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732 Results Found

  • Article
  • Open Access
2 Citations
2,457 Views
15 Pages

7 November 2022

It is difficult to adapt the traditional section margin distribution method to the power system with a high proportion of renewable energy generation (REG). This paper proposes a section margin allocation method of REG clusters considering the random...

  • Communication
  • Open Access
2 Citations
1,889 Views
8 Pages

Improved Rate of Negative Margins for Inflammatory Breast Cancer Using Intraoperative Frozen Section Analysis

  • Joshua Kong,
  • Sudeshna Bandyopadhyay,
  • Wei Chen,
  • Faisal Al-Mufarrej,
  • Lydia Choi and
  • Mary A. Kosir

16 September 2023

Background: Inflammatory breast cancer (IBC) is a rare and aggressive form of breast cancer with a poor survival rate. Modified radical mastectomy (MRM) with negative pathologic margins is critical for improved survival. We aim to study the potential...

  • Article
  • Open Access
8 Citations
4,094 Views
11 Pages

Recurrence of Basal Cell Carcinoma Treated with Surgical Excision and Histopathological Analysis with Frozen Section Technique with Complete Margin Control (CMC-FS): A 15-Year Experience of a Reference Center

  • Alessandra Di Maria,
  • Gianmaria Barone,
  • Vanessa Ferraro,
  • Costanza Tredici,
  • Sofia Manara,
  • Camilla De Carlo,
  • Alessandro Gaeta and
  • Filippo Confalonieri

28 July 2023

Background: Basal cell carcinoma (BCC) is the most common type of eyelid malignancy and it is considered to be dangerous due to its proximity to functionally essential organs. Early diagnosis and complete excision of the primary lesion are crucial to...

  • Review
  • Open Access
1,475 Views
22 Pages

5 November 2025

Background/Objectives: Breast cancer is the most prevalent neoplasm in women. Improved screening and systemic therapies have allowed more patients to choose breast-conserving surgery over mastectomy. However, preserving glandular tissue while achievi...

  • Article
  • Open Access
1 Citations
1,552 Views
15 Pages

Do Family Physicians’ Recommendations for Influenza and Pneumococcal Vaccines Impact the Elderly Aged ≥60 Years? A Cross-Sectional Study in Six Chinese Cities

  • Yuxing Wang,
  • Jianing Dai,
  • Shuai Yuan,
  • Ying Chen,
  • Zhujiazi Zhang,
  • Ling Zhu,
  • Gang Liu,
  • Qiang Zeng,
  • Qian Qiu and
  • Lili You
  • + 2 authors

21 August 2025

Background: Influenza vaccine and pneumococcal vaccine are essential to protect the health of older adults. This study focuses on the impact of family physicians’ recommendations on influenza and pneumococcal vaccine uptake among urban Chinese...

  • Article
  • Open Access
4 Citations
3,582 Views
21 Pages

Despite advances in treatment, recurrence rates in oral squamous cell carcinoma (OSCC) remain high. Prognostic outcomes vary in terms of local recurrence, metastasis, and overall survival. A retrospective cohort analysis was conducted on OSCC patient...

  • Review
  • Open Access
3 Citations
4,084 Views
18 Pages

The Value of Micro-CT in the Diagnosis of Lung Carcinoma: A Radio-Histopathological Perspective

  • Serpil Dizbay Sak,
  • Selim Sevim,
  • Arda Buyuksungur,
  • Ayten Kayı Cangır and
  • Kaan Orhan

20 October 2023

Micro-computed tomography (micro-CT) is a relatively new imaging modality and the three-dimensional (3D) images obtained via micro-CT allow researchers to collect both quantitative and qualitative information on various types of samples. Micro-CT cou...

  • Article
  • Open Access
28 Citations
3,983 Views
10 Pages

Intraoperative Assessment of Tumor Margins in Tissue Sections with Hyperspectral Imaging and Machine Learning

  • David Pertzborn,
  • Hoang-Ngan Nguyen,
  • Katharina Hüttmann,
  • Jonas Prengel,
  • Günther Ernst,
  • Orlando Guntinas-Lichius,
  • Ferdinand von Eggeling and
  • Franziska Hoffmann

29 December 2022

The intraoperative assessment of tumor margins of head and neck cancer is crucial for complete tumor resection and patient outcome. The current standard is to take tumor biopsies during surgery for frozen section analysis by a pathologist after H&...

  • Article
  • Open Access
1,148 Views
12 Pages

7 August 2025

Background/Objectives: To compare the marginal integrity of sectional non-invasive laminate veneers versus sectional minimally invasive laminate veneers. Methods: A total of eighty (80) intact maxillary and mandibular frontal teeth (central incisors)...

  • Feature Paper
  • Article
  • Open Access
3 Citations
6,100 Views
52 Pages

We investigate the marginal predictive content of small versus large jump variation, when forecasting one-week-ahead cross-sectional equity returns, building on Bollerslev et al. (2020). We find that sorting on signed small jump variation leads to gr...

  • Communication
  • Open Access
2 Citations
3,308 Views
8 Pages

Alteration of Tissue Marking Dyes Depends on Used Chromogen during Immunohistochemistry

  • Selina Kiefer,
  • Julia Huber,
  • Hannah Füllgraf,
  • Kristin Sörensen,
  • Agnes Csanadi,
  • Maren Nicole Stillger,
  • Martin Werner,
  • Hans-Eckart Schaefer,
  • Peter Bronsert and
  • Konrad Aumann

8 April 2021

Pathological biopsy protocols require tissue marking dye (TMD) for orientation. In some cases (e.g., close margin), additional immunohistochemical analyses can be necessary. Therefore, the correlation between the applied TMD during macroscopy and the...

  • Systematic Review
  • Open Access
15 Citations
3,071 Views
21 Pages

Assisted Reproductive Technique and Abnormal Cord Insertion: A Systematic Review and Meta-Analysis

  • Shinya Matsuzaki,
  • Yutaka Ueda,
  • Satoko Matsuzaki,
  • Yoshikazu Nagase,
  • Mamoru Kakuda,
  • Misooja Lee,
  • Michihide Maeda,
  • Hiroki Kurahashi,
  • Harue Hayashida and
  • Shoji Kamiura
  • + 2 authors

Abnormal cord insertion (ACI) is associated with adverse obstetric outcomes; however, the relationship between ACI and assisted reproductive technology (ART) has not been examined in a meta-analysis. This study examines the association between ACI an...

  • Article
  • Open Access
3 Citations
1,780 Views
9 Pages

Association of the Specimen and Tumor Bed Margin Status with Local Recurrence and Survival in Open Partial Laryngectomy

  • Rogério Aparecido Dedivitis,
  • Leandro Luongo de Matos,
  • Mario Augusto Ferrari de Castro and
  • Luiz Paulo Kowalski

24 April 2024

Background/Objectives: Positive margins are associated with locoregional recurrence in early laryngeal cancer. The aim of this study was to evaluate the impacts of specimen-driven (ex vivo) positive margins on patients with early-stage laryngeal canc...

  • Article
  • Open Access
7 Citations
3,800 Views
12 Pages

8 May 2019

In this study, we investigate direct current (DC)/alternating current (AC) characteristic variability induced by work function fluctuation (WKF) with respect to different nanosized metal grains and the variation of aspect ratios (ARs) of channel cros...

  • Article
  • Open Access
323 Views
15 Pages

5 January 2026

Background: There are approximately 5.4 M basal cell (BCC) and squamous cell (SCC) carcinomas diagnosed each year, and the number is increasing. Currently, the gold standard for skin cancer diagnosis is histopathology, which requires the surgical exc...

  • Article
  • Open Access
15 Citations
5,851 Views
12 Pages

Factors Associated with Maternal Deaths in a Hard-To-Reach Marginalized Rural Community of Bangladesh: A Cross-Sectional Study

  • Animesh Biswas,
  • Abdul Halim,
  • Abu Sayeed Md. Abdullah,
  • Fazlur Rahman and
  • Sathyanaraynan Doraiswamy

Every year in Bangladesh, approximately 5200 mothers die (172 maternal deaths/100,000 live births) due to maternal complications. The death rate is much higher in hard-to-reach areas and underprivileged communities, such as Bangladesh’s tea gar...

  • Article
  • Open Access
5 Citations
4,290 Views
11 Pages

Adolescence (10–19 years) is marked by many physiological changes and is vulnerable to health and nutritional problems. Adolescence, particularly, early adolescence is inadequately addressed in our national surveys. The present study aimed to assess...

  • Article
  • Open Access
2 Citations
1,363 Views
16 Pages

Effect of Heat Exchange Area Margins on Thermal Characteristics of the Heat Exchange System in the Pressurized Water Test Loop during Fuel Assembly Irradiation

  • Junping Si,
  • Guang Zhao,
  • Yun Wang,
  • Sheng Sun,
  • Mingyan Tong,
  • Wei Zhu,
  • Jin Lei,
  • Jinkang Cheng,
  • Yueyan Song and
  • Mengkang Lu

6 August 2024

The performance of heat exchangers in the pressurized water test loop is a critical factor in ensuring the achievement of irradiation parameters for fuel assemblies and the safety of experimental operations. The effect of the heat exchange area margi...

  • Article
  • Open Access
7 Citations
2,356 Views
17 Pages

Metal Toxicity across Different Thallus Sections of the Green Macroalga, Ulva australis

  • Hojun Lee,
  • Geonhee Kim,
  • Stephen Depuydt,
  • Kisik Shin,
  • Taejun Han and
  • Jihae Park

22 June 2023

We aimed to identify functional differences between different sections of the thallus of Ulva australis and develop tissue-endpoint combinations to assess the toxicity of six metals (i.e., Ag, As, Cd, Cr, Cu, and Ni). EC50 values for these metals in...

  • Article
  • Open Access
148 Views
18 Pages

Characteristics and Hydrocarbon Generation Potential of Permian Source Rocks in the Yining Sag, Ili Basin, Western China

  • Xiangcan Sun,
  • Kunpeng Jiang,
  • Li Yi,
  • Lei Wen,
  • Xingui Zhou,
  • Youxing Yang,
  • Zhongkai Bai,
  • Kun Yuan,
  • Yi Chen and
  • Zhichao Sun

26 January 2026

This study is based on field observations and sample collections from the Panjinbulak, Qiongbulak, and Qunjisayi outcrops in the Yining Sag of the Ili Basin. Using organic geochemical analysis methods, the characteristics and hydrocarbon generation p...

  • Article
  • Open Access
5 Citations
2,296 Views
9 Pages

Retrospective Cohort Study of Practical Applications of Paramagnetic Seed Localisation in Breast Carcinoma and Other Malignancies

  • Céline Clement,
  • Lieve Schops,
  • Ines Nevelsteen,
  • Soetkin Thijssen,
  • Chantal Van Ongeval,
  • Machteld Keupers,
  • Renate Prevos,
  • Valerie Celis,
  • Patrick Neven and
  • Ann Smeets
  • + 2 authors

16 December 2022

(1) Background: Paramagnetic seeds are a safe alternative for the wire-guided localisation of non-palpable breast lesions, but can also be applied for non-breast lesions. This study presents the experience with a paramagnetic seed, MagSeed® (Endo...

  • Article
  • Open Access
8 Citations
2,914 Views
15 Pages

New Tumor Budding Evaluation in Head and Neck Squamous Cell Carcinomas

  • Claudio Cacchi,
  • Henrike J. Fischer,
  • Kai Wermker,
  • Ashkan Rashad,
  • Danny D. Jonigk,
  • Frank Hölzle and
  • Maurice Klein

30 January 2024

Background: Tumor budding (TB) is a histomorphological characteristic of the tumor invasion front and it has an impact on the tumor outcome prediction for head and neck squamous cell carcinoma (HNSCC) aetiopathology. Patients and methods: The average...

  • Article
  • Open Access
408 Views
11 Pages

Staged Reconstruction Is Not Necessary Following Oncologic Resection of Superficial Myxofibrosarcoma

  • Leilani Garayua-Cruz,
  • Samuel E. Broida,
  • Mikaela H. Sullivan,
  • Andrew L. Folpe,
  • Meng X. Welliver,
  • Katie N. Lee,
  • Brittany L. Siontis,
  • Steven I. Robinson,
  • Thanh P. Ho and
  • Matthew T. Houdek
  • + 4 authors

12 November 2025

Background: Myxofibrosarcomas are notoriously highly infiltrative soft-tissue sarcomas, making negative surgical margins difficult to obtain. Recently, vacuum-assisted closure (VAC) is used to delay wound closure until a negative margin has been achi...

  • Article
  • Open Access
1 Citations
3,121 Views
14 Pages

Evaluation of the Marginal Adaptation of Two Hydraulic Calcium Silicate Cements Used in Apical Plugs: An In Vitro Study

  • Sara Filipe,
  • José Pedro Martinho,
  • Siri Paulo,
  • Catarina Carvalho,
  • Ana Coelho,
  • Inês Amaro,
  • Eunice Carrilho,
  • Anabela Paula,
  • Carlos Miguel Marto and
  • Manuel Marques Ferreira
  • + 3 authors

5 January 2024

Background: The emergence of new hydraulic calcium silicate cements has revolutionized endodontics, addressing the limitations of mineral trioxide aggregate (MTA). The aim of this study is to assess and compare the marginal adaptation of two calcium...

  • Article
  • Open Access
13 Citations
3,265 Views
11 Pages

29 September 2021

In the blood flow through microvessels, platelets show high concentrations near the vessel wall. This phenomenon is called margination of platelets and is closely associated with hemostasis and thrombosis. In the present study, we conducted in vitro...

  • Article
  • Open Access
13 Citations
4,756 Views
18 Pages

6 March 2022

Red blood cells flow near the axis in a small vessel, known as axial accumulation. This causes a region called the cell-free layer, which does not contain red blood cells near the wall. Then, small particles such as platelets come out to the cell-fre...

  • Correction
  • Open Access
1 Citations
3,703 Views
3 Pages

21 March 2019

Due to a coding error the marginal likelihoods have not been correctly calculated for the empirical example and thus the Bayes Factors following from these marginal likelihoods are incorrect. The corrections required occur in Section 3.2 and in two p...

  • Article
  • Open Access
1 Citations
6,397 Views
24 Pages

This study examined the relationship between margin trading and cryptocurrency investment using data from the 2018 and 2021 waves of the National Financial Capability Study (NFCS) Investor Survey. Guided by behavioral finance theory, which suggests t...

  • Article
  • Open Access
7 Citations
6,503 Views
17 Pages

Geomats Used to Control Erosion on Reservoir Margins in Brazilian Hydroelectric Power Plants

  • Marta Pereira da Luz,
  • Maria Alejandra Aparicio Ardila,
  • Ricardo D. dos Santos Junior,
  • Clever A. Valentin,
  • Marlon S. Schliewe,
  • Arnaldo T. Coelho and
  • Jefferson Lins da Silva

21 May 2021

Erosion on reservoir margins causes losses in the production of energy in Hydroelectric Power Plants (HPPs), making it necessary to implement control techniques that ensure the reduction in sediment deposits inside reservoirs. Among these techniques,...

  • Article
  • Open Access
6 Citations
3,663 Views
18 Pages

12 February 2020

The relationship between the average annual collapse probability and collapse safety margin of structures is identified to evaluate structural collapse performance quantitatively. A method is then proposed to determine the acceptable collapse margin...

  • Article
  • Open Access
101 Citations
8,377 Views
17 Pages

A Comparison Study of Marginal and Internal Fit Assessment Methods for Fixed Dental Prostheses

  • Keunbada Son,
  • Sangbong Lee,
  • Seok Hyon Kang,
  • Jaeseok Park,
  • Kyu-Bok Lee,
  • Mansik Jeon and
  • Byoung-Ju Yun

Numerous studies have previously evaluated the marginal and internal fit of fixed prostheses; however, few reports have performed an objective comparison of the various methods used for their assessment. The purpose of this study was to compare five...

  • Communication
  • Open Access
13 Citations
3,350 Views
6 Pages

19 November 2021

Measurements of cross-sections of charge exchange between hydrogen atoms and low energy protons (down to the energy ~10 eV) revealed a noticeable discrepancy with previous theories. The experimental cross-sections were systematically slightly higher—...

  • Article
  • Open Access
462 Views
15 Pages

Assessment of Tumor Margin and Heterogeneity of Colorectal Cancer Using Imaging Mass Spectrometry and Image Segmentation

  • Bojan Trogrlić,
  • Ana Bednjanić,
  • Borna Kovačić,
  • Zrinka Požgain,
  • Dario Mandić,
  • Magdalena Kratofil,
  • Jasmina Rajc,
  • Željko Debeljak and
  • Ilijan Tomaš

3 January 2026

Background/Objectives: There is an increasing need for methods that provide improved insight into the molecular basis of colorectal cancer (CRC) and thus a better understanding of its morphological heterogeneity. The objectives of this study were to...

  • Article
  • Open Access
7 Citations
4,046 Views
13 Pages

30 March 2023

(1) Background: The use of high-performance polymers for fixed restorations requires additional studies regarding their adaptability and processing with CAD/CAM technology. This in vitro study aims to assess the marginal and internal fit of PEEK and...

  • Article
  • Open Access
357 Views
17 Pages

In Vitro Evaluation of the Effect of NaOCl Deproteinization of MIH-Affected Hard Dental Tissue on the Marginal Integrity of a Glass Hybrid Material

  • Agata Ćwiklińska,
  • Joanna Szczepańska,
  • Joanna Nowak,
  • Sylwia Majewska-Beśka and
  • Agnieszka Bruzda-Zwiech

7 January 2026

The enamel of teeth affected by Molar–Incisor Hypomineralization (MIH) has been reported to have a higher protein content. Though a glass hybrid is recommended for restoring teeth with MIH in children, there is a lack of in vitro research on th...

  • Article
  • Open Access
10 Citations
2,992 Views
17 Pages

20 May 2023

In the present study, the impact of cutting-edge microgeometry on the cutting forces in the finish milling of a 7075-aluminium alloy was analysed. The influence of selected values of the rounding radius of cutting edge, and the size of the margin wid...

  • Article
  • Open Access
6 Citations
3,516 Views
7 Pages

16 May 2021

Background: This study compared the marginal gap (MG) and absolute marginal discrepancy (AMD) of computer-aided design and computer-aided manufacturing (CAD–CAM) used in open systems (OSs) and closed systems (CSs) for producing monolithic zirconia-re...

  • Article
  • Open Access
1 Citations
1,946 Views
21 Pages

To fully harness the design development potential of plastic angle sections, this study employs a theoretical analysis approach to examine the plastic behavior of equal angle sections subjected to axial force and biaxial bending. Based on the simplif...

  • Article
  • Open Access
12 Citations
1,336 Views
26 Pages

25 February 2025

The relevant value standards for reserved deformation of tunnels with different types of loess soil are not yet perfect. Through mathematical statistics, literature research, and other methods, 148 monitoring sections of loess tunnels with different...

  • Article
  • Open Access
8 Citations
7,310 Views
23 Pages

A low power adaptive digital baseband architecture is presented for a low-IF receiver of IEEE 802.15.4-2006. The digital section’s sampling frequency and bit width are used as knobs to reduce the power under favorable signal and interference scenario...

  • Article
  • Open Access
16 Citations
4,356 Views
14 Pages

29 July 2022

The purpose of this study was to understand the demographic, student, financial, and academic differences between marginally food secure college students and students with high, low, or very low food security (FS). Unlike highly food secure students,...

  • Article
  • Open Access
49 Citations
7,813 Views
13 Pages

Marginal Accuracy and Internal Fit of 3-D Printing Laser-Sintered Co-Cr Alloy Copings

  • Myung-Joo Kim,
  • Yun-Jung Choi,
  • Seong-Kyun Kim,
  • Seong-Joo Heo and
  • Jai-Young Koak

23 January 2017

Laser sintered technology has been introduced for clinical use and can be utilized more widely, accompanied by the digitalization of dentistry and the development of direct oral scanning devices. This study was performed with the aim of comparing the...

  • Review
  • Open Access
17 Citations
4,879 Views
25 Pages

Intraoperative Imaging Techniques to Improve Surgical Resection Margins of Oropharyngeal Squamous Cell Cancer: A Comprehensive Review of Current Literature

  • Bertram J. de Kleijn,
  • Gijs T. N. Heldens,
  • Jasmijn M. Herruer,
  • Cornelis F. M. Sier,
  • Cesare Piazza,
  • Remco de Bree,
  • Orlando Guntinas-Lichius,
  • Luiz P. Kowalski,
  • Vincent Vander Poorten and
  • Robert P. Takes
  • + 7 authors

31 January 2023

Inadequate resection margins in head and neck squamous cell carcinoma surgery necessitate adjuvant therapies such as re-resection and radiotherapy with or without chemotherapy and imply increasing morbidity and worse prognosis. On the other hand, tak...

  • Article
  • Open Access
151 Views
18 Pages

Fit of Three-Unit Posterior Fixed Dental Prostheses Made from Tetragonal Zirconia Polycrystal by 3D Printing and Milling

  • Jana Kostunov,
  • Jannis Crocoll,
  • Sebastian Hetzler,
  • Peter Rammelsberg,
  • Jonas Zeiß,
  • Andreas Zenthöfer and
  • Stefan Rues
Materials2026, 19(3), 597;https://doi.org/10.3390/ma19030597 
(registering DOI)

3 February 2026

(1) Objective: To compare the marginal and internal fit of 3D-printed and milled three-unit fixed dental prostheses (FDPs) made from tetragonal zirconia polycrystal (3Y-TZP). (2) Methods: Three-unit FDPs were designed for a typodont maxillary model w...

  • Article
  • Open Access
5 Citations
2,603 Views
21 Pages

Numerical Study Regarding the Seismic Response of a Moment-Resisting (MR) Reinforced Concrete (RC) Frame Structure with Reduced Cross-Sections of the RC Slabs

  • Ion Sococol,
  • Petru Mihai,
  • Tudor-Cristian Petrescu,
  • Florin Nedeff,
  • Valentin Nedeff,
  • Maricel Agop and
  • Bogdan-Ionel Luca

23 September 2022

In the first part of the current study, the effectiveness of the transversal cross-section reduction method for RC beams in marginal areas (by means of mechanical drilling) was validated. The said method “encourages” the formation of plas...

  • Article
  • Open Access
4 Citations
1,223 Views
20 Pages

We built a regional geological section founded upon the assessment of a seismic line in the Volturno basin, which is situated on the northern Campania continental shelf of the Tyrrhenian margin of Southern Italy. This section has been integrated with...

  • Article
  • Open Access
16 Citations
3,778 Views
13 Pages

The Influence of Thermomechanical Compaction on the Marginal Adaptation of 4 Different Hydraulic Sealers: A Comparative Ex Vivo Study

  • Alessio Zanza,
  • Rodolfo Reda,
  • Elisa Vannettelli,
  • Orlando Donfrancesco,
  • Michela Relucenti,
  • Shilpa Bhandi,
  • Shankargouda Patil,
  • Deepak Mehta,
  • Jogikalmat Krithikadatta and
  • Luca Testarelli

Since there are no data in the literature regarding the comparison of the marginal adaptation of hydraulic sealers when used with a single-cone technique or through thermomechanical compaction, this study aimed to evaluate the behavior of four differ...

  • Article
  • Open Access
12 Citations
908 Views
9 Pages

1 February 2016

Background: Obtaining accurate histopathologic detail for breast lumpectomy specimens is challenging because of sampling and loss of three-dimensional conformational features with conventional processing. The whole-mount (WM) technique is a novel met...

  • Article
  • Open Access
1,570 Views
13 Pages

Fresh Hemorrhages in Intestinal Resection Margins Are Associated with Unfavorable Clinical Outcomes in Preterm Infants with Necrotizing Enterocolitis with Surgical Intervention

  • Ole Schickedanz,
  • Florian Friedmacher,
  • Steffen Gretser,
  • Yannick Braun,
  • Peter Johanes Wild,
  • Udo Rolle and
  • Elise Gradhand

20 November 2024

Background: Necrotizing enterocolitis (NEC) is a common disease in premature infants. If conservative treatment does not respond, surgical removal of the necrotic section of bowel is common practice. This study investigates whether there is a correla...

  • Article
  • Open Access
3,837 Views
41 Pages

The Cantwell Formation of the central Alaska Range provides a robust archive of high-latitude, Late Cretaceous depositional systems and paleo-floral/faunal assemblages. Our stratigraphic analysis defines two mappable members. The lower member (1500&n...

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