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Biosensors 2018, 8(3), 80;

Surface Plasmon Resonance Optical Sensor: A Review on Light Source Technology

Research Center for Electronics and Telecommunications, Indonesian Institute of Sciences, Bandung 40135, Indonesia
Department of Electronics Engineering, Chang Gung University, Taoyuan 33302, Taiwan
Research Unit for Clean Technology, Indonesian Institute of Sciences, Bandung 40135, Indonesia
Division of Pediatric Infectious Disease, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan
Department of Materials Engineering, Ming Chi University of Technology, New Taipei City 24301, Taiwan
Authors to whom correspondence should be addressed.
Received: 23 July 2018 / Revised: 22 August 2018 / Accepted: 22 August 2018 / Published: 26 August 2018
(This article belongs to the Special Issue Immunoanalytical Tool with Electrochemical and Optical Detection)
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The notion of surface plasmon resonance (SPR) sensor research emerged more than eight decades ago from the first observed phenomena in 1902 until the first introduced principles for gas sensing and biosensing in 1983. The sensing platform has been hand-in-hand with the plethora of sensing technology advancement including nanostructuring, optical technology, fluidic technology, and light source technology, which contribute to substantial progress in SPR sensor evolution. Nevertheless, the commercial products of SPR sensors in the market still require high-cost investment, component, and operation, leading to unaffordability for their implementation in a low-cost point of care (PoC) or laboratories. In this article, we present a comprehensive review of SPR sensor development including the state of the art from a perspective of light source technology trends. Based on our review, the trend of SPR sensor configurations, as well as its methodology and optical designs are strongly influenced by the development of light source technology as a critical component. These simultaneously offer new underlying principles of SPR sensor towards miniaturization, portability, and disposability features. The low-cost solid-state light source technology, such as laser diode, light-emitting diode (LED), organic light emitting diode (OLED) and smartphone display have been reported as proof of concept for the future of low-cost SPR sensor platforms. Finally, this review provides a comprehensive overview, particularly for SPR sensor designers, including emerging engineers or experts in this field. View Full-Text
Keywords: SPR; sensor; biosensor; light source; optical device SPR; sensor; biosensor; light source; optical device

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Prabowo, B.A.; Purwidyantri, A.; Liu, K.-C. Surface Plasmon Resonance Optical Sensor: A Review on Light Source Technology. Biosensors 2018, 8, 80.

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