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  • Article
  • Open Access
1,160 Views
17 Pages

MT-Tracker: A Phylogeny-Aware Algorithm for Quantifying Microbiome Transitions Across Scales and Habitats

  • Wenjie Zhu,
  • Yangyang Sun,
  • Weiwen Luo,
  • Guosen Hou,
  • Hao Gao and
  • Xiaoquan Su

16 June 2025

The structural diversity of microbial communities plays a pivotal role in microbiological research and applications. However, the study of microbial transitions has remained challenging due to a lack of effective methods, limiting our understanding o...

(This article belongs to the Special Issue Computational Intelligence for Bioinformatics)
  • Article
  • Open Access
4 Citations
3,511 Views
25 Pages

Compositional Dynamics of Gastrointestinal Tract Microbiomes Associated with Dietary Transition and Feeding Cessation in Lake Sturgeon Larvae

  • Shairah Abdul Razak,
  • Shaley Valentine,
  • Terence Marsh,
  • John Bauman,
  • Norfarhan Mohd-Assaad and
  • Kim T. Scribner

Compromised nutritional conditions associated with dietary transitions and feeding cessation in the wild and during fish aquaculture operations are common and can impact growth and survival. These effects are especially prevalent during early ontogen...

(This article belongs to the Special Issue Microbiomes of Aquatic Organisms)
  • Review
  • Open Access
323 Views
19 Pages

1 October 2026

The oral cavity is a continuous microbial source for the gastrointestinal tract. Adults swallow approximately 0.5–1.5 L of saliva each day, carrying a large and variable bacterial load. Gastric acidity removes most ingested organisms, but survi...

(This article belongs to the Topic Oral Health Management and Disease Treatment)
  • Article
  • Open Access
15 Citations
4,770 Views
14 Pages

The transition from nature to laboratory or mass rearing can impose significant physiological and evolutionary impact on insects. The Queensland fruit fly (also known as ‘Qfly’), Bactrocera tryoni (Froggatt) (Diptera: Tephritidae), is a s...

(This article belongs to the Special Issue Microbiota in Insects)
  • Article
  • Open Access
43 Citations
4,861 Views
13 Pages

The Bladder Microbiome Is Associated with Epithelial–Mesenchymal Transition in Muscle Invasive Urothelial Bladder Carcinoma

  • Wei Tse Li,
  • Anjali S. Iyangar,
  • Rohan Reddy,
  • Jaideep Chakladar,
  • Valmik Bhargava,
  • Kyoko Sakamoto,
  • Weg M. Ongkeko and
  • Mahadevan Rajasekaran

21 July 2021

The intra-tumor microbiome has recently been linked to epithelial–mesenchymal transition (EMT) in a number of cancers. However, the relationship between EMT and microbes in bladder cancer has not been explored. In this study, we profiled the abundanc...

  • Article
  • Open Access
38 Citations
5,455 Views
13 Pages

Earthworms heavily modify the soil microbiome as it passes throughout their guts. However, there are no detailed studies describing changes in the composition, structure and diversity of soil microbiomes during gut transit and once they are released...

(This article belongs to the Special Issue Soil Microbial Diversity and Its Ecological Functions)
  • Article
  • Open Access
24 Citations
9,437 Views
31 Pages

17 May 2019

The human microbiome is an extremely complex ecosystem considering the number of bacterial species, their interactions, and its variability over space and time. Here, we untangle the complexity of the human microbiome for the Irritable Bowel Syndrome...

(This article belongs to the Special Issue Information Theory in Complex Systems)
  • Article
  • Open Access
18 Citations
4,416 Views
18 Pages

Identification of Bacterial Metabolites Modulating Breast Cancer Cell Proliferation and Epithelial-Mesenchymal Transition

  • Gyula Ujlaki,
  • Tünde Kovács,
  • András Vida,
  • Endre Kókai,
  • Boglára Rauch,
  • Szandra Schwarcz,
  • Edit Mikó,
  • Eszter Janka,
  • Adrienn Sipos and
  • Peter Bai
  • + 3 authors

5 August 2023

Breast cancer patients are characterized by the oncobiotic transformation of multiple microbiome communities, including the gut microbiome. Oncobiotic transformation of the gut microbiome impairs the production of antineoplastic bacterial metabolites...

  • Review
  • Open Access
34 Citations
8,488 Views
20 Pages

Exploring the Role of the Gut and Intratumoral Microbiomes in Tumor Progression and Metastasis

  • Aneta Sevcikova,
  • Beata Mladosievicova,
  • Michal Mego and
  • Sona Ciernikova

6 December 2023

Cancer cell dissemination involves invasion, migration, resistance to stressors in the circulation, extravasation, colonization, and other functions responsible for macroscopic metastases. By enhancing invasiveness, motility, and intravasation, the e...

(This article belongs to the Special Issue Microbiota and Cancer 3.0)
  • Article
  • Open Access
141 Citations
9,507 Views
27 Pages

Indolepropionic Acid, a Metabolite of the Microbiome, Has Cytostatic Properties in Breast Cancer by Activating AHR and PXR Receptors and Inducing Oxidative Stress

  • Zsanett Sári,
  • Edit Mikó,
  • Tünde Kovács,
  • Laura Jankó,
  • Tamás Csonka,
  • Gréta Lente,
  • Éva Sebő,
  • Judit Tóth,
  • Dezső Tóth and
  • Péter Bai
  • + 9 authors

25 August 2020

Oncobiotic transformation of the gut microbiome may contribute to the risk of breast cancer. Recent studies have provided evidence that the microbiome secretes cytostatic metabolites that inhibit the proliferation, movement, and metastasis formation...

  • Article
  • Open Access
481 Views
30 Pages

Exploratory Assessment of Oral Microbiome Dysbiosis Associated with Chronic Smokeless Tobacco Use: A Sibling-Based Study

  • Sreekutti S.,
  • Rukhsar Ansari,
  • Rajesh Chaudhari,
  • Anjana Ghelani,
  • Dushyant Dudhagara,
  • Pravin Dudhagara and
  • Vishal Mevada

14 August 2026

Smokeless tobacco (SLT) consumption is a significant risk factor for oral dysbiosis and oral cancer in South Asian countries, including India. However, its impact on oral microbial ecology, functional restructuring, and sex-specific microbial respons...

(This article belongs to the Special Issue Bacterial Molecular Biology: Stress Responses and Adaptation)
  • Review
  • Open Access
10 Citations
2,744 Views
48 Pages

29 October 2025

(1) Background: Oral squamous cell carcinoma (OSCC) is the most common type of head and neck malignancy worldwide. Despite the prevalence of modern diagnostic and prognostic techniques, late diagnosis and resistance to treatment still result in a low...

(This article belongs to the Special Issue Communication and Accessibility in the Tumor Microenvironment as a Therapeutic Target)
  • Article
  • Open Access
465 Views
15 Pages

Short-Term Stability of the Fecal Microbiota in Wild Cavia tschudii During Early Captivity Transition

  • Hugo Frías,
  • Juan José Barrios,
  • Lizeth A. Heredia-Vilchez,
  • Paul Fernandez-Castro,
  • Nilton Luis Murga Valderrama,
  • Segundo Melecio Portocarrero Villegas,
  • Angelo V. Esparraga-Calle,
  • Gleni Tatiana Segura Portocarrero,
  • Jorge L. Maicelo Quintana and
  • José Américo Saucedo-Uriarte
  • + 6 authors

This study evaluated the short-term response of the fecal microbiota of wild Cavia tschudii during its transition from natural conditions to captivity under a standardized alfalfa-based diet. Fecal samples were collected over a 21-day period and anal...

(This article belongs to the Section Gut Microbiota)
  • Review
  • Open Access
483 Views
34 Pages

Integrating Host Transcriptomics and Metagenomics in the Periparturient Dairy Cow: From Molecular Signatures to Host–Microbiome Interfaces

  • Qingshan Ma,
  • Mohamed Tharwat,
  • Abd Ullah,
  • Junjie Liu,
  • Abdulrahman A. Alkheraif and
  • Muhammad Zahoor Khan

26 September 2026

The periparturient or transition period—roughly three weeks before to three weeks after calving—compresses the most severe metabolic, endocrine and immunological demands of the production cycle into a few weeks and accounts for most clini...

(This article belongs to the Special Issue Microbiome and Its Impact on Animal Health and Production)
  • Article
  • Open Access
2 Citations
1,955 Views
25 Pages

Transitions of the Bacteria–Fungi Microbiomes Associated with Different Life Cycle Stages of Dinoflagellate Scrippsiella acuminata

  • Caixia Yue,
  • Zhaoyang Chai,
  • Fengting Li,
  • Lixia Shang,
  • Zhangxi Hu,
  • Yunyan Deng and
  • Ying-Zhong Tang

Dinoflagellates significantly contribute to the carbon fixation and microbial loop in the ocean with high ecological diversity. While the microbial communities associated with the HABs of dinoflagellates have attracted intensive attention in recent y...

(This article belongs to the Special Issue Research on Biology of Dinoflagellates)
  • Article
  • Open Access
1,288 Views
17 Pages

Longitudinal Gut Microbiome Changes Associated with Transitions from C. difficile Negative to C. difficile Positive on Surveillance Tests

  • L. Silvia Munoz-Price,
  • Samantha N. Atkinson,
  • Vy Lam,
  • Blake Buchan,
  • Nathan Ledeboer,
  • Nita H. Salzman and
  • Amy Y. Pan

Clostridioides difficile is an obligate anaerobe and is primarily transmitted via the fecal–oral route. Data characterizing the microbiome changes accompanying transitions from non-colonized to C. difficile colonized subjects are currently lack...

(This article belongs to the Special Issue The Microbiome in Ecosystems)
  • Article
  • Open Access
1 Citations
535 Views
20 Pages

Changes in the Soil Microbiome of Arable Soils in the Permafrost-Affected Zone During Their Transition to a Fallow State

  • Jialu Ma,
  • Timur Nizamutdinov,
  • Sizhong Yang,
  • Xiaodong Wu,
  • Anastasiia Kimeklis,
  • Evgeny Andronov and
  • Evgeny Abakumov

3 June 2026

Agricultural land abandonment is widespread in high-latitude regions, yet its effects on soil microbial communities in permafrost ecosystems remain insufficiently understood. In this study, we used a 0–25 year chronosequence of abandoned soils...

(This article belongs to the Section Ecology Science and Engineering)
  • Article
  • Open Access
202 Citations
51,397 Views
12 Pages

The Effect of Psyllium Husk on Intestinal Microbiota in Constipated Patients and Healthy Controls

  • Jonna Jalanka,
  • Giles Major,
  • Kathryn Murray,
  • Gulzar Singh,
  • Adam Nowak,
  • Caroline Kurtz,
  • Inmaculada Silos-Santiago,
  • Jeffrey M. Johnston,
  • Willem M. de Vos and
  • Robin Spiller

Psyllium is a widely used treatment for constipation. It traps water in the intestine increasing stool water, easing defaecation and altering the colonic environment. We aimed to assess the impact of psyllium on faecal microbiota, whose key role in g...

(This article belongs to the Special Issue Microbiota, Food and Health)
  • Article
  • Open Access
12 Citations
4,972 Views
46 Pages

Gut Microbiome Modulation and Health Benefits of a Novel Fucoidan Extract from Saccharina latissima: A Double-Blind, Placebo-Controlled Trial

  • Gissel Garcia,
  • Josanne Soto,
  • Carmen Valenzuela,
  • Mirka Bernal,
  • Jesús Barreto,
  • María de la C. Luzardo,
  • Raminta Kazlauskaite,
  • Neil Waslidge,
  • Charles Bavington and
  • Raúl de Jesús Cano

This randomized, double-blind, placebo-controlled, three-arm clinical trial evaluated the effects of a proprietary bioactive fucoidan-rich extract derived from Saccharina latissima (SLE-F) on gut microbial composition and function in healthy adults....

(This article belongs to the Special Issue Gut Microbiota in Health and Diseases: The Role of Pro-/Pre-/Syn-/Post-Biotics in the Gut–Liver–Brain Axis)
  • Systematic Review
  • Open Access
17 Citations
44,259 Views
29 Pages

Benefits of Kombucha Consumption: A Systematic Review of Clinical Trials Focused on Microbiota and Metabolic Health

  • Gabriela Macedo Fraiz,
  • Dandara Baia Bonifácio,
  • Rayanne Santos de Paulo,
  • Carolynne Martins Teixeira,
  • Hércia Stampini Duarte Martino,
  • Frederico Augusto Ribeiro de Barros,
  • Fermín I. Milagro and
  • Josefina Bressan

Background: Fermented foods rich in bioactive compounds have been proposed as potential strategy to combat non-communicable diseases. Among them is kombucha, a beverage fermented from sugared Camellia sinensis tea by a symbiotic culture of bacteria a...

(This article belongs to the Section Probiotic Strains and Fermentation)
  • Article
  • Open Access
2,210 Views
24 Pages

24 April 2026

Although prebiotics and postbiotics support gastrointestinal health, evidence for their combined effects in dogs remains limited. This study evaluated a novel prebiotic and postbiotic supplement in healthy dogs undergoing a dietary transition. Thirty...

  • Article
  • Open Access
1,317 Views
21 Pages

26 May 2026

Seed-associated endophytes become active during germination, playing important roles as early colonizers of plant tissues and contributing to plant health while residing in a protective niche. In this study, we characterized a wheat-derived bacterial...

  • Article
  • Open Access
432 Views
19 Pages

Host-Dependent Endophytes as a Resilient Biological Reservoir: Niche-Specific Expansion and Holobiont Reassembly in Grapevine

  • Jing-Xiu Tang,
  • Yu-Tao Wang,
  • Hong-Yan Hu,
  • Jia-Xin Zhou,
  • Rui-Yu Yang,
  • Qiu-Yue Zhang,
  • Hao Sun,
  • Xiao-Xia Pan and
  • Ming-Zhi Yang

Plants and their endophytic microbiota form a functional holobiont, wherein host-dependent endophytes (HDEs) are proposed to serve as persistent microbial components associated with host continuity. Using long-term in vitro grapevine plantlets, we in...

(This article belongs to the Section Plant Microbe Interactions)
  • Article
  • Open Access
303 Views
15 Pages

Habitat transition can reorganize plant-associated microbial communities, yet whether rhizosphere bacteria and fungi respond similarly to the transition from native to introduced habitats remains unclear. Here, we investigated this question in the en...

(This article belongs to the Section Environmental Microbiology)
  • Article
  • Open Access
14 Citations
4,327 Views
12 Pages

Seasons Influence the Native Gut Microbiome of Lake Trout Salvelinus namaycush

  • Pascale Savard,
  • Tim Fernandes,
  • Amy Dao,
  • Bailey McMeans and
  • Cassandre Sara Lazar

The fish gut microbiome plays an essential role in the host’s development and survival. Environmental factors can shape the gut microbiome and potentially mediate physiological performance. Seasonal environments that experience regular abiotic...

  • Review
  • Open Access
34 Citations
5,029 Views
15 Pages

Current Understanding of Microbiomes in Cancer Metastasis

  • Jiaqi Liu,
  • Feiyang Luo,
  • Liyan Wen,
  • Zhanyi Zhao and
  • Haitao Sun

22 March 2023

Cancer has been the first killer that threatens people’s lives and health. Despite recent improvements in cancer treatment, metastasis continues to be the main reason for death from cancer. The functions of microbiome in cancer metastasis have...

(This article belongs to the Section Cancer Metastasis)
  • Review
  • Open Access
17 Citations
6,355 Views
18 Pages

Glycan Utilisation and Function in the Microbiome of Weaning Infants

  • Starin McKeen,
  • Wayne Young,
  • Karl Fraser,
  • Nicole C. Roy and
  • Warren C. McNabb

Glycans are present exogenously in the diet, expressed and secreted endogenously by host cells, and produced by microbes. All of these processes result in them being available to the gut microbiome, firmly placing glycans at the interface of diet&nda...

(This article belongs to the Special Issue Gastrointestinal Microbiota Impacts Human Health and Disease)
  • Review
  • Open Access
8 Citations
7,999 Views
26 Pages

Diet, the Gut Microbiome, and Estrogen Physiology: A Review in Menopausal Health and Interventions

  • Michelle Jing Sin Lim,
  • Elvina Parlindungan,
  • E’ein See,
  • Ching Hwee Gan,
  • Rachel Yap and
  • Germaine Jia Min Yong

26 March 2026

Menopause represents a key transitional phase in women’s health, characterized by declining estrogen levels and increased risk for cardiometabolic, musculoskeletal, and urogenital disorders. Beyond its endocrine roots, emerging evidence highlig...

(This article belongs to the Special Issue The Role of Diet and Microbiome in Peri/Menopause)
  • Review
  • Open Access
20 Citations
6,041 Views
21 Pages

The Intestinal Microbiome after Traumatic Injury

  • Jennifer A. Munley,
  • Stacey L. Kirkpatrick,
  • Gwendolyn S. Gillies,
  • Letitia E. Bible,
  • Philip A. Efron,
  • Ravinder Nagpal and
  • Alicia M. Mohr

The intestinal microbiome plays a critical role in host immune function and homeostasis. Patients suffering from—as well as models representing—multiple traumatic injuries, isolated organ system trauma, and various severities of traumatic...

(This article belongs to the Special Issue Gut Microbiota: Health, Clinical & Beyonds)
  • Article
  • Open Access
9 Citations
4,913 Views
26 Pages

Physicochemical Properties and Microbiome of Vineyard Soils from DOP Ribeiro (NW Spain) Are Influenced by Agricultural Management

  • Pilar Blanco,
  • Isaac Rodríguez,
  • Victoria Fernández-Fernández,
  • María Ramil,
  • David Castrillo,
  • Marta Acín-Albiac,
  • Irene Adamo,
  • Clara Fernández-Trujillo,
  • Beatriz García-Jiménez and
  • Flora Alonso-Vega
  • + 4 authors

Agricultural management influences the soil ecosystem by affecting its physicochemical properties, residues of pesticides and microbiome. As vineyards grow crops with the highest incidence of pesticides, the aim of this study was to evaluate the impa...

(This article belongs to the Special Issue Advances in Soil Microbiome 2.0)
  • Article
  • Open Access
1 Citations
2,699 Views
15 Pages

Using the Gut Microbiome to Assess Stocking Efforts of the Endangered Pallid Sturgeon, Scaphirhynchus albus

  • Sarah Gaughan,
  • John A. Kyndt,
  • Justin D. Haas,
  • Kirk D. Steffensen,
  • Patrick M. Kočovský and
  • Kevin L. Pope

22 January 2023

The endangered Pallid Sturgeon, Scaphirhynchus albus, has been actively managed to prevent population declines, including stocking of hatchery-raised fish. The gut microbiome plays an innate role in an organism’s absorption of nutrients by incr...

(This article belongs to the Section Microbiology)
  • Article
  • Open Access
18 Citations
9,262 Views
14 Pages

The Native Hawaiian Insect Microbiome Initiative: A Critical Perspective for Hawaiian Insect Evolution

  • Kirsten E. Poff,
  • Heather Stever,
  • Jonathan B. Reil,
  • Priscilla Seabourn,
  • Alexander J. Ching,
  • Sayaka Aoki,
  • Mitchel Logan,
  • Jennifer R. Michalski,
  • Jessika Santamaria and
  • Gordon M. Bennett
  • + 5 authors

19 December 2017

Insects associate with a diversity of microbes that can shape host ecology and diversity by providing essential biological and adaptive services. For most insect groups, the evolutionary implications of host–microbe interactions remain poorly underst...

  • Review
  • Open Access
35 Citations
12,434 Views
23 Pages

Infant Complementary Feeding of Prebiotics for the Microbiome and Immunity

  • Starin McKeen,
  • Wayne Young,
  • Jane Mullaney,
  • Karl Fraser,
  • Warren C. McNabb and
  • Nicole C. Roy

9 February 2019

Complementary feeding transitions infants from a milk-based diet to solid foods, providing essential nutrients to the infant and the developing gut microbiome while influencing immune development. Some of the earliest microbial colonisers readily fer...

(This article belongs to the Special Issue Diet and Immune Function)
  • Review
  • Open Access
57 Citations
9,812 Views
14 Pages

Risk Factors for Gut Dysbiosis in Early Life

  • Kimberley Parkin,
  • Claus T. Christophersen,
  • Valerie Verhasselt,
  • Matthew N. Cooper and
  • David Martino

Dysbiosis refers to a reduction in microbial diversity, combined with a loss of beneficial taxa, and an increase in pathogenic microorganisms. Dysbiosis of the intestinal microbiota can have a substantial effect on the nervous and immune systems, con...

(This article belongs to the Section Systems Microbiology)
  • Review
  • Open Access
4 Citations
3,824 Views
31 Pages

This review outlines technological advances in pathogen identification and describes the development and evolution of next-generation sequencers that can be applied to the ocular microbiome. Traditional methods such as culture and PCR have limitation...

(This article belongs to the Special Issue Advances in Bacterial Genetics)
  • Article
  • Open Access
313 Views
20 Pages

This study aimed to investigate the microbiome profile of Culex pipiens, the most abundant mosquito and pathogen vector in the Palearctic, and to find microbiome region and ecotype specificity. The taxon Cx. pipiens includes two ecotypes—pipien...

  • Review
  • Open Access
21 Citations
7,655 Views
32 Pages

1 August 2023

Chronic obstructive pulmonary disease (COPD) and lung cancer 17 are two of the most prevalent and debilitating respiratory diseases worldwide, both associated with high morbidity and mortality rates. As major global health concerns, they impose a sub...

(This article belongs to the Special Issue Metal-Based Complexes in Cancer 2.0)
  • Article
  • Open Access
28 Citations
5,118 Views
17 Pages

23 April 2024

The gut microbiome significantly influences the health and productivity of silkworms (Bombyx mori), the cornerstone of sericulture. With the increasing use of cost-effective artificial diets in sericulture, it is crucial to understand how these diets...

(This article belongs to the Special Issue Relationships between Animal Hosts and Microbiota, Animal Health and Response to Diseases)
  • Article
  • Open Access
8 Citations
3,930 Views
10 Pages

Integrating the Gut Microbiome and Stress-Diathesis to Explore Post-Trauma Recovery: An Updated Model

  • Manasi Murthy Mittinty,
  • Joshua Y. Lee,
  • David M. Walton,
  • Emad M. El-Omar and
  • James M. Elliott

Musculoskeletal conditions of traumatic and non-traumatic origin represent an ongoing health challenge. While the last three decades have seen significant advancement in our understanding of musculoskeletal conditions, the mechanisms of a delayed or...

  • Review
  • Open Access
7 Citations
2,753 Views
28 Pages

Harnessing Microbiome-Mediated and Macrophage-Driven Mechanisms for Oral Wound Healing

  • Keerthi Priya Chinniampalayam Sekar,
  • Bianca Schmiliver,
  • Paige Elizabeth Pieterick,
  • Tim Cha,
  • Helly A. Patel,
  • Hope Robinson,
  • Prashant Kumar,
  • David T. Wu,
  • Rheinallt Jones and
  • Steven Goudy

Oral mucosa healing is a complex process that involves the innate wound healing system, including the coagulation cascade, extracellular matrix remodeling, immune cell responses, and fibroblast and epithelial responses, within the context of a dynami...

(This article belongs to the Section Microbiomes)
  • Article
  • Open Access
29 Citations
6,632 Views
19 Pages

Microbiome of the Queensland Fruit Fly through Metamorphosis

  • Rajib Majumder,
  • Brodie Sutcliffe,
  • Phillip W. Taylor and
  • Toni A. Chapman

Bactrocera tryoni (Froggatt) (Queensland fruit fly, or “Qfly”) is a highly polyphagous tephritid fruit fly and a serious economic pest in Australia. Qfly biology is intimately linked to the bacteria and fungi of its microbiome. While ther...

(This article belongs to the Section Systems Microbiology)
  • Article
  • Open Access
1 Citations
590 Views
22 Pages

Continental-Scale Climatic Zones Drive Reorganization of Lake Sediment Microbiome: Diversity, Assembly and Interaction Networks

  • Fanjin Ye,
  • Shuai Lu,
  • Yanfang Tian,
  • Pengsong Li,
  • Ziqing Deng,
  • Peng Gao,
  • Hongjie Gao and
  • Xiaoling Liu

Global climate change has altered temperature regimes, hydrological stability, and redox dynamics in inland waters, yet the continental-scale impact of these alterations on sediment microbiomes remains poorly understood. Here, we compiled 562 publicl...

(This article belongs to the Section Environmental Microbiology)
  • Article
  • Open Access
712 Views
27 Pages

Cervicovaginal Microbiome Signatures Across Cervical Disease States: A Prospective Cross-Sectional Analysis

  • Alexandru Hamod,
  • Oancea Mihaela,
  • Mihaela Grigore,
  • Ingrid-Andrada Vasilache,
  • Ramona-Gabriela Ursu,
  • Razvan Popovici,
  • Ana-Maria Grigore,
  • Ludmila Lozneanu,
  • Dan-Constantin Andronic and
  • Manuela Ciocoiu
  • + 1 author

Background/Objectives: The cervicovaginal microbiome has emerged as a critical determinant of cervical health. In this study, we aimed to characterize the cervicovaginal microbiome across a spectrum of cervical health states and to identify community...

(This article belongs to the Section Diagnostic Microbiology and Infectious Disease)
  • Article
  • Open Access
37 Citations
4,326 Views
15 Pages

Diversity in the Extracellular Vesicle-Derived Microbiome of Tissues According to Tumor Progression in Pancreatic Cancer

  • Jin-Yong Jeong,
  • Tae-Bum Kim,
  • Jinju Kim,
  • Hwi Wan Choi,
  • Eo Jin Kim,
  • Hyun Ju Yoo,
  • Song Lee,
  • Hye Ryeong Jun,
  • Wonbeak Yoo and
  • Eunsung Jun
  • + 2 authors

19 August 2020

This study was conducted to identify the composition and diversity of the microbiome in tissues of pancreatic cancer and to determine its role. First, extracellular vesicles (EVs) were obtained from the paired tumor and normal tissues, and 16s rRNA g...

(This article belongs to the Section Cancer Biomarkers)
  • Review
  • Open Access
38 Citations
6,792 Views
20 Pages

Impact of Early Weaning on Development of the Swine Gut Microbiome

  • Benoit St-Pierre,
  • Jorge Yair Perez Palencia and
  • Ryan S. Samuel

Considering that pigs are naturally weaned between 12 and 18 weeks of age, the common practice in the modern swine industry of weaning as early as between two and four weeks of age increases challenges during this transition period. Indeed, young pig...

(This article belongs to the Special Issue Latest Review Papers in Gut Microbiota 2023)
  • Review
  • Open Access
625 Views
27 Pages

14 August 2026

The growing demand for sustainable and nutritionally optimized protein sources has positioned edible insects as promising platforms for next-generation food and feed systems. Although insect composition varies with diet, the deliberate engineering of...

(This article belongs to the Special Issue Insects as Food: Advances in Edible Insect Research and Applications)
  • Review
  • Open Access
68 Citations
17,407 Views
23 Pages

Gut Microbiota and Time-Restricted Feeding/Eating: A Targeted Biomarker and Approach in Precision Nutrition

  • Falak Zeb,
  • Tareq Osaili,
  • Reyad Shakir Obaid,
  • Farah Naja,
  • Hadia Radwan,
  • Leila Cheikh Ismail,
  • Hayder Hasan,
  • Mona Hashim,
  • Iftikhar Alam and
  • MoezAllslam Ezzat Faris
  • + 1 author

4 January 2023

Each individual has a unique gut microbiota; therefore, the genes in our microbiome outnumber the genes in our genome by about 150 to 1. Perturbation in host nutritional status influences gut microbiome composition and vice versa. The gut microbiome...

(This article belongs to the Section Nutrition and Metabolism)
  • Review
  • Open Access
3,389 Views
21 Pages

The Gut Microbiome as a Key Determinant of the Heritability of Body Mass Index

  • Thomas M. Barber,
  • Stefan Kabisch,
  • Andreas F. H. Pfeiffer and
  • Martin O. Weickert

18 May 2025

The pathogenesis of obesity is complex and incompletely understood, with an underlying interplay between our genetic architecture and obesogenic environment. The public understanding of the development of obesity is shrouded in myths with widespread...

(This article belongs to the Special Issue Interaction Between Gut Microbiota and Obesity)
  • Article
  • Open Access
11 Citations
11,539 Views
12 Pages

Fresh Food Consumption Increases Microbiome Diversity and Promotes Changes in Bacteria Composition on the Skin of Pet Dogs Compared to Dry Foods

  • Kennedy Leverett,
  • Rodrigo Manjarín,
  • Erica Laird,
  • Diana Valtierra,
  • Tasha M. Santiago-Rodriguez,
  • Renan Donadelli and
  • Gerardo Perez-Camargo

22 July 2022

The skin is the first barrier the body has to protect itself from the environment. There are several bacteria that populate the skin, and their composition may change throughout the dog’s life due to several factors, such as environmental chang...

(This article belongs to the Collection The Role of Nutrition in Maintaining Well-Being and Health of Dogs and Cats)
  • Review
  • Open Access
2 Citations
938 Views
27 Pages

22 June 2026

The gut microbiota is recognized as a programmable metabolic organ that governs systemic homeostasis. Recent advances (2023–2025) have pivoted Type 2 Diabetes Mellitus (T2DM) research from a host-centric perspective toward a failure of bidirect...

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