Molecular Insights into Pathogenesis and Targeted Therapy of Gynaecological Cancers

Dear Colleagues,

Gynaecological cancers, including ovarian, cervical, and endometrial cancers, remain a significant global health burden, with high morbidity and mortality rates. Despite advancements in diagnosis and treatment, the complex molecular mechanisms driving these cancers are not fully understood, hindering the development of effective therapies.

In this Special Issue, we will delve into the intricate molecular biology underlying gynaecological cancers, in particular by uncovering the molecular mechanisms that drive the pathogenesis of these cancers and identifying genetic mutations, epigenetic alterations, and the dysregulation of critical signaling pathways. By understanding these molecular foundations, we will discover novel biomarkers for early detection and prognostic evaluation. We also seek to explore advancements in targeted therapies, emphasizing the development and application of molecular-targeted agents. This includes examining the efficacy and mechanisms of action of new therapeutic drugs, immunotherapies, and personalized medicine approaches tailored to the molecular profiles of individual patients.

Contributions, including original research articles and comprehensive reviews, that provide significant insights into the molecular biology of gynaecological cancers and pave the way for innovative therapeutic interventions are highly encouraged.

Prof. Dr. Stergios Boussios
Guest Editor

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