164 Views
30 Pages

18 November 2024

Wearable biosensors are a fast-evolving topic at the intersection of healthcare, technology, and personalized medicine. These sensors, which are frequently integrated into clothes and accessories or directly applied to the skin, provide continuous, r...

  • Review
  • Open Access
103 Citations
9,946 Views
20 Pages

8 August 2023

Most agricultural land, as a result of climate change, experiences severe stress that significantly reduces agricultural yields. Crop sensing by imaging techniques allows early-stage detection of biotic or abiotic stress to avoid damage and significa...

  • Review
  • Open Access
95 Citations
34,270 Views
50 Pages

Advances in Respiratory Monitoring: A Comprehensive Review of Wearable and Remote Technologies

  • Diana Vitazkova,
  • Erik Foltan,
  • Helena Kosnacova,
  • Michal Micjan,
  • Martin Donoval,
  • Anton Kuzma,
  • Martin Kopani and
  • Erik Vavrinsky

6 February 2024

This article explores the importance of wearable and remote technologies in healthcare. The focus highlights its potential in continuous monitoring, examines the specificity of the issue, and offers a view of proactive healthcare. Our research descri...

  • Review
  • Open Access
93 Citations
7,358 Views
18 Pages

12 May 2023

Wide-ranging research efforts have been directed to prioritize scientific and technological inventions for healthcare monitoring. In recent years, the effective utilization of functional nanomaterials in various electroanalytical measurements realize...

  • Review
  • Open Access
91 Citations
14,136 Views
23 Pages

Strategies for Surface Design in Surface Plasmon Resonance (SPR) Sensing

  • Cristina-Virginia Topor,
  • Mihaela Puiu and
  • Camelia Bala

7 April 2023

Surface plasmon resonance (SPR) comprises several surface-sensitive techniques that enable the trace and ultra-trace detection of various analytes through affinity pairing. Although enabling label-free, sensitive detection and real-time monitoring, s...

  • Review
  • Open Access
90 Citations
17,136 Views
17 Pages

23 August 2023

Lateral flow tests are one of the most important types of paper-based point-of-care (POCT) diagnostic tools. It shows great potential as an implement for improving the rapid screening and management of infections in global pandemics or other potentia...

  • Review
  • Open Access
82 Citations
10,371 Views
38 Pages

Carbon Nanomaterials-Based Screen-Printed Electrodes for Sensing Applications

  • Rafael Matias Silva,
  • Alexsandra Dias da Silva,
  • Jéssica Rocha Camargo,
  • Bruna Santos de Castro,
  • Laís Muniz Meireles,
  • Patrícia Soares Silva,
  • Bruno Campos Janegitz and
  • Tiago Almeida Silva

3 April 2023

Electrochemical sensors consisting of screen-printed electrodes (SPEs) are recurrent devices in the recent literature for applications in different fields of interest and contribute to the expanding electroanalytical chemistry field. This is due to i...

  • Review
  • Open Access
81 Citations
6,706 Views
24 Pages

5 April 2023

This review highlights the recent advancements in the field of nanozymes and their applications in the development of point-of-care biosensors. The use of nanozymes as enzyme-mimicking components in biosensing systems has led to improved performance...

  • Review
  • Open Access
81 Citations
7,317 Views
23 Pages

27 January 2024

The integration of nanomaterials into sensor technologies not only poses challenges but also opens up promising prospects for future research. These challenges include assessing the toxicity of nanomaterials, scalability issues, and the seamless inte...

  • Review
  • Open Access
76 Citations
12,646 Views
38 Pages

18 May 2023

Molecular vibrations play a crucial role in physical chemistry and biochemistry, and Raman and infrared spectroscopy are the two most used techniques for vibrational spectroscopy. These techniques provide unique fingerprints of the molecules in a sam...

  • Review
  • Open Access
75 Citations
12,429 Views
44 Pages

9 January 2025

Surface Plasmon Resonance (SPR)-based biodetection systems have emerged as powerful tools for real-time, label-free biomolecular interaction analysis, revolutionizing fields such as diagnostics, drug discovery, and environmental monitoring. This revi...

  • Review
  • Open Access
75 Citations
15,295 Views
33 Pages

Biomarker Detection in Early Diagnosis of Cancer: Recent Achievements in Point-of-Care Devices Based on Paper Microfluidics

  • Bilge Asci Erkocyigit,
  • Ozge Ozufuklar,
  • Aysenur Yardim,
  • Emine Guler Celik and
  • Suna Timur

15 March 2023

Microfluidics is very crucial in lab-on-a-chip systems for carrying out operations in a large-scale laboratory environment on a single chip. Microfluidic systems are miniaturized devices in which the fluid behavior and control can be manipulated on a...

  • Review
  • Open Access
74 Citations
12,195 Views
34 Pages

26 June 2023

The technology of wearable medical equipment has advanced to the point where it is now possible to monitor the electrocardiogram and electromyogram comfortably at home. The transition from wet Ag/AgCl electrodes to various types of gel-free dry elect...

  • Review
  • Open Access
74 Citations
14,113 Views
48 Pages

7 November 2023

The promising field of organic electronics has ushered in a new era of biosensing technology, thus offering a promising frontier for applications in both medical diagnostics and environmental monitoring. This review paper provides a comprehensive ove...

  • Review
  • Open Access
73 Citations
10,468 Views
29 Pages

Recent Advancements of LSPR Fiber-Optic Biosensing: Combination Methods, Structure, and Prospects

  • Hongxin Zhang,
  • Xue Zhou,
  • Xuegang Li,
  • Pengqi Gong,
  • Yanan Zhang and
  • Yong Zhao

20 March 2023

Fiber-optic biosensors based on localized surface plasmon resonance (LSPR) have the advantages of great biocompatibility, label-free, strong stability, and real-time monitoring of various analytes. LSPR fiber-optic biosensors have attracted extensive...

  • Review
  • Open Access
72 Citations
11,490 Views
33 Pages

A Review on Photonic Sensing Technologies: Status and Outlook

  • Muhammad A. Butt,
  • Nikolay L. Kazanskiy,
  • Svetlana N. Khonina,
  • Grigory S. Voronkov,
  • Elizaveta P. Grakhova and
  • Ruslan V. Kutluyarov

22 May 2023

In contemporary science and technology, photonic sensors are essential. They may be made to be extremely resistant to some physical parameters while also being extremely sensitive to other physical variables. Most photonic sensors may be incorporated...

  • Article
  • Open Access
70 Citations
4,491 Views
16 Pages

Designing a Graphene Metasurface Organic Material Sensor for Detection of Organic Compounds in Wastewater

  • Khaled Aliqab,
  • Jacob Wekalao,
  • Meshari Alsharari,
  • Ammar Armghan,
  • Dhruvik Agravat and
  • Shobhit K. Patel

26 July 2023

In many fields, such as environmental monitoring, food safety, and medical diagnostics, the identification of organic compounds is essential. It is crucial to create exceptionally sensitive and selective sensors for the detection of organic compounds...

  • Review
  • Open Access
70 Citations
14,285 Views
23 Pages

27 March 2023

In comparison with traditional clinical diagnosis methods, field–effect transistor (FET)–based biosensors have the advantages of fast response, easy miniaturization and integration for high–throughput screening, which demonstrates t...

  • Review
  • Open Access
65 Citations
10,837 Views
30 Pages

Optical Fibre-Based Sensors—An Assessment of Current Innovations

  • Svetlana N. Khonina,
  • Nikolay L. Kazanskiy and
  • Muhammad A. Butt

22 August 2023

Optical fibre sensors are an essential subset of optical fibre technology, designed specifically for sensing and measuring several physical parameters. These sensors offer unique advantages over traditional sensors, making them gradually more valuabl...

  • Review
  • Open Access
65 Citations
12,406 Views
36 Pages

10 August 2023

The increasing research and rapid developments in the field of exosomes provide insights into their role and significance in human health. Exosomes derived from various sources, such as mesenchymal stem cells, cardiac cells, and tumor cells, to name...

  • Review
  • Open Access
65 Citations
14,427 Views
32 Pages

Flexible and Wearable Biosensors for Monitoring Health Conditions

  • Zhimin Song,
  • Shu Zhou,
  • Yanxia Qin,
  • Xiangjiao Xia,
  • Yanping Sun,
  • Guanghong Han,
  • Tong Shu,
  • Liang Hu and
  • Qiang Zhang

7 June 2023

Flexible and wearable biosensors have received tremendous attention over the past decade owing to their great potential applications in the field of health and medicine. Wearable biosensors serve as an ideal platform for real-time and continuous heal...

  • Review
  • Open Access
64 Citations
31,135 Views
27 Pages

Organ-on-a-chip (OOC) is an emerging technology that simulates an artificial organ within a microfluidic cell culture chip. Current cell biology research focuses on in vitro cell cultures due to various limitations of in vivo testing. Unfortunately,...

  • Review
  • Open Access
63 Citations
5,619 Views
52 Pages

Macromolecule–Nanoparticle-Based Hybrid Materials for Biosensor Applications

  • Giddaerappa Kuntoji,
  • Naseem Kousar,
  • Shivalingayya Gaddimath and
  • Lokesh Koodlur Sannegowda

28 May 2024

Biosensors function as sophisticated devices, converting biochemical reactions into electrical signals. Contemporary emphasis on developing biosensor devices with refined sensitivity and selectivity is critical due to their extensive functional capab...

  • Review
  • Open Access
63 Citations
9,386 Views
37 Pages

Immobilization of Enzyme Electrochemical Biosensors and Their Application to Food Bioprocess Monitoring

  • Ganchao Sun,
  • Xiaobo Wei,
  • Dianping Zhang,
  • Liben Huang,
  • Huiyan Liu and
  • Haitian Fang

17 September 2023

Electrochemical biosensors based on immobilized enzymes are among the most popular and commercially successful biosensors. The literature in this field suggests that modification of electrodes with nanomaterials is an excellent method for enzyme immo...

  • Review
  • Open Access
60 Citations
9,964 Views
36 Pages

27 March 2023

Electrochemical biosensors are superior technologies that are used to detect or sense biologically and environmentally significant analytes in a laboratory environment, or even in the form of portable handheld or wearable electronics. Recently, impri...

  • Review
  • Open Access
59 Citations
10,585 Views
32 Pages

Novel Approaches to Enzyme-Based Electrochemical Nanobiosensors

  • Nur Melis Kilic,
  • Sima Singh,
  • Gulsu Keles,
  • Stefano Cinti,
  • Sevinc Kurbanoglu and
  • Dilek Odaci

5 June 2023

Electrochemistry is a genuinely interdisciplinary science that may be used in various physical, chemical, and biological domains. Moreover, using biosensors to quantify biological or biochemical processes is critical in medical, biological, and biote...

  • Review
  • Open Access
58 Citations
9,070 Views
31 Pages

Recent Advances in Biomolecular Detection Based on Aptamers and Nanoparticles

  • Ruiting Xu,
  • Leixin Ouyang,
  • Heyi Chen,
  • Ge Zhang and
  • Jiang Zhe

13 April 2023

The fast, accurate detection of biomolecules, ranging from nucleic acids and small molecules to proteins and cellular secretions, plays an essential role in various biomedical applications. These include disease diagnostics and prognostics, environme...

  • Review
  • Open Access
57 Citations
8,919 Views
28 Pages

Molecularly Imprinted Polymer-Based Electrochemical Sensors for the Diagnosis of Infectious Diseases

  • Greta Pilvenyte,
  • Vilma Ratautaite,
  • Raimonda Boguzaite,
  • Simonas Ramanavicius,
  • Chien-Fu Chen,
  • Roman Viter and
  • Arunas Ramanavicius

5 June 2023

The appearance of biological molecules, so-called biomarkers in body fluids at abnormal concentrations, is considered a good tool for detecting disease. Biomarkers are usually looked for in the most common body fluids, such as blood, nasopharyngeal f...

  • Review
  • Open Access
56 Citations
9,124 Views
23 Pages

Advancement in Paper-Based Electrochemical Biosensing and Emerging Diagnostic Methods

  • Stephen Rathinaraj Benjamin,
  • Fábio de Lima,
  • Valter Aragão do Nascimento,
  • Geanne Matos de Andrade and
  • Reinaldo Barreto Oriá

28 June 2023

The utilization of electrochemical detection techniques in paper-based analytical devices (PADs) has revolutionized point-of-care (POC) testing, enabling the precise and discerning measurement of a diverse array of (bio)chemical analytes. The applica...

  • Review
  • Open Access
55 Citations
13,126 Views
28 Pages

Smart Contact Lenses—A Step towards Non-Invasive Continuous Eye Health Monitoring

  • Nikolay L. Kazanskiy,
  • Svetlana N. Khonina and
  • Muhammad A. Butt

18 October 2023

According to the age-old adage, while eyes are often considered the gateway to the soul, they might also provide insights into a more pragmatic aspect of our health: blood sugar levels. This potential breakthrough could be realized through the develo...

  • Review
  • Open Access
55 Citations
17,135 Views
10 Pages

26 March 2024

The resazurin assay, also known as the Alamar Blue assay, stands as a cornerstone technique in cell biology, microbiology, and drug development. It assesses the viability of cells through the conversion of resazurin into highly fluorescent resorufin....

  • Review
  • Open Access
55 Citations
8,592 Views
20 Pages

Terahertz Metamaterials for Biosensing Applications: A Review

  • Wu Zhang,
  • Jiahan Lin,
  • Zhengxin Yuan,
  • Yanxiao Lin,
  • Wenli Shang,
  • Lip Ket Chin and
  • Meng Zhang

21 December 2023

In recent decades, THz metamaterials have emerged as a promising technology for biosensing by extracting useful information (composition, structure and dynamics) of biological samples from the interaction between the THz wave and the biological sampl...

  • Review
  • Open Access
55 Citations
8,906 Views
37 Pages

Advances in Tapered Optical Fiber Sensor Structures: From Conventional to Novel and Emerging

  • Wen Zhang,
  • Xianzheng Lang,
  • Xuecheng Liu,
  • Guoru Li,
  • Ragini Singh,
  • Bingyuan Zhang and
  • Santosh Kumar

12 June 2023

Optical fiber sensors based on tapered optical fiber (TOF) structure have attracted a considerable amount of attention from researchers due to the advantages of simple fabrication, high stability, and diverse structures, and have great potential for...

  • Review
  • Open Access
53 Citations
11,412 Views
28 Pages

Revolutionizing Precision Medicine: Exploring Wearable Sensors for Therapeutic Drug Monitoring and Personalized Therapy

  • Yuqiao Liu,
  • Junmin Li,
  • Shenghao Xiao,
  • Yanhui Liu,
  • Mingxia Bai,
  • Lixiu Gong,
  • Jiaqian Zhao and
  • Dajing Chen

12 July 2023

Precision medicine, particularly therapeutic drug monitoring (TDM), is essential for optimizing drug dosage and minimizing toxicity. However, current TDM methods have limitations, including the need for skilled operators, patient discomfort, and the...

  • Communication
  • Open Access
53 Citations
3,652 Views
14 Pages

Bisphenol A Imprinted Electrochemical Sensor Based on Graphene Quantum Dots with Boron Functionalized g-C3N4 in Food Samples

  • Haci Ahmet Deveci,
  • Müge Mavioğlu Kaya,
  • İnan Kaya,
  • Bahar Bankoğlu Yola,
  • Necip Atar and
  • Mehmet Lütfi Yola

12 July 2023

A molecular imprinted electrochemical sensor based on boron-functionalized graphitic carbon nitride (B-g-C3N4) and graphene quantum dots (GQDs) was presented for selective determination of bisphenol A (BPA). In particular, by combining the selectivit...

  • Review
  • Open Access
51 Citations
9,911 Views
26 Pages

Advanced Textile-Based Wearable Biosensors for Healthcare Monitoring

  • Sheng Li,
  • Huan Li,
  • Yongcai Lu,
  • Minhao Zhou,
  • Sai Jiang,
  • Xiaosong Du and
  • Chang Guo

27 September 2023

With the innovation of wearable technology and the rapid development of biosensors, wearable biosensors based on flexible textile materials have become a hot topic. Such textile-based wearable biosensors promote the development of health monitoring,...

  • Review
  • Open Access
49 Citations
9,566 Views
24 Pages

Emerging Applications of Nanobiosensors in Pathogen Detection in Water and Food

  • Hiram Martin Valenzuela-Amaro,
  • Alberto Aguayo-Acosta,
  • Edgar Ricardo Meléndez-Sánchez,
  • Orlando de la Rosa,
  • Perla Guadalupe Vázquez-Ortega,
  • Mariel Araceli Oyervides-Muñoz,
  • Juan Eduardo Sosa-Hernández and
  • Roberto Parra-Saldívar

11 October 2023

Food and waterborne illnesses are still a major concern in health and food safety areas. Every year, almost 0.42 million and 2.2 million deaths related to food and waterborne illness are reported worldwide, respectively. In foodborne pathogens, bacte...

  • Perspective
  • Open Access
49 Citations
6,034 Views
15 Pages

A Short Review on Miniaturized Biosensors for the Detection of Nucleic Acid Biomarkers

  • Madhusudan B. Kulkarni,
  • Narasimha H. Ayachit and
  • Tejraj M. Aminabhavi

22 March 2023

Even today, most biomarker testing is executed in centralized, dedicated laboratories using bulky instruments, automated analyzers, and increased analysis time and expenses. The development of miniaturized, faster, low-cost microdevices is immensely...

  • Article
  • Open Access
49 Citations
4,683 Views
16 Pages

30 April 2023

In this work, we prepared a novel electrochemical sensor for the detection of tramadol based on a UiO-66-NH2 metal–organic framework (UiO-66-NH2 MOF)/third-generation poly(amidoamine) dendrimer (G3-PAMAM dendrimer) nanocomposite drop-cast onto...

  • Review
  • Open Access
49 Citations
7,499 Views
28 Pages

Advancing Healthcare: Synergizing Biosensors and Machine Learning for Early Cancer Diagnosis

  • Mahtab Kokabi,
  • Muhammad Nabeel Tahir,
  • Darshan Singh and
  • Mehdi Javanmard

13 September 2023

Cancer is a fatal disease and a significant cause of millions of deaths. Traditional methods for cancer detection often have limitations in identifying the disease in its early stages, and they can be expensive and time-consuming. Since cancer typica...

  • Review
  • Open Access
48 Citations
8,938 Views
39 Pages

Electrochemical Biosensors for the Detection of Antibiotics in Milk: Recent Trends and Future Perspectives

  • Baljit Singh,
  • Abhijnan Bhat,
  • Lesa Dutta,
  • Kumari Riya Pati,
  • Yaroslav Korpan and
  • Isha Dahiya

1 September 2023

Antibiotics have emerged as ground-breaking medications for the treatment of infectious diseases, but due to the excessive use of antibiotics, some drugs have developed resistance to microorganisms. Because of their structural complexity, most antibi...

  • Review
  • Open Access
47 Citations
8,593 Views
39 Pages

Recent Advancements in MXene-Based Biosensors for Health and Environmental Applications—A Review

  • Ashraf Ali,
  • Sanjit Manohar Majhi,
  • Lamia A. Siddig,
  • Abdul Hakeem Deshmukh,
  • Hongli Wen,
  • Naser N. Qamhieh,
  • Yaser E. Greish and
  • Saleh T. Mahmoud

12 October 2024

Owing to their unique physicochemical properties, MXenes have emerged as promising materials for biosensing applications. This review paper comprehensively explores the recent advancements in MXene-based biosensors for health and environmental applic...

  • Review
  • Open Access
47 Citations
8,986 Views
61 Pages

Electrochemical Wearable Biosensors and Bioelectronic Devices Based on Hydrogels: Mechanical Properties and Electrochemical Behavior

  • Mohsen Saeidi,
  • Hossein Chenani,
  • Mina Orouji,
  • MahsaSadat Adel Rastkhiz,
  • Nafiseh Bolghanabadi,
  • Shaghayegh Vakili,
  • Zahra Mohamadnia,
  • Amir Hatamie and
  • Abdolreza (Arash) Simchi

15 August 2023

Hydrogel-based wearable electrochemical biosensors (HWEBs) are emerging biomedical devices that have recently received immense interest. The exceptional properties of HWEBs include excellent biocompatibility with hydrophilic nature, high porosity, ta...

  • Review
  • Open Access
47 Citations
8,825 Views
34 Pages

Aptamer-Based Point-of-Care Devices: Emerging Technologies and Integration of Computational Methods

  • Yusuf Aslan,
  • Maryam Atabay,
  • Hussain Kawsar Chowdhury,
  • Ilgım Göktürk,
  • Yeşeren Saylan and
  • Fatih Inci

22 May 2023

Recent innovations in point-of-care (POC) diagnostic technologies have paved a critical road for the improved application of biomedicine through the deployment of accurate and affordable programs into resource-scarce settings. The utilization of anti...

  • Review
  • Open Access
47 Citations
6,732 Views
27 Pages

Electrochemically Synthesized MIP Sensors: Applications in Healthcare Diagnostics

  • Akinrinade George Ayankojo,
  • Jekaterina Reut and
  • Vitali Syritski

30 January 2024

Early-stage detection and diagnosis of diseases is essential to the prompt commencement of treatment regimens, curbing the spread of the disease, and improving human health. Thus, the accurate detection of disease biomarkers through the development o...

  • Review
  • Open Access
46 Citations
9,754 Views
40 Pages

Recent Advances in Batteryless NFC Sensors for Chemical Sensing and Biosensing

  • Antonio Lazaro,
  • Ramon Villarino,
  • Marc Lazaro,
  • Nicolau Canellas,
  • Beatriz Prieto-Simon and
  • David Girbau

31 July 2023

This article reviews the recent advances in the field of batteryless near-field communication (NFC) sensors for chemical sensing and biosensing. The commercial availability of low-cost commercial NFC integrated circuits (ICs) and their massive integr...

  • Review
  • Open Access
46 Citations
4,913 Views
21 Pages

Nanomaterials and Their Recent Applications in Impedimetric Biosensing

  • Zala Štukovnik,
  • Regina Fuchs-Godec and
  • Urban Bren

22 September 2023

Impedimetric biosensors measure changes in the electrical impedance due to a biochemical process, typically the binding of a biomolecule to a bioreceptor on the sensor surface. Nanomaterials can be employed to modify the biosensor’s surface to...

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Biosensors - ISSN 2079-6374