You are currently viewing a new version of our website. To view the old version click .

10,298 Results Found

  • Review
  • Open Access
33 Citations
6,400 Views
21 Pages

2 May 2020

Polyphenols are plant secondary metabolites with diverse biological and potential therapeutic activities such as antioxidant, anti-inflammatory and anticancer, among others. However, their extraction from the native plants is not enough to satisfy th...

  • Article
  • Open Access
2 Citations
2,730 Views
11 Pages

19 February 2021

New methods for the use of waste products as input for other technologies are a constant subject of research efforts. One such product is waste engine oil. Due to the constantly increasing number of motor vehicles in the world, the recycling or appli...

  • Proceeding Paper
  • Open Access
1 Citations
2,941 Views
7 Pages

Implementation of Design for Sustainability in Product Engineering

  • Yeturu Jaganmohan Reddy,
  • Gogulamudi Pradeep Reddy and
  • Yellapragada Venkata Pavan Kumar

22 November 2023

Product engineering involves the design and development of new products or the improvement of existing products to efficiently meet market needs and ensure high quality. Design for Excellence (DfX) concepts, such as Design for Manufacturing, Design f...

  • Proceeding Paper
  • Open Access
1 Citations
1,267 Views
9 Pages

23 January 2024

This study synthesizes a model of the main engineering and production chains in the Smart factory of Industry 4.0. This study has three main stages: an overview of the main definitions of the concepts “engineering and production chain” an...

  • Review
  • Open Access
75 Citations
8,972 Views
26 Pages

Flavonoid Production: Current Trends in Plant Metabolic Engineering and De Novo Microbial Production

  • Hasnat Tariq,
  • Saaim Asif,
  • Anisa Andleeb,
  • Christophe Hano and
  • Bilal Haider Abbasi

13 January 2023

Flavonoids are secondary metabolites that represent a heterogeneous family of plant polyphenolic compounds. Recent research has determined that the health benefits of fruits and vegetables, as well as the therapeutic potential of medicinal plants, ar...

  • Review
  • Open Access
28 Citations
6,815 Views
28 Pages

20 December 2020

Electromyography (EMG) signals are biomedical signals that measure electrical currents generated during muscle contraction. These signals are strongly influenced by physiological and anatomical characteristics of the muscles and represent the neuromu...

  • Review
  • Open Access
41 Citations
9,137 Views
16 Pages

18 January 2023

Even though sunlight energy far outweighs the energy required by human activities, its utilization is a key goal in the field of renewable energies. Microalgae have emerged as a promising new and sustainable feedstock for meeting rising food and feed...

  • Review
  • Open Access
6 Citations
5,715 Views
37 Pages

Genetic Engineering Approaches for the Microbial Production of Vanillin

  • Luísa D. F. Santos,
  • Sylvie Lautru and
  • Jean-Luc Pernodet

6 November 2024

Vanilla flavour is widely used in various industries and is the most broadly used flavouring agent in the food industry. The demand for this flavour is, therefore, extremely high, yet vanilla bean extracts can only meet about 1% of the overall demand...

  • Article
  • Open Access
10 Citations
6,411 Views
15 Pages

3 September 2022

Managing change in organizations is a laborious task that consumes value added time in various segments of the product lifecycle including design and development, production, delivery, and product disposition. Product lifecycle management plays an im...

  • Article
  • Open Access
2 Citations
2,768 Views
14 Pages

17 July 2020

Engineering education has a key role to play in equipping engineers with the design skills that they need to contribute to national competitiveness. Product design has been described as “the convergence point for engineering and design thinking...

  • Review
  • Open Access
40 Citations
17,978 Views
17 Pages

Production of Vitamin K by Wild-Type and Engineered Microorganisms

  • Min-Ji Kang,
  • Kwang-Rim Baek,
  • Ye-Rim Lee,
  • Geun-Hyung Kim and
  • Seung-Oh Seo

Vitamin K is a fat-soluble vitamin that mainly exists as phylloquinone or menaquinone in nature. Vitamin K plays an important role in blood clotting and bone health in humans. For use as a nutraceutical, vitamin K is produced by natural extraction, c...

  • Review
  • Open Access
51 Citations
9,064 Views
16 Pages

Microbial natural product drug discovery and development has entered a new era, driven by microbial genomics and synthetic biology. Genome sequencing has revealed the vast potential to produce valuable secondary metabolites in bacteria and fungi. How...

  • Article
  • Open Access
16 Citations
9,984 Views
18 Pages

Agile methods and software product line engineering (SPLE) are widely recognized as practical approaches for delivering high-quality software, adapting to evolving stakeholder needs, and tackling complex problems. This study proposes a hybrid agile s...

  • Article
  • Open Access
22 Citations
3,701 Views
21 Pages

A Methodology for the Design and Engineering of Smart Product Service Systems: An Application in the Manufacturing Sector

  • Veronica Arioli,
  • Giovanni Ruggeri,
  • Roberto Sala,
  • Fabiana Pirola and
  • Giuditta Pezzotta

21 December 2022

The combination of servitization and digitalization is increasingly changing the economy and society at the global level towards sustainability goals. Companies are shifting their business models, typically oriented to selling products, towards provi...

  • Article
  • Open Access
1,230 Views
15 Pages

Production of Lactate by Metabolically Engineered Scheffersomyces stipitis

  • Angela Matanović,
  • Nenad Marđetko,
  • Ana Slišković,
  • Blanka Didak,
  • Karla Hanousek Čiča,
  • Bojan Žunar,
  • Anamarija Štafa,
  • Božidar Šantek,
  • Marina Svetec Miklenić and
  • Ivan-Krešimir Svetec

27 May 2025

Lactate is a valuable compound used in food, chemical, and pharmaceutical industries. High-value, optically pure L- or D-lactate can be synthesized microbially via specific dehydrogenases. The non-conventional yeast Scheffersomyces stipitis, which is...

  • Review
  • Open Access
33 Citations
23,215 Views
17 Pages

Metabolic Engineering and Fermentation Process Strategies for L-Tryptophan Production by Escherichia coli

  • Lina Liu,
  • Muhammad Bilal,
  • Hongzhen Luo,
  • Yuping Zhao and
  • Hafiz M. N. Iqbal

12 April 2019

L-tryptophan is an essential aromatic amino acid that has been widely used in medicine, food, and animal feed. Microbial biosynthesis of L-tryptophan through metabolic engineering approaches represents a sustainable, cost-effective, and environmental...

  • Article
  • Open Access
4 Citations
1,978 Views
24 Pages

18 February 2025

The field of complex product design evaluation can attract high ambiguity due to difficulties in establishing indicators and the subjectivity of expert evaluation scoring. Indeed, traditional Kansei Engineering (KE) relies on user requirements and fe...

  • Article
  • Open Access
59 Citations
9,541 Views
17 Pages

26 November 2018

Creative product design is becoming critical to the success of many enterprises. However, the conventional product innovation process is hindered by two major challenges: the difficulty to capture users’ preferences and the lack of intuitive ap...

  • Review
  • Open Access
22 Citations
8,586 Views
19 Pages

8 July 2021

Metabolic engineering is a cutting-edge field that aims to produce simple, readily available, and inexpensive biomolecules by applying different genetic engineering and molecular biology techniques. Fatty acids (FAs) play an important role in determi...

  • Article
  • Open Access
1 Citations
1,205 Views
16 Pages

28 February 2025

Chaetoglobosin A (CheA), a typical structure of the cytochalasin family, exhibits outstanding efficacy against a variety of tumor cells and plant pathogens. However, its low yield and high production cost are major obstacles limiting its wide applica...

  • Article
  • Open Access
10 Citations
3,116 Views
15 Pages

24 April 2020

In Industry 4.0, people need to be able to handle the vast amount of information from machines. In this sense, for Industry 4.0, higher education institutions play a fundamental role. The methodology of this article sought to identify the knowledge r...

  • Article
  • Open Access
7 Citations
3,232 Views
15 Pages

Product Engineering Assessment of Subsea Intervention Equipment Using SWARA-MOORA-3NAG Method

  • Pedro Gall Fernandes,
  • Osvaldo Luiz Gonçalves Quelhas,
  • Carlos Francisco Simões Gomes,
  • Enderson Luiz Pereira Júnior,
  • Ricardo Luiz Fernandes Bella,
  • Claudio de Souza Rocha Junior,
  • Ruan Carlos Alves Pereira,
  • Marcio Pereira Basilio and
  • Marcos dos Santos

25 February 2023

Oilfields must increase their production due to the current price of oil barrels. The sale of these oilfields by big companies enabled new companies to enter the exploration and production segment of brownfields to increase oil and gas production thr...

  • Article
  • Open Access
1,305 Views
26 Pages

Machine Learning (ML) is increasingly applied across various domains, addressing tasks such as predictive analytics, anomaly detection, and decision-making. Many of these applications share similar underlying tasks, offering potential for systematic...

  • Article
  • Open Access
3 Citations
7,975 Views
20 Pages

This research examines differences in consumer responses to large language model AI chatbots versus search engines when reviewing and evaluating product information in the information search stage of the purchase decision process. Building on the mer...

  • Article
  • Open Access
32 Citations
6,693 Views
20 Pages

Fermentative N-Methylanthranilate Production by Engineered Corynebacterium glutamicum

  • Tatjana Walter,
  • Nour Al Medani,
  • Arthur Burgardt,
  • Katarina Cankar,
  • Lenny Ferrer,
  • Anastasia Kerbs,
  • Jin-Ho Lee,
  • Melanie Mindt,
  • Joe Max Risse and
  • Volker F. Wendisch

The N-functionalized amino acid N-methylanthranilate is an important precursor for bioactive compounds such as anticancer acridone alkaloids, the antinociceptive alkaloid O-isopropyl N-methylanthranilate, the flavor compound O-methyl-N-methylanthrani...

  • Communication
  • Open Access
8 Citations
10,468 Views
15 Pages

26 June 2018

Autonomous production needs to be reliable. Outputs from reliable production systems consistently conform to performance requirements. By contrast, outputs from unreliable production systems often do not conform to performance requirements. Unreliabl...

  • Review
  • Open Access
2 Citations
4,035 Views
19 Pages

9 November 2023

By progressively embracing the general principles of integrated, parametric, interdisciplinary design that considers the manufacturing elements of the imagined product, the modern aesthetic designer is called upon to broaden their knowledge and abili...

  • Review
  • Open Access
9 Citations
6,328 Views
28 Pages

27 March 2023

Yarrowia lipolytica has been a valuable biotechnological workhorse for the production of commercially important biochemicals for over 70 years. The knowledge gained so far on the native biosynthetic pathways, as well as the availability of numerous s...

  • Article
  • Open Access
330 Views
43 Pages

6 November 2025

Generative Artificial Intelligence (GAI) technologies are revolutionizing productivity and creativity across educational and engineering contexts. This study addresses a critical gap by examining the key factors influencing the successful integration...

  • Review
  • Open Access
18 Citations
7,141 Views
40 Pages

Microbiome Engineering for Sustainable Rice Production: Strategies for Biofertilization, Stress Tolerance, and Climate Resilience

  • Israt Jahan Misu,
  • Md. Omar Kayess,
  • Md. Nurealam Siddiqui,
  • Dipali Rani Gupta,
  • M. Nazrul Islam and
  • Tofazzal Islam

The plant microbiome, found in the rhizosphere, phyllosphere, and endosphere, is essential for nutrient acquisition, stress tolerance, and the overall health of plants. This review aims to update our knowledge of and critically discuss the diversity...

  • Article
  • Open Access
1,359 Views
21 Pages

20 May 2025

Durable plastics are a sustainability challenge for healthcare products. Orthopedic products are regulated with strict specifications for human tissue interactions. Healthcare engineers and managers select plastic to meet the full range of material p...

  • Article
  • Open Access
40 Citations
5,441 Views
25 Pages

11 August 2020

Product evaluation is very important for product improvement and development, and subjective product evaluation determines customer’s evaluation of products to some extent, so the purpose of this study is to establish a reasonable subjective pr...

  • Article
  • Open Access
16 Citations
4,609 Views
15 Pages

The modern world requires engineering specialists with excellent hard skills as well as soft skills that contribute to better communication, creativity, and self-realisation of a person. The authors discovered that modern educational standards are st...

  • Article
  • Open Access
21 Citations
3,309 Views
20 Pages

26 October 2020

Product–service systems (PSSs) have great potential for competitiveness and sustainability. Customers’ requirements cannot be directly used in the design of a PSS. Accurate identification of customer requirements, especially hidden requir...

  • Review
  • Open Access
30 Citations
6,285 Views
29 Pages

Lignin Valorization: Production of High Value-Added Compounds by Engineered Microorganisms

  • Elena Rosini,
  • Filippo Molinari,
  • Davide Miani and
  • Loredano Pollegioni

9 March 2023

Lignin is the second most abundant polymer in nature, which is also widely generated during biomass fractionation in lignocellulose biorefineries. At present, most of technical lignin is simply burnt for energy supply although it represents the riche...

  • Review
  • Open Access
7 Citations
1,834 Views
24 Pages

Defect Engineering of Nickel-Based Compounds for Energy-Saving H2 Production

  • Yi Zeng,
  • Xueqiang Qi,
  • Shun Lu,
  • Mohamed N. Khalil,
  • Xiuxiu Dong and
  • Haoqi Wang

2 August 2024

The urea oxidation reaction (UOR), requiring less energy to produce hydrogen, is considered as a potential alternative to the traditional oxygen evolution reaction. Consequently, developing highly efficient UOR catalysts to facilitate H2 production h...

  • Article
  • Open Access
14 Citations
4,779 Views
18 Pages

N-alkylated amino acids occur widely in nature and can also be found in bioactive secondary metabolites such as the glycopeptide antibiotic vancomycin and the immunosuppressant cyclosporine A. To meet the demand for N-alkylated amino acids, they are...

  • Review
  • Open Access
1 Citations
2,557 Views
9 Pages

15 January 2021

This review primarily describes nondestructive evaluation (NDE) work at Mississippi State University during the 2005–2020 time interval. Overall, NDE is becoming increasingly important as a means of maximizing and optimizing the value (economic...

  • Article
  • Open Access
1,137 Views
33 Pages

Reduction of Carbon Footprint in Mechanical Engineering Production Using a Universal Simulation Model

  • Juraj Kováč,
  • Peter Malega,
  • Erik Varjú,
  • Jozef Svetlík and
  • Rudolf Stetulič

11 May 2025

The paper presents the design and development of a universal simulation model named SustainSIM, intended for optimizing the carbon footprint in mechanical engineering production. The objective of this model is to enable enterprises to accurately quan...

  • Article
  • Open Access
40 Citations
9,580 Views
25 Pages

20 October 2017

Sustainability in the supply chain is becoming more and more important for industrial enterprises in different sectors. This research article focuses on construction supply chains (CSCs) in the Engineer-to-Order (ETO) industry, where every product is...

  • Article
  • Open Access
103 Citations
15,598 Views
21 Pages

Production of the Marine Carotenoid Astaxanthin by Metabolically Engineered Corynebacterium glutamicum

  • Nadja A. Henke,
  • Sabine A. E. Heider,
  • Petra Peters-Wendisch and
  • Volker F. Wendisch

30 June 2016

Astaxanthin, a red C40 carotenoid, is one of the most abundant marine carotenoids. It is currently used as a food and feed additive in a hundred-ton scale and is furthermore an attractive component for pharmaceutical and cosmetic applications with an...

  • Article
  • Open Access
76 Citations
8,597 Views
12 Pages

A Gram-Scale Limonene Production Process with Engineered Escherichia coli

  • Jascha Rolf,
  • Mattijs K. Julsing,
  • Katrin Rosenthal and
  • Stephan Lütz

18 April 2020

Monoterpenes, such as the cyclic terpene limonene, are valuable and important natural products widely used in food, cosmetics, household chemicals, and pharmaceutical applications. The biotechnological production of limonene with microorganisms may c...

  • Article
  • Open Access
5 Citations
3,268 Views
13 Pages

Erythromycins are a group of macrolide antibiotics produced by Saccharopolyspora erythraea. Erythromycin biosynthesis, which is a long pathway composed of a series of biochemical reactions, is precisely controlled by the type I polyketide synthases a...

  • Article
  • Open Access
1 Citations
654 Views
13 Pages

Synergistic Engineering of the Twin-Arginine Translocation (Tat) Pathway and Membrane Capacity Enhances Extracellular Production of Amylosucrase in Bacillus licheniformis

  • Caizhe Wang,
  • Dandan Niu,
  • Yongqing Zhou,
  • Hui Liu,
  • Nokuthula Peace Mchunu,
  • Meng Zhang,
  • Suren Singh and
  • Zhengxiang Wang

Amylosucrase (AS) is a highly versatile enzyme with significant potential for industrial applications, including functional food production and glycosylation of bioactive compounds. However, its large-scale production is hampered by low secretion eff...

  • Article
  • Open Access
7 Citations
4,948 Views
16 Pages

Uncovering the Indirect Impact of Work Ethic on Engineering Students’ Productivity through Positive and Negative Organizational Behaviors and Workaholism

  • Humayun Sattar,
  • Tasweer Hussain Syed,
  • Afshan Naseem,
  • Yasir Ahmad,
  • Muhammad Zeeshan Mirza and
  • Masood Raza

8 March 2021

The main objective of this study is to investigate the mediating effects of organizational citizenship behavior (OCB), destructive deviant behaviors (DDB), constructive deviant behaviors (CDB), and workaholism (WA) in the relationship between work et...

  • Article
  • Open Access
1 Citations
2,274 Views
13 Pages

16 December 2024

The implementation of smart technologies as well as artificial intelligence resulted in an increase in productivity and efficiency in production, optimization of costs, and automation of time-consuming processes. The situation is similar in the field...

  • Article
  • Open Access
30 Citations
7,093 Views
19 Pages

30 September 2021

Individual products and models on the market must be specifically differentiated from the rest to meet user demand. In terms of consumer purchasing behaviour, consumers increasingly base their decisions on subjective terms or the impression that the...

  • Article
  • Open Access
4 Citations
3,167 Views
15 Pages

Metabolic Engineering and Process Intensification for Muconic Acid Production Using Saccharomyces cerevisiae

  • Sinah Tönjes,
  • Evelien Uitterhaegen,
  • Ilse Palmans,
  • Birthe Ibach,
  • Karel De Winter,
  • Patrick Van Dijck,
  • Wim Soetaert and
  • Paul Vandecruys

24 September 2024

The efficient production of biobased organic acids is crucial to move to a more sustainable and eco-friendly economy, where muconic acid is gaining interest as a versatile platform chemical to produce industrial building blocks, including adipic acid...

  • Article
  • Open Access
2 Citations
1,965 Views
16 Pages

ScrumOntoSPL: Collaborative Method of Agile Product Line Engineering for Software Resource Reuse

  • Junhua Chen,
  • Rui Huang,
  • Yushuang Jiang,
  • Chenggen Pu,
  • Xueda Huang,
  • Xia Sun and
  • Yanfei Liu

Agile Product Line Engineering (APLE), a relatively new approach combining the two successful methods of Agile Software Development (ASD) and Software Product Lines (SPLs), makes product lines more responsive to ever-changing customer needs or market...

  • Article
  • Open Access
56 Citations
5,080 Views
19 Pages

11 February 2020

In order to facilitate the development of product image design, the research proposes the optimized product image design integrated decision system based on Kansei Engineering experiment. The system consists of two sub-models, namely product image de...

of 206