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  • Systematic Review
  • Open Access
9 Citations
3,833 Views
13 Pages

Correlations between Dental Implant Infectious Pathologies and Maxillary Sinusitis: A Review Article

  • Simina Angela Lăcrimioara Iușan,
  • Carmen Costache,
  • Ondine Patricia Lucaciu,
  • Bianca-Nausica Petrescu and ,
  • Ioana Codruța Mirică,
  • Dan-Alexandru Toc and
  • Silviu Albu
  • + 2 authors+ 0 author

1 August 2023

(1) Background: The demands of patients for aesthetic and functional rehabilitation of edentulous areas led to the use of dental implants as therapeutic means on an increasingly large scale. This aspect determined the appearance of some infectious pa...

(This article belongs to the Special Issue Implant Dentistry—Trends, Challenges and Innovations)
  • Article
  • Open Access
1,046 Views
17 Pages

Assessment of Associations Between Sociodemographic and Analysis of Risk Factors for Oral Infectious Pathology in Patients Scheduled for Total Hip and Knee Arthroplasty

  • Dana Nicoleta Mihai,
  • Paul Dan Sîrbu,
  • Liliana Savin,
  • Norin Forna and ,
  • Claudiu Topoliceanu,
  • Cristina Dascălu and
  • Norina Consuela Forna
  • + 2 authors+ 0 author

24 November 2025

The aim of this study was to evaluate the factors associated with the occurrence of oral infection sources in patients scheduled for total hip or knee arthroplasty, with the purpose of establishing standardized preoperative dental triage criteria. Ma...

  • Article
  • Open Access
10 Citations
4,876 Views
19 Pages

A Comparative Study of Pathology and Host Immune Response Induced by Very Virulent Infectious Bursal Disease Virus in Experimentally Infected Chickens of Aseel and White Leghorn Breeds

  • Shyama N. Prabhu,
  • Ajay Pratap Singh,
  • Berin P. Varghese,
  • Kuldeep Dhama and ,
  • Shambhu Dayal Singh and
  • Rajendra Singh
  • + 1 author+ 0 author

26 October 2020

Indigenous breeds of young chickens in India are believed to be resistant to the classical strain of infectious bursal disease virus (IBDV). However, the mechanism underlying this resistance is obscure. Innate immunity is a key factor in defining the...

(This article belongs to the Section Pathogens-Host Immune Boundaries)
  • Article
  • Open Access
6 Citations
5,152 Views
12 Pages

Pathology and VP2-Based Characterization of Infectious Bursal Disease Virus Associated with an Outbreak in Layer Chickens in Ghana

  • Ben Enyetornye,
  • Henry A. Abugri,
  • Ama K. Kusi-Appiah,
  • Grazieli Maboni and ,
  • Theophilus Odoom,
  • Nicole L. Gottdenker and
  • Binu T. Velayudhan
  • + 2 authors+ 0 author

17 December 2024

Infectious bursal disease (IBD) continues to threaten poultry production globally, with highly virulent strains circulating in many parts of Africa. In this study, molecular characterization was performed on a circulating infectious bursal disease vi...

(This article belongs to the Section Epidemiology of Infectious Diseases)
  • Article
  • Open Access
17 Citations
5,774 Views
13 Pages

Development of a New Tomato Torrado Virus-Based Vector Tagged with GFP for Monitoring Virus Movement in Plants

  • Przemysław Wieczorek,
  • Marta Budziszewska,
  • Patryk Frąckowiak and
  • Aleksandra Obrępalska-Stęplowska

20 October 2020

Green fluorescent protein (GFP)-tagged viruses are basic research tools widely applied in studies concerning molecular determinants of disease during virus infection. Here, we described a new generation of genetically stable infectious clones of toma...

(This article belongs to the Special Issue Plant Virus Emergence)
  • Article
  • Open Access
7 Citations
5,787 Views
24 Pages

Main Causes of Death in Piglets from Different Brazilian Nursery Farms Based on Clinical, Microbiological, and Pathological Aspects

  • Jean Carlo Olivo Menegatt,
  • Fernanda Felicetti Perosa,
  • Anderson Hentz Gris,
  • Manoela Marchezan Piva and ,
  • Guilherme Carvalho Serena,
  • Diego Luiz Bordignon,
  • Carolina Reck,
  • Álvaro Menin,
  • Tatiane Terumi Negrão Watanabe and
  • David Driemeier
  • + 5 authors+ 0 author

11 December 2023

Necropsies can reveal herd problems or comorbidities that can lead to management corrections, improvements in animal performance, and better decision making. Furthermore, the pattern and causes of mortality might differ when different systems are eva...

(This article belongs to the Section Veterinary Clinical Studies)
  • Article
  • Open Access
8 Citations
4,612 Views
14 Pages

9 September 2020

Infectious keratoconjunctivitis (IKC) is a common transmissible ocular disease in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus). In large outbreaks, IKC may affect tens of animals in a herd, with the most severe cases often...

(This article belongs to the Special Issue Animal and Wildlife Viruses)
  • Systematic Review
  • Open Access
7 Citations
8,168 Views
12 Pages

21 March 2023

The main objective of this systematic review was to evaluate the microbiology of maxillary sinus infections and to determine whether an odontogenic origin of the infection can be established. The PIE question posed was the following: In patients with...

  • Article
  • Open Access
1 Citations
1,084 Views
13 Pages

Preventable Infectious Pathology Dominates Neonatal Readmissions: A Retrospective Analysis from a Pediatrics Department in Ploiești, Romania

  • Daniela-Eugenia Popescu,
  • Ioana Rosca,
  • Alina Turenschi,
  • Anca Miu and ,
  • Elena Poenaru,
  • Andreea Teodora Constantin,
  • Gabriel-Petre Gorecki and
  • Leonard Nastase
  • + 3 authors+ 0 author

26 February 2026

Background: Readmission of newborns within the first 28 days after initial discharge represents a significant healthcare concern, causing distress to families and financial burden on healthcare systems. Understanding readmission patterns and risk fac...

(This article belongs to the Section Pediatric Neonatology)
  • Article
  • Open Access
6 Citations
197 Views

More Specialties, Fewer Problems: Using Collaborative Competency Between Infectious Diseases, Podiatry, and Pathology to Improve the Care of Patients with Diabetic Foot Osteomyelitis

  • Vimal V. Jhaveri,
  • Christopher Sullivan,
  • Ashley Ward,
  • John M. Giurini and ,
  • Adolf W. Karchmer,
  • Isaac E. Stillman,
  • Roger B. Davis,
  • Jason A. Freed,
  • Mary T. LaSalvia and
  • Wendy Stead
  • + 5 authors+ 0 author

1 November 2022

Background: Diabetic foot osteomyelitis is a common infection where treatment involves multiple services, including infectious diseases, podiatry, and pathology. Despite its ubiquity in the hospital, consensus on much of its management is lacking. Me...

  • Article
  • Open Access
9 Citations
9,393 Views
15 Pages

1 October 2017

Staphylococcus aureus is a major pathogen causing osteomyelitis, amongst other diseases, and its methicillin-resistant form (MRSA) in particular poses a huge threat to public health. To increase our knowledge of the origin and evolution of S. aureus,...

(This article belongs to the Special Issue Ancient DNA)
  • Article
  • Open Access
7 Citations
4,929 Views
10 Pages

Mortality Causes in Free-Ranging Eurasian Brown Bears (Ursus arctos arctos) in Spain 1998–2018

  • Ana Balseiro,
  • Luis J. Royo,
  • Elena Gayo,
  • Ramón Balsera and ,
  • Olga Alarcia and
  • Juan F. García Marín
  • + 1 author+ 0 author

31 August 2020

This work summarizes the mortality cases of twenty-five free-ranging Eurasian wild brown bears (Ursus arctos arctos) from the Cantabrian mountain range submitted for necropsy in Asturias and Castilla y León (northwestern Spain) from 1998 to 20...

(This article belongs to the Special Issue Focus on Medicine, Surgery, Infectious and Parasitological Diseases, and Rehabilitation Aspects to Improve Wild Animal Health)
  • Editorial
  • Open Access
53 Citations
5,815 Views
4 Pages

Leptospira Infections in Domestic and Wild Animals

  • Giovanni Cilia,
  • Fabrizio Bertelloni and
  • Filippo Fratini

Leptospirosis is a worldwide-distributed, re-emerging zoonosis due to the large variety of wild and domestic animal species that can play the role of natural or accidental host. Currently, specific animal species play an important role as the reservo...

(This article belongs to the Special Issue Leptospira infections in Domestic and Wild Animal)
  • Article
  • Open Access
1 Citations
466 Views
22 Pages

Beyond Modified Transudates: Diagnostic Performance of the Feline Infectious Peritonitis Effusion Index on the Sysmex XN-1000V

  • Ricardo Lopes,
  • Filipe Sampaio,
  • Hugo Lima de Carvalho,
  • Cristina Costa Santos and ,
  • Melanie Ginder,
  • Cátia Fernandes,
  • Gonçalo Barros,
  • Luís Cardoso,
  • Elsa Leclerc Duarte and
  • Ana Cláudia Coelho
  • + 6 authors+ 1 author

2 October 2026

The antemortem clinical and clinicopathological diagnosis of feline infectious peritonitis (FIP) remains challenging, particularly when effusions deviate from the classically protein-rich, low-to-moderate-cellularity phenotype. The FIP Effusion Index...

(This article belongs to the Special Issue Molecular Epidemiology, Pathogenesis and Diagnosis of Animal Viral Diseases)
  • Article
  • Open Access
9 Citations
10,383 Views
25 Pages

Feline Infectious Peritonitis Effusion Index: A Novel Diagnostic Method and Validation of Flow Cytometry-Based Delta Total Nucleated Cells Analysis on the Sysmex XN-1000V®

  • Ricardo Lopes,
  • Filipe Sampaio,
  • Hugo Lima de Carvalho,
  • Andreia Garcês and ,
  • Cátia Fernandes,
  • Carolina Vitória Neves,
  • Alexandre Sardinha de Brito,
  • Tiago Marques,
  • Carlos Sousa and
  • Elsa Leclerc Duarte
  • + 9 authors+ 4 authors

13 November 2024

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led the medical and scientific community to explore the pathogenesis and clinical manifestations of coronaviruses. In felines, a widespread coronavirus known as feline...

(This article belongs to the Special Issue Advanced Therapy in Companion Animals)
  • Article
  • Open Access
6 Citations
3,319 Views
21 Pages

Investigations on the Health Status and Infection Risk of Harbour Seals (Phoca vitulina) from Waters of the Lower Saxon Wadden Sea, Germany

  • Ursula Siebert,
  • Jan Lakemeyer,
  • Martin Runge,
  • Peter Lienau and ,
  • Silke Braune,
  • Edda Bartelt,
  • Miguel L. Grilo and
  • Ralf Pund
  • + 3 authors+ 0 author

10 October 2024

Harbour seals (Phoca vitulina) are the most common pinniped species in the Wadden Sea of Schleswig-Holstein, Hamburg and Lower Saxony, Germany. Their numbers have recovered after significant depletion due to viral outbreaks and effects of anthropogen...

(This article belongs to the Special Issue Wildlife Diseases: Pathology and Diagnostic Investigation)
  • Review
  • Open Access
58 Citations
13,530 Views
45 Pages

Lipids in Pathophysiology and Development of the Membrane Lipid Therapy: New Bioactive Lipids

  • Manuel Torres,
  • Sebastià Parets,
  • Javier Fernández-Díaz,
  • Roberto Beteta-Göbel and ,
  • Raquel Rodríguez-Lorca,
  • Ramón Román,
  • Victoria Lladó,
  • Catalina A. Rosselló,
  • Paula Fernández-García and
  • Pablo V. Escribá
  • + 5 authors+ 0 author

24 November 2021

Membranes are mainly composed of a lipid bilayer and proteins, constituting a checkpoint for the entry and passage of signals and other molecules. Their composition can be modulated by diet, pathophysiological processes, and nutritional/pharmaceutica...

(This article belongs to the Section Biological Membrane Functions)
  • Feature Paper
  • Article
  • Open Access
106 Views
19 Pages

Wildlife Surveillance in North-Eastern Italy: Diagnostic Insights and Viral Detection in Gray Wolves and Golden Jackals

  • Mery Campalto,
  • Giammarco Assirelli,
  • Andrea Simonetto,
  • Elisa Mazzotta and ,
  • Arianna Brandimarti,
  • Marilena Carrino,
  • Francesca Crescenti,
  • Alda Natale,
  • Letizia Ceglie and
  • Nicola Pozzato
  • + 8 authors+ 3 authors

5 November 2026

Interfaces among humans, wildlife and domestic animals represent critical hotspots for the emergence and spread of infectious agents. The gray wolf (Canis lupus) and the golden jackal (Canis aureus) are expanding wild canid populations in Italy, whos...

(This article belongs to the Special Issue Wildlife Diseases: Pathology and Diagnostic Investigation—2nd Edition)
  • Article
  • Open Access
19 Citations
7,752 Views
21 Pages

Serologic, Virologic and Pathologic Features of Cats with Naturally Occurring Feline Infectious Peritonitis Enrolled in Antiviral Clinical Trials

  • Brian G. Murphy,
  • Diego Castillo,
  • N E Neely,
  • Amir Kol and ,
  • Terza Brostoff,
  • Chris K. Grant and
  • Krystle L. Reagan
  • + 2 authors+ 0 author

17 March 2024

Feline infectious peritonitis (FIP) is a multisystemic, generally lethal immuno-inflammatory disease of domestic cats caused by an infection with a genetic variant of feline coronavirus, referred to as the FIP virus (FIPV). We leveraged data from fou...

(This article belongs to the Section Viral Immunology, Vaccines, and Antivirals)
  • Article
  • Open Access
16 Views
13 Pages

11 November 2026

Background: Infectious bursal disease (IBD) remains a major challenge for poultry production, with very virulent IBD virus (vvIBDV) strains causing severe bursal damage, immunosuppression, and performance losses. This study evaluated the protective e...

(This article belongs to the Special Issue Poultry Vaccination and Vaccines)
  • Editorial
  • Open Access
7 Citations
3,071 Views
4 Pages

BK Virus and Transplantation

  • Carla Prezioso and
  • Valeria Pietropaolo

22 April 2021

As guest editors, we are pleased to present this Special Issue on BK virus (BKV) and transplantation with the intention of exploring some aspects related to BKV-associated diseases in transplant recipients, since they are still unclear [...]

(This article belongs to the Special Issue BK Virus and Transplantation)
  • Article
  • Open Access
282 Views
13 Pages

28 September 2026

Veterinary pathology laboratories play an important role in animal health, food security and disease surveillance by generating large volumes of diagnostic data. However routinely collected laboratory data is often underutilised as a source of epidem...

(This article belongs to the Section Veterinary Biomedical Sciences)
  • Review
  • Open Access
11 Citations
2,832 Views
8 Pages

Dental Pathologies of Endodontic Origin and Subsequent Bacterial Involvement—A Literature Review

  • Alexandru Gliga,
  • Mihai Săndulescu,
  • Oana Amza,
  • Ruxandra Stănescu and
  • Marina Imre

31 December 2023

Dental pathologies of endodontic origin are varied in nature, and include infectious and non-infectious causes. Through this review, we aim to provide a deeper understanding of the role of bacterial involvement and in the pathogenesis of endodontic p...

  • Article
  • Open Access
1 Citations
3,041 Views
13 Pages

The Challenges of The Diagnostic and Therapeutic Approach of Patients with Infectious Pathology in Emergency Medicine

  • Silvia Ioana Musuroi,
  • Adela Voinescu,
  • Corina Musuroi,
  • Luminita Mirela Baditoiu and ,
  • Delia Muntean,
  • Oana Izmendi,
  • Romanita Jumanca and
  • Monica Licker
  • + 3 authors+ 0 author

29 December 2023

The emergency department (ED) represents an important setting for addressing inappropriate antimicrobial prescribing practices because of the time constraints and the duration of microbiological diagnosis. The purpose of this study is to evaluate the...

(This article belongs to the Special Issue Emergency Medicine: Clinical Advances and Challenges in Diagnosis and Treatment)
  • Review
  • Open Access
6 Citations
1,766 Views
23 Pages

Hematological Parameters in Sheep: Variability, Determinants, and Applications in Flock Health Management

  • Vera Korelidou,
  • Panagiotis Simitzis,
  • Theofilos Massouras and
  • Athanasios I. Gelasakis

22 April 2026

Blood is a key component of organisms, serving numerous functions, including metabolism, innate and humoral responses, and hemostasis. Variations in hematological parameters can indicate the presence of infectious and non-infectious diseases, chronic...

(This article belongs to the Section Veterinary Clinical Studies)
  • Review
  • Open Access
22 Citations
6,033 Views
25 Pages

The Impact of Co-Infections for Human Gammaherpesvirus Infection and Associated Pathologies

  • Prishanta Chinna,
  • Katrin Bratl,
  • Humaira Lambarey,
  • Melissa J. Blumenthal and
  • Georgia Schäfer

22 August 2023

The two oncogenic human gammaherpesviruses Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV) cause significant disease burden, particularly in immunosuppressed individuals. Both viruses display latent and lytic phases of the...

(This article belongs to the Special Issue Host and Human Oncovirus Interaction)
  • Proceeding Paper
  • Open Access
4,147 Views
6 Pages

Development of Microcontroller-Based Automated Infectious Waste Segregation and Disinfection System: A COVID-19 Mitigation and Monitoring Response

  • Ralf D. Cuarto,
  • Adriel R. Baterna,
  • John Kenneth Q. Bulalacao,
  • Psalm Herald M. Cuajao and ,
  • Marc Theodore A. Casco,
  • Rolan Joseph T. Portento,
  • Charles G. Juarizo,
  • Thaddeo S. Garcia and
  • Rugi Vicente C. Rubi
  • + 4 authors+ 0 author

30 October 2023

With the recent increase in the amount of disposed infectious waste due to COVID-19, a growing interest to develop an efficient, economical, and effective infectious waste segregation system has prompted both the health sector and the government. Thi...

(This article belongs to the Proceedings of The 4th International Electronic Conference on Applied Sciences)
  • Article
  • Open Access
15 Citations
6,212 Views
19 Pages

The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging

  • Vittorio Pirani,
  • Paolo Pelliccioni,
  • Serena De Turris,
  • Alessandro Rosati and ,
  • Alessandro Franceschi,
  • Claudia Cesari,
  • Michele Nicolai and
  • Cesare Mariotti
  • + 3 authors+ 0 author

5 September 2019

Background: Syphilis, tuberculosis and toxoplasmosis are major infectious diseases worldwide; all of them are multisystem pathologies and share a possible ocular involvement. In this context, a fundamental help for the definitive diagnosis is provide...

(This article belongs to the Special Issue Application of Retinal and Optic Nerve Imaging in Clinical Medicine)
  • Article
  • Open Access
11 Citations
10,987 Views
15 Pages

The Characteristics of Herpes Simplex Virus Type 1 Infection in Rhesus Macaques and the Associated Pathological Features

  • Shengtao Fan,
  • Hongzhi Cai,
  • Xingli Xu,
  • Min Feng and ,
  • Lichun Wang,
  • Yun Liao,
  • Ying Zhang,
  • Zhanlong He,
  • Fengmei Yang and
  • Qihan Li
  • + 8 authors+ 3 authors

30 January 2017

As one of the major pathogens for human herpetic diseases, herpes simplex virus type 1 (HSV1) causes herpes labialis, genital herpes and herpetic encephalitis. Our aim here was to investigate the infectious process of HSV1 in rhesus macaques and the...

(This article belongs to the Section Animal Viruses)
  • Review
  • Open Access
7 Citations
5,818 Views
14 Pages

Amyloidoses are a group of diseases associated with the formation of pathological protein fibrils with cross-β structures. Approximately 5–10% of the cases of these diseases are determined by amyloidogenic mutations, as well as by transmission of inf...

(This article belongs to the Special Issue Pathological and Functional Amyloid Fibrils)
  • Case Report
  • Open Access
3 Citations
4,262 Views
9 Pages

Renal Abscess Associated with SGLT2 Inhibitors Administration in Heart Failure Without Other Previous Risk Factors: A Case Report

  • Madalina Andreea Munteanu,
  • Camelia Nicolae,
  • Razvan Ionut Popescu,
  • Andreea Rusescu and ,
  • Nicolae Paun and
  • Tiberiu Ioan Nanea
  • + 1 author+ 0 author

Background and Clinical Significance: Renal abscess represents one infectious urological complication with lethal potential. The treatment of this pathology may differ depending on the severity of the symptoms and the size of the infectious collectio...

(This article belongs to the Special Issue Cardiovascular Diseases: From Pathophysiology to Novel Therapeutic Approaches)
  • Review
  • Open Access
4 Citations
5,731 Views
20 Pages

Fundus Autofluorescence in Posterior and Panuveitis—An Under-Estimated Imaging Technique: A Review and Case Series

  • Matthias M. Mauschitz,
  • Markus Zeller,
  • Pradeep Sagar,
  • Suchitra Biswal and ,
  • Gabriela Guzman,
  • Jan H. Terheyden,
  • Carsten H. Meyer,
  • Frank G. Holz,
  • Carsten Heinz and
  • Maximilian W. M. Wintergerst
  • + 7 authors+ 2 authors

25 April 2024

Fundus autofluorescence (FAF) is a prompt and non-invasive imaging modality helpful in detecting pathological abnormalities within the retina and the choroid. This narrative review and case series provides an overview on the current application of FA...

(This article belongs to the Special Issue Molecular Pathology, Diagnostics and Therapeutics of Retinal Diseases)
  • Editorial
  • Open Access
8 Citations
4,577 Views
6 Pages

Genetic Evaluation of Prelingual Hearing Impairment: Recommendations of an European Network for Genetic Hearing Impairment

  • Laurence Jonard,
  • Davide Brotto,
  • Miguel A. Moreno-Pelayo,
  • Ignacio del Castillo and ,
  • Hannie Kremer,
  • Ronald Pennings,
  • Helena Caria,
  • Graça Fialho,
  • An Boudewyns and
  • Sandrine Marlin
  • + 28 authors+ 23 authors

The cause of childhood hearing impairment (excluding infectious pathology of the middle ear) can be extrinsic (embryofoetopathy, meningitis, trauma, drug ototoxicity, noise trauma, etc [...]

(This article belongs to the Special Issue Genetics of Hearing Loss—Volume II)
  • Article
  • Open Access
11 Citations
3,976 Views
12 Pages

Molecular Biology and Pathological Process of an Infectious Bronchitis Virus with Enteric Tropism in Commercial Broilers

  • Ana P. da Silva,
  • Ruediger Hauck,
  • Sabrina R. C. Nociti,
  • Colin Kern and ,
  • H. L. Shivaprasad,
  • Huaijun Zhou and
  • Rodrigo A. Gallardo
  • + 2 authors+ 0 author

28 July 2021

Infectious bronchitis virus (IBV) induces respiratory and urogenital disease in chickens. Although IBV replicates in the gastrointestinal tract, enteric lesions are uncommon. We have reported a case of runting-stunting syndrome in commercial broilers...

(This article belongs to the Special Issue Avian Respiratory Viruses, Volume II)
  • Article
  • Open Access
14 Citations
4,119 Views
18 Pages

Gut Microbiota as Early Predictor of Infectious Complications before Cardiac Surgery: A Prospective Pilot Study

  • Ekaterina Chernevskaya,
  • Evgenii Zuev,
  • Vera Odintsova,
  • Anastasiia Meglei and
  • Natalia Beloborodova

29 October 2021

Cardiac surgery remains a field of medicine with a high percentage of postoperative complications, including infectious ones. Modern data indicate a close relationship of infectious disorders with pathological changes in the composition of the gut mi...

(This article belongs to the Special Issue Targeting the Microbiome for Disease Diagnosis and Therapy: New Frontiers for Personalized Medicine)
  • Review
  • Open Access
3 Citations
6,750 Views
13 Pages

Gastrointestinal Ultrasound in Infectious Diseases: A Comprehensive Review

  • Francesca Aprile,
  • Marcello Vangeli,
  • Mariangela Allocca,
  • Alessandra Zilli and ,
  • Marjorie Costa Argollo,
  • Ferdinando D’amico,
  • Tommaso Lorenzo Parigi,
  • Silvio Danese and
  • Federica Furfaro
  • + 4 authors+ 0 author

27 August 2024

Infectious diseases affecting the gastrointestinal tract often present diagnostic challenges due to the variability in clinical manifestations and overlapping symptoms. Ultrasound imaging has emerged as a valuable tool in the assessment of gastrointe...

(This article belongs to the Section Gastroenterology & Hepatology)
  • Review
  • Open Access
42 Citations
7,198 Views
18 Pages

B Cells and Antibodies in Kawasaki Disease

  • Michael E. Lindquist and
  • Mark D. Hicar

The etiology of Kawasaki disease (KD), the leading cause of acquired heart disease in children, is currently unknown. Epidemiology supports a relationship of KD to an infectious disease. Several pathological mechanisms are being considered, including...

(This article belongs to the Special Issue Rare Diseases: Molecular Mechanisms and Therapeutic Strategies (II))
  • Review
  • Open Access
35 Citations
16,124 Views
26 Pages

A Review of Colonoscopy in Intestinal Diseases

  • Seung Min Hong and
  • Dong Hoon Baek

Since the development of the fiberoptic colonoscope in the late 1960s, colonoscopy has been a useful tool to diagnose and treat various intestinal diseases. This article reviews the clinical use of colonoscopy for various intestinal diseases based on...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Review
  • Open Access
62 Citations
7,245 Views
27 Pages

Innate Immunity Cells and the Neurovascular Unit

  • Ivan Presta,
  • Marco Flavio Michele Vismara,
  • Fabiana Novellino,
  • Annalidia Donato and ,
  • Paolo Zaffino,
  • Elisabetta Scali,
  • Krizia Caterina Pirrone,
  • Maria Francesca Spadea,
  • Natalia Malara and
  • Giuseppe Donato
  • + 5 authors+ 0 author

3 December 2018

Recent studies have clarified many still unknown aspects related to innate immunity and the blood-brain barrier relationship. They have also confirmed the close links between effector immune system cells, such as granulocytes, macrophages, microglia,...

(This article belongs to the Special Issue Macrophages in Inflammation)
  • Review
  • Open Access
10 Citations
7,459 Views
19 Pages

Construction of Infectious Clones of Begomoviruses: Strategies, Techniques and Applications

  • Mohd Faiz Mat Saad,
  • Aziz Ramlee Sau,
  • Muhamad Afiq Akbar,
  • Syarul Nataqain Baharum and ,
  • Ahmad Bazli Ramzi,
  • Noraini Talip and
  • Hamidun Bunawan
  • + 2 authors+ 0 author

29 June 2021

Begomovirus has become a potential threat to the agriculture sector. It causes significant losses to several economically important crops. Given this considerable loss, the development of tools to study viral genomes and function is needed. Infectiou...

(This article belongs to the Special Issue Plant-Microbe Interaction)
  • Hypothesis
  • Open Access
1 Citations
1,408 Views
23 Pages

Microvascular Genesis of Diseases: From Hypothesis to Theory

  • Ruslan A. Nasyrov,
  • Veronika A. Galichina,
  • Anna O. Drobintseva,
  • Daria V. Tonkonog and ,
  • Elena Yu. Kalinina and
  • Alexandra A. Agafonnikova
  • + 1 author+ 0 author

11 February 2026

Despite progress in understanding the molecular mechanisms of diseases, the dominant paradigm in explaining pathogenesis remains the concept of a pathogen’s direct damaging effect on parenchymal cells. Based on years of research, the authors of...

(This article belongs to the Section Physiology and Pathology)
  • Article
  • Open Access
2,519 Views
13 Pages

ANN-Based Discernment of Septic and Inflammatory Synovial Fluid: A Novel Method Using Viscosity Data from a QCR Sensor

  • Andrés Miranda-Martínez,
  • Berta Sufrate-Vergara,
  • Belén Fernández-Puntero,
  • María José Alcaide-Martin and ,
  • Antonio Buño-Soto and
  • José Javier Serrano-Olmedo
  • + 1 author+ 0 author

2 December 2022

The synovial fluid (SF) analysis involves a series of chemical and physical studies that allow opportune diagnosing of septic, inflammatory, non-inflammatory, and other pathologies in joints. Among the variety of analyses to be performed on the synov...

(This article belongs to the Special Issue Sensor Technologies for Human Health Monitoring)
  • Perspective
  • Open Access
5 Citations
3,157 Views
7 Pages

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder affecting millions worldwide. Emerging research has challenged the conventional notion of a direct correlation between amyloid deposition and neurodegeneration in AD. Recent s...

(This article belongs to the Special Issue Novel Hypotheses for Dementia and Neurodegenerative Diseases: From Molecular Mechanisms to Therapies)
  • Review
  • Open Access
44 Citations
15,807 Views
31 Pages

Prion Disease and the Innate Immune System

  • Barry M. Bradford and
  • Neil A. Mabbott

28 November 2012

Prion diseases or transmissible spongiform encephalopathies are a unique category of infectious protein-misfolding neurodegenerative disorders. Hypothesized to be caused by misfolding of the cellular prion protein these disorders possess an infectiou...

(This article belongs to the Special Issue Recent Developments in the Prion Field)
  • Editorial
  • Open Access
313 Views
4 Pages

6 September 2026

The World Health Organization has repeatedly issued warnings regarding the danger of an escalation in infectious pathology, whether through the appearance of new diseases termed emerging, or through re-emerging diseases resulting from increased morbi...

(This article belongs to the Special Issue Emerging Strategies in Infection Control and Antimicrobial Therapy)
  • Opinion
  • Open Access
4,873 Views
8 Pages

The Role of Chloroviruses as Possible Infectious Agents for Human Health: Putative Mechanisms of ATCV-1 Infection and Potential Routes of Transmission

  • Yury V. Zhernov,
  • Sonya O. Vysochanskaya,
  • Artem A. Basov,
  • Vitaly A. Sukhov and ,
  • Anton A. Simanovsky,
  • Inna A. Fadeeva,
  • Roman V. Polibin,
  • Ekaterina A. Sidorova,
  • Denis V. Shcherbakov and
  • Oleg V. Mitrokhin
  • + 5 authors+ 0 author

The Chlorovirus genus of the Phycodnaviridae family includes large viruses with a double-stranded DNA genome. Chloroviruses are widely distributed in freshwater bodies around the world and have been isolated from freshwater sources in Europe, Asia, A...

  • Article
  • Open Access
1 Citations
948 Views
16 Pages

Invariant and Diverse NKT Cells Regulate Bacterial Clearance and Pathology in Chlamydial Genital Tract Infection in Mice

  • Kazunari Ishii,
  • Toshinori Soejima,
  • Yoshiki Ohnishi,
  • Ryo Ozuru and ,
  • Ryota Itoh,
  • Bin Chou,
  • Michinobu Yoshimura,
  • Akinori Shimizu,
  • Yusuke Kurihara and
  • Kenji Hiromatsu
  • + 6 authors+ 1 author

15 November 2025

Chlamydia trachomatis infection causes pelvic inflammatory disease and infertility, but how host immune factors control pathogen clearance or pathology is not fully understood. Using a mouse model of genital tract infection with Chlamydia muridarum,...

(This article belongs to the Section Bacterial Pathogens)
  • Case Report
  • Open Access
1,474 Views
11 Pages

8 April 2026

Poultry disease outbreaks are frequently multifactorial, involving complex interactions between infectious agents and environmental stressors. This report describes a case of avian influenza (AI) co-infection in a commercial broiler farm located in M...

(This article belongs to the Special Issue Pathogenesis and Immune Responses of Viral Infections in Poultry and Wild Birds)

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