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184 Results Found

  • Proceeding Paper
  • Open Access
4 Citations
2,160 Views
3 Pages

Nonparametric Inference for Mixture Cure Model When Cure Information Is Partially Available

  • Wende Clarence Safari,
  • Ignacio López-de-Ullibarri and
  • María Amalia Jácome

We introduce nonparametric estimators to estimate the conditional survival function, cure probability and latency function in the setting of a mixture cure model when the cure status is partially known. For the sake of illustration, we present an app...

(This article belongs to the Proceedings of The 4th XoveTIC Conference)
  • Article
  • Open Access
1 Citations
3,914 Views
16 Pages

8 February 2025

The mixture cure model has been widely used in medicine, public health, and bioinformatics. The traditional mixture cure model has limitations in model flexibility and handling complex structured data and big data. In recent years, some improved new...

(This article belongs to the Special Issue Advances in Statistics, Biostatistics and Medical Statistics)
  • Article
  • Open Access
2,290 Views
15 Pages

A Mixture Model for Survival Data with Both Latent and Non-Latent Cure Fractions

  • Eduardo Yoshio Nakano,
  • Frederico Machado Almeida and
  • Marcílio Ramos Pereira Cardial

13 September 2025

One of the most popular cure rate models in the literature is the Berkson and Gage mixture model. A characteristic of this model is that it considers the cure to be a latent event. However, there are situations in which the cure is well known, and th...

(This article belongs to the Section Biostatistics)
  • Article
  • Open Access
325 Views
23 Pages

19 July 2026

Accurately estimating the incubation period of emerging infectious diseases, defined as the time interval from infection to symptom onset, is essential for informing quarantine strategies and allocating public health resources. To address the challen...

(This article belongs to the Section B: Mathematics)
  • Article
  • Open Access
5 Citations
5,361 Views
14 Pages

28 December 2022

Mixture cure rate models have been developed to analyze failure time data where a proportion never fails. For such data, standard survival models are usually not appropriate because they do not account for the possibility of non-failure. In this cont...

(This article belongs to the Special Issue Information Theory for Data Science)
  • Article
  • Open Access
1 Citations
2,999 Views
13 Pages

Prognostic Factors Analysis of Metastatic Recurrence in Cervical Carcinoma Patients Treated with Definitive Radiotherapy: A Retrospective Study Using Mixture Cure Model

  • Xiaxian Ou,
  • Jing You,
  • Baosheng Liang,
  • Xiaofan Li and ,
  • Jiangjie Zhou,
  • Fengyu Wen,
  • Jingyuan Wang,
  • Zhengkun Dong and
  • Yibao Zhang
  • + 4 authors+ 0 author

25 May 2023

Objectives: This study aims to identify prognostic factors associated with metastatic recurrence-free survival of cervical carcinoma (CC) patients treated with radical radiotherapy and assess the cure probability of radical radiotherapy from metastat...

(This article belongs to the Special Issue Advances in Brachytherapy in the Treatment of Tumors)
  • Article
  • Open Access
10 Citations
5,560 Views
13 Pages

15 November 2018

This paper considers a non-mixture cure model for right-censored data. It utilizes the maximum likelihood method to estimate model parameters in the non-mixture cure model. The simulation study is based on Fréchet susceptible distribution to e...

  • Article
  • Open Access
1 Citations
1,381 Views
15 Pages

24 December 2025

When determining subgroups with heterogeneous treatment effects in cancer clinical trials, the threshold of a variable that defines subgroups is often pre-determined by physicians based on their experience, and the optimality of the threshold is not...

  • Article
  • Open Access
5 Citations
4,682 Views
21 Pages

2 October 2023

In classical survival analysis, it is assumed that all the individuals will experience the event of interest. However, if there is a proportion of subjects who will never experience the event, then a standard survival approach is not appropriate, and...

(This article belongs to the Special Issue Nonparametric Statistical Methods and Their Applications)
  • Extended Abstract
  • Open Access
2 Citations
2,296 Views
3 Pages

Nonparametric Inference in Mixture Cure Models

  • Ana López-Cheda,
  • Ricardo Cao,
  • Mª Amalia Jácome and
  • Ingrid Van Keilegom

17 September 2018

A completely nonparametric method for the estimation of mixture cure models is proposed. Nonparametric estimators for the cure probability (incidence) and for the survival function of the uncured population (latency) are introduced. In addition, a bo...

(This article belongs to the Proceedings of XoveTIC Congress 2018)
  • Article
  • Open Access
9 Citations
2,586 Views
16 Pages

Fatigue Cracking Evolution and Model of Cold Recycled Asphalt Mixtures during Different Curing Times

  • Yu Xia,
  • Juntao Lin,
  • Zongwu Chen,
  • Jun Cai and ,
  • Jinxiang Hong and
  • Xiaobin Zhu
  • + 1 author+ 0 author

24 June 2022

This paper aims to investigate the fatigue cracking evolution of cold recycled asphalt mixtures with asphalt emulsion (CRME) under different curing times. The fatigue cracking model of CRME based on damage mechanics and fracture mechanics was analyze...

(This article belongs to the Special Issue Long-Life and Circular Pavement Materials)
  • Review
  • Open Access
132 Citations
27,402 Views
29 Pages

The purpose of this paper is to review some of the key literature on response time as it has played a role in cognitive ability measurement, providing a historical perspective as well as covering current research. We discuss the speed-level distincti...

(This article belongs to the Special Issue Mental Speed and Response Times in Cognitive Tests)
  • Article
  • Open Access
9 Citations
4,097 Views
15 Pages

Cure Models with Exponentiated Weibull Exponential Distribution for the Analysis of Melanoma Patients

  • Mohamed Elamin Abdallah Mohamed Elamin Omer,
  • Mohd Rizam Abu Bakar,
  • Mohd Bakri Adam and
  • Mohd Shafie Mustafa

2 November 2020

In the survival data analysis, commonly, it is presumed that all study subjects will eventually have the event of concern. Nonetheless, it tends to be unequivocally expected that a fraction of these subjects will never expose to the event of interest...

(This article belongs to the Section D1: Probability and Statistics)
  • Article
  • Open Access
208 Views
38 Pages

21 October 2026

Reliable prediction of concrete strength development is important for mixture design and performance assessment, yet conventional experimental–statistical approaches often describe strength at discrete curing ages or require separate calibratio...

  • Article
  • Open Access
124 Views
13 Pages

Mechanical Performance and Strength Prediction of Non-Steam-Curing UHPC Considering Coupled Temperature-Constituent Effects

  • Changjin Tian,
  • Yefeng Du,
  • Ran An,
  • Youzhi Wang and ,
  • Xiaoning Zhang and
  • Lin Teng
  • + 1 author+ 0 author

27 October 2026

Non-steam-curing ultra-high-performance concrete (UHPC) is a promising material for in situ bridge deck rehabilitation; however, its strength development under variable curing temperatures remains insufficiently understood. This study investigated th...

(This article belongs to the Special Issue Reinforced Concrete: Mechanical Properties and Materials Design—Second Edition)
  • Review
  • Open Access
115 Citations
11,792 Views
14 Pages

5 January 2023

Anhydride-cured bisphenol-A epoxy resin is widely used in the support, insulation and sealing key components of electrical and electronic equipment due to their excellent comprehensive performance. However, overheating and breakdown faults of epoxy r...

(This article belongs to the Special Issue Epoxy Resin Synthesis, Performance and Application Research)
  • Article
  • Open Access
3 Citations
2,253 Views
24 Pages

Study on the Influence Factors of the Dynamic Property of the Polyurethane Mixture with Dense Gradation

  • Haisheng Zhao,
  • Shiping Cui,
  • Zhen Li,
  • Shaobin Wang and ,
  • Lin Wang,
  • Wensheng Zhang,
  • Chunhua Su,
  • Peiyu Zhang and
  • Shijie Ma
  • + 4 authors+ 0 author

20 August 2023

Similar to the asphalt mixture, the polyurethane (PU) mixture’s performance and characteristics are dependent on many variables. In this study, six variables, including aggregate gradation (limestone and basalt), aggregate type, PU type, PU con...

  • Article
  • Open Access
443 Views
25 Pages

16 September 2026

This study investigated the compressive-strength behavior of concrete containing RESIN8 recycled plastic, paying particular attention to food waste contamination. A total of 36 specimens representing conventional concrete, concrete containing unconta...

(This article belongs to the Special Issue Advancements in Eco-Friendly Concrete and Sustainable Construction Materials)
  • Article
  • Open Access
10 Citations
2,802 Views
14 Pages

Phase Equilibria, Diffusion and Structure in the Epoxypolycaprolactone System

  • Irina O. Plyusnina,
  • Nikita Yu. Budylin and
  • Alexey V. Shapagin

27 December 2022

Currently, there is no quantitative approach for the phase structure of cured thermoplastic systems modified with thermoplastic predicting. To solve this problem, we carried out the first stage of the study on a model polycaprolactone–epoxy oli...

(This article belongs to the Section Polymer Physics and Theory)
  • Article
  • Open Access
3 Citations
1,462 Views
21 Pages

AI-Driven Analysis of Tuff and Lime Effects on Basalt Fiber-Reinforced Clay Strength

  • Yasemin Aslan Topçuoğlu,
  • Zeynep Bala Duranay,
  • Zülfü Gürocak and
  • Hanifi Güldemir

11 July 2025

In this study, free compression tests were conducted to examine the changes in the strength of soil after adding 24 mm long basalt fiber (1%), lime (3%, 6%, 9% by dry weight), and tuff (10%, 20%, 30% by dry weight) before curing and after 28, 42, and...

  • Article
  • Open Access
37 Citations
6,446 Views
18 Pages

Compressive Strength Development of High-Volume Fly Ash Ultra-High-Performance Concrete under Heat Curing Condition with Time

  • Pham Sy Dong,
  • Nguyen Van Tuan,
  • Le Trung Thanh,
  • Nguyen Cong Thang and ,
  • Viet Hung Cu and
  • Ju-Hyun Mun
  • + 1 author+ 0 author

13 October 2020

This research investigated the effect of fly ash content on the compressive strength development of ultra-high-performance concrete (UHPC) at different curing conditions, i.e., the standard curing condition and the heat curing. A total of 20 mixtures...

(This article belongs to the Special Issue Sustainability and Performance of Advanced Construction Materials)
  • Article
  • Open Access
3 Citations
1,933 Views
15 Pages

A Study of Hydroxyl-Terminated Block Copolyether-Based Binder Curing Kinetics

  • Wu Yang,
  • Zhengmao Ding,
  • Cong Zhu,
  • Tianqi Li and ,
  • Wenhao Liu and
  • Yunjun Luo
  • + 1 author+ 0 author

7 August 2024

In order to determine the curing reaction model and corresponding parameters of hydroxyl-terminated block copolyether (HTPE) and provide a theoretical reference for its practical application, the non-isothermal differential scanning calorimetry (DSC)...

(This article belongs to the Special Issue Eco-Friendly Coatings and Adhesive Technology)
  • Article
  • Open Access
1 Citations
428 Views
24 Pages

Inaccurate prediction of shrinkage in self-compacting concrete (SCC) may result in underestimated cracking risk, increased permeability, serviceability deterioration, and reduced long-term durability of concrete structures. Although conventional empi...

(This article belongs to the Section Building Materials, and Repair & Renovation)
  • Article
  • Open Access
12 Citations
3,926 Views
18 Pages

Cross-Linking Reaction of Bio-Based Epoxy Systems: An Investigation into Cure Kinetics

  • Pietro Di Matteo,
  • Andrea Iadarola,
  • Raffaele Ciardiello,
  • Davide Salvatore Paolino and ,
  • Francesco Gazza,
  • Vito Guido Lambertini and
  • Valentina Brunella
  • + 2 authors+ 0 author

2 September 2024

The cure kinetics of various epoxy resin mixtures, comprising a bisphenol epoxy, two epoxy modifiers, and two hardening agents derived from cardanol technology, were investigated through differential scanning calorimetry (DSC). The development of the...

(This article belongs to the Special Issue Cross-Linked Polymers II)
  • Article
  • Open Access
944 Views
22 Pages

A Random Activation Framework for Cure Models with Waring-Distributed Latent Causes

  • Jonathan K. J. Vasquez,
  • Vera Tomazella,
  • Danilo Alvares,
  • Pedro Rafael D. Marinho and
  • Joaquín Martínez-Minaya

19 June 2026

This paper introduces a random activation framework for cure rate modeling that provides a novel latent mechanistic interpretation of the standard mixture cure model, utilizing a Waring-distributed number of latent causes. The proposed approach repre...

(This article belongs to the Section Biostatistics)
  • Article
  • Open Access
91 Views
20 Pages

31 October 2026

Abrupt temperature drops during cold waves pose a threat to early-age concrete in cold regions. This study combined electrical resistivity monitoring, compressive strength testing, and mesoscopic electrical modeling to investigate the performance of...

(This article belongs to the Special Issue Cement-Based/Non-Cement-Based Construction Materials: Multiscale Mechanics Under Diverse Loadings (Second Edition))
  • Article
  • Open Access
5 Citations
2,757 Views
10 Pages

20 June 2024

We outline a molecular simulation protocol for elucidating the formation of silicone oil from trimethlyl- and dimethlysilanediole precursor mixtures. While the fundamental condensation reactions are effectively described by quantum mechanical calcula...

(This article belongs to the Section Polymer Physics and Theory)
  • Article
  • Open Access
3 Citations
756 Views
21 Pages

17 April 2026

Early-age shrinkage is a critical factor governing the dimensional stability and cracking susceptibility of ultra-high-performance concrete (UHPC). However, accurate prediction of UHPC shrinkage remains challenging due to the strong nonlinear interac...

(This article belongs to the Special Issue Performance and Durability of Reinforced Concrete Structures)
  • Article
  • Open Access
255 Views
24 Pages

Development of a Cracking Resistance Index for Ballastless Track Slab Concrete: Evaluation and Mixture Optimization

  • Li Yang,
  • Hailin Lu,
  • Jing Hao,
  • Jicheng Zhang and ,
  • Zhigang Zhu and
  • Yanping Tu
  • + 1 author+ 0 author

30 September 2026

Ballastless track slabs are subjected to complex restraint conditions and operational environments, making deformation-induced cracking a critical factor affecting durability and service performance. Conventional cracking resistance evaluations gener...

(This article belongs to the Section Construction and Building Materials)
  • Article
  • Open Access
25 Citations
3,997 Views
12 Pages

3 March 2023

The paper deals with the effectiveness of various types of polymers (naphthalene formaldehyde, polycarboxylate, and lignosulfonate) as superplasticizers of concrete mixtures based on low-clinker slag Portland cement. Using the mathematical planning e...

(This article belongs to the Section Construction and Building Materials)
  • Article
  • Open Access
783 Views
30 Pages

Defective Gamma–G Family for Cure Fraction Models: Novel Survival Methods with Applications to Cancer Data

  • Cynthia A. V. Tojeiro,
  • Vera L. D. Tomazella,
  • Agatha S. Rodrigues and
  • Pedro R. D. Marinho

17 June 2026

In this paper, we propose two novel defective survival models within the Gamma–G family: the defective Gamma–Gompertz and the defective Gamma–Dagum distributions. In contrast to the corresponding Gamma–G mixture cure formulati...

(This article belongs to the Topic Application of Biostatistics in Medical Sciences and Global Health)
  • Article
  • Open Access
4 Citations
2,473 Views
25 Pages

Investigating on the Pavement Performance of Multi-Source Solid Wastes by Cement and Fly Ash

  • Long Shan,
  • Hongbo Li,
  • Jing Zhao,
  • Xuanshuo Zhang and ,
  • Xinrui Kang,
  • Xing Gao and
  • Zhiyao Zhou
  • + 2 authors+ 0 author

4 October 2023

In order to advance the utilization rate of multi-source solid wastes in the Ningxia region of China, 16 groups of pavement base mixtures were designed with cement and fly ash (FA) as binders, steel slag (SS), silicon manganese slag (SMS), and recycl...

(This article belongs to the Special Issue Industrial Solid Wastes for Construction and Building Materials)
  • Article
  • Open Access
482 Views
36 Pages

12 September 2026

Alkali-activated materials are a sustainable alternative to Portland cement, yet the relative importance of activator and precursor parameters under ambient curing is unquantified, and literature-trained models are rarely validated against independen...

(This article belongs to the Section Building Materials, and Repair & Renovation)
  • Article
  • Open Access
189 Views
20 Pages

26 October 2026

Predicting compressive strength from constituent quantities and curing conditions supports the assessment of candidate mixtures in ultra-high-performance concrete (UHPC) mixture design. Existing machine learning models usually process recorded variab...

(This article belongs to the Special Issue AI-Driven Design and Optimization of Sustainable Construction Materials and Infrastructure)
  • Article
  • Open Access
2 Citations
582 Views
34 Pages

15 July 2026

The compressive strength of ultra-high-performance concrete (UHPC) is jointly influenced by multiple factors, including material composition, mixture proportion parameters, and curing regime. Conventional empirical methods are therefore insufficient...

(This article belongs to the Section Civil Engineering)
  • Article
  • Open Access
4 Citations
1,535 Views
11 Pages

27 September 2025

The curing of silicone networks from dimethylsilanediol and methylsilanetriol chainbuilder–crosslinker precursor mixtures is investigated from combined quantum/molecular mechanics simulations. Upon screening different crosslinker content from 5...

(This article belongs to the Special Issue Silicon-Based Polymers: From Synthesis to Applications)
  • Article
  • Open Access
31 Citations
6,939 Views
12 Pages

Actual 10-Year Survival after Resection of Perihilar Cholangiocarcinoma: What Factors Preclude a Chance for Cure?

  • Anne-Marleen van Keulen,
  • Pim B. Olthof,
  • Matteo Cescon,
  • Alfredo Guglielmi and ,
  • William R. Jarnagin,
  • Silvio Nadalin,
  • Johann Pratschke,
  • Francesca Ratti,
  • Roberto I. Troisi and
  • on behalf of the ‘Perihilar Cholangiocarcinoma Collaboration Group’
  • + 8 authors+ 3 authors

13 December 2021

Complete resection of perihilar cholangiocarcinoma (pCCA) is the only potentially curative treatment. Long-term survival data is rare and prognostic analyses are hindered by the rarity of the disease. This study aimed to determine the cure rate and t...

(This article belongs to the Section Cancer Causes, Screening and Diagnosis)
  • Article
  • Open Access
21 Citations
4,433 Views
16 Pages

Modeling the Impact of Liquid Polymers on Concrete Stability in Terms of a Slump and Compressive Strength

  • Ahmed Salih Mohammed,
  • Wael Emad,
  • Warzer Sarwar Qadir,
  • Rawaz Kurda and ,
  • Kawan Ghafor and
  • Raed Kadhim Faris
  • + 1 author+ 0 author

16 January 2023

It is generally known that the two most crucial elements of concrete that depend on the slump value of the mixture are workability and compressive strength. In addition, slump retention is more delicate than the commonly used slump value since it ref...

(This article belongs to the Special Issue Novel Hybrid Intelligence Techniques in Engineering)
  • Article
  • Open Access
11 Citations
3,313 Views
19 Pages

5 February 2022

Alkali-activated mortars and concretes have been gaining increased attention due to their potential for providing a more sustainable alternative to traditional ordinary Portland cement mixtures. In addition, the inclusion of high volumes of recycled...

(This article belongs to the Collection Alkali‐Activated Materials for Sustainable Construction)
  • Article
  • Open Access
16 Citations
3,609 Views
12 Pages

Effectiveness of Polymer Additives in Concrete for 3D Concrete Printing Using Fly Ash

  • Leonid Dvorkin,
  • Janusz Konkol,
  • Vitaliy Marchuk and
  • Andriy Huts

13 December 2022

The article shows the effectiveness of the use of polymer additives for the production of fine-grained concrete mixtures and concretes based on using coal fly ash, which can be used as working mixtures for a 3D printer. Using mathematical planning of...

(This article belongs to the Special Issue Progress in 3D Printing)
  • Article
  • Open Access
5 Citations
1,862 Views
17 Pages

Dynamic Modulus Regression Models for Cold Recycled Asphalt Mixtures

  • João Meneses,
  • Kamilla Vasconcelos,
  • Kazuo Kuchiishi and
  • Liedi Bernucci

Cold recycling is an advantageous technique from economic and environmental perspectives for asphalt pavement rehabilitation, interventions, and maintenance. This work covered the investigation of dynamic modulus (|E*|) test models and their effects...

(This article belongs to the Special Issue Cold and Warm Techniques for Sustainable Pavement Construction and Maintenance)
  • Article
  • Open Access
3 Citations
1,262 Views
37 Pages

10 April 2026

Pozzolanic concrete demonstrates intricate, highly nonlinear material interactions that pose significant challenges for the accurate prediction of compressive strength (CS). This study introduces a novel, interpretable ensemble machine learning (ML)...

(This article belongs to the Section Artificial Intelligence in Polymer Science)
  • Article
  • Open Access
1 Citations
749 Views
26 Pages

Integrating the Porosity/Binder Index and Machine Learning Approaches for Simulating the Strength and Stiffness of Cemented Soil

  • Jair De Jesús Arrieta Baldovino,
  • Oscar E. Coronado-Hernandez and
  • Yamid E. Nuñez de la Rosa

7 December 2025

This study evaluates the mechanical performance and predictive modeling of fine-grained soils stabilized with crushed aggregate residue (CAR) or crushed limestone waste (CLW) and Portland cement by integrating the porosity–binder index (η/C...

(This article belongs to the Section Construction and Building Materials)
  • Article
  • Open Access
3 Citations
1,135 Views
24 Pages

12 November 2025

Predicting unconfined compressive strength (UCS) is essential for the safety and stability of solid waste-based backfill materials, particularly due to the correlation between strength development and hazardous substance immobilization. This study de...

(This article belongs to the Special Issue AI-Based Material Design, Performance Evaluation and Construction Quality Control of Asphalt Pavement)
  • Article
  • Open Access
9 Citations
3,215 Views
15 Pages

Prediction Models for Mechanical Properties of Cement-Bound Aggregate with Waste Rubber

  • Matija Zvonarić,
  • Mirta Benšić,
  • Ivana Barišić and
  • Tihomir Dokšanović

4 January 2024

The high stiffness of cement-bound aggregate (CBA) is recognized as its main drawback. The stiffness is described by the modulus of elasticity, which is difficult to determine precisely in CBA. Incorporating rubber in these mixtures reduces their sti...

(This article belongs to the Special Issue Development, Characterization, Application and Recycling of Novel Construction Materials)
  • Article
  • Open Access
1 Citations
2,102 Views
27 Pages

Concrete is fundamental to modern construction, comprising 70% of all building materials and supporting an industry projected to reach $15 trillion by 2030. Predicting compressive strength—a key factor for structural safety and resource efficie...

(This article belongs to the Special Issue Sustainable Construction Materials’ Contribution to a Zero-Waste Future)
  • Review
  • Open Access
156 Citations
26,306 Views
58 Pages

A Review on Modeling Cure Kinetics and Mechanisms of Photopolymerization

  • Margit Lang,
  • Stefan Hirner,
  • Frank Wiesbrock and
  • Peter Fuchs

19 May 2022

Photopolymerizations, in which the initiation of a chemical-physical reaction occurs by the exposure of photosensitive monomers to a high-intensity light source, have become a well-accepted technology for manufacturing polymers. Providing significant...

(This article belongs to the Special Issue Recent Developments in Polymerization Kinetics)
  • Article
  • Open Access
1 Citations
777 Views
27 Pages

Accurate prediction of concrete compressive strength remains a challenging problem due to the complex and nonlinear interactions among mixture components and curing conditions. While machine learning approaches have shown promising results, existing...

(This article belongs to the Section Construction Management, and Computers & Digitization)
  • Article
  • Open Access
496 Views
21 Pages

27 August 2026

Waste soil generated by building and underground construction is commonly characterized by high water content and low strength, while conventional cement stabilization entails high cement consumption. This study develops two low-cement binders incorp...

(This article belongs to the Special Issue Advances in Environmentally-Friendly Building Materials in Construction)
  • Article
  • Open Access
9 Citations
6,454 Views
22 Pages

Cold-Setting Inkjet Printed Titania Patterns Reinforced by Organosilicate Binder

  • Marcela Králová,
  • Petr Dzik,
  • Vít Kašpárek,
  • Michal Veselý and
  • Jaroslav Cihlář

11 September 2015

A hybrid organo-silica sol was used as a binder for reinforcing of commercial titanium dioxide nanoparticles (Evonic P25) deposited on glass substrates. The organo-silica binder was prepared by the sol-gel process and mixtures of titania nanoparticle...

(This article belongs to the Special Issue Nano-Structural Photocatalytic Materials: Synthesis, Characterization and Applications)

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