94 Results Found

It is crucial to improve poorly water-soluble orally administered drugs through both preclinical and therapeutic drug discovery. A co-amorphous formulation consisting of two low molecular weight (MW) molecules offers a solubility/dissolubility advant...

This paper reports the results of a study on the significance of the inertization system configuration of a laboratory-scale fixed bed batch reactor with regard to the yield of pyrolysis oil and reactor conversion. Two typical reactor inertization sy...

Particle adsorbents have gained significant traction in flue gas desulfurization applications, primarily attributed to their high structural homogeneity and large specific surface area. To address the multifaceted requirements of industrial sectors r...

A new cryochemical strategy of producing nanoparticles and polymorphous nanostructures of drugs is used, which is based on the dynamic combination of high and low temperatures, gas and solid phases, and inert carrier gases. This technology is applied...

It is well established that currently available inhaled drug formulations are associated with extremely low lung deposition. Currently available technologies alleviate this low deposition problem via mixing the drug with inert larger particles, such...

The perspective catalysts usable for the fabrication of thermocatalytic gas sensors were studied. The analysis of CO oxidation kinetics by Pd decorated Al2O3, ZSM-5, SnO2, CeO2/ZrO2 and some other carriers of catalysts showed that the application of...

Nanostructured Indium(III) oxide (In2O3) films deposited by low temperature pulsed electron deposition (LPED) technique on customized alumina printed circuit boards have been manufactured and characterized as gas sensing devices. Their electrical pro...

Silica nanoparticles (SiNPs) are generally regarded as safe and may represent an attractive carrier platform for nanomedical applications when loaded with biopharmaceuticals. Surface functionalization by different chemistries may help to optimize pro...

Micro- and nano-carrier formulations have been developed as drug delivery systems for active pharmaceutical ingredients (APIs) that suffer from poor physico-chemical, pharmacokinetic, and pharmacodynamic properties. Encapsulating the APIs in such sys...

Enzymes are used extensively as industrial bio-catalysts in various manufacturing and processing sectors. However, commercial enzymes are expensive in part due to the high cost of the nutrient medium for the biomass culture. Activated sludge (AS) is...

Immobilization of the recombinant, plant-derived Petroselinum crispum phenylalanine ammonia lyase (PcPAL) in electrospun matrices have the potential to create promising, easy-to-use biocatalysts. Polylactic acid (PLA) a biologically inert, commercial...

Amorphous silica as a food additive (E 551) is used in food materials (e.g., sweeteners, dairy products) for its anti-caking properties. The physicochemical properties of SiO2 also make it suitable to serve as a carrier of active substances in functi...

Enzyme immobilisation is a common strategy to increase enzymes resistance and reusability in a variety of excellent ‘green’ applications. However, the interaction with the solid support often leads to diminished specific activity, especially when non...

Dextran aldehyde (dexOx), resulting from the periodate oxidative cleavage of 1,2-diol moiety inside dextran, is a polymer that is very useful in many areas, including as a macromolecular carrier for drug delivery and other biomedical applications. In...

Late-stage modification of drug molecules is a fast method to introduce diversity into the already biologically active scaffold. A notable number of analogs of mefloquine, chloroquine, and hydroxychloroquine have been synthesized, starting from the r...

Bacterial biohybrid microswimmers aim at exploiting the inherent motion capabilities of bacteria (carriers) to transport objects (cargoes) at the microscale. One of the most desired properties of microswimmers is their ability to communicate with the...

One “Quality by Design” approach is the focus on the variability of the properties of the active substance. This is crucially important for active substances that are obtained from natural resources such as herbal plant material and extracts. In this...

Microbial pesticides can be significantly improved by adjuvants. At present, microbial pesticide formulations are mainly wettable powders and suspension concentrations, which are usually produced with adjuvants such as surfactants, carriers, protecti...

Green hydrogen is central to the energy transition, but its production often requires expensive materials and poses environmental risks due to the perfluorinated substances used in electrolysis. This study introduces a transformative approach to gree...

We report on the manufacture of a state-of-the-art heterogeneous non-noble metal catalyst, which is based on a molecularly well-defined phosphine-tagged cobalt corrole complex. This precursor compound is readily synthesized from convenient starting m...

Transmetalation, the exchange of metal ions between coordination complexes and biomolecules, has emerged as a powerful design lever in cancer metallopharmacology. Using thiosemicarbazones (TSCs) as a unifying case study, we show how redox-inert carri...

Emerging trends like the Internet of Things require an increasing number of different sensors, actuators and electronic devices. To enable new applications, such as wearables and electronic skins, flexible sensor technologies are required. However, e...

B chromosomes (Bs) are highly polymorphic additional chromosomes in the genomes of many species. Due to the dispensability of Bs and the lack of noticeable phenotypic effects in their carriers, they were considered genetically inert for a long time....

The objective of the research was to prepare Mn-based materials for use as oxygen carriers and investigate their reactivity in terms of their applicability to energy systems. The family of Fe2O3-MnO2 with the addition of TiO2 was prepared by mechanic...

DNA–nanoparticle conjugates have extraordinary optical and catalytic properties that have attracted great interest in biosensing and biomedical applications. Combining these special qualities has made it possible to create extremely sensitive a...

Silicon carbide is a wide-bandgap semiconductor useful in a new class of power devices in the emerging area of high-temperature and high-voltage electronics. The diffusion of SiC devices is strictly related to the growth of high-quality substrates an...

Following the fast development of microfluidics over the last decade, the need for methods for mixing two gases in flow at an overall flow rate ranging from 1 to 100 NmL·min−1 with programmable mixing ratios has been quickly increasing i...

During the last decade, the demand for natural gas has steadily increased for the prevention of environmental pollution. For this reason, many liquefied natural gas (LNG) carriers have been manufactured. Since one of the most important issues in the...

Oxygen carrier aided combustion (OCAC) is utilized to promote the combustion of relatively stable fuels already in the dense bed of bubbling fluidized beds by adding a new mechanism of fuel conversion, i.e., direct gas–solid reaction between th...

The microencapsulation of α-tocopherol based on the complex coacervation of low-molecular-weight chitosan (LMWC) and sodium lauryl ether sulphate (SLES) without harmful crosslinkers can provide biocompatible carriers that protect it from photod...

The implementation of nanotechnology in pulmonary delivery systems might result in better and more specific therapy. Therefore, a nano-sized drug carrier should be toxicologically inert and not induce adverse effects. We aimed to investigate the resp...

Uptake of particles by cells involves various natural mechanisms that are essential for their biological functions. The same mechanisms are used in the engulfment of synthetic colloidal drug carriers, while the extent of the uptake affects the biolog...

Modern pharmaceutics requires novel drug loading platforms with high drug loading capacity, controlled release, high stability, and good biocompacity. Metal–organic frameworks (MOFs) show promising applications in biomedicine owing to their ext...

The chemical looping gasification of residual biomasses—operated in fluidized beds composed of oxygen-carriers—may allow the production of biofuels from syngas. This biomass-to-fuel chain can contribute to mitigate climate change, avoidin...

Chemical looping gasification (CLG) is a novel gasification technique, allowing for the production of a nitrogen-free high calorific synthesis gas from solid hydrocarbon feedstocks, without requiring a costly air separation unit. Initial advances to...

Graphene in its pristine form has demonstrated a gas detection ability in an inert carrier gas. For practical use in ambient atmosphere, its sensor properties should be enhanced with functionalisation by defects and dopants, or by decoration with nan...

In recent years, cadmium sulfide (CdS) has been widely investigated due to its excellent photocatalytic performance. However, its practical application in pollutant treatment is limited by its narrow photoresponse range and susceptibility to photocor...

The process of slow pyrolysis of seven nut shell samples, in a nitrogen-purged atmosphere, has been studied, as well as characteristics of biochar obtained. The heat carrier with a temperature of 400–600 °C (with a step of 100 °C) was s...

The use of the Laser Metal Deposition (LMD) technology as a manufacturing and repairing technique in industrial sectors like the die and mold and aerospace is increasing within the last decades. Research carried out in the field of LMD process situat...

Photodynamic inactivation (PDI) is a process that uses photosensitizing substances to produce reactive oxygen species. This is achieved by exposing photosensitizers to specific wavelengths of light and causing oxidative damage in cells. This steriliz...

Polysaccharides, oligosaccharides, and their derivatives, particularly of amylose, cellulose, chitosan, and β-cyclodextrin, are well-known chiral selectors (CSs) of chiral stationary phases (CSPs) in chromatography, because they can separate a wide r...

Carbon gels are a kind of porous organic polymer, which play pivotal roles in electrode, supercapacitor, hydrogen storage, and catalysis. Carbon gels are commonly prepared by the condensation of resorcinol and formaldehyde. The as-prepared polymers a...

Although titanium dioxide gathers many of the required properties for its application in photocatalytic processes, its lack of activity in the visible range is a major hurdle yet to be overcome. Among different strategies, the post-synthesis modifica...

Tar is an unavoidable biomass gasification byproduct. Tar formation reduces gasification efficiency and limits the further application of biomass gasification technology. Hence, efficient tar removal is a major problem to be solved in the formation a...

Binder materials are needed to keep particles of active masses in electrodes for batteries and supercapacitors together and to ensure their adherence to the current collector. Mostly synthetic polymeric materials are used. Because they are electroche...

The photocatalytic CO2 reduction (PCR) into value-added fuels offers a promising solution to energy shortages and the greenhouse effect, thanks to the mild conditions and environmental sustainability. However, the activation of CO2 is challenging bec...

A series of biocide-containing polyethylene composites were obtained using novel guanidine-containing copolymers immobilized on an inert mineral carrier. Multispecies microbial communities were isolated from the surface of polyethylene samples either...

Silicon quantum dots (Si-QDs) have great potential for biomedical applications, including their use as biological fluorescent markers and carriers for drug delivery systems. Biologically inert Si-QDs are less toxic than conventional cadmium-based QDs...

In this study, dextran-based hydrogels were synthesized in dimethyl sulfoxide via free-radical polymerization with three structurally different crosslinking agents: divinyl benzene (DVB), diethylene glycol diacrylate (DEGDA), and 4,4′-di(methac...

Cyclodextrins, representing a versatile family of cyclic oligosaccharides, have extensive pharmaceutical applications due to their unique truncated cone-shaped structure with a hydrophilic outer surface and a hydrophobic cavity, which enables them to...