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29,642 Results Found

  • Review
  • Open Access
96 Citations
11,281 Views
16 Pages

Angiotensin-Converting Enzymes Play a Dominant Role in Fertility

  • Pei-Pei Pan,
  • Qi-Tao Zhan,
  • Fang Le,
  • Ying-Ming Zheng and
  • Fan Jin

21 October 2013

According to the World Health Organization, infertility, associated with metabolic syndrome, has become a global issue with a 10%–20% incidence worldwide. An accumulating body of evidence has shown that the renin–angiotensin system is involved in th...

  • Article
  • Open Access
10 Citations
2,851 Views
14 Pages

9 March 2021

In recent years, two dimensional (2D) hydraulic components have significantly flourished. After a brief development introduction of the 2D pump and 2D flowmeter, it could be concluded that the churning loss, which is caused by the rotational motion o...

  • Article
  • Open Access
4 Citations
2,078 Views
14 Pages

Phase Transformation of Arsenic, Antimony and Lead in High-Grade Copper Matte Converting

  • Wenkai Qu,
  • Yingbao Yang,
  • Shiwei Zhou,
  • Yonggang Wei and
  • Bo Li

9 May 2024

The duration of the high-grade matte converting process is short, the amount of slag is small, and it is difficult for the original impurity removal operation in the low-grade matte converting process to meet the current production demand. Because th...

  • Article
  • Open Access
1 Citations
4,568 Views
14 Pages

5 September 2023

This article examines the historical background of “Laozi huahu 老子化胡” (Laozi converting the barbarians) and investigates its generation mode and constituent elements. It also discusses and reflects on issues su...

  • Article
  • Open Access
1,406 Views
25 Pages

Industrial Implementation of Digital Twin in the Tissue Paper Converting System

  • Haoliang Cui,
  • Xiansheng Guo,
  • Mohan Wang,
  • Dedong Zhang,
  • Jiwei Zhang,
  • Yun Zhang,
  • Feng Gu and
  • Shaozhang Niu

26 March 2025

The tissue paper converting system involves critical stages, including unwinding, embossing, folding, stacking, cutting, and packaging. Despite its maturity, challenges such as production interruptions during roll changes, equipment coordination issu...

  • Article
  • Open Access
2 Citations
2,217 Views
16 Pages

Learning and Investigation of the Role of Angiotensin-Converting Enzyme in Radiotherapy for Nasopharyngeal Carcinoma

  • Yanan Ding,
  • Huanhuan Xiu,
  • Yanling Zhang,
  • Miaola Ke,
  • Letao Lin,
  • Huzheng Yan,
  • Pan Hu,
  • Meigui Xiao,
  • Xu He and
  • Tao Zhang

Ionizing radiation (IR) is an important treatment for nasopharyngeal carcinoma (NPC) that mainly kills tumor cells by producing large amounts of reactive oxygen species (ROS). Intracellular ROS levels affect the sensitivity of tumor cells to IR. Rece...

  • Review
  • Open Access
339 Citations
18,291 Views
19 Pages

Angiotensin-I-Converting Enzyme (ACE)-Inhibitory Peptides from Plants

  • Ceren Daskaya-Dikmen,
  • Aysun Yucetepe,
  • Funda Karbancioglu-Guler,
  • Hayrettin Daskaya and
  • Beraat Ozcelik

23 March 2017

Hypertension is an important factor in cardiovascular diseases. Angiotensin-I-converting enzyme (ACE) inhibitors like synthetic drugs are widely used to control hypertension. ACE-inhibitory peptides from food origins could be a good alternative to sy...

  • Review
  • Open Access
334 Citations
20,885 Views
14 Pages

31 March 2010

Hypertension or high blood pressure is one of the major independent risk factors for cardiovascular diseases. Angiotensin-I-converting enzyme (EC 3.4.15.1; ACE) plays an important physiological role in regulation of blood pressure by converting angio...

  • Article
  • Open Access
17 Citations
4,882 Views
12 Pages

An Impact-Based Frequency Up-Converting Hybrid Vibration Energy Harvester for Low Frequency Application

  • Zhenlong Xu,
  • Wen Wang,
  • Jin Xie,
  • Zhonggui Xu,
  • Maoying Zhou and
  • Hong Yang

2 November 2017

In this paper, a novel impact-based frequency up-converting hybrid energy harvester (FUCHEH) was proposed. It consisted of a piezoelectric cantilever beam and a driving beam with a magnetic tip mass. A solenoid coil was attached at the end of the pie...

  • Review
  • Open Access
2 Citations
2,869 Views
22 Pages

Radiotracers for Molecular Imaging of Angiotensin-Converting Enzyme 2

  • Wenqi Xu,
  • Sigrid A. Langhans,
  • David K. Johnson,
  • Erik Stauff,
  • Vinay V. R. Kandula,
  • Heidi H. Kecskemethy,
  • Lauren W. Averill and
  • Xuyi Yue

30 August 2024

Angiotensin-converting enzymes (ACE) are well-known for their roles in both blood pressure regulation via the renin-angiotensin system as well as functions in fertility, immunity, hematopoiesis, and many others. The two main isoforms of ACE include A...

  • Article
  • Open Access
2 Citations
3,574 Views
10 Pages

15 January 2020

We propose a ring oscillator (RO) based current-to-voltage-to-frequency (I–V–F) converting current transducer with a cascade bias circuit. The I–V–F converting scheme guarantees highly stable biasing against RO, with a rail-to...

  • Article
  • Open Access
35 Citations
5,168 Views
14 Pages

31 October 2019

The bioactivity of ten traditional Korean Angelica species were screened by angiotensin-converting enzyme (ACE) assay in vitro. Among the crude extracts, the methanol extract of Angelica decursiva whole plants exhibited potent inhibitory effects agai...

  • Article
  • Open Access
2 Citations
2,311 Views
21 Pages

Proteomic Analysis of Human Macrophages Overexpressing Angiotensin-Converting Enzyme

  • Delia Oosthuizen,
  • Tariq A. Ganief,
  • Kenneth E. Bernstein and
  • Edward D. Sturrock

Angiotensin converting enzyme (ACE) exerts strong modulation of myeloid cell function independently of its cardiovascular arm. The success of the ACE-overexpressing murine macrophage model, ACE 10/10, in treating microbial infections and cancer opens...

  • Review
  • Open Access
52 Citations
9,258 Views
19 Pages

11 January 2020

The angiotensin-converting enzyme (ACE) is a two-domain dipeptidylcarboxypeptidase, which has a direct involvement in the control of blood pressure by performing the hydrolysis of angiotensin I to produce angiotensin II. At the same time, ACE hydroly...

  • Article
  • Open Access
3 Citations
3,041 Views
13 Pages

24 June 2020

This experimental study investigates the effects of the aggregate surface conditions on the compressive strength of quick-converting track concrete (QTC). The compressive strength of QTC and interfacial fracture toughness (IFT) were investigated by c...

  • Review
  • Open Access
36 Citations
9,825 Views
10 Pages

7 December 2021

A 2018 report from the American Heart Association shows that over 103 million American adults have hypertension. The angiotensin-converting enzyme (ACE) (EC 3.4.15.1) is a dipeptidyl carboxylase that, when inhibited, can reduce blood pressure through...

  • Article
  • Open Access
12 Citations
5,129 Views
21 Pages

This study is focused on the wave energy converter of an oscillating water column (OWC) system that is integrated with a jacket type infrastructure applied for an offshore wind turbine system. In this way, electricity generation by both wind power an...

  • Article
  • Open Access
13 Citations
4,338 Views
12 Pages

12 March 2020

The inhibition of human angiotensin I converting enzyme (ACE) has been regarded as a promising approach for the treatment of hypertension. Despite research attempts over many years, our understanding the mechanisms of activation and inhibition of ACE...

  • Article
  • Open Access
2 Citations
4,404 Views
9 Pages

Angiotensin-Converting Enzyme Activity May Predict Disease Severity in Psoriasis

  • Matilde Bandeira,
  • Ângela Gil,
  • Ana Carolina Santos,
  • Vasco C. Romão,
  • Mário Rui Mascarenhas,
  • Paulo Filipe,
  • João Eurico Fonseca and
  • Manuel Bicho

14 February 2022

Psoriasis is a multifactorial disease, with many genetic risk factors, one of which seems to be the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism. ACE activity has been shown to be higher in psoriatic patients and it sugge...

  • Article
  • Open Access
15 Citations
4,811 Views
16 Pages

Crushing of Single-Walled Corrugated Board during Converting: Experimental and Numerical Study

  • Tomasz Garbowski,
  • Tomasz Gajewski,
  • Damian Mrówczyński and
  • Radosław Jędrzejczak

30 May 2021

Corrugated cardboard is an ecological material, mainly because, in addition to virgin cellulose fibers also the fibers recovered during recycling process are used in its production. However, the use of recycled fibers causes slight deterioration of t...

  • Article
  • Open Access
4 Citations
1,949 Views
17 Pages

Investigation of the Interaction Between Angiotensin-Converting Enzyme (ACE) and ACE-Inhibitory Tripeptide from Casein

  • Cuicui Yang,
  • Tianzhao Xie,
  • Mengmeng Cai,
  • Xiaoting Xu,
  • Muzijun Li,
  • Pengru Liu and
  • Xiongdiao Lan

4 December 2024

Angiotensin-converting enzyme (ACE) inhibitory peptides exhibit antihypertensive effects by inhibiting ACE activity, and the study of the interaction between ACEs and inhibitory peptides is important for exploring new therapeutic strategies. In this...

  • Article
  • Open Access
3 Citations
3,251 Views
22 Pages

21 February 2022

This study is an experimental study corresponding to an analytical study presented previously, where a scaled-down model was built and tested in a water tank by following the size and shape of the structure applied in the analytical study. In this st...

  • Article
  • Open Access
3 Citations
1,807 Views
15 Pages

18 August 2022

In this paper, we consider a two-stage converting-converting (CC) switching network. This structure can be used, for instance, in switches of elastic optical networks (EONs) or in time-division switches. We propose a new routing algorithm based on fi...

  • Article
  • Open Access
1 Citations
2,395 Views
19 Pages

New Class of Power Converter for Performing the Multiple Operations in a Single Converter: Universal Power Converter

  • Dhananjaya Mudadla,
  • Devendra Potnuru,
  • Raavi Satish,
  • Almoataz Y. Abdelaziz and
  • Adel El-Shahat

29 August 2022

Universal power converters (UPCs) have aroused significant attention in performing multiple operations in a single power converter. Furthermore, they contribute to economic operation and improved system performance. In this work, a new configuration...

  • Article
  • Open Access
1 Citations
1,944 Views
25 Pages

Rabbit and Human Angiotensin-Converting Enzyme-2: Structure and Electric Properties

  • Svetlana H. Hristova,
  • Trifon T. Popov and
  • Alexandar M. Zhivkov

19 November 2024

The angiotensin-converting enzyme-2 (ACE2) is a transmembrane glycoprotein, consisting of two segments: a large carboxypeptidase catalytic domain and a small transmembrane collectrin-like segment. This protein plays an essential role in blood pressur...

  • Article
  • Open Access
6 Citations
3,119 Views
25 Pages

23 June 2022

The topological cues of fibrous scaffolds (in particular extracellular matrix (ECM)-mimetic nanofibers) have already proven to be a powerful tool for influencing neuronal morphology and behavior. Remote photothermal optical treatment provides additio...

  • Communication
  • Open Access
371 Views
9 Pages

3 January 2026

Amaranth 11S globulin is a plant protein that is renowned for its high essential amino acid content and nutritional value. It has undergone modification through the insertion of antihypertensive peptides valine-tyrosine (VY), which act as angiotensin...

  • Article
  • Open Access
60 Citations
6,809 Views
8 Pages

27 September 2018

Angiotensin I-converting enzyme (ACE) peptides are bioactive peptides that have important value in terms of research and application in the prevention and treatment of hypertension. While widespread literature is concentrated on casein or whey protei...

  • Article
  • Open Access
1 Citations
1,922 Views
18 Pages

Myocardial Angiotensin-Converting Enzyme 2 Protein Expression in Ischemic Heart Failure

  • Vitalija Siratavičiūtė,
  • Dalia Pangonytė,
  • Lina Utkienė,
  • Lina Jusienė,
  • Jolanta Marcinkevičienė,
  • Zita Stanionienė and
  • Reda Radikė

5 December 2023

The angiotensin-converting enzyme 2 (ACE2)-angiotensin-(1-7)-Mas receptor axis plays a significant role in regulating myocardial remodeling and the development of heart failure (HF), with ACE2 being the primary focus. However, contemporary understand...

  • Review
  • Open Access
10 Citations
4,026 Views
18 Pages

Angiotensin-Converting Enzyme 2 Expression and Severity of SARS-CoV-2 Infection

  • Sarah Alabsi,
  • Atharva Dhole,
  • Sameh Hozayen and
  • Scott A. Chapman

Angiotensin-converting enzyme 2 (ACE2), first discovered in 2000, serves as an important counterregulatory enzyme to the angiotensin II-mediated vasoconstrictive, pro-inflammatory, and pro-fibrotic actions of the renin–angiotensin system (RAS)....

  • Article
  • Open Access
19 Citations
4,515 Views
14 Pages

Isolation, Evaluation, and Identification of Angiotensin I-Converting Enzyme Inhibitory Peptides from Game Meat

  • Shiro Takeda,
  • Sakurako Kaneko,
  • Kazuyuki Sogawa,
  • Abdulatef M Ahhmed,
  • Hirofumi Enomoto,
  • Shinpei Kawarai,
  • Kensuke Taira,
  • Wataru Mizunoya,
  • Masato Minami and
  • Ryoichi Sakata

25 August 2020

Game meat has been underutilized, while it offers the potential to diversify not only the human diet but also increase food production and the nutritional value of meat products. This study aimed to determine the angiotensin I-converting enzyme (ACE)...

  • Article
  • Open Access
3 Citations
2,186 Views
18 Pages

Control and Optimization of Lattice Converters

  • Zhiting Mei,
  • Jingyang Fang and
  • Stefan Goetz

15 February 2022

Multilevel converters continue their upward trend in renewable generation, electric vehicles, and power quality conditioning applications. Despite having satisfactory voltage capabilities, mainstream multilevel converters suffer from poor current sha...

  • Article
  • Open Access
2 Citations
3,213 Views
13 Pages

OLEDs on Down-Converting Fabric by Using a High Scalable Planarization Process and a Transparent Polymeric Electrode

  • Carmela Tania Prontera,
  • Marco Pugliese,
  • Fabrizio Mariano,
  • Daniela Taurino,
  • Roberto Giannuzzi,
  • Vitantonio Primiceri,
  • Marco Esposito,
  • Antonio Andretta,
  • Giuseppe Gigli and
  • Vincenzo Maiorano

15 February 2024

Textile-based electronics represents a key technology for the development of wearable devices. Light-emitting textiles based on OLED architecture are particularly promising due to their intrinsic flexibility and possibility to be fabricated on large...

  • Article
  • Open Access
16 Citations
4,673 Views
13 Pages

9 November 2018

Angiotensin-converting enzymes, ACE and ACE2, are two main elements in the renin–angiotensin system, with a crucial role in the regulation of blood pressure in vertebrates. Previous studies paid much attention to their physiological functions i...

  • Article
  • Open Access
4 Citations
3,155 Views
20 Pages

New Insights on Glutathione’s Supramolecular Arrangement and Its In Silico Analysis as an Angiotensin-Converting Enzyme Inhibitor

  • Antônio S. N. Aguiar,
  • Igor D. Borges,
  • Leonardo L. Borges,
  • Lucas D. Dias,
  • Ademir J. Camargo,
  • Pál Perjesi and
  • Hamilton B. Napolitano

17 November 2022

Angiotensin-converting enzyme (ACE) inhibitors are one of the most active classes for cardiovascular diseases and hypertension treatment. In this regard, developing active and non-toxic ACE inhibitors is still a continuous challenge. Furthermore, the...

  • Review
  • Open Access
2 Citations
3,794 Views
14 Pages

10 March 2024

Angiotensin-converting enzyme (ACE) inhibitors are used primarily in the treatment of hypertension, heart failure, and in the acute phase of myocardial infarction. Lisinopril [N2-[(1S)-1-car-boxy-3-phenylpropyl]-L-lysyl-L-proline], enalapril [(S)-1-[...

  • Article
  • Open Access
24 Citations
3,872 Views
13 Pages

Levels of Angiotensin-Converting Enzyme and Apolipoproteins Are Associated with Alzheimer’s Disease and Cardiovascular Diseases

  • Chun Xu,
  • Debra Garcia,
  • Yongke Lu,
  • Kaysie Ozuna,
  • Donald A. Adjeroh,
  • Kesheng Wang and
  • on behalf of the Alzheimer’s Disease Neuroimaging Initiative

23 December 2021

Angiotensin-converting enzyme-1 (ACE1) and apolipoproteins (APOs) may play important roles in the development of Alzheimer’s disease (AD) and cardiovascular diseases (CVDs). This study aimed to examine the associations of AD, CVD, and endocrine...

  • Review
  • Open Access
8 Citations
3,253 Views
25 Pages

The Impact of Angiotensin-Converting Enzyme-2/Angiotensin 1-7 Axis in Establishing Severe COVID-19 Consequences

  • Minela Aida Maranduca,
  • Daniela Maria Tanase,
  • Cristian Tudor Cozma,
  • Nicoleta Dima,
  • Andreea Clim,
  • Alin Constantin Pinzariu,
  • Dragomir Nicolae Serban and
  • Ionela Lacramioara Serban

The COVID-19 pandemic has put a tremendous stress on the medical community over the last two years. Managing the infection proved a lot more difficult after several research communities started to recognize the long-term effects of this disease. The...

  • Article
  • Open Access
8 Citations
6,204 Views
12 Pages

In Vivo Diuretic Activity and Anti-Hypertensive Potential of Hibiscus sabdariffa Extract by Inhibition of Angiotensin-Converting Enzyme and Hypertension Precursor Enzymes

  • Abdoudramane Sanou,
  • Kiessoun Konaté,
  • Lazare Belemnaba,
  • Hemayoro Sama,
  • Kabakdé Kaboré,
  • Roger Dakuyo,
  • Mathieu Nitiéma and
  • Mamoudou Hama Dicko

9 February 2024

Aqueous extracts of calyx from Hibiscus sabdariffa (HS) (roselle) are highly appreciated for their nutritional and therapeutic effects, especially as anti-hypertensive substances. This study aimed to evaluate their anti-hypertensive potential through...

  • Review
  • Open Access
11 Citations
6,821 Views
9 Pages

9 October 2012

Angiotensin II is a key regulator of blood pressure and cardiovascular function in mammals. The conversion of angiotensin into its active form is carried out by Angiotensin I-Converting Enzyme (ACE). The measurement of ACE concentration in plasma or...

  • Article
  • Open Access
73 Citations
5,797 Views
14 Pages

Protein Expression of Angiotensin-Converting Enzyme 2 (ACE2) is Upregulated in Brains with Alzheimer’s Disease

  • Qiyue Ding,
  • Nataliia V. Shults,
  • Sergiy G. Gychka,
  • Brent T. Harris and
  • Yuichiro J. Suzuki

8 February 2021

Alzheimer’s disease is a chronic neurodegenerative disorder and represents the main cause of dementia globally. Currently, the world is suffering from the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coron...

  • Article
  • Open Access
1 Citations
1,468 Views
8 Pages

Eye Washing Downregulated Angiotensin-Converting Enzyme 2 in Conjunctival Tissue Samples from Smokers

  • Hiroshi Fujishima,
  • Hiroyuki Yazu,
  • Eisuke Shimizu,
  • Naoko Okada and
  • Kazumi Fukagawa

15 December 2023

This study aimed to (1) determine whether the expression of angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 is increased in tobacco smokers, which potentially increases their susceptibility to severe acute respiratory syndr...

  • Article
  • Open Access
1 Citations
1,773 Views
12 Pages

Effects of Angiotensin-Converting Enzyme Inhibition on the Recurrence and Internal Structure of Chronic Subdural Hematomas

  • Michael Veldeman,
  • Hani Ridwan,
  • Mohamed Alzaiyani,
  • Rastislav Pjontek,
  • Benedikt Kremer,
  • Anke Hoellig,
  • Hans Clusmann and
  • Hussam Hamou

6 August 2024

Background/Objectives: Chronic subdural hematoma (cSDH) is a common disease of growing significance due to the increasing use of antithrombotic drugs and population aging. There exists conflicting observational evidence that previous treatment with a...

  • Article
  • Open Access
5 Citations
2,549 Views
21 Pages

27 April 2023

It is of extreme importance to develop a reliable numerical prediction technique to simulate the ballistic response of ceramic armor subjected to high-velocity impact (HVI) to economize the test cost and shorten the design period. In the present manu...

  • Article
  • Open Access
40 Citations
3,650 Views
18 Pages

Design and Implementation a Single-Switch Step-Up DC-DC Converter Based on Cascaded Boost and Luo Converters

  • Hossein Gholizadeh,
  • Reza Sharifi Shahrivar,
  • Mir Reza Hashemi,
  • Ebrahim Afjei and
  • Saman A. Gorji

16 June 2021

We designed and implemented a single-switch step-up DC-DC converter based on cascaded boost and Luo converters. The proposed converter demonstrated a quadratic voltage gain and a high efficiency, which makes it suitable for renewable energy applicati...

  • Review
  • Open Access
3 Citations
2,884 Views
17 Pages

15 August 2023

Power converter technologies have become vital in various applications due to their efficient management of electrical energy. With the growing prominence of renewable energy sources such as solar and wind, the high penetration of power electronic co...

  • Article
  • Open Access
4 Citations
5,229 Views
13 Pages

Impedance-Source DC-to-AC/DC Converter

  • Rajendran Sivapriyan and
  • Devaraj Elangovan

This article presents a novel impedance-source-based direct current (DC)-to-alternating current (AC)/DC converter (Z-Source DAD Converter). The Z-Source DAD converter converts the input DC voltage into AC or DC with buck or boost in the load voltage....

  • Review
  • Open Access
16 Citations
6,826 Views
16 Pages

A Review of Hybrid Converter Topologies

  • Hossein Afshari,
  • Oleksandr Husev,
  • Oleksandr Matiushkin and
  • Dmitri Vinnikov

9 December 2022

There is a growing interest in solar energy systems with storage battery assistance. There is a corresponding growing interest in hybrid converters. This paper provides a comprehensive review of hybrid converter topologies. The concept of a hybrid in...

  • Article
  • Open Access
4 Citations
2,852 Views
18 Pages

A Critical Comparison of the Cuk and the Sheppard–Taylor Converter

  • Alfredo Alvarez-Diazcomas,
  • Juvenal Rodríguez-Reséndiz,
  • Roberto V. Carrillo-Serrano,
  • Adyr A. Estévez-Bén and
  • José Manuel Álvarez-Alvarado

The use of and interest in renewable energy have increased in recent years due to the environmental impact of the technologies currently used to generate electricity. Switched converters play a fundamental role in renewable energy systems. The main g...

  • Feature Paper
  • Review
  • Open Access
27 Citations
11,600 Views
20 Pages

Voltage step-down converters have gained attention, with the rapid development in industrial robotics, Internet of things, and embedded system applications. Therefore, a comprehensive analysis has been performed, to identify the topologies and archit...

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