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  • Article
  • Open Access
7 Citations
19,629 Views
15 Pages

23 February 2025

Background: The prolonged use of smartphones may lead to cervical posture deformities and other associated issues. Among these conditions, cervical extension type is one of the most commonly observed, characterized by increased cervical lordosis, for...

(This article belongs to the Special Issue Advances in Sports, Exercise and Health)
  • Article
  • Open Access
1,027 Views
14 Pages

18 June 2026

Background: Cervical extension type is commonly associated with forward head posture and altered cervical and scapular muscle activity. However, the comparative effects of cervical stabilization exercises combined with scapular stabilization exercise...

(This article belongs to the Section Applied Biosciences and Bioengineering)
  • Article
  • Open Access
2 Citations
712 Views
6 Pages

Conservative Surgical Treatment in Cervical Dysplastic Lesions Associated with Cystorectocele

  • Bogdan Marian Puca,
  • Anca Daniela Braila,
  • Cosmin Vasile Obleaga,
  • Mihai Braila and ,
  • Hany Saad,
  • Cristian Lungulescu and
  • Mihai Deca
  • + 2 authors+ 0 author

The treatment of cervical intraepithelial neoplasia aims at removing the squamocolumnar junction area, including abnormal tissues, up to the healthy tissue. Old postpartum perineal tears associated with cystorectocele, hypertrophic cervical elongatio...

  • Article
  • Open Access
6 Citations
5,026 Views
12 Pages

Association between Occupation and Cervical Disc Degeneration in 1211 Asymptomatic Subjects

  • Masaaki Machino,
  • Hiroaki Nakashima,
  • Keigo Ito,
  • Kei Ando and ,
  • Sadayuki Ito,
  • Fumihiko Kato and
  • Shiro Imagama
  • + 2 authors+ 0 author

9 June 2022

Magnetic resonance imaging (MRI) system has frequently observed degenerative changes in the cervical discs of healthy subjects. Although there are concerns regarding the link between an individual’s occupation and intervertebral disc degenerati...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
1,458 Views
19 Pages

Cervical cancer is one of the most common malignant tumors, with high incidence and mortality rates. Recent studies mainly adopt Artificial Intelligence (AI) models to detect cervical cells. Yet, due to the imperceptible symptoms of cervical cells, t...

  • Review
  • Open Access
17 Citations
6,502 Views
13 Pages

The Small Posterior Cranial Fossa Syndrome and Chiari Malformation Type 0

  • Enver I. Bogdanov,
  • Aisylu T. Faizutdinova and
  • John D. Heiss

17 September 2022

Patients showing typical Chiari malformation type 1 (CM1) signs and symptoms frequently undergo cranial and cervical MRI. In some patients, MRI documents >5 mm of cerebellar tonsillar herniation (TH) and the diagnosis of CM1. Patients with 3&ndash...

(This article belongs to the Special Issue Chiari 1 Malformation, Syringomyelia and Related Disorders: Advances in Diagnosis and Treatment for Adults and Children)
  • Article
  • Open Access
8 Citations
3,752 Views
11 Pages

Biomechanical Analysis of Allograft Spacer Failure as a Function of Cortical-Cancellous Ratio in Anterior Cervical Discectomy/Fusion: Allograft Spacer Alone Model

  • Ji-Won Kwon,
  • Hwan-Mo Lee,
  • Tae-Hyun Park,
  • Sung Jae Lee and ,
  • Young-Woo Kwon,
  • Seong-Hwan Moon and
  • Byung Ho Lee
  • + 2 authors+ 0 author

15 September 2020

The design and ratio of the cortico-cancellous composition of allograft spacers are associated with graft-related problems, including subsidence and allograft spacer failure. Methods: The study analyzed stress distribution and risk of subsidence acco...

(This article belongs to the Special Issue Musculoskeletal Research: Biomechanics and Biomaterials for the Treatment of Orthopedic Diseases)
  • Feature Paper
  • Article
  • Open Access
9 Citations
7,309 Views
12 Pages

Clinical and Radiological Characteristics of Cervical Spondylotic Myelopathy in Young Adults: A Retrospective Case Series of Patients under Age 30

  • Yoshiki Terashima,
  • Takashi Yurube,
  • Masatoshi Sumi,
  • Aritetsu Kanemura and ,
  • Koki Uno and
  • Kenichiro Kakutani
  • + 1 author+ 0 author

10 March 2023

Background and Objectives: Cervical spondylotic myelopathy (CSM) is a degenerative disease and occurs more frequently with age. In fact, the development of non-herniated CSM under age 30 is uncommon. Therefore, a retrospective case series was designe...

  • Review
  • Open Access
6 Citations
9,583 Views
22 Pages

7 August 2015

DNA viruses are known to be associated with a variety of different cancers. Human papillomaviruses (HPV) are a family of viruses and several of its sub-types are classified as high-risk HPVs as they are found to be associated with the development of...

(This article belongs to the Special Issue Next Generation Sequencing: New Developments and Discoveries in Virology)
  • Article
  • Open Access
3 Citations
2,510 Views
14 Pages

miR-29a Downregulates PIK3CA Expression and Inhibits Cervical Cancer Cell Dynamics: A Comparative Clinical Analysis

  • Hyorim Jeong,
  • Kangchan Choi,
  • Dasom Hwang,
  • Sunyoung Park and ,
  • Yong Serk Park and
  • Hyeyoung Lee
  • + 1 author+ 0 author

8 November 2024

HPV/pap tests are widely used for cervical cancer screening, playing a crucial role in early diagnosis and guiding future treatment options. However, approximately 50% of cervical cancer patients are diagnosed at an advanced stage, which is associate...

(This article belongs to the Special Issue Molecular Insights into Pathogenesis and Targeted Therapy of Gynaecological Cancers)
  • Article
  • Open Access
14 Citations
3,655 Views
16 Pages

Cervical HPV Infections, Sexually Transmitted Bacterial Pathogens and Cytology Findings—A Molecular Epidemiology Study

  • George Valasoulis,
  • Abraham Pouliakis,
  • Georgios Michail,
  • Ioulia Magaliou and ,
  • Christos Parthenis,
  • Niki Margari,
  • Christine Kottaridi,
  • Aris Spathis,
  • Danai Leventakou and
  • Ioannis G. Panayiotides
  • + 10 authors+ 5 authors

14 November 2023

Prevalent cervical HPV infection and high-risk HPV persistence consequences have been extensively investigated in the literature; nevertheless, any causative interrelations of other sexually transmitted bacterial infections (STIs) with cervical HPV i...

(This article belongs to the Special Issue Focus on Cervicovaginal Health: Microbiome, Sexually Transmitted Infections, and Beneficial Microbes)
  • Article
  • Open Access
2 Citations
2,676 Views
10 Pages

Clinical and Psychological Variables in Female Patients with Cervical Syndromes: A Cross-Sectional and Correlational Study

  • Sara Cabanillas-Barea,
  • Andoni Carrasco-Uribarren,
  • Ricardo Medrano-de-la-Fuente,
  • Sandra Jiménez-del-Barrio and ,
  • Pilar Pardos-Aguilella,
  • Silvia Pérez-Guillén and
  • Luis Ceballos-Laita
  • + 2 authors+ 0 author

29 November 2022

Background: The objectives of this study were: (1) to compare the pain intensity, cervical range of motion (ROM), psychological distress and kinesiophobia in patients with cervicogenic dizziness (CGD), tension-type headache (TTH), and mechanical chro...

(This article belongs to the Special Issue Mental and Behavioral Healthcare)
  • Article
  • Open Access
4 Citations
2,855 Views
8 Pages

Safety and Preliminary Efficacy of Cervical Paraspinal Interfascial Plane Block for Postoperative Pain after Pediatric Chiari Decompression

  • Jared M. Pisapia,
  • Tara M. Doherty,
  • Liana Grosinger,
  • Audrey Huang and ,
  • Carrie R. Muh,
  • Apolonia E. Abramowicz and
  • Jeff L. Xu
  • + 2 authors+ 0 author

Background: Surgery for lesions of the posterior fossa is associated with significant postoperative pain in pediatric patients related to extensive manipulation of the suboccipital musculature and bone. In this study, we assess the preliminary safety...

(This article belongs to the Special Issue Pain Management Practice and Research)
  • Article
  • Open Access
39 Citations
11,079 Views
18 Pages

2 July 2015

8-p-Hdroxybenzoyl tovarol (TAW) is a germacrane-type sesquiterpenoid that can be isolated from the roots of Ferula dissecta (Ledeb.) Ledeb. In this study, the growth inhibitory effects induced by TAW were screened on some types of tumor cells, and th...

(This article belongs to the Special Issue Bioactive Phytochemicals and Functional Food Ingredients in Fruits and Vegetables)
  • Brief Report
  • Open Access
4 Citations
4,034 Views
9 Pages

27 July 2023

Background: Historically, cervical cytology has been the standard method for detecting dysplastic cervical changes. However, extensive research has established that human papillomavirus (HPV) infection is a primary cause of these changes, necessitati...

(This article belongs to the Special Issue Novel Insights into Medical Oncology)
  • Article
  • Open Access
14 Citations
4,145 Views
11 Pages

Mapping of the Micro-Mechanical Properties of Human Root Dentin by Means of Microindentation

  • Michael Kucher,
  • Martin Dannemann,
  • Niels Modler,
  • Martina Romy Bernhard and ,
  • Christian Hannig and
  • Marie-Theres Weber
  • + 1 author+ 0 author

21 January 2021

The extensive knowledge of root dentin’s mechanical properties is necessary for the prediction of microstructural alterations and the teeth’s deformations as well as their fracture behavior. Standardized microindentation tests were applie...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
3 Citations
3,468 Views
12 Pages

To determine the impact of active muscle on the dynamic response of a pilot’s neck during simulated emergency ejection, a detailed three-dimensional (3D) cervical spine (C0–T1) finite element (FE) model integrated with active muscles was...

(This article belongs to the Special Issue Computational Biomechanics, Volume II)
  • Article
  • Open Access
6 Citations
4,728 Views
24 Pages

Approach to Radical Hysterectomy for Cervical Cancer in Pregnancy: Surgical Pathway and Ethical Considerations

  • Rocco Guerrisi,
  • Sarah Louise Smyth,
  • Lamiese Ismail,
  • Amanda Horne and ,
  • Federico Ferrari and
  • Hooman Soleymani majd
  • + 1 author+ 0 author

10 December 2022

Introduction. Cervical cancer is currently the fourth most common cancer in women and in the poorest countries this neoplasia still represents a widespread and potentially lethal disease. We present a rare case of cervical cancer in pregnancy, analyz...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
21 Citations
6,988 Views
16 Pages

Isolation, Characterization and Antiproliferative Activity of New Metabolites from the South African Endemic Red Algal Species Laurencia alfredensis

  • Godwin A. Dziwornu,
  • Mino R. Caira,
  • Jo-Anne de la Mare,
  • Adrienne L. Edkins and ,
  • John J. Bolton,
  • Denzil R. Beukes and
  • Suthananda N. Sunassee
  • + 2 authors+ 0 author

The marine red algae of the genus Laurencia have been widely studied for their structurally diverse and biologically active secondary metabolites. We report here the natural product investigation of the organic extract of a newly identified South Afr...

(This article belongs to the Special Issue Natural Product: A Continuing Source of Novel Drug Leads)
  • Review
  • Open Access
16 Citations
3,998 Views
21 Pages

The EPH/Ephrin System in Gynecological Cancers: Focusing on the Roots of Carcinogenesis for Better Patient Management

  • Iason Psilopatis,
  • Alexandros Pergaris,
  • Kleio Vrettou,
  • Gerasimos Tsourouflis and
  • Stamatios Theocharis

Gynecological cancers represent some of the most common types of malignancy worldwide. Erythropoietin-producing hepatocellular receptors (EPHs) comprise the largest subfamily of receptor tyrosine kinases, binding membrane-bound proteins called ephrin...

(This article belongs to the Special Issue Molecular Advances in Cancer Therapy)
  • Article
  • Open Access
11 Citations
4,435 Views
10 Pages

Risk Factors Associated with Post-Operative Complications in Multidisciplinary Treatment of Descending Necrotizing Mediastinitis

  • Maria Teresa Congedo,
  • Dania Nachira,
  • Mariano Alberto Pennisi,
  • Marco Chiappetta and ,
  • Giuseppe Calabrese,
  • Giuseppe Bello,
  • Claudio Parrilla,
  • Laura Franza,
  • Marcello Covino and
  • Elisa Meacci
  • + 10 authors+ 5 authors

28 October 2022

Background: Descending necrotizing mediastinitis (DNM) is a severe, life-threatening complication of oropharyngeal infections with cervical necrotizing fasciitis. In this study, we aimed to identify any possible factors that correlate with favorable...

(This article belongs to the Section General Surgery)
  • Brief Report
  • Open Access
7 Citations
3,643 Views
8 Pages

The T350G Variation of Human Papillomavirus 16 E6 Gene Prevails in Oropharyngeal Cancer from a Small Cohort of Greek Patients

  • Christine Kottaridi,
  • Panagiota Resta,
  • Danai Leventakou,
  • Katerina Gioti and ,
  • Ioannis Zygouras,
  • Alina-Roxani Gouloumi,
  • Georgios Sakagiannis,
  • Khalid J. Alzahrani,
  • Maria S. Venetikou and
  • Apostolos Beloukas
  • + 6 authors+ 1 author

4 August 2022

Recent trends have shown a dramatic rise in the incidence of oropharyngeal squamous cell carcinoma strongly associated with high-risk human papillomavirus (HPV) of type 16. The genetic variability of HPV16 has been extensively studied in cervical can...

(This article belongs to the Special Issue State-of-the-Art Virus Research in Greece)
  • Review
  • Open Access
220 Citations
21,928 Views
22 Pages

19 October 2016

Approximately 200 human papillomaviruses (HPVs) infect human epithelial cells, of which the alpha and beta types have been the most extensively studied. Alpha HPV types mainly infect mucosal epithelia and a small group of these causes over 600,000 ca...

(This article belongs to the Special Issue HPV Associated Cancers)
  • Article
  • Open Access
21 Citations
8,688 Views
14 Pages

Cytotoxic Oleanane-Type Triterpenoid Saponins from the Rhizomes of Anemone rivularis var. flore-minore

  • Xiaoyang Wang,
  • Minchang Wang,
  • Min Xu,
  • Yi Wang and ,
  • Haifeng Tang and
  • Xiaoli Sun
  • + 1 author+ 0 author

18 February 2014

Phytochemical investigation of the n-BuOH extract of the rhizomes of Anemone rivularis var. flore-minore led to the isolation of five new oleanane-type triterpenoid saponins 1–5, together with five known saponins 6–10. Their structures were determine...

(This article belongs to the Collection Bioactive Compounds)
  • Article
  • Open Access
330 Views
19 Pages

Comparison of Neurodynamic Test Response Between Patients with Frequent Episodic Tension-Type Headache and Migraine: An Exploratory Comparative Study

  • Leandro H. Caamaño-Barrios,
  • Ana Ostolaza-Guitian,
  • Rubén Cuevas-Rodríguez,
  • Juan Antonio Valera-Calero and ,
  • Fernando Galán-del-Río,
  • Sandra Sánchez-Jorge and
  • Ricardo Ortega-Santiago
  • + 2 authors+ 0 author

16 October 2026

Background/Objectives: Although migraine and frequent episodic tension-type headache (FETTH) may share sensory features, direct comparisons of responses to neurodynamic loading are scarce. Establishing whether responses differ may help distinguish sh...

(This article belongs to the Special Issue Clinical Rehabilitation and Management of Chronic Musculoskeletal Pain Conditions)
  • Article
  • Open Access
8 Citations
4,371 Views
12 Pages

Biomechanical Comparison of Posterior Fixation Combinations with an Allograft Spacer between the Lateral Mass and Pedicle Screws

  • Soo-Bin Lee,
  • Hwan-Mo Lee,
  • Tae-Hyun Park,
  • Sung Jae Lee and ,
  • Young-Woo Kwon,
  • Seong-Hwan Moon and
  • Byung Ho Lee
  • + 2 authors+ 0 author

19 October 2020

Background: There are a few biomechanical studies that describe posterior fixation methods with pedicle screws (PS) and lateral mass screws (LMS); the combination of both screw types and their effect on an allograft spacer in a surgically treated cer...

(This article belongs to the Special Issue Musculoskeletal Research: Biomechanics and Biomaterials for the Treatment of Orthopedic Diseases)
  • Article
  • Open Access
2 Citations
2,203 Views
21 Pages

Group and Individual Changes in Spinal Mobility During a 12-Week Rehabilitation Program Including Swimming in Horses with Axial Musculoskeletal Lesions

  • Baptiste Pécresse,
  • Claire Moiroud,
  • Sandrine Hanne-Poujade,
  • Chloé Hatrisse and ,
  • Emeline De Azevedo,
  • Virginie Coudry,
  • Sandrine Jacquet,
  • Fabrice Audigié and
  • Henry Chateau
  • + 4 authors+ 0 author

30 December 2025

Locomotor disorders involving the spine are a major cause of impaired performance and early retirement in sport horses. Swimming is increasingly incorporated into rehabilitation protocols, but its effects on spinal biomechanics remain poorly understo...

(This article belongs to the Special Issue Advances in Equine Sports Medicine, Therapy and Rehabilitation: 2nd Edition)
  • Article
  • Open Access
1 Citations
1,933 Views
10 Pages

27 December 2025

Background: Universal varicella vaccination has fundamentally altered the epidemiology of varicella-zoster virus (VZV) infections. While the incidence of primary varicella has declined, the characteristics of herpes zoster (HZ) in the post-vaccine ge...

(This article belongs to the Section Epidemiology and Vaccination)
  • Review
  • Open Access
15 Citations
6,275 Views
20 Pages

The Clinical Utility of Circulating HPV DNA Biomarker in Oropharyngeal, Cervical, Anal, and Skin HPV-Related Cancers: A Review

  • Ioana Maria Andrioaie,
  • Ionut Luchian,
  • Costin Dămian,
  • Giorgio Nichitean and ,
  • Elena Porumb Andrese,
  • Theodor Florin Pantilimonescu,
  • Bogdan Trandabăț,
  • Liviu Jany Prisacariu,
  • Dana Gabriela Budală and
  • Ramona Gabriela Ursu
  • + 7 authors+ 2 authors

Human papillomavirus (HPV) is recognized as being related to a wide variety of known cancers: cervical, oropharyngeal, anal, vaginal, penile, and skin. For some of these cancers, rigorous algorithms for screening, therapeutical interventions, and fol...

(This article belongs to the Special Issue Oncogenic Viruses: Advances in Molecular Diagnosis, Prevention Strategies and Therapy)
  • Interesting Images
  • Open Access
6 Citations
4,931 Views
6 Pages

Congenital Craniofacial Plexiform Neurofibroma in Neurofibromatosis Type 1

  • Antonella Cacchione,
  • Alessia Carboni,
  • Mariachiara Lodi,
  • Rita De Vito and ,
  • Andrea Carai,
  • Antonio Marrazzo,
  • Marina Macchiaiolo,
  • Ioan Paul Voicu,
  • Angela Mastronuzzi and
  • Giovanna Stefania Colafati
  • + 5 authors+ 0 author

We present a case demonstrating the performance of different radiographical imaging modalities in the diagnostic work-up of a patient with neurofibromatosis type 1 (NF1) and plexiform neurofibroma (PN). The newborn boy showed an expansive-infiltrativ...

(This article belongs to the Special Issue Advances in Pediatric Neuro-Oncology)
  • Review
  • Open Access
9 Citations
4,288 Views
15 Pages

Advances in Exosomes as Diagnostic and Therapeutic Biomarkers for Gynaecological Malignancies

  • Mengdan Miao,
  • Yifei Miao,
  • Yanping Zhu,
  • Junnan Wang and
  • Huaijun Zhou

28 September 2022

Background: Exosomes are extracellular vesicles that can be released by practically all types of cells. They have a diameter of 30–150 nm. Exosomes control the exchange of materials and information between cells. This function is based on its s...

(This article belongs to the Topic Women's Health and Aging)
  • Article
  • Open Access
12 Citations
4,485 Views
7 Pages

10 June 2022

Revision surgery after posterior fossa decompression for Chiari malformation is not uncommon and poses both strategic and technical challenges. We conducted a single-center retrospective cohort study including all adult patients who underwent revisio...

(This article belongs to the Special Issue Chiari 1 Malformation, Syringomyelia and Related Disorders: Advances in Diagnosis and Treatment for Adults and Children)
  • Review
  • Open Access
8 Citations
3,663 Views
12 Pages

VEGF as a Key Actor in Recurrent Respiratory Papillomatosis: A Narrative Review

  • Sandra Gazzini,
  • Raffaele Cerullo and
  • Davide Soloperto

Recurrent respiratory papillomatosis (RRP) is a benign disease of the upper aerodigestive tract caused by human papillomavirus (HPV) types 6 and 11. The clinical course is unpredictable and some patients, especially younger children, experience a hig...

(This article belongs to the Special Issue Molecular Mechanism of HPV’s Involvement in Cancers)
  • Article
  • Open Access
1 Citations
3,259 Views
14 Pages

Analytical Validation of NavDx+Gyn, a cfDNA-Based Fragmentomic Profiling Assay for HPV-Driven Gynecologic Cancers

  • Joshua Hutcheson,
  • David Conway,
  • Sunil Kumar,
  • Chloe Wiseman and ,
  • Syandan Chakraborty,
  • Evgeny Skrypkin,
  • Michael Horan,
  • Alicia Gunning,
  • Cassin Kimmel Williams and
  • Piyush B. Gupta
  • + 7 authors+ 2 authors

Background/Objectives: The NavDx+Gyn blood test detects and quantifies fourteen HPV types in various sample types to provide a reliable means of detecting and monitoring HPV-driven gynecologic cancers. NavDx+Gyn is an extension of the NavDx assay, wh...

(This article belongs to the Special Issue Advances in the Diagnosis and Management of Gynecological Oncology)
  • Article
  • Open Access
1,150 Views
23 Pages

Botulinum Toxin Type A in Spasticity and Cervical Dystonia: Practical Clinical Recommendations from a Mexican Multidisciplinary Panel of Specialist Injectors

  • Jorge Hernández Franco,
  • Salvador J. Santamaría Molina,
  • José J. Zorrilla Sánchez,
  • Jorge Carranza del Río and ,
  • Israel Sánchez Villavicencio,
  • Sofía D. Hernández,
  • Emmanuel Duvignau Dondé,
  • Héctor A. González Usigli,
  • Yadira S. González López and
  • Pedro I. Arias Vázquez
  • + 10 authors+ 5 authors

30 June 2026

Cervical dystonia and spasticity are debilitating neuromuscular disorders that substantially impair quality of life. Botulinum toxin type A (BoNT-A) is a cornerstone therapy; however, heterogeneity in dosing, muscle selection, and guidance techniques...

(This article belongs to the Special Issue Botulinum Toxin in Neuro-Rehabilitation: Expanding Horizons in Spasticity and Beyond)
  • Review
  • Open Access
9 Citations
4,319 Views
9 Pages

Papillary Thyroid Carcinoma with Desmoid-Type Fibromatosis: Review of Published Cases

  • Abdallah Roukain,
  • Stefano La Rosa,
  • Massimo Bongiovanni,
  • Marie Nicod Lalonde and ,
  • Valérie Cristina,
  • Michael Montemurro,
  • Stephane Cochet,
  • Alexandra Luquain,
  • Peter A. Kopp and
  • Gerasimos P. Sykiotis
  • + 5 authors+ 0 author

6 September 2021

Desmoid-type fibromatosis (DTF) is a very rare variant of papillary thyroid carcinoma (PTC). It is essentially a dual tumor with a component of classical PTC with malignant epithelial proliferation (BRAF-mutated) and another component of mesenchymal...

(This article belongs to the Special Issue Follicular Cell-Derived Thyroid Carcinomas: Current Status and Future Prospects)
  • Case Report
  • Open Access
1 Citations
3,170 Views
11 Pages

31 October 2023

Motor recovery following a complete spinal cord injury is not likely. This is partially due to insurance limitations. Rehabilitation strategies for individuals with this type of severe injury focus on the compensation for the activities of daily livi...

(This article belongs to the Special Issue Clinical Application of Physical Therapy in Neurorehabilitation)
  • Review
  • Open Access
16 Citations
12,600 Views
44 Pages

Unveiling the Multifaceted Pharmacological Actions of Indole-3-Carbinol and Diindolylmethane: A Comprehensive Review

  • Yadava Srikanth,
  • Dontiboina Harikrishna Reddy,
  • Vinjavarapu Lakshmi Anusha,
  • Naresh Dumala and ,
  • Matte Kasi Viswanadh,
  • Guntupalli Chakravarthi,
  • Buchi N. Nalluri,
  • Ganesh Yadagiri and
  • Kakarla Ramakrishna
  • + 4 authors+ 0 author

6 March 2025

Cruciferae family vegetables are remarkably high in phytochemicals such as Indole-3-carbinol (I3C) and Diindolylmethane (DIM), which are widely known as nutritional supplements. I3C and DIM have been studied extensively in different types of cancers...

(This article belongs to the Special Issue Bioactive Metabolites from Plants as Potential Treatments for Global Diseases)
  • Article
  • Open Access
942 Views
17 Pages

Proposal for an Expanded Classification of the Superficial Musculoaponeurotic System (SMAS) in the Human Forehead, Based on Anatomical and Microscopic Study

  • Yuriy L. Vasil’ev,
  • Olesya Kytko,
  • Elena O. Bakhrushina,
  • Irina Smilyk and ,
  • Pavel Sarygin and
  • Dmitriy Kalinin
  • + 1 author+ 0 author

2 May 2026

Introduction. The superficial musculoaponeurotic system (SMAS) is fundamental for facial soft tissue support and surgical rejuvenation. Although its morphology in the midface and neck is well characterized, the structure of its cranial extension to t...

(This article belongs to the Section Physiology and Pathology)
  • Article
  • Open Access
1,404 Views
15 Pages

HIF-2α Interaction with Ataxin-10 Enhances HIF-2α Binding to Its Target Gene Promoters

  • Aikaterini Diseri,
  • Ioanna-Maria Gkotinakou,
  • Christina Befani,
  • Ioannis Pappas and ,
  • Martina Samiotaki,
  • George Panayotou and
  • Panagiotis Liakos
  • + 2 authors+ 0 author

27 October 2025

The master transcription factors that control cell adaptation under hypoxia are known as hypoxia-inducible factors or HIFs. HIF-2α is the second isoform, which has been studied less extensively, and its expression is limited to particular cell...

(This article belongs to the Special Issue 25th Anniversary of IJMS: Updates and Advances in Molecular Pathology, Diagnostics, and Therapeutics)
  • Article
  • Open Access
18 Citations
6,909 Views
16 Pages

6 August 2019

Recent developments in our understanding of the interactions between long non-coding RNAs (lncRNAs) and cellular components have improved treatment approaches for various human diseases including cancer, vascular diseases, and neurological diseases....

(This article belongs to the Special Issue Selected Papers from the International Conference on Intelligent Biology and Medicine (ICIBM 2019))
  • Article
  • Open Access
10 Citations
6,892 Views
15 Pages

The purpose of this study was to investigate and compare the passive joint range of motion (PROM) and muscle strength in prepubertal rhythmic gymnasts (RGs), artistic gymnasts (AGs), and a control group (CG) of the same age. A total of 54 prepubertal...

(This article belongs to the Special Issue Efficiency in Kinesiology: Innovative Approaches in Enhancing Motor Skills for Athletic Performance 2.0)
  • Review
  • Open Access
5 Citations
5,842 Views
28 Pages

Cancer is one of the leading causes of human death among all major diseases. Metal-based complexes are considered as the most promising vital part in the existing arsenal of cytotoxic candidates used in cancer therapy and diagnostics. The efforts of...

(This article belongs to the Special Issue Rational Design of Pharmacologically Active Metal-Based Compounds)
  • Article
  • Open Access
3 Citations
1,722 Views
12 Pages

Differences in Vaginal Microbiota Composition Between Infertile and Fertile Patients: A Prospective Study

  • Pei-Chen Chen,
  • Shih-Fen Chen,
  • Wei-Tung Hung,
  • Yu-Ying Lin and ,
  • Ling-Chun Lin,
  • Jen-Hung Wang and
  • Pao-Chu Chen
  • + 2 authors+ 0 author

9 October 2025

Background/Objectives: Dysbiosis of the vaginal microbiota, particularly the loss of Lactobacillus spp. dominance, is linked to female infertility. While community state types (CSTs) I–III and V have been studied extensively, CST IV remains und...

(This article belongs to the Special Issue New Insights into the Diagnosis of Gynecological Diseases)
  • Article
  • Open Access
45 Citations
4,741 Views
18 Pages

Radiation Enhancer Effect of Platinum Nanoparticles in Breast Cancer Cell Lines: In Vitro and In Silico Analyses

  • Marie Hullo,
  • Romain Grall,
  • Yann Perrot,
  • Cécile Mathé and ,
  • Véronique Ménard,
  • Xiaomin Yang,
  • Sandrine Lacombe,
  • Erika Porcel,
  • Carmen Villagrasa and
  • Emmanuelle Bourneuf
  • + 6 authors+ 1 author

High-Z metallic nanoparticles (NPs) are new players in the therapeutic arsenal against cancer, especially radioresistant cells. Indeed, the presence of these NPs inside malignant cells is believed to enhance the effect of ionizing radiation by locall...

(This article belongs to the Special Issue Nanoparticle-Based Radiosensitization 2.0)
  • Article
  • Open Access
5 Citations
3,127 Views
27 Pages

16 November 2023

The aim of the research is to compare the head displacements of volunteers with the head displacements of the KPSIT C50 dummy, taking into account the change of vehicle seat belts. Unfortunately, sudden braking or collisions between vehicles is becom...

(This article belongs to the Special Issue Traffic Flow, Road Safety, and Sustainable Transportation)
  • Article
  • Open Access
2 Citations
2,635 Views
14 Pages

Assessment of Pain Complaints and Perioperative and Delayed Complications of Hysteroscopy Performed Under Local Anesthesia—A Retrospective Analysis

  • Agnieszka Lach,
  • Maciej Wilczak,
  • Adam Malinger,
  • Adrian Nowak and ,
  • Piotr Piekarski,
  • Adrian Mruczyński,
  • Kinga Bednarek and
  • Karolina Chmaj-Wierzchowska
  • + 3 authors+ 0 author

9 August 2025

Modern, small-diameter endoscopic instruments, such as resectoscopes (e.g., the GUBBINI System) and mini-hysteroscopes, are widely used in clinical practice. These tools allow endoscopic procedures to be conducted without cervical dilation, often in...

(This article belongs to the Special Issue Advanced Hysteroscopic Technology for Gynecological Disease)
  • Article
  • Open Access
5 Citations
2,917 Views
11 Pages

A Comprehensive Characterization of Patients with Spinal Cord Neurosarcoidosis: A Single Center Cross-Sectional Study of Clinical Outcomes

  • Rami Al-Hader,
  • Justin Nofar,
  • Ahmed Mohamedelkhair,
  • Muhammad Affan and ,
  • Lonni R. Schultz and
  • Mirela Cerghet
  • + 1 author+ 0 author

27 August 2024

Background/Objective: To describe the clinical features and radiological outcomes of patients with spinal cord neurosarcoidosis, treatments, and long-term follow-up for this rare disorder. Methods: A cross-sectional, retrospective medical chart revie...

(This article belongs to the Section Clinical Neurology)
  • Article
  • Open Access
513 Views
22 Pages

12 September 2026

CD24 is an emerging innate immune checkpoint that regulates inflammatory and antiviral immune responses through interactions with Siglec family receptors. Although CD24 has been extensively studied in immune regulation and has recently gained attenti...

(This article belongs to the Section Immunology)
  • Article
  • Open Access
10 Citations
3,693 Views
10 Pages

Extended Genotyping to Stratify the Risk of CIN2+ in Women with Persistent HPV Infection, Negative Cytology and Type 3 Transformation Zone

  • Maria Teresa Bruno,
  • Gaetano Valenti,
  • Antonino Giovanni Cavallaro,
  • Ilenia Palermo and ,
  • Tiziana Aiello,
  • Jessica Farina,
  • Marco Marzio Panella and
  • Liliana Mereu
  • + 3 authors+ 0 author

10 May 2024

Persistent human papillomavirus (HPV) infection is recognized as a major risk factor for cervical cancer. Women with persistent HPV and negative cytology are at greater risk of CIN2+ than women with negative infection. The diagnosis becomes more comp...

(This article belongs to the Section Cancer Causes, Screening and Diagnosis)

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