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  • Review
  • Open Access
1 Citations
3,020 Views
23 Pages

Frozen Foods: A Comprehensive Review of Technologies, Challenges, and Future Prospects

  • Hongjuan Teng,
  • Yuejiao Xing,
  • Yue San,
  • Li Zheng,
  • Zhongjiang Wang and
  • Bailiang Li

24 May 2026

Freezing effectively extends the shelf life of food and maintains product quality by inhibiting microorganisms, enzyme activity, and chemical reactions. However, issues such as ice crystal formation, protein denaturation, lipid oxidation, and the low...

(This article belongs to the Section Food Process Engineering)
  • Article
  • Open Access
2 Citations
1,533 Views
28 Pages

4 September 2025

Ice nucleation temperatures and associated ice growth rates are critical parameters in defining the initial ice morphology template, which governs dry layer resistance during sublimation and therefore impacts primary drying kinetics and overall proce...

(This article belongs to the Topic Broadband Dielectric Spectroscopy Fundamentals and Applications)
  • Article
  • Open Access
34 Citations
4,536 Views
14 Pages

8 November 2018

The modifiers NTC (nano-TiO2/CaCO3) and BF (basalt fiber) were adopted to modify a base matrix asphalt mixture. The base matrix asphalt mixture and three kinds of modified asphalt mixture under F–T (freeze–thaw) cycles were scanned by com...

(This article belongs to the Special Issue Asphalt Materials)
  • Article
  • Open Access
9 Citations
5,405 Views
14 Pages

11 May 2019

The freeze-drying process removes water from a product through freezing, sublimation and desorption procedures. However, the extreme conditions of the freeze-drying environment, such as the limited space, vacuum and freezing temperatures of as much a...

(This article belongs to the Special Issue Advanced Sensors for Real-Time Monitoring Applications)
  • Article
  • Open Access
10 Citations
3,000 Views
18 Pages

23 March 2023

In high-altitude and cold regions, external dynamic geological processes, such as glacial melting and other processes are intense, which frequently results in surface dynamic geological processes, such as slope collapse, landslides, debris flows, and...

  • Article
  • Open Access
2 Citations
4,024 Views
12 Pages

Investigation of the Foam Development Stages by Non-Destructive Testing Technology Using the Freeze Foaming Process

  • Johanna Maier,
  • Thomas Behnisch,
  • Vinzenz Geske,
  • Matthias Ahlhelm,
  • David Werner,
  • Tassilo Moritz,
  • Alexander Michaelis and
  • Maik Gude

6 December 2018

With a novel Freeze Foaming method, it is possible to manufacture porous cellular components whose structure and composition also enables them for application as artificial bones, among others. To tune the foam properties to our needs, we have to und...

(This article belongs to the Special Issue In-Situ X-Ray Tomographic Study of Materials)
  • Article
  • Open Access
9 Citations
4,741 Views
20 Pages

7 February 2025

In the pharmaceutical industry, freeze-drying is crucial for the stability of active pharmaceutical ingredients (APIs). Monitoring this complex process presents challenges as traditional methods often lack real-time insights, potentially leading to q...

(This article belongs to the Section Pharmaceutical Processes)
  • Article
  • Open Access
2 Citations
887 Views
20 Pages

Impact Dynamics and Freezing Performance of Porcine Bile Droplets on Horizontal Cold Substrates: Towards Advanced and Sustainable Food Processing

  • Xinkang Hu,
  • Bo Zhang,
  • Libang Chen,
  • Zhenpeng Zhang,
  • Huanhuan Zhang,
  • Xintong Du,
  • Xu Wang,
  • Lulu Zhang,
  • Tao Yang and
  • Chundu Wu

21 June 2025

With the development of the agro-processing industry, the efficient cryogenic treatment and resource utilization of porcine bile—a high-value byproduct—has received increasing attention. This study investigates the dynamic behaviour and f...

(This article belongs to the Special Issue Development of Green and Advanced Food Freezing/Anti-Freezing Technologies)
  • Review
  • Open Access
2,405 Views
14 Pages

30 September 2025

Background/Objectives: Recently, new methods of monitoring sublimation flow during freeze-drying operations have been proposed. They are based either on measuring the difference between the temperature of the heat transfer liquid at the inlet and out...

(This article belongs to the Special Issue Drug Products: Latest Trends in Technical Development and Manufacturing of Parenteral Products)
  • Article
  • Open Access
9 Citations
3,133 Views
16 Pages

Models for ice sublimation from a freeze-drying vial rely on the assumption of a planar ice interface up to ~25% loss of ice mass (which is difficult to qualify) whereas single-vial determinations of the sublimation endpoint (by temperature sensors)...

(This article belongs to the Special Issue New Trends in Freeze-Drying of Pharmaceutical Products)
  • Review
  • Open Access
3 Citations
3,244 Views
14 Pages

Spray Freezing Coating on the Carrier Particles for Powder Preparation

  • Qing Xu,
  • Ruixin Wang,
  • Fan Zhang,
  • Ruifang Wang,
  • Long Wu and
  • Bo Lin

24 June 2022

Carrier particle spray freeze-drying is a new technology with high added value for thermosensitive powder spray freeze-drying. The technology includes the following steps: atomization, coating, freezing, and drying. Due to the action of carrier parti...

(This article belongs to the Section Surface Characterization, Deposition and Modification)
  • Article
  • Open Access
6 Citations
6,669 Views
18 Pages

Novel Real-Time Diagnosis of the Freezing Process Using an Ultrasonic Transducer

  • Yen-Hsiang Tseng,
  • Chin-Chi Cheng,
  • Hong-Ping Cheng and
  • Dasheng Lee

4 May 2015

The freezing stage governs several critical parameters of the freeze drying process and the quality of the resulting lyophilized products. This paper presents an integrated ultrasonic transducer (UT) in a stainless steel bottle and its application to...

(This article belongs to the Section Physical Sensors)
  • Article
  • Open Access
12 Citations
4,271 Views
20 Pages

The measurement of product temperature is one of the methods that can be adopted, especially in the pharmaceutical industry, to monitor the freeze-drying process and to obtain the values of the process parameters required by mathematical models usefu...

(This article belongs to the Special Issue Advance in Pharmaceutical Engineering: PAT and Model-Based Approach for QbD and Continuous Processes)
  • Article
  • Open Access
8 Citations
3,511 Views
16 Pages

Application of CO2-Laser Micro-Perforation Technology to Freeze-Drying Whole Strawberry (Fragaria ananassa Duch.): Effect on Primary Drying Time and Fruit Quality

  • Marlene Pinto,
  • Cynthia Kusch,
  • Karyn Belmonte,
  • Silvana Valdivia,
  • Pedro Valencia,
  • Cristian Ramírez and
  • Sergio Almonacid

9 May 2024

Freeze-drying (FD) processing preserves foods by combining the most effective traditional technologies. FD conserves the structure, shape, freshness, nutritional/bioactive value, color, and aroma at levels similar to or better than those of refrigera...

(This article belongs to the Section Food Engineering and Technology)
  • Review
  • Open Access
49 Citations
12,022 Views
23 Pages

Finite Element Method for Freezing and Thawing Industrial Food Processes

  • Tobi Fadiji,
  • Seyed-Hassan Miraei Ashtiani,
  • Daniel I. Onwude,
  • Zhiguo Li and
  • Umezuruike Linus Opara

16 April 2021

Freezing is a well-established preservation method used to maintain the freshness of perishable food products during storage, transportation and retail distribution; however, food freezing is a complex process involving simultaneous heat and mass tra...

(This article belongs to the Section Food Packaging and Preservation)
  • Review
  • Open Access
13 Citations
9,642 Views
39 Pages

20 November 2024

As global demand for freshwater grows, seawater desalination has become one of the most promising methods for obtaining freshwater. Many coastal nations have included it in their sustainable development plans and are actively advancing related techno...

(This article belongs to the Section Sustainable Engineering and Science)
  • Review
  • Open Access
85 Citations
18,949 Views
20 Pages

Crystallization Behavior and Quality of Frozen Meat

  • David S. Dang,
  • Luis J. Bastarrachea,
  • Silvana Martini and
  • Sulaiman K. Matarneh

5 November 2021

Preservation of meat through freezing entails the use of low temperatures to extend a product’s shelf-life, mainly by reducing the rate of microbial spoilage and deterioration reactions. Characteristics of meat that are important to be preserve inclu...

(This article belongs to the Section Meat)
  • Article
  • Open Access
5 Citations
3,046 Views
9 Pages

25 September 2020

Forest owners will be able to solve the problem of protecting small forest seeds from mechanical and atmospheric influences during aerial sowing, as well as the problem of manufacturing capsules in the field, saving financial, time and material resou...

(This article belongs to the Section Inventions and Innovation in Biotechnology and Materials)
  • Review
  • Open Access
426 Citations
53,185 Views
22 Pages

Freeze-Drying of Plant-Based Foods

  • Sagar Bhatta,
  • Tatjana Stevanovic Janezic and
  • Cristina Ratti

13 January 2020

Vacuum freeze-drying of biological materials is one of the best methods of water removal, with final products of highest quality. The solid state of water during freeze-drying protects the primary structure and the shape of the products with minimal...

(This article belongs to the Special Issue Freeze-Drying Technology in Foods)
  • Review
  • Open Access
80 Citations
15,087 Views
27 Pages

29 November 2023

Drying is the main technical means of fruit and vegetable processing and storage; freeze drying is one of the best dehydration processes for fruit and vegetables, and the quality of the final product obtained is the highest. The process is carried ou...

(This article belongs to the Section Food Engineering and Technology)
  • Review
  • Open Access
15 Citations
8,698 Views
39 Pages

This article provides an overview on manufacturing composite carbon nanofiber-based aerogels through freeze casting technology. As known, freeze casting is a relatively new manufacturing technique for generating highly porous structures. During the p...

(This article belongs to the Section Fiber Composites)
  • Article
  • Open Access
13 Citations
4,738 Views
16 Pages

A NIR-Based Study of Desorption Kinetics during Continuous Spin Freeze-Drying

  • Laurens Leys,
  • Gust Nuytten,
  • Joris Lammens,
  • Pieter-Jan Van Bockstal,
  • Jos Corver,
  • Chris Vervaet and
  • Thomas De Beer

The pharmaceutical industry is progressing toward the development of more continuous manufacturing techniques. At the same time, the industry is striving toward more process understanding and improved process control, which requires the implementatio...

(This article belongs to the Special Issue New Trends in Freeze-Drying of Pharmaceutical Products)
  • Article
  • Open Access
33 Citations
4,274 Views
15 Pages

11 August 2022

The aim of this study was to investigate the effect of application of pulsed electric field (PEF) and different freezing methods (fast, slow and vacuum freezing) on the drying kinetics as well as selected physical properties of freeze-dried apple. Th...

(This article belongs to the Special Issue Novel Processing Technology for Shelf Life Extension in Food)
  • Article
  • Open Access
12 Citations
10,290 Views
17 Pages

Mangosteen Pericarp Processing Technology to Create Economic Value and Reduce Biowaste

  • Alisa Soontornwat,
  • Thadchapong Pongsuttiyakorn,
  • Samak Rakmae,
  • Eakasit Sritham,
  • Panmanas Sirisomboon,
  • Umed Kumar Pun,
  • Warawut Krusong and
  • Pimpen Pornchaloempong

20 July 2024

This research comparatively investigates different mangosteen pericarp processing schemes. The experimental pericarp processing schemes were hot air drying (HAD; control), quick freezing/HAD (QF + HAD), slow freezing/HAD (SF + HAD), and slow freezing...

(This article belongs to the Section Food Security and Sustainability)
  • Opinion
  • Open Access
5 Citations
4,275 Views
5 Pages

Could ‘Isochoric Freezing’ Revolutionise Food Preservation?

  • Kostadin Fikiin,
  • Stepan Akterian,
  • Alain Le Bail,
  • James K. Carson and
  • Trygve M. Eikevik

4 June 2024

The present article responds to the food engineering community’s growing interest in an emerging and lauded approach to food preservation, popularised by its developers as ‘isochoric freezing’. A strong campaign in the scientific li...

(This article belongs to the Topic Sustainable Food Processing)
  • Article
  • Open Access
26 Citations
13,152 Views
27 Pages

5 May 2023

Lyophilization is a widely used preservation method for thermosensitive products. It consists of three process steps: freezing, primary and secondary drying. One of the major drawbacks is the long processing time. The main optimization effort was put...

(This article belongs to the Special Issue Features, Reviews and Perspectives for the 10th Anniversary of Processes)
  • Article
  • Open Access
25 Citations
3,204 Views
20 Pages

28 October 2021

The aim of this study was to reveal the macroscopic and mesoscopic deterioration behaviors of concrete under the coupling effect of chlorine salt erosion and the freezing–thawing cycle. The rapid freezing–thawing test was carried out in a 5% chlorine...

  • Article
  • Open Access
50 Citations
9,546 Views
15 Pages

Energy and Quality Aspects of Freeze-Drying Preceded by Traditional and Novel Pre-Treatment Methods as Exemplified by Red Bell Pepper

  • Katarzyna Rybak,
  • Oleksii Parniakov,
  • Katarzyna Samborska,
  • Artur Wiktor,
  • Dorota Witrowa-Rajchert and
  • Małgorzata Nowacka

13 February 2021

Freeze-drying is one of the most expensive and most energy intensive processes applied in food technology. Therefore, there have been significant efforts to reduce the freeze-drying time and decrease its energy consumption. The aim of this work was t...

(This article belongs to the Special Issue Innovative Food Science and Sustainable Process Management)
  • Article
  • Open Access
604 Views
20 Pages

Study on Temperature Response Characteristics of Gas Containing Coal at Different Freezing Temperatures

  • Qiang Wu,
  • Zhaofeng Wang,
  • Liguo Wang,
  • Shujun Ma,
  • Yongxin Sun,
  • Shijie Li and
  • Boyu Lin

19 February 2026

In the process of using the freezing method to uncover coal from stone gates, the thermal evolution profiles of the coal body during the freezing process tend to be complex due to the presence of gas and moisture. To investigate the temperature respo...

  • Article
  • Open Access
6 Citations
4,937 Views
15 Pages

18 November 2024

Seafood preservation techniques have evolved from ancient methods to modern innovations like canning, freezing, and surimi production. Canning in the 19th century introduced airtight containers, while commercial freezing technologies like flash freez...

(This article belongs to the Special Issue Innovation, Productivity and Economic Growth: New Insights)
  • Article
  • Open Access
99 Citations
15,751 Views
17 Pages

Economic Analysis of a Freeze-Drying Cycle

  • Lorenzo Stratta,
  • Luigi C. Capozzi,
  • Simone Franzino and
  • Roberto Pisano

2 November 2020

Freeze-drying has always been considered an extremely expensive procedure to dehydrate food or pharmaceutical products, and for this reason, it has been employed only if strictly necessary or when the high added value of the final product could justi...

(This article belongs to the Special Issue Modern Freeze Drying Design for More Efficient Processes)
  • Article
  • Open Access
9 Citations
2,715 Views
16 Pages

Study on Microwave Freeze-Drying of Krill

  • Hao-Cheng Chang and
  • Su-Der Chen

30 June 2024

Antarctic krill (Euphausua superba) need to undergo freeze-drying to facilitate lipid extraction, but freeze-drying is time-consuming and energy-intensive, resulting in high processing costs. Microwave heating technology can reduce freeze-drying time...

(This article belongs to the Special Issue Advanced Drying Technologies in Food Processing)
  • Article
  • Open Access
40 Citations
5,389 Views
14 Pages

Freeze–Thaw Damage Characteristics of Concrete Based on Compressive Mechanical Properties and Acoustic Parameters

  • Dongye Lv,
  • Hanbing Liu,
  • Feng He,
  • Wensheng Wang,
  • Qiang Miao,
  • Hanjun Li,
  • Fuen Wang,
  • Jing Zhao and
  • Chengwei Shi

22 February 2024

Concrete is a versatile material widely used in modern construction. However, concrete is also subject to freeze–thaw damage, which can significantly reduce its mechanical properties and lead to premature failure. Therefore, the objective of th...

(This article belongs to the Section Advanced Composites)
  • Article
  • Open Access
53 Citations
7,863 Views
20 Pages

The Quality of Red Bell Pepper Subjected to Freeze-Drying Preceded by Traditional and Novel Pretreatment

  • Katarzyna Rybak,
  • Artur Wiktor,
  • Dorota Witrowa-Rajchert,
  • Oleksii Parniakov and
  • Małgorzata Nowacka

22 January 2021

It has been demonstrated previously in the literature that utilization of PEF or a combination of a pulsed electric field (PEF) and ultrasounds (US) can facilitate dehydration processes and improve the quality of dried products even better than the a...

(This article belongs to the Section Food Engineering and Technology)
  • Article
  • Open Access
26 Citations
4,504 Views
16 Pages

Spin Freezing and Its Impact on Pore Size, Tortuosity and Solid State

  • Joris Lammens,
  • Niloofar Moazami Goudarzi,
  • Laurens Leys,
  • Gust Nuytten,
  • Pieter-Jan Van Bockstal,
  • Chris Vervaet,
  • Matthieu N. Boone and
  • Thomas De Beer

Spin freeze-drying, as a part of a continuous freeze-drying technology, is associated with a much higher drying rate and a higher level of process control in comparison with batch freeze-drying. However, the impact of the spin freezing rate on the dr...

(This article belongs to the Special Issue New Trends in Freeze-Drying of Pharmaceutical Products)
  • Review
  • Open Access
41 Citations
7,333 Views
22 Pages

Progress on Thin Film Freezing Technology for Dry Powder Inhalation Formulations

  • Sagar R. Pardeshi,
  • Eknath B. Kole,
  • Harshad S. Kapare,
  • Sachin M. Chandankar,
  • Prashant J. Shinde,
  • Ganesh S. Boisa,
  • Sanjana S. Salgaonkar,
  • Prabhanjan S. Giram,
  • Mahesh P. More and
  • Vijayabhaskarreddy Junnuthula
  • + 3 authors

The surface drying process is an important technology in the pharmaceutical, biomedical, and food industries. The final stage of formulation development (i.e., the drying process) faces several challenges, and overall mastering depends on the end ste...

(This article belongs to the Special Issue Dry Powders for Pulmonary Delivery: Device and Formulation Technologies for an Enhanced Lung Deposition)
  • Review
  • Open Access
1,482 Views
22 Pages

12 June 2026

Persistent microplastics contaminate wastewater systems and pose significant environmental and human health risks due to their small size, buoyancy, persistence, and diverse physicochemical properties, which reduce the effectiveness of conventional t...

(This article belongs to the Section Industrial Crystallization)
  • Article
  • Open Access
2,026 Views
25 Pages

Pore-Scale Formation Characteristics of Impermeable Frozen Walls for Shallow Groundwater Contamination Remediation

  • Yunfeng Zhang,
  • Zhiqiang Zhao,
  • Guantao Ding,
  • Caiping Hu,
  • Yuan Wang and
  • Shuai Gao

11 August 2024

Impermeability and water blocking are crucial for remediating shallow groundwater contamination. Traditional methods often employ curtain-grouting technology to create impermeable layers. However, cement slurry curing is irreversible, leading to perm...

(This article belongs to the Section Hydrogeology)
  • Article
  • Open Access
534 Views
19 Pages

2 July 2026

Currently, existing studies primarily perform damage simulations based on random aggregate mesoscale models of concrete. In contrast, research on freeze–thaw numerical simulations based on realistic concrete mesostructural models remains relati...

(This article belongs to the Special Issue Advances in Cementitious Materials: Properties, Microstructure and Applications)
  • Article
  • Open Access
588 Views
29 Pages

Response Surface Optimization of Apple Powder Incorporation and Processing Conditions for Improving the Quality of Whipped Yeast-Free Frozen Dough and Bread

  • Sholpan Tursunbayeva,
  • Auyelbek Iztayev,
  • Zhuldyz Nurgozhina,
  • Madina Yakiyayeva,
  • Bauyrzhan Iztayev,
  • Bayan Muldabekova,
  • Maxat Mamyrayev,
  • Diana Abdraimova and
  • Fatima Yermetaeva

4 August 2026

Mechanically aerated yeast-free dough is particularly susceptible to freeze–thaw damage because its porous structure is formed before freezing and cannot be restored during thawing due to the absence of fermentation. This study investigated the...

(This article belongs to the Section Food Process Engineering)
  • Article
  • Open Access
4 Citations
2,777 Views
19 Pages

2 September 2022

The freeze-sealing pipe roof (FSPR) method was applied as an innovative construction technology to the Gongbei Tunnel of the Hong Kong–Zhuhai–Macau Bridge. A freezing scheme involving master freezing tubes, enhancing freezing tubes, and limiting free...

(This article belongs to the Special Issue Building Physics, Structural and Safety Engineering)
  • Article
  • Open Access
17 Citations
3,878 Views
15 Pages

Accelerated Production of Biopharmaceuticals via Microwave-Assisted Freeze-Drying (MFD)

  • Nicole Härdter,
  • Raimund Geidobler,
  • Ingo Presser and
  • Gerhard Winter

Recently, attention has been drawn to microwave-assisted freeze-drying (MFD), as it drastically reduces the typically long drying times of biopharmaceuticals in conventional freeze-drying (CFD). Nevertheless, previously described prototype machines l...

(This article belongs to the Special Issue Advance in Pharmaceutical Engineering: PAT and Model-Based Approach for QbD and Continuous Processes)
  • Article
  • Open Access
45 Citations
8,961 Views
11 Pages

17 June 2021

Spray-drying and freeze-drying can extend the shelf life and improve the transportability of high-nutritional foods such as Liluva (processing water of legumes). Nonetheless, the effects of these processes on nutrition, physiochemical properties, and...

(This article belongs to the Special Issue Physicochemical and Sensory Evaluation of Grain-Based Food)
  • Article
  • Open Access
100 Citations
16,861 Views
15 Pages

The Impact of Freeze-Drying Conditions on the Physico-Chemical Properties and Bioactive Compounds of a Freeze-Dried Orange Puree

  • Marilú A. Silva-Espinoza,
  • Charfedinne Ayed,
  • Timothy Foster,
  • María del Mar Camacho and
  • Nuria Martínez-Navarrete

30 December 2019

Fruits are essential for a healthy diet, as they contribute to the prevention of cardiovascular diseases and some cancers, which is attributed to their high bioactive compound content contributing to their antioxidant capacity. Nevertheless, fruits h...

(This article belongs to the Special Issue Freeze-Drying Technology in Foods)
  • Article
  • Open Access
4 Citations
1,126 Views
19 Pages

10 April 2025

This study explored the feasibility of applying transcritical CO2 in an artificial ground freezing method. By carrying out indoor modeling tests, the temperature field evolution law and the development characteristics of the freezing front during the...

(This article belongs to the Special Issue Optimization of Complex Engineering Systems and Application of Advanced Digital and Intelligent Technologies)
  • Article
  • Open Access
31 Citations
6,005 Views
23 Pages

The Impact of Drying Methods on the Quality of Blanched Yellow Mealworm (Tenebrio molitor L.) Larvae

  • Radosław Bogusz,
  • Joanna Bryś,
  • Anna Onopiuk,
  • Katarzyna Pobiega,
  • Aneta Tomczak,
  • Przemysław Łukasz Kowalczewski,
  • Katarzyna Rybak and
  • Małgorzata Nowacka

3 August 2024

The growing world population necessitates the implementation of appropriate processing technologies for edible insects. The objective of this study was to examine the impact of distinct drying techniques, including convective drying at 70 °C (70C...

  • Review
  • Open Access
4 Citations
1,626 Views
20 Pages

8 March 2026

Against the backdrop of global warming, changes in the frequency and intensity of freeze–thaw cycles in cold regions profoundly impact soil physical structure. This review examines the mechanisms by which freeze–thaw cycles influence soil...

(This article belongs to the Section Earth Sciences)
  • Review
  • Open Access
113 Citations
13,209 Views
35 Pages

Antioxidant Activity in Frozen Plant Foods: Effect of Cryoprotectants, Freezing Process and Frozen Storage

  • Lilia Neri,
  • Marco Faieta,
  • Carla Di Mattia,
  • Giampiero Sacchetti,
  • Dino Mastrocola and
  • Paola Pittia

17 December 2020

The antioxidant activity (AOA) of plant foods is recognized as an index of the potential health benefits resulting from their consumption. Due to their high perishability and seasonality, plant foods are largely consumed or used as processed products...

(This article belongs to the Special Issue Changes during Food Freezing and Frozen Storage)
  • Article
  • Open Access
9 Citations
3,425 Views
16 Pages

Ways to Improve the Efficiency of Devices for Freezing of Small Products

  • Oleg Bazaluk,
  • Nikolai Struchaiev,
  • Serhii Halko,
  • Oleksandr Miroshnyk,
  • Larysa Bondarenko,
  • Oleksandr Karaiev and
  • Vitalii Nitsenko

25 March 2022

It has been established that one of the main problems in the technology of the production of loose food products is the sticking of vegetables or fruits into one block. It has been proven that one of the steps to solve this problem is the use of berr...

(This article belongs to the Special Issue Advanced Designs of Materials, Machines and Processes in a Circular Economy)
  • Article
  • Open Access
18 Citations
4,391 Views
22 Pages

Development and Application of a Mechanistic Cooling and Freezing Model of the Spin Freezing Step within the Framework of Continuous Freeze-Drying

  • Gust Nuytten,
  • Susan Ríos Revatta,
  • Pieter-Jan Van Bockstal,
  • Ashish Kumar,
  • Joris Lammens,
  • Laurens Leys,
  • Brecht Vanbillemont,
  • Jos Corver,
  • Chris Vervaet and
  • Thomas De Beer

During the spin freezing step of a recently developed continuous spin freeze-drying technology, glass vials are rapidly spun along their longitudinal axis. The aqueous drug formulation subsequently spreads over the inner vial wall, while a cold gas f...

(This article belongs to the Special Issue New Trends in Freeze-Drying of Pharmaceutical Products)

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