Dental Materials Design and Innovative Treatment Approach

A special issue of Dentistry Journal (ISSN 2304-6767). This special issue belongs to the section "Dental Materials".

Deadline for manuscript submissions: 20 October 2025 | Viewed by 40817

Special Issue Editors


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Guest Editor
Department of System Medicine, University of Rome “Tor Vergata”, 00133 Rome, Italy
Interests: dental materials

E-Mail Website
Guest Editor
Department of System Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy
Interests: dentistry; oral surgery; bone regeneration; periodontal diseases; facescan; digital dentistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, technological innovation has had exponential growth and this has also had positive implications in dentistry.

In the field of implantology, the development of bioactive surfaces and biomaterials has made it possible to enhance patient healing. In the field of prosthetics, the development of CAD-CAM technologies and the advent of intraoral and facial scanners have allowed a faster and increasingly tailor-made approach thanks also to the use of milled titanium bars and milled ceramic materials.

In the field of orthodontics, the advent of transparent aligners has drastically changed the approach to the patient in the developmental age.

This Special Issue is concerned with all aspects of all dental specialties dealing with this topic. The question we could ask ourselves is: what are the most interesting materials in all these fields of dentistry? How can the latest generation materials and technologies influence the patient care plan?

Prof. Dr. Patrizio Bollero
Dr. Francesco Gianfreda
Guest Editors

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Keywords

  • bioactive implant surfaces
  • bioactive biomaterials
  • digital technologies
  • CAD-CAM
  • orthodontic aligners

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Published Papers (25 papers)

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Editorial

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2 pages, 183 KiB  
Editorial
Dental Materials Design and Innovative Treatment Approach
by Francesco Gianfreda and Patrizio Bollero
Dent. J. 2023, 11(3), 85; https://doi.org/10.3390/dj11030085 - 17 Mar 2023
Cited by 3 | Viewed by 1778
Abstract
In recent years, technological innovation has had exponential growth, resulting in positive implications in dentistry [...] Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)

Research

Jump to: Editorial, Review, Other

20 pages, 6738 KiB  
Article
Biocompatible Inorganic PVD MeSiON Thin Films (Me = Cr or Zr) Used to Enhance the Bond Strength Between NiCr-Based Metallic Frameworks and Ceramic in Dental Restorations
by Mihaela Dinu, Cosmin Mihai Cotrut, Alina Vladescu (Dragomir), Florin Baciu, Anca Constantina Parau, Iulian Pana, Lidia Ruxandra Constantin and Catalin Vitelaru
Dent. J. 2025, 13(7), 318; https://doi.org/10.3390/dj13070318 - 14 Jul 2025
Viewed by 139
Abstract
Background/Objectives: The increasing demand for aesthetics in dentistry has driven significant advancements in both materials and techniques. The primary cause of ceramic detachment in dental restorations is extensive mechanical stress, which often results in detachment and clinical complications. This study aims to improve [...] Read more.
Background/Objectives: The increasing demand for aesthetics in dentistry has driven significant advancements in both materials and techniques. The primary cause of ceramic detachment in dental restorations is extensive mechanical stress, which often results in detachment and clinical complications. This study aims to improve the bond strength between NiCr-based metal frameworks and ceramic coatings by introducing biocompatible inorganic MeSiON thin films (Me = Cr or Zr) as interlayers. Methods: MeSiON coatings with a thickness of ~2 μm were deposited on NiCr alloy using cathodic arc evaporation. To tailor the stoichiometry, morphology, and mechanical properties of the coatings, the substrate bias voltage was varied: −50 V, −100 V, −150 V, −200 V. Structural and surface characterization was performed using SEM/EDS, XRD, profilometry, and contact angle analysis. The coating adhesion was evaluated by using standardized scratch testing, while the bond strength was evaluated using a three-point bending test. Results: The NiCr alloy exhibited a dendritic microstructure, and the ceramic layer consisted mainly of quartz, feldspar, kaolin, and ZrO2. ZrSiON coatings showed superior roughness, elemental incorporation, and adhesion compared to Cr-based coatings, these properties being further improved by increasing the substrate bias. The highest bond strength was achieved with a ZrSiON coating deposited at −200 V, a result we attributed to increased surface roughness and mechanical interlocking at the ceramic-metal interface. Conclusions: CrSiON and ZrSiON interlayers enhanced ceramic-to-metal adhesion in NiCr-based dental restorations. The enhancement in bond strength is primarily ascribed to substrate bias-induced modifications in the coating’s stoichiometry, roughness, and adhesion. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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13 pages, 3660 KiB  
Article
The Microhardness and Chemical Composition of Different Ceramic Self-Ligating Brackets: An In Vitro Study
by Mallaury Martinez, Paul Fawaz, Patrick El Sayegh, Christophe Rapin and Bart Vande Vannet
Dent. J. 2025, 13(7), 285; https://doi.org/10.3390/dj13070285 - 23 Jun 2025
Viewed by 236
Abstract
Objectives: The aim of this study was to compare the hardness, chemical composition, and microstructure of various self-ligating ceramic orthodontic brackets and enamel. Methods: Sixty ceramic brackets (0.022″ × 0.028″) from six different orthodontic firms (Damon® Clear 2, Genius® Crystal, Empower [...] Read more.
Objectives: The aim of this study was to compare the hardness, chemical composition, and microstructure of various self-ligating ceramic orthodontic brackets and enamel. Methods: Sixty ceramic brackets (0.022″ × 0.028″) from six different orthodontic firms (Damon® Clear 2, Genius® Crystal, Empower® 2 Clear, Clarity® Ultra, Alpine SL® Clear, and Experience Ceramic®) were tested using a microhardness tester and a scanning electron microscope (SEM) equipped with energy-dispersive spectroscopy (EDS). Results: The hardness of the ceramic brackets ranged from 1969.8 to 2567.3 VH. The statistical analysis using the Kruskal–Wallis and Mann–Whitney tests revealed significant differences in microhardness between most of the ceramic brackets. Additionally, this study found that passive self-ligating brackets exhibited a significantly higher hardness than that of active self-ligating brackets (p = 0.01). The SEM analysis showed that the variations in the oxygen and alumina composition between the six bracket types were also statistically significant (p = 0.01). Conclusions: Among all of the ceramic brackets tested, Alpine® brackets displayed the lowest hardness values, making them a potential choice for minimizing enamel damage. Notably, the hardness of self-ligating ceramic brackets was found to be at least six times greater than that of enamel, raising concerns about their potential to cause trauma to the enamel of antagonistic teeth. Consequently, the researchers recommend avoiding bonding ceramic brackets to the mandibular teeth or elevating occlusion with turbo-bites to prevent traumatic contact during treatment. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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14 pages, 2260 KiB  
Article
The Effect of Zirconia Material and the Height of the Ceramic Coping on the Strength of Hybrid Ti-Ceramic Abutments
by Aikaterini Anastasaki, Pranit Bora, Stefanos Kourtis and Chin Chuan Fu
Dent. J. 2025, 13(7), 284; https://doi.org/10.3390/dj13070284 - 23 Jun 2025
Viewed by 302
Abstract
The existing scientific literature lacks comprehensive information regarding the influence of zirconia crown height on debonding and fracture of the ceramic restorations on titanium base abutments. Additionally, there is a lack of comparative studies evaluating different types of zirconia as restorative options for [...] Read more.
The existing scientific literature lacks comprehensive information regarding the influence of zirconia crown height on debonding and fracture of the ceramic restorations on titanium base abutments. Additionally, there is a lack of comparative studies evaluating different types of zirconia as restorative options for screw-retained restorations. Purpose: The purpose of this study was to assess the fracture strength and the failure modes of the zirconia crown/titanium abutment complex by investigating the impact of increasing the height of zirconia crown and comparing different types of zirconia (3 mol% yttria-stabilized zirconia and translucent 5 mol% yttria-stabilized zirconia). Materials and Methods: Six groups of 10 specimens in each group were fabricated. Three groups of specimens (groups # 1, 2, and 3) were fabricated from 3Y zirconia in corresponding heights of 8, 10, and 12 mm. Three more groups (groups # 4, 5, and 6) were fabricated from 5Y zirconia in the same heights (8, 10 and 12 mm). All copings were bonded to 4 mm high titanium base abutments using dual-polymerization resin cement. The specimens underwent load cycling of 100,000 cycles with a force of 100 N. Subsequently, the specimens were loaded to compression until fracture and the failure mode was visually evaluated. Results: Statistically significant differences in fracture strength were noted among all tested groups. Conclusions: 3Y zirconia showed increased strength compared to 5Y in all heights. Ceramic copings with lower height showed increased strength compared to higher copings in both tested zirconia materials. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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13 pages, 3366 KiB  
Article
Compatibility of Dual-Cure Core Materials with Self-Etching Adhesives
by Zachary K. Greene, Augusto A. Robles and Nathaniel C. Lawson
Dent. J. 2025, 13(7), 276; https://doi.org/10.3390/dj13070276 - 20 Jun 2025
Viewed by 267
Abstract
Background/Objectives: A material incompatibility has been established between self-etching adhesives and amine-containing dual-cure resin composite materials used for core buildups. This study aims to compare the dentin bond strength of several amine-containing and amine-free core materials using self-etching adhesives with different pHs. [...] Read more.
Background/Objectives: A material incompatibility has been established between self-etching adhesives and amine-containing dual-cure resin composite materials used for core buildups. This study aims to compare the dentin bond strength of several amine-containing and amine-free core materials using self-etching adhesives with different pHs. Methods: Extracted human molars were mounted in acrylic and ground flat with 320-grit silicon carbide paper. Next, 520 specimens (n = 10/group) were assigned to a dual-cure core buildup material group (10 amine-containing, 2 amine-free, and 1 reference light-cure only bulk fill flowable composite) and assigned to a self-etching adhesive subgroup (pH levels of approximately 1.0, 3.0, and 4.0). Within 4 h of surface preparation, the adhesive corresponding to the specimen’s subgroup was applied and light-cured. Composite buttons for the assigned dual-cure core material of each group were placed using a bonding clamp apparatus, allowed to self-cure for 2 h at 37 °C, and then unclamped. An additional group with one adhesive (pH = 3.0) was prepared in which the dual-cure core materials were light-cured. The bonded specimens were stored in water at 37 °C for 24 h. The specimens were mounted on a testing clamp and de-bonded in a universal testing machine with a load applied to a circular notched-edge blade at a crosshead speed of 1 mm/min until bond failure. The maximum load divided by the area of the button was recorded as the shear bond strength. The data was analyzed via 2-way ANOVA. Results: The analysis of bond strength via 2-way ANOVA determined statistically significant differences between the adhesives, the core materials, and their interaction (p < 0.01). There was a general trend in shear bond strength for the adhesives, where pH 4.0 > 3.0 > 1.0. The amine-free core materials consistently demonstrated higher shear bond strengths as compared to the other core materials when chemically cured only. Light-curing improved bond strength for some materials with perceived incompatibility. Conclusions: The results of this study suggest that an incompatibility can exist between self-etching adhesives and dual-cure resin composite core materials. A decrease in the pH of the utilized adhesive corresponded to a decrease in the bond strength of dual-cure core materials when self-curing. This incompatibility may be minimized with the use of core materials formulated with amine-free chemistry. Alternatively, the dual-cure core materials may be light-cured. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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16 pages, 1251 KiB  
Article
Exploring Global Interest in Propolis, Nanosilver, and Biomaterials: Insights and Implications for Dentistry from Big Data Analytics
by Magdalena Sycińska-Dziarnowska, Liliana Szyszka-Sommerfeld, Krzysztof Woźniak and Gianrico Spagnuolo
Dent. J. 2025, 13(6), 253; https://doi.org/10.3390/dj13060253 - 6 Jun 2025
Viewed by 363
Abstract
Background: The growing demand for innovative biomaterials with antimicrobial properties has driven research into natural and synthetic compounds, such as propolis and nanosilver, known for their antimicrobial efficacy. Methods: This study uses Google Trends data to analyze global search interest in [...] Read more.
Background: The growing demand for innovative biomaterials with antimicrobial properties has driven research into natural and synthetic compounds, such as propolis and nanosilver, known for their antimicrobial efficacy. Methods: This study uses Google Trends data to analyze global search interest in five key terms—propolis, antimicrobial, antibacterial, nanosilver, and biomaterials—over a ten-year period (starting November 2014). The objective is to evaluate temporal variations, quantify correlations between the terms, and explore how external events, such as the COVID-19 pandemic, have influenced public and clinical interest in these topics. Search data were extracted, normalized, and analyzed using multivariate time series methods, including vector autoregression (VAR) modeling, Impulse Response Function (IRF) analysis, and forecast error variance decomposition (FEVD). Stability, causality, and inter-period relationships were assessed using statistical analysis, with results visualized through time series plots and impulse response coefficients. Results: Key findings reveal significant interdependencies between search terms, with surges in one often resulting in immediate or short-term increases in others. Notable trends include a marked increase in COVID-19 interest for nanosilver, propolis, and antibacterial, followed by a return to baseline levels, while antimicrobial maintained a sustained upward trajectory. Biomaterials experienced initial declines but later stabilized at elevated levels. Conclusions: These findings underscore the oscillating nature of public interest in antimicrobial and biomaterial innovations, highlighting opportunities for targeted research and commercialization. By adapting future material development to emerging trends and clinical needs, dentistry can use these insights to develop infection control strategies, improve restorative materials, and deal with persistent challenges such as antimicrobial resistance, peri-implantitis, and tooth caries treatment. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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14 pages, 2048 KiB  
Article
Factors Influencing the Selection of Materials and Luting Agents for Single-Crown Restorations
by Ahmad Alsahli, Mirza Rustum Baig, Jagan Kumar Baskaradoss, Shoug Alsanea and Athoub AlMousawi
Dent. J. 2025, 13(5), 207; https://doi.org/10.3390/dj13050207 - 9 May 2025
Viewed by 671
Abstract
Objective: Selecting suitable materials and luting agents for single crowns is critical yet challenging, as dentists must consider different factors. This study aimed to assess dentists’ preferences for materials and luting agents under different clinical conditions and evaluate the nonclinical factors influencing their [...] Read more.
Objective: Selecting suitable materials and luting agents for single crowns is critical yet challenging, as dentists must consider different factors. This study aimed to assess dentists’ preferences for materials and luting agents under different clinical conditions and evaluate the nonclinical factors influencing their preferences. Methods: A paper-based survey supplemented with photographs illustrating anterior and posterior single-crown preparation designs was used, incorporating three clinical scenarios for each as examples. Participants provided demographic data and were asked to select their preferred material and luting agent for each scenario. Comparisons between the crown material/luting agent choices and dentist/practice characteristics were performed. Significant differences were determined using the chi-square test. Results: Overall, 262 (87.3%) dentists participated in this survey. The top-selected material for anterior preparation designs was lithium disilicate; monolithic zirconia was the most selected for posterior preparation designs. Dual-cure resin was the most selected luting agent for all anterior and posterior clinical scenarios, except for posterior subgingival preparation design. There was a significant association between the dentist’s age and the selection of material and luting agent (p < 0.05) in all clinical scenarios, except for the luting agent selection in the posterior subgingival preparation designs (p < 0.05). Other nonclinical factors yielded mixed results; some preparation designs showed significant differences, while others did not, depending on the clinical scenario. Conclusions: Reliance on new materials and luting agents that require minimally invasive treatment with dental ceramics and resin cement is increasing. However, the choice of materials and luting agents is influenced by clinical presentation and nonclinical factors, making it crucial for dentists to be aware of these factors when selecting materials for single-crown restorations. Clinical Implications: An overall trend was observed for the use of strong monolithic ceramics with adhesive resin cements. These findings could assist dentists in reviewing and re-evaluating material choices in their clinical practices, both at a national and regional level. Additionally, the findings could be useful for dental policy makers, wholesale suppliers, and retail distributors in making future decisions. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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10 pages, 921 KiB  
Article
Influence of Time Interval, Temperature, and Storage Condition on Fluoride Release and Recharge from Silorane-Based Restorative Materials
by Prashanthi S. Madhyastha, Dilip G. Naik, Srikant Natarajan and Rachel Sarah Vinodhini
Dent. J. 2025, 13(5), 197; https://doi.org/10.3390/dj13050197 - 30 Apr 2025
Viewed by 393
Abstract
Objectives: The fluoride-releasing properties of restorative materials are crucial for the prevention of secondary caries as these can act as fluoride reservoirs. Hence, the present study aimed to investigate, assess, and compare the impact of time, temperature, and storage conditions on the fluoride [...] Read more.
Objectives: The fluoride-releasing properties of restorative materials are crucial for the prevention of secondary caries as these can act as fluoride reservoirs. Hence, the present study aimed to investigate, assess, and compare the impact of time, temperature, and storage conditions on the fluoride release of silorane-based composites (SBCs) and methacrylate-based composites (MBCs), and also evaluate the variation in their reuptake of fluoride (after recharge). Methods: SBC and MBC test samples of 10 mm × 2 mm dimensions were prepared and tested for fluoride release and recharge in distilled water and artificial saliva at temperatures of 4 °C, 37 °C, and 55 °C. The amount of fluoride released (at 1, 7, 14, and 28 days) and re-released after recharge (with 5000 ppm neutral sodium fluoride (NaF) solution for 5 min at 1, 3, and 7 days for 3 weeks) were studied with the help of a fluoride-selective ion electrode. Results: SBCs had a greater release of fluoride at low temperature in artificial saliva (0.07 ± 0.03) when compared to MBCs (0.04 ± 0.005). Fluoride release increased on day 7 but decreased over time (p < 0.05). Fluoride re-release was greater in MBCs than SBCs and it increased with time (p < 0.05). Conclusion: The amount of fluoride release and recharge depends on the time interval, temperature, and storage condition. These restorative materials can serve as fluoride reservoirs and contribute to sustained fluoride release in oral fluids, thereby preventing the initiation of secondary caries and the failure of restorations. In addition, it may assist in developing measures to improve fluoride delivery for topical applications. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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18 pages, 3340 KiB  
Article
Interfacial Effects Between Dental Impression and Die Materials and Their Role in the Internal Fit of Indirect Resin-Based Composite Restorations
by Murillo Weissheimer, João Carlos S. N. Foly, Fabíola G. Carvalho and Eliseu A. Münchow
Dent. J. 2025, 13(4), 155; https://doi.org/10.3390/dj13040155 - 31 Mar 2025
Viewed by 450
Abstract
Background/Objectives: This study tested a method for evaluating the internal fit of indirect resin-based composite (RBC) restorations, as well as the influence of different combinations of impression and die materials on the reproducibility of the topography of teeth prepared for indirect RBC restoration. [...] Read more.
Background/Objectives: This study tested a method for evaluating the internal fit of indirect resin-based composite (RBC) restorations, as well as the influence of different combinations of impression and die materials on the reproducibility of the topography of teeth prepared for indirect RBC restoration. Methods: Bovine incisors received flattened and cavitated areas at the cervical and middle thirds of the buccal surface, respectively. The samples were randomly assigned to two groups according to the material used for impression taking (n = 5): irreversible hydrocolloid and polyvinyl siloxane (PVS). Die replicas were obtained with Type IV gypsum or elastomeric material. RBC restorations were fabricated through an indirect technique (test) and a direct-indirect technique as the control. The internal fit of restorations was assessed by measuring the cementation line thickness with a digital caliper (simulated cementation protocol with ultra-light PVS) and validated using scanning electron microscopy (SEM). Surface topography (Sa, Sq, and Sz) was analyzed via optical profilometry, and wettability was assessed through the water contact angle method. The data were analyzed using t-test, ANOVA, and Pearson correlation tests (α = 5%). Results: The simulated cementation resulted in internal gap values positively correlated to the values from SEM (R2 = 0.958; p = 0.0102). The internal gap of restorations was not significantly correlated with the discrepancies between the topography of the die and tooth substrate (p ≥ 0.067). The combination of irreversible hydrocolloid and gypsum resulted in restorations with the lowest cementation line thickness, although in terms of roughness, this combination was the only one that resulted in significant differences from the control (p ≤ 0.028). The internal mean gap values of restorations were significantly correlated to the cumulative wettability difference of materials used during impression taking, fabrication of die replica, and restoration build-up (R2 = 0.981; p = 0.003). Conclusions: The reproducibility of topographical characteristics of the tooth in the die replica did not affect the internal adaptation of indirect RBC restorations, whereas surface wettability of materials presented a more relevant effect on the overall gap formation. The simulated cementation technique tested in the study shows potential as a simpler, cost-effective, and non-destructive method for evaluating the adaptation of indirect RBC restorations. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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16 pages, 10270 KiB  
Article
Does the Type of Resin Luting Material Affect the Bonding of CAD/CAM Materials to Dentin?
by Burcu Dikici, Elif Türkeş Başaran and Esra Can
Dent. J. 2025, 13(1), 41; https://doi.org/10.3390/dj13010041 - 19 Jan 2025
Cited by 3 | Viewed by 938
Abstract
Background/Objectives: This study aimed to investigate the microtensile bond strength (µTBS) of composite-based (Cerasmart), polymer-infiltrated (Vita Enamic), and feldspathic (Cerec) CAD/CAM blocks luted to dentin using a dual-cure resin cement (LinkForce), as well as micro-hybrid (G-aenial) and flowable composites (G-aenial Universal Flo), and [...] Read more.
Background/Objectives: This study aimed to investigate the microtensile bond strength (µTBS) of composite-based (Cerasmart), polymer-infiltrated (Vita Enamic), and feldspathic (Cerec) CAD/CAM blocks luted to dentin using a dual-cure resin cement (LinkForce), as well as micro-hybrid (G-aenial) and flowable composites (G-aenial Universal Flo), and evaluate the microhardness (HV) of luting materials through the CAD/CAM blocks. Methods: Cerasmart, Enamic, and Cerec were luted to dentin using three luting materials; LinkForce, G-aenial, and Universal Flo (n = 5). For HV, 117 disk-shaped specimens from LinkForce, G-aenial, and Universal Flo (n = 13) were polymerized through 3 mm thick CAD/CAM. Thirty-nine light-cured specimens without CAD/CAM were used as control. Following 24 h storage, the µTBS and HV were evaluated. Data were analyzed using the two-way ANOVA and post hoc Tukey tests (p < 0.05). Results: The µTBS to dentin and HV were significantly influenced by the type of luting material and CAD/CAM material. With all the CAD/CAM materials, LinkForce and Universal Flo exhibited a significantly similar µTBS to that of dentin (p > 0.05). Compared with the control group, all the HV values of the luting materials decreased significantly (p < 0.05). Conclusions: Heavily filled flowable composites exhibit a bonding effectiveness similar to that of dual-cure resin cements. All the luting materials showed similar HV when polymerized through the polymer-infiltrated CAD/CAM material. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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8 pages, 1452 KiB  
Article
The Flexural Strength and the Effect of the Autoclave Sterilization of Polypropylene/Natural Rubber Blended Materials
by Paphavarin Rangsantham, Thitaporn Nonthiphalang, Panjaporn Wongwitthayakool, Chakrit Sirisinha, Nantawan Krajangta and Panupat Phumpatrakom
Dent. J. 2024, 12(11), 361; https://doi.org/10.3390/dj12110361 - 13 Nov 2024
Cited by 3 | Viewed by 1573
Abstract
Background: Rubber dam clamps are used extensively in dentistry, especially during root canal treatment. However, existing rubber dam clamps have several drawbacks, including discomfort and potential damage to vital tissue in the oral cavity. To address these existing issues, a new rubber dam [...] Read more.
Background: Rubber dam clamps are used extensively in dentistry, especially during root canal treatment. However, existing rubber dam clamps have several drawbacks, including discomfort and potential damage to vital tissue in the oral cavity. To address these existing issues, a new rubber dam clamp should be developed. The aim of this study was to identify the optimum ratios of polypropylene and natural rubber (PP/NR) for a customized rubber dam clamp in dentistry. This study was focused on the flexural strength of PP/NR in various ratios. Moreover, the impact of autoclave sterilization was also considered. Methods: Six proportions of PP/NR blends (100/0, 90/10, 80/20, 70/30, 60/40 and 50/50) were prepared and assessed for flexural strength using a three-point bending test. After this test, the PP/NR blends with 100/0, 90/10 and 80/20 ratios were selected and underwent autoclave sterilization for 1, 5 and 10 cycles. Eventually, the flexural strength testing was repeated and investigated. An analysis of variance and Tukey’s test were used to evaluate the flexural strength of various PP/NR blends before autoclave sterilization at p < 0.05. An analysis of variance and Dunnett’s T3 test were used to evaluate the flexural strength of selected PP/NR blends before and after autoclave sterilization at p < 0.05. Results: The results revealed that the flexural strength of PP/NR blended materials showed a statistically significant difference in every group of this study. The autoclave sterilization test revealed that the flexural strength of the PP/NR 90/10 and 80/20 ratios was significantly increased after sterilization for 1, 5 and 10 cycles. In addition, the PP/NR 90/10 ratio was also comparable to the 100/0 ratio. The lower NR content in PP/NR blends resulted in significantly higher flexural strength, and autoclave sterilization had an effect on this property. Conclusions: This study suggested that the PP/NR blend with a 90/10 ratio might be considered as an alternative material for developing rubber dam clamps. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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14 pages, 4873 KiB  
Article
Primary Stability of Zirconia Dental Implants with Cylindrical and Tapered Designs Across Varying Bone Densities: An In Vitro Evaluation
by Diogo Fernandes, Francisco Cavaco, Filipe Freitas, Duarte Marques, João Caramês and André Moreira
Dent. J. 2024, 12(11), 356; https://doi.org/10.3390/dj12110356 - 5 Nov 2024
Viewed by 1426
Abstract
Background: While titanium implants are widely recognized for their clinical success, zirconia implants have emerged as a metal-free alternative. This study aimed to evaluate the influence of zirconia implant macrogeometry and bone density on primary implant stability. Methods: Two types of zirconia implants [...] Read more.
Background: While titanium implants are widely recognized for their clinical success, zirconia implants have emerged as a metal-free alternative. This study aimed to evaluate the influence of zirconia implant macrogeometry and bone density on primary implant stability. Methods: Two types of zirconia implants were tested—the Neodent® Zi Ceramic Implant and the Straumann® PURE Ceramic Implant, that were placed into polyurethane foam blocks mimicking different bone densities (10 PCF, 15 PCF, 20 PCF, 30 PCF, and 40 PCF). Each implant type was inserted and removed multiple times, with primary stability measured using resonance frequency analysis via the Osstell® Beacon device. Statistical tests, including the Shapiro–Wilk test, t-tests, the Mann–Whitney U test, and the Kruskal–Wallis test, were applied, with significance set at 5% (p < 0.05). Results: The tapered Neodent® Zi Ceramic Implant consistently showed higher ISQ values across all foam densities compared to the Straumann® PURE Ceramic Implant (p = 0.035). Additionally, lower-density foams exhibited lower stability scores (p < 0.05). Conclusion: The study concludes that both the macrogeometry of zirconia implants and bone density significantly affect primary implant stability. Specifically, tapered implants demonstrated higher stability than cylindrical designs, suggesting that implant macrogeometry and bone density should be considered for optimal primary stability in clinical settings. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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8 pages, 448 KiB  
Article
Color Stability of Bulk-Fill Flowable Resin Composites After Artificial Aging
by Franciele Floriani, Carlos A. Jurado, Nikkita Madhu, Mark A. Lackey, Francisco X. Azpiazu-Flores and Guilherme Carpena Lopes
Dent. J. 2024, 12(11), 350; https://doi.org/10.3390/dj12110350 - 31 Oct 2024
Cited by 1 | Viewed by 1474
Abstract
Background: This study aimed to evaluate the color stability of bulk-fill flowable resin composites with 2 difference shades at baseline and after artificial aging. Methods: Disk-shaped specimens (Ø10 × 4 mm) were fabricated from three bulk-fill flowable resin resin composites (Filtek Bulk-Fill Flow, [...] Read more.
Background: This study aimed to evaluate the color stability of bulk-fill flowable resin composites with 2 difference shades at baseline and after artificial aging. Methods: Disk-shaped specimens (Ø10 × 4 mm) were fabricated from three bulk-fill flowable resin resin composites (Filtek Bulk-Fill Flow, Venus Bulk-Fill Flow, and Estelite Bulk-Fill Flow). The specimens in each bulk-fill resin composite group were divided into two subgroups (n = 10 per subgroup) with two different shades, A1 (N = 30) and A3 (N = 30), and were polymerized with light curing (800 mW/cm2/Valo LED Unit, Ultradent) and polished. The color difference between bulk-fill resin composites was evaluated at baseline and after artificial aging using a spectrophotometer (CM-700d, Konica Minolta, Tokyo, Japan) under D65 illumination. Color coordinates were measured with CIEDE2000, and color differences (∆E00) and relative translucency parameter (RTP) values were calculated. Subsequently, the comparison of color changes (∆E00) before and after thermocycling was performed using the t-test for paired samples. Results: The bulk-fill flow resin composites evaluated in the present study were capable of mimicking important optical properties such as light transmission. All the resin composites provided acceptable color stability at baseline and after thermocycling when the color A1 was used. On the other hand, whenever the shade A3 was used, the Venus Bulk-Fill Flow demonstrated the best optical properties. There was no statistically significant difference when comparing baseline and after thermocycling in bulk-fill flowable resin composites (p > 0.05). After thermocycling, A1 bulk-fill flowable resin composites provided acceptable color stability, and all A3 bulk-fill flowable resin composites provided visible color change, except for the Venus Bulk-Fill Flow (∆E00 = 2.35). Conclusions: Estelite Bulk-Fill Flow displayed the best color stability (∆E00 = 2.22) between all the combinations evaluated. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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13 pages, 3919 KiB  
Article
Comparative Histological Analysis of Dentine-Derived Tooth Grafts in Maxillary vs Mandibular Socket Preservation: A Retrospective Study of 178 Cases
by Elio Minetti, Francesco Gianfreda, Patrizio Bollero, Ciro Annicchiarico, Monica Daniele, Rossella Padula and Filiberto Mastrangelo
Dent. J. 2024, 12(10), 320; https://doi.org/10.3390/dj12100320 - 7 Oct 2024
Cited by 3 | Viewed by 1569
Abstract
(1) Background: In recent years, there has been a growing interest in tooth-derived materials as valuable alternatives to synthetic biomaterials for preventing alveolar ridge dimensional changes. This study aimed to evaluate the histological and clinical differences between alveolar ridge preservation procedures in the [...] Read more.
(1) Background: In recent years, there has been a growing interest in tooth-derived materials as valuable alternatives to synthetic biomaterials for preventing alveolar ridge dimensional changes. This study aimed to evaluate the histological and clinical differences between alveolar ridge preservation procedures in the maxilla and mandible using demineralized dentin treated with Tooth Transformer®. (2) Methods: A total of 178 patients in good general health were enrolled, with 187 post-extractive sockets lacking buccal and/or palatal bone walls. Alveolar socket preservation procedures and histological evaluations were performed. The sites were divided into two groups: Group A (99 mandibular samples) and Group B (108 maxillary samples). After 5 months (±1 month), single bone biopsies were performed for histologic and histomorphometric analysis. (3) Results: Clinical outcomes demonstrated a good healing of hard and soft tissues with an effective maintenance of bone architecture in both groups. Histomorphometric analysis revealed a total bone volume of 50.33% (±14.86) in Group A compared to 43.53% (±12.73) in Group B. The vital new bone volume was 40.59% (±19.90) in Group A versus 29.70% (±17.68) in Group B, with residual graft dentin material volume at 7.95% (±9.85) in Group A compared to 6.75% (±9.62) in Group B. (4) Conclusions: These results indicate that tooth-derived material supports hard tissue reconstruction by following the structure of the surrounding bone tissue. A 6.8% difference observed between the maxilla and mandible reflects the inherent disparities in natural bone structures in these regions. This suggests that the bone regeneration process after tooth extraction adheres to an anatomical functional pattern that reflects the specific bone characteristics of each area, thus contributing to the preservation of the morphology and functionality of the surrounding bone tissue. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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12 pages, 4122 KiB  
Article
Comparison of Aesthetic, Mechanical Outcome, and Bone Loss in Angulated Screw Channels (ASCs) and Cement-Retained Implant-Supported Prosthesis: A Case-Control Study
by Edoardo Rella, Paolo De Angelis, Laura Papetti, Giovanni Damis, Giulio Gasparini, Antonio D’Addona and Paolo Francesco Manicone
Dent. J. 2024, 12(8), 233; https://doi.org/10.3390/dj12080233 - 24 Jul 2024
Cited by 1 | Viewed by 1579
Abstract
Angulated-screw channels (ASCs) allow the clinician to employ screw-retained restorations in almost all cases, as the access hole can be moved away from the vestibular portion of the crown, where it would jeopardize the final esthetic result. The objective of this study was [...] Read more.
Angulated-screw channels (ASCs) allow the clinician to employ screw-retained restorations in almost all cases, as the access hole can be moved away from the vestibular portion of the crown, where it would jeopardize the final esthetic result. The objective of this study was to compare screw-retained restorations employing ASCs with restorations cemented on angled abutments. In this study, 30 subjects, equally divided into two groups: group 1 (cemented restorations on angulated abutments) and group 2 (screw-retained restorations adopting ASCs), were treated and retrospectively compared after 2 years using the pink esthetic score (PES) and the white esthetic score (WES). All restorations were in use at the last follow-up, with a survival rate of 100%. Three mechanical complications were observed (2 chippings and 1 crown came loose), with a success rate of 93% in group 1 and 87% in group 2 (p > 0.05). No statistically significant differences were reported regarding the esthetic outcome; the marginal bone loss (MBL) showed better results for the screw-retained restorations, both at the distal aspect (group 1 = 0.98 mm ± 0.16; group 2 = 0.45 mm ± 0.06; p = 0.006) and at the mesial aspect (group 1 = 1.04 ± 0.27; group 2 = 0.45 ± 0.005; p < 0.001). From an esthetical perspective, screw-retained restorations with ASCs and cemented restorations on angulated abutments are both effective means of restoring implants; both have excellent esthetic outcomes, but screw-retained restorations have reduced bone loss when compared to cemented ones but are more prone to mechanical complications. Still, our results must be cautiously observed given the reduced dimension of our sample. Larger studies are needed to confirm our findings. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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14 pages, 6365 KiB  
Article
Use of Electropolishing in Orthodontic Appliances: An Option to Reduce the Risk of Metal Hypersensitivity
by Edith Lara-Carrillo, Ulises Velázquez-Enríquez, Brenda Andrea Ramírez-García, María Fernanda Lara-Fonseca, Raúl A. Morales-Luckie, Ana Miriam Santillán-Reyes, Victor Hugo Toral-Rizo, Elias Nahúm Salmerón-Valdés and Adriana Alejandra Morales-Valenzuela
Dent. J. 2024, 12(7), 193; https://doi.org/10.3390/dj12070193 - 24 Jun 2024
Viewed by 1305
Abstract
Electropolishing is a common treatment in the industry; however, how it behaves in the mouth and what benefits it can bring over metal dental attachments have not yet been established. Thus, the aim of this study was to determine the levels of corrosion, [...] Read more.
Electropolishing is a common treatment in the industry; however, how it behaves in the mouth and what benefits it can bring over metal dental attachments have not yet been established. Thus, the aim of this study was to determine the levels of corrosion, the released metal ions, and the changes in structural composition in metallic orthodontic appliances following electropolishing treatment. This study included 56 orthodontic brackets and 28 archwires. The samples were subjected to a pH cycle to simulate an oral environment. Using UV–Vis spectrophotometry, the release of metallic particles was evaluated, and using scanning electron microscopy, the structural and composition changes were evaluated. Groups were compared using Student’s t-tests with a value of p ≤ 0.05. The cyclical pH solutions showed variations between groups and days (1, 3, 5, 7 and 15), reaching the highest acidification in the self-ligating brackets; the absorbance between solutions did not differ significantly. As seen from the SEM results, the experimental group showed minor irregularities compared with the control groups. The experimental brackets decreased in iron and increased in chromium after electropolishing, while for the NiTi archwires, they decreased in nickel. Therefore, electropolishing treatments in metallic orthodontic attachments improve their surface structure and corrosion resistance could reduce the risk of metal hypersensitivity, mainly from nickel. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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12 pages, 2543 KiB  
Article
Impact of Scanbody Geometry and CAD Software on Determining 3D Implant Position
by Judith Kropfeld, Lara Berger, Werner Adler, Katja Leonie Schulz, Constantin Motel, Manfred Wichmann and Ragai Edward Matta
Dent. J. 2024, 12(4), 94; https://doi.org/10.3390/dj12040094 - 3 Apr 2024
Cited by 3 | Viewed by 2784
Abstract
The implementation of CAD software in the digital production of implant prosthetics stands as a pivotal aspect of clinical dentistry, necessitating high precision in the alignment of implant scanbodies. This study investigates the influence of scanbody geometry and the method of superimposing in [...] Read more.
The implementation of CAD software in the digital production of implant prosthetics stands as a pivotal aspect of clinical dentistry, necessitating high precision in the alignment of implant scanbodies. This study investigates the influence of scanbody geometry and the method of superimposing in CAD software when determining 3D implant position. A standardized titanium model with three bone-level implants was digitized to create reference STL files, and 10 intraoral scans were performed on Medentika and NT-Trading scanbodies. To determine implant position, the generated STL files were imported into the Exocad CAD software and superimposed—automatically and manually—with the scanbody geometries stored within the software’s shape library. Position accuracy was determined by a comparison of the 3D-defined scanbody points from the STL matching files with those from the reference STL files. The R statistical software was used for the evaluation of the data. In addition, mixed linear models and a significance level of 0.05 were applied to calculate the p-values. The manual overlay method was significantly more accurate than the automatic overlays for both scanbody types. The Medentika scanbodies showed slightly superior precision compared to the NT-Trading scanbodies. Both scanbody geometry and the type of alignment in the CAD software significantly affect digital workflow accuracy. Manual verification and adjustment of the automatic alignment process are essential for precise implant positioning. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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17 pages, 3848 KiB  
Article
In Vitro Risk Assessment of Dental Acid Erosion Caused by Long-Term Exposure to Oral Liquid Bandages
by Ryouichi Satou and Naoki Sugihara
Dent. J. 2024, 12(3), 70; https://doi.org/10.3390/dj12030070 - 6 Mar 2024
Viewed by 2510
Abstract
Oral mucosa inflammation can cause severe pain and interfere with eating, reducing quality of life. However, few options for self-care are available. An oral liquid bandage forms a protective film over the affected area. We aimed to assess the acid erosion risk when [...] Read more.
Oral mucosa inflammation can cause severe pain and interfere with eating, reducing quality of life. However, few options for self-care are available. An oral liquid bandage forms a protective film over the affected area. We aimed to assess the acid erosion risk when a newly developed oral liquid bandage (ORAPLA) is accidentally deposited on teeth and to examine the relative acid erosion risk at multiple time points of the maximum recommended duration of continuous use. ORAPLA was applied to both enamel and dentin blocks from 45 bovine anterior mandibular teeth, and an acid challenge was performed in a simulated oral cavity with artificial saliva, with one exposure cycle lasting 6 h. The enamel showed substantial defects and a decrease in Vickers hardness after nine cycles, with no change in surface roughness. Dentin showed an increase in parenchymal defects and surface roughness and a trend toward decreased Vickers hardness with increasing exposure time. We found no significant acid corrosion in enamel after up to nine times the upper limit of normal use time or in dentin after up to six times the upper limit. We conclude that the acid erosion risk due to accidental attachment to teeth is low, and in the human oral cavity with salivary buffering and remineralization, likely even lower. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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16 pages, 28168 KiB  
Article
Effect of Different Silane Coupling Agents on the Bond Strength between Hydrogen Peroxide-Etched Epoxy-Based- Fiber-Reinforced Post and Composite Resin Core
by Sarah Adwani, Emad Elsubeihi, Ahmad Zebari, May Aljanahi, Keyvan Moharamzadeh and Haitham Elbishari
Dent. J. 2023, 11(6), 142; https://doi.org/10.3390/dj11060142 - 29 May 2023
Cited by 4 | Viewed by 2939
Abstract
The aim of the study was to evaluate the effect of various silane coupling agents on the micro-push-out bond strength between a hydrogen peroxide-etched epoxy-based fiber-reinforced post and composite resin core. Seventy-five cross-linked epoxy-based fiber-reinforced posts were etched with 24% hydrogen peroxide for [...] Read more.
The aim of the study was to evaluate the effect of various silane coupling agents on the micro-push-out bond strength between a hydrogen peroxide-etched epoxy-based fiber-reinforced post and composite resin core. Seventy-five cross-linked epoxy-based fiber-reinforced posts were etched with 24% hydrogen peroxide for 10 min. Then they were divided into five groups according to various silane coupling agents and bonded to a composite core. A Universal Testing Machine was utilized to evaluate the push-out bond strength. In addition, all groups’ modes of failure were assessed. The push-out bond strength data in MPa were analyzed using ANOVA and a Tukey HSD post hoc test to reveal any difference between the groups. Results revealed that the application of a two-bottle silane coupling agent exhibited the highest bond strength, while the application of a one-bottle silane coupling agent demonstrated the lowest bond strength for a hydrogen peroxide-etched fiber post bonded to a composite core material, which was statistically significant (p < 0.05). The strongest association with the highest bond strength was found with the two-bottle silane coupling agent when compared to the one-bottle. The study highlighted that the application of a silane-coupling agent may affect the bond strength between composite and epoxy-based fiber-reinforced posts. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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14 pages, 2619 KiB  
Article
In Vitro Study of the Biological and Physical Properties of Dual-Cure Resin-Modified Calcium Silicate-Based Cement
by Minjung Kim, Sung-Hoon Lee and Dong-Hoon Shin
Dent. J. 2023, 11(5), 120; https://doi.org/10.3390/dj11050120 - 4 May 2023
Cited by 2 | Viewed by 2364
Abstract
Background: The aim of the present study was to compare the biological and mechanical properties of a novel dual-cure, resin-modified calcium silicate material, Theracal PT® (TP), with those of Theracal LC® (TL) and BiodentineTM (BD). Methods: The cell counting kit-8 [...] Read more.
Background: The aim of the present study was to compare the biological and mechanical properties of a novel dual-cure, resin-modified calcium silicate material, Theracal PT® (TP), with those of Theracal LC® (TL) and BiodentineTM (BD). Methods: The cell counting kit-8 was used on human dental pulp cells to test cell the viability of the three materials. Antibacterial activity of TP, TL, and BD against Enterococcus faecalis was investigated under anaerobic conditions. The ability of the materials to support odontogenic differentiation was studied by examining the relative gene expression of osteocalcin (OCN), osteopontin (OPN), and Collagen I (ColI) using real-time polymerase chain reaction. For mechanical property tests, microhardness was evaluated using the Vickers microhardness (VHN) test, and the bond strength to the resin was evaluated using a shear bond test machine. Results: There was no significant difference in cell viability between TL and TP after 48 h, and BD showed the highest cell viability, while TP showed the highest antibacterial effect. At the 12-h time point, there was no significant difference in ColI and OCN expression between BD and TP, but TP showed a higher expression of OPN than BD. However, at the 48-h time point, ColI and OCN showed higher levels of expression for BD than for TP and TL. At the same time point, only OPN had a higher diffusion for TP than for BD. TP demonstrated a VHN of approximately 30–35. This value was higher than that of TL and lower than that of BD. In contrast to VHN, the shear bond strength to resin was significantly higher for TL and TP than for BD. Conclusion: TP showed lower biocompatibility than BD but higher OPN expression and antibacterial effects than BD and TL. TP showed higher shear bond strength than BD and higher VHN than TL and BD at the 24-h time point. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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17 pages, 4476 KiB  
Article
Stamp Technique: An Explorative SEM Analysis
by Francesca Zotti, Stefano Vincenzi, Alessandro Zangani, Paolo Bernardi and Andrea Sbarbati
Dent. J. 2023, 11(3), 77; https://doi.org/10.3390/dj11030077 - 8 Mar 2023
Cited by 4 | Viewed by 7063
Abstract
Background: Achieving correct tooth anatomy and saving time at the dental chair are some of the goals of modern restorative dentistry. Stamp technique has gained acceptance in clinical practice. The aim of this study was to evaluate the effectiveness of this technique in [...] Read more.
Background: Achieving correct tooth anatomy and saving time at the dental chair are some of the goals of modern restorative dentistry. Stamp technique has gained acceptance in clinical practice. The aim of this study was to evaluate the effectiveness of this technique in terms of microleakage, voids, overhangs and marginal adaptation of Class I restorations, and to analyse the operative times in comparison with traditional restorative procedures. Methods: Twenty extracted teeth were divided into 2 groups. Ten teeth in the study group (SG) were Class I prepared and restored using stamp technique, and ten teeth in the control group (CG) were Class I restored traditionally. SEM analysis was performed to evaluate voids, microleakage, overhangs, and marginal adaptation, and operative times were recorded. A statistical analysis was performed. Results: There were no significant differences in microleakage, marginal adaptation and filling defects between the two groups, however, the stamp technique seems to facilitate the formation of large overflowing margins that require a careful finishing phase. Conclusions: Stamp technique does not seem to have any critical aspects in terms of restoration durability and it can be performed in a short time. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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Review

Jump to: Editorial, Research, Other

21 pages, 303 KiB  
Review
Cytotoxicity and Endocrine Disruption in Materials Used for Removable Orthodontic Retainers: A Comprehensive Review
by Katarzyna Chojnacka and Marcin Mikulewicz
Dent. J. 2025, 13(6), 269; https://doi.org/10.3390/dj13060269 - 17 Jun 2025
Viewed by 576
Abstract
Objective: To evaluate the cytotoxicity and endocrine-disrupting potential of materials used in removable orthodontic retainers. Methods: A literature search (2015–2025) covered in vitro cytotoxicity, estrogenicity, in vivo tissue responses, and clinical biomarkers in PMMA plates, thermoplastic foils, 3D-printed resins, PEEK, and fiber-reinforced composites. [...] Read more.
Objective: To evaluate the cytotoxicity and endocrine-disrupting potential of materials used in removable orthodontic retainers. Methods: A literature search (2015–2025) covered in vitro cytotoxicity, estrogenicity, in vivo tissue responses, and clinical biomarkers in PMMA plates, thermoplastic foils, 3D-printed resins, PEEK, and fiber-reinforced composites. Results: Thirty-eight in vitro and ten clinical studies met inclusion criteria, identified via a structured literature search of electronic databases (2015–2025). Photopolymer resins demonstrated the highest cytotoxicity, whereas thermoplastics and PMMA exhibited predominantly mild effects, which diminished further following 24 h water storage. Bisphenol-type compound release was reported, but systemic exposure remained below regulatory limits. No statistically significant mucosal alterations or endocrine-related effects were reported in clinical studies. Conclusions: Retainer materials are generally biocompatible, though data on long-term endocrine effects are limited. Standardized biocompatibility assessment protocols are necessary to enable comparative evaluation across diverse orthodontic materials. Single-use thermoplastics contribute to microplastic release and pose end-of-life management challenges, raising concerns regarding environmental sustainability. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
24 pages, 2803 KiB  
Review
Dental Applications of Ion-Substituted Hydroxyapatite: A Review of the Literature
by Eisha Imran, May L. Mei, Kai Chun Li, Jithendra Ratnayake, Manikandan Ekambaram and Paul R. Cooper
Dent. J. 2024, 12(10), 304; https://doi.org/10.3390/dj12100304 - 25 Sep 2024
Cited by 5 | Viewed by 2836
Abstract
Hydroxyapatite (HA) forms an essential constituent of human teeth and bone. Its distinctive characteristic features, such as bioactivity and osteoconductivity, make it an ideal candidate to be used as an implant coating in restorative dentistry and maxillofacial surgery for bone regeneration. However, low [...] Read more.
Hydroxyapatite (HA) forms an essential constituent of human teeth and bone. Its distinctive characteristic features, such as bioactivity and osteoconductivity, make it an ideal candidate to be used as an implant coating in restorative dentistry and maxillofacial surgery for bone regeneration. However, low fracture toughness and brittleness are a few of the inherent features of HA, which limit its application in load-bearing areas. The potential of HA to engage its lattice structure with either partial or complete substitution with external ions has become an increasing area of research as this phenomenon has the potential to enhance the biological and functional properties of the material. Consequently, this review aimed to highlight the role of various substituted ions in dental applications. Data indicate that the newly formed HA-substituted biomaterials demonstrate enhanced remineralization and antimicrobial activity along with improved hardness. Ion-substituted HA offers a promising strategy for future clinical research as these materials may be incorporated into various dental products for therapeutic treatments. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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Other

20 pages, 702 KiB  
Systematic Review
The Effectiveness and Complication Rate of Resorbable Biopolymers in Oral Surgery: A Systematic Review
by Riccardo Fabozzi, Francesco Bianchetti, Domenico Baldi, Catherine Yumang Sanchez, Francesco Bagnasco and Nicola De Angelis
Dent. J. 2025, 13(6), 264; https://doi.org/10.3390/dj13060264 - 13 Jun 2025
Cited by 1 | Viewed by 870
Abstract
Background: Resorbable biopolymers are increasingly explored for use in regenerative procedures within dental surgery. Their ability to degrade naturally, minimize surgical reinterventions, and potentially reduce immunogenicity makes them appealing in guided bone and tissue regeneration applications. However, despite these advantages, uncertainties persist [...] Read more.
Background: Resorbable biopolymers are increasingly explored for use in regenerative procedures within dental surgery. Their ability to degrade naturally, minimize surgical reinterventions, and potentially reduce immunogenicity makes them appealing in guided bone and tissue regeneration applications. However, despite these advantages, uncertainties persist regarding their comparative effectiveness and associated risks. For example, polyethylene glycol (PEG)-based membranes have shown comparable outcomes to porcine-derived collagen membranes in bone regeneration procedures, yet studies have reported a higher incidence of soft tissue healing complications associated with PEG-based materials. Similarly, while polycaprolactone (PCL) and dextrin-based hydrogels have demonstrated promising clinical handling and bone fill capabilities, their long-term performance and consistency across different anatomical sites remain under investigation. These findings highlight the need for further well-powered clinical trials to establish standardized guidelines for their safe and effective use. Methods: A systematic review protocol was registered with the PROSPERO database and developed in alignment with PRISMA guidelines. Database searches were conducted in PubMed, Medline, Scopus, and Cochrane from June to December 2024. Only randomized controlled trials (RCTs) focusing on synthetic resorbable biopolymers in bone augmentation procedures were considered. Bias was evaluated using the Cochrane Risk of Bias tool. Results: Eleven RCTs were included, totaling 188 patients. The findings suggest that materials such as polylactic acid (PLA), polycaprolactone (PCL), and polyethylene glycol (PEG) contributed effectively to new bone formation. PEG-based membranes were found to perform on par with or occasionally better than traditional collagen membranes derived from porcine sources. Additionally, the application of 3D-printable polymers demonstrated promise in site-specific healing. Conclusions: Resorbable biopolymers are effective and safe for GBR procedures, with clinical outcomes comparable to traditional materials. Advances in 3D-printing technology and bioactive coatings may further enhance their regenerative potential. However, the incidence of soft tissue healing complications suggests the need for further long-term studies to optimize material properties and clinical application. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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25 pages, 709 KiB  
Systematic Review
The Fracture Resistance Comparison between Titanium and Zirconia Implant Abutments with and without Ageing: Systematic Review and Meta-Analysis
by Marek Chmielewski, Wojciech Dąbrowski and Iwona Ordyniec-Kwaśnica
Dent. J. 2024, 12(9), 274; https://doi.org/10.3390/dj12090274 - 23 Aug 2024
Cited by 2 | Viewed by 2091
Abstract
Implant abutments are essential components of implant prosthetic restorations. The golden standard for abutment material is titanium; however, due to its properties, the esthetic result can be compromised. The most popular esthetic material alternatives are one- and two-piece zirconia. The study aimed to [...] Read more.
Implant abutments are essential components of implant prosthetic restorations. The golden standard for abutment material is titanium; however, due to its properties, the esthetic result can be compromised. The most popular esthetic material alternatives are one- and two-piece zirconia. The study aimed to answer the questions of whether zirconia abutments can be used interchangeably with titanium in both anterior and posterior regions and how aging of the abutment affects durability. For this study, an electronic search of MEDLINE (PubMed) and Scopus (Embase) was conducted. The PRISMA guidelines were followed, and a systematic review was registered with PROSPERO. The search revealed 4031 results, of which 17 studies were selected. The strongest material for abutments is titanium, closely followed by two-piece zirconia. One-piece zirconia abutments were the weakest. The cyclic loading above 1,000,000 cycles decreased the fracture resistance of the abutments. Differences in implant diameter, angulation, and restoration affected the fracture strength of all compared materials. The main mode of failure for titanium abutments was screw bending or screw fracture. One-piece zirconia most often presented catastrophic failure with internal hexagon fracture below the implant neck. Two-piece zirconia exhibits a combination of failure modes. Two-piece zirconia abutments may be suitable for use in the posterior region, given their comparable fracture resistance to titanium abutments. Despite the fact that one-piece zirconia is capable of withstanding forces that exceed those exerted during mastication, it is recommended that it be employed primarily in the anterior dentition due to its propensity for unfavorable failure modes. Full article
(This article belongs to the Special Issue Dental Materials Design and Innovative Treatment Approach)
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