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3,296 Results Found

  • Article
  • Open Access
1,648 Views
20 Pages

Diagnostic for Volatility and Local Influence Analysis for the Vasicek Model

  • Manuel Galea,
  • Alonso Molina and
  • Isabelle S. Beaudry

The Ornstein–Uhlenbeck process is widely used in modeling biological systems and, in financial engineering, is commonly employed to describe the dynamics of interest rates, currency exchange rates, and asset price volatilities. As in any stocha...

  • Article
  • Open Access
9 Citations
6,020 Views
17 Pages

29 November 2022

China has the world’s most extensive vocational education and training (VET) system, and VET teachers are central to training high-quality technical and skilled workers. This study aimed to explore the factors influencing VET teachers’ pr...

  • Article
  • Open Access
3 Citations
3,250 Views
19 Pages

Data-Influence Analytics in Predictive Models Applied to Asthma Disease

  • Alejandra Tapia,
  • Viviana Giampaoli,
  • Víctor Leiva and
  • Yuhlong Lio

15 September 2020

Asthma is one of the most common chronic diseases around the world and represents a serious problem in human health. Predictive models have become important in medical sciences because they provide valuable information for data-driven decision-making...

  • Article
  • Open Access
1,026 Views
32 Pages

New Flexible Asymmetric Log-Birnbaum–Saunders Nonlinear Regression Model with Diagnostic Analysis

  • Guillermo Martínez-Flórez,
  • Inmaculada Barranco-Chamorro and
  • Héctor W. Gómez

23 August 2024

A nonlinear log-Birnbaum–Saunders regression model with additive errors is introduced. It is assumed that the error term follows a flexible sinh-normal distribution, and therefore it can be used to describe a variety of asymmetric, unimodal, an...

  • Article
  • Open Access
1 Citations
1,438 Views
13 Pages

Influence of Covariates on 18F-FDG PET/CT Diagnostic Accuracy for Liver Metastasis

  • Vincent Habouzit,
  • Anthime Flaus,
  • Jean-Marc Phelip,
  • Sylvain Grange,
  • Bertrand Le Roy,
  • Rémi Grange and
  • Nathalie Prévot

(1) Background: 18F-FDG PET/CT diagnostic accuracy for liver metastasis (LM) could be influenced by technical parameters, lesion size, and the patient’s covariates. This retrospective study aimed to evaluate these covariates’ impact on PE...

  • Article
  • Open Access
3 Citations
2,783 Views
11 Pages

Introduction: Comparing imaging examinations with those previously obtained is considered mandatory in imaging guidelines. To our knowledge, no studies are available on neither the influence, nor the sequence, of prior imaging and reports on diagnost...

  • Article
  • Open Access
2 Citations
2,013 Views
11 Pages

24 October 2021

There is a possibility that renal dysfunction may potentially reduce the diagnostic power of the laboratory parameters Tn, NT-proBNP and sFLC levels, used in the current prognostic classification of AL amyloidosis and the diagnosis of heart involveme...

  • Article
  • Open Access
2 Citations
2,344 Views
19 Pages

In diagnostic accuracy studies, the test of interest is typically applied only once in each patient. This paper illustrates some possibilities that arise when diagnoses are carried out by a sufficiently large number of multiple raters. In a dental st...

  • Article
  • Open Access
1 Citations
2,414 Views
11 Pages

Influence of Left Ventricular Diastolic Dysfunction on the Diagnostic Performance of Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve

  • Zhixin Xie,
  • Tianlong Wu,
  • Jing Mu,
  • Ping Zhang,
  • Xuan Wang,
  • Tao Liang,
  • Yihan Weng,
  • Jianfang Luo and
  • Huimin Yu

21 February 2023

Objectives: Our study aimed to demonstrate the influence of left ventricular (LV) diastolic dysfunction on the diagnostic performance of coronary computed tomography angiography-derived fractional flow reserve (CT-FFR). Methods: One hundred vessels f...

  • Article
  • Open Access
6 Citations
4,107 Views
27 Pages

13 March 2023

The capital asset pricing model (CAPM) is often based on the Gaussianity or normality assumption. However, such an assumption is frequently violated in practical situations. In this paper, we introduce the symmetric CAPM considering distributions wit...

  • Article
  • Open Access
2 Citations
2,474 Views
16 Pages

24 April 2024

Non-invasive diagnostics are crucial for the timely detection of renal cell carcinoma (RCC), significantly improving survival rates. Despite advancements, specific lipid markers for RCC remain unidentified. We aimed to discover and validate potent pl...

  • Article
  • Open Access
6 Citations
3,594 Views
13 Pages

Patterns of Pretreatment Diagnostic Assessment in Patients Treated with Stereotactic Body Radiation Therapy (SBRT) for Non-Small Cell Lung Cancer (NSCLC): Special Characteristics in the COVID Pandemic and Influence on Outcomes

  • Felix-Nikolai Oschinka Jegor Habermann,
  • Daniela Schmitt,
  • Thomas Failing,
  • Jann Fischer,
  • David Alexander Ziegler,
  • Laura Anna Fischer,
  • Niklas Josua Alt,
  • Julian Muster,
  • Sandra Donath and
  • Leif Hendrik Dröge
  • + 6 authors

13 February 2022

The pandemic raised a discussion about the postponement of medical interventions for non-small cell lung cancer (NSCLC). We analyzed the characteristics of pretreatment diagnostic assessment in the pandemic and the influence of diagnostic assessment...

  • Brief Report
  • Open Access
11 Citations
3,937 Views
9 Pages

Influence of Diagnostic Delay on Survival Rates for Patients with Colorectal Cancer

  • María Padilla-Ruiz,
  • María Morales-Suárez-Varela,
  • Francisco Rivas-Ruiz,
  • Julia Alcaide,
  • Esperanza Varela-Moreno,
  • Irene Zarcos-Pedrinaci,
  • Teresa Téllez,
  • Nerea Fernández-de Larrea-Baz,
  • Marisa Baré and
  • on behalf of CARESS-CCR Study Group
  • + 5 authors

Colorectal cancer affects men and women alike. Sometimes, due to clinical-pathological factors, the absence of symptoms or the failure to conduct screening tests, its diagnosis may be delayed. However, it has not been conclusively shown that such a d...

  • Article
  • Open Access
10 Citations
2,618 Views
14 Pages

Research of Prostate Cancer Urinary Diagnostic Biomarkers by Proteomics: The Noteworthy Influence of Inflammation

  • Elisa Bellei,
  • Stefania Caramaschi,
  • Giovanna A. Giannico,
  • Emanuela Monari,
  • Eugenio Martorana,
  • Luca Reggiani Bonetti and
  • Stefania Bergamini

Nowadays, in the case of suspected prostate cancer (PCa), tissue needle biopsy remains the benchmark for diagnosis despite its invasiveness and poor tolerability, as serum prostate-specific antigen (PSA) is limited by low specificity. The aim of this...

  • Brief Report
  • Open Access
4 Citations
2,437 Views
12 Pages

When making decisions under uncertainty, people in all walks of life, including highly trained medical professionals, tend to resort to using ‘mental shortcuts’, or heuristics. Anchoring-and-adjustment (AAA) is a well-known heuristic in w...

  • Review
  • Open Access
9 Citations
6,020 Views
36 Pages

The Other Side of Alzheimer’s Disease: Influence of Metabolic Disorder Features for Novel Diagnostic Biomarkers

  • Chiara Argentati,
  • Ilaria Tortorella,
  • Martina Bazzucchi,
  • Carla Emiliani,
  • Francesco Morena and
  • Sabata Martino

6 September 2020

Nowadays, the amyloid cascade hypothesis is the dominant model to explain Alzheimer’s disease (AD) pathogenesis. By this hypothesis, the inherited genetic form of AD is discriminated from the sporadic form of AD (SAD) that accounts for 85&ndash...

  • Article
  • Open Access
12 Citations
2,544 Views
11 Pages

[18F]Fluorodeoxyglucose positron emission tomography (FDG-PET) is increasingly used to demonstrate inflammation in specific sites typical for polymyalgia rheumatica (PMR). Scoring systems based on FDG uptake have been proposed to increase diagnostic...

  • Article
  • Open Access
7 Citations
3,821 Views
11 Pages

Prediction of Myometrial Invasion in Stage I Endometrial Cancer by MRI: The Influence of Surgical Diagnostic Procedure

  • Wei-Chun Chen,
  • Le-Tien Hsu,
  • Yu-Ting Huang,
  • Yu-Bin Pan,
  • Shir-Hwa Ueng,
  • Hung-Hsueh Chou and
  • Ting-Chang Chang

30 June 2021

Young women with endometrial cancer (EC) can choose fertility-sparing treatment for stage 1A disease without myometrial invasion (MI). The surgical diagnostic procedure (SDP) may affect the accuracy of magnetic resonance imaging (MRI) to assess MI. H...

  • Feature Paper
  • Review
  • Open Access
2 Citations
3,725 Views
17 Pages

4 December 2024

This literature review focuses on diagnostics of equine asthma (EA), possible influencing factors on diagnostic techniques and latest developments in diagnosing horses during EA remission or with subclinical disease. Routine EA diagnostics include a...

  • Article
  • Open Access
19 Citations
4,157 Views
21 Pages

A New Quantile Regression Model and Its Diagnostic Analytics for a Weibull Distributed Response with Applications

  • Luis Sánchez,
  • Víctor Leiva,
  • Helton Saulo,
  • Carolina Marchant and
  • José M. Sarabia

1 November 2021

Standard regression models focus on the mean response based on covariates. Quantile regression describes the quantile for a response conditioned to values of covariates. The relevance of quantile regression is even greater when the response follows a...

  • Opinion
  • Open Access
1 Citations
1,693 Views
8 Pages

8 August 2023

The AIDS and COVID-19 pandemics demonstrated that nations at similar economic development levels varied widely in their capacity to protect the health of their residents. For AIDS, Britain and Australia brought gay representatives into official couns...

  • Article
  • Open Access
1 Citations
1,514 Views
18 Pages

23 June 2023

In this paper, we propose a nonlinear regression model with exponentiated skew-elliptical errors distributed, which can be fitted to datasets with high levels of asymmetry and kurtosis. Maximum likelihood estimation procedures in finite samples are d...

  • Article
  • Open Access
7 Citations
3,186 Views
17 Pages

Characterizing Variability in Lung Cancer Outcomes and Influence of a Lung Diagnostic Assessment Program in Southeastern Ontario, Canada

  • Shahad AlGhamdi,
  • Weidong Kong,
  • Michael Brundage,
  • Elizabeth A. Eisenhauer,
  • Christopher M. Parker and
  • Geneviève C. Digby

9 May 2023

Introduction: Regional variability in lung cancer (LC) outcomes exists across Canada, including in the province of Ontario. The Lung Diagnostic Assessment Program (LDAP) in southeastern (SE) Ontario is a rapid-assessment clinic that expedites the man...

  • Article
  • Open Access
1,344 Views
28 Pages

Influence of the Neural Network Morphology Symmetry on the Complex Dynamic Objects’ Diagnostics

  • Serhii Vladov,
  • Victoria Vysotska,
  • Viktor Vasylenko,
  • Vasyl Lytvyn,
  • Mariia Nazarkevych and
  • Olha Fedevych

27 December 2024

In this article, to study the influence of neural networks’ morphology symmetry, a mathematical model is developed that considers dynamic symmetry for diagnosing complex dynamic objects. The developed mathematical model includes the symmetric a...

  • Article
  • Open Access
2 Citations
4,616 Views
14 Pages

13 January 2023

Brand names on food packaging and the diagnosticity of brand names have notable effects on consumer preferences. However, their effects on healthy food consumption are not clear. The objective of this study was to investigate the effect of healthy br...

  • Article
  • Open Access
1 Citations
1,127 Views
13 Pages

14 September 2025

Background: Tuberculosis (TB) remains a leading cause of death among people living with HIV (PLWH), yet diagnostic methods vary in accuracy, accessibility, and implementation. Understanding how diagnostic modality influences TB detection is essential...

  • Article
  • Open Access
3 Citations
2,920 Views
12 Pages

Influence of Apnea Hypopnea Index and the Degree of Airflow Limitation on Endothelial Function in Patients Undergoing Diagnostic Coronary Angiography

  • Dorota Ochijewicz,
  • Adam Rdzanek,
  • Tadeusz Przybyłowski,
  • Renata Rubinsztajn,
  • Monika Budnik,
  • Ewa Pędzich,
  • Katarzyna Białek-Gosk,
  • Piotr Bielicki and
  • Agnieszka Kapłon-Cieślicka

17 March 2022

Background: Obstructive sleep apnea is associated with an increased prevalence of cardiovascular disease. The mechanism of these associations is not completely understood. We aimed to investigate the association of the apnea hypopnea index and the de...

  • Systematic Review
  • Open Access
13 Citations
13,598 Views
13 Pages

A Systematic Review of the Influence of Bovine Colostrum Supplementation on Leaky Gut Syndrome in Athletes: Diagnostic Biomarkers and Future Directions

  • Hanna Dziewiecka,
  • Harpal S. Buttar,
  • Anna Kasperska,
  • Joanna Ostapiuk-Karolczuk,
  • Małgorzata Domagalska,
  • Justyna Cichoń and
  • Anna Skarpańska-Stejnborn

17 June 2022

Background: Bovine colostrum (BC) contains a myriad of bioactive molecules that are renowned for possessing unique medicinal benefits in children and adults, and BC supplements are considered safe and cost-effective options to manage/prevent the inci...

  • Systematic Review
  • Open Access
13 Citations
3,986 Views
13 Pages

12 September 2023

Early detection and accurate prediction of the risk of early childhood caries (ECC) are essential for effective prevention and management. This systematic review aims to assess the performance and applicability of machine learning algorithms in ECC p...

  • Article
  • Open Access
6 Citations
4,720 Views
18 Pages

Influence of Sedation Level and Ventilation Status on the Diagnostic Validity of Delirium Screening Tools in the ICU—An International, Prospective, Bi-Center Observational Study (IDeAS)

  • Flavio E. Nacul,
  • Nicolas Paul,
  • Claudia D. Spies,
  • Henriette Sechting,
  • Thomas Hecht,
  • Jörn S. Dullinger,
  • Sophie K. Piper,
  • Alawi Luetz,
  • Felix S. Balzer and
  • Björn Weiss
  • + 5 authors

13 August 2020

Background and objectives: The use of delirium screening instruments (DSIs) is recommended in critical care practice for a timely detection of delirium. We hypothesize that the patient-related factors “level of sedation” and “mechan...

  • Article
  • Open Access
15 Citations
3,363 Views
17 Pages

Low Ionosphere under Influence of Strong Solar Radiation: Diagnostics and Modeling

  • Vladimir A. Srećković,
  • Desanka M. Šulić,
  • Ljubinko Ignjatović and
  • Veljko Vujčić

4 August 2021

Solar flares (SFs) and intense radiation can generate additional ionization in the Earth’s atmosphere and affect its structure. These types of solar radiation and activity create sudden ionospheric disturbances (SIDs), affect electronic equipment on...

  • Editorial
  • Open Access
3 Citations
2,451 Views
2 Pages

24 March 2023

The study of solar-influenced space weather and, consequently, extreme weather events, climate change, protection, and preservation are of particular interest in modern science because they are acknowledged as being important for sustainable developm...

  • Article
  • Open Access
200 Views
12 Pages

AI in Diagnostic Radiology: What Happens When Algorithms Are Updated

  • Martine Rustøen Skregelid,
  • Kasim Ibrahim-Pur,
  • Flemming Skjøth,
  • Malene Roland Vils Pedersen and
  • Helle Precht

Background: Interpretation of radiographs is prone to diagnostic errors. Artificial intelligence (AI) has shown promising results in fracture detection, although systematic evaluation of software updates remains limited. This study compares the diagn...

  • Article
  • Open Access
2 Citations
1,826 Views
12 Pages

Stigmatizing effects of psychological diagnosis in children

  • Mª del Mar Montoya-Rodríguez and
  • Francisco-Javier Molina-Cobos

Despite the known advantages of the classification of psychological disorders, using formal diagnostic could reduce a story of life and way of behaving to a mere diagnostic label, becoming a tautological explanation that ignores the true explanation...

  • Article
  • Open Access
57 Citations
10,606 Views
13 Pages

Augmented reality (AR) enables consumers to browse and try products virtually by providing additional information and functionality to mobile shopping. Retailers continue to develop AR technology to engage consumers and enhance their digital shopping...

  • Article
  • Open Access
1 Citations
1,500 Views
13 Pages

Health and Liver Diagnostic Markers Influencing Glycemia in Subjects with Prediabetes: Preview Study

  • Omar Ramos-Lopez,
  • Diego Martinez-Urbistondo,
  • Santiago Navas-Carretero,
  • Ruixin Zhu,
  • Maija Huttunen-Lenz,
  • Gareth Stratton,
  • Teodora Handjieva-Darlenska,
  • Svetoslav Handjiev,
  • Jouko Ensio Sundvall and
  • J. Alfredo Martinez
  • + 13 authors

23 December 2024

Introduction: Glucose homeostasis may be dependent on liver conditions and influence health-related markers and quality of life (QoL) objective measurements. This study aimed to analyze the interactions of glycemia with liver and health status in a p...

  • Review
  • Open Access
28 Citations
9,944 Views
25 Pages

Subgroup-Specific Diagnostic, Prognostic, and Predictive Markers Influencing Pediatric Medulloblastoma Treatment

  • Sutapa Ray,
  • Nagendra K. Chaturvedi,
  • Kishor K. Bhakat,
  • Angie Rizzino and
  • Sidharth Mahapatra

Medulloblastoma (MB) is the most common malignant central nervous system tumor in pediatric patients. Mainstay of therapy remains surgical resection followed by craniospinal radiation and chemotherapy, although limitations to this therapy are applied...

  • Article
  • Open Access
3 Citations
3,032 Views
16 Pages

Inconsistent Findings of Cardiac Troponin T and I in Clinical Routine Diagnostics: Factors of Influence

  • Abass Eidizadeh,
  • Laura Fraune,
  • Andreas Leha,
  • Rolf Wachter,
  • Abdul R. Asif and
  • Lutz Binder

16 July 2021

Cardiac troponins are crucial for the diagnosis of acute myocardial infarction. Despite known differences in their diagnostic implication, there are no recommendations for only one of the two troponins, cardiac troponin I (cTnI) and troponin T (cTnT)...

  • Review
  • Open Access
395 Views
42 Pages

Toward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors

  • Carol Yen,
  • John W. Epling,
  • Michelle Rockwell and
  • Monifa Vaughn-Cooke

Diagnostic errors have been a critical concern in healthcare, leading to substantial financial burdens and serious threats to patient safety. The Improving Diagnosis in Health Care report by the National Academies of Sciences, Engineering, and Medici...

  • Article
  • Open Access
1,584 Views
18 Pages

Health Professionals’ Preferences for Next-Generation Sequencing in the Diagnosis of Suspected Genetic Disorders in the Paediatric Population

  • Mario Cesare Nurchis,
  • Gerardo Altamura,
  • Gian Marco Raspolini,
  • Enrico Capobianco,
  • Luca Salmasi and
  • Gianfranco Damiani

10 January 2025

Background/Objectives: Next-generation sequencing (NGS) can explain how genetics influence morbidity and mortality in children. However, it is unclear whether health providers will perceive and use such treatments. We conducted a discrete choice expe...

  • Article
  • Open Access
13 Citations
4,086 Views
13 Pages

Background and objectives: Diagnostic delay causes unfavorable outcomes among cancer patients. It has been widely analyzed in solid tumors. However, data regarding hematological malignancies diagnostic delay are scarce. We aimed to evaluate diagnosti...

  • Article
  • Open Access
3 Citations
5,094 Views
11 Pages

Diagnostics in Patients Suspect for Breast Cancer in The Netherlands

  • Madelon M. Voets,
  • Catharina G. M. Groothuis-Oudshoorn,
  • Liset H. J. Veneklaas,
  • Srirang Manohar,
  • Mariël Brinkhuis,
  • Jeroen Veltman,
  • Linda de Munck,
  • Lioe-Fee de Geus-Oei,
  • Mireille J. M. Broeders and
  • Sabine Siesling

29 November 2021

The goal of this study was to describe the variation in hospital-based diagnostic care activities for patients with symptomatology suspect for breast cancer in The Netherlands. Two cohorts were included: the ‘benign’ cohort (30,334 women...

  • Article
  • Open Access
50 Citations
5,007 Views
9 Pages

20 February 2020

The European Working group on Sarcopenia in Older People recently updated the diagnostic criteria for sarcopenia. It is yet unclear how these modified criteria influence the rate of diagnosis in high risk populations, such as liver cirrhosis. We ther...

  • Article
  • Open Access
2 Citations
923 Views
21 Pages

20 May 2025

Optical diagnostic techniques represent an attractive complement to conventional pulp vitality tests, as they can provide direct information about the vascular status of the pulp. However, the complex, multi-layered structure of a tooth significantly...

  • Article
  • Open Access
22 Citations
3,512 Views
13 Pages

Non-Invasive Lung Cancer Diagnostics through Metabolites in Exhaled Breath: Influence of the Disease Variability and Comorbidities

  • Azamat Z. Temerdashev,
  • Elina M. Gashimova,
  • Vladimir A. Porkhanov,
  • Igor S. Polyakov,
  • Dmitry V. Perunov and
  • Ekaterina V. Dmitrieva

30 January 2023

Non-invasive, simple, and fast tests for lung cancer diagnostics are one of the urgent needs for clinical practice. The work describes the results of exhaled breath analysis of 112 lung cancer patients and 120 healthy individuals using gas chromatogr...

  • Feature Paper
  • Review
  • Open Access
309 Citations
59,792 Views
7 Pages

13 February 2017

The criteria for posttraumatic stress disorder PTSD have changed considerably with the newest edition of the American Psychiatric Association’s (APA) Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Changes to the diagnostic criteria fr...

  • Article
  • Open Access
5 Citations
8,152 Views
25 Pages

7S Model for Technology Protection of Organizations

  • Hyunae Park,
  • Youngcheon Yoo and
  • Hwansoo Lee

22 June 2021

Given the importance of technologies to organizations, technology leakages can cause considerable financial losses and threaten the survival of firms. Although organizations use technology protection diagnostic models to prevent such leakages, most d...

  • Article
  • Open Access
4 Citations
2,895 Views
13 Pages

Impact of Morphotype on Image Quality and Diagnostic Performance of Ultra-Low-Dose Chest CT

  • Anne-Claire Ortlieb,
  • Aissam Labani,
  • François Severac,
  • Mi-Young Jeung,
  • Catherine Roy and
  • Mickaël Ohana

26 July 2021

Objectives: The image quality of an Ultra-Low-Dose (ULD) chest CT depends on the patient’s morphotype. We hypothesize that there is a threshold beyond which the diagnostic performance of a ULD chest CT is too degraded. This work assesses the influenc...

  • Article
  • Open Access
2 Citations
1,861 Views
23 Pages

23 November 2023

In complex work domains, not all possible faults can be anticipated by designers or handled by automation. Humans therefore play an important role in fault diagnosis. To support their diagnostic reasoning, it is necessary to understand the requiremen...

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