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12,307 Results Found

  • Article
  • Open Access
14 Citations
5,025 Views
17 Pages

Heating, ventilation, and air-conditioning systems (HVAC) have significant potential to support demand response programs within power grids. Model Predictive Control (MPC) is an effective technique for utilizing the flexibility of HVAC systems to ach...

  • Article
  • Open Access
23 Citations
3,896 Views
13 Pages

Pretreatment MRI Radiomics Based Response Prediction Model in Locally Advanced Cervical Cancer

  • Benedetta Gui,
  • Rosa Autorino,
  • Maura Miccò,
  • Alessia Nardangeli,
  • Adele Pesce,
  • Jacopo Lenkowicz,
  • Davide Cusumano,
  • Luca Russo,
  • Salvatore Persiani and
  • Giovanni Scambia
  • + 8 authors

The aim of this study was to create a radiomics model for Locally Advanced Cervical Cancer (LACC) patients to predict pathological complete response (pCR) after neoadjuvant chemoradiotherapy (NACRT) analysing T2-weighted 1.5 T magnetic resonance imag...

  • Article
  • Open Access
1,014 Views
19 Pages

27 May 2025

In this study, the effects of reduction temperature and time on the reduction rates of iron and vanadium oxides in low-grade vanadium–titanium magnetite (VTM) were investigated. Based on the results of physical experiments, both the response su...

  • Article
  • Open Access
7 Citations
2,498 Views
16 Pages

Development and Assessment of a Novel Core Biopsy-Based Prediction Model for Pathological Complete Response to Neoadjuvant Chemotherapy in Women with Breast Cancer

  • Ailin Lan,
  • Junru Chen,
  • Chao Li,
  • Yudi Jin,
  • Yinan Wu,
  • Yuran Dai,
  • Linshan Jiang,
  • Han Li,
  • Yang Peng and
  • Shengchun Liu

Purpose: Pathological complete response (pCR), the goal of NAC, is considered a surrogate for favorable outcomes in breast cancer (BC) patients administrated neoadjuvant chemotherapy (NAC). This study aimed to develop and assess a novel nomogram mode...

  • Article
  • Open Access
5 Citations
7,751 Views
29 Pages

7 October 2024

In today’s data-driven marketing landscape, predicting customer responses to marketing campaigns is essential for optimizing both engagement and Return On Investment (ROI). This study aims to develop a predictive model using a Decision Tree (DT...

  • Article
  • Open Access
1,971 Views
19 Pages

Decoding Anticancer Drug Response: Comparison of Data-Driven and Pathway-Guided Prediction Models

  • Efstathios Pateras,
  • Ioannis S. Vizirianakis,
  • Mingrui Zhang,
  • Georgios Aivaliotis,
  • Georgios Tzimagiorgis and
  • Andigoni Malousi

Background/Objective: Predicting pharmacological response in cancer remains a key challenge in precision oncology due to intertumoral heterogeneity and the complexity of drug–gene interactions. While machine learning models using multi-omics da...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,732 Views
38 Pages

16 February 2020

There is an increasing push to make automated systems capable of carrying out tasks which humans perform, such as driving, speech recognition, and anomaly detection. Automated systems, therefore, are increasingly required to respond to unexpected con...

  • Systematic Review
  • Open Access
6 Citations
2,763 Views
20 Pages

Validated Pretreatment Prediction Models for Response to Neoadjuvant Therapy in Patients with Rectal Cancer: A Systematic Review and Critical Appraisal

  • Max D. Tanaka,
  • Barbara M. Geubels,
  • Brechtje A. Grotenhuis,
  • Corrie A. M. Marijnen,
  • Femke P. Peters,
  • Stevie van der Mierden,
  • Monique Maas and
  • Alice M. Couwenberg

3 August 2023

Pretreatment response prediction is crucial to select those patients with rectal cancer who will benefit from organ preservation strategies following (intensified) neoadjuvant therapy and to avoid unnecessary toxicity in those who will not. The combi...

  • Article
  • Open Access
11 Citations
110 Views

The Use of Computational Models to Predict Response to HIV Therapy for Clinical Cases in Romania

  • Andrew D Revell,
  • LuminiŢA Ene,
  • Dan Duiculescu,
  • Dechao Wang,
  • Mike Youle,
  • Anton Pozniak,
  • Julio Montaner and
  • Brendan A Larder

1 March 2012

Introduction: A major challenge in Romania is the optimisation of antiretroviral therapy for the many HIV-infected adults with, on average, a decade of treatment experience. The RDI has developed computational models that predict virological response...

  • Article
  • Open Access
11 Citations
3,998 Views
13 Pages

Enhanced Co-Expression Extrapolation (COXEN) Gene Selection Method for Building Anti-Cancer Drug Response Prediction Models

  • Yitan Zhu,
  • Thomas Brettin,
  • Yvonne A. Evrard,
  • Fangfang Xia,
  • Alexander Partin,
  • Maulik Shukla,
  • Hyunseung Yoo,
  • James H. Doroshow and
  • Rick L. Stevens

11 September 2020

The co-expression extrapolation (COXEN) method has been successfully used in multiple studies to select genes for predicting the response of tumor cells to a specific drug treatment. Here, we enhance the COXEN method to select genes that are predicti...

  • Article
  • Open Access
9 Citations
3,465 Views
15 Pages

24 September 2024

The equilibrium swelling test was employed to determine the swelling response of Nitrile Butadiene Rubber (NBR) with various acrylonitrile (ACN) contents, and the three-dimensional solubility parameter (HSP) and modified Flory–Huggins interacti...

  • Article
  • Open Access
13 Citations
3,620 Views
19 Pages

15 March 2022

Recently, the integration of optimal battery dispatch and demand response has received much attention in improving DC microgrid operation under uncertainties in the grid-connect condition and distributed generations. However, the majority of prior st...

  • Article
  • Open Access
31 Citations
6,265 Views
20 Pages

27 December 2017

This paper focuses on flexible friction dampers (or “strips”) mounted on the underside of adjacent turbine blade platforms for sealing and damping purposes. A key parameter to ensure a robust and trustworthy design is the correct prediction of the ma...

  • Article
  • Open Access
1,679 Views
35 Pages

This paper proposes an innovative algorithm for forecasting the motion response of floating offshore wind turbines by employing force-to-motion transfer functions and state-space models. Traditional numerical integration techniques, such as the Newma...

  • Article
  • Open Access
1 Citations
2,372 Views
18 Pages

10 April 2022

The need to maintain the highest possible levels of bioactive components contained in raw materials requires the elaboration of tools supporting their processing operations, starting from the first stages of the food production chain. In this study,...

  • Feature Paper
  • Article
  • Open Access
93 Citations
10,476 Views
19 Pages

Model Predictive Control Home Energy Management and Optimization Strategy with Demand Response

  • Radu Godina,
  • Eduardo M. G. Rodrigues,
  • Edris Pouresmaeil,
  • João C. O. Matias and
  • João P. S. Catalão

9 March 2018

The growing demand for electricity is a challenge for the electricity sector as it not only involves the search for new sources of energy, but also the increase of generation capacity of the existing electrical infrastructure and the need to upgrade...

  • Article
  • Open Access
4 Citations
2,434 Views
14 Pages

29 June 2024

This paper proposes a novel approach that unifies a demand response (DR) with a master plan of the model predictive control method focusing on scheduling maintenance and replacement for suboptimal equipment in real-time solar power plants. By leverag...

  • Article
  • Open Access
3 Citations
1,794 Views
11 Pages

Logistic Regression Is Non-Inferior to the Response Surface Model in Patient Response Prediction of Video-Assisted Thoracoscopic Surgery

  • Hui-Yu Huang,
  • Shih-Pin Lin,
  • Hsin-Yi Wang,
  • Jing-Yang Liou,
  • Wen-Kuei Chang and
  • Chien-Kun Ting

10 January 2024

Response surface models (RSMs) are a new trend in modern anesthesia. RSMs have demonstrated significant applicability in the field of anesthesia. However, the comparative analysis between RSMs and logistic regression (LR) in different surgeries remai...

  • Article
  • Open Access
3 Citations
1,584 Views
18 Pages

14 October 2024

Jack-up offshore platforms are widely used in many fields, and it is of great importance to quickly and accurately predict the dynamic response of platform pile leg structures in real time. The current analytical techniques are founded upon numerical...

  • Article
  • Open Access
10 Citations
2,503 Views
14 Pages

Icing Time Prediction Model of Pavement Based on an Improved SVR Model with Response Surface Approach

  • Lingxiao Shangguan,
  • Yunfei Yin,
  • Qingtao Zhang,
  • Qun Liu,
  • Wei Xie and
  • Zejiao Dong

12 August 2022

Pavement icing imposes a great threat to driving safety and impacts the efficiency of the road transportation system in cold regions. This has attracted research predicting pavement icing time to solve the problems brought about by icing. Different m...

  • Article
  • Open Access
8 Citations
2,571 Views
11 Pages

29 September 2022

In this paper, the response surface methodology (RSM) is used to predict the flashover voltage of a cap and pin 1512L insulator used by SONELGAZ Algerian Power Company (SPE). The pollution and conductivity are studied using a two-level central compos...

  • Article
  • Open Access
18 Citations
6,062 Views
13 Pages

To make driving assistance system more humanized, this study focused on the prediction and assistance of drivers’ perception-response time on mountain highway curves. Field tests were conducted to collect real-time driving data and driver vision info...

  • Article
  • Open Access
6 Citations
3,662 Views
13 Pages

27 June 2024

By using omics, we can now examine all components of biological systems simultaneously. Deep learning-based drug prediction methods have shown promise by integrating cancer-related multi-omics data. However, the complex interaction between genes pose...

  • Article
  • Open Access
19 Citations
3,931 Views
11 Pages

11 September 2019

Metal-oxide (MOX) gas sensors are widely used for gas concentration estimation and gas identification due to their low cost, high sensitivity, and stability. However, MOX sensors have low selectivity to different gases, which leads to the problem of...

  • Article
  • Open Access
12 Citations
2,703 Views
20 Pages

Research on Hyperparameter Optimization of Concrete Slump Prediction Model Based on Response Surface Method

  • Yuan Chen,
  • Jiaye Wu,
  • Yingqian Zhang,
  • Lei Fu,
  • Yunrong Luo,
  • Yong Liu and
  • Lindan Li

5 July 2022

In this paper, eight variables of cement, blast furnace slag, fly ash, water, superplasticizer, coarse aggregate, fine aggregate and flow are used as network input and slump is used as network output to construct a back-propagation (BP) neural networ...

  • Article
  • Open Access
8 Citations
2,209 Views
38 Pages

3 October 2021

This work aims at underscoring the need for the accurate quantification of the sensitivities (i.e., functional derivatives) of the results (a.k.a. “responses”) produced by large-scale computational models with respect to the models’ parameters, which...

  • Article
  • Open Access
8 Citations
3,256 Views
29 Pages

25 February 2023

Currently, machine learning techniques are widely used in structural seismic response studies. The developed network models for various types of seismic response provide new ways to analyse seismic hazards. However, it is not easy to balance the appl...

  • Article
  • Open Access
5 Citations
3,104 Views
21 Pages

28 April 2023

Numerical models, such as multibody dynamics ones, are broadly used in various engineering applications, either as an integral part of the preliminary design of a product or simply to analyze its behavior. Aiming to increase the accuracy and potentia...

  • Article
  • Open Access
1,003 Views
20 Pages

Establishment of a Novel Fragmentation Prediction Model Incorporating Rock’s Response Time to Blasting

  • Meric Can Ozyurt,
  • Abdulkadir Karadogan,
  • Ulku Kalayci Sahinoglu,
  • Umit Ozer,
  • Hilal Erem Mutlu and
  • Taki Can Odabasi

28 August 2025

Rock’s response time to blasting (Tmin) refers to the critical time elapsed between the detonation of the explosive to the fragmentation and displacement of the rock, and it is a fundamental parameter that directly impacts blast-induced fragmen...

  • Article
  • Open Access
7 Citations
3,285 Views
28 Pages

23 September 2023

Deep neural networks (DNNs) have gained prominence in addressing regression problems, offering versatile architectural designs that cater to various applications. In the field of earthquake engineering, seismic response prediction is a critical area...

  • Article
  • Open Access
23 Citations
3,704 Views
11 Pages

External Validation of a Radiomics Model for the Prediction of Complete Response to Neoadjuvant Chemoradiotherapy in Rectal Cancer

  • Anaïs Bordron,
  • Emmanuel Rio,
  • Bogdan Badic,
  • Omar Miranda,
  • Olivier Pradier,
  • Mathieu Hatt,
  • Dimitris Visvikis,
  • François Lucia,
  • Ulrike Schick and
  • Vincent Bourbonne

21 February 2022

Objective: Our objective was to develop a radiomics model based on magnetic resonance imaging (MRI) and contrast-enhanced computed tomography (CE-CT) to predict pathological complete response (pCR) to neoadjuvant treatment in locally advanced rectal...

  • Article
  • Open Access
7 Citations
3,027 Views
14 Pages

26 August 2022

Surface wear, as a major failure mode of gear systems, is an unavoidable phenomenon during the whole life of gears. It also induces other gear damages, such as fatigue cracks, surface pitting and spalling. Ultimately, those defects may result in the...

  • Article
  • Open Access
11 Citations
3,920 Views
18 Pages

30 May 2021

Background: Cancer cell lines are frequently used in research as in-vitro tumor models. Genomic data and large-scale drug screening have accelerated the right drug selection for cancer patients. Accuracy in drug response prediction is crucial for suc...

  • Article
  • Open Access
4 Citations
1,965 Views
19 Pages

Assessment and Prediction of Coastal Ecological Resilience Based on the Pressure–State–Response (PSR) Model

  • Zhaoyi Wan,
  • Chengyi Zhao,
  • Jianting Zhu,
  • Xiaofei Ma,
  • Jiangzi Chen and
  • Junhao Wang

8 December 2024

Coastal zones are facing intensive ecological pressures and challenges, which could vary over a wide range of spatiotemporal scales. Our limited capability to understand and especially predict this variability can lead to the misinterpretation of coa...

  • Article
  • Open Access
180 Views
27 Pages

1 January 2026

To address the stochastic, nonlinear, and strongly coupled characteristics of multivariate long-term structural response in bridge health monitoring, this study proposes the Informer-SEnet prediction model. The model integrates a Squeeze-and-Excitati...

  • Article
  • Open Access
1 Citations
3,624 Views
17 Pages

Response Assessment in Long-Term Glioblastoma Survivors Using a Multiparametric MRI-Based Prediction Model

  • Laiz Laura de Godoy,
  • Archith Rajan,
  • Amir Banihashemi,
  • Thara Patel,
  • Arati Desai,
  • Stephen Bagley,
  • Steven Brem,
  • Sanjeev Chawla and
  • Suyash Mohan

31 January 2025

Purpose: Early treatment response assessments are crucial, and the results are known to better correlate with prognosis and survival outcomes. The present study was conducted to differentiate true progression (TP) from pseudoprogression (PsP) in long...

  • Article
  • Open Access
1 Citations
1,386 Views
16 Pages

Validation of Quantitative Ultrasound and Texture Derivative Analyses-Based Model for Upfront Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer

  • Adrian Wai Chan,
  • Lakshmanan Sannachi,
  • Daniel Moore-Palhares,
  • Archya Dasgupta,
  • Sonal Gandhi,
  • Rossanna Pezo,
  • Andrea Eisen,
  • Ellen Warner,
  • Frances C. Wright and
  • Gregory J. Czarnota
  • + 7 authors

This work was conducted in order to validate a pre-treatment quantitative ultrasound (QUS) and texture derivative analyses-based prediction model proposed in our previous study to identify responders and non-responders to neoadjuvant chemotherapy in...

  • Article
  • Open Access
7 Citations
1,524 Views
17 Pages

Prediction of Potential Distribution and Response of Changium smyrnioides to Climate Change Based on Optimized MaxEnt Model

  • Xingyu Zhu,
  • Xin Jiang,
  • Ying Chen,
  • Congcong Li,
  • Shi Ding,
  • Xuejiao Zhang,
  • Lulu Luo,
  • Yun Jia and
  • Gang Zhao

28 February 2025

Changium smyrnioides, an endangered herb known for its medicinal roots, contains essential amino acids that are vital for human health but cannot be synthesized by the body. However, wild populations of this species have been steadily declining due t...

  • Article
  • Open Access
1,392 Views
18 Pages

26 November 2024

This study presents a model of starved mixed Elastohydrodynamic Lubrication (EHL) in point and line contact to investigate the lubrication performance and material response. In formulating the governing equations for the lubrication, the dimensional...

  • Article
  • Open Access
5 Citations
3,854 Views
19 Pages

Improved Drug-Response Prediction Model of APC Mutant Colon Cancer Patient-Derived Organoids for Precision Medicine

  • Yong Jae Shin,
  • Eun Hae Jo,
  • Yunjeong Oh,
  • Da Som Kim,
  • Seungyoon Hyun,
  • Ahran Yu,
  • Hye Kyung Hong and
  • Yong Beom Cho

22 November 2023

Colorectal cancer is the third most common cancer in the world, with an annual incidence of 2 million cases. The success of first-line chemotherapy plays a crucial role in determining the disease outcome. Therefore, there is an increasing demand for...

  • Article
  • Open Access
5 Citations
2,905 Views
21 Pages

9 October 2019

The proposed study presents a novel probabilistic method for optimal allocation of spinning reserves taking into consideration load, wind and solar forecast errors, inter-zonal spinning reserve trading, and demand response provided by consumers as a...

  • Perspective
  • Open Access
1 Citations
1,554 Views
35 Pages

13 January 2023

This work presents a perspective on deterministic predictive modeling methodologies, which aim at extracting best-estimate values for model responses and parameters along with reduced predicted uncertainties for these best-estimate values. The two ol...

  • Article
  • Open Access
602 Views
27 Pages

10 November 2025

The integration of a high proportion of renewable energy has significantly reduced the grid inertia level and markedly increased the risk of transient frequency instability in power systems. Meanwhile, the large-scale integration of diverse heterogen...

  • Article
  • Open Access
528 Views
24 Pages

Surrogate-Model Prediction of Mechanical Response in Architected Ti6Al4V Cylindrical TPMS Metamaterials

  • Mansoureh Rezapourian,
  • Ali Cheloee Darabi,
  • Mohammadreza Khoshbin,
  • Siegfried Schmauder and
  • Irina Hussainova

15 December 2025

A Machine Learning (ML)-based surrogate modeling framework is presented for mapping structure–property relationships in architected Ti6Al4V cylindrical TPMS metamaterials subjected to quasi-static compression. A Python–nTop pipeline autom...

  • Article
  • Open Access
916 Views
14 Pages

10 November 2025

Background: Assessing the efficacy of combination therapies in hepatocellular carcinoma (HCC) requires both accurate tumor delineation and biologically validated prediction of therapeutic response. Conventional MRI-based criteria, which rely primaril...

  • Article
  • Open Access
4 Citations
2,351 Views
12 Pages

Automated Prediction of Neoadjuvant Chemoradiotherapy Response in Locally Advanced Cervical Cancer Using Hybrid Model-Based MRI Radiomics

  • Hua Yang,
  • Yinan Xu,
  • Mohan Dong,
  • Ying Zhang,
  • Jie Gong,
  • Dong Huang,
  • Junhua He,
  • Lichun Wei,
  • Shigao Huang and
  • Lina Zhao

Background: This study aimed to develop a model that automatically predicts the neoadjuvant chemoradiotherapy (nCRT) response for patients with locally advanced cervical cancer (LACC) based on T2-weighted MR images and clinical parameters. Methods: A...

  • Article
  • Open Access
4 Citations
2,038 Views
13 Pages

19 December 2022

To comprehensively obtain the effect of the machining process on the three-dimensional surface topography of machined potassium dihydrogen phosphate crystals, a dynamic response model of a machining system was built to calculate the dynamic displacem...

  • Article
  • Open Access
16 Citations
4,858 Views
16 Pages

Machine Learning Prediction of Treatment Response to Biological Disease-Modifying Antirheumatic Drugs in Rheumatoid Arthritis

  • Fatemeh Salehi,
  • Luis I. Lopera Gonzalez,
  • Sara Bayat,
  • Arnd Kleyer,
  • Dario Zanca,
  • Alexander Brost,
  • Georg Schett and
  • Bjoern M. Eskofier

2 July 2024

Background: Disease-modifying antirheumatic drugs (bDMARDs) have shown efficacy in treating Rheumatoid Arthritis (RA). Predicting treatment outcomes for RA is crucial as approximately 30% of patients do not respond to bDMARDs and only half achieve a...

  • Article
  • Open Access
4 Citations
2,430 Views
21 Pages

9 January 2023

We investigate the association of a sensitive characteristic or latent variable with observed binary random variables by the randomized response (RR) technique of Warner in his publication (Warner, S.L. J. Am. Stat. Assoc.1965, 60, 63–69) and a...

  • Review
  • Open Access
29 Citations
6,277 Views
27 Pages

23 November 2020

Head and neck squamous cell carcinoma (HNSCC) is characterized by a poor 5 year survival and varying response rates to both standard-of-care and new treatments. Despite advances in medicine and treatment methods, mortality rates have hardly decreased...

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