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  • Article
  • Open Access
10 Citations
6,672 Views
12 Pages

Comparative Evaluation of Dental Enamel Microhardness Following Various Methods of Interproximal Reduction: A Vickers Hardness Tester Investigation

  • Dan-Cosmin Serbanoiu,
  • Aurel-Claudiu Vartolomei,
  • Dana-Valentina Ghiga,
  • Silvia Izabella Pop,
  • Irinel Panainte,
  • Marioara Moldovan,
  • Codruta Sarosi,
  • Ioan Petean,
  • Marie-Jose Boileau and
  • Mariana Pacurar

Interproximal enamel reduction, also known as stripping, is a common orthodontic procedure that reduces the mesiodistal diameter of teeth, allowing for a balance of available space in dental arches. The aim of this study was to assess the enamel surf...

(This article belongs to the Section Molecular and Translational Medicine)
  • Article
  • Open Access
8 Citations
2,326 Views
10 Pages

Assessment of Change in Enamel Color and Surface Hardness Following the Use of ICON Resin Infiltration and Remineralizing Agent: An In Vitro Study

  • Naif Almosa,
  • Khalid Alaman,
  • Fares Alkhudairi,
  • Muhannad Alhaqbani,
  • Mohammed Alshalawi and
  • Rahaf Zawawi

10 December 2024

This study aimed to evaluate the change in enamel color and surface micro-hardness following the use of resin-infiltration concept material (ICON) and casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP) remineralizing agent. Fifty-f...

(This article belongs to the Special Issue Orthodontic Materials: Properties and Effectiveness of Use)
  • Article
  • Open Access
21 Citations
7,234 Views
15 Pages

Enamel Remineralization Competence of a Novel Fluoride-Incorporated Bioactive Glass Toothpaste—A Surface Micro-Hardness, Profilometric, and Micro-Computed Tomographic Analysis

  • Imran Farooq,
  • Saqib Ali,
  • Faraz Ahmed Farooqi,
  • Jehan AlHumaid,
  • Mashael Binhasan,
  • Sara Shabib,
  • Fahim Vohra and
  • Tariq Abduljabbar

9 November 2021

This study aimed to analyze the enamel remineralization efficacy of a novel fluoridated bioactive glass (F-BG) toothpaste compared to a standard fluoride toothpaste. Seventy-two enamel blocks (N = 72) were divided into groups of twenty-four blocks ac...

  • Article
  • Open Access
3 Citations
3,870 Views
11 Pages

28 January 2022

Although dental prosthesis materials such as metal alloys, ceramics, and cured resin composite have long been utilized to restore teeth, their bond strength and hardness values are not well matched to human enamel. Prosthesis detachment and opposing...

(This article belongs to the Special Issue Advanced Polymer Composite Materials: Processing, Modeling, Properties and Applications)
  • Article
  • Open Access
27 Citations
3,829 Views
15 Pages

Flavonoid Baicalein Suppresses Oral Biofilms and Protects Enamel Hardness to Combat Dental Caries

  • Hong Chen,
  • Sihong Xie,
  • Jing Gao,
  • Liwen He,
  • Wenping Luo,
  • Yunhao Tang,
  • Michael D. Weir,
  • Thomas W. Oates,
  • Hockin H. K. Xu and
  • Deqin Yang

13 September 2022

The objectives of this study were to investigate the effects of a novel method using flavonoids to inhibit Streptococcus mutans (S. mutans), Candida albicans (C. albicans) and dual-species biofilms and to protect enamel hardness in a biofilm-based ca...

(This article belongs to the Section Biochemistry)
  • Feature Paper
  • Article
  • Open Access
13 Citations
4,975 Views
13 Pages

Effect of a Self-Assembly Peptide on Surface Roughness and Hardness of Bleached Enamel

  • Gabriela de A. P. Magalhães,
  • May Anny A Fraga,
  • Isaac J. de Souza Araújo,
  • Rafael R. Pacheco,
  • Américo B. Correr and
  • Regina M. Puppin-Rontani

After bleaching, enamel surfaces are damaged, contributing to erosion and tooth sensitivity. Although fluoride is used after bleaching to try and revert alterations, it is not capable of repairing tooth structure. This study compared the effect of a...

(This article belongs to the Special Issue Feature Papers in Dental Biomaterials)
  • Article
  • Open Access
16 Citations
5,993 Views
11 Pages

16 July 2024

The aim of the study was to compare the hardness, coefficient of friction, and wear experienced by four different ceramic samples: 3Y-TZP zirconium oxide ceramics—Zi—Ceramill Zi (Amman Girrbach), 5Y-PSZ transparent zirconium oxide ceramic...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
3 Citations
1,707 Views
14 Pages

Remineralizing Effect of Three Fluorinated Varnishes on Dental Enamel Analyzed by Raman Spectroscopy, Roughness, and Hardness Surface

  • Karla Itzel Pineda-Domínguez,
  • Samuel Eloy Morales-Gonzalez,
  • Sandra E. Rodil,
  • Isela Lizbeth Arredondo-Velazquez,
  • Nelly Rivera-Yañez,
  • Cesar Adolfo Callejas-Gomez,
  • Oscar Nieto-Yañez and
  • Cecilia Carlota Barrera-Ortega

17 September 2025

Dental caries is a prevalent health condition affecting 87% of the population. The application of fluorinated varnishes to incipient lesions promotes remineralization. To evaluate the remineralizing effect of three fluorinated varnishes through chemi...

(This article belongs to the Special Issue Surface Properties of Dental Materials and Instruments, 3rd Edition)
  • Article
  • Open Access
31 Citations
5,961 Views
11 Pages

A Comparative Evaluation of Nanohydroxyapatite-Enriched Hydrogen Peroxide Home Bleaching System on Color, Hardness and Microstructure of Dental Enamel

  • Riccardo Monterubbianesi,
  • Vincenzo Tosco,
  • Tiziano Bellezze,
  • Giampaolo Giuliani,
  • Mutlu Özcan,
  • Angelo Putignano and
  • Giovanna Orsini

4 June 2021

This study aimed to evaluate two hydrogen peroxide (HP)-based at-home bleaching systems in order to analyze whether nano-hydroxyapatite (nHA) addition may represent a reliable and safe solution for tooth whitening without altering dental microstructu...

(This article belongs to the Special Issue Novel Biomaterials and Technology for Dental Clinical Applications)
  • Article
  • Open Access
25 Citations
4,241 Views
16 Pages

Novel Nanocomposite Inhibiting Caries at the Enamel Restoration Margins in an In Vitro Saliva-Derived Biofilm Secondary Caries Model

  • Wen Zhou,
  • Xinyu Peng,
  • Xuedong Zhou,
  • Andrea Bonavente,
  • Michael D. Weir,
  • Mary Anne S. Melo,
  • Satoshi Imazato,
  • Thomas W. Oates,
  • Lei Cheng and
  • Hockin H. K. Xu

2 September 2020

Secondary caries often occurs at the tooth-composite margins. This study developed a novel bioactive composite containing DMAHDM (dimethylaminohexadecyl methacrylate) and NACP (nanoparticles of amorphous calcium phosphate), inhibiting caries at the e...

(This article belongs to the Special Issue Recent Advances in Dental Materials and Biomaterials)
  • Article
  • Open Access
3 Citations
3,628 Views
16 Pages

Microhardness and Chemical Composition of Different Metallic Brackets: An In Vitro Study

  • Marine Colmant,
  • Paul Fawaz,
  • Kenneth Stanton,
  • Oisin MacMichael and
  • Bart Vande Vannet

24 August 2023

The purpose of the study is to compare the hardness of different metallic brackets to enamel and to determine their chemical composition and microstructure. Five metallic brackets (0.022″ × 0.028″ inch) from seven orthodontic firms...

(This article belongs to the Section Dental Materials)
  • Article
  • Open Access
11 Citations
5,939 Views
21 Pages

Fluoride Casein Phosphopeptide and Tri-Calcium Phosphate Treatments for Enamel Remineralization: Effects on Surface Properties and Biofilm Resistance

  • Cecilia Carlota Barrera-Ortega,
  • Sandra E. Rodil,
  • Phaedra Silva-Bermudez,
  • Arturo Delgado-Cardona,
  • Argelia Almaguer-Flores and
  • Gina Prado-Prone

30 May 2025

Objectives: This study aimed to compare in vitro the protective effect of two enamel remineralizing agents, a varnish containing β-tricalcium phosphate with sodium fluoride (β-TCP-F) and a paste containing casein phosphopeptide-amorphous ca...

(This article belongs to the Special Issue Dental Materials Design and Application)
  • Article
  • Open Access
2 Citations
1,331 Views
13 Pages

The Microhardness and Chemical Composition of Different Ceramic Self-Ligating Brackets: An In Vitro Study

  • Mallaury Martinez,
  • Paul Fawaz,
  • Patrick El Sayegh,
  • Christophe Rapin and
  • Bart Vande Vannet

23 June 2025

Objectives: The aim of this study was to compare the hardness, chemical composition, and microstructure of various self-ligating ceramic orthodontic brackets and enamel. Methods: Sixty ceramic brackets (0.022″ × 0.028″) from six dif...

(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
  • Article
  • Open Access
29 Citations
4,075 Views
9 Pages

In Vitro Re-Hardening of Bleached Enamel Using Mineralizing Pastes: Toward Preventing Bacterial Colonization

  • Andrea Scribante,
  • Claudio Poggio,
  • Simone Gallo,
  • Paolo Riva,
  • Antonella Cuocci,
  • Manuel Carbone,
  • Carla Renata Arciola and
  • Marco Colombo

11 February 2020

The search for materials able to remineralize human hard tissues is a modern medical challenge. In this study, the protective effect on the enamel microhardness by a paste based on hydroxyapatite and sodium fluoride (Remin Pro) was evaluated after tw...

(This article belongs to the Special Issue Anti-Infective Materials)
  • Article
  • Open Access
12 Citations
8,406 Views
9 Pages

Evaluation of the Efficacy of CPP-ACP Remineralizing Mousse in MIH White and Yellow Opacities—In Vitro Vickers Microhardness Analysis

  • Inês Cardoso-Martins,
  • Sofia Arantes-Oliveira,
  • Ana Coelho,
  • Sofia Pessanha and
  • Paula F. Marques

2 October 2022

Remineralization of tooth enamel can be partially achieved by the application of a casein phosphopeptides and amorphous phosphate (CPP-ACP) complex. However, evidence to support its effectiveness in Molar-incisor-hypomineralization (MIH)-affected tee...

(This article belongs to the Special Issue Studies on Dental Enamel)
  • Article
  • Open Access
8 Citations
2,357 Views
18 Pages

S. mutans Antisense vicK RNA Over-Expression Plus Antibacterial Dimethylaminohexadecyl Methacrylate Suppresses Oral Biofilms and Protects Enamel Hardness in Extracted Human Teeth

  • Shuang Yu,
  • Mengmeng Xu,
  • Zheng Wang,
  • Yang Deng,
  • Hockin H. K. Xu,
  • Michael D. Weir,
  • Negar Homayounfar,
  • Guadalupe Garcia Fay,
  • Hong Chen and
  • Deqin Yang

21 August 2024

Streptococcus mutans (S. mutans) antisense vicK RNA (ASvicK) is a non-coding RNA that regulates cariogenic virulence and metabolic activity. Dimethylaminohexadecyl methacrylate (DMAHDM), a quaternary ammonium methacrylate used in dental materials, ha...

  • Article
  • Open Access
19 Citations
7,525 Views
13 Pages

Paediatric Over-the-Counter (OTC) Oral Liquids Can Soften and Erode Enamel

  • Dan Zhao,
  • James Kit-Hon Tsoi,
  • Hai Ming Wong,
  • Chun Hung Chu and
  • Jukka P. Matinlinna

11 May 2017

This study investigated the softening and erosive effects of various paediatric over-the-counter (OTC) oral liquids on deciduous teeth. Twenty sectioned and polished deciduous enamel blocks were ground on the buccal surface (2 × 2 mm2) and randomly d...

(This article belongs to the Special Issue Current Concepts on Erosive Tooth Wear)
  • Article
  • Open Access
4 Citations
8,994 Views
10 Pages

Assessing the Impact of Varied Dark Chocolate Concentrations on Enamel and Dentine Microhardness

  • Niaz Hamaghareeb Hamasaeed,
  • Intesar Saadallah Toma,
  • Adil Othman Abdullah and
  • Shakhawan Kadir Kadir

31 December 2023

(1) Background: The objective of the current investigation was to determine how different dark chocolate concentrations impacted the enamel and dentine microhardness. (2) Methods: Twenty noncarious premolar teeth extracted for orthodontic reasons wer...

(This article belongs to the Section Materials Science and Engineering)
  • Article
  • Open Access
6 Citations
3,213 Views
9 Pages

27 November 2023

Aim: This study aims to assess the impact of various reparative remineralizing agents, specifically topical fluoride (TF) and a combination of a carbon dioxide laser (CO2 laser) with TF, as well as regenerative agents such as Curodont™ Repair a...

(This article belongs to the Section Applied Dentistry and Oral Sciences)
  • Article
  • Open Access
4 Citations
3,551 Views
15 Pages

Effect of the Addition of Graphene Flakes on the Physical and Biological Properties of Composite Paints

  • Natalia Bartczak,
  • Jerzy Kowalczyk,
  • Robert Tomala,
  • Mariusz Stefanski,
  • Damian Szymański,
  • Maciej Ptak,
  • Wiesław Stręk,
  • Konrad Szustakiewicz,
  • Tomasz Kurzynowski and
  • Paweł Głuchowski
  • + 3 authors

21 August 2023

In this study, graphene flakes were obtained using an electrolytic method and characterized using X-ray diffraction (XRD), Raman and FTIR spectroscopy, scanning and transmission electron microscopy (SEM/TEM). Graphene-based composites with varying co...

(This article belongs to the Special Issue Feature Papers in Applied Chemistry 2.0)
  • Article
  • Open Access
6 Citations
4,885 Views
7 Pages

Evaluation of Different Dentifrice Compositions for Increasing the Hardness of Demineralized Enamel: An in Vitro Study

  • Pedro Henrique Cabral Oliveira,
  • Marcia Regina Cabral Oliveira,
  • Luiz Henrique Cabral Oliveira,
  • Ravana Angelini Sfalcin,
  • Marcelo Mendes Pinto,
  • Ellen Perin Rosa,
  • Alessandro Melo Deana,
  • Anna Carolina Ratto Tempestini Horliana,
  • Paulo Francisco César and
  • Sandra Kalil Bussadori

4 February 2019

This study aimed to evaluate microhardness of a dentifrice containing fluoride and arginine compared to a positive control (fluoride only) and a negative control (no fluoride) on sound and demineralized bovine enamel surfaces. Specimens were randomly...

  • Article
  • Open Access
2 Citations
2,500 Views
17 Pages

ADAM10 Expression by Ameloblasts Is Essential for Proper Enamel Formation

  • Shifa Shahid,
  • Yuanyuan Hu,
  • Fatma Mohamed,
  • Lara Rizzotto,
  • Michelle C. Layana,
  • Daniel T. Fleming,
  • Petros Papagerakis,
  • Brian L. Foster,
  • James P. Simmer and
  • John D. Bartlett

7 December 2024

ADAM10 is a multi-functional proteinase that can cleave approximately 100 different substrates. Previously, it was demonstrated that ADAM10 is expressed by ameloblasts, which are required for enamel formation. The goal of this study was to determine...

(This article belongs to the Special Issue Molecular Metabolism of Ameloblasts in Tooth Development)
  • Feature Paper
  • Review
  • Open Access
24 Citations
5,049 Views
15 Pages

Vibrational Imaging Techniques for the Characterization of Hard Dental Tissues: From Bench-Top to Chair-Side

  • Giovanna Orsini,
  • Giulia Orilisi,
  • Valentina Notarstefano,
  • Riccardo Monterubbianesi,
  • Flavia Vitiello,
  • Vincenzo Tosco,
  • Alessia Belloni,
  • Angelo Putignano and
  • Elisabetta Giorgini

15 December 2021

Currently, various analytical techniques, including scanning electron microscopy, X-Ray diffraction, microcomputed tomography, and energy dispersive X-ray spectroscopy, are available to study the structural or elemental features of hard dental tissue...

(This article belongs to the Special Issue Imaging Techniques for Oral and Dental Applications)
  • Article
  • Open Access
342 Views
20 Pages

13 July 2026

Background and Objectives: In-office bleaching is one of the most requested aesthetic procedures, but its biomechanical aftermath on enamel—particularly the recovery trajectory of microhardness, surface roughness, and erosive vulnerability&mdas...

  • Correction
  • Open Access
742 Views
2 Pages

Correction: Pineda-Domínguez et al. Remineralizing Effect of Three Fluorinated Varnishes on Dental Enamel Analyzed by Raman Spectroscopy, Roughness, and Hardness Surface. Coatings 2025, 15, 1091

  • Karla Itzel Pineda-Domínguez,
  • Samuel Eloy Morales-Gonzalez,
  • Sandra E. Rodil,
  • Isela Lizbeth Arredondo-Velazquez,
  • Nelly Rivera-Yañez,
  • Cesar Adolfo Callejas-Gomez,
  • Oscar Nieto-Yañez and
  • Cecilia Carlota Barrera-Ortega

19 December 2025

Error in Author Name [...]

  • Article
  • Open Access
11 Citations
3,672 Views
10 Pages

Mapping of Nanomechanical Properties of Enamel Surfaces Due to Orthodontic Treatment by AFM Method

  • Monika Machoy,
  • Sławomir Wilczyński,
  • Liliana Szyszka-Sommerfeld,
  • Krzysztof Woźniak,
  • Anna Deda and
  • Sławomir Kulesza

26 April 2021

Background: Atomic force microscopy imaging was used to study the structural topography of enamel crystals in healthy and affected enamel. The correlation of topographic images with nanomechanical properties allows for the assessment of morphology an...

(This article belongs to the Special Issue Application of Image Processing in Medicine)
  • Article
  • Open Access
2 Citations
4,063 Views
14 Pages

The Efficacy of Remineralizing Materials on Artificial Enamel Lesions: An In Vitro Study

  • Gustė Klimaitė,
  • Arūnas Vasiliauskas,
  • Pranas Grinkevičius,
  • Dominyka Grinkevičienė and
  • Deivydas Šapalas

6 March 2025

Background and Objectives: Contemporary caries treatment seeks to preserve hard dental tissues as well as to promote lesion remineralization and biological tissue regeneration. While fluoride-based treatments remain the gold standard, their effective...

(This article belongs to the Topic Advances in Dental Materials)
  • Article
  • Open Access
22 Citations
4,966 Views
13 Pages

Wear of Polymer-Infiltrated Ceramic Network Materials against Enamel

  • Jumpei Tokunaga,
  • Hiroshi Ikeda,
  • Yuki Nagamatsu,
  • Shuji Awano and
  • Hiroshi Shimizu

25 March 2022

Polymer-infiltrated ceramic network materials (PICNs) have high mechanical compatibility with human enamel. However, the wear properties of PICN against natural human enamel have not yet been clarified. We investigated the in vitro two-body wear beha...

(This article belongs to the Special Issue Advanced Materials for Restorative Dental Sciences)
  • Article
  • Open Access
11 Citations
3,333 Views
15 Pages

Wear Behavior between Aesthetic Restorative Materials and Bovine Tooth Enamel

  • Akihiko Hatanaka,
  • Tomofumi Sawada,
  • Kazuyo Sen,
  • Takahiro Saito,
  • Kaori Sasaki,
  • Tomoko Someya,
  • Masayuki Hattori and
  • Shinji Takemoto

28 July 2022

Tooth enamel wear occurs because of daily mastication and occlusion. This study investigated the wear behavior of bovine teeth against aesthetic restorative materials in vitro. Abrader specimens were fabricated using four tooth-colored restorative ma...

(This article belongs to the Section Manufacturing Processes and Systems)
  • Article
  • Open Access
9 Citations
4,082 Views
21 Pages

Proteomic Analyses Discern the Developmental Inclusion of Albumin in Pig Enamel: A New Model for Human Enamel Hypomineralization

  • Ana Gil-Bona,
  • Hakan Karaaslan,
  • Baptiste Depalle,
  • Rosalyn Sulyanto and
  • Felicitas B. Bidlack

25 October 2023

Excess albumin in enamel is a characteristic of the prevalent developmental dental defect known as chalky teeth or molar hypomineralization (MH). This study uses proteomic analyses of pig teeth to discern between developmental origin and post-eruptiv...

(This article belongs to the Section Biochemistry)
  • Article
  • Open Access
22 Citations
4,513 Views
13 Pages

Hydroxyapatite Film Coating by Er:YAG Pulsed Laser Deposition Method for the Repair of Enamel Defects

  • Liji Chen,
  • Shigeki Hontsu,
  • Satoshi Komasa,
  • Ei Yamamoto,
  • Yoshiya Hashimoto and
  • Naoyuki Matsumoto

6 December 2021

There are treatments available for enamel demineralization or acid erosion, but they have limitations. We aimed to manufacture a device that could directly form a hydroxyapatite (HAp) film coating on the enamel with a chairside erbium-doped yttrium a...

(This article belongs to the Special Issue Advances in Dental Bio-Nanomaterials)
  • Article
  • Open Access
25 Citations
7,824 Views
9 Pages

Effects of Fluoride on Two Chemical Models of Enamel Demineralization

  • Ollie Yiru Yu,
  • May Lei Mei,
  • Irene Shuping Zhao,
  • Edward Chin-Man Lo and
  • Chun-Hung Chu

27 October 2017

This study evaluated the effects of fluoride on subsurface enamel demineralization induced by two commonly used chemical models. Forty-eight enamel blocks were demineralized at pH = 5.0 by an acetate buffer (Group 1), a lactate buffer (Group 2), an a...

(This article belongs to the Section Biomaterials)
  • Review
  • Open Access
8 Citations
5,887 Views
17 Pages

12 November 2021

The distinct architecture of native enamel gives it its exquisite appearance and excellent intrinsic-extrinsic fracture toughening properties. However, damage to the enamel is irreversible. At present, the clinical treatment for enamel lesion is an i...

  • Article
  • Open Access
18 Citations
6,500 Views
14 Pages

Development of High-Performance Enamel Coating on Grey Iron by Low-Temperature Sintering

  • Dan Song,
  • Ren Tang,
  • Falin Yang,
  • Yanxin Qiao,
  • Jiapeng Sun,
  • Jinghua Jiang and
  • Aibin Ma

4 November 2018

In this study, we report on a low-temperature sintered enamel coating with a high-strength bonding and wear-resistance that protected a grey cast iron substrate. The SiO2–Al2O3–B2O3 composited prescription for the enamel coating was modif...

(This article belongs to the Special Issue Thin Film Fabrication and Surface Techniques)
  • Editorial
  • Open Access
3 Citations
2,669 Views
8 Pages

Advances in Biomimetic Scaffolds for Hard Tissue Surgery

  • Ryszard Uklejewski and
  • Mariusz Winiecki

Hard tissues are living mineralized tissues that possess a high degree of hardness and are found in organs such as bones and teeth (enamel, dentin, and cementum) [...]

(This article belongs to the Special Issue Biomimetic Scaffolds for Hard Tissue Surgery)
  • Article
  • Open Access
1 Citations
1,152 Views
10 Pages

30 July 2025

Background: Dental enamel demineralization is a critical early event in the development of dental caries. To address this, bioactive compounds have been explored for their potential to mitigate enamel demineralization and promote remineralization. Pr...

(This article belongs to the Special Issue Dental Biomaterials and Implants: Latest Advances and Prospects)
  • Feature Paper
  • Article
  • Open Access
5 Citations
2,624 Views
20 Pages

In Vitro Evaluation of Chemical and Microhardness Alterations in Human Enamel Induced by Three Commercial In-Office Bleaching Agents

  • Berivan Laura Rebeca Buzatu,
  • Atena Galuscan,
  • Ramona Dumitrescu,
  • Roxana Buzatu,
  • Magda Mihaela Luca,
  • Octavia Balean,
  • Gabriela Vlase,
  • Titus Vlase,
  • Iasmina-Mădălina Anghel and
  • Daniela Jumanca
  • + 3 authors

6 August 2025

Background/Objectives: In-office bleaching commonly employs high concentrations of hydrogen peroxide (HP) or carbamide peroxide (CP), which may compromise enamel integrity. This in vitro paired-design study aimed to compare the chemical and mechanica...

(This article belongs to the Special Issue Advances in Esthetic Dentistry)
  • Review
  • Open Access
28 Citations
13,113 Views
15 Pages

30 August 2012

Human enamel development of the permanent teeth takes place during childhood and stresses encountered during this period can have lasting effects on the appearance and structural integrity of the enamel. One of the most common examples of this is the...

(This article belongs to the Special Issue Cellular Stress Response)
  • Article
  • Open Access
2 Citations
2,236 Views
14 Pages

Effect of Quercetin-Doped Hydrogen Peroxide Gels on Enamel Properties: An In Vitro Study

  • Renata de Oliveira Alves,
  • Gabriel Pereira Nunes,
  • Tamires Passadori Martins,
  • Priscila Toninatto Alves de Toledo,
  • Matheus Henrique Faccioli Ragghianti and
  • Alberto Carlos Botazzo Delbem

27 April 2025

This in vitro study evaluated the effects of incorporating quercetin (QC) at varying concentrations (0.25%, 0.5%, and 1%) into a 35% hydrogen peroxide (H2O2) bleaching gel on esthetic outcomes, enamel hardness and roughness, and H2O2 transamelodentin...

(This article belongs to the Special Issue Global Excellence in Bioactive Gels)
  • Article
  • Open Access
1 Citations
1,287 Views
18 Pages

The Influence of Multi-Level Structure on the Bearing and Crack Propagation Mechanism of Tooth Enamel

  • Yiyun Kong,
  • Haiyan Xin,
  • Siqi Zhu,
  • Mengmeng Chen,
  • Yujie Fan and
  • Jing Xia

30 October 2025

Dental enamel exhibits a unique combination of high hardness and high toughness. This outstanding mechanical property is closely tied to its multi-scale hierarchical structure. In this study, rat tooth enamel was selected as the research object, the...

(This article belongs to the Section Surface Coatings for Biomedicine and Bioengineering)
  • Article
  • Open Access
12 Citations
4,137 Views
9 Pages

Calcium Phosphate Nanoclusters for the Repair of Tooth Enamel Erosion

  • Chia-Hsien Wang,
  • Chinmaya Mutalik,
  • Sibidou Yougbaré,
  • Nai-Chia Teng and
  • Tsung-Rong Kuo

10 June 2022

The artificial repair of tooth enamel is still an urgent requirement because it has a complicated and well-arranged structure. Herein, calcium phosphate nanoclusters (CaP NCs) were synthesized, via a facile approach, for application in the repair of...

(This article belongs to the Special Issue Review of Nanocomposite Materials)
  • Article
  • Open Access
3 Citations
7,942 Views
9 Pages

Evaluation of Enamel Acid Resistance and Whitening Effect of the CAP System

  • Naoko Miki,
  • Yasuo Miake,
  • Shinji Shimoda and
  • Hiroyuki Mishima

30 August 2022

This study aimed to compare the effectiveness of a novel professional tooth-strengthening system and a conventional caries-prevention method that involved the use of high fluoride concentrations, to determine whether the system has a whitening effect...

(This article belongs to the Special Issue Dental Materials and Their Clinical Applications II)
  • Article
  • Open Access
65 Citations
7,862 Views
20 Pages

A Chitosan–Agarose Polysaccharide-Based Hydrogel for Biomimetic Remineralization of Dental Enamel

  • Viorica Muşat,
  • Elena Maria Anghel,
  • Agripina Zaharia,
  • Irina Atkinson,
  • Oana Cătălina Mocioiu,
  • Mariana Buşilă and
  • Petrică Alexandru

2 August 2021

Developing multifunctional systems for the biomimetic remineralization of human enamel is a challenging task, since hydroxyapatite (HAP) rod structures of tooth enamel are difficult to replicate artificially. The paper presents the first report on th...

  • Article
  • Open Access
2,883 Views
17 Pages

Comparative Assessment of the Remineralization Potential of Five Modern Oral Health Products on Bovine Enamel

  • Aggeliki Lampousi,
  • Dimitrios Dionysopoulos,
  • Razia Z. Adam,
  • Spyros Papageorgiou,
  • Kosmas Tolidis and
  • Robert G. Hill

The purpose of this in vitro study was to evaluate the remineralization effect of five preventive treatments on bovine enamel after artificial caries challenge. Sixty sound bovine incisors were randomly distributed into six experimental groups (n = 1...

(This article belongs to the Special Issue Biomaterials in Conservative Dentistry and Prosthodontics (2nd Edition))
  • Article
  • Open Access
27 Citations
4,714 Views
12 Pages

Effect of Surface Roughness of Deciduous and Permanent Tooth Enamel on Bacterial Adhesion

  • Bernardo Teutle-Coyotecatl,
  • Rosalía Contreras-Bulnes,
  • Laura Emma Rodríguez-Vilchis,
  • Rogelio José Scougall-Vilchis,
  • Ulises Velazquez-Enriquez,
  • Argelia Almaguer-Flores and
  • Jesús Angel Arenas-Alatorre

The adhesion of some bacteria has been attributed to critical levels of roughness in hard tissues, which increases the risk of developing caries. The objective of this work was to assess the effect of deciduous and permanent tooth enamel surface roug...

(This article belongs to the Special Issue Biofilm-Related Infections in Healthcare)
  • Article
  • Open Access
5 Citations
3,002 Views
13 Pages

The Wear Behavior of Glass-Ceramic CAD/CAM Blocks against Bovine Enamel

  • Tomoko Someya,
  • Masaaki Kasahara,
  • Shinji Takemoto and
  • Masayuki Hattori

24 October 2023

The wear of enamel and crown restorative materials often occur by occlusion. The purpose of this study was to evaluate the wear volume between glass-ceramics used for CAD/CAM blocks (lithium disilicate: Initial LiSi block (LIS), IPS e.max CAD (IPS),...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
5 Citations
5,918 Views
13 Pages

In Vitro Investigation of Novel Peptide Hydrogels for Enamel Remineralization

  • Codruta Sarosi,
  • Alexandrina Muntean,
  • Stanca Cuc,
  • Ioan Petean,
  • Sonia Balint,
  • Marioara Moldovan and
  • Aurel George Mohan

27 December 2024

This study investigates the microstructure of dental enamel following demineralization and re-mineralization processes, using DIAGNOdent scores and images obtained via scanning electron microscopy (SEM), atomic force microscopy (AFM), and microhardne...

(This article belongs to the Special Issue Advanced Hydrogels: Preparation, Property and Biomedical Application (2nd Edition))
  • Article
  • Open Access
14 Citations
4,341 Views
17 Pages

Near-Surface Studies of the Changes to the Structure and Mechanical Properties of Human Enamel under the Action of Fluoride Varnish Containing CPP–ACP Compound

  • Izabela Świetlicka,
  • Damian Kuc,
  • Michał Świetlicki,
  • Marta Arczewska,
  • Siemowit Muszyński,
  • Ewa Tomaszewska,
  • Adam Prószyński,
  • Krzysztof Gołacki,
  • Jerzy Błaszczak and
  • Maria Mielnik-Błaszczak
  • + 2 authors

Changes to the features of the enamel surface submitted to induced demineralisation and subsequent remineralisation were studied. The in vitro examination was conducted on polished slices of human molar teeth, divided in four groups: the untreated co...

(This article belongs to the Special Issue Application and Mechanism of Natural Compounds in Dentistry)
  • Article
  • Open Access
7 Citations
3,731 Views
15 Pages

Enamel Structure Defects in Kdf1 Missense Mutation Knock-in Mice

  • Pei Li,
  • Binghui Zeng,
  • Weihong Xie,
  • Xue Xiao,
  • Ling Lin,
  • Dongsheng Yu and
  • Wei Zhao

The Keratinocyte differentiation factor 1 (KDF1) is reported to take part in tooth formation in humans, but the dental phenotype of Kdf1 mutant mice has not been understood. Additionally, the role of the KDF1 gene in dental hard tissue development is...

(This article belongs to the Section Molecular Genetics and Genetic Diseases)
  • Review
  • Open Access
220 Citations
22,634 Views
25 Pages

Apatite Biominerals

  • Christèle Combes,
  • Sophie Cazalbou and
  • Christian Rey

5 April 2016

Calcium phosphate apatites offer outstanding biological adaptability that can be attributed to their specific physico-chemical and structural properties. The aim of this review is to summarize and discuss the specific characteristics of calcium phosp...

(This article belongs to the Special Issue Biomineralization: Towards a Unification of Concepts in Chemistry, Physics, Earth Sciences and Biology)

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