1,425 Results Found

Our study proposes a pharmacological strategy to target cancerous mitochondria via redox-cycling “mitocans” such as quinone/ascorbate (Q/A) redox-pairs, which makes cancer cells fragile and sensitive without adverse effects on normal cell...

This work presents an in vivo stem-mounted sensor for Nicotiana tabacum plants and an in situ cell suspension sensor for Solanum lycopersicum cells. Stem-mounted sensors are mechanically stable and less sensitive to plant and air movements than the p...

Optical bioassays are challenged by the growing requirements of sensitivity and simplicity. Recent developments in the combination of redox cycling with different optical methods for signal amplification have proven to have tremendous potential for i...

Solid oxide fuel cells are able to convert fuels, including hydrocarbons, to electricity with an unbeatable efficiency even for small systems. One of the main limitations for long-term utilization is the reduction-oxidation cycling (RedOx cycles) of...

Cerium oxide nanoparticles (CeNPs) exhibit antioxidant properties both in vitro and in vivo. This is due to the self-regeneration of their surface, which is based on redox-cycling between 3+ and 4+ states for cerium, in response to their immediate en...

Biogeochemical redox cycling of iron (Fe) essentially governs various geochemical processes in nature. However, the mechanistic underpinnings of Fe-redox cycling in deep-sea sediments remain poorly understood, due to the limited access to the deep-se...

This paper describes a paper-based biochemical sensor that realizes redox cycling with close interelectrode distance. Two electrodes, the generator and collector electrodes, can detect steady-state oxidation and reduction currents when suitable poten...

We report the microfabrication and characterization of concentric gold nanoring electrodes (Au NREs), which were fabricated by patterning two gold nanoelectrodes on the same silicon (Si) micropillar tip. Au NREs of 165 ± 10 nm in width were mi...

With the aim of increasing the structural diversity on the early antimalarial drug plasmodione, an efficient and versatile procedure to prepare a series of biaryl- and N-arylalkylamines as plasmodione analogues is described. Using the naturally occur...

The enzymatic reactivity of a series of benzo[1,2-c]1,2,5-oxadiazole N-oxides (benzofuroxans; BFXs) towards mammalian single-electron transferring NADPH:cytochrome P-450 reductase (P-450R) and two-electron (hydride) transferring NAD(P)H:quinone oxido...

Enzyme-linked electrochemical immunosensors have attracted considerable attention for the sensitive and selective detection of various targets in clinical diagnosis, food quality control, and environmental analysis. In order to improve the performanc...

The Limulus amebocyte lysate (LAL) reaction-based assay, the most commonly used endotoxin detection method, requires a skilled technician. In this study, to develop an easy-to-use and highly sensitive endotoxin sensor, we created an electrochemical e...

Chemical synthesis of the conducting polymer polypyrrole induced by [Fe(CN)₆]³⁻ is reported. Reaction kinetics were characterized spectrophotometrically. Reaction rate was evaluated at several different pH levels in the presence of [Fe(CN)₆]^3&m...

Previous findings have demonstrated that β-sitosterol (BSS), an active component of Cistanches Herba, protected against oxidant injury in H9c2 cardiomyocytes and in rat hearts by enhancing mitochondrial glutathione redox cycling, possibly through the...

The chemical looping reforming of methane using an SrFeO₃ oxygen carrier to produce synthesis gas from solar energy was experimentally investigated and validated. High-temperature solar heat was used to provide the reaction enthalpy, and therefore th...

Herba Cynomorii (Cynomorium songaricum Rupr., Cynomoriaceae) is one of the most commonly used ‘Yang-invigorating’ tonic herbs in Traditional Chinese Medicine (TCM). An earlier study in our laboratory has demonstrated that HCY2, an ursolic acid-enrich...

The interest in and need for carbon-free fuels that do not rely on fossil fuels are constantly growing from both environmental and energetic perspectives. Green hydrogen production is at the core of the transition away from conventional fuels. Along...

The main challenges and obstacles to the development of hydrogen/carbon monoxide production from the splitting of water/carbon dioxide through two-step solar thermochemical cycles are strongly related to material concerns. Ineed, ceria is the main be...

In the past decade, selenocyclization has been extensively exploited for the preparation of a wide range of selenylated heterocycles with versatile activities. Previously, selenium electrophile-based and FeCl₃-promoted methods were employed for the s...

Imbalanced osteogenic cell-mediated bone gain and osteoclastic remodeling accelerates the development of osteoporosis, which is the leading risk factor of disability in the elderly. Harmonizing the metabolic actions of bone-making cells and bone reso...

The solar thermochemical two-step splitting of H₂O and CO₂ based on metal oxide compounds is a promising path for clean and efficient generation of hydrogen and renewable synthetic fuels. The two-step process is based on the endothermic solar thermal...

The significant accumulation of Pb from anthropogenic activities threatens environmental ecosystems. In the environment, iron oxides are one of the main carriers of Pb. Thus, the redox cycling of iron oxides, which is due to biotic and abiotic pathwa...

The coal mining subsidence area constitutes a distinct ecotone in the transition from agricultural soil to sediment, yet the microbially mediated nitrogen cycle within it remains inadequately understood. This investigation comprehensively analyzed ph...

Nitrofurantoin is utilized in various industries, including dairy, livestock, poultry, and aquaculture, as a growth promoter and antibacterial agent. Because prolonged use can cause mutagenesis and other side effects, many countries have prohibited i...

Previously, catalytic cerium oxide nanoparticles (CNPs, nanoceria, CeO2-x NPs) have been widely utilized for chemical mechanical planarization in the semiconductor industry and for reducing harmful emissions and improving fuel combustion efficiency i...

Parkinson’s disease, like other neurodegenerative diseases, exhibits two common features: Proteinopathy and oxidative stress, leading to protein aggregation and mitochondrial damage respectively. Because both protein aggregates and dysfunctiona...

Redox cycling is a phenomenon that occurs for redox species due to close interelectrode distance. [...]

Ferredoxin:NADP⁺ oxidoreductase from Plasmodium falciparum (PfFNR) catalyzes the NADPH-dependent reduction of ferredoxin (PfFd), which provides redox equivalents for the biosynthesis of isoprenoids and fatty acids in the apicoplast. Like other flavin...

A highly sensitive self-powered photoelectrochemical (spPEC) sensing platform was constructed for Hg²⁺ determination based on the g-C₃N₄-CdS-CuO co-sensitized photoelectrode and a visible light-induced redox cycle for signal amplification. Through su...

Background: Cancer cell sensitivity to drugs may be associated with disturbed antioxidant enzymes expression. We investigated mechanisms of resistance by using oxidative stress-resistant MCF-7 breast cancer cells (Resox cells). Since nicotinamide ade...

Layered double hydroxide (LDH) materials have shown charming photo-Fenton capability for the treatment of refractory organic wastewater. In this study, CuFe-LDH hybridized with N-doped carbon quantum dots (N-CQDs) was investigated to further enhance...

Catechins, the dietary phytochemicals present in green tea and other beverages, are considered to be potent inducers of apoptosis and cytotoxicity to cancer cells. While it is believed that the antioxidant properties of catechins and related dietary...

Air pollution remains a serious problem in Krakow, Poland. According to the European Environmental Agency, annual mean levels of both PM2.5 and PM10 recorded in Krakow are much higher than EU limit values. Thus, the influence of particulate matter (P...

Peroxiredoxin 6 (Prdx6) is the only member of 1-Cys subfamily of peroxiredoxins in human cells. It is the only Prdx acting on phospholipid hydroperoxides possessing two additional sites with phospholipase A2 (PLA2) and lysophosphatidylcholine-acyl tr...

Thermochemical processes are considered promising pathways to utilize solar energy for fuel production. Several physico-chemical, kinetic and thermodynamic properties of candidate oxides have been studied, yet their morphological stability during red...

The thermochemical water-splitting method is a promising technology for efficiently converting renewable thermal energy sources into green hydrogen. This technique is primarily based on recirculating an active material, capable of experiencing multip...

Hydrogen storage based on the repeated reduction and oxidation (redox) reactions of iron oxide/iron composites represents a promising technology. This work is dedicated to studying the influence of the amount of water added during the pelletizing pro...

Interactions between soils and climate impact wider environmental sustainability. Soil heterogeneity intricately regulates these interactions over short spatiotemporal scales and therefore needs to be more finely examined. This paper examines how red...

Zirconium-Yttrium-co-doped ceria (Ce_0.85Zr_0.13Y_0.02O_1.99) compacts consisting of fibers with diameters in the range of 8–10 µm have been successfully prepared by direct infiltration of commercial YSZ fibers with a cerium oxide matrix and subsequent s...

Polysulfide-ferricyanide redox flow batteries (PFRFBs) are gaining significant attention in long-duration energy storage for their abundant availability and environmental benignity. However, the sluggish kinetics of the polysulfide redox reactions ha...

We report the fabrication of nanoscale MoS₂ (nMoS₂) via laser ablation in liquid and its application in electrochemical sensing. The laser ablation process fragments microscale MoS₂ sheets into ~5 nm dots with stable aqueous dispersibility. Electroch...

This study focuses on the generation of solar thermochemical fuel (hydrogen, syngas) from CO₂ and H₂O molecules via two-step thermochemical cycles involving intermediate oxygen-carrier redox materials. Different classes of redox-active compounds base...

Glioblastoma is one of the most aggressive brain tumors, characterized by a pronounced redox imbalance, expressed in a high oxidative capacity of cancer cells due to their elevated glycolytic and mitochondrial oxidative metabolism. The assessment and...

The effects of substitution at the A- and B sites on the redox performance of a series of lanthanum–strontium–manganese (LSM)-based perovskite oxides (Z = Ni, Co, and Mg) were studied for application in a two-step thermochemical CO₂ split...

Soils are the dominant source of atmospheric nitrous oxide (N₂O), especially agricultural soils that experience both waterlogging and intensive nitrogen fertilization. However, soil heterogeneity and the irregular occurrence of hydrological events ha...

Naphthoquinones may cause oxidative stress in exposed cells and, therefore, affect redox signaling. Here, contributions of redox cycling and alkylating properties of quinones (both natural and synthetic, such as plumbagin, juglone, lawsone, menadione...

Solar thermochemical processes have the potential to efficiently convert high-temperature solar heat into storable and transportable chemical fuels such as hydrogen. In such processes, the thermal energy required for the endothermic reaction is suppl...

Background: Dark anaerobiosis promotes the acidification of the thylakoid lumen and a reduction in the plastoquinone (PQ) pool. The relationship between the reduction in the PQ pool in the dark and the induction of the xanthophyll cycle under high li...

Iron redox cycling in paddy soils drives the release and mineralisation of dissolved organic carbon (DOC), influencing the emission of CO₂ and CH₄. Light irradiation exerts an inhibitory effect on the mineralisation of soil organic carbon, but the re...

The global carbon cycle model is presented as a natural self-regulating machine that provides renewable biomass synthesis during evolution. The machine consists of two parts, geological and biosphere. Between the parts, there is an interaction. The g...