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77 Results Found

  • Article
  • Open Access
10 Citations
3,304 Views
14 Pages

INS/Vision Integrated Navigation System Based on a Navigation Cell Model of the Hippocampus

  • Xiaojie Liu,
  • Xiaoting Guo,
  • Donghua Zhao,
  • Chong Shen,
  • Chenguang Wang,
  • Jie Li,
  • Jun Tang and
  • Jun Liu

10 January 2019

Considering the error accumulation problem of a pure inertial navigation system (INS) under the condition of satellite signal outages, this paper proposes a brain-like navigation method based on a navigation cell model of the hippocampus to improve t...

  • Feature Paper
  • Article
  • Open Access
13 Citations
4,275 Views
19 Pages

Towards a Predictive Bio-Inspired Navigation Model

  • Simon Gay,
  • Kévin Le Run,
  • Edwige Pissaloux,
  • Katerine Romeo and
  • Christèle Lecomte

26 February 2021

This paper presents a novel bio-inspired predictive model of visual navigation inspired by mammalian navigation. This model takes inspiration from specific types of neurons observed in the brain, namely place cells, grid cells and head direction cell...

  • Feature Paper
  • Article
  • Open Access
4 Citations
2,327 Views
22 Pages

4 November 2022

This paper proposes a brain-inspired navigation model based on absolute heading for the autonomous navigation of unmanned platforms. The proposed model combined the sand ant’s strategy of acquiring absolute heading from the sky environment and...

  • Article
  • Open Access
4 Citations
3,645 Views
23 Pages

30 November 2021

Mammals rely on vision and self-motion information in nature to distinguish directions and navigate accurately and stably. Inspired by the mammalian brain neurons to represent the spatial environment, the brain-inspired positioning method based on mu...

  • Article
  • Open Access
2,262 Views
23 Pages

14 September 2023

Rats possess exceptional navigational abilities, allowing them to adaptively adjust their navigation paths based on the environmental structure. This remarkable ability is attributed to the interactions and regulatory mechanisms among various spatial...

  • Article
  • Open Access
1 Citations
3,097 Views
20 Pages

Deep Learning-Emerged Grid Cells-Based Bio-Inspired Navigation in Robotics

  • Arturs Simkuns,
  • Rodions Saltanovs,
  • Maksims Ivanovs and
  • Roberts Kadikis

4 March 2025

Grid cells in the brain’s entorhinal cortex are essential for spatial navigation and have inspired advancements in robotic navigation systems. This paper first provides an overview of recent research on grid cell-based navigation in robotics, f...

  • Article
  • Open Access
10 Citations
4,446 Views
13 Pages

14 November 2019

Autonomous navigation in unknown environments is still a challenge for robotics. Many efforts have been exerted to develop truly autonomous goal-oriented robot navigation models based on the neural mechanism of spatial cognition and mapping in animal...

  • Article
  • Open Access
3 Citations
3,435 Views
28 Pages

Neurophysiological studies have shown that the hippocampus, striatum, and prefrontal cortex play different roles in animal navigation, but it is still less clear how these structures work together. In this paper, we establish a navigation learning mo...

  • Article
  • Open Access
30 Citations
5,282 Views
23 Pages

1 April 2019

Extensive studies have shown that many animals’ capability of forming spatial representations for self-localization, path planning, and navigation relies on the functionalities of place and head-direction (HD) cells in the hippocampus. Although...

  • Article
  • Open Access
650 Views
20 Pages

24 September 2025

In this paper, we propose a quantitative evaluation method for navigation safety in coastal waters based on unstructured grids. Initially, a comprehensive analysis was conducted on various factors affecting navigation safety, including natural condit...

  • Communication
  • Open Access
1,666 Views
10 Pages

Self-location plays a crucial role in a framework of autonomous navigation, especially in a GNSS/radio-denied environment. At the current time, self-location for artificial agents still has to resort to the visual and laser technologies in the framew...

  • Communication
  • Open Access
18 Citations
5,470 Views
14 Pages

L5IN: Overview of an Indoor Navigation Pilot Project

  • Caroline Schuldt,
  • Hossein Shoushtari,
  • Nils Hellweg and
  • Harald Sternberg

9 February 2021

While outdoor navigation systems are already represented everywhere, the enclosed space is much less developed. The project Level 5 Indoor Navigation (L5IN) presents a new approach with mobile phone standard 5G as the orientation signal and without a...

  • Article
  • Open Access
26 Citations
4,289 Views
20 Pages

Relationships between Wind Effect, Hydrodynamics and Water Level in the World’s Largest Coastal Lagoonal System

  • Heline Oliveira,
  • Elisa Fernandes,
  • Osmar Möller and
  • Felipe García-Rodríguez

23 October 2019

The Patos-Mirim is the largest coastal limnological system of the world, located in southern Brazil and eastern Uruguay, which encompass over 500 km of coastline. The economical demand for the development of an international waterway brings the need...

  • Feature Paper
  • Review
  • Open Access
17 Citations
9,859 Views
15 Pages

The Role of Apoptotic Signaling in Axon Guidance

  • Riley Kellermeyer,
  • Leah M. Heydman,
  • Grant S. Mastick and
  • Thomas Kidd

18 October 2018

Navigating growth cones are exposed to multiple signals simultaneously and have to integrate competing cues into a coherent navigational response. Integration of guidance cues is traditionally thought to occur at the level of cytoskeletal dynamics. D...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,844 Views
20 Pages

12 June 2025

Magnetic soft continuum robots (MSCRs) have broad application advantages in vascular intervention; however, current MSCRs still face challenges in navigating the narrower and tortuous structure of the cerebral vasculature. To address this challenge,...

  • Article
  • Open Access
8 Citations
4,547 Views
29 Pages

8 January 2020

Occupancy grid is a popular environment model that is widely applied for autonomous navigation of mobile robots. This model encodes obstacle information into the grid cells as a reference of the space state. However, when navigating on roads, the pla...

  • Article
  • Open Access
1 Citations
1,080 Views
14 Pages

Cross-Path Planning of UAV Cluster Low-Altitude Flight Based on Inertial Navigation Combined with GPS Localization

  • Xiancheng Yang,
  • Ming Zhang,
  • Peihui Yan,
  • Qu Wang,
  • Dongpeng Xie and
  • Yuntian Brian Bai

To address the challenges of complex low-altitude flight environments for UAVs, where numerous obstacles often lead to GPS signal obstruction and multipath effects, this study proposes an integrated inertial navigation and GPS positioning approach fo...

  • Feature Paper
  • Article
  • Open Access
68 Citations
7,878 Views
32 Pages

Supporting Indoor Navigation Using Access Rights to Spaces Based on Combined Use of IndoorGML and LADM Models

  • Abdullah Alattas,
  • Sisi Zlatanova,
  • Peter Van Oosterom,
  • Efstathia Chatzinikolaou,
  • Christiaan Lemmen and
  • Ki-Joune Li

The aim of this research is to investigate the combined use of IndoorGML and the Land Administration Domain Model (LADM) to define the accessibility of the indoor spaces based on the ownership and/or the functional right for use. The users of the ind...

  • Article
  • Open Access
15 Citations
4,831 Views
30 Pages

13 April 2022

In a factory with different kinds of spatial atmosphere (warehouses, corridors, small or large workshops with varying sizes of obstacles and distribution patterns), the robot’s generated paths for navigation tasks mainly depend on the represent...

  • Article
  • Open Access
1 Citations
2,618 Views
13 Pages

Self-Regulated Symmetry Breaking Model for Stem Cell Differentiation

  • Madelynn McElroy,
  • Kaylie Green and
  • Nikolaos K. Voulgarakis

18 May 2023

In conventional disorder–order phase transitions, a system shifts from a highly symmetric state, where all states are equally accessible (disorder) to a less symmetric state with a limited number of available states (order). This transition may...

  • Review
  • Open Access
50 Citations
9,127 Views
25 Pages

Adult Hippocampal Neurogenesis in Different Taxonomic Groups: Possible Functional Similarities and Striking Controversies

  • Marcus Augusto-Oliveira,
  • Gabriela P. F. Arrifano,
  • João O. Malva and
  • Maria Elena Crespo-Lopez

5 February 2019

Adult neurogenesis occurs in many species, from fish to mammals, with an apparent reduction in the number of both neurogenic zones and new neurons inserted into established circuits with increasing brain complexity. Although the absolute number of ne...

  • Article
  • Open Access
971 Views
13 Pages

A Two-State Random Walk Model of Sperm Search on Confined Domains

  • Martin Bier,
  • Maciej Majka and
  • Cameron Schmidt

19 May 2025

Mammalian fertilization depends on sperm successfully navigating a spatially and chemically complex microenvironment in the female reproductive tract. This process is often conceptualized as a competitive race, but is better understood as a collectiv...

  • Review
  • Open Access
10 Citations
11,909 Views
18 Pages

The Yin-Yang of DNA Damage Response: Roles in Tumorigenesis and Cellular Senescence

  • Xiaoman Li,
  • Hongde Xu,
  • Chongan Xu,
  • Meina Lin,
  • Xiaoyu Song,
  • Fei Yi,
  • Yanling Feng,
  • Kathleen A. Coughlan,
  • William Chi-shing Cho and
  • Liu Cao

25 January 2013

Senescent cells are relatively stable, lacking proliferation capacity yet retaining metabolic activity. In contrast, cancer cells are rather invasive and devastating, with uncontrolled proliferative capacity and resistance to cell death signals. Alth...

  • Feature Paper
  • Article
  • Open Access
5 Citations
1,674 Views
50 Pages

AI-Enhanced Eco-Efficient UAV Design for Sustainable Urban Logistics: Integration of Embedded Intelligence and Renewable Energy Systems

  • Luigi Bibbò,
  • Filippo Laganà,
  • Giuliana Bilotta,
  • Giuseppe Maria Meduri,
  • Giovanni Angiulli and
  • Francesco Cotroneo

2 October 2025

The increasing use of UAVs has reshaped urban logistics, enabling sustainable alternatives to traditional deliveries. To address critical issues inherent in the system, the proposed study presents the design and evaluation of an innovative unmanned a...

  • Article
  • Open Access
388 Views
14 Pages

Rapid ART Initiation with BIC/FTC/TAF in People Who Inject Drugs in Greece: Results from a Pilot Single-Arm Study of an Integrated Care Model

  • Sotirios Roussos,
  • Konstantinos Protopapas,
  • Elpida Mastrogianni,
  • Charisis Totsikas,
  • Charalampos D. Moschopoulos,
  • Stylianos Bourmpoutelis,
  • Panagiota Resta,
  • Kassandra Procter,
  • Evangelos Kokolesis and
  • Mina Psichogiou
  • + 6 authors

People who inject drugs (PWIDs) remain underserved in HIV care. Evidence on rapid antiretroviral therapy (ART) for PWID is limited. We evaluated feasibility, effectiveness, safety, and patient-reported outcomes (PROs) for rapid initiation of bictegra...

  • Article
  • Open Access
5 Citations
2,805 Views
10 Pages

Droplets for Gene Editing Using CRISPR-Cas9 and Clonal Selection Improvement Using Hydrogels

  • Camilo Pérez-Sosa,
  • Maximiliano S. Pérez,
  • Alexander Paolo Vallejo-Janeta,
  • Shekhar Bhansali,
  • Santiago Miriuka and
  • Betiana Lerner

19 March 2024

Gene editing tools have triggered a revolutionary transformation in the realms of cellular and molecular physiology, serving as a fundamental cornerstone for the evolution of disease models and assays in cell culture reactions, marked by various enha...

  • Review
  • Open Access
1 Citations
3,520 Views
25 Pages

15 August 2025

This article reviews and synthesizes highlights of the history of neural models of rate-based and spiking neural networks. It explains that theoretical and experimental results about how all rate-based neural network models, whose cells obey the memb...

  • Article
  • Open Access
6 Citations
3,240 Views
19 Pages

18 July 2024

Recent advancements in simultaneous localization and mapping (SLAM) have significantly improved the handling of dynamic objects. Traditionally, SLAM systems mitigate the impact of dynamic objects by extracting, matching, and tracking features. Howeve...

  • Article
  • Open Access
1 Citations
1,856 Views
17 Pages

Predicting cellular responses to perturbations is an unsolved problem in biology. Traditional approaches assume that different cell types respond similarly to perturbations. However, this assumption does not take into account the context of genome in...

  • Article
  • Open Access
3 Citations
3,854 Views
33 Pages

1 September 2022

Since the hippocampus plays an important role in memory and spatial cognition, the study of spatial computation models inspired by the hippocampus has attracted much attention. This study relies mainly on reward signals for learning environments and...

  • Article
  • Open Access
1 Citations
3,224 Views
28 Pages

6 February 2025

This paper addresses the critical challenge of understanding and interpreting deep learning models in Global Navigation Satellite System (GNSS) applications, specifically focusing on multipath effect detection and analysis. As GNSS systems become inc...

  • Article
  • Open Access
2 Citations
2,649 Views
21 Pages

30 March 2023

Kalman filter is a well-established accuracy correction method in control, guidance, and navigation. With the popularity of mobile communication and ICT, Kalman Filter has been used in many new applications related to positioning based on spatiotempo...

  • Review
  • Open Access
5 Citations
4,632 Views
9 Pages

Computational Approaches to Explore Bacterial Toxin Entry into the Host Cell

  • Weria Pezeshkian,
  • Julian C. Shillcock and
  • John H. Ipsen

28 June 2021

Many bacteria secrete toxic protein complexes that modify and disrupt essential processes in the infected cell that can lead to cell death. To conduct their action, these toxins often need to cross the cell membrane and reach a specific substrate ins...

  • Review
  • Open Access
4 Citations
7,774 Views
24 Pages

Radiobiology and Reproduction—What Can We Learn from Mammalian Females?

  • Aurora Ruiz-Herrera,
  • Francisca Garcia and
  • Montserrat Garcia-Caldés

27 August 2012

Ionizing radiation damages DNA and induces mutations as well as chromosomal reorganizations. Although radiotherapy increases survival among cancer patients, this treatment does not come without secondary effects, among which the most problematic is g...

  • Article
  • Open Access
1 Citations
2,447 Views
19 Pages

15 March 2024

In previous studies of ship–ice interactions, most studies focused on ship–level ice interactions, overlooking potential rafted ice conditions in extreme ice conditions. The purpose of this study is to develop a numerical model for predic...

  • Article
  • Open Access
26 Citations
6,199 Views
17 Pages

Road Profile Estimation Using a 3D Sensor and Intelligent Vehicle

  • Tao Ni,
  • Wenhang Li,
  • Dingxuan Zhao and
  • Zhifei Kong

30 June 2020

Autonomous vehicles can achieve accurate localization and real-time road information perception using sensors such as global navigation satellite systems (GNSSs), light detection and ranging (LiDAR), and inertial measurement units (IMUs). With road i...

  • Article
  • Open Access
572 Views
14 Pages

27 October 2025

Neuromast cells are specialized mechanosensory receptor cells embedded within the lateral line system of aquatic vertebrates, enabling the detection of water movement and vibration that are essential for navigation, prey capture, and predator avoidan...

  • Article
  • Open Access
29 Citations
8,223 Views
15 Pages

A Novel General Imaging Formation Algorithm for GNSS-Based Bistatic SAR

  • Hong-Cheng Zeng,
  • Peng-Bo Wang,
  • Jie Chen,
  • Wei Liu,
  • LinLin Ge and
  • Wei Yang

26 February 2016

Global Navigation Satellite System (GNSS)-based bistatic Synthetic Aperture Radar (SAR) recently plays a more and more significant role in remote sensing applications for its low-cost and real-time global coverage capability. In this paper, a general...

  • Article
  • Open Access
1,940 Views
17 Pages

18 October 2022

Lq (0 < q ≤ 1) regularization has been confirmed effective when applied to sparse SAR imaging. However, the inaccuracies caused by motion errors in the observation model will lead to various degradations and defocus in the reconstructed image....

  • Review
  • Open Access
15 Citations
4,962 Views
20 Pages

Avian models have the potential to elucidate basic cellular and molecular mechanisms underlying the slow aging rates and exceptional longevity typical of this group of vertebrates. To date, most studies of avian aging have focused on relatively few o...

  • Article
  • Open Access
11 Citations
4,208 Views
17 Pages

Combined Traction Force–Atomic Force Microscopy Measurements of Neuronal Cells

  • Udathari Kumarasinghe,
  • Lucian N. Fox and
  • Cristian Staii

In the course of the development of the nervous system, neuronal cells extend (grow) axons, which navigate over distances of the order of many cell diameters to reach target dendrites from other neurons and establish neuronal circuits. Some of the ce...

  • Feature Paper
  • Review
  • Open Access
8 Citations
5,713 Views
19 Pages

Romanian Danube River Hydrocarbon Pollution in 2011–2021

  • Crina Radu,
  • Valentina-Mariana Manoiu,
  • Katarzyna Kubiak-Wójcicka,
  • Emilia Avram,
  • Andreea Beteringhe and
  • Alexandru-Ioan Craciun

7 October 2022

This review paper aims to analyze studies conducted over recent years (2011–2021) on hydrocarbon pollution in the Danube’s Romanian sector. This involves looking at three main issues: Space-related Romanian Danube hydrocarbon pollution; t...

  • Article
  • Open Access
1 Citations
2,762 Views
14 Pages

6 December 2023

Deciphering the dynamics of water transport across bronchial epithelial cell monolayers is pivotal for unraveling respiratory physiology and pathology. In this study, we employ an advanced microfluidic system to explore bidirectional water transport...

  • Article
  • Open Access
6 Citations
2,335 Views
16 Pages

Neuronal networks are complex systems of interconnected neurons responsible for transmitting and processing information throughout the nervous system. The building blocks of neuronal networks consist of individual neurons, specialized cells that rece...

  • Article
  • Open Access
7 Citations
5,200 Views
51 Pages

From Proteomic Mapping to Invasion-Metastasis-Cascade Systemic Biomarkering and Targeted Drugging of Mutant BRAF-Dependent Human Cutaneous Melanomagenesis

  • Aikaterini F. Giannopoulou,
  • Athanassios D. Velentzas,
  • Athanasios K. Anagnostopoulos,
  • Adamantia Agalou,
  • Nikos C. Papandreou,
  • Stamatia A. Katarachia,
  • Dimitra G. Koumoundourou,
  • Eumorphia G. Konstantakou,
  • Vasiliki I. Pantazopoulou and
  • Dimitrios J. Stravopodis
  • + 13 authors

22 April 2021

Melanoma is classified among the most notoriously aggressive human cancers. Despite the recent progress, due to its propensity for metastasis and resistance to therapy, novel biomarkers and oncogenic molecular drivers need to be promptly identified f...

  • Article
  • Open Access
7 Citations
3,226 Views
20 Pages

29 July 2022

Microorganisms often navigate a complex environment composed of a viscous fluid with suspended microstructures such as elastic polymers and filamentous networks. These microstructures can have similar length scales to the microorganisms, leading to c...

  • Article
  • Open Access
2 Citations
3,105 Views
18 Pages

Viability and Motility of Escherichia coli Under Elevated Martian Salt Stresses

  • Max Riekeles,
  • Berke Santos,
  • Sherif Al-Morssy Youssef and
  • Dirk Schulze-Makuch

21 November 2024

This study investigates the effects of three Martian-relevant salts—sodium chlorate, sodium perchlorate, and sodium chloride—on the viability and motility of Escherichia coli, a model organism for understanding microbial responses to envi...

  • Article
  • Open Access
16 Citations
4,277 Views
16 Pages

26 August 2019

Low performance of actively targeted nanomedicines required revision of the traditional drug targeting paradigm and stimulated the development of novel phage-programmed, self-navigating drug delivery vehicles. In the proposed smart vehicles, targetin...

  • Article
  • Open Access
1 Citations
5,082 Views
16 Pages

In the dynamic sphere of financial markets, hedge funds have emerged as a critical force, navigating through volatility with advanced risk management techniques yet grappling with the challenges posed by illiquid assets. This study aims to transcend...

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